Academic literature on the topic 'Gene therapy'
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Journal articles on the topic "Gene therapy":
Goyal, Anjana, Reena Doomra, Aayushi Garg, and Kruthiventi Hemalata. "CRISPR Gene Therapy in Dentistry." Asian Pacific Journal of Health Sciences 6, no. 2 (June 2019): 182–83. http://dx.doi.org/10.21276/apjhs.2019.6.2.26.
Gawthorpe, Paula. "Gene Therapy Gene Therapy." Nursing Standard 17, no. 33 (April 30, 2003): 29. http://dx.doi.org/10.7748/ns2003.04.17.33.29.b25.
M. Gordon, Erlinda, Joshua R. Ravicz, Sant P. Chawla, Christopher W. Szeto, Sant P. Chawla, Michael A. Morse, Frederick L. Hall, and Erlinda M. Gordon. "CCNG1 oncogene: a novel biomarker for cancer therapy /gene therapy." Cancer Research and Cellular Therapeutics 5, no. 4 (August 30, 2021): 01–09. http://dx.doi.org/10.31579/2640-1053/090.
Sose, Mr Aadesh S., and Mr Pramod M. Bhosale. "A Review on Gene Therapy for Cancer." International Journal of Research Publication and Reviews 4, no. 4 (April 2023): 3058–63. http://dx.doi.org/10.55248/gengpi.4.423.36713.
&NA;. "Gene therapy." Inpharma Weekly &NA;, no. 1161 (October 1998): 12. http://dx.doi.org/10.2165/00128413-199811610-00018.
&NA;. "Gene therapy." Inpharma Weekly &NA;, no. 1184 (April 1999): 8. http://dx.doi.org/10.2165/00128413-199911840-00015.
Peroutka, Christina, and Joann Bodurtha. "Gene Therapy." Pediatrics in Review 41, no. 11 (November 2020): 606–8. http://dx.doi.org/10.1542/pir.2019-0224.
&NA;. "Gene therapy." Inpharma Weekly &NA;, no. 1120 (January 1998): 4. http://dx.doi.org/10.2165/00128413-199811200-00004.
Whartenby, Katharine A., Aizen J. Marrogi, and Scott M. Freeman. "Gene Therapy." Drugs 50, no. 6 (December 1995): 951–58. http://dx.doi.org/10.2165/00003495-199550060-00003.
Williamson, Robert. "Gene therapy." Australian Prescriber 20, no. 3 (July 1, 1997): 72–73. http://dx.doi.org/10.18773/austprescr.1997.062.
Dissertations / Theses on the topic "Gene therapy":
Vasanwala, Farha Huseini. "Gene manipulations for cancer gene therapy." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/289776.
Santos, João Miguel Almeida. "Gene therapy: development of a new nanocarrier system for mitochondrial gene therapy." Master's thesis, Universidade da Beira Interior, 2013. http://hdl.handle.net/10400.6/1627.
As mitocôndrias são organelos únicos pois possuem o seu próprio genoma, o ADN mitocondrial (ADNmt). Apesar de bastante pequeno quando comparado com o ADN nuclear (ADNn), mutações ao nível do ADNmt são bastante frequentes devido à falta de mecanismos de protecção e de reparação. Como consequência, citopatias e doenças associadas à mitocôndria são bastante frequentes afectando essencialmente órgãos e tecidos onde existe muito dispêndio de energia como é o caso dos músculos e do cérbero. Logo, o desenvolvimento de um novo e eficiente protocolo para terapia génica mitocondrial (MGT) é visto como uma proposta aliciante. Durante esta tese de Mestrado, tentamos criar um novo nanosistema que consiga entregar eficazmente ADN plasmídico (pDNA) à mitocôndria para que no futuro possa ser usado em terapia génica mitocondrial (MGT). Assim, este projecto de investigação pode ser dividido em três etapas principais: 1. O isolamento e purificação de três plasmídeos (pUC19, pVAX1-LacZ e pcDNA3-myc-FLNa S2152A); 2. A síntese e caracterização de nanopartículas com afinidade para a mitocôndria; 3. O estudo da capacidade das nanopartículas efectuarem transfecção celular e dirigirem-se à mitocôndria; As nanopartículas desenvolvidas, através do método de co-precipitação oferecem-nos qualidades únicas como a sua biocompatibilidade, alta eficiência de encapsulamento de ADN e baixo custo de produção. A transfecção celular foi alcançada com sucesso sendo que, tais resultados, podem contribuir em grandes avanços na correcção de defeitos mitocondriais, oferecendo-nos uma nova estratégia terapêutica no combate a diversas patologias desde o cancro, às doenças de Parkinson e Alzheimer.
Nanda, Dharminderkoemar. "Gene therapy for gliomas." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/13140.
Hayes, E. A. L. "Anti-angiogenic gene therapy." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603877.
Bilsland, Alan. "Telomerase directed gene therapy." Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272871.
Katabi, Maha M. "Transcriptional targeting of suicide genes in cancer gene therapy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0021/NQ55345.pdf.
Morin, Kevin Wayne. "Scintigraphic imaging during gene therapy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq21605.pdf.
Singwi, Sanjeev. "HIV gene therapy using nucleases." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0001/MQ46100.pdf.
Horst, Maarten ter. "Gene therapy of malignant gliomas." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2008. http://hdl.handle.net/1765/10864.
Lau, Cara Jean. "Gene therapy for malignant gliomas." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18478.
Les gliomes sont des tumeurs primaires de cerveau les plus communes retrouvées dans les adultes. La survie médiane des patients diagnostiqués avec la forme la plus maligne, le glioblastome multiforme (GBM), est de 9 à 12 mois et a peu changé au cours des années en dépit des avances en technologie médicale. La thérapie génique peut offrir de nouvelles solutions pour traiter cette maladie résistante. Durant nos travaux, nous avons examiné trois stratégies différentes de thérapie génique Dans notre première étude, nous avons examiné l'efficacité de la thérapie visée à corriger des anomalies communes retrouvées dans les gliomes, comprenant l'amplification/mutation de récepteurs de type tyrosine kinase (RTK) et la perte de PTEN, qui mènent en conséquence à une voie activée de PI3K/Akt. Sans PTEN, les facteurs de transcription FOXO sont inactivés, et la cellule devient résistante à l'arrêt du cycle cellulaire et à l'apoptose. En utilisant un vecteur adénoviral (AdV) exprimant une protéine activée du mutant FOXO1 (AdFOXO1;AAA.), nous avons reconstitué les signaux pour l'arrêt du cycle cellulaire et l'apoptose in vitro ainsi que in vivo. Deuxièmement, nous avons examiné la capacité thérapeutique d'un nouveau vecteur adénovirale qui a la capacité de se répliquer sans provoquer de lyse cellulaire et qui exprime en plus la protéine de fusion uracile phosphoribosyltransférase/cytosine déaminase (CU). La protéine CU peut convertir le promédicament non-toxique, le 5-fluorocytosine (5-FC) à la drogue chimiothérapeutique diffusible, le 5-fluorouracile (5-FU) qui a comme cible des cellules en division cellulaire. In vitro, les vecteurs à capacité de répliquation étaient meilleurs que ceux qui ne pouvaient pas se répliquer. In vivo, le vecteur en présence du 5-FC a prolongé la survie de deux modès animaux (avec et sans sytèmes immunitaires). Dans un dernier temps, nous avons étudié une méthode pour exprimer l'IF
Books on the topic "Gene therapy":
Xanthopoulos, Kleanthis G., ed. Gene Therapy. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72160-1.
Blankenstein, Thomas, ed. Gene Therapy. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-7011-5.
Sobol, R. E., K. J. Scanlon, and E. Nestaas, eds. Gene Therapy. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-03577-1.
Giacca, Mauro. Gene Therapy. Milano: Springer Milan, 2010. http://dx.doi.org/10.1007/978-88-470-1643-9.
Kelly, Evelyn B. Gene therapy. Westport, Conn: Greenwood Press, 2007.
NATO, Study Institute "Gene Therapy" (1997 Spetsai Greece). Gene therapy. Berlin: Springer, 1998.
Giacca, Mauro. Gene therapy. Dordrecht: Springer, 2010.
1952-, Sobol Robert E., ed. Gene therapy. Berlin: Springer-Verlag, 1998.
Dr, Cooper David N., and Lemoine Nicholas R, eds. Gene therapy. Oxford, UK: Bios Scientific Publishers, 1996.
Naff, Clay Farris. Gene therapy. Edited by Naff Clay Farris. Detroit: Thomson/Gale, 2005.
Book chapters on the topic "Gene therapy":
Lee, Thomas F. "Gene Therapy." In Gene Future, 127–63. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2760-6_6.
Cornetta, Kenneth. "Gene Therapy." In Molecular Genetic Pathology, 717–29. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-405-6_29.
Douglas, Joanne T., and David T. Curiel. "Gene Therapy." In Molecular Biology of the Lung, 1–20. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8784-7_1.
Choi, Vivian W., and R. Jude Samulski. "Gene Therapy." In Vogel and Motulsky's Human Genetics, 867–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-37654-5_40.
Rohini, K. "Gene Therapy." In Advances in Biotechnology, 41–54. New Delhi: Springer India, 2013. http://dx.doi.org/10.1007/978-81-322-1554-7_4.
Khan, Manzoor M. "Gene Therapy." In Immunopharmacology, 363–96. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30273-7_11.
Tanabe, Kenneth K., and James C. Cusack. "Gene Therapy." In Surgery, 1881–900. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-57282-1_86.
Huh, Warner K., Mack N. Barnes, F. Joseph Kelly, and Ronald D. Alvarez. "Gene Therapy." In Ovarian Cancer, 133–57. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4757-3587-1_6.
Swazo, Norman K. "Gene Therapy." In Encyclopedia of Global Bioethics, 1–9. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-05544-2_213-1.
Taura, Akiko. "Gene Therapy." In Regenerative Medicine for the Inner Ear, 215–21. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54862-1_23.
Conference papers on the topic "Gene therapy":
"Advances in Gene Therapy." In International Conference on Cellular & Molecular Biology and Medical Sciences. Universal Researchers (UAE), 2016. http://dx.doi.org/10.17758/uruae.ae0916417.
. Shcherbakova, S. A., P. E. Karitskaya, A. S. Chesnokova, I. O. Karpets, I. V. Evgenov, and D. V. Tseylikman. "DIFFERENTIALLY EXPRESSED GENES PREDICTING RESPONSE TO TAMOXIFEN THERAPY IN BREAST CANCER PATIENTS." In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-40.
Salimova, A. A., V. D. Drozd, D. S. Rybalko, A. A. Eldeeb, A. A. Dedovskayav, and D. M. Kolpashchikov. "ANTISENSE OLIGONUCLEOTIDES RELEASING CASSETTE FOR CANCER THERAPY." In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-49.
Jiang, Xingyu. "Nanocluster-enabled Gene Therapy." In The 7th International Multidisciplinary Conference on Optofluidics 2017. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/optofluidics2017-04542.
Sakr, N. "DEVELOPMENT OF GENE THERAPY FOR CAH." In Конференция «Перспективы применения генной терапии и биомедицинского клеточного продукта» с блоком летней школы для молодых ученых. Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр эндокринологии» Министерства здравоохранения Российской Федерации, 2022. http://dx.doi.org/10.14341/gnct-2022-51.
Morgan, Jeffrey R. "Genetic Strategies for Tissue Engineering." In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-1165.
Vahedi, Golnaz, Babak Faryabi, Jean-Francois Chamberland, Aniruddha Datta, and Edward Dougherty. "Modeling cyclic therapy in gene regulatory networks." In 2008 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS). IEEE, 2008. http://dx.doi.org/10.1109/gensips.2008.4555670.
Sirsi, Shashank R., Darrell Yamashiro, Jessica Kandel, and Mark Borden. "Polyplex-microbubbles for ultrasound-mediated gene therapy." In ICA 2013 Montreal. ASA, 2013. http://dx.doi.org/10.1121/1.4801416.
Atsumi, N., A. Pilou, I. Pringle, RC Ashworth, C. Meng, M. Chan, DR Gill, et al. "S120 Gene therapy for pulmonary alveolar proteinosis." In British Thoracic Society Winter Meeting 2017, QEII Centre Broad Sanctuary Westminster London SW1P 3EE, 6 to 8 December 2017, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2017. http://dx.doi.org/10.1136/thoraxjnl-2017-210983.126.
Mokkapati, Sharada, Jon Duplisea, Michael Metcalfe, Amy Lim, Vikram Narayan, Devin Plote, Debashish Sundi, et al. "Abstract IA21: Intravesical gene therapy for NMIBC." In Abstracts: AACR Special Conference on Bladder Cancer: Transforming the Field; May 18-21, 2019; Denver, CO. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1557-3265.bladder19-ia21.
Reports on the topic "Gene therapy":
Higgins, Paul J. Inducible Anti-Angiogenic Gene Therapy. Fort Belvoir, VA: Defense Technical Information Center, May 2005. http://dx.doi.org/10.21236/ada437209.
Agarwal, Nitin, Jorgen Magnus, John Kerwin, Charlotte Holmes, Sy Gebrekidan, Don Powers, Emily Moran, et al. Gene therapy process manufacturing maps. BioPhorum, September 2020. http://dx.doi.org/10.46220/2020cgt003.
Hayward, Simon W. Therapy Selection by Gene Profiling. Fort Belvoir, VA: Defense Technical Information Center, May 2008. http://dx.doi.org/10.21236/ada491350.
Hayward, Simon W. Therapy Selection by Gene Profiling. Fort Belvoir, VA: Defense Technical Information Center, April 2005. http://dx.doi.org/10.21236/ada454306.
Hayward, Simon W. Therapy Selection by Gene Profiling. Fort Belvoir, VA: Defense Technical Information Center, April 2004. http://dx.doi.org/10.21236/ada426169.
Higgins, Paul J. Inducible Anti-Angiogenic Gene Therapy. Fort Belvoir, VA: Defense Technical Information Center, May 2004. http://dx.doi.org/10.21236/ada427186.
Baylink, David J. Gene Therapy for Fracture Repair. Fort Belvoir, VA: Defense Technical Information Center, December 2003. http://dx.doi.org/10.21236/ada431895.
Segal, David J. Gene Therapy for Childhood Neurofibromatosis. Fort Belvoir, VA: Defense Technical Information Center, May 2014. http://dx.doi.org/10.21236/ada609751.
Buchsbaum, Donald J. Radiopharmaceutical and Gene Therapy Program. Office of Scientific and Technical Information (OSTI), February 2006. http://dx.doi.org/10.2172/875908.
Lau, William. Gene Therapy for Fracture Repair. Fort Belvoir, VA: Defense Technical Information Center, May 2007. http://dx.doi.org/10.21236/ada474569.