Academic literature on the topic 'GC B cell'
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Journal articles on the topic "GC B cell"
Lopez-Ocasio, Maria D. "T Follicular Regulatory (TFR) Cells Regulate B Cell Responses in Both, T-cell Dependent and Independent Pathways." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 48.9. http://dx.doi.org/10.4049/jimmunol.200.supp.48.9.
Full textJones, Derek, Irene Chernova, and David Allman. "B cell-intrinsic mTOR signaling regulates the generation of germinal center B cells (IRM8P.716)." Journal of Immunology 192, no. 1_Supplement (May 1, 2014): 127.17. http://dx.doi.org/10.4049/jimmunol.192.supp.127.17.
Full textSewastianik, Tomasz, Juerg R. Straubhaar, Jian-Jun Zhao, Mehmet K. Samur, Keith Adler, Helen E. Tanton, Vignesh Shanmugam, et al. "miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms." Blood 137, no. 14 (April 8, 2021): 1905–19. http://dx.doi.org/10.1182/blood.2020009088.
Full textLopez-Ocasio, Maria D., and Ethan M. Shevach. "T Follicular Regulatory (TFR) Cells Regulate B Cell Responses By Targeting TF Helper (TFH) Cells." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 223.11. http://dx.doi.org/10.4049/jimmunol.198.supp.223.11.
Full textDing, Chuanlin, and Jun Yan. "Pivotal role of STAT3 signaling in germinal center B cell and T follicular helper cell differentiation (IRC3P.458)." Journal of Immunology 192, no. 1_Supplement (May 1, 2014): 59.1. http://dx.doi.org/10.4049/jimmunol.192.supp.59.1.
Full textBenet, Zachary, Rita Wu, Matangi Marthi, Jackson Turner, and Irina Grigorova. "B cell-intrinsic production of CCL3/4 promotes direct sampling of Germinal Center B cells by T follicular regulatory cells and limits non-foreign antigen specific B cell response." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 195.13. http://dx.doi.org/10.4049/jimmunol.196.supp.195.13.
Full textRea, I. Maeve. "Activated P13Kδ disrupts germinal center GC T(fh)/GC B cell cross talk and B cell antibody coding." Cellular & Molecular Immunology 16, no. 11 (October 8, 2019): 848–50. http://dx.doi.org/10.1038/s41423-019-0295-0.
Full textGrigorova, Irina, and Jackson S. Turner. "Dissecting the contribution of antigen-dependent B cell receptor engagement and T cell help to Germinal Center B cell selection and differentiation." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 107.9. http://dx.doi.org/10.4049/jimmunol.200.supp.107.9.
Full textSaniee, Avva, Kihyuck Kwak, Nicolas Quizon, Haewon Sohn, Javier Manzella-Lapeira, Prasida Holla, Jinghua Lu, et al. "Human germinal center B cells are intrinsically able to discriminate antigen affinity and with T cell help express plasma cell transcription factors." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 107.17. http://dx.doi.org/10.4049/jimmunol.200.supp.107.17.
Full textDe La Pena Enterina, Jhon Ralph, Susmita Sarkar, and Matthew Macauley. "Glycan Remodelling Controls Germinal Centre B cell Responses." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 71.3. http://dx.doi.org/10.4049/jimmunol.204.supp.71.3.
Full textDissertations / Theses on the topic "GC B cell"
Boyden, Alexander Wiser. "Influenza A virus induces regulated T cell-driven B cell responses." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/3432.
Full textMühle, Kerstin. "Interaction of CD8+CD40L+ T cells with B cells." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/19127.
Full textCTLs are important for the elimination of infected and degenerated cells by inducing apoptosis of the target cells. Recently our group identified a sub-population of CD8+ T cells expressing CD40L instead of common CTL markers. To that date, transient CD40L expression on T cells has been only described as a function of activated CD4+ T cells, which displays this key molecule for CD4+ T cell mediated help by binding to the CD40 receptor on other immune cells. Particularly, CD40L signaling provided by CD4+ T cells is indispensable for T cell dependent B cell activation and GC responses, which generate B cells secreting high affinity antibodies that protect the host from invading pathogens. Due to its associated helper functions, this thesis aimed to dissect whether CD40L positive CD8+ T cells are restricted to cytotoxic killing or if this sub-population possesses similar properties as CD4+ T cells when interacting with B cells. In vitro co-culture experiments showed that 50% of murine antigen specific CD8+ T cells up-regulated CD40L upon activation by antigen presenting B cells. When compared to CD40L deficient CD8+ T cells, the interaction of CD8+ CD40L+ T cells induced remarkable changes in B cells on the RNA and protein level and triggered a B cell phenotype resembling that of B cells primed by CD4+ T cells. By the infection of mice with the B cell trophic virus MHV-68, it was found that E8IcrexCD40Lflox transgenic mice lacking CD40L only on matured CD8+ T cells, exhibited a significant decrease of GC B cells in superficial cervical lymph nodes at the acute state of infection compared to WT mice. A closer look into the memory B cell repertoire revealed a preferred usage of the murine IGHJ3 gene family that modifies the CDR3 and thus the recognition groove of the B cell antibody in E8IcrexCD40Lflox mice. In summary, this work provides sufficient evidence that CD8+ CD40L+ T cells adopt helper-like functions by supporting B cell activation and subsequent GC formation.
Weisenburger, Thomas [Verfasser], Thomas H. [Akademischer Betreuer] Winkler, Thomas H. [Gutachter] Winkler, and David [Gutachter] Vöhringer. "The role of Fas (CD95) for positive selection of GC B cells / Thomas Weisenburger ; Gutachter: Thomas H. Winkler, David Vöhringer ; Betreuer: Thomas H. Winkler." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2020. http://d-nb.info/1216704309/34.
Full textPratama, Alvin. "Post-transcriptional control of T follicular helper cells." Phd thesis, 2015. http://hdl.handle.net/1885/13828.
Full textMärz, Sabine. "Regulation of fungal polar tip extension through NDR kinase signalling." Doctoral thesis, 2009. http://hdl.handle.net/11858/00-1735-0000-0006-ADB2-B.
Full textBook chapters on the topic "GC B cell"
Chu, Van Trung, Robin Graf, and Klaus Rajewsky. "CRISPR/Cas9-Mediated In Vitro Mutagenesis in GC-Like B Cells." In Methods in Molecular Biology, 135–45. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7095-7_12.
Full text"GC/Post-GC Type B-Cell Tumors." In Encyclopedia of Cancer, 1515. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_2345.
Full textConference papers on the topic "GC B cell"
Ishii, Hiroyuki, Yoshihisa Kishiyama, and Hideaki Takahashi. "A novel architecture for LTE-B :C-plane/U-plane split and Phantom Cell concept." In 2012 IEEE Globecom Workshops (GC Wkshps). IEEE, 2012. http://dx.doi.org/10.1109/glocomw.2012.6477646.
Full textRuiz-Justiz, Armando J., Mona Yazdani, Xin Sun, Lili Chen, Michael Wang, John Le, Haiping Guo, et al. "Characterization of T/B cell antigen specific-engineered tumors for studying T cell and GC B cell function in a murine model of NSCLC." In Leading Edge of Cancer Research Symposium. The University of Texas at MD Anderson Cancer Center, 2022. http://dx.doi.org/10.52519/00080.
Full textZhang, Jiyuan, David Dominguez-Sola, Shafinaz Hussein, Ji-Eun Lee, Antony B. Holmes, Mukesh Bansal, Sofija Vlasevska, et al. "Abstract B25: Disruption of KMT2D-dependent histone methylation perturbs GC B cell development and cooperates with BCL2 deregulation in lymphomagenesis." In Abstracts: AACR Special Conference: Chromatin and Epigenetics in Cancer; September 24-27, 2015; Atlanta, GA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.chromepi15-b25.
Full textChen, Kok Hao, and Jong Hyun Choi. "Nanoparticle-Aptamer: An Effective Growth Inhibitor for Human Cancer Cells." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-11966.
Full textLevels, MJ, CM Fehres, NOP Van Uden, AQ Bakker, H. Spits, DL Baeten, and NG Yeremenko. "P035 The transcriptional co-activator bob.1 prevents terminal differentiation and induces costimulatory capacity of B cells in GC-like environment." In 38th European Workshop for Rheumatology Research, 22–24 February 2018, Geneva, Switzerland. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-ewrr2018.57.
Full textMazumdar, Darshana. "Association of organochlorine pesticides and risk of epithelial ovarian cancer: A case control study." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685303.
Full textReports on the topic "GC B cell"
Yalovsky, Shaul, and Julian Schroeder. The function of protein farnesylation in early events of ABA signal transduction in stomatal guard cells of Arabidopsis. United States Department of Agriculture, January 2002. http://dx.doi.org/10.32747/2002.7695873.bard.
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