Academic literature on the topic 'GBV screening'
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Journal articles on the topic "GBV screening"
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Watanabe, Maria Angelica Ehara, Ana Karina Melim Benthien Miquelão, Carlos Eduardo Coral de Oliveira, Karen Brajão de Oliveira, Thiago Franco Nasser, Mateus Nóbrega Aoki, Patrícia Sayuri Suzuki, Marla Karine Amarante, Emerson José Venâncio, and Elbens Marcos Minoreli de Azevedo. "Detection of GBV-C/HGV RNA in cervico-vaginal smears from healthy individuals." Brazilian Archives of Biology and Technology 51, no. 5 (October 2008): 917–22. http://dx.doi.org/10.1590/s1516-89132008000500007.
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The purpose of the present study was to evaluate the sexual transmission of GBV-C/HGV, through RNA detection in cervicovaginal smears. Therefore the GBV-C/HGV RNA in cervicovaginal smears from apparently healthy women was investigated using routine proceedings for prophylactic screening to cervical cancer. GBV-C/HGV RNA was detected by reverse transcriptase and polymerase chain reaction (RT-PCR). Only one woman presented co-infection with human papilloma virus (HPV). The GBV-C/HGV RNA was detected in 13/73 (17.57%) healthy women and it's prevalence in participating women between 28-43 years old was 53.85%. No association was found with GBV-C/HGV for the age of first sexual intercourse and number of pregnancies. In GBV-C/HGV RNA positive women, 69.23% were married. In conclusion, the present findings show that cervical and vaginal specimens could contain the GBV-C/HGV RNA.
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Bally, Cyrus Ashivira, Proscovia Adema, Kennedy Situma, Samuel Musau, Roberts Osangale, and Grace Kibet. "ENORMITY AND PATTERNS OF GENDER BASED VIOLENCE AT KENYA MEDICAL TRAINING COLLEGE CAMPUSES." International Journal of Health Sciences 5, no. 1 (July 19, 2022): 33–51. http://dx.doi.org/10.47941/ijhs.933.
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Purpose: To unravel the socio-demographic factors, assess knowledge, awareness and institutional factors that are associated with gender based violence at KMTC campuses.
Methodology: A semi structured questionnaire was utilized to conduct a cross-sectional descriptive study of 302 participants, yielding to 300 responses.
Findings: The study findings divulged that (81) 27% of 302 participants had experienced Gender Based Violence (GBV) at the institution and its community. Majority of the respondents were aged 31 years and above. The predictors of GBV at KMTC among staff with statistically significance were: Level of education (χ2 (df=4) =72.54, p=0.01), the type of GBV especially sexual and economic abuse (χ2 (df=4) =72.57, p=0.00), lack of GBV policy in place and lack of GBV recovery centres p=0.00 respectively. In conclusion level of education, the type of GBV, lack of GBV policy in place and lack of GBV recovery centres were pin pointed as the most imperative prognosticators that were associated with GBV.
Unique contribution of theory, practice and policy: The study recommends KMTC as a government institution to strengthen the policies already in use about GBV at the college, to health educate its staff about GBV especially sexual and physical abuse via workshops and seminars, to set up GBV recovery centres in every region of Kenya in the respective major campuses and employ qualified staff who can be able to provide GBV services such as counselling, screening and treatment to its staff, students and community at large.
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Aryal, Shreyashi, Sagun B. Pant, and Sebina Baniya. "Gender-based Violence in Women attending Gynecology Outpatient Department in a Hospital of Western Nepal: An Issue of Endurance and Invisibility." Journal of South Asian Federation of Obstetrics and Gynaecology 9, no. 3 (August 2017): 225–29. http://dx.doi.org/10.5005/jp-journals-10006-1500.
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ABSTRACT Introduction Gender-based violence (GBV) is faced by many women in Nepal but health-seeking behavior is rare. A reproductive health facility may be the only place where a woman comes for a health visit. So, health care providers, especially gynecologists, play an important role to identify women suffering from GBV as they see clients suffering from the reproductive health effects of GBV on a daily basis. The purpose of this study was to find the prevalence and severity of GBV in women attending the outpatient department (OPD) and to compare their clinical diagnosis with those not facing GBV. Materials and methods This is a prospective study conducted at Lumbini Medical College Teaching Hospital for a period of 3 months enrolling 741 nonpregnant women attending the OPD. A structured questionnaire was used for interview to identify women facing abuse and to assess their gynecological problems. Results Out of 741 women, 172 faced GBV, so the prevalence was 23.21%. Emotional and physical abuse was the most common type of abuse faced by 56 (32.56%), but the severity was reported more in sexual abuse [8 (57.14%)]. Pain abdomen was the most common symptom [69 (40.12%)], and chronic pelvic pain (CPP) [60 (34.89%)] was the commonest clinical diagnosis made in these women. Chronic pelvic pain was diagnosed more in women facing abuse (p < 0.001). Conclusion In this study, about one in four women in reproductive age group had experienced GBV. Gynecology OPD of a tertiary hospital could be used as a screening setting that can assist in early detection and prevention of GBV in Nepal. How to cite this article Aryal S, Pant SB, Baniya S. Gender-based Violence in Women attending Gynecology Outpatient Department in a Hospital of Western Nepal: An Issue of Endurance and Invisibility. J South Asian Feder Obst Gynae 2017;9(3):225-229.
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Yalcinoz-Ucan, Busra, Laura Zilney, Agnes Zientarska-Kayko, Timothy Ireland, and Dillon Thomas Browne. "Examining the effectiveness of psychological interventions for marginalised and disadvantaged women and individuals who have experienced gender-based violence: protocol for a scoping review." BMJ Open 12, no. 7 (July 2022): e060479. http://dx.doi.org/10.1136/bmjopen-2021-060479.
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IntroductionExposure to gender-based violence (GBV) has devastating psychological outcomes for victims/survivors. Particularly in conditions where GBV intersects with multiple forms of oppression, the negative impacts of violence are more challenging to overcome and potential pathways for recovery become less accessible. However, evidence regarding the availability and effectiveness of mental health interventions for GBV survivors from marginalised and disadvantaged communities has yet to be systematically integrated and synthesised. The proposed scoping review will examine the relevant literature regarding the availability and effectiveness of psychological interventions for survivors of GBV from marginalised and disadvantaged backgrounds. This review will (i) document what psychological interventions have been available and empirically established for marginalised and disadvantaged women and individuals with experiences of GBV, (ii) provide a narrative examination of the treatment outcomes of identified interventions regarding their effectiveness and (iii) examine the degree to which GBV interventions in selected sources are designed and applied with a recognition of the social determinants of mental health.Methods and analysisThe search for the proposed scoping review will include five electronic databases: PsycINFO, Scopus, Web of Science, Ovid Medline, and CINAHL. The database search will be completed in June 2022. An additional search will be conducted before the completion of the study in December 2022. The search will target research studies published after 2010. The primary eligibility criterion for study selection is having a focus on psychological interventions for GBV survivors from marginalised and disadvantaged groups. Two reviewers will conduct screening and data extraction. The data will be evaluated to map the treatment outcomes of interventions and their effectiveness. Implications for clinical services will be discussed.Ethics and disseminationNo ethical consideration is foreseen for this scoping review. The dissemination will be done through a publication in a top-tier open access journal and conference presentations.
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Decker, Michele R., Carrie Lyons, Kathleen Guan, Vanessa Mosenge, Ghislane Fouda, Daniel Levitt, Anna Abelson, et al. "A Systematic Review of Gender-Based Violence Prevention and Response Interventions for HIV Key Populations: Female Sex Workers, Men Who Have Sex With Men, and People Who Inject Drugs." Trauma, Violence, & Abuse 23, no. 2 (February 11, 2022): 676–94. http://dx.doi.org/10.1177/15248380211029405.
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Gender-based violence (GBV) is that perpetrated based on sex, gender identity, or perceived adherence to socially defined gender norms. This human rights violation is disproportionately experienced by HIV key populations including female sex workers (FSW), people who inject drugs (PWID), and men who have sex with men (MSM). Consequently, addressing GBV is a global priority in HIV response. There is limited consensus about optimal interventions and little known about effectiveness. Our systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was registered in International Prospective Register of Systematic Reviews. Peer-reviewed and non-peer-reviewed literature were searched for articles that described a GBV prevention or response intervention specifically for key populations including FSW, PWID, and MSM. Results were organized by level(s) of implementation and pillars of a comprehensive GBV response: prevention, survivor support, and accountability/justice. Of 4,287 articles following removal of duplicates, 32 unique interventions (21 FSW, seven PWID, and nine MSM, not mutually exclusive) met inclusion criteria, representing 13 countries. Multisectoral interventions blended empowerment, advocacy, and crisis response with reductions in violence. Individual-level interventions included violence screening and response services. Violence-related safety promotion and risk reduction counseling within HIV risk reduction programming reduced violence. Quantitative evaluations were limited. Violence prevention and response interventions for FSW, PWID, and MSM span individual, community, and multisectoral levels with evidence of promising practices at each level. The strongest evidence supported addressing violence in the context of sexually transmitted infection/HIV risk reduction. As interventions continue to emerge, the rigor of accompanying evaluations must simultaneously advance to enable clarity on the health and safety impact of GBV prevention and response programming.
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Keys, Jessica R., Peter A. Leone, Joseph J. Eron, Kelcie Alexander, Myra Brinson, and Ronald Swanstrom. "Large scale screening of human sera for HCV RNA and GBV-C RNA." Journal of Medical Virology 86, no. 3 (October 31, 2013): 473–77. http://dx.doi.org/10.1002/jmv.23829.
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Wijegunasekara, JLHR, and KDP Wijesinghe. "Health Sector Interventions to address Gender Based Violence: in Sri Lanka." Journal of Medical Research 6, no. 5 (October 28, 2020): 246–48. http://dx.doi.org/10.31254/jmr.2020.6515.
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Gender Based Violence (GBV) is a common form of violence globally and includes physical, sexual, emotional and economic violence. GBV has serious consequences for women’s health and well-being and takes a high national cost for the treatment and rehabilitation. Prevalence of GBV is usually underestimated. GBV is addressed globally using good practices in justice, health, education and multi- sector. Health sector is in a valuable position to support survivors and change social attitudes. Interventions taken in the health sector should be targeted at all three levels; primary prevention, secondary prevention and tertiary prevention. There are different models used in health care settings in different countries. “Mithuru Piyasa (in Sinhalese) / Natpu Nilayam (in Tamil)” which is staffed with a medical officer and a nursing officer was introduced in Sri Lanka as a “One Stop Crisis Centre/One Stop Service Centre” for survivors within the health institutions. Its main functions are screening, medical care, befriending services, risk assessment and safety planning, referral to legal, social, counseling and rehabilitation services, advocacy and community mobilization. Services are provided adhering to its guiding principles of safety, confidentiality, respect, non - discrimination, responsibility, competence and compassion. Documentation, Information management, progress review and evaluation are carried out for the sustainability of the service. Still this opportunity is not fully utilized. Service provision is not uniform in quality, coverage, equity, efficiency and effectiveness. Administrators are expected to develop their interest and pay their attention with priority, in supporting the functioning of these centres established under outpatient department by proper operation, expanding country wide and marketing.
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Valentine Chidi Obidile, Antor Odu Ndep, Onyeka Chukwudalu Ekwebene, Chidozie Precious Azubike, Lois Ezinne Obidile-Ikwegbu, Ray-Desmond Umechinedu, and Charles Nnamdi Ezeaka. "Post gender-based violence care, support services and health outcomes among victims of gender-based violence in Akwa Ibom and Cross-River States Nigeria." International Journal of Science and Research Archive 6, no. 2 (July 30, 2022): 006–15. http://dx.doi.org/10.30574/ijsra.2022.6.2.0138.
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Background: Gender-based violence has a negative impact on the physical and mental health of the victim, especially younger adults. Methodology: This cross-sectional descriptive study was carried out in Cross River and Akwa Ibom States of Nigeria using both qualitative and quantitative approaches. The study population comprised young adults aged 15-39 years in Cross River and Akwa Ibom States. The principal researcher and three field assistants administered 426 copies of the questionnaire to respondents. The data were analyzed using Statistical Packages for the Social Sciences software (SPSS) version 22. Thematic analysis was used for the qualitative data. Results: The majority of respondents 346(83.8%) knew that gender-based violence affects the health and wellbeing of victims; there were 267(64.6%) young adults who identified that gender-based violence poses both long-term and short-term effects on the health of the victims with 198(47.9%) who have suffered at least, one form of gender-based violence. Shame, (32.7%), anger, (27.8%), Bruises/injuries (25.2%) and low self-esteem (22.5) were the most frequently reported physical and emotional health effects of GBV. Many do not seek care due to shame. For those who sought care, counseling 97(49%), HIV/AIDS counselling and screening 66 (33.3%), STI screening 52(26.2%), and oral pills 24(12.2%) were some of the services accessed by victims. Discussion: This finding is consistent with reports from other GBV studies whose respondents suffered depression (48.8%), fear and anxiety (31.0%), which they argued were more serious conditions than the physical health impact of gender-based violence. Mental and emotional health outcomes of GBV are mostly invisible to others, making it harder for victims to seek help. Conclusion: Gender-based violence has negative impact on the physical and mental health of the victim, especially younger adults.
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Nordbø, Svein Arne, Sidsel Krokstad, Per Winge, Finn Egil Skjeldestad, and Are B. Dalen. "Prevalence of GB Virus C (Also Called Hepatitis G Virus) Markers in Norwegian Blood Donors." Journal of Clinical Microbiology 38, no. 7 (2000): 2584–90. http://dx.doi.org/10.1128/jcm.38.7.2584-2590.2000.
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GB virus C (GBV-C), also called hepatitis G virus (HGV), occurs worldwide, but the clinical significance of this virus is still unclear. Plasma samples from 1,001 blood donors were tested by reverse transcription PCR using primers from the NS5 region and by a commercial enzyme-linked immunosorbent assay (ELISA) for the detection of immunoglobulin G antibodies against the putative envelope of HGV (anti-HGV E2). GBV-C/HGV RNA was present in the plasma from 2.5% of the blood donors, and anti-HGV E2 antibodies could be detected in 10.5% of the samples. Only one of the blood donors with viremia had elevated levels of alanine aminotransferase. Among ELISA-positive donors, there was a significantly higher percentage (16.5%) of individuals who had been treated by acupuncture than individuals who had not been given this treatment (9.4%). No other variables showed significant differences. Screening of medical records from 401 recipients of blood from PCR-positive donors revealed no association with liver disease. Four of 12 partners (33%) were HGV RNA positive, and sequence analyses of the strains showed that four of the couples probably were infected with the same strains, while strains from different couples were not identical. Anti-HGV E2 antibodies were detected in serum samples from four other partners. The prevalence of GBV-C/HGV among blood donors in our region is dramatically higher than the prevalence of hepatitis C virus (0.03%).
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Schuler, Sidney Ruth, Quach Thu Trang, Vu Song Ha, and Hoang Tu Anh. "Qualitative Study of an Operations Research Project to Engage Abused Women, Health Providers, and Communities in Responding to Gender-Based Violence in Vietnam." Violence Against Women 17, no. 11 (November 2011): 1421–41. http://dx.doi.org/10.1177/1077801211433990.
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This article describes an action research project designed to engage women, health providers, and communities to respond to gender-based violence (GBV) in Vietnam. Based on results from in-depth interviews and group discussions, it considers the extent to which the project approaches were empowering for abused women. The results underscore the problems entailed in introducing systematic screening for gender-based violence into government health facilities in the low-resource setting of Vietnam, the importance of combining ideational change and rights components with support for abused women, and the difficulty of engaging male perpetrators.
Dissertations / Theses on the topic "GBV screening"
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Bergseng, Håkon. "Aspects of Group B streptococcus(GBS) disease in the newborn : Epidemiology, characterisation of invasive strains and evaluation of intrapartum screening." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for laboratoriemedisin, barne- og kvinnesykdommer, 2009. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-5527.
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Kilimann, Stephanie. "Pharmakogenetisches Screening bei Erstdiagnose einer Schizophrenie: Existiert hinsichtlich der Leistungserstattung ein gesundheitsökonomischer Nutzen seitens der GKV? - Entwicklung eines gesundheitsökonomischen Evaluationskonzepts." Master's thesis, Dresden International University, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-133079.
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Ziel: Entwicklung eines gesundheitsökonomischen Evaluationskonzepts zum Nachweis einer Kostenreduktion unter gleichzeitiger Optimierung des medizinischen Nutzens durch pharmakogenetisches Screening bei Erstdiagnose einer Schizophrenie. Finale Zielsetzung ist die Aufnahme der pharmakogenetischen a priori-Diagnostik für die Indikation Schizophrenie in die GKV-Regelversorgung. Methodik: Basierend auf dem aktuellen Stand gendiagnostischer Forschung sowie der evidenzbasierten Schizophrenietherapie wurde eine prospektive, randomisierte und kontrollierte, dreiarmige, offene, multizentrische Pilotstudie im Paralleldesign über 3 Jahre konzeptioniert. Studienpopulation: 300 Patienten (1:1:1) im Alter von 18 bis 65 Jahren mit erstmaliger F20-Diagnose (ICD-10). Interventionen: pharmakogenetisches Screening und integrierte Versorgung; integrierte Versorgung; Standardversorgung. Die Erhebung des medizinischen Nutzens erfolgt durch Messung des klinischen Outcome bzgl. der patientenrelevanten Endpunkte Mortalität, Morbidität, Lebensqualität und Nebenwirkungen zu definierten Zeitpunkten. Perspektivisch relevante Kosten werden im "piggy back"-Verfahren ermittelt. Ergebnisse: Angesichts zurzeit bestehender Limitationen im deutschen Gesundheitssystem (z.B. unzureichendes intersektorales Schnittstellenmanagement bei der Arzneimittelversorgung und Informationsweitergabe) wird die Integrierte Versorgung als geeignete Versorgungsform für den Nutzennachweis eingestuft. Die Integrierte Versorgung stellt jedoch momentan nicht den allgemeinen Standard der psychiatrischen Patientenversorgung dar. Aus GKV-Perspektive wesentliche Kostentreiber der Schizophrenietherapie sind Rückfälle, Krankenhausaufenthalte, Arbeitslosigkeit und vorzeitige Verrentung. Eine Verringerung der Häufigkeit dieser Parameter könnte z.B. zu einer Reduktion der Erstjahres-Behandlungskosten (zurzeit ca. 30% der Gesamtkosten) führen. Die Kosten-Effektivitäts-Analyse erweist sich als Studienform mit der geringsten Anfälligkeit für Bias und Confounder. Trotz einer vergleichsweise hohen externen Validität ist das Studiensetting nicht uneingeschränkt übertragbar auf die Versorgungsrealität des deutschen Gesundheitssystems. Es existiert aktuell keine generelle Empfehlung für den Einsatz der Gendiagnostik zur Steuerung der Arzneimitteltherapie in Psychiatrie. Ebenso hat die integrierte Versorgung bisher keinen umfassenden Einzug in den psychiatrischen Behandlungsalltag gefunden, so dass die beschriebenen Limitationen einen positiven Nutzennachweis erschweren. Dennoch ist das Konzept als praktisch umsetzbar zu bewerten. Schlussfolgerung: Bei dieser Faktenlage ist das Interesse der GKV an der Veranlassung einer gesundheitsökonomischen Evaluation mit dem Ziel einer Erstattungsfähigkeit des a priori durchgeführten pharmakogenetischen Screenings bei Schizophrenie als eher gering einzustufen. Jedoch lassen das Update der S3-Praxisleitlinie mit dem Einbezug der strukturierten u. integrierten Versorgung sowie der Aktionsplan „Individualisierte Medizin“ des Bundesforschungsministeriums auf eine Fokussierung auf diese Fragestellung und veränderte Interessenlage bzgl. der Initiierung der Pilotstudie hoffen. Weitere Forschungstätigkeit sowie die praktische Erprobung neuer gendiagnostischen Verfahren sind, basierend auf versorgungsbezogenen Pilotstudien wie der hier konzeptionierten, fachübergreifend erforderlich, um die Relevanz der Methodik für den psychiatrischen Versorgungsalltag zu belegenPurpose: Development of a health-economic investigation method to study whether a cost reduction under concurrent optimisation of the medical use exists by using pharmacogenetic a- priori- screening with first diagnosis of a schizophrenia. Final objective is the reimbursement of pharmacogenetic diagnostics for the indication schizophrenia in the German health statutory insurance (GKV). Methods: A prospective, randomised and controlled, 3-armed, parallel, open, multicentre pilot study with a duration of 3 years was designed based on the actual status of genetic-diagnostic research as well as the evidence-based therapy of schizophrenia. Study population: 300 patients (1:1:1) aged 18 to 65 years with initial F20 diagnosis (ICD-10). Interventions: pharmacogenetic screening and integrated care; integrated care; standard care. For evaluation of the medical benefit the clinical outcome is measured at defined times with regard to the patients' relevant endpoints mortality, morbidity, quality of life and side effects. In perspective relevant costs are determined by "piggy back" procedure. Results: In view of actually existing limitations within the German health system (e.g., insufficient intersectional medication and information management) the integrated care is considered being a suitable setting to demonstrate the advantage of using pharmacogenetic screening. Nevertheless, the integrated care does not show the general standard of the psychiatric patient's care at the moment. From GKV perspective essential cost drivers of schizophrenia therapy are relapses, hospital stays, unemployment and untimely superannuation. Diminishing the rate of these parametres could lead, e.g., to a reduction of the first year medical costs (at the moment approx. 30% of the total expenses). The cost-effectiveness analysis seems to be the study form with the slightest susceptibility to bias and confounding. In spite of a relatively high external validity the study setting is not unconditionally transferable to the German health system. Currently no general recommendation exists for the application of the genetic diagnostics to manage medication therapy in psychiatry. Up to now also the integrated care has not found a comprehensive entry in psychiatric practice, so that the described limitations are complicating a positive use proof. Nevertheless, the investigational concept can be regarded as feasible. Conclusion: Based on the existing situation the GKV's interest in performing a health-economic evaluation, which is focussed on the reimbursement of pharmacogenetic a priori-diagnostics in schizophrenia, is considered to be low. However, the situation may change in view of the expected update of the S3-practise guideline with the focus on structured and integrated care as well as the action plan „individualised medicine“ of the German federal research ministry. Thus, there is hope for changing interests in a pilot study. Based on care-related pilot studies as presented here, further research activities and practical testing of recent gene diagnostic procedures are necessary to demonstrate the relevance of the methodology for psychiatric practice
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Dantas, Hebertty Vieira. "Triagem da qualidade de amostras de GNV e GLP usando espectrometria NIR e quimiometria." Universidade Federal da Paraíba, 2010. http://tede.biblioteca.ufpb.br:8080/handle/tede/7186.
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Previous issue date: 2010-10-10Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
The search for new energy sources and concern about environmental problems has caused an increase in the use of gaseous fuels like natural gas (CNG) and liquefied petroleum gas (LPG). The main advantages of these fuels besides clean energy, are low production and processing costs, high efficiency and versatility. Given these realities, there is both growing need and demand for quality controls applicable to these types of fuel. This study proposes quality screening analysis of gaseous fuels using near infrared (NIR) absorption spectroscopy for verifying adulteration and/or nonconformity of LPG and CNG samples. The development of gas handling equipment made possible the construction of different classification models for screening analysis, such as SIMCA, SPA-SPA-LDA and SIMCA. To build and test these models, several samples were grouped as; tampered with, adulterated, and commercially certified standard. The results demonstrated the methodology as effective and robust for performing preliminary analysis of CNG and LPG quality, minimizing normal drawbacks of the quality control reference methods used for these fuels.
A busca por novas fontes de energia e a preocupação com problemas ambientais provocaram um aumento no uso de combustíveis gasosos como o gás natural veicular (GNV) e gás liquefeito de petróleo (GLP). Entre as principais vantagens desses combustíveis, destacam-se o baixo custo de produção e processamento, sua grande eficiência e versatilidade, além de ser uma fonte limpa de energia. Diante dessa realidade, cresce também a necessidade e a demanda pelo monitoramento da qualidade e fiscalização desse tipo de combustível. Esse trabalho propõe a utilização da análise de triagem da qualidade dos combustíveis gasosos por espectroscopia de absorção no infravermelho próximo (NIR) para verificação de adulterações ou nãoconformidades de amostras de GLP e GNV. O desenvolvimento de equipamentos de manipulação de gases possibilitou a construção de diferentes modelos de classificação para análise de triagem, tais como, SIMCA, SPA-LDA e o SPASIMCA. Para construir e testar esses modelos, foram agrupadas diversas amostras adulteradas, não-adulteradas e padrões certificados comercialmente. Os resultados demonstraram que a metodologia desenvolvida é bastante eficaz e robusta ao realizar análises preliminares da qualidade do GNV e GLP, minimizando alguns inconvenientes dos métodos de referência utilizados para o controle de qualidade desses combustíveis.
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Dantas, Hebertty Vieira. "Um sistema em fluxo para preparação de misturas gasosas e análise screening de GNV e GLP com respeito ao conteúdo de metano e propano usando espectrometria NIR e quimiometria." Universidade Federal da Paraíba, 2014. http://tede.biblioteca.ufpb.br:8080/handle/tede/7147.
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Previous issue date: 2014-06-02Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
Concern about environmental problems triggered the search for new sources of energy and consequently caused an increase in the use of gaseous fuels such as natural gas (NG) and liquefied petroleum gas (LPG). Given this reality, there is growing demand for quality monitoring and supervision of this type of fuel. This paper proposes a flow system for the screening of samples of LPG and NG by near infrared spectrometry (NIR) analysis in order to verify the quality of these fuels in relation to its major concentration of hydrocarbons, propane and methane, respectively. For this, one spectrophotometric flow cell for gas, seven NG containers collectors and one flow system for injection and mixture of gases, as well as its automation (SAIMG) and building management software (GasMixer) were developed. The gas handling equipment and systems for flow enabled the development of SPA-LDA and SIMCA models for screening analysis of samples of LPG and NG. The classification models were constructed and tested with commercial samples that have been previously grouped and analyzed by gas chromatography. Adulterated NG mixtures with nitrogen, compressed air, ethane and lighter fluid were also created. LPG samples were grouped into two different classes depending on the concentration of propane, which have been termed "rich LPG" and "poor LPG" The NG samples were analyzed according to the specified limit for the concentration of methane, which resulted in negative cases ( NG -) and positive (NG +) when they are considered respectively higher or lower than the limits set limit. The results showed that the screening analysis was efficient and robust, reaching 100% accuracy compared samples of LPG and NG test. In addition, the automation of the flow system optimizes all stages of the analysis and enhances their use in future applications
A preocupação com os problemas ambientais impulsionaram a busca por novas fontes de energia e consequentemente provocaram um aumento no uso de combustíveis gasosos como o gás natural veicular (GNV) e gás liquefeito de petróleo (GLP). Diante dessa realidade, cresce também a demanda pelo monitoramento da qualidade e fiscalização desse tipo de combustível. Esse trabalho propõe um sistema em fluxo para a análise screening de amostras de GLP e GNV através da espectrometria no infravermelho próximo (NIR), a fim de verificar a qualidade desses combustíveis em relação a concentração de seus hidrocarbonetos majoritários, o propano e o metano, respectivamente. Para tanto, foram desenvolvidos uma célula espectrofotométrica de fluxo para gás, sete recipientes coletores de GNV e um sistema em fluxo para introdução e mistura de gases, bem como sua automação (SAIMG) e criação de um software de gerenciamento (GasMixer). Os equipamentos de manipulação gasosa e o sistemas em fluxo possibilitaram o desenvolvimento dos modelos SIMCA e SPA-LDA para análise screening de amostras de GLP e GNV. Os modelos de classificação foram construidos e testados com amostras comerciais que foram agrupadas e analisadas previamente por cromatografia gasosa. Também foram criadas misturas adulteradas de GNV com nitrogênio, ar comprimido, etano e fluido de isqueiro. As amostras de GLP foram agrupadas em duas classes distintas em função da concentração de propano, as quais foram denominadas GLP rico e GLP pobre . As amostras de GNV foram analisadas de acordo com o limite especificado para a concentração de metano, o que resultou em casos negativos (GNV !) e positivos (GNV +) quando são considerados respectivamente superiores ou inferiores aos limites estabelecidos. Os resultados demonstraram que a análise screening foi eficaz e robusta, alcançando 100% de acerto em relação as amostras de teste de GLP e GNV. Além disso, a automação do sistema em fluxo otimiza todas as etapas da análise e potencializa seu uso em aplicações futuras.
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Bray, B. A., I. C. Sutcliffe, and Dean J. Harrington. "Impact of lgt mutation on lipoprotein biosynthesis and in vitro phenotypes of Streptococcus agalactiae." 2009. http://hdl.handle.net/10454/11570.
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NoAlthough Streptococcus agalactiae, the group B Streptococcus, is a leading cause of invasive neonatal disease worldwide the molecular basis of its virulence is still poorly understood. To investigate the role of lipoproteins in the physiology and interaction of this pathogen with host cells, we generated a mutant S. agalactiae strain (A909DeltaLgt) deficient in the Lgt enzyme and thus unable to lipidate lipoprotein precursors (pro-lipoproteins). The loss of pro-lipoprotein lipidation did not affect the viability of S. agalactiae or its growth in several different media, including cation-depleted media. The processing of two well-characterized lipoproteins, but not a non-lipoprotein, was clearly shown to be aberrant in A909DeltaLgt. The mutant strain was shown to be more sensitive to oxidative stress in vitro although the molecular basis of this increased sensitivity was not apparent. The inactivation of Lgt also resulted in changes to the bacterial cell envelope, as demonstrated by reduced retention of both the group B carbohydrate and the polysaccharide capsule and a statistically significant reduction (P=0.0079) in A909DeltaLgt adherence to human endothelial cells of fetal origin. These data confirm that failure to process lipoproteins correctly has pleiotropic effects that may be of significance to S. agalactiae colonization and pathogenesis.
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Kilimann, Stephanie. "Pharmakogenetisches Screening bei Erstdiagnose einer Schizophrenie: Existiert hinsichtlich der Leistungserstattung ein gesundheitsökonomischer Nutzen seitens der GKV? - Entwicklung eines gesundheitsökonomischen Evaluationskonzepts." Master's thesis, 2013. https://diu.qucosa.de/id/qucosa%3A21569.
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Ziel:
Entwicklung eines gesundheitsökonomischen Evaluationskonzepts zum Nachweis einer Kostenreduktion unter gleichzeitiger Optimierung des medizinischen Nutzens durch pharmakogenetisches Screening bei Erstdiagnose einer Schizophrenie. Finale Zielsetzung ist die Aufnahme der pharmakogenetischen a priori-Diagnostik für die Indikation Schizophrenie in die GKV-Regelversorgung.
Methodik:
Basierend auf dem aktuellen Stand gendiagnostischer Forschung sowie der evidenzbasierten Schizophrenietherapie wurde eine prospektive, randomisierte und kontrollierte, dreiarmige, offene, multizentrische Pilotstudie im Paralleldesign über 3 Jahre konzeptioniert.
Studienpopulation: 300 Patienten (1:1:1) im Alter von 18 bis 65 Jahren mit erstmaliger F20-Diagnose (ICD-10).
Interventionen: pharmakogenetisches Screening und integrierte Versorgung; integrierte Versorgung; Standardversorgung.
Die Erhebung des medizinischen Nutzens erfolgt durch Messung des klinischen Outcome bzgl. der patientenrelevanten Endpunkte Mortalität, Morbidität, Lebensqualität und Nebenwirkungen zu definierten Zeitpunkten. Perspektivisch relevante Kosten werden im "piggy back"-Verfahren ermittelt.
Ergebnisse:
Angesichts zurzeit bestehender Limitationen im deutschen Gesundheitssystem (z.B. unzureichendes intersektorales Schnittstellenmanagement bei der Arzneimittelversorgung und Informationsweitergabe) wird die Integrierte Versorgung als geeignete Versorgungsform für den Nutzennachweis eingestuft. Die Integrierte Versorgung stellt jedoch momentan nicht den allgemeinen Standard der psychiatrischen Patientenversorgung dar. Aus GKV-Perspektive wesentliche Kostentreiber der Schizophrenietherapie sind Rückfälle, Krankenhausaufenthalte, Arbeitslosigkeit und vorzeitige Verrentung. Eine Verringerung der Häufigkeit dieser Parameter könnte z.B. zu einer Reduktion der Erstjahres-Behandlungskosten (zurzeit ca. 30% der Gesamtkosten) führen.
Die Kosten-Effektivitäts-Analyse erweist sich als Studienform mit der geringsten Anfälligkeit für Bias und Confounder. Trotz einer vergleichsweise hohen externen Validität ist das Studiensetting nicht uneingeschränkt übertragbar auf die Versorgungsrealität des deutschen Gesundheitssystems. Es existiert aktuell keine generelle Empfehlung für den Einsatz der Gendiagnostik zur Steuerung der Arzneimitteltherapie in Psychiatrie. Ebenso hat die integrierte Versorgung bisher keinen umfassenden Einzug in den psychiatrischen Behandlungsalltag gefunden, so dass die beschriebenen Limitationen einen positiven Nutzennachweis erschweren. Dennoch ist das Konzept als praktisch umsetzbar zu bewerten.
Schlussfolgerung:
Bei dieser Faktenlage ist das Interesse der GKV an der Veranlassung einer gesundheitsökonomischen Evaluation mit dem Ziel einer Erstattungsfähigkeit des a priori durchgeführten pharmakogenetischen Screenings bei Schizophrenie als eher gering einzustufen. Jedoch lassen das Update der S3-Praxisleitlinie mit dem Einbezug der strukturierten u. integrierten Versorgung sowie der Aktionsplan „Individualisierte Medizin“ des Bundesforschungsministeriums auf eine Fokussierung auf diese Fragestellung und veränderte Interessenlage bzgl. der Initiierung der Pilotstudie hoffen.
Weitere Forschungstätigkeit sowie die praktische Erprobung neuer gendiagnostischen Verfahren sind, basierend auf versorgungsbezogenen Pilotstudien wie der hier konzeptionierten, fachübergreifend erforderlich, um die Relevanz der Methodik für den psychiatrischen Versorgungsalltag zu belegen.Purpose: Development of a health-economic investigation method to study whether a cost reduction under concurrent optimisation of the medical use exists by using pharmacogenetic a- priori- screening with first diagnosis of a schizophrenia. Final objective is the reimbursement of pharmacogenetic diagnostics for the indication schizophrenia in the German health statutory insurance (GKV). Methods: A prospective, randomised and controlled, 3-armed, parallel, open, multicentre pilot study with a duration of 3 years was designed based on the actual status of genetic-diagnostic research as well as the evidence-based therapy of schizophrenia. Study population: 300 patients (1:1:1) aged 18 to 65 years with initial F20 diagnosis (ICD-10). Interventions: pharmacogenetic screening and integrated care; integrated care; standard care. For evaluation of the medical benefit the clinical outcome is measured at defined times with regard to the patients' relevant endpoints mortality, morbidity, quality of life and side effects. In perspective relevant costs are determined by "piggy back" procedure. Results: In view of actually existing limitations within the German health system (e.g., insufficient intersectional medication and information management) the integrated care is considered being a suitable setting to demonstrate the advantage of using pharmacogenetic screening. Nevertheless, the integrated care does not show the general standard of the psychiatric patient's care at the moment. From GKV perspective essential cost drivers of schizophrenia therapy are relapses, hospital stays, unemployment and untimely superannuation. Diminishing the rate of these parametres could lead, e.g., to a reduction of the first year medical costs (at the moment approx. 30% of the total expenses). The cost-effectiveness analysis seems to be the study form with the slightest susceptibility to bias and confounding. In spite of a relatively high external validity the study setting is not unconditionally transferable to the German health system. Currently no general recommendation exists for the application of the genetic diagnostics to manage medication therapy in psychiatry. Up to now also the integrated care has not found a comprehensive entry in psychiatric practice, so that the described limitations are complicating a positive use proof. Nevertheless, the investigational concept can be regarded as feasible. Conclusion: Based on the existing situation the GKV's interest in performing a health-economic evaluation, which is focussed on the reimbursement of pharmacogenetic a priori-diagnostics in schizophrenia, is considered to be low. However, the situation may change in view of the expected update of the S3-practise guideline with the focus on structured and integrated care as well as the action plan „individualised medicine“ of the German federal research ministry. Thus, there is hope for changing interests in a pilot study. Based on care-related pilot studies as presented here, further research activities and practical testing of recent gene diagnostic procedures are necessary to demonstrate the relevance of the methodology for psychiatric practice.
Books on the topic "GBV screening"
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Waldek, Stephen. Fabry disease. Edited by Neil Turner. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0338_update_001.
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Fabry disease is a rare X-linked lysosomal storage disorder in which deficiency of alpha-galactosidase A leads to accumulation of substrate, mostly globotriaosylceramide (Gb3), which causes a progressive, multiorgan disease affecting predominantly the kidneys, skin, heart, and nervous system. Painful peripheral (‘acral’) neuropathy is characteristic. Proteinuria and estimated glomerular filtration rate (eGFR) are strongly associated with risk of progression, but this may be reduced by treatment with angiotensin-converting enzyme inhibitors as well as by enzyme replacement therapy (ERT). ERT was approved in 2001; it improves pain and other neuropathic symptoms, and well-being, and has been proven to clear deposits of Gb3 from tissues, at variable speeds. There is limited randomized controlled trial data but protective effects have been proven for renal outcomes, death, and better outcomes in some other organ systems. Renal function may be protected if ERT is commenced before there is heavy proteinuria or substantial loss of GFR. It is recommended to start ERT as soon as the diagnosis is made in those with very low or absent enzyme. For those with intermediate levels it is recommended to commence treatment only when signs or symptoms appear. Proteinuria and eGFR give most information from a renal point of view, but renal biopsy is also useful for confirming the renal diagnosis and staging the disease as well as monitoring progress in selected cases. Management should include regular screening for complications including myocardial and neurological assessments. It is likely that registries will show progressive rises in median survival with this condition.
Book chapters on the topic "GBV screening"
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Olibet, Ylenia, and Alanna Thain. "Vidéo de Femmes Dans le Parc: Feminist Rhythms and Festival Times Under Covid." In Rethinking Film Festivals in the Pandemic Era and After, 155–75. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-14171-3_8.
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AbstractVidéo de Femmes dans le Parc (VFP) (Women’s Videos in the Park) is a summertime open-air screening of independent short videos, held annually since 1991 at Park La Fontaine in Montreal, Canada, by Groupe Intervention Vidéo (GIV), an independent feminist/queer distribution company. In this essay, we explore VFP’s historical use of public space and its reimagination under Covid’s urgent sanitary crisis and chronic social inequities. Within the media ecology of Montreal’s outdoor cinemas, we see GIV’s creative decision to move VFP online during Covid as part of a longer history of alternative media’s unconventional exhibition modes that address social inequalities. As such, we first situate VFP within GIV’s wider mandate of dissemination of video work by women. We then analyze VFP’s “visual architecture” under Covid, stressing the organizers’ original strategies to reproduce a sense of eventness even through online exhibition. We conclude with questions of embodied and affective labor, including audiences’ wellbeing, artist renumeration, and self-care, that the shift online entails for the organizers of VFP.
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Decker, Michele R., Elizabeth Miller, and Nancy Glass. "Gender-based Violence Assessment in the Health Sector and Beyond." In Preventing Intimate Partner Violence. Policy Press, 2017. http://dx.doi.org/10.1332/policypress/9781447333050.003.0005.
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This chapter discusses the rationale and evidence base for routine screening in the health care sector for gender-based violence (GBV) among patients who present for care. The evidence indicates that the impact of screening without subsequent intervention is limited. The chapter also discusses the policy context for GBV screening and makes recommendations for harnessing the potential of the health and other sectors to create safe environments for identifying and assisting GBV victims.
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Baldwin, Andrew, Nina Hjelde, Charlotte Goumalatsou, and Gil Myers. "Obstetrics." In Oxford Handbook of Clinical Specialties, 1–97. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198719021.003.0001.
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This chapter explores obstetrics, including obstetric histories, abdominal examination, physiological changes in pregnancy, pre-pregnancy counselling, the placenta, plasma chemistry in pregnancy, antenatal care, structural abnormalities and ultrasound, screening and diagnosis of aneuploidy, minor symptoms of pregnancy, hyperemesis gravidarum, sickle cell disease in pregnancy, cardiac disease in pregnancy, drugs used in psychiatry and epilepsy, anaemia, HIV in pregnancy and labour, diabetes mellitus in pregnancy, thyroid disease in pregnancy, jaundice in pregnancy, malaria, renal disease in pregnancy, epilepsy, respiratory disease in pregnancy, connective tissue diseases in pregnancy, hypertension in pregnancy, thromboprophylaxis, thrombophilia in pregnancy, venous thromboembolism, infection, group B streptococcus (GBS), abdominal pain in pregnancy, sepsis in pregnancy and the puerperium, fetal monitoring in labour, pre-eclampsia, prematurity, small for gestational age (SGA), postmaturity (prolonged pregnancy), maternal collapse, antepartum haemorrhage, prelabour rupture of membranes at term, normal labour, induction of labour, management of delay in labour, home birth, pain relief in labour, multiple pregnancy, breech presentation and other malpresentations/malpositions, cord prolapse, shoulder dystocia, meconium-stained liquor, operative vaginal delivery, caesarean section (CS), uterine rupture, mendelson’s syndrome, stillbirth (intrauterine fetal death, IUD), postpartum haemorrhage (PPH), retained placenta, uterine inversion, placenta praevia, accreta and increta, DIC and coagulation defects, amniotic fluid embolism, birth injuries, episiotomy and tears, the puerperium, maternal and perinatal mortality.
Conference papers on the topic "GBV screening"
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Ma, Liang, Jeremy Barker, Changchun Zhou, Biaoyang Lin, and Wei Li. "A Perfused Two-Chamber System for Anticancer Drug Screening." In ASME 2010 International Manufacturing Science and Engineering Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/msec2010-34326.
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A cell culture microfluidic device has been developed to test the cytotoxicity of anticancer drugs while reproducing multi-organ interactions in vitro. Cells were cultured in separate chambers representing the liver and tumor. The two chambers were connected through a channel to mimick the blood flow. Glioblastoma (GBM) cancer cells (M059K) and hepatoma cells (HepG2) were cultured in the tumor and the liver chambers, respectively. The cytotoxic effect of cancer treatment drug Temolozomide (TMZ) was tested using this two chamber system. The experimental results showed that with the liver cells, the cancer cells showed much higher viability than those without the liver cells. This indicates that the liver metabolism has strong effect on the toxicity of the anticancer drug. The results demonstrated that the perfused two chamber cell culture system has the potential to be used as a platform for drug screening in a more physiologically realistic environment.
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Ciarrocchi, Alberto, Wei Quan, Markus Blaser, Maria Hämmerli, and Hektor Meier. "Optical Damage Threshold Screening Methodology for 28 GBd, Long Wavelength Avalanche Photodiodes." In Optical Fiber Communication Conference. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/ofc.2022.th2a.39.
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Ciarrocchi, Alberto, Wei Quan, Markus Blaser, Maria Hämmerli, and Hektor Meier. "Optical Damage Threshold Screening Methodology for 28 GBd, Long Wavelength Avalanche Photodiodes." In Optical Fiber Communication Conference. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/ofc.2022.th2a.39.
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Seedat, F., J. Geppert, C. Stinton, J. Patterson, CS Brown, B. Tan, K. Freeman, et al. "OP34 Universal antenatal culture-based screening for maternal group b streptococcus (gbs) carriage to prevent early-onset gbs disease: a systematic review for the uk national screening committee (nsc)." In Society for Social Medicine, 61st Annual Scientific Meeting, University of Manchester, 5–8 September 2017. BMJ Publishing Group Ltd, 2017. http://dx.doi.org/10.1136/jech-2017-ssmabstracts.34.
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Nwosu, Jazzpin-Cross Chiemerie. "Carbon Capture, Utilisation & Storage in Offshore Facilities." In ADIPEC. SPE, 2022. http://dx.doi.org/10.2118/210805-ms.
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Abstract A group of technological procedures known as "carbon capture and storage" involve transferring and injecting carbon dioxide (CO2) that has been captured from industrial waste gases into geological formations. The acronym CCUS, or carbon capture, utilization, and storage, is a key technique for reducing emissions that can be used across the energy system. Meeting the fluctuating need for energy while reducing the harmful effects on the environment are two challenges faced by oil and gas production in floating, production, storage, and offloading (FPSO)units. The most crucial operational parameters to reduce energy demand, boost efficiency, and enhance production are identified in this study through the integration of screening analysis and thermodynamic analysis of oil and gas processing plants. Therefore, the primary objectives of this work are to determine how much the operational parameters of an FPSO with carbon capture, use, and storage (CCUS) contribute to the overall effect. The input parameters for the sensitivity analysis are chosen from some thermodynamic and structural design variables. To accomplish the objectives, four machine learning-based screening analysis algorithms—Linear Regression, Support Vector Machine (SVM), Analysis of Variance (ANOVA) and Gradient Boosting Machine (GBM) are used. The impact of three actual crude oil compositions with different GORs and CO2 contents is evaluated. The optimal operating pressure settings of CCS greatly minimize the energy consumption and exergy destruction of the main and utility plants, according to a combination of thermodynamic and screening evaluations. The findings also showed that while the total oil output is solely affected by the GOR content, the total power consumption, CCS efficiency, and CCS power consumption are all significantly more sensitive to the fluid reservoir's CO2 content than GOR. The impact of design variable interactions is also critical in affecting the separation efficiency and/or compression unit performance for situations with high CO2 or GOR content.
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Ma, Liang, Lei Gao, Yichen Luo, Huayong Yang, Bin Zhang, Changchun Zhou, JinGyu Ock, and Wei Li. "Flow Analysis of a Porous Polymer-Based Three-Dimensional Cell Culture Device for Drug Screening." In ASME 2018 13th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/msec2018-6313.
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A porous polymer-based three-dimensional (3D) cell culture device has been developed as an in vitro tissue model system for the cytotoxicity of anticancer drug test. The device had two chambers connected in tandem, each loaded with a 3D scaffold made of highly biocompatible poly (lactic acid) (PLA). Hepatoma cells (HepG2) and glioblastoma multiforme (GBM) cancer cells were cultured in the two separate porous scaffolds. A peristaltic pump was adopted to realize a perfusion cell culture. In this study, we focus on cell viability inside the 3D porous scaffolds under flow-induced shear stress effects. A flow simulation was conducted to predict the shear stress based on a realistic representation of the porous structure. The simulation results were correlated to the cell variability measurements at different flow rates. It is shown that the modeling approach presented in this paper can be useful for shear stress predication inside porous scaffolds and the computational fluid dynamics model can be an effective way to optimize the operation parameters of perfused 3D cell culture devices.
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Horenkamp-Sonntag, D., EM Bitzer, and S. Geyer. "Gebärmutterhalskrebs-Früherkennung: Veränderung der jährlichen Screening-Inanspruchnahme im (Lang-) Zeitverlauf auf Basis von GKV-Routinedaten." In „Neue Ideen für mehr Gesundheit“. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1694644.
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Horenkamp-Sonntag, D., EM Bitzer, and S. Geyer. "Behandlungsfade in GKV-Routinedaten: Status-Quo der Screening-Inanspruchnahme beim Gebärmutterhalskrebs vor Einführung des HPV-Tests." In Das Soziale in Medizin und Gesellschaft – Aktuelle Megatrends fordern uns heraus 56. Jahrestagung der Deutschen Gesellschaft für Sozialmedizin und Prävention (DGSMP). Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1732721.
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Barreto, Catharina Mello, Amanda Ferraz Arita, Ana Carolina Coutinho Engelhardt Bravin, Julia Surrage da Matta, Maria de Fatima Araujo da Fonseca, and Pietra Sardinha Silvestre Mousinho. "Epidemiological analysis of strokes in Grande Vitória, Espírito Santo." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.207.
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Introduction: Stroke is a neurological syndrome resulting from a vascular injury that represents one of the main causes of morbidity and mortality in the world. Thus, cerebrovascular diseases are increasing in Brazilian statistics, especially the ischemic stroke, responsible for the highest incidence in cases, therefore characterizing a major public health issue. Methods: In this descriptive and ecological study we used data provided by DATASUS concerning hospitalizations and deaths due to stroke, not specified as hemorrhagic or ischemic, occurred between January 2008 and December 2020 in the region of Grande Vitória, Espírito Santo (GV – ES). Results: Overall, there were 10,199 hospitalizations due to stroke in the GV-ES. The prevalence was 57.2% in brown-skinned people, 26.2% between ages from 60 to 69 years old (26.2%) and 52% in Vitória. Among 2008 until 2014 there was an increase of 788.9% in stroke hospitalizations however between 2015 and 2020 there was a 30.5% reduction. In total there were 1,309 deaths, 64% were brown-skinned people, 29.2% above 80 years old and 51.3% in Vitoria. From 2008 to 2019, a 144.5% increase in the mortality rate was observed. In the analyzes there was no difference regarding the gender. Conclusion: Data analysis inferred that old age and brown skin are risk factors for stroke in GV-ES, thereby requiring greater attention for screening and preventing this disease in those groups. Moreover, there was an increase in the mortality rate, even with reduction in the number of cases, reinforcing the need for effective and resolute care in the region.
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Chang, Cindy, Jack Stapleton, Donna Klinzman, Lars Larson, Hormuzd Katki, Mark Purdue, and Eric A. Engels. "Abstract 2538: GB virus C viremia and subsequent risk of non-Hodgkin lymphoma in the PLCO screening trial." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2538.
Full textReports on the topic "GBV screening"
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Haley, Mark V., Roman G. Kuperman, and Ronald T. Checkai. Aquatic Toxicity Screening of an ACWA Secondary Waste, GB-Hydrolysate. Fort Belvoir, VA: Defense Technical Information Center, January 2009. http://dx.doi.org/10.21236/ada494193.
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Fridman, Eyal, Jianming Yu, and Rivka Elbaum. Combining diversity within Sorghum bicolor for genomic and fine mapping of intra-allelic interactions underlying heterosis. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7597925.bard.
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Heterosis, the enigmatic phenomenon in which whole genome heterozygous hybrids demonstrate superior fitness compared to their homozygous parents, is the main cornerstone of modern crop plant breeding. One explanation for this non-additive inheritance of hybrids is interaction of alleles within the same locus. This proposal aims at screening, identifying and investigating heterosis trait loci (HTL) for different yield traits by implementing a novel integrated mapping approach in Sorghum bicolor as a model for other crop plants. Originally, the general goal of this research was to perform a genetic dissection of heterosis in a diallel built from a set of Sorghum bicolor inbred lines. This was conducted by implementing a novel computational algorithm which aims at associating between specific heterozygosity found among hybrids with heterotic variation for different agronomic traits. The initial goals of the research are: (i) Perform genotype by sequencing (GBS) of the founder lines (ii) To evaluate the heterotic variation found in the diallel by performing field trails and measurements in the field (iii) To perform QTL analysis for identifying heterotic trait loci (HTL) (iv) to validate candidate HTL by testing the quantitative mode of inheritance in F2 populations, and (v) To identify candidate HTL in NAM founder lines and fine map these loci by test-cross selected RIL derived from these founders. The genetic mapping was initially achieved with app. 100 SSR markers, and later the founder lines were genotyped by sequencing. In addition to the original proposed research we have added two additional populations that were utilized to further develop the HTL mapping approach; (1) A diallel of budding yeast (Saccharomyces cerevisiae) that was tested for heterosis of doubling time, and (2) a recombinant inbred line population of Sorghum bicolor that allowed testing in the field and in more depth the contribution of heterosis to plant height, as well as to achieve novel simulation for predicting dominant and additive effects in tightly linked loci on pseudooverdominance. There are several conclusions relevant to crop plants in general and to sorghum breeding and biology in particular: (i) heterosis for reproductive (1), vegetative (2) and metabolic phenotypes is predominantly achieved via dominance complementation. (ii) most loci that seems to be inherited as overdominant are in fact achieving superior phenotype of the heterozygous due to linkage in repulsion, namely by pseudooverdominant mechanism. Our computer simulations show that such repulsion linkage could influence QTL detection and estimation of effect in segregating populations. (iii) A new height QTL (qHT7.1) was identified near the genomic region harboring the known auxin transporter Dw3 in sorghum, and its genetic dissection in RIL population demonstrated that it affects both the upper and lower parts of the plant, whereas Dw3 affects only the part below the flag leaf. (iv) HTL mapping for grain nitrogen content in sorghum grains has identified several candidate genes that regulate this trait, including several putative nitrate transporters and a transcription factor belonging to the no-apical meristem (NAC)-like large gene family. This activity was combined with another BARD-funded project in which several de-novo mutants in this gene were identified for functional analysis.