Relevant bibliographies by topics / Ganoderma

Academic literature on the topic 'Ganoderma'

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Published: 4 June 2021
Last updated: 19 February 2022

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Journal articles on the topic "Ganoderma"

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Hajjaj, Hassan, Catherine Macé, Matthew Roberts, Peter Niederberger, and Laurent B. Fay. "Effect of 26-Oxygenosterols from Ganoderma lucidum and Their Activity as Cholesterol Synthesis Inhibitors." Applied and Environmental Microbiology 71, no. 7 (July 2005): 3653–58. http://dx.doi.org/10.1128/aem.71.7.3653-3658.2005.

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ABSTRACT Ganoderma lucidum is a medicinal fungus belonging to the Polyporaceae family which has long been known in Japan as Reishi and has been used extensively in traditional Chinese medicine. We report the isolation and identification of the 26-oxygenosterols ganoderol A, ganoderol B, ganoderal A, and ganoderic acid Y and their biological effects on cholesterol synthesis in a human hepatic cell line in vitro. We also investigated the site of inhibition in the cholesterol synthesis pathway. We found that these oxygenated sterols from G. lucidum inhibited cholesterol biosynthesis via conversion of acetate or mevalonate as a precursor of cholesterol. By incorporation of 24,25-dihydro-[24,25-3H2]lanosterol and [3-3H]lathosterol in the presence of ganoderol A, we determined that the point of inhibition of cholesterol synthesis is between lanosterol and lathosterol. These results demonstrate that the lanosterol 14α-demethylase, which converts 24,25-dihydrolanosterol to cholesterol, can be inhibited by the 26-oxygenosterols from G. lucidum. These 26-oxygenosterols could lead to novel therapeutic agents that lower blood cholesterol.
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Boromenskyi, D., N. Bisko, G. Al-Maali, and O. Polishchuk. "The contents of ganoderic acids in mycellium of different Ganoderma species (Ganodermataceae) obtained by different methods of cultivation." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 84, no. 1 (2021): 14–18. http://dx.doi.org/10.17721/1728_2748.2021.84.14-18.

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The effect of different cultivation methods on the content of ganoderic acids of 7 species, 10 strains of the Ganoderma genus (Ganoderma applanatum 1899; Ganoderma сarnosum 2502; Ganoderma lucidum 1904; Ganoderma resinaceum 2477, 2503; Ganoderma sinense 2516; Ganoderma tsugae 1848, 2024, 2566, Ganoderma oregonense 2560) genus fungi from the IBK Mushroom Culture Collection M.G. Kholodny Institute of Botany of National Academy of Sciences of Ukraine was investigated. It has been shown that the submerged cultivation method is more efficient for the accumulation of ganoderic acids for five strains. In the mycelium of the strain G. sinense 2516 was the highest content of ganoderic acids – 25.2 ± 1.5 mg / g. The productivity (yeld) of ganoderic acids synthesis is much higher with using the submerged culture cultivation method for mycelium of all used species and strains since the use of this method provides the accumulation of much more biomass in comparison with the static liquid cultivation method. The highest yield amount of ganoderic acids was in the mycelium of the G. tsugae 2024 and G. tsugae 2566 species, namely: 0.35 ± 0.019 and 0.36 ± 0.028 g / l. It was proved that the modified extraction method significantly reduces the extraction time of ganoderic acids. Extraction time is reduced from 14 to 2 days. For the G. sinense 2516 and G. tsugae 2024 strains was determined content of the ganoderic acids and their yield in dynamics of grows in the submerged culture on 6, 8, 10, 12, 14, 16, 18 and 20 day of cultivation. The highest amount of the ganoderic acids content was accumulated by the mycelium of the strain G. sinense 2516 – it was 26.4 ± 1.5 mg / g on the 14th day of cultivation. The highest yield of the ganoderic acids was in G. sinense 2516 on 14th day, and G. tsugae 2024 mycelium on the 16th day of cultivation with the next numbers 0.6 ± 0.031, 0.62 ± 0.033 and 0.62 ± 0.027 g/l.
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Yeung, Steven, Quanlan Chen, Yongbang Yu, Bingsen Zhou, Wei Wu, Xia Li, Ying Huang, and Zhijun Wang. "Quality evaluation of commercial products of Ganoderma lucidum made from its fruiting body and spore." Acta Chromatographica 34, no. 1 (September 1, 2021): 100–113. http://dx.doi.org/10.1556/1326.2020.00825.

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Abstract Ganoderma lucidum (GL), also known as Reishi or Lingzhi, is a medicinal mushroom widely used in traditional and folk medicines. The extracts made from the fruiting body and spore of naturally grown GL are the most frequently used in commercial products. More than 400 compounds have been identified in GL with the triterpenoids considered to be the major active components. Large variations in the chemical components were reported in previous studies and there is no comprehensive study of the content of multiple major triterpenoids in the GL product. In addition, there is no report in the comparison of chemical profiles in different parts of GL (i.e., fruiting body and spore). Determining the chemical composition and comparing the differences between fruiting body and spore are essential for the identity, efficacy and safety of various GL products. In this study, 13 compounds (ganoderenic Acid C, ganoderic Acid C2, ganoderic Acid G, ganoderic Acid B, ganoderenic Acid B, ganoderic Acid A, ganoderic Acid H, ganoderenic Acid D, ganoderic Acid D, ganoderic Acid F, ganoderic Acid DM, ganoderol A, and ergosterol) were selected as the chemical markers. The purpose of this study is to develop an HPLC-DAD fingerprint method for quantification of these active components in GL (spore and fruiting body) and test the feasibility of using the HPLC-DAD fingerprint for quality control or identity determination of GL products. The results showed that this method could determine the levels of the major components accurately and precisely. Among the 13 components, 11 ganoderma acids were identified to be proper chemical markers for quality control of GL products, while ganoderal A was in a very low amount and ergosterol was not a specific marker in GL. The extracts of fruiting body contained more chemical compounds than those of spore, indicating that these 11 compounds could be a better chemical marker for the fruiting body than the spore. The HPLC chemical fingerprint analysis showed higher variability in the quality of GL harvest in different years, while lesser variation in batches harvested in the same year. In conclusion, an HPLC assay detecting 11 major active components and a fingerprinting method was successfully established and validated to be feasible for quality control of most commercial GL products.
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., Surahmaida. "Review: Potensi Berbagai Spesies Ganoderma Sebagai Tanaman Obat." Journal of Pharmacy and Science 2, no. 1 (May 7, 2018): 17–21. http://dx.doi.org/10.53342/pharmasci.v2i1.61.

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ABSTRAKDi dunia, jamur Ganodermatelah dikenal sebagai jamur obat. Ganoderma lebih dikenal dengan sebutan jamur Lingzhi atau Reishi. Dari 2000 spesies Ganoderma, hanya 6 spesies yang telah diteliti memiliki efek potensial dalam bidang kesehatan, yaitu G. lucidum, G. applanatum, G. tsugae, G. oregonense, G. boninense, dan G. neojapanicum. Kandungan senyawa bioaktif yang terkandung di dalam Ganoderma terus dikembangkan dalam pemanfaatannya sebagai obat alternatif. Hal inilah yang menyebabkan jamur Ganoderma bebas dari efek samping.Enam spesies Ganoderma ini memiliki karakteristik dengan berbagai potensi kesehatan yang berbedabeda dan berkhasiat sebagai bahan obat. Dari keenam Ganoderma, hanya G. boninense yang memiliki toksisitas terhadap larva udang Artemia salina.Kata Kunci: Tipe-tipe Ganoderma sp, karakteristik fisik, senyawa bioaktif, manfaat Ganoderma sp. bagi kesehatanABSTRACTIn the world, the fungus Ganoderma has been known as a medicinal mushroom. Ganoderma is known as Lingzhi or Reishi mushroom. From 2000 Ganoderma species, only six species that have been studied have a potential effect on health, namely G. lucidum, G. applanatum, G. tsugae, G. oregonense, G. boninense, and G. neojapanicum. The content of bioactive compounds contained in Ganoderma continue to be developed in their usage as an alternative medicine. This is what causes the fungus Ganoderma is free from side effects. Six speciesof Ganoderma has characteristics with various health potentials that vary and efficacious as a drug ingredient. Of the six Ganoderma, only G. boninense has toxicity to the shrimp larvae of Artemia salina.Keywords: Types of Ganodermasp., physical characteristics, bioactive components, health benefits of Ganoderma sp.
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Wu, Jiumn-Yih, Hsiou-Yu Ding, Tzi-Yuan Wang, Yun-Rong Zhang, and Te-Sheng Chang. "Glycosylation of Ganoderic Acid G by Bacillus Glycosyltransferases." International Journal of Molecular Sciences 22, no. 18 (September 9, 2021): 9744. http://dx.doi.org/10.3390/ijms22189744.

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Ganoderma lucidum is a medicinal fungus abundant in triterpenoids, its primary bioactive components. Although numerous Ganoderma triterpenoids have already been identified, rare Ganoderma triterpenoid saponins were recently discovered. To create novel Ganoderma saponins, ganoderic acid G (GAG) was selected for biotransformation using four Bacillus glycosyltransferases (GTs) including BtGT_16345 from the Bacillus thuringiensis GA A07 strain and three GTs (BsGT110, BsUGT398, and BsUGT489) from the Bacillus subtilis ATCC 6633 strain. The results showed that BsUGT489 catalyzed the glycosylation of GAG to GAG-3-o-β-glucoside, while BsGT110 catalyzed the glycosylation of GAG to GAG-26-o-β-glucoside, which showed 54-fold and 97-fold greater aqueous solubility than that of GAG, respectively. To our knowledge, these two GAG saponins are new compounds. The glycosylation specificity of the four Bacillus GTs highlights the possibility of novel Ganoderma triterpenoid saponin production in the future.
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Chang, Te-Sheng, Chien-Min Chiang, Tzi-Yuan Wang, Yu-Li Tsai, Yu-Wei Wu, Huei-Ju Ting, and Jiumn-Yih Wu. "One-Pot Bi-Enzymatic Cascade Synthesis of Novel Ganoderma Triterpenoid Saponins." Catalysts 11, no. 5 (April 30, 2021): 580. http://dx.doi.org/10.3390/catal11050580.

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Ganoderma lucidum is a medicinal fungus whose numerous triterpenoids are its main bioactive constituents. Although hundreds of Ganoderma triterpenoids have been identified, Ganoderma triterpenoid glycosides, also named triterpenoid saponins, have been rarely found. Ganoderic acid A (GAA), a major Ganoderma triterpenoid, was synthetically cascaded to form GAA-15-O-β-glucopyranoside (GAA-15-G) by glycosyltransferase (BtGT_16345) from Bacillus thuringiensis GA A07 and subsequently biotransformed into a series of GAA glucosides by cyclodextrin glucanotransferase (Toruzyme® 3.0 L) from Thermoanaerobacter sp. The optimal reaction conditions for the second-step biotransformation of GAA-15-G were found to be 20% of maltose; pH 5; 60 °C. A series of GAA glucosides (GAA-G2, GAA-G3, and GAA-G4) could be purified with preparative high-performance liquid chromatography (HPLC) and identified by mass and nucleic magnetic resonance (NMR) spectral analysis. The major product, GAA-15-O-[α-glucopyranosyl-(1→4)-β-glucopyranoside] (GAA-G2), showed over 4554-fold higher aqueous solubility than GAA. The present study demonstrated that multiple Ganoderma triterpenoid saponins could be produced by sequential actions of BtGT_16345 and Toruzyme®, and the synthetic strategy that we proposed might be applied to many other Ganoderma triterpenoids to produce numerous novel Ganoderma triterpenoid saponins in the future.
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Kao, Chi, Amalini C. Jesuthasan, Karen S. Bishop, Marcus P. Glucina, and Lynnette R. Ferguson. "Anti-cancer activities of Ganoderma lucidum: active ingredients and pathways." Functional Foods in Health and Disease 3, no. 2 (February 9, 2013): 48. http://dx.doi.org/10.31989/ffhd.v3i2.65.

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Ganoderma lucidum, commonly referred to as Lingzhi, has been used in Asia for health promotion for centuries. The anti-cancer effects of G. lucidum have been demonstrated in both in vitro and in vivo studies. In addition, the observed anti-cancer activities of Ganoderma have prompted its usage by cancer patients alongside chemotherapy. The main two bioactive components of G. lucidum can be broadly grouped into triterpenes and polysaccharides. Despite triterpenes and polysaccharides being widely known as the major active ingredients, the different biological pathways by which they exert their anti-cancer effect remain poorly defined. Therefore, understanding the mechanisms of action may lead to more widespread use of Ganoderma as an anti-cancer agent. The aim of this paper is to summarise the various bioactive mechanisms that have been proposed for the anti-cancer properties of triterpenes and polysaccharides extracted from G. lucidum. A literature search of published papers on NCBI with keywords “Ganoderma” and “cancer” was performed. Among those, studies which specifically examined the anti-cancer activities of Ganoderma triterpenes and polysaccharides were selected to be included in this paper. We have found five potential mechanisms which are associated with the anti-cancer activities of Ganoderma triterpenes and three potential mechanisms for Ganoderma polysaccharides. In addition, G. lucidum has been used in combination with known anti-cancer agents to improve the anti-cancer efficacies. This suggests Ganoderma’s bioactive pathways may compliment that of anti-cancer agents. In this paper we present several potential anti-cancer mechanisms of Ganoderma triterpenes and polysaccharides which can be used for the development of Ganoderma as an anti-cancer agent.Keywords: Ganoderma lucidum, cancer, bioactive pathways, triterpene, polysaccharide
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Guo, Wei-Ling, Jian-Bin Guo, Bin-Yu Liu, Jin-Qiang Lu, Min Chen, Bin Liu, Wei-Dong Bai, Ping-Fan Rao, Li Ni, and Xu-Cong Lv. "Ganoderic acid A from Ganoderma lucidum ameliorates lipid metabolism and alters gut microbiota composition in hyperlipidemic mice fed a high-fat diet." Food & Function 11, no. 8 (2020): 6818–33. http://dx.doi.org/10.1039/d0fo00436g.

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Ganoderic acid A from Ganoderma lucidum has the potential to prevent hyperlipidemia, modulates the composition of gut microbiota in hyperlipidemic mice, and significantly attenuates the liver metabolite profile in hyperlipidemic mice.
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ACHMAD, ACHMAD, and DEKA YULISMAN. "POTENSI DUA ISOLAT LOKAL Pleurotus sp. SEBAGAI ANTAGONIS TERHADAP Ganoderma sp." Jurnal Penelitian Tanaman Industri 17, no. 4 (June 19, 2020): 174. http://dx.doi.org/10.21082/jlittri.v17n4.2011.174-178.

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<p>ABSTRAK</p><p>Pleurotus sp. merupakan salah satu jamur yang lebih dikenalsebagai jamur pangan. Selain sebagai jamur pangan, jamur tersebut jugadilaporkan memiliki kemampuan antimikrobial. Dalam penelitian inidipelajari potensi isolat lokal Pleurotus sp. sebagai antagonis terhadapfungi patogen Ganoderma sp. yang merupakan penyebab penyakit pentingpada tanaman perkebunan terutama kelapa sawit. Penelitian dilakukan diLaboratorium Penyakit Hutan Fakultas Kehutanan IPB dari bulan Julisampai dengan Oktober 2004. Penelitian menggunakan dua isolat lokalPleurotus sp.1 dan Pleurotus sp.4 yang merupakan koleksi LaboratoriumPenyakit Hutan Fakultas Kehutanan IPB. Inokulum Ganoderma sp.diperoleh dengan mengisolasi langsung tubuh buah dari tegakan mahoniyang tumbuh di samping Laboratorium Penyakit Hutan. Uji antagonismein vitro dilakukan dengan metode oposisi langsung dalam cawan petriberdiameter 9 cm. Peubah yang diamati adalah jari-jari koloni patogenyang tumbuh ke arah antagonis dan terdapat atau tidaknya zonapenghambatan pada batas kedua koloni jamur. Analisis data dilakukandengan uji-t berpasangan untuk perlakuan yang relevan. Hasil penelitianmenunjukkan bahwa keberadaan kedua isolat antagonis mampu memper-lambat pertumbuhan menjari Ganoderma sp. Zona penghambatanterbentuk hanya pada antagonisme Ganoderma sp. dengan Pleurotus sp.4tetapi tidak pada antagonisme dengan Pleurotus sp.1. Hal tersebutmenunjukkan perbedaan mekanisme antagonisme pada kedua isolat.</p><p>Kata kunci: Pleurotus ostreatus, Ganoderma sp., antagonisme, antibiosis</p><p>ABSTRACT</p><p>The Antagonistic Potentid of Two Local Isolates ofPleurotus sp. against Ganoderma sp.</p><p>Pleurotus sp. is mushrooms which is more famous as a foodfungus. Aside from being a food, this fungus is also reported to haveantimicrobial capabilities. This research studied the potential of localisolates Pleurotus sp. as antagonists to pathogenic fungi Ganodermasp. Research conducted at the Laboratory of Forest Disease, Faculty ofForestry IPB, from July to October 2004. The study used two local isolatesPleurotus sp.1 and Pleurotus sp.4 which were collectioned from ForestDisease Laboratory of the Faculty of Forestry, IPB. Ganodermasp. inoculum was obtained directly by isolating the fruit body on themahogany stands growing beside the Forest Disease Laboratory.Antagonism in vitro test was conducted using direct opposition in the petridish, 9 cm in diameter. Variables measured were the radius of pathogencolonies which grew in the direction to antagonist colony, and the presenceor absence of inhibition zone at the border of both fungal colonies. Thedata were analyzed with paired t-test for the relevant treatment. The resultsshowed that the existence of two antagonistic isolates were able to inhibitthe growth of Ganoderma sp. Inhibition zone was formed only on theantagonism of Ganoderma sp. with Pleurotus sp.4 but not in antagonismwith Pleurotus sp.1. This shows the mechanism difference of antagonismon both isolates.</p><p>Key words: Pleurotus ostreatus, Ganoderma sp., antagonism, antibiosis</p>
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Sakamoto, Seiichi, Nao Kikkawa, Toshitaka Kohno, Kuniyoshi Shimizu, Hiroyuki Tanaka, and Satoshi Morimoto. "Immunochromatographic strip assay for detection of bioactive Ganoderma triterpenoid, ganoderic acid A in Ganoderma lingzhi." Fitoterapia 114 (October 2016): 51–55. http://dx.doi.org/10.1016/j.fitote.2016.08.016.

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Dissertations / Theses on the topic "Ganoderma"

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Roberts, Lyndal, and lyndalroberts@gmail com. "Australian Ganoderma : identification, growth & antibacterial properties." Swinburne University of Technology. Environment and Biotechnology Centre, 2004. http://adt.lib.swin.edu.au./public/adt-VSWT20060109.114954.

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Ganoderma species are one of the most widely researched fungi because of their reported potent bioactive properties. Although there is much information related to American, European and Asian isolates, little research has been conducted on Australian Ganoderma isolates. Ganoderma may only be imported into Australia under strict quarantine conditions, therefore, the isolation of a native strain that possesses bioactivity may be industrially and commercially significant. Three Australian species of this wood-decomposing fungus were isolated in northern Queensland. In this study, they have been identified as three separate species. Further, they have been studied to determine their optimal growth conditions in liquid culture and assessed for their antibacterial properties. Phylogeny inferred from the Internal Transcribed Spacer Regions (ITS) from the DNA sequences resolved the three Australian Ganoderma species into separate clades. Two isolates were identified to be isolates of Ganoderma cupreum (H1) and Ganoderma weberianum (H2). The third isolate could only be identified to the genus level, Ganoderma species, due to the lack of informative data that could be used for comparison. The effects of short term and long term storage on the viability of the fungi were investigated on agar plates, agar slants and balsa wood at varying temperatures ranging from 10 to 45�C. The most appropriate storage conditions were determined to be �80�C on balsa wood chips for periods of up to 2 years without subculture, and on agar slants at 4�C for up to a maximum of eight weeks. Light was observed to be detrimental to the survival of Ganoderma H1 and Ganoderma H2 during storage. Growth trials using potato dextrose agar plates determined the optimal temperature and pH for mycelial growth to be 30�C and a pH of 6, for all isolates. Subsequent growth trials in liquid media found that glucose, as the carbohydrate source, supported the greatest mycelial growth of Ganoderma H1 and Ganoderma H2 and that galactose and fructose supported the greatest growth of Ganoderma H3. Abstract ii Aqueous (hot water) and organic (hexane (HEX), dichloromethane (DCM), ethyl acetate (EtOAc), methanol (MeOH)) extracts from the liquid cultivated mycelium were assessed for their antibacterial activity using disc diffusion assays. Extracts from the mycelium of Ganoderma H1 exhibited activity against a greater number of Gram positive bacteria than those from Ganoderma H2 and H3. Subsequent studies on the DCM and EtOAc extracts from Ganoderma H1 determined the MIC and MBC against a number of Gram positive bacteria, including Bacillus cereus, B. subtilis, Enterococcus faecalis, Streptococcus pyogenes, Staphylococcus aureus, S. epidermidis and Listeria monocytogenes, as well as Clostridium species, including Clostridium perfringens, C. sporogenes and C. difficile, and some methicillin resistant Staphylococcus aureus (MRSA) strains. Time course growth assays confirmed that the DCM and EtOAc extracts predominantly exhibited bactericidal activity. Finally, the active compounds were determined to be terpenoid in structure with some phenolic groups attached.
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ADASKAVEG, JAMES ELLIOTT. "STUDIES OF GANODERMA LUCIDUM AND GANODERMA TSUGAE (DELIGNIFICATION, MATING SYSTEMS, ROOT ROT, CULTURAL MORPHOLOGY, TAXONOMY)." Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/188172.

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Ganoderma lucidum and G. tsugae are two members of the G. lucidum complex. The authenticity of the two wood-rotting species was demonstrated by comparative studies. Ganoderma lucidum is restricted to hardwoods. Its "smooth" walled basidiospores were characterized by narrow, numerous inter-wall pillars. Isolates of G. lucidum produced chlamydospores in culture and had an average growth of 7.8 mm/da at their optimum temperature range of 30-34 C. Ganoderma tsugae is restricted to conifers. Its basidiospores were "rough" walled and had broad inter-wall pillars. Isolates of G. tsugae did not produce chlamydospores in culture and had an average growth of 2.1 mm/da at the optimum temperature range of 20-25 C. Mating systems were determined for both species as heterothallic and tetrapolar. Interspecific matings of homokaryons were incompatible. Homokaryons of a European G. resinaceum isolate were interfertile with homokaryons from North American collections of G. lucidum. The ability of G. lucidum and G. tsugae to decay wood in vitro was studied using the following woods in agar block decay chambers: grape, oak, mesquite, white fir, and Douglas-fir. Grape wood lost the most weight while mesquite the least. G. lucidum isolates generally caused greater weight loss of all woods than did G. tsugae isolates. Both Ganoderma species caused simultaneous decay in all woods. However, chemical analyses of the decayed blocks indicated that selective delignification by both species also occurred in grape and white fir blocks but not in oak or Douglas-fir blocks. Scanning electron microscopy demonstrated various stages of selective delignification and simultaneous decay of all woods tested. Isolates of Ganoderma lucidum infected Dog Ridge variety grape plants, grown in the greenhouse, from below-ground wood block inoculations. Twenty-four plants were inoculated: one plant died and 4 other plants declined. After 24 months reisolations yielded only G. lucidum from the five declining plants, demonstrating pathogenicity. The fungus developed in the heartwood and, in later stages, invaded the sapwood. Infected plants developed water stress symptoms with leaves wilting, yellowing, and dying. Field grape plants inoculated with the fungus developed decay columns as large as 42 cm in 17 mons. Decay was limited to the heartwood; no foliar symptoms occurred.
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Chan, Sze-yin. "The effects of ganoderma extracts on immune cell subsets." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43781494.

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Welti, Stéphane. "Recherches de substances antitumorales à partir de ganodermes et autres polypores récoltés dans les îles françaises des petites Antilles et contribution à l'inventaire des Ganodermataceae de Martinique, Guadeloupe et dépendances." Lille 2, 2009. http://www.theses.fr/2009LIL2S034.

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En premier lieu, notre travail résume l’état des connaissances sur les Ganodermataceae des Antilles françaises, en se basant sur l’analyse exhaustive de la littérature et sur les récoltes personnelles que nous avons effectuées au cours de 7 missions sur le terrain, en Guadeloupe et en Martinique (2003- 2008). Soixante quatre collections ont été examinées, ainsi que plusieurs types d’espèces décrites des Néotropiques (Ganoderma dussii Pat. , G. Pulverulentum Murrill, G. Subfornicatum Murrill, G. Tuberculosum Murrill). Au total, quinze taxons ont été identifiés dans les Antilles françaises. Les caractères morphologiques de chaque espèce ont fait l’objet d’une description méticuleuse, d’une illustration sur planche ainsi que d’une discussion. De plus, chacune de nos hypothèses portées sur l’identité des espèces s’appuie sur des résultats phylogénétiques. Les espèces suivantes sont citées pour la première fois aux Antilles : anoderma amazonense Weir, Ganoderma flaviporum (Murill) Sacc. & Trotter, Ganoderma subamboinense (P. Hennings) Bazzalo & Wright, Ganoderma tuberculosum Murril. En second lieu, nos recherches ont porté sur la comparaison des activités antiprolifératives de différents extraits méthanoliques de Ganodermataceae Donk récoltés aux Antilles et Guyane françaises et de deux espèces de référence : Ganoderma lucidum européen et ‘Ganoderma lucidum’ asiatique, sur cellules cancéreuses humaines de type prostatique (PC-3), mammaires (MCF- 7) et colorectal (HT-29). Nous avons démontré que certains ganodermes néotropicaux tel le Ganoderma tuberculosum pouvaient aussi inhiber la croissance des cellules cancéreuses de la même façon, sinon plus, que le Ganoderma lucidum utilisé en médecine traditionnelle asiatique et le Ganoderma lucidum européen. Les acides ganodériques A, DM et F, pour lesquels une activité anticancéreuse a été démontrée, n’ont pas été retrouvés dans l’extrait méthanolique de Ganoderma tuberculosum. D’un autre côté, l’extrait de cette espèce contient un composé majoritaire correspondant 256 à un acide ganodérique jusqu’ici jamais décrit : GA FWI. Celui-ci n’a pas montré d’activité antiproliférative significative sur cellules cancéreuses de type PC-3, MCF-7 et HT29. De plus, ce travail a montré que l’activité antiproliférative du G. Lucidum européen est similaire à celle du G. Lucidum traditionnellement utilisé en médecine asiatique excepté pour HT29 pour lesquels aucune activité n’a été démontrée pour l’espèce asiatique. Enfin, notre étude illustre l'importance des investigations taxinomiques fiables, avec des méthodes traditionnelles et moléculaires, afin d'identifier clairement les espèces contenant les molécules spécifiques bioactives.
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Ho, Yee-wa Eva, and 何綺華. "Effects of Ganoderma lucidum on rheumatoid synovial fibroblasts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29489933.

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Chen, Chun, Peng Li, Ye Li, Guan Yao, and Jian-Hua Xu. "Antitumor effects and mechanisms of Ganoderma extracts and spores oil." SPANDIDOS PUBL LTD, 2016. http://hdl.handle.net/10150/622362.

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Ganoderma lucidum is a popular herbal medicine used in China to promote health. Modern studies have disclosed that the active ingredients of Ganoderma can exhibit several effects, including antitumor effects and immunomodulation. The present study evaluated the antitumor effects of self-prepared Ganoderma extracts and spores oil, and investigated the possible underlying mechanisms by observing the effects of the extracts and oil on topoisomerases and the cell cycle. The results showed that Ganoderma extracts and spores oil presented dose-dependent inhibitory effects on tumor cells. The half maximal inhibitory concentration (IC50) values of Ganoderma extracts on HL60, K562 and SGC-7901 cells for 24 h were 0.44, 0.39 and 0.90 mg/ml, respectively; for Ganoderma spores oil, the IC50 values were 1.13, 2.27 and 6.29 mg/ml, respectively. In the in vivo study, the inhibitory rates of Ganoderma extracts (4 g/kg/d, intragastrically) on S180 and H22 cells were 39.1 and 44.6%, respectively, and for Ganoderma spores oil (1.2 g/kg/d, intragastrically) the inhibitory rates were 30.9 and 44.9%, respectively. Ganoderma extracts and spores oil inhibited the activities of topoisomerase I and II. Ganoderma spores oil was shown block the cell cycle at the transition between the G1 and S phases and induce a marked decrease in cyclin D1 levels in K562 cells, with no significant change in cyclin E level. These results suggest that the Ganoderma extracts and spores oil possessed antitumor effects in the in vitro and in vivo studies. The antitumor mechanisms of the extracts and spores oil were associated with inhibitory effects on topoisomerase I and II activities, and for Ganoderma spores oil, the antitumor effects may also be associated with decreased cyclin D1 levels, thus inducing G1 arrest in the cell cycle.
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Mercière, Maxime. "Diversité et bases moléculaires de l’agressivité de Ganoderma Boninense, agent causal de la pourriture basale du stipe chez le palmier à huile (Elaeis guineensis)." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS263/document.

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La compréhension de la structure génétique et de la dynamique des populations, ainsi que les mécanismes moléculaires régissant les interactions entre l’hôte et le pathogène sont des éléments clefs pour la gestion des maladies. Au cours de cette étude nous avons cherché à développer dans un premier temps des marqueurs microsatellites à partir de données issues du séquençage d’un isolat de Ganoderma boninense. Ces marqueurs microsatellites nous ont permis d’étudier la structuration génétique et l’histoire démographique de G. boninense. Le génotypage d’un sous-échantillonnage issus de missions de récolte en Malaisie et à Sumatra nous a permis de mettre en évidence deux groupes principaux au sein de l’Asie du Sud-Est. Nous avons ensuite concentré notre attention sur la région regroupant la Malaisie péninsulaire et l’île de Sumatra, zone historique de développement de la culture industrielle du palmier à huile et d’apparition de la pourriture basale du stipe due à G. boninense, qui semble former une seule population. Nous avons examiné à une échelle géographique plus restreinte cette zone géographique afin de mettre en évidence une potentielle sous structure au sein de cette population. En testant l’effet du fond génétique du palmier d’origine de chaque individu, du nombre de génération de palmier précédent le moment de la récolte de l’individu, ou de la distance géographique sur une possible sous-structure des individus au sein de la zone historique, nous avons mis en évidence qu’aucune sous-structure génétique n’émergeait. En revanche, La comparaison de plusieurs scénarios d’évolution démographique a permis de mettre en évidence un phénomène d’expansion très ancien bien antérieur au début du développement de la culture industrielle du palmier à huile. Pour finir, la comparaison des données transcriptomiques entre des isolats agressifs et non agressifs a permis de souligner la présence d’une centaine de gènes différentiellement exprimés possédant une annotation fonctionnelle. Les résultats de ces deux approches pourront permettre une meilleure gestion de la maladie ainsi que l’amélioration des programmes développement et de gestion des résistances
The understanding of genetic structuration and population dynamic, as well as the molecular mechanisms ruling host/pathogen interaction, are key elements for disease management. During this study, as first step, we were looking to develop microsatellites markers from genomic data obtained from sequencing of a Ganoderma boninense pure strain. Those markers allowed studying genetic structuration and demographic history of G. boninense. Genotyping of a subset of samples from sampling mission in Malaysia and Sumatra have highlighted two main groups in South-East Asia. Then, we focused on a region gathering peninsular Malaysia and Sumatra together, as it is both historical region of industrial oil palm culture development and the first region of basal stem rot observation caused by G. boninense, and to appear as a single population. We examine this region at a lower scale in order to highlight a potential genetic substructure in this population. We tested for effect of genetic tree background of each sample, number of planting generation before sampling and geographical distance between sample in order to observe a potential correlation between genetic substructure and one of those factors. As no correlation appeared, we concluded that this population does not have a genetic substructure. On the other hand, the comparison between several demographic evolution scenarios have shown a strong support for a past expansion event further back in time from the beginning of industrial oil palm culture development. To conclude, the exploration of transcriptomic data between strains owning aggressive or non-aggressive profile showed the differential expression of a hundred genes owning a functional annotation. Results from both approaches will allow the development of better disease management and a better resistance selection and management program
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Chan, Sze-yin, and 陳詩妍. "The effects of ganoderma extracts on immune cell subsets." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43781494.

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Supramaniam, Christina V. "Molecular interaction between Ganoderma boninense and young oil palm." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33689/.

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Oil palm is an important crop to the economy of Malaysia and Indonesia. There have been considerable efforts to improve crop quality of crop to meet the growing demands for edible oil in the world. However, the threat of pests and diseases in Malaysian oil palm has increasingly challenged the production of crude palm oil, sometimes to the point of driving plantations to closure and conversion of estate land for commercial development. The most devastating disease in oil palm is basal stem rot (BSR), caused by the root-rot pathogen Ganoderma boninense. The disease has been observed in both young and mature oil palm and in both inland and coastal plantations. Epidemiology of BSR was explained through infection by spores and by mycelium from previously infected oil palm and coconut stands, and the presence of G. boninense in the basal stem and soil surrounding infected palms. The life cycle of G. boninense could extend to years as the fungus can remain as resting structures in palm tissues and as recalcitrant spores spread by wind and rain splash in estates. Shade house trials have been successful in producing artificially infected Ganoderma-oil palm BSR symptoms. However, the current method uses oil palm seedlings of three to 12 months and involves inoculation with G. boninense that has pre-colonised a rubber wood block for one month. This method requires a minimum of six months to observe BSR-like symptoms, a time consuming effort. The aim of this work was to develop an efficient artificial infection assay that uses clonal oil palm plantlets as hosts for BSR disease through the inoculation of G. boninense isolate GBLS. The experiment was set up with treatments of T1: non-treatment control, T2: wounded plant control and T3: wounded and GBLS-infected plants. During the incubation period of 42 days, T3 plants consistently showed significant stunting (5.18% and 13.41% shorter than T1 and T2, respectively) and loss of weight (57.58% and 61.00% lighter than T1 and T2, respectively). The T3 plants also had significantly thinner leaves (38.70% and 37.71% narrower than T1 and T2, respectively) and lower chlorophyll contents (42.95% and 64.88% lower SPAD readings than T1 and T2, respectively). Disease severity on the T3 plants was 100% by 6 weeks, indicating death of oil palms. The quantity of GBLS DNA present in T3 samples was highest at Day 14, corresponding to the active growth phase of the pathogen, while on Day 42, the quantity of DNA increased to 13.58% of Day 14 readings, indicating continuous growth in vivo. The method developed was time-sensitive and reliable for screening oil palm for response during the plant-pathogen interaction. The work examined the hypothesis that G. boninense utilizes lignin degrading enzymes (LDEs) such as laccase, lignin peroxidase (LiP) and manganese-dependent peroxidase (MnP) to breakdown oil palm lignin, causing primary cell, tissue and stem rot. Therefore, the role of laccase was investigated during the interaction in otherwise symptomless oil palm tissues. A small gene fragment (208 bp) of laccase was isolated from total DNA of G. boninense GBLS and sequencing showed it to contain 89% homology to basidiomycete laccase. GBLS reduced the total lignin content of oil palm in T3 plants (48.86% and 53.18% lower than T1 and T2, respectively). However, neither laccase nor MnP enzymes were produced in significantly higher amounts in T3 as compared to T1 and T2, indicating the need to differentiate the presence of plant and fungal laccases. Transcript abundance for GBLS laccase gene using qPCR indicated that laccase was induced during the interaction, with maximum laccase detected on Day 28. However, this did not place laccase as a virulence factor although the presence of higher amounts of laccase towards the end of the experiment corresponds to loss of lignin and plant death. Therefore, laccase and other LDEs need further investigations to be confirmed as virulence factors. This work reports a novel infection assay for G. boninense interaction with oil palm and was the first study to have investigated the role of G. boninense laccases in the devastating BSR disease.
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PEREIRA, JUNIOR José Antonio de Sousa. "Estudos Farmacognósticos e Atividade Biológica de Ganoderma Parvulum Murrill (basidiomycota, Polyporales, Ganodermataceae)." Universidade Federal de Pernambuco, 2013. https://repositorio.ufpe.br/handle/123456789/10404.

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O uso de cogumelos para fins medicinais é muito antigo, onde o basidiomiceto Ganoderma lucidum tem posição de destaque no Japão e na tradicional medicina chinesa, sendo relatadas atividades antitumorais, antivirais, antibacteriana, dentre outras. Várias espécies com superfície lacada são confundidas com G. lucidum, entre elas Ganoderma parvulum Murrill, uma espécie tropical que pode representar potencial econômico, respeitando-se a biodiversidade local. O presente trabalho objetivou avaliar a atividade antibacteriana, concentração inibitória mínima (CIM) e a atividade citotóxica dos extratos metanólico e em acetato de etila de G. parvulum, a atividade antibacteriana e a CIM do óleo essencial, bem como fornecer dados para caracterização da droga fúngica. Para os extratos estudados, tanto a atividade antibacteriana como citotóxica foram observadas apenas para o extrato em acetato de etila. A atividade antibacteriana foi considerada moderada frente a Staphylococcus aureus, Bacillus subtilis e Micrococcus luteus. A atividade citotóxica em dose única de 50 μg/ml de extrato foi de 71,94 ± 2,04% contra a linhagem de células HT-29 e 90,02 ± 2,17% contra a linhagem de células HEp-2. O óleo essencial teve atividade antimicrobiana contra as bactérias gram-positivas (Staphylococcus aureus, Bacillus subtilis e Micrococcus luteus) e gram-negativas (Escherichia coli, Klebsiella pneumoniae e Pseudomonas aeruginosa), contudo bactérias gram-positivas foram mais susceptíveis ao óleo essencial. Quanto à prospecção micoquímica, os compostos majoritários foram representados pelos esteróides e terpenóides, apresentando também flavonóides, derivados cinâmicos e fenilpropanoglicosídeos. A composição do óleo essencial foi analisada por cromatografia gasosa acoplada a espectroscopia de massas (CG-MS), onde os principais compostos foram o ácido benzóico, o sesquiterpeno aristolona mono-oxigenado, o 2,6-bis (1,1-dimetiletil)-4-metilfenol e o N-(2-hidroxi-4-oxo-4H-quinazolina-3-il)-benzamida. A morfoanatomia foi considerada fundamental para a identificação de G. parvulum, onde características como o tamanho do basidioma, tamanho do basidiósporo, o sistema hifálico, a coloração do contexto e linhas de deposição de material resinoso, foram características essenciais para distinção de G. parvulum. O tamanho das partículas do pó indicou se tratar de um pó moderadamente espesso por simples agregação das partículas, o teor de cinzas totais foi de 1,67 ± 0,14% e a perda por dessecação foi de 13% ± 0,07, dentro dos níveis encontrados para o gênero. Na análise microscópica do pó, a observação de hifas esqueléticas e de esporos de parede dupla e truncados, característicos do gênero, foram importantes para a identificação da droga. Os dados sobre teor de cinzas, perda por dessecação, análise granulométrica e microscópica do pó são inéditos para G. parvulum, bem como as atividades biológicas dos extratos estudados e do óleo essencial.
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Books on the topic "Ganoderma"

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Lin, Zhibin, and Baoxue Yang, eds. Ganoderma and Health. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-32-9421-9.

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Lin, Zhibin, and Baoxue Yang, eds. Ganoderma and Health. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9867-4.

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Flood, J., P. D. Bridge, and M. Holderness, eds. Ganoderma diseases of perennial crops. Wallingford: CABI, 2000. http://dx.doi.org/10.1079/9780851993881.0000.

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Shunü, Liao, ed. Ling zhi zhi yong fa yu xiao guo. Taizhong Shi: Zan yun chu ban she, 1986.

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Shunü, Liao, ed. Ling zhi zhi cai ji, zai pei yu li yong. 3rd ed. Taizhong Shi: Zan yun chu ban she, 1988.

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Ling zhi di ao mi. Taibei Shi: Zheng yi chu ban she, 1988.

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Pagunsan, Levi H. Ganoderma for optimum health and longevity. [United States: s.n.], 2004.

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Yucheng, Dai, ed. Zhongguo ling zhi tu jian. Beijing Shi: Ke xue chu ban she, 2005.

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Murmanis, L. Electron-dense particles in wood decayed by Ganoderma applanatum. [Madison, Wis.?: U.S. Dept. of Agriculture, Forest Products Laboratory], 1986.

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Murmanis, L. Electron-dense particles in wood decayed by Ganoderma applanatum. [Madison, Wis.?: U.S. Dept. of Agriculture, Forest Products Laboratory], 1986.

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Book chapters on the topic "Ganoderma"

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Dong, Caixia, and Quanbin Han. "Ganoderma lucidum 灵芝 (Lingzhi, Ganoderma)." In Dietary Chinese Herbs, 759–66. Vienna: Springer Vienna, 2015. http://dx.doi.org/10.1007/978-3-211-99448-1_85.

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Wagner, Hildebert, Rudolf Bauer, Dieter Melchart, Pei-Gen Xiao, and Anton Staudinger. "Ganoderma — Lingzhi." In Chromatographic Fingerprint Analysis of Herbal Medicines, 633–45. Vienna: Springer Vienna, 2011. http://dx.doi.org/10.1007/978-3-7091-0763-8_54.

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Bährle-Rapp, Marina. "Ganoderma Lucidum Extract." In Springer Lexikon Kosmetik und Körperpflege, 217. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_4164.

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Gong, Ting, Renyi Yan, Jie Kang, and Ruoyun Chen. "Chemical Components of Ganoderma." In Advances in Experimental Medicine and Biology, 59–106. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9867-4_3.

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Su, Zheng-Yuan, and Lee-Yan Sheen. "An Evidence-based Perspective of Ganoderma Lucidum (Lucid Ganoderma) for Cancer Patients." In Evidence-based Anticancer Materia Medica, 245–63. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-0526-5_12.

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Owaid, Mustafa Nadhim. "Ganoderma lucidum: King of Mushroom." In Non-Timber Forest Products, 325–37. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73077-2_14.

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Zhang, Jingsong, Yanfang Liu, Qingjiu Tang, Shuai Zhou, Jie Feng, and Hongyu Chen. "Polysaccharide of Ganoderma and Its Bioactivities." In Advances in Experimental Medicine and Biology, 107–34. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9867-4_4.

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Chen, Ruoyun, and Jie Kang. "Quantitative Analysis of Components in Ganoderma." In Advances in Experimental Medicine and Biology, 135–55. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9867-4_5.

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Wei, Zhen-Hua, and Jian-Jiang Zhong. "Production of Ganoderma lucidum Polysaccharides by Fermentation." In Functional Carbohydrates, 219–56. Boca Raton : CRC Press, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371061-7.

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Govender, Nisha, Wong Mui-Yun, and Robert Russell Monteith Paterson. "Opportunities for New-Generation Ganoderma boninense Biotechnology." In Grand Challenges in Fungal Biotechnology, 477–500. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-29541-7_17.

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Conference papers on the topic "Ganoderma"

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Feng, Zhao-Rui, Huan-Jun Li, and Jun-Wei Xu. "Ganoderic Acid Accumulation and Biosynthetic Gene Expression during Fruiting Body Development in Ganoderma lucidum." In 2015 Asia-Pacific Energy Equipment Engineering Research Conference. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/ap3er-15.2015.83.

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Kien, Pham Van, Doan Thanh Son, and Nguyen Quang Sang. "Study of thermophysical properties of Ganoderma lucidum." In 1ST VAN LANG INTERNATIONAL CONFERENCE ON HERITAGE AND TECHNOLOGY CONFERENCE PROCEEDING, 2021: VanLang-HeriTech, 2021. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0066892.

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Shu Ming Huang, Xin Lin Yang, and He Sun Zhu. "Antitumor effects of triterpene acids extracted from Ganoderma lucidum." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5966079.

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Yanhar, Muhammad Rafiq. "Study Of Composite Hardness With Ganoderma Boninense Mushroom As Filler." In 8th International Conference on Multidisciplinary Research 2019. European Publisher, 2020. http://dx.doi.org/10.15405/epsbs.2020.03.03.84.

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Irene, Liza Isaac, Farah Diba Abu Bakar, Abu Seman Idris, and Abdul Munir Abdul Murad. "Isolation and regeneration protoplast of an oil palm pathogen, Ganoderma boninense." In THE 2015 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4931224.

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Shuming Huang, Jie Zhang, Min Zhang, Shouguo Shen, Xiaoyan Yin, Xiaoyan Shui, and Dayan Wang. "Study on biotransformation of inorganic selenium from Ganoderma lucidum and yeasts." In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering (RSETE). IEEE, 2011. http://dx.doi.org/10.1109/rsete.2011.5966007.

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"In vitro Effects of Ganoderma lucidum Extract on Breast Cancer Cells." In International Conference on Chemical, Environment & Biological Sciences. International Institute of Chemical, Biological & Environmental Engineering, 2014. http://dx.doi.org/10.15242/iicbe.c914126.

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Kien, Pham Van, Doan Thanh Son, and Nguyen Quang Sang. "The optimization of radiofrequency assisted heat pump drying of Ganoderma lucidum." In 1ST VAN LANG INTERNATIONAL CONFERENCE ON HERITAGE AND TECHNOLOGY CONFERENCE PROCEEDING, 2021: VanLang-HeriTech, 2021. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0066669.

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Assis, K., K. P. Chong, A. S. Idris, H. W. Hoong, and C. M. Ho. "Regression analysis for yield loss of oil palm due to Ganoderma disease." In 2015 International Conference on Research and Education in Mathematics (ICREM7). IEEE, 2015. http://dx.doi.org/10.1109/icrem.2015.7357066.

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Alexander, Arnnyitte, Jedol Dayou, and Khim-Phin Chong. "Morphological changes of Ganoderma boninense mycelia after challenged by Trichoderma and Bacillus." In PROCEEDINGS OF THE 23RD SCIENTIFIC CONFERENCE OF MICROSCOPY SOCIETY MALAYSIA (SCMSM 2014). AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4919213.

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Reports on the topic "Ganoderma"

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C.A.Reddy, PI. Structure and Biochemestry of Laccases from the Lignin-Degrading Basidiomycete, Ganoderma lucidum. Office of Scientific and Technical Information (OSTI), June 2005. http://dx.doi.org/10.2172/883001.

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Qin, Li-hong, Chen Wang, Xiao-xue Jiang, You Song, Yao Feng, Li-wei Qin, and Shu-ping Zhang. Effects of Spore Powder of Ganoderma Lucidum on CaSR and apoptosis-related proteins in hippocampus tissue of epilepsy following dementia: a protocol of systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0041.

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