Journal articles: 'Gastroschisi'

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Luton, D., P. de Lagausie, J. Guibourdenche, M. Peuchmaur, O. Sibony, Y. Aigrain, J. F. Oury, and P. Blot. "Influence of Amnioinfusion in aModel of in utero Created Gastroschisi s in the Pregnant Ewe." Fetal Diagnosis and Therapy 15, no. 4 (2000): 224–28. http://dx.doi.org/10.1159/000021011.

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Stoll, C., Y. Alembik, B. Dott, and M. P. Roth. "Risk factors in congenital abdominal wall defects (omphalocele and gastroschisi): a study in a series of 265 858 consecutive births." Annales de Génétique 44, no. 4 (October 2001): 201–8. http://dx.doi.org/10.1016/s0003-3995(01)01094-2.

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Koivusalo, Antti, Mikko Pakarinen, and Annika Mutanen. "Complicated Gastroschisis Is Associated with Greater Intestinal Morbidity than Gastroschisis or Intestinal Atresia Alone." European Journal of Pediatric Surgery 28, no. 06 (October 4, 2017): 495–501. http://dx.doi.org/10.1055/s-0037-1607198.

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Aim The study aimed to compare outcomes and intestinal morbidity among complicated gastroschisis, isolated gastroschisis, and intestinal atresia. Methods In this retrospective observational single institution study, outcomes and intestinal morbidity were compared among gastroschisis complicated by intestinal atresia or perinatal bowel perforation, isolated gastroschisis, and isolated intestinal atresia. We included two cohorts; the first cohort included 68 consecutive patients with complicated gastroschisis (n = 9), isolated gastroschisis (n = 34), and intestinal atresia (n = 25) managed in our center. The second cohort included 20 patients (12 referred) with intestinal failure due to these underlying etiologies managed by our intestinal rehabilitation team. Results Patients with complicated gastroschisis had a significantly longer need for mechanical ventilation, primary hospital stay, and duration of parenteral nutrition (PN) and developed intestinal failure more often compared with other groups (p < 0.05 for all). Reoperations for surgical complications were also more frequent in patients with complicated gastroschisis (p < 0.05). Among those, who developed intestinal failure, autologous intestinal reconstruction (AIR) surgery was performed in 11 patients with comparable frequency in all groups. Repeated AIR surgery for bowel re-dilatation was required in 3/3 patients with complicated gastroschisis and 0/8 with isolated gastroschisis or intestinal atresia (p = 0.004). Conclusion Complicated gastroschisis is associated with markedly increased intestinal morbidity, reflected by prolonged duration of PN, more frequent reoperations for intestinal complications, and bowel re-dilatation after AIR surgery, when compared with patients with isolated gastroschisis or intestinal atresia.

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Salinas-Torres, Víctor M., Hugo L. Gallardo-Blanco, Rafael A. Salinas-Torres, and Laura E. Martínez de Villarreal. "Database for Gene Variants and Metabolic Networks Implicated in Familial Gastroschisis." Data 4, no. 3 (July 11, 2019): 97. http://dx.doi.org/10.3390/data4030097.

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Gastroschisis is one of the most prevalent human birth defects concerning the ventral body wall development. Recent research has given a better understanding of gastroschisis pathogenesis through the identification of multiple novel pathogenetic pathways implicated in ventral body wall closure. Deciphering the underlying genetic factors segregating among familial gastroschisis allows better detection of novel susceptibility variants than the screening of pooled unrelated cases and controls, whereas bioinformatic-aided analysis can help to address new insights into human biology and molecular mechanisms involved in gastroschisis. Technological advances in DNA sequencing (Next Generation Sequencing), computing power, and machine learning techniques provide opportunities to the scientific communities to assess significant gaps in research and clinical practice. Thus, in an effort to study the role of gene variation in gastroschisis, we employed whole exome sequencing in a Mexican family with recurrence for gastroschisis. Stringent bioinformatic analyses were implemented to identify and predict pathogenetic networks comprised of potential gastroschisis predispositions. This is the first database for gene variants and metabolic networks implicated in familial gastroschisis. The dataset provides information on gastroschisis annotated genes, gene variants, and metabolic networks and constitutes a useful source to enhance further investigations in gastroschisis.

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Ashburn, David A., Thomas Pranikoff, and Charles S. Turner. "Unusual Presentations of Gastroschisis." American Surgeon 68, no. 8 (August 2002): 724–27. http://dx.doi.org/10.1177/000313480206800813.

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Gastroschisis is a defect of the ventral abdominal wall nearly always located to the right of the umbilicus. A relatively low incidence of associated anomalies exists with the most common being nonduodenal intestinal atresia occurring in 10 per cent of patients. Although multiple hypotheses have been proposed the pathogenesis of gastroschisis is unproven and controversial. Herein we describe four infants with rare presentations of gastroschisis: one infant with true left-sided gastroschisis and three infants with unusual patterns of intestinal atresia. At present there is a female preponderance of left-sided gastroschisis as reported in the world literature (five female:two male). These cases illustrate the anatomic spectrum of gastroschisis as well as support intrauterine spontaneous closure of the abdominal wall defect as an etiology for midgut atresia.

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Nitzsche, Katharina, Guido Fitze, Mario Rüdiger, and Cahit Birdir. "Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center." Diagnostics 10, no. 8 (July 30, 2020): 540. http://dx.doi.org/10.3390/diagnostics10080540.

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: The aim of this study was to find a prenatal parameter to be able to predict possible prenatal complications or postnatal surgical options, thus allowing the fetal medicine specialist, together with pediatric surgeons and neonatologists, to improve the counseling of the parents and to determine the timing of delivery and therapy. This was a retrospective analysis of prenatal diagnosis and outcome of fetuses with 34 cases of gastroschisis between the years 2007 and 2017. A total of 34 fetuses with gastroschisis were examined and 33 outcomes registered: 22 cases of simple gastroschisis (66.7%) and 11 cases of complex gastroschisis (33.3%). A cut-off value of 18 mm for intraabdominal bowel dilatation (IABD) showed a positive predictive value (PPV) of 100% for predicting simple gastroschisis. IABD gives the best prediction for simple versus complex gastroschisis (cut-off of 18 mm). Extra-abdominal bowel dilatation (EABD) cut-off values of 10 mm and 18 mm showed low sensitivity and specificity to predict complex gastroschisis.

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Georgeades, Christina, Alyssa Mowrer, Gezzer Ortega, Fizan Abdullah, and Jose H. Salazar. "Improved Mortality of Patients with Gastroschisis: A Historical Literature Review of Advances in Surgery and Critical Care from 1960–2020." Children 9, no. 10 (September 30, 2022): 1504. http://dx.doi.org/10.3390/children9101504.

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The improved survival of gastroschisis patients is a notable pediatric success story. Over the past 60 years, gastroschisis evolved from uniformly fatal to a treatable condition with over 95% survival. We explored the historical effect of four specific clinical innovations—mechanical ventilation, preformed silos, parenteral nutrition, and pulmonary surfactant—that contributed to mortality decline among gastroschisis infants. A literature review was performed to extract mortality rates from six decades of contemporary literature from 1960 to 2020. A total of 2417 publications were screened, and 162 published studies (98,090 patients with gastroschisis) were included. Mortality decreased over time and has largely been <10% since 1993. Mechanical ventilation was introduced in 1965, preformed silo implementation in 1967, parenteral nutrition in 1968, and pulmonary surfactant therapy in 1980. Gastroschisis infants now carry a mortality rate of <5% as a result of these interventions. Other factors, such as timing of delivery, complex gastroschisis, and management in low- and middle-income countries were also explored in relation to gastroschisis mortality. Overall, improved gastroschisis outcomes serve as an illustration of the benefits of clinical advances and multidisciplinary care, leading to a drastic decline in infant mortality among these patients.

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Watanabe, Shunusuke, Tatuya Suzuki, Fujio Hara, Toshihiro Yasui, Naoko Uga, and Atuki Naoe. "Omphalocele and Gastroschisis in Newborns: Over 16 Years of Experience from a Single Clinic." Journal of Neonatal Surgery 6, no. 2 (April 15, 2017): 27. http://dx.doi.org/10.21699/jns.v6i2.530.

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Infants born with potentially life-threatening conditions of omphalocele and gastroschisis may require long-term hospitalization. We aimed to compare the outcomes of these two conditions occurring over a 16-year period (2001-16). It is a retrospective study of 19 newborns undergoing surgery for these two abdominal wall defects (8 patients with omphalocele and 11 cases of gastroschisis). The average birth weights for the newborns with omphaloceles and gastroschisis were 2554.5 g and 2248.6 g respectively. Associated anomalies included trisomy 18, Beckwith-Wiedemann syndrome, congenital heart disease, Meckel’s diverticulum, inguinal hernias, renal deformities, limb deformities, cryptorchidism, body stalk anomalies, and closed gastroschisis. The average hospital stay for the newborns with omphaloceles and gastroschisis were 42.6 days 50.2 days respectively. The time to the start of postoperative nutritional supplementation for the newborns with omphaloceles and gastroschisis were 4.3 days for the infants with omphaloceles and 7.3 days for respectively. The survival rates for the newborns with omphaloceles and gastroschisis were similar, 87.5% and 81.8% respectively. Survival rates in omphalocele correlated negatively with associated anomalies. In gastroschisis cases, strict care is necessary when intestinal dilation is observed via fetal sonography.

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Mohamed, Jamal Abade, Richard Migisha, Felix Oyania, Ann Shikanda Wesonga, Ahmed Abade Mohamed, and Martin Situma. "Patterns and Short Term Outcome of Children with Major Congenital Anterior Abdominal Wall Defects Admitted At Mbarara Regional Referral Hospital, South Western Uganda, from September 2019 to June 2020." American Journal of Health, Medicine and Nursing Practice 7, no. 8 (June 19, 2022): 21–27. http://dx.doi.org/10.47672/ajhmn.1074.

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Background: Omphalocele and gastroschisis are the most common major congenital abdominal wall defects (CAWDs) globally. Mortality among neonates major CAWDs is higher in low-income countries than in high-income countries. This study described the patterns and short-term clinical outcomes of infants with gastroschisis and omphalocele at a regional referral hospital in southwestern Uganda. Methods: A case series was conducted at Mbarara Regional Referral Hospital ten months. Children born with CAWD during the study period 54 samples size were consecutively recruited into the study. Data were entered, cleaned, and analyzed using Stata version 15. Descriptive statistics were performed where continuous variables were summarized using median and interquartile ranges, while categorical variables were summarized using frequencies and proportions. Time to mortality was assessed using Kaplan–Meier survival analysis. Results: A total of 54 newborns were recruited into the study, of which 40 (70.04%) had Gastroschisis and 14(25.93%) had omphalocele. The median age of the infants was 9 days with an interquartile range of 4 to 21days. Of the 54 newborns, 30(69.2%) were male within the age group of 1-10 days. Mortality was higher in babies with complex gastroschisis (22) than simple gastroschisis (10). Not administering antibiotics and low birth weight were the factors associated with mortality among infants diagnosed with gastroschisis and omphalocele in the neonatal period. Conclusion: The most common observed defect was gastroschisis, Mortality was generally high among children presenting with gastroschisis. Complex gastroschisis has a poorer prognosis than simple gastroschisis over 30 days follow up period. Non-use of antibiotics before referral to a health facility and low birth weight were the factors associated with mortality among infants diagnosed with gastroschisis and omphalocele in the neonatal period. Recommendation: The most common pattern observed was Gastroschisis. The majority of children presenting with Omphalocele were more likely to survive for 30 days. There is a need for timely referral for babies born with congenital anterior abdominal wall defects.

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Jolley, Alexandra Frances, Elizabeth Jane Beare, Jeremy Granger, Catherine Lucy Cord-Udy, Peter Muller, and Lynette Moore. "Intrauterine Fetal Death With Vanishing Gastroschisis and Post Mortem Examination Findings." Pediatric and Developmental Pathology 20, no. 2 (January 25, 2017): 158–62. http://dx.doi.org/10.1177/1093526616683872.

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We present a severe case of vanishing gastroschisis resulting in intrauterine death with post mortem examination findings. Gastroschisis is defined as a full thickness paraumbilical abdominal wall defect associated with evisceration of fetal intestine. It is almost always right-sided. Vanishing gastroschisis is an extremely rare form of gastroschisis that results in short bowel syndrome due to exteriorized bowel disconnected from the lumen of the rest of the bowel proximally as well as distally in association with partial or complete closure of the abdominal wall. This case is only the second published case of vanishing gastroschisis resulting in intrauterine fetal death including post mortem examination findings. It highlights the importance of being aware of this rare form of gastroschisis and provides insights regarding pathogenesis, ultrasound surveillance, and antenatal counseling.

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Ruschkowski, Brittany, Anthea Lafreniere, Dina El Demellawy, and David Grynspan. "Gastroschisis Is Associated With Placental Delayed Villous Maturation." Pediatric and Developmental Pathology 23, no. 3 (September 22, 2019): 197–203. http://dx.doi.org/10.1177/1093526619875877.

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Gastroschisis is a congenital abnormality characterized by visceral herniation through an abdominal wall defect. While the cause of gastroschisis is unknown, it has been linked to risk factors including young maternal age, smoking, and alcohol use during pregnancy. To date, the only established placental correlate is amniocyte vacuolization. Based on our clinical experience, we hypothesized that delayed villous maturation (DVM) is also associated with gastroschisis. We conducted a retrospective slide review of 23 placentas of neonates with gastroschisis. Additionally, we selected 2 control groups of placentas: 1 with a previous diagnosis of DVM and 1 with normal villous morphology. All placentas were randomized and reviewed by 2 perinatal pathologists, who were blinded to the group; DVM and amniocyte vacuolization were assessed. Gastroschisis was associated with increased placental DVM in 65.2% of cases (vs 13.6% of controls; P = .0007) and increased amniocyte vacuolization in 52.2% of cases (vs 9.1% of controls; P = .003) compared to the control group. Based on the normal and DVM groups, kappa agreement between current slide review and initial pathology diagnosis was 0.419, indicating moderate agreement. Our study shows that gastroschisis is associated with placental DVM. This association may be due to (1) a common upstream factor contributing to both gastroschisis and DVM or (2) DVM may be a consequence of the altered placental and amniotic environment in the context of gastroschisis.

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Ferreira, Rui Gilberto, Carolina Rodrigues Mendonça, Carolina Leão de Moraes, Fernanda Sardinha de Abreu Tacon, Lelia Luanne Gonçalves Ramos, Natalia Cruz e Melo, Lourenço Sbragia, Waldemar Naves do Amaral, and Rodrigo Ruano. "Ultrasound Markers for Complex Gastroschisis: A Systematic Review and Meta-Analysis." Journal of Clinical Medicine 10, no. 22 (November 9, 2021): 5215. http://dx.doi.org/10.3390/jcm10225215.

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Although gastroschisis is often diagnosed by prenatal ultrasound, there is still a gap in the literature about which prenatal ultrasound markers can predict complex gastroschisis. This systematic review and meta-analysis aimed to investigate the ultrasound markers that characterize complex gastroschisis. A systematic review of the literature was conducted according to the guidelines of PRISMA. The protocol was registered (PROSPERO ID CRD42020211685). Meta-analysis was displayed graphically on Forest plots, which estimate prevalence rates and risk ratios, with 95% confidence intervals, using STATA version 15.0. The combined prevalence of intestinal complications in fetuses with complex gastroschisis was 27.0%, with a higher prevalence of atresia (about 48%), followed by necrosis (about 25%). The prevalence of deaths in newborns with complex gastroschisis was 15.0%. The predictive ultrasound markers for complex gastroschisis were intraabdominal bowel dilatation (IABD) (RR 3.01, 95% CI 2.22 to 4.07; I2 = 15.7%), extra-abdominal bowel dilatation (EABD) (RR 1.55, 95% CI 1.01 to 2.39; I2 = 77.1%), and polyhydramnios (RR 3.81, 95% CI 2.09 to 6.95; I2 = 0.0%). This review identified that IABD, EABD, and polyhydramnios were considered predictive ultrasound markers for complex gastroschisis. However, evidence regarding gestational age at the time of diagnosis is needed.

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Puvabanditsin, Surasak, Robin Burger, Vidya Puthenpura, Lauren Walzer, Adaora Madubuko, Christine Minerowicz, and Rajeev Mehta. "A Giant Gastroschisis Associated with Pulmonary Hypoplasia and Spinal Anomaly: A Case Report and a Literature Review." Case Reports in Pathology 2018 (2018): 1–4. http://dx.doi.org/10.1155/2018/8378769.

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Gastroschisis most often occurs as an isolated anomaly and extragastrointestinal associations are rare. Most commonly, the anomalies associated with gastroschisis are cardiac and central nervous system abnormalities. Respiratory insufficiency has sometimes been reported in association with giant abdominal wall defects. Poor outcomes and prolonged ventilator support have been reported in giant gastroschisis and omphalocele, especially if associated with herniation of the majority of the liver. We report a case of a large gastroschisis that was associated with a kyphoscoliosis and pulmonary hypoplasia.

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Pawar, Naresh, Pramila Sharma, Punit Singh Parihar, and Manika Boipai. "Vanishing gastroschisis with jejunal atresia and extreme short bowel syndrome: A case series." Journal of Neonatal Surgery 10 (January 12, 2021): 7. http://dx.doi.org/10.47338/jns.v10.932.

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Background: Vanishing gastroschisis may occur due to spontaneous partial or complete closure of anterior abdominal wall defect around the viscera, leading to small bowel ischemia and resultant entry/exit level atresia and extremely short length of the remaining bowel. The prognosis is very poor, even after aggressive surgery, and requires prolonged total parenteral nutrition. Case Series: We report two female neonates, one with closed and another with closing vanishing gastroschisis, associated with jejunal atresia and extreme short bowel syndrome. In both patients, the antenatal scans showed gastroschisis without the evidence of vanishing gastroschisis. In both neonates, palliative surgeries were done. Both patients died after a few days due to short bowel syndrome and sepsis. Conclusion: When antenatally detected gastroschisis presents with closed or closing anterior abdominal wall defect, (vanishing gastroschisis), the parents/caregivers must be counseled about the poor prognosis of this condition. A tailored approach to either palliation or aggressive therapy is essential in this rare condition.

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Williams, Sadie, Matthew Leonard, Eric Hall, Jose Perez, Jacqueline Wessel, and Paul Kingma. "Evaluation of Early Onset Sepsis, Complete Blood Count, and Antibiotic Use in Gastroschisis." American Journal of Perinatology 35, no. 04 (October 30, 2017): 385–89. http://dx.doi.org/10.1055/s-0037-1607420.

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Objective Gastroschisis is a congenital defect in which the abdominal viscera herniate through the abdominal wall. In this population, antibiotics are often initiated immediately following delivery; however, this may be unnecessary as infections typically develop as a consequence of chronic issues in gastroschisis. The objective of this study was to evaluate the incidence of culture positive early onset sepsis, the reliability of the immature to mature neutrophil count (I:T) ratio as an infectious biomarker, and antibiotic use in infants with gastroschisis. Study Design This retrospective chart review analyzed clinical data from 103 infants with gastroschisis and 103 weight-matched controls that were evaluated for early onset infection. Results Compared with the control group, there was a significantly increased percentage of infants with an I:T ratio > 0.2 in the gastroschisis group (43% vs. 12%, p < 0.001) and an increased percentage of infants exposed to greater than 5 days of antibiotics regardless of their I:T ratio (75% vs. 6%, p < 0.001). There were no episodes of culture positive early onset sepsis in either group. Conclusion Our results indicate that I:T ratio is not a reliable marker of infection in gastroschisis, and suggest that empiric septic evaluation and antibiotic use, immediately following delivery in gastroschisis infants, may be unnecessary.

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Tatic, Milanka, Radoica Jokic, Svetlana Bukarica, and Vladimir Borisev. "Clinical analysis of congenital abdominal wall defects - omphalocele and gastroschisis." Medical review 59, no. 7-8 (2006): 347–55. http://dx.doi.org/10.2298/mpns0608347t.

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Introduction. This is a retrospective analysis of therapeutic approaches and treatment outcomes of congenital abdominal wall defects (omphalocele and gastroschisis) in a five year period. The aim of this study was to identify factors which can affect the prognosis of future therapeutic procedures. Material and methods. We evaluated 13 children, 7 with omphalocele (2 female/5 male; mean birth weight of 2862 g; mean gestational age of 37 weeks), and 6 patients with gastroschisis (2 female/4 male; mean birth weight of 2640 g; mean gestational age of 36/2 weeks). All patients were treated at the Clinic of Pediatric Surgeiyfrom 1999 to 2003. Results. In this study, thirteen cases of congenital abdominal wall defects (omphalocele and gastroschisis) were retrospectively investigated. All patients underwent prenatal ultrasound. Omphalocele was prenatally detected in 42.8% of fetuses, and gastroschisis in 16.7%. Coexisting anomalies were present in 57.1% of patients with omphalocele and in 16.7% of newborns with gastroschisis. Three patients with omphalocele were treated operatively, and four only conservatively. The abdominal wall of patients with gastroschisis was primarily closed in three patients. Two patients required a staged abdominal wall closure. One patient with gastroschisis and intestinal atresia underwent primary closure after partial intestinal resection and enterostomy. Based on these responses, a management protocol (algorithm) was recommended. The most common postoperative complication, in 7 cases of omphalocele, was mechanical ileus (n=l), whereas among patients with gastroschisis the commonest were mechanical ileus (n=l) and intestinal perforation (n=1). The mortality of patients with omphalocele was 52% and with gastroschisis 66.7%. Conclusion. A strategy designed to optimize antenatal and neonatal factors is expected to increase the survival rate of patients with abdominal wall defects. .

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Berdawd, Salar Sabah, and Abdulrahman Omar Taha. "Early Outcome of Patient Born with Gastroschisis and Omphalocele." Journal of the Faculty of Medicine Baghdad 64, no. 3 (October 17, 2022): 117–22. http://dx.doi.org/10.32007/jfacmedbagdad.6431901.

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Background: Gastroschisis and omphalocele are the most common congenital defects of the anterior abdominal wall which need urgent and prompt intervention post-operative time outcomes of gastroschisis and omphalocele differ between different countries, especially between developed and developing countries. Objectives: Is to determine the early outcome of patients born with gastroschisis and omomphalocele Patients and Methods: An analytical study including 30 patients (11 gastroschisis and 19 omphaloceles) were treated in Erbil city during 2015 -2018. Patients with associated bladder and cloacal exstrophies were excluded. Results: Female to male ratio was 1.3:1, and the mean age at presentation was 11.7 hours. The Mean weight was 2.86 kg. the Majority of patients25 (83.3%) were term. In Nineteen cases (63.3%)were delivered vaginally (9 gastroschisis and 10comphalocele), prenatally diagnosis was done in 9(30%). The Mean size of the defect was 3.7cm, and the content was mixed in 7(23.3%). Primary repair has performed in 18(60%), a silo in 8(26.7%), and 4(13.3%) treated none surgically (all were omphalocele). Operations have been done within 24 hours of arrival in 16(61.5%). Associated anomalies have been found in 11(57.9%) patients with omphaloceles and only 2(18.2%) patients with gastroschisis. The mean period of hospital stays was6 days. Mortality among the gastroschisis patients were 8(72%), but only 4(21.1%) for omphalocele patients. Conclusion: Gastrochisis and omphalocele constitute a considerable part of neonatal surgical problems and their management is still challenging. Omphalocele cases were more likely to have associated congenital anomalies and gastroschisis, if the associated anomalies were confined to the gastrointestinal tract. There was a high mortality rate, especially in patients with gastroschisis and ruptured omphalocele due to a lack of intensive care units, facilities, and trained personnel to look after such high-risk patients.

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Guanà, Riccardo, Lucia Marocco, Salvatore Garofalo, Elisa Zambaiti, Alessandro Pane, Federico Scottoni, Fabio Fusaro, Giulia Perucca, and Fabrizio Gennari. "A case of vanishing gastroschisis with short bowel syndrome treated by total parenteral nutrition and intestinal lengthening procedures." SAGE Open Medical Case Reports 11 (January 2023): 2050313X2311574. http://dx.doi.org/10.1177/2050313x231157490.

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The diagnosis of vanishing gastroschisis is made when in the presence of a full-thickness intrauterine abdominal wall defect the eviscerated loops are incarcerated in the fascial interruption. Four types of vanishing gastroschisis are described (A–D). We report on the case of a newborn with a vanishing gastroschisis-D. Gastroschisis was diagnosed at the 19th week of gestation, confirmed at the 30th, when the herniated loops previously visible to the right of the funiculus were no longer visualized. At the 32nd week, delivery was induced. The neonate weighed 1600 g, and the abdomen was distended, free from skin defects. On surgical exploration, the jejunum was 13 cm in length, with a blind ending. The post-atretic intestine measured 22 cm. A jejunostomy and a colostomy were built. The child received total parenteral nutrition for 13 months due to short bowel syndrome and was then subjected to intestinal lengthening procedure when she was 18 months old. Vanishing gastroschisis is a rare entity with a worse prognosis of the “classic” gastroschisis.

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Khalil, BA, JC Gillham, L. Foresythe, R. Harding, T. Johnston, C. Wright, and A. Morabito. "Successful management of short gut due to vanishing gastroschisis – case report and review of the literature." Annals of The Royal College of Surgeons of England 92, no. 5 (July 2010): e10-e13. http://dx.doi.org/10.1308/147870810x12659688852437.

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Vanishing gastroschisis is a rare in utero complication of gastroschisis. It is associated with a high mortality. We present a case report of an infant with vanishing gastroschisis that was managed with a combination of reconstructive bowel surgery and hepatosparing parenteral nutrition. The technique is described and a review of the literature is provided.

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Tauriainen, Asta, Ulla Sankilampi, Arimatias Raitio, Tuomas Tauriainen, Ilkka Helenius, Kari Vanamo, and Anna Hyvärinen. "The association of perinatal and clinical factors with outcomes in infants with gastroschisis—a retrospective multicenter study in Finland." European Journal of Pediatrics 180, no. 6 (February 2, 2021): 1875–83. http://dx.doi.org/10.1007/s00431-021-03964-w.

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AbstractThe aim of the present study was to assess the prognostic factors for the outcome of gastroschisis in Finland. A retrospective multicenter study of gastroschisis patients born between 1993 and 2015 in four Finnish university hospitals was undertaken, collecting perinatal, surgical, and clinical data of neonates for uni- and multifactorial modeling analysis. The aim of the present study was to identify risk factors for mortality and the composite adverse outcome (death and/or short bowel syndrome or hospital stay > 60 days). Of the 154 infants with gastroschisis, the overall survival rate was 90.9%. In Cox regression analysis, independent risk factors for mortality included liver herniation, pulmonary hypoplasia, relaparotomy for perforation or necrosis, abdominal compartment syndrome, and central line sepsis. Furthermore, a logistic regression analysis identified central line sepsis, abdominal compartment syndrome, complex gastroschisis, and a younger gestational age as independent predictors of the composite adverse outcome.Conclusion: The risk of death is increased in newborns with gastroschisis who have liver herniation, pulmonary hypoplasia, abdominal compartment syndrome, relaparotomy for perforation or necrosis, or central line–associated sepsis. Special care should be taken to minimize the risk of central line sepsis in the clinical setting. What is known:• Gastroschisis is a relatively rare congenital anomaly of the abdominal wall and its incidence is increasing.• Complex gastroschisis has been reported to increase risk of mortality and complications.What is new:• Central line sepsis was found to be independently associated with mortality in gastroschisis patients.• Liver herniation was also significantly associated with mortality.

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Hijkoop, Annelieke, Hanneke IJsselstijn, René M. H. Wijnen, Dick Tibboel, Joost van Rosmalen, and Titia E. Cohen-Overbeek. "Prenatal markers and longitudinal follow-up in simple and complex gastroschisis." Archives of Disease in Childhood - Fetal and Neonatal Edition 103, no. 2 (June 14, 2017): F126—F131. http://dx.doi.org/10.1136/archdischild-2016-312417.

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ObjectiveWe aimed to identify gestational-age corrected prenatal ultrasound markers of complex gastroschisis, and to compare physical growth and neurodevelopment between children with simple and complex gastroschisis.DesignWe included prenatally diagnosed gastroschisis patients from 2000 to 2012 who joined our longitudinal follow-up programme. Associations between complex gastroschisis and prenatal ultrasound markers collected at 30 weeks’ gestation and prior to delivery were tested using logistic regression. Physical growth (SD scores (SDS)), mental and psychomotor developmental index (MDI, PDI; Bayley Scales of Infant Development) were recorded at 12 and 24 months. Data were analysed using general linear models and compared with population norms.ResultsData of 61 children were analysed (82% of eligible cases). Extra-abdominal bowel dilatation at 30 weeks’ gestation was significantly associated with complex gastroschisis (OR (95% CI): 5.00 (1.09 to 22.98)), with a high negative (88%) but low positive (40%) predictive value. The mean (95% CI) height SDS at 12 months (−0.46 (–0.82 to –0.11)), and weight SDS at 12 and 24 months (−0.45 (–0.85 to –0.05), and −0.44 (−0.87 to –0.01), respectively) fell significantly below 0 SDS. MDI and PDI were significantly below 100 at 24 months; 93 (88 to 99) and 83 (78 to 87), respectively). Children with complex gastroschisis had a significantly lower PDI (76 (68 to 84)) than those with simple gastroschisis (94 (90 to 97), p<0.001).ConclusionsPrenatal ultrasound markers could not reliably distinguish between simple and complex gastroschisis. Children with complex gastroschisis may be at increased risk for delayed psychomotor development; they should be monitored more closely, and offered timely intervention.

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Raitio, Arimatias, Asta Lahtinen, Johanna Syvänen, Teemu Kemppainen, Eliisa Löyttyniemi, Mika Gissler, Anna Hyvärinen, and Ilkka Helenius. "Gastroschisis in Finland 1993 to 2014—Increasing Prevalence, High Rates of Abortion, and Survival: A Population-Based Study." European Journal of Pediatric Surgery 30, no. 06 (December 31, 2019): 536–40. http://dx.doi.org/10.1055/s-0039-3401797.

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Abstract Introduction The study aims to assess the changes in prevalence and mortality of gastroschisis, and to identify associated anomalies. Materials and Methods It is a population-based nationwide study. All gastroschisis cases were identified in the Finnish Register of Congenital Malformations and the Care Register for Health Care from 1993 to 2014 including live births, stillbirths, and terminations of pregnancy due to fetal anomalies. Associated anomalies were recorded, and analyzed, and prevalence and infant mortality were calculated. Results There were 320 cases of gastroschisis; 235 (73%) live births, 16 (5%) stillbirths, and 69 (22%) terminations of pregnancy. Live birth prevalence of gastroschisis in Finland was lower than generally reported (1.73 in 10,000). However, due to relatively high rates of abortion, our total prevalence of 2.57/10,000 was similar with other reports. The most common risk factor was young maternal age. Babies with gastroschisis were born prematurely, on average on the 36th week and most are delivered by caesarean section. There was a significant increasing trend in live birth prevalence (p = 0.0018). Overall infant mortality was 7.7% (18/235), 7.2% (16/222) in simple gastroschisis and 15% (2/13) in complex gastroschisis. Associated anomalies were rare both in aborted fetuses and neonates, and there was only one case with a chromosomal abnormality. Conclusion Gastroschisis is usually an isolated anomaly with increasing birth prevalence and excellent survival rates. Regardless of the good prognosis, the abortion rates in Finland are higher than previously reported, and we hypothesize this to be due to lack of appropriate antenatal counselling.

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Gandara, Carlos André Tarrio, Eduardo Spadari Araújo, and Ubirajara Índio Carvalho da Motta. "Chicken embryo as an experimental model for the study of gastroschisis." Acta Cirurgica Brasileira 23, no. 3 (June 2008): 247–52. http://dx.doi.org/10.1590/s0102-86502008000300006.

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PURPOSE: To reproduce the experimental model of gastroschisis in chicken embryos and to prove that the histopathological changes that occur in this model can be compared to those in human gastroschisis. METHODS: A total of 278 Leghorn hen (Gallus domesticus) eggs were used. The embryos were divided into three groups: the gastroschisis group, in which the umbilical cord was opened through an orifice made in the eggshell, and the intestinal loops were exposed to a mixture of amniotic liquid and allantoid; the mixture group, in which the amniotic fluid and allantoid were simply mixed without manipulating the umbilical stump and without exposing intestinal loops; and the control group which consisted of normal embryos in which no procedure was performed. The procedures were performed on the 13th day of embryo development and the study ended on the 19th day, when the intestinal loops of the embryos were removed and sent for conventional histological study and digital morphometric analysis. RESULTS: At the end of the experiment, 23 live embryos were obtained in the gastroschisis group (11.1% survival), and 18 of these presented exposed intestinal loops (8.7% success). The embryos of the gastroschisis group weighed less than those of the other two groups. The gastroschisis group also developed intestinal changes consisting of the thickening of the intestinal wall, inflammatory infiltration of the serosa and mucosa, ischemic changes in the intestinal wall and formation of a fibrin layer over the loops. These findings are characteristic of human gastroschisis and were not observed in the two other groups studied. CONCLUSION: The experimental model in chicken embryos proved able to reproduce the intestinal changes of human gastroschisis.

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Marques, Alexandra Tavares, José Estevão-Costa, Henrique Soares, and Ana Catarina Fragoso. "Short and Medium-term Outcomes of Omphalocele and Gastroschisis: A Survey from a Tertiary Center." Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 44, no. 01 (January 2022): 010–18. http://dx.doi.org/10.1055/s-0041-1736299.

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Abstract Objective To characterize and compare the outcomes of omphalocele and gastroschisis from birth to 2 years of follow-up in a recent cohort at a tertiary center. Methods This is a retrospective clinical record review of all patients with gastroschisis and omphalocele admitted to the Neonatal Intensive Care Unit between January 2009 and December 2019. Results There were 38 patients, 13 of whom had omphalocele, and 25 of whom had gastroschisis. Associated anomalies were present in 6 patients (46.2%) with omphalocele and in 10 (41.7%) patients with gastroschisis. Compared with patients with omphalocele, those with gastroschisis had younger mothers (24.7 versus 29.6 years; p = 0.033), were born earlier (36 versus 37 weeks, p = 0.006), had lower birth weight (2365 ± 430.4 versus 2944.2 ± 571.9 g; p = 0.001), and had a longer hospital stay (24 versus 9 days, p = 0.001). The neonatal survival rate was 92.3% for omphalocele and 91.7% for gastroschisis. Thirty-four patients were followed-up over a median of 24 months; 13 patients with gastroschisis (59.1%) and 8 patients with omphalocele (66.7%) had at least one adverse event, mainly umbilical hernia (27.3% vs 41.7%), intestinal obstruction (31.8% vs 8.3%), or additional surgical interventions (27.3% vs 33.3%). Conclusion Despite the high proportion of prematurity, low birth weight, and protracted recovery, gastroschisis and omphalocele (without chromosomal abnormalities) may achieve very high survival rates; on the other hand, complications may develop in the first years of life. Thus, a very positive perspective in terms of survival should be transmitted to future parents, but they should also be informed that substantial morbidity may occur in the medium term.

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Pereyaslov, A. A. "Review of the theories of gastroschisis pathogenesis." Paediatric Surgery. Ukraine, no. 4(69) (December 30, 2020): 86–89. http://dx.doi.org/10.15574/ps.2020.69.86.

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Gastroschisis and omphalocele are the most common congenital malformations of the abdominal wall that required surgical correction. Despite of the long history of the gastroschisis’ study, there is no generally accepted theory of the pathogenesis of this malformation. There are numerous theories of the pathogenesis of gastroschisis discussed in the modern literature: disorders of differentiation of embrionic mesenchyme as the result of teratogenic influence on the early stages of the embryonic development; rupture of amniotic membrane at the base of the umbilical cord; vascular disorders during of the embryonic development; disorders of the yolk-sac escape. Each of existing theories has its supporters and opponents. It is no generally accepted theory of the pathogenesis of gastroschisis. Most likely is the rupture of physiological hernia along the umbilical cord in its pars flaccid, with the subsequent elongation of the midgut out of the abdominal cavity with the vascular compression, especially of venous and lymphatic vessels. Narrow mesenteric root and narrow-sized defect may contribute to various complications that jeopardize the ultimate prognosis. Further studies are needed to finalize the pathogenesis of gastroschisis. No conflict of interest was declared by the author. Key words: gastroschisis, pathogenesis, vascular disorders, embryonic disorders.

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de Souza, Suzana, Oscar Kenji Nihei, and Cezar Rangel Pestana. "High prevalence of gastroschisis in Brazilian triple side border: A socioenvironmental spatial analysis." PLOS ONE 16, no. 2 (February 26, 2021): e0247863. http://dx.doi.org/10.1371/journal.pone.0247863.

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This research investigated the spatial association between socioenvironmental factors and gastroschisis in Brazilian triple side border. A geographic analysis for gastroschisis prevalence was performed considering census sector units using Global Moran Index, Local Indicator of Spatial Association Analysis and Getis Ord statistics. Sociodemographic factors included rate of adolescent and parturients over 35 years; population with no income and above 5 minimum wages; rate of late prenatal; and proximity to power transmission lines. Logistic regression models were applied to verify the association between socio-environmental factors and prevalence of gastroschisis. No global spatial correlation was observed in the distribution of gastroschisis (Moran´s I = 0.006; p = 0.319). However, multiple logistic regression showed census sectors with positive cases had higher probability to power transmission lines proximity (OR 3,47; CI 95% 1,11–10,79; p = 0,031). Yet, spatial scan statistic showed low risk for gastroschisis in southern city region (OR = 0; p = 0.035) in opposite to power transmission lines location. The study design does not allow us to attest the causality between power transmission lines and gastroschisis but these findings support the potential exposure risk of pregnant to electromagnetic fields.

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Razin, Maksim P., and L. M. Zheleznov. "TO THE QUESTION OF THE TERATOGENESIS OF GASTROSCHISIS." Russian Journal of Pediatric Surgery 22, no. 6 (December 21, 2018): 321–22. http://dx.doi.org/10.18821/1560-9510-2018-22-6-321-322.

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Gastroschisis is a severe congenital malformation of the development, characterized by celosoma (defect in the anterior abdominal wall and intrauterine intestinal eventration). The origin of the malformation is currently not fully investigated. Most authors consider the cause of gastroschisis to be a violation of the formation of the anterior abdominal wall, in contrast to omphalocele, which is unanimously considered a malrotation of the first period of rotation of the midgut. The authors compare known facts about gastroschisis and new literary (including experimental) data. The analysis allows us to conclude gastroschisis to be an associated defect of intestinal malrotation and development of the anterior abdominal wall.

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Abuzneid, Yousef S., Sadi A. Abukhalaf, Duha Rabi, Abdelrahman Rabee, Safwan Mashhour, and Radwan Abukarsh. "Sutureless Approach for Gastroschisis Patients in Palestine." Case Reports in Surgery 2020 (August 24, 2020): 1–4. http://dx.doi.org/10.1155/2020/8732781.

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Gastroschisis is a ventral abdominal wall congenital defect with bowel herniation outside the abdominal cavity. Gastroschisis traditional management is the primary operative closure surgery (POCS), but the sutureless silo approach (SSA), a novel alternative, gains wide acceptance in the developed countries and across nations. This study describes the first-ever gastroschisis patient managed with the sutureless silo approach in Palestine. In addition, we shall use this case as the very first nucleus for the upcoming gastroschisis management in our referral hospital because the SSA yields a reduced hospital stay which is fundamental to our institution due to the limited number of beds and lower management costs to the hospital and families.

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Shankar, Kaushaki, Parveen Kumar, Ashish Jain, and Abhishek Chopra. "Fetus with Lateral Gastroschisis Born to a Celiac Mother." Journal of Neonatal Surgery 8, no. 1 (January 22, 2019): 9. http://dx.doi.org/10.47338/jns.v8.343.

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Gastroschisis is a rare anterior abdominal wall defect which develops secondary to an early embryonic vascular defect. We report here a rare site of gastroschisis involving the posterior aspect of lateral abdominal wall on the right side, born to a celiac mother. There is no reported literature on any association between gastroschisis and celiac disease. We propose here possible role of palmitic acid pathway in this index case.

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Durmaz, Lidya-Olgu, Susanne Eva Brunner, Andreas Meinzer, Thomas Franz Krebs, and Robert Bergholz. "Fetal Surgery for Gastroschisis—A Review with Emphasis on Minimally Invasive Procedures." Children 9, no. 3 (March 15, 2022): 416. http://dx.doi.org/10.3390/children9030416.

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(1) Background: The morbidity of gastroschisis is defined by exposure of unprotected intestines to the amniotic fluid leading to inflammatory damage and consecutive intestinal dysmotility, the viscero-abdominal disproportion which results in an abdomen too small to incorporate the herniated and often swollen intestine, and by associated pathologies, such as in complex gastroschisis. To prevent intestinal damage and to provide for growth of the abdominal cavity, fetal interventions such as amnio exchange, gastroschisis repair or covering have been evaluated in several animal models and human trials. This review aims to evaluate the reported techniques for the fetal treatment of gastroschisis by focusing on minimally invasive procedures. (2) Methods: We conducted a systematic database search, quality assessment and analyzed relevant articles which evaluate or describe surgical techniques for the prenatal surgical management of gastroschisis in animal models or human application. (3) Results: Of 96 identified reports, 42 eligible studies were included. Fetal interventions for gastroschisis in humans are only reported for EXIT procedures and amnio exchange. In animal models, particularly in the fetal sheep model, several techniques of open or minimally invasive repair of gastroschisis or covering the intestine have been described, with fetoscopic covering being the most encouraging. (4) Discussion: Although some promising minimally invasive techniques have been demonstrated in human application and animal models, most of them are still associated with relevant fetal morbidity and mortality and barely appear to be currently applicable in humans. Further research on specific procedures, instruments and materials is needed before any human application.

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Spinder, Nynke, Lynn M. Almli, Tania A. Desrosiers, Kathryn E. Arnold, Jorieke E. H. Bergman, Hans Kromhout, H. Marike Boezen, Hermien E. K. de Walle, Carissa Rocheleau, and Jennita Reefhuis. "Maternal occupational exposure to solvents and gastroschisis in offspring - National Birth Defects Prevention Study 1997–2011." Occupational and Environmental Medicine 77, no. 3 (January 16, 2020): 172–78. http://dx.doi.org/10.1136/oemed-2019-106147.

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ObjectivesThe aim of this study was to assess the association between maternal occupational exposure to solvents and gastroschisis in offspring.MethodsWe used data from the National Birth Defects Prevention Study, a large population-based case-control study of major birth defects conducted in 10 US states from 1997 to 2011. Infants with gastroschisis were ascertained by active birth defects surveillance systems. Control infants without major birth defects were selected from vital records or birth hospital records. Self-reported maternal occupational histories were collected by telephone interview. Industrial hygienists reviewed this information to estimate exposure to aromatic, chlorinated and petroleum-based solvents from 1 month before conception through the first trimester of pregnancy. Cumulative exposure to solvents was estimated for the same period accounting for estimated exposure intensity and frequency, job duration and hours worked per week. ORs and 95% CIs were estimated to assess the association between exposure to any solvents or solvent classes, and gastroschisis risk.ResultsAmong 879 cases and 7817 controls, the overall prevalence of periconceptional solvent exposure was 7.3% and 7.4%, respectively. Exposure to any solvent versus no exposure to solvents was not associated with gastroschisis after adjusting for maternal age (OR 1.00, 95% CI 0.75 to 1.32), nor was an association noted for solvent classes. There was no exposure-response relationship between estimated cumulative solvent exposure and gastroschisis after adjusting for maternal age.ConclusionOur study found no association between maternal occupational solvent exposure and gastroschisis in offspring. Further research is needed to understand risk factors for gastroschisis.

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Ibrahim, Tri M., Harsali Lampus, and Jeiny Thomas. "Gastroschisis: Initial Management according to General Practitioner Competence." Medical Scope Journal 3, no. 2 (March 30, 2022): 165. http://dx.doi.org/10.35790/msj.v3i2.39122.

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Abstract: Gastroschisis is the most common congenital defect in the abdominal wall in the last 30 years. This may be related to increased incidence of prematurity and increased survival rate of premature babies. Defects in the abdominal wall usually occur less than 4 cm, located at the junction of umbilicus and normal skin.Relatively young maternal age (<21 years), as well as habits of consuming alcohol and drugs can increase the risk of gastroschisis.Diagnosis can be confirmed at prenatal stage by using USG, and at postnatal stage. Initial treatment consists of fluid resuscitation, oxygenation, decompressed nasograstic tube (NGT), and hypothermia prevention. In conclusion, gastroschisis needs immediate treatment by prevention of hypothermia in infants, administration of fluid and oxygen, and closure of defect. The overall survival rate is quite good and the prognosis depends on the condition of the gut at birth. Keywords: gastroschisis Abstrak: Gastroschisis merupakan defek kongenital pada dinding abdomen yang paling umum ditemukan dalam 30 tahun terakhir. Hal ini mungkin terkait dengan peningkatan kejadian prema-turitas dan peningkatan kelangsungan hidup bayi prematur.Defek pada dinding abdomen terjadi biasanya kurang dari 4 cm dan terletak di antara sambungan umbilikus dan kulit normal. Usia ibu yang relatif muda (<21 tahun), kebiasaan mengonsumsi alkohol serta obat-obatan dapat mening-katkan risiko terjadinya gastroschisis. Diagnosis dapat ditegakkan saat prenatal dengan USG, dan postnatal. Penatalaksanaan awal meliputi resusitasi cairan, pemberian oksigenasi, pemasangan nasogastric tube (NGT) dekompresi, serta mencegah terjadinya hipotemia. Simpulan tulisan ini ialah gastroschisis memerlukan penanganan segera dengan melakukan pencegahan terjadinya hipotermia pada bayi, pemberian cairan, pemberian oksigenasi, dan penutupan defek. Tingkat kelangsungan hidup secara keseluruhan cukup baik dan prognosis tergantung pada kondisi usus saat lahir.Kata kunci: gastroschisis

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Chaganti, PadmavathiDevi, Zahid Akifa, BharatRao Natta, UshaBhargavi Emani, Sravani Ponnada, and Sasank Ramanavarapu. "Gastroschisis." Journal of Dr. NTR University of Health Sciences 1, no. 3 (2012): 177. http://dx.doi.org/10.4103/2277-8632.102447.

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Chabra, Shilpi, and Christine A. Gleason. "Gastroschisis." NeoReviews 6, no. 11 (November 2005): e493-e499. http://dx.doi.org/10.1542/neo.6-11-e493.

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Devi, Rimpi. "Gastroschisis." International Journal of Nursing Education and Research 9, no. 1 (2021): 108–12. http://dx.doi.org/10.5958/2454-2660.2021.00027.2.

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Nunez-Hoyo, Marisol, Graham G. Ashmead, and Jeffrey R. Crass. "Gastroschisis." Journal of Computer Assisted Tomography 16, no. 6 (November 1992): 986–88. http://dx.doi.org/10.1097/00004728-199211000-00031.

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Nichol, P. F. "Gastroschisis." BMJ 343, no. 15 2 (November 15, 2011): d7124. http://dx.doi.org/10.1136/bmj.d7124.

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Lund, Carolyn Houska, Kathryn Bauer, and Margarita Berrios. "Gastroschisis." Journal of Perinatal & Neonatal Nursing 21, no. 1 (January 2007): 63–68. http://dx.doi.org/10.1097/00005237-200701000-00013.

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Mayhew, James F., and George Mychaskiw. "Gastroschisis." Pediatric Anesthesia 19, no. 1 (November 27, 2008): 54. http://dx.doi.org/10.1111/j.1460-9592.2008.02815.x.

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Saada, Julien, Jean-Fran??ois Oury, Edith VUILLARD, Jean Guibourdenche, Pascal De Lagausie, Ghislaine Sterkers, Joseph P. Bruner, and Dominique Luton. "Gastroschisis." Clinical Obstetrics and Gynecology 48, no. 4 (December 2005): 964–72. http://dx.doi.org/10.1097/01.grf.0000184777.87545.a1.

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Torfs, Claudine, Cynthia Curry, and Peter Roeper. "Gastroschisis." Journal of Pediatrics 116, no. 1 (January 1990): 1–6. http://dx.doi.org/10.1016/s0022-3476(05)81637-3.

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Gharpure, Vivek. "Gastroschisis." Journal of Neonatal Surgery 1, no. 4 (October 1, 2012): 60. http://dx.doi.org/10.47338/jns.v1.11.

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O'Connell, Rachel V., Sarah K. Dotters-Katz, Jeffrey A. Kuller, and Robert A. Strauss. "Gastroschisis." Obstetrical & Gynecological Survey 71, no. 9 (September 2016): 537–44. http://dx.doi.org/10.1097/ogx.0000000000000344.

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King, John, and Debbie Fraser Askin. "Gastroschisis: Etiology, Diagnosis, Delivery Options, and Care." Neonatal Network 22, no. 4 (January 2003): 7–12. http://dx.doi.org/10.1891/0730-0832.22.4.7.

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Gastroschisis, one of the more common congenital abdominal wall defects, results in herniation of fetal abdominal viscera into the amniotic cavity. This article discusses theories about gastroschisis etiology, in utero diagnostic tools, delivery options, and postdelivery care. Included are detailed considerations regarding immediate interventions after delivery to support the infant’s thermal and fluid management needs and to protect the exposed bowel. Surgical options and postoperative care issues and complications are reviewed, as are respiratory distress and vena cava compression from increased abdominal pressure, nutritional support, and interventions related to the prevention of infection. Giving birth to an infant with gastroschisis is an upsetting experience for parents. Evidence suggests, however, that with today’s advances in neonatal care and nutrition and with meticulous attention, the survival rate for infants born with gastroschisis can be excellent.

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Abdel-Latif, Mohammed, Mohamed Hisham Soliman, Khaled Mohaned El-Asmar, Mohamed Abdel-Sattar, Ibrahim M. Abdelraheem, and Ehab A. El-shafei. "Closed Gastroschisis." Journal of Neonatal Surgery 6, no. 3 (August 17, 2017): 61. http://dx.doi.org/10.21699/jns.v6i3.599.

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Closed gastroschisis is a rare entity usually associated with intestinal atresia and short bowel syndrome. We report two cases of closed gastroschisis presenting with neonatal intestinal obstruction and para-umbilical evisceration without an abdominal defect.

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Kayastha, P., S. Paudel, RK Ghimire, and MA Ansari. "Gastroschisis and Omphalocele: A Case report." Nepalese Journal of Radiology 2, no. 1 (October 23, 2012): 42–45. http://dx.doi.org/10.3126/njr.v2i1.6980.

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Fetal gastroschisis and omphalocele are congenital defects of abdominal wall that are often diagnosed by prenatal ultrasound done for routine screening or for obstetric indications such as evaluating an elevated maternal serum alpha fetoprotein (AFP). Prenatal ultrasound could potentially identify the overwhelming majority of abdominal wall defects and accurately distinguish omphalocele from gastroschisis. Here we report two cases of gastroschisis and omphalocele diagnosed at routine prenatal ultrasound. NJR I VOL 2 I ISSUE 1 42-45 Jan-June, 2012 DOI: http://dx.doi.org/10.3126/njr.v2i1.6980

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Shamima, Mosammat Nargis, Mohd Alamgir Hossain, Shahela Jesmin, Nargis Jahan, and Noshin Tasnim. "Gastroschisis and Omphalocele: A Case report." TAJ: Journal of Teachers Association 27, no. 2 (November 28, 2018): 63–64. http://dx.doi.org/10.3329/taj.v27i2.38993.

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Fetal gastroschisis and omphalocele are congenital defects of abdominal wall that are often diagnosed by prenatal ultrasound done for routine screening or for obstetric indications such as evaluating an elevated maternal serum alpha fetoprotein (AFP).Regular antenatal checkup and Prenatal ultrasound could potentially identify the overwhelming majority of abdominal wall defects and accurately distinguish omphalocele from gastroschisis. But in a developing country like Bangladesh neglected patients fail to seek antenatal visit and prenatal diagnosis. Here we report a case of gastroschisis and omphalocele diagnosed incidentally during last trimester.TAJ 2014; 27(2): 58-62

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Shamima, Mosammat Nargis, Mohd Alamgir Hossain, Shahela Jesmin, Nargis Jahan, and Noshin Tasnim. "Gastroschisis and Omphalocele: A Case report." TAJ: Journal of Teachers Association 28, no. 2 (December 2, 2018): 64–65. http://dx.doi.org/10.3329/taj.v28i2.39082.

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Fetal gastroschisis and omphalocele are congenital defects of abdominal wall that are often diagnosed by prenatal ultrasound done for routine screening or for obstetric indications such as evaluating an elevated maternal serum alpha fetoprotein (AFP).Regular antenatal checkup and Prenatal ultrasound could potentially identify the overwhelming majority of abdominal wall defects and accurately distinguish omphalocele from gastroschisis. But in a developing country like Bangladesh neglected patients fail to seek antenatal visit and prenatal diagnosis. Here we report a case of gastroschisis and omphalocele diagnosed incidentally during last trimester.TAJ 2015; 28(2): 64-65

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Malinowski, W., and I. Biskup. "The Sonographic Prenatal Diagnosis of Congenital Defects of the Anterior Abdominal Wall Based on our Own Study of Twin Pregnancies – Gastroschisis." Acta geneticae medicae et gemellologiae: twin research 46, no. 02 (April 1997): 101–4. http://dx.doi.org/10.1017/s0001566000000659.

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AbstractThe authors present gastroschisis which occurred in a surviving fetus after the co-twin demise in a monochorionic pregnancy. They analyze the problems of prenatal ultrasound diagnosis of gastroschisis stressing the adequate planning of delivery with necessary additional diagnostic and therapeutic efforts.

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Raitio, Arimatias, Johanna Syvänen, Asta Tauriainen, Anna Hyvärinen, Ulla Sankilampi, Mika Gissler, and Ilkka Helenius. "Congenital abdominal wall defects and cryptorchidism: a population-based study." Pediatric Surgery International 37, no. 7 (January 31, 2021): 837–41. http://dx.doi.org/10.1007/s00383-021-04863-9.

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Abstract Purpose Several studies have reported high prevalence of undescended testis (UDT) among boys with congenital abdominal wall defects (AWD). Due to rarity of AWDs, however, true prevalence of testicular maldescent among these boys is not known. We conducted a national register study to determine the prevalence of UDT among Finnish males with an AWD. Methods All male infants with either gastroschisis or omphalocele born between Jan 1, 1998 and Dec 31, 2015 were identified in the Register of Congenital Malformations. The data on all performed operations were acquired from the Care Register for Health Care. The register data were examined for relevant UDT diagnosis and operation codes. Results We identified 99 males with gastroschisis and 89 with omphalocele. UDT was diagnosed in 10 (10.1%) infants with gastroschisis and 22 (24.7%) with omphalocele. Majority of these required an operation; 8/99 (8.1%) gastroschisis and 19/89 (21.3%) omphalocele patients. UDT is more common among AWD patients than general population with the highest prevalence in omphalocele. Conclusions Cryptorchidism is more common among boys with an AWD than general population. Furthermore, omphalocele carries significantly higher risk of UDT and need for orchidopexy than gastroschisis. Due to high prevalence testicular maldescent, careful follow-up for UDT is recommended.

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Journal articles on the topic 'Gastroschisi'

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