Journal articles on the topic 'Gene di fusione'
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Padella, Antonella, Giorgia Simonetti, Giulia Paciello, Anna Ferrari, Elisa Zago, Carmen Baldazzi, Viviana Guadagnuolo, et al. "RNA Sequencing Reveals Novel and Rare Fusion Transcripts in Acute Myeloid Leukemia." Blood 126, no. 23 (December 3, 2015): 3627. http://dx.doi.org/10.1182/blood.v126.23.3627.3627.
Full textSong, Xiaowen, Qisheng Zhong, Guifang Peng, Yanhao Ji, Yuemei Zhang, Jing Tang, Jia Xie, Jingxiu Bi, Fan Feng, and Bin Li. "Functional characterization of a special dicistronic transcription unit encoding histone methyltransferase su(var)3-9 and translation regulator eIF2γ in Tribolium castaneum." Biochemical Journal 477, no. 16 (August 28, 2020): 3059–74. http://dx.doi.org/10.1042/bcj20200444.
Full textSteger, David J., Martina I. Lefterova, Lei Ying, Aaron J. Stonestrom, Michael Schupp, David Zhuo, Adam L. Vakoc, et al. "DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells." Molecular and Cellular Biology 28, no. 8 (February 19, 2008): 2825–39. http://dx.doi.org/10.1128/mcb.02076-07.
Full textGough, Sheryl M., Fan Lee, Yang Jo Chung, Robert L. Walker, Fan Yang, Yuelin (Jack) Zhu, Yi Ning, Paul S. Meltzer, and Peter Aplan. "A NUP98-PHF23 Transgenic Mouse Model Develops AML and T-ALL." Blood 118, no. 21 (November 18, 2011): 2467. http://dx.doi.org/10.1182/blood.v118.21.2467.2467.
Full textKlauck, Gisela, Diego O. Serra, Alexandra Possling, and Regine Hengge. "Spatial organization of different sigma factor activities and c-di-GMP signalling within the three-dimensional landscape of a bacterial biofilm." Open Biology 8, no. 8 (August 2018): 180066. http://dx.doi.org/10.1098/rsob.180066.
Full textHay, Iain D., Uwe Remminghorst, and Bernd H. A. Rehm. "MucR, a Novel Membrane-Associated Regulator of Alginate Biosynthesis in Pseudomonas aeruginosa." Applied and Environmental Microbiology 75, no. 4 (December 16, 2008): 1110–20. http://dx.doi.org/10.1128/aem.02416-08.
Full textYe, Xiaoqing, Gang Chen, Jia Jin, Binzhong Zhang, Yinda Wang, Zhenhai Cai, and Fei Ye. "The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein- Protein Interaction." Current Medicinal Chemistry 27, no. 33 (October 8, 2020): 5530–42. http://dx.doi.org/10.2174/0929867326666190528080514.
Full textDeshpande, Aniruddha J., Liying Chen, Amit U. Sinha, Nan Zhu, David Chen, Jenny Chang, Andrei V. Krivtsov, Kathrin Bernt, James E. Bradner, and Scott A. Armstrong. "Regulation Of Normal and Malignant Hoxa Gene Expression Through Higher H3K79 Methylated States." Blood 122, no. 21 (November 15, 2013): 2492. http://dx.doi.org/10.1182/blood.v122.21.2492.2492.
Full textXu, Siyuan, Siqing Wang, Shenghui Xing, Dingdang Yu, Bowen Rong, Hai Gao, Mengyao Sheng, et al. "KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2." Blood Advances 5, no. 17 (August 27, 2021): 3241–53. http://dx.doi.org/10.1182/bloodadvances.2020002819.
Full textBushweller, John H., Charles Schmidt, Nicholas Achille, Aravinda Kuntimaddi, Adam Boulton, Benjamin Leach, Shubin Zhang, and Nancy J. Zeleznik-Le. "Direct Binding of BCOR, but Not CBX8, to MLL-AF9 Is Essential for MLL-AF9 Leukemia Via Regulation of the EYA1/SIX1 Gene Network." Blood 132, Supplement 1 (November 29, 2018): 1316. http://dx.doi.org/10.1182/blood-2018-99-111388.
Full textBoer, Judith M., Maria Grazia Valsecchi, Femke M. Hormann, Zeljko Antic, Marketa Zaliova, Claire Schwab, Giovanni Cazzaniga, et al. "NUTM1-Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study." Blood 136, Supplement 1 (November 5, 2020): 25–26. http://dx.doi.org/10.1182/blood-2020-139376.
Full textIbrahim, Eid I., Kotb A. Attia, Abdelhalim I. Ghazy, Kimiko Itoh, Fahad N. Almajhdi, and Abdullah A. Al-Doss. "Molecular Characterization and Functional Localization of a Novel SUMOylation Gene in Oryza sativa." Biology 11, no. 1 (December 31, 2021): 53. http://dx.doi.org/10.3390/biology11010053.
Full textDi Gregorio, A., and M. Levine. "Regulation of Ci-tropomyosin-like, a Brachyury target gene in the ascidian, Ciona intestinalis." Development 126, no. 24 (December 15, 1999): 5599–609. http://dx.doi.org/10.1242/dev.126.24.5599.
Full textBoustead, JN, CC Martin, JK Oeser, CA Svitek, SI Hunter, JC Hutton, and RM O'Brien. "Identification and characterization of a cDNA and the gene encoding the mouse ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein." Journal of Molecular Endocrinology 32, no. 1 (February 1, 2004): 33–53. http://dx.doi.org/10.1677/jme.0.0320033.
Full textWozniak, Christopher E., Changhan Lee, and Kelly T. Hughes. "T-POP Array Identifies EcnR and PefI-SrgD as Novel Regulators of Flagellar Gene Expression." Journal of Bacteriology 191, no. 5 (December 29, 2008): 1498–508. http://dx.doi.org/10.1128/jb.01177-08.
Full textApfel, Christian M., Béla Takács, Michael Fountoulakis, Martin Stieger, and Wolfgang Keck. "Use of Genomics To Identify Bacterial Undecaprenyl Pyrophosphate Synthetase: Cloning, Expression, and Characterization of the Essential uppS Gene." Journal of Bacteriology 181, no. 2 (January 15, 1999): 483–92. http://dx.doi.org/10.1128/jb.181.2.483-492.1999.
Full textWiethaus, Jessica, Alexandra Müller, Meina Neumann, Sandra Neumann, Silke Leimkühler, Franz Narberhaus, and Bernd Masepohl. "Specific Interactions between Four Molybdenum-Binding Proteins Contribute to Mo-Dependent Gene Regulation in Rhodobacter capsulatus." Journal of Bacteriology 191, no. 16 (June 5, 2009): 5205–15. http://dx.doi.org/10.1128/jb.00526-09.
Full textHodges, Vivien M., Susan Rainey, Victoria Smyth, Ken Mills, Terence R. J. Lappin, and A. Peter Maxwell. "PHF23: A Novel Erythropoietin-Induced Gene Associated with AML and MDS." Blood 110, no. 11 (November 16, 2007): 3178. http://dx.doi.org/10.1182/blood.v110.11.3178.3178.
Full textStaak, Jan O., David Colcher, Scott Lauder, Jianyi Wang, Stephen D. Gillies, and Andrew A. Raubitschek. "The Novel De-Immunized Anti-CD20-IL-2 Immunocytokine DI-Leu16-IL-2 Is Effective in SCID Mice Bearing Rituximab-Resistant Human Lymphoma Xenografts." Blood 104, no. 11 (November 16, 2004): 3288. http://dx.doi.org/10.1182/blood.v104.11.3288.3288.
Full textHormaeche, Itsaso, Kim L. Rice, Arthur Zelent, Melanie J. McConnell, and Jonathan D. Licht. "PLZF-RARα Utilizes the Histone Methyl Transferase G9a/GLP and the Histone Demethylase LSD1 to Repress RARα Target Genes and Block Myeloid Differentiation." Blood 112, no. 11 (November 16, 2008): 198. http://dx.doi.org/10.1182/blood.v112.11.198.198.
Full textSuriano, Marco, Giovanni Martinelli, Angela Poerio, Marilina Amabile, Gianantonio Rosti, Fausto Castagnetti, Ilaria Iacobucci, et al. "Evaluation of the GeneXpert Assay for the Monitoring of BCR-ABL Transcript Levels In Chronic Myeloid Leukemia (CML) Patients: Preliminary Results of a Comparison with the Manual and Traditional Manual TaqMan RQ-PCR Assay." Blood 116, no. 21 (November 19, 2010): 4831. http://dx.doi.org/10.1182/blood.v116.21.4831.4831.
Full textVANHOOREN, Johannes C. T., Peter MARYNEN, Guy P. MANNAERTS, and Paul P. VAN VELDHOVEN. "Evidence for the existence of a pristanoyl-CoA oxidase gene in man." Biochemical Journal 325, no. 3 (August 1, 1997): 593–99. http://dx.doi.org/10.1042/bj3250593.
Full textTAMBURRO, Antonio, Nerino ALLOCATI, Michele MASULLI, Domenico ROTILIO, Carmine DI ILIO, and Bartolo FAVALORO. "Bacterial peptide methionine sulphoxide reductase: co-induction with glutathione S-transferase during chemical stress conditions." Biochemical Journal 360, no. 3 (December 10, 2001): 675–81. http://dx.doi.org/10.1042/bj3600675.
Full textHuang, Bixing, Cynthia B. Whitchurch, and John S. Mattick. "FimX, a Multidomain Protein Connecting EnvironmentalSignals to Twitching Motility in Pseudomonasaeruginosa." Journal of Bacteriology 185, no. 24 (December 15, 2003): 7068–76. http://dx.doi.org/10.1128/jb.185.24.7068-7076.2003.
Full textPutra, IGAA, AAAM Adi, and NM Astawa. "Variasi Genetik Gen Penyandi Protein Fusi dari Avian Paramyxovirus Tipe I di Bali (GENETIC VARIATION OF GENE ENCODING FUSION PROTEIN OF AVIAN PARAMYXOVIRUS TYPE-I IN BALI)." Jurnal Veteriner 17, no. 2 (July 15, 2016): 211–17. http://dx.doi.org/10.19087/jveteriner.2016.17.2.211.
Full textXu, Jie, Wu Zhang, Xiaojing Yan, Chen Zhao, Jiang Zhu, Zhu Chen, Sai-Juan Chen, and Jiong Hu. "NPM1 Mutation Contributes to Hematological Dysfunction By Disrupting H3K79 Methylation." Blood 128, no. 22 (December 2, 2016): 2702. http://dx.doi.org/10.1182/blood.v128.22.2702.2702.
Full textMach, Robert L., Clemens K. Peterbauer, Kathrin Payer, Sylvia Jaksits, Sheridan L. Woo, Susanne Zeilinger, Cornelia M. Kullnig, Matteo Lorito, and Christian P. Kubicek. "Expression of Two Major Chitinase Genes of Trichoderma atroviride (T. harzianum P1) Is Triggered by Different Regulatory Signals." Applied and Environmental Microbiology 65, no. 5 (May 1, 1999): 1858–63. http://dx.doi.org/10.1128/aem.65.5.1858-1863.1999.
Full textRejlova, Katerina, Karolina Kramarzova, Meritxell Alberich-Jorda, Karel Fiser, Marketa Zaliova, Jan Trka, and Julia Starkova. "The Role of Histone Demethylases in the Transcription Regulation of HOX Genes in PML-RARa+ AML Patients." Blood 124, no. 21 (December 6, 2014): 876. http://dx.doi.org/10.1182/blood.v124.21.876.876.
Full textDavid Chen, Chun-Wei, Amit U. Sinha, Jun Qi, Aniruddha J. Deshpande, Nan Zhu, Richard Koche, Rowena Eng, et al. "Genome-Wide RNAi Screen Identifies The Mechanistic Role For DOT1L In MLL-Rearranged Leukemia." Blood 122, no. 21 (November 15, 2013): 598. http://dx.doi.org/10.1182/blood.v122.21.598.598.
Full textBearden, Scott W., Teanna M. Staggs, and Robert D. Perry. "An ABC Transporter System of Yersinia pestis Allows Utilization of Chelated Iron by Escherichia coliSAB11." Journal of Bacteriology 180, no. 5 (March 1, 1998): 1135–47. http://dx.doi.org/10.1128/jb.180.5.1135-1147.1998.
Full textKansal, Rita, David A. Rasko, Jason W. Sahl, George P. Munson, Koushik Roy, Qingwei Luo, Alaullah Sheikh, Kurt J. Kuhne, and James M. Fleckenstein. "Transcriptional Modulation of Enterotoxigenic Escherichia coli Virulence Genes in Response to Epithelial Cell Interactions." Infection and Immunity 81, no. 1 (October 31, 2012): 259–70. http://dx.doi.org/10.1128/iai.00919-12.
Full textJo, Stephanie Y., Eric M. Granowicz, and Jay L. Hess. "Assessment of DOT1L as a Therapeutic Target In Acute Leukemia." Blood 116, no. 21 (November 19, 2010): 3291. http://dx.doi.org/10.1182/blood.v116.21.3291.3291.
Full textGrantcharova, Nina, Verena Peters, Claudia Monteiro, Katherina Zakikhany, and Ute Römling. "Bistable Expression of CsgD in Biofilm Development of Salmonella enterica Serovar Typhimurium." Journal of Bacteriology 192, no. 2 (November 6, 2009): 456–66. http://dx.doi.org/10.1128/jb.01826-08.
Full textVilliers, William, Paul Lavender, Audrey Kelly, Michael Lim, Cameron Osborne, and Richard Dillon. "Untangling the Transcriptional Mis-Regulation Driven By Pml;rara." Blood 134, Supplement_1 (November 13, 2019): 282. http://dx.doi.org/10.1182/blood-2019-125555.
Full textIacobucci, Ilaria, Emanuela Ottaviani, Federica Salmi, Viviana Guadagnuolo, Nicoletta Testoni, Annalisa Lonetti, Cristina Papayannidis, et al. "Genome-Wide Analysis by High-Resolution SNP Array Identifies Novel Genomic Alterations in Acute Promyelocytic Leukemia (APL)." Blood 114, no. 22 (November 20, 2009): 167. http://dx.doi.org/10.1182/blood.v114.22.167.167.
Full textStiner, Lawrence, and Larry J. Halverson. "Development and Characterization of a Green Fluorescent Protein-Based Bacterial Biosensor for Bioavailable Toluene and Related Compounds." Applied and Environmental Microbiology 68, no. 4 (April 2002): 1962–71. http://dx.doi.org/10.1128/aem.68.4.1962-1971.2002.
Full textHazim, Antonious Z., Gordon Ruan, Aldo A. Acosta-Medina, Jithma P. Abeykoon, Aishwarya Ravindran, Robert Vassallo, Jay Ryu, et al. "Classical and Non-Classical Phenotypes of Erdheim-Chester Disease: Correlating Clinical, Radiographic, and Genotypic Findings." Blood 138, Supplement 1 (November 5, 2021): 2566. http://dx.doi.org/10.1182/blood-2021-144786.
Full textReisenauer, Mary Rose, Steven W. Wang, Yang Xia, and Wenzheng Zhang. "Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels." American Journal of Physiology-Renal Physiology 299, no. 1 (July 2010): F63—F76. http://dx.doi.org/10.1152/ajprenal.00105.2010.
Full textLibbrecht, Clara, Simone Stefanie Riedel, Jessica Haladyna, and Kathrin M. Bernt. "Menin Is a Therapeutic Target in MN1 High Leukemia." Blood 132, Supplement 1 (November 29, 2018): 758. http://dx.doi.org/10.1182/blood-2018-99-115551.
Full textHoward, Christina, Sergei Zari, Shuangjiang Li, Huang Huang, EunGi Kim, Se Ra Park, Trupta Purohit, et al. "Abstract 3274: Targeting NSD family histone methyltransferase activity with irreversible inhibitors." Cancer Research 82, no. 12_Supplement (June 15, 2022): 3274. http://dx.doi.org/10.1158/1538-7445.am2022-3274.
Full textHarrison, Christine J., Anthony V. Moorman, Claire Schwab, Nyla A. Heerema, Andrew J. Carroll, and Oskar A. Haas. "Intrachromosomal Amplification of Chromosome 21(iAMP21): Cytogenetic Characterisation and Outcome in Childhood B-Cell Precursor Acute Lymphoblastic Leukaemia (BCP-ALL). A Study On Behalf of the Ponte Di Legno International Childhood ALL Workshop." Blood 120, no. 21 (November 16, 2012): 293. http://dx.doi.org/10.1182/blood.v120.21.293.293.
Full textSoverini, Simona, Angela Poerio, Alberto Ferrarini, Ilaria Iacobucci, Marco Sazzini, Joannah Score, Enrico Giacomelli, et al. "Whole-Transcriptome Sequencing In Chronic Myeloid Leukemia Reveals Novel Gene Mutations That May Be Associated with Disease Pathogenesis and Progression." Blood 116, no. 21 (November 19, 2010): 885. http://dx.doi.org/10.1182/blood.v116.21.885.885.
Full textRenzulli, Matteo, C. Terragna, N. Testoni, E. Montanari, P. Tosi, E. Zamagni, P. Tacchetti, et al. "CKS1B Over-Expression Significantly Predicts for a Lower Rate of Response to Primary Therapy with Thalidomide-Dexamethasone (Thali-Dex) for Newly Diagnosed Multiple Myeloma (MM) Patients." Blood 108, no. 11 (November 16, 2006): 371. http://dx.doi.org/10.1182/blood.v108.11.371.371.
Full textIacobucci, Ilaria, Alberto Ferrarini, Marco Sazzini, Enrico Giacomelli, Annalisa Lonetti, Markus Muschen, Luciano Sumerle, et al. "Whole Transcriptome Sequencing of a Philadelphia-Positive Acute Lymphoblastic Leukemia (ALL) with “Next Generation Sequencing” Technology Revealed Novel Point Mutations Associated with Disease-Progression." Blood 114, no. 22 (November 20, 2009): 3074. http://dx.doi.org/10.1182/blood.v114.22.3074.3074.
Full textChu, Yajing, Yangpeng Chen, Huidong Guo, Mengke Li, Jun Shi, Tao Cheng, Feng-Chun Yang, Mingjiang Xu, and Weiping Yuan. "Suv39h1 Represses the Progression of MLL-Rearranged Myeloid Leukemia Via Hoxb13." Blood 132, Supplement 1 (November 29, 2018): 3878. http://dx.doi.org/10.1182/blood-2018-99-113732.
Full textFiskus, Warren, Sunil Sharma, Sunil Abhyankar, Joseph McGuirk, David J. Bearss, and Kapil Bhalla. "Pre-Clinical Efficacy of Combined Therapy with LSD1 Antagonist SP-2509 and Pan-Histone Deacetylase Inhibitor Against AML Blast Progenitor Cells." Blood 120, no. 21 (November 16, 2012): 868. http://dx.doi.org/10.1182/blood.v120.21.868.868.
Full textCole, Christopher B., Angela M. Verdoni, David H. Spencer, and Timothy J. Ley. "Dnmt3a is Required For Aberrant Self-Renewal Driven by PML-RARA." Blood 122, no. 21 (November 15, 2013): 477. http://dx.doi.org/10.1182/blood.v122.21.477.477.
Full textSwords, Ronan T., Aymee Perez, Ana Rodriguez, Justin M. Watts, Fernando Vargas, Roy Elias, Hugh Y. Rienhoff, and Arthur Zelent. "The Small Molecule Img-98, a Potent and Selective Inhibitor of the Lysine Demethylase Lsd-1, Effectively Augments the Pro-Differentiation Effects of ATRA in a Pre-Clinical Model of AML." Blood 126, no. 23 (December 3, 2015): 460. http://dx.doi.org/10.1182/blood.v126.23.460.460.
Full textLynch, James T., Gary J. Spencer, William J. Harris, Alba Maiques-Díaz, Filippo Ciceri, Xu Huang, and Tim C. P. Somervaille. "Pharmacological Inhibitors of LSD1 Promote Differentiation of Myeloid Leukemia Cells through a Mechanism Independent of Histone Demethylation." Blood 124, no. 21 (December 6, 2014): 267. http://dx.doi.org/10.1182/blood.v124.21.267.267.
Full textGhelli Luserna di Rorà, Andrea, Ilaria Iacobucci, Neil Beeharry, Maria Vittoria Falzacappa, Chiara Ronchini, Cristina Papayannidis, Enrica Imbrogno, et al. "Mine the Stability of the G2/M Checkpoint to Break Down Acute Lymphoblastic Leukemia Defenses Against Antineoplastic Drugs." Blood 128, no. 22 (December 2, 2016): 2808. http://dx.doi.org/10.1182/blood.v128.22.2808.2808.
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