Academic literature on the topic 'Gallic acid'

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Journal articles on the topic "Gallic acid"

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Zhao, Jianping, Ikhlas A. Khan, and Frank R. Fronczek. "Gallic acid." Acta Crystallographica Section E Structure Reports Online 67, no. 2 (January 12, 2011): o316—o317. http://dx.doi.org/10.1107/s1600536811000262.

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Wu, Yundong, Kanggen Zhou, Shuyu Dong, Wei Yu, and Huiqing Zhang. "Recovery of gallic acid from gallic acid processing wastewater." Environmental Technology 36, no. 5 (October 3, 2014): 661–66. http://dx.doi.org/10.1080/09593330.2014.957246.

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Jo, Seongin, Young-Sung Jung, Ye-Ryeong Cho, Ji-Won Seo, Won-Chul Lim, Tae-Gyu Nam, Tae-Gyu Lim, and Sanguine Byun. "Oral Administration of Rosa gallica Prevents UVB−Induced Skin Aging through Targeting the c−Raf Signaling Axis." Antioxidants 10, no. 11 (October 22, 2021): 1663. http://dx.doi.org/10.3390/antiox10111663.

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Rosa gallica is a widely used Rosa species for medicinal and culinary purposes. Rosa gallica has been reported to display antioxidant, anti−inflammatory, and antibacterial activities. However, the effect of Rosa gallica against skin aging in vivo is unknown and its active components have not been fully understood. Oral administration of Rosa gallica prevented UVB−mediated skin wrinkle formation and loss of collagen/keratin fibers in the dorsal skin of mice. Examination of biomarkers at the molecular level showed that Rosa gallica downregulates UVB−induced COX−2 and MMP−1 expression in the skin. Through a direct comparison of major compounds identified using the UHPLC−MS/MS system, we discovered gallic acid as the primary component contributing to the anti-skin aging effect exhibited by Rosa gallica. Examination of the molecular mechanism revealed that gallic acid can potently and selectively target the c−Raf/MEK/ERK/c−Fos signaling axis. In addition, both gallic acid and MEK inhibitor blocked UVB−induced MMP−1 expression and restored collagen levels in a reconstructed 3D human skin model. Collectively, Rosa gallica could be used as a functional ingredient in the development of nutraceuticals against skin aging.
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Okabe, Nobuo, Hasuyo Kyoyama, and Misato Suzuki. "Gallic acid monohydrate." Acta Crystallographica Section E Structure Reports Online 57, no. 8 (July 27, 2001): o764—o766. http://dx.doi.org/10.1107/s1600536801012041.

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Jiang, Ren-Wang, Dong-Sheng Ming, Paul P. H. But, and Thomas C. W. Mak. "Gallic acid monohydrate." Acta Crystallographica Section C Crystal Structure Communications 56, no. 5 (May 15, 2000): 594–95. http://dx.doi.org/10.1107/s0108270100001827.

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Ow, Yin-Yin, and Ieva Stupans. "Gallic Acid and Gallic Acid Derivatives: Effects on Drug Metabolizing Enzymes." Current Drug Metabolism 4, no. 3 (June 1, 2003): 241–48. http://dx.doi.org/10.2174/1389200033489479.

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Singh, U. P., B. K. Sarma, D. P. Singh, and Amar Bahadur. "Studies on exudate-depleted sclerotial development in Sclerotium rolfsii and the effect of oxalic acid, sclerotial exudate, and culture filtrate on phenolic acid induction in chickpea (Cicer arietinum)." Canadian Journal of Microbiology 48, no. 5 (May 1, 2002): 443–48. http://dx.doi.org/10.1139/w02-040.

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Exudate depletion from developing sclerotia of Sclerotium rolfsii Sacc. in culture caused reduced size and weight of sclerotia. Germination of exudate-depleted sclerotia was delayed on Cyperus rotundus rhizome meal agar medium when compared with that of control sclerotia. The exudate-depleted sclerotia caused infection in chickpea (Cicer arietinum) plants in a glasshouse. Different temperatures and incubation periods had no effect on the germination ability of the exudate-depleted sclerotia. Oxalic acid, sclerotial exudate, and culture filtrate of S. rolfsii induced the synthesis of phenolic acids, including gallic, ferulic, chlorogenic, and cinnamic acids, as well as salicylic acid, in treated chickpea leaves. Gallic acid content was increased in treated leaves compared with the untreated controls. Maximum induction of gallic acid was seen in both leaves treated with oxalic acid followed by exudate and leaves treated with culture filtrate. Cinnamic and salicylic acids were not induced in exudate-treated leaves. Ethyl acetate fractionation indicated that the sclerotial exudates consisted of gallic, oxalic, ferulic, chlorogenic, and cinnamic acids, whereas the culture filtrate consisted of gallic, oxalic, and cinnamic acids along with many other unidentified compounds.Key words: oxalic acid, phenolic acid, salicylic acid, sclerotial exudate, culture filtrate, Sclerotium rolfsii, sclerotial germination.
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Iman Tagelsir Abdalla Mohamed, Wasim Khan, Karishma Chester, Abdelwahab Hassan Mohamed, Sayeed Ahmad, and Saad Mohamed Hussien Ayoub. "Simultaneous quantitative estimation of ellagic acid and gallic acid in Sudanese Solanum dubium seed by high performance thin layer chromatography (HPTLC)." GSC Biological and Pharmaceutical Sciences 13, no. 1 (October 30, 2020): 054–61. http://dx.doi.org/10.30574/gscbps.2020.13.1.0311.

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Background: Solanum dubium is a plant believed to have several therapeutic effects including anti-asthmatic properties. The objective of this study was to investigate the quantitative estimation of Gallic acid and Ellagic acid from the seed extract of Sudanese Solanum dubium. Methods: A simple and rapid high-performance thin-layer chromatographic method was developed and validated for quantitative estimation of Gallic acid and Ellagic acid from the seed extract of Sudanese Solanum dubium. Results: Ellagic acid and Gallic acid were quantified by using HPTLC. The seeds were found to contain 1.1% w/w of Ellagic acid and 2.1% w/w of Gallic acid in extract. Gallic acid and Ellagic acid were chromatographed on silica gel 60 F254 TLC plate using Toluene: Ethyl acetate – Methanol – Formic acid (3:3:1:0.4 v/v/v/v) as mobile phase and quantified by densitometric scanning at 280 nm. The method was found to give compact spots for Gallic acid (Rf 0.35) and Ellagic acid (Rf 0.21). The linear regression analysis data for standard Gallic and Ellagic acids spots showed good linear relationship with r2 = 0.988 and 0.994 respectively, in the concentration range 100-3000 ng/spot, accurate (99.23-102.7%), (98.7-100.2%); precise (% RSD ≤ 2); robust (% RSD ≤ 2) and specific. The LOD and LOQ of the method were found as 653 and 396.8ng/spot and 215.5and 130 ng/spot, of Gallic acid and Ellagic acid respectively. Conclusion: The method was validated for precision, recovery and repeatability as per the International Conference on Harmonization Guidelines for Gallic acid and Ellagic acid. Statistical analysis of the data showed that the method is precise, accurate, reproducible and selective for the analysis of Gallic acid and Ellagic acid.
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Dong, Fu-Yue, Jie Wu, Hai-Yan Tian, Qing-Mei Ye, and Ren-Wang Jiang. "Gallic acid pyridine monosolvate." Acta Crystallographica Section E Structure Reports Online 67, no. 11 (October 29, 2011): o3096. http://dx.doi.org/10.1107/s1600536811043868.

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Weetal, Howard H. "Enzymatic gallic acid esterification." Biotechnology and Bioengineering 27, no. 2 (February 1985): 124–27. http://dx.doi.org/10.1002/bit.260270203.

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Dissertations / Theses on the topic "Gallic acid"

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Wagh, Shilpa A. "Bioconversion of tannic acid to gallic acid by using fungal tannase." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2010. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3759.

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Chan, Shin Yee. "Biomarkers of tea and coffee-derived polyphenol exposure in human subjects." University of Western Australia. School of Medicine and Pharmacology, 2004. http://theses.library.uwa.edu.au/adt-WU2004.0046.

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Tea and coffee are rich in polyphenols with a variety of biological activities. Polyphenols found in tea are predominantly flavonoids, of which up to 15% are present as free or esterified gallic acid. Coffee polyphenols are almost wholly comprised of chlorogenic acids. Many of the demonstrated activities of polyphenols are consistent with favourable effects on the risk of chronic diseases. In investigating the relationships between intake and exposure to such compounds and chronic disease-related endpoints, it is important to be able to identify biomarkers that are specific to the compounds of interest. 4-O-methyl gallic acid (4OMGA) and isoferulic acid have been identified as potential biomarkers of intake and exposure to polyphenols derived from tea and coffee, respectively. 4OMGA is derived from gallic acid in tea, and isoferulic acid from chlorogenic acid in coffee. The major objectives of the research which is the subject of this thesis were (1) to establish a dose-response relationship of 24h urinary excretions of 4OMGA and isoferulic acid following ingestions of black tea and coffee of different strengths, and (2) to explore relationships of tea and coffee intake with 24h urinary excretion of 4OMGA and isoferulic acid in human populations. It was found that there was rapid excretion of both 4OMGA and isoferulic acid in the first 6h after tea and coffee ingestion, respectively. Approximately 60 80% of the ingested dose was excreted during the first 6h after ingestion. Urinary excretion of 4OMGA and isoferulic acid was directly related to the dose of tea and coffee, respectively. That is, higher intake resulted in increased urinary excretion of the metabolites. The relationships of 24h urinary excretion of 4OMGA and isoferulic acid with long-term usual (111 participants) and contemporary recorded current (344 participants) tea and coffee intake were assessed. 4OMGA was strongly related to usual (r = 0.50, P < 0.001) and current (r = 0.57, P < 0.001) tea intake. Isoferulic acid was less strongly, but significantly associated with usual (r = 0.26, P = 0.008) and current (r = 0.18, P < 0.001) coffee intake. Overall, the results are consistent with the proposal that 4OMGA is a good biomarker for black tea derived polyphenol intake and exposure, but isoferulic acid may have only limited use as a biomarker for coffee-derived polyphenol exposure.
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Menzi, Pateka. "Gallic acid modulates salt stress tolerance in soybean plants by regulating antioxidant capacity." University of the Western Cape, 2017. http://hdl.handle.net/11394/5905.

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Magister Scientiae - MSc (Biotechnology)
Soybean [Glycine max L (mer)] is one of the top commodity crops in the world including South Africa (de Beer and Prinsloo, 2013). These small yet important podded legumes are a great source of protein and are used in many forms.
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Yu, Kyle K. "Study of Copper Electrodeposition on Ruthenium Oxide Surfaces and Bimetallic Corrosion of Copper/Ruthenium in Gallic Acid Solution." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc3897/.

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Ruthenium, proposed as a new candidate of diffusion barrier, has three different kinds of oxides, which are native oxide, electrochemical reversible oxide and electrochemical irreversible oxide. Native oxide was formed by naturally exposed to air. Electrochemical reversible oxide was formed at lower anodic potential region, and irreversible oxides were formed at higher anodic potential region. In this study, we were focusing on the effect of copper electrodeposition on each type of oxides. From decreased charge of anodic stripping peaks and underpotential deposition (UPD) waves in cyclic voltammetry (CV), efficiency of Cu deposition dropped off indicating that interfacial binding strength between Cu and Ru oxides was weakened when the Ru surface was covered with irreversible oxide and native oxide. Also, Cu UPD was hindered by both O2 and H2 plasma modified Ru surfaces because the binding strength between Cu and Ru was weakened by O2 and H2 plasma treatment. Cu/Ru and Cu/Ta bimetallic corrosion was studied for understanding the corrosion behavior between diffusion barrier (Ta and Ru) and Cu interconnects under the post chemical mechanical planarization (CMP) process in semiconductor fabrication. Gallic acid is used in post CMP slurry solution and is known well as antioxidant which is supposed to oxidize itself to prevent other species from oxidizing. However, in this study under the observation of Cu microdot corrosion test, copper was corroded only in gallic acid at specific pH region of alkaline condition which is close to the pH region for post CMP solution formula. With different pH alkaline condition, gallic acid formed different oxidized products which are characterized by cyclic voltammetry and UV-Vis spectroscopy. Therefore, the specific oxidized product from particular pH region condition caused the Cu corrosion. Also, the corrosion rate of Cu microdots was influenced by substrate effect (Cu/Ru and Cu/Ta) and ambient control, which was included in this study.
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Dogan, Tunca. "The Effects Of Hydrogen Peroxide, Gallic Acid And Resveratrol On Growth And Catalase Production Of Aspergillus Fumigatus." Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/12609281/index.pdf.

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The aim of this study was to analyze the effect of hydrogen peroxide and selected phenolic compounds on growth and catalase production of Aspergillus fumigatus. As a result of growing A. fumigatus at different temperatures it was observed that, growth and catalase production of this species were highest at 37 °
C. Catalase production was highest in the presence of 1 mM H2O2, yielding a significant 3 fold increase with respect to the control. Biomass was also increased by 1,44 fold with respect to the control sample. H2O2 increased catalase production possibly by inducing oxidative stress as biomass production significantly increased after the depletion of H2O2. Both gallic acid and trans-resveratrol significantly enhanced biomass generation of A. fumigatus (1,17 fold increase at 10 mM gallic acid and 1,45 fold increase at 3 mM resveratrol with respect to controls) and decreased extracellular catalase production (4,33 fold at 25 mM gallic acid and 16,7 fold decrease at 3 mM resveratrol with respect to controls) especially in the first 5 or 6 days of the cultivation where the anti-oxidant activity of the compounds were possibly at their maximum. A sudden and significant rise was observed in extracellular catalase activity between 5th and 7th days of the cultivation in phenolic compound applied samples, possibly owing to the depletion of the antioxidant activity of gallic acid and resveratrol followed by fungal cells&rsquo
response to a sudden increase of oxidative stress by boosting catalase production.
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Muir, Ryann Morgan. "Analysis of gallic acid production by the bi-functional enzyme shikimate-5-dehydrogenase in higher plants and bacteria /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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Yu, Kyle K. Chyan Oliver Ming-Ren. "Study of copper electrodeposition on ruthenium oxide surfaces and bimetallic corrosion of copper/ruthenium in gallic acid solution." [Denton, Tex.] : University of North Texas, 2007. http://digital.library.unt.edu/permalink/meta-dc-3897.

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Mohamed, Gadija. "The effects of gallic acid on the membrane proteome and antioxidant system of wheat plants under salt stress." University of Western Cape, 2020. http://hdl.handle.net/11394/8252.

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>Magister Scientiae - MSc
Salt stress is a major abiotic stress that accounts for huge agricultural losses worldwide, which in turn threaten food security and sustainable agriculture. Salt triggers the excessive production of reactive oxygen species (ROS) which accumulate to levels that become toxic to plants, resulting in cell death and reduced plant growth. Part of the plant’s mechanisms to counteract ROS-induced cell death involves the scavenging ability of the antioxidant defense system to maintain redox homeostasis. Gallic acid (GA) is an antioxidant that has been shown to reduce salt-induced ROS in legume plants. However, its effects on wheat plants have not been elucidated. This study thus investigated the role of exogenous GA (250 μM) on the physiological responses and antioxidant system of wheat plants under salt stress (150 mM). In addition, this study also investigated how GA and salt stress influenced changes in the membrane proteome of wheat plants using LC-MS proteomic analysis.
2022
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Barbosa, Vanessa de Frias [UNESP]. "Caracterização do perfil da ação do ácido gálico e seus derivados sobre processos oxidativos in vitro e ex vivo." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/87981.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Compostos fenólicos são conhecidos por possuírem propriedades antioxidantes que influenciam na qualidade dos alimentos. O ácido gálico e seus derivados apresentam propriedades antioxidantes, antimicrobiana e propriedades antimutagênicas. Neste trabalho avaliamos a ação desses compostos sobre processos oxidativos in vitro e ex vivo sendo: i) Modelos químicos na supressão de formas oxidantes de ABTS +, DPPH HOCl, H2O2, O2 -, NO e taurina cloramina; ii) Sistemas enzimáticos como HRP e MPO; iii) Sistemas celulares com polimorfonucleares e eritrócitos frente a AAPH e HOCl. Os ensaios envolvendo as espécies oxidativas na presença de ácido gálico e derivados mostraram uma boa inibição, sendo que a amostras triacetato de ácido gálico mostrou ser a melhor das amostras testadas. Em relação aos sistemas enzimáticos os dados indicam inibição não competitiva ou mista. Nos sistemas celulares foi observado: i) citotoxicidade frente às células eritrocitárias e aos polimorfonucleares, ii) a amostra galato de isopropila demonstrou menor citotoxicidade frente aos eritrócitos, iii) a amostra galato de butila foi a que apresentou relativamente menor citotoxicidade chegando a 80% de morte celular, e iv) as outras amostras chegavam a 100% de morte celular na mesma concentração. Pelos dados obtidos, concluiu-se que o ácido gálico e seus derivados são potentes antioxidantes e inibidores das peroxidases HRP (Horseradish peroxidase) e MPO (mieloperoxidase), e com alta citotoxidade frente aos sistemas celulares estudados
Phenolic compounds are known to have antioxidant properties that influence the quality of food. Gallic acid and its derivatives have antioxidant, antimicrobial and antimutagenic properties. In this study the action of these compounds on oxidative processes in vitro and ex vivo which: i) Models in the suppression of chemical forms of oxidizing ABTS•+, DPPH• HOCl, H2O2, O2 •-, NO• and taurine chloramine ii) Enzymatic systems HRP and MPO iii) cellular systems with polymorphonuclear cells and erythrocytes against AAPH and HOCl. Tests involving the oxidative species in the presence of gallic acid and its derivatives showed good inhibition, and the triacetate samples of gallic acid were found to be the best of the tested samples. Regarding enzyme systems data indicate non-competitive or mixed inhibition. In cellular systems were observed: i) cytotoxicity against cells to erythrocyte and polymorphonuclear ii) the sample with erythrocytes the isopropyl gallate showed less cytotoxicity compared to the others samples, iii) the sample of butyl gallate showed the relatively lower cytotoxicity reaching 80% of cell death, and iv) the other specimens came to 100% cell death at the same concentration. From the data obtained showed that the gallic acid and its derivatives are potent antioxidants and inhibitors of peroxidases HRP (horseradish peroxidase) and MPO (myeloperoxidase), and high cytotoxicity against the cell systems studied
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Silva, Ana Carolina Alves de Paula e. [UNESP]. "Avaliação por métodos fenotípicos e proteômicos de galatos de alquila com atividade anti-complexo Paracoccidioides." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/91615.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Universidade Estadual Paulista (UNESP)
Paracoccidioides brasiliensis e P. lutzii são fungos dimórficos, agentes etiológicos da paracoccidioidomicose, que é uma micose humana sistêmica geograficamente confinada na América Latina. Vários antifúngicos podem ser utilizados para o tratamento dessa doença, tais como anfotericina B, sulfamídicos e azólicos (itraconazol) e de maneira geral seu uso é prolongado. As limitações frequentes dos antifúngicos e o aumento na incidência das infecções fúngicas sistêmicas têm ressaltado a necessidade da descoberta e do desenvolvimento de novos fármacos. O objetivo deste estudo foi comparar a atividade antifúngica de anfotericina B, itraconazol e galatos de alquila anti-complexo de Paracoccidioides por métodos fenotípicos e proteômicos. Para tanto foi padronizado o teste de sensibilidade para selecionar o galato de maior potência, utilizando o documento M27-A2 (2002), modificado pela adição de Alamar Blue. Adicionalmente, análises proteômicas foram realizadas antes e após tratamento com o antifúngico selecionado para verificar o perfil das possíveis proteínas-alvo. A atividade antifúngica foi estudada contra isolados de P. brasiliensis (S1, S2 e PS3) e P. lutzii, (Pb01-like), e depois o teste foi estendido para mais seis isolados. O valor da CIM do ácido gálico variou de 31,25 a 0,250 mg/L para todos os isolados. Os galatos mostraram valores de CIM entre 16 a 0,004 mg/L. O menor valor de CIM foi observado para seis galatos que possuem uma substituição por uma cadeia relativamente longa de carbonos. O perfil proteico dos isolados Pl01 e Pb18 foi estudado por eletroforese 2D após contato com anfotericina B , itraconazol e o galato de decila (todos a uma concentração de 0,125 mg/L. Mais de 130 spots para ambos os fungos foram observados e a maioria destas proteínas...
Paracoccidioides brasiliensis and P. lutzii are dimorphic fungi, etiological agents of paracoccidioidomycosis, which is a systemic human mycosis geographically restricted to Latin America. Various antifungal agents may be used to treat this disease, such as amphotericin B, sulfamidic agents and itraconazole, and these drugs are used in long-term therapies. The limitations of antifungals and increased incidence of systemic fungal infections has underscored the need for discovery and development of new drugs. The objective of this study was to compare the antifungal activity of amphotericin B, itraconazole and alkyl gallates anti-Paracoccidioides complex by phenotypic and proteomic methods. Thus, the susceptibility test was applied to select the most potent gallate, using the document M27-A2 (2002), modified by the addition of Alamar Blue. Finally, proteomic analyses was developed before and after the treatment with the antifungal agent selected, to study the protein profile after this treatment. The antifungal activity was evaluated against isolates of P. brasiliensis (S1, S2 and PS3) and P. lutzii (PB01-like), and after, the test has been extended to six isolates. The MIC values of gallic acid varied from 31.25 to 0.250 mg/L for all isolates. The gallates showed MIC values ranging from 16 to 0,004 mg/L. The lowest MIC value was observed for six gallates bearing a substitution for a long side chain. The protein profile of isolates Pb18 and Pl01 was studied by 2D electrophoresis after contact with amphotericin B, itraconazole and decyl gallate, all in the concentration of (0.125 mg/L ). More than 130 spots for both species were observed, and the most of these proteins... (Complete abstract click electronic access below)
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Books on the topic "Gallic acid"

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Shahrzad, Siranoush. Bestimmung bioaktiver Phenolcarbonsäuren in Säften und Weinen und Ermittlung der Metabolisierung und Biokinetik von Gallussäure beim Menschen. Marburg: Tectum Verlag, 1998.

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Handbook on Gallic Acid: Natural Occurrences, Antioxidant Properties and Health Implications. Nova Science Pub Inc, 2013.

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Murdoch, Jeff C. Chemistry of Gallic Acid and Its Role in Health and Disease. Nova Science Publishers, Incorporated, 2023.

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Extraction and Fermentation Process of Gallic Acid from Composition of Terminalia Species Leaves. GRIN Verlag GmbH, 2018.

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T. Mašek, Kristina Starčević, and Ž. Mikulec. The influence of the addition of thymol, tannic acid or gallic acid to broiler diet on growth performance, serum malondialdehyde value and cecal fermentation. Verlag Eugen Ulmer, 2014. http://dx.doi.org/10.1399/eps.2014.64.

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Book chapters on the topic "Gallic acid"

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Bährle-Rapp, Marina. "Gallic Acid." In Springer Lexikon Kosmetik und Körperpflege, 216. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_4154.

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van Lierop, Ben, Laurence Castle, Alexandre Feigenbaum, and Achim Boenke. "Gallic acid, propyl ester." In Spectra for the Identification of Additives in Food Packaging, 190–94. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5222-8_37.

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Haslam, Edwin. "Gallic Acid and Its Metabolites." In Plant Polyphenols, 169–94. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3476-1_10.

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Haslam, Edwin. "Hydroxybenzoic Acids and the Enigma of Gallic Acid." In The Shikimic Acid Pathway, 163–200. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-8056-6_7.

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Haslam, E. "Gallic Acid Derivatives and Hydrolyzable Tannins." In Natural Products of Woody Plants, 399–438. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74075-6_13.

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Perchellet, Jean-Pierre, Hala U. Gali, Elisabeth M. Perchellet, Darren S. Klish, and Andrew D. Armbrust. "Antitumor-Promoting Activities of Tannic Acid, Ellagic Acid, and Several Gallic Acid Derivatives in Mouse Skin." In Plant Polyphenols, 783–801. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3476-1_47.

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Dhiman, Sunny, and Gunjan Mukherjee. "Gallic Acid (GA): A Multifaceted Biomolecule Transmuting the Biotechnology Era." In Recent Developments in Microbial Technologies, 163–202. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4439-2_8.

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Farhan, Mohd, Mohammad Aatif, Sheikh Mumtaz Hadi, and Aamir Ahmad. "Mechanism of Gallic Acid Anticancer Activity Through Copper Mediated Cell Death." In Handbook of Oxidative Stress in Cancer: Mechanistic Aspects, 1–12. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-4501-6_179-1.

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Farhan, Mohd, Mohammad Aatif, Sheikh Mumtaz Hadi, and Aamir Ahmad. "Mechanism of Gallic Acid Anticancer Activity Through Copper-Mediated Cell Death." In Handbook of Oxidative Stress in Cancer: Mechanistic Aspects, 2559–70. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-15-9411-3_179.

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Werner, Ingo, Adelbert Bacher, and Wolfgang Eisenreich. "Analysis of Gallic Acid Biosynthesis via Quantitative Prediction of Isotope Labeling Patterns." In Plant Polyphenols 2, 43–61. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4139-4_3.

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Conference papers on the topic "Gallic acid"

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Wu, Meng, Guozhong Zhao, Haiyan Wang, and Chengshen Liang. "Terahertz spectrum of gallic acid." In International Conference on Optical Instrumentation and Technology, edited by Cunlin Zhang and Tiegen Liu. SPIE, 2009. http://dx.doi.org/10.1117/12.837432.

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Branković, Jovica, Vesna Milovanović, Zorica D. Petrović, and Vladimir P. Petrović. "GALLIC ACID HYDRAZONES: ‘IN SILICO’ INHIBITION OF THIOREDOXIN REDUCTASE." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.320b.

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Gallic hydrazones, as gallic acid derivatives, are known as pharmacophores of numerous multipotent agents. Among them, antiproliferative activity is one of the most important. On the other hand, thioredoxin reductase (TrxR1) is a part of the thioredoxin system, one of the most important systems responsible for maintaining the redox equilibrium inside the cell. It is overexpressed in different forms of tumors. Bearing this in mind, TrxR1 is a valid target for the development of compounds with potential antiproliferative activity. For this purpose, eight gallic acid-based hydrazones are selected and examined in silico for their potential inhibitory activity towards TrxR1.
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Radovic, Anna Z., Karolyne N. Stimpson, Igor P. Prikhodko, and JD Swanson. "Can Gallic Acid Reform Gastric Cancer Cells?" In 2019 IEEE SENSORS. IEEE, 2019. http://dx.doi.org/10.1109/sensors43011.2019.8956810.

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Dorovic, Jelena R., Dejan A. Milenkovic, and Zoran S. Markovic. "Study of electron transfer mechanism of gallic acid." In 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering (BIBE). IEEE, 2015. http://dx.doi.org/10.1109/bibe.2015.7367649.

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Malinda, Krissan, Hery Sutanto, and Akhmad Darmawan. "Characterization and antioxidant activity of gallic acid derivative." In PROCEEDINGS OF THE 3RD INTERNATIONAL SYMPOSIUM ON APPLIED CHEMISTRY 2017. Author(s), 2017. http://dx.doi.org/10.1063/1.5011887.

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Petrovic, Aleksandar, Nikolina Lisov, Ivana Plavsic-Janjatovic, Ivana Sredovic-Ignjatovic, and Danka Mitrovic. "THE INFLUENCE OF THE ENOLOGICAL TANNINS APPLICATION ON THE PHENOLIC COMPOSITION OF WINE." In 1st INTERNATIONAL SYMPOSIUM ON BIOTECHNOLOGY. University of Kragujevac, Faculty of Agronomy, 2023. http://dx.doi.org/10.46793/sbt28.523p.

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The chemical composition of wine depends on the degree of maturity and quality of the grapes, as well as the agroecological conditions under which the grapes are grown. Tannins are of particular importance for wines, they are the source of the characteristic astringency of red wines. The main aim of this study was to investigate the influence of addition of enological tannins (0.05 g/L; 0.15 g/L; 0.3 g/L) on the phenolic composition of wine. The effect of the addition of differenttannins on the certain phenolic compounds (gallic acid, caffeic acid, ellagic acid and quercetin) was measured by HPLC analysis.Only forcontent of gallic and caffeic acid, there was a statistically significant difference between the control sample and all other samples with added tannins.
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Rodriguez-Fragoso, Lourdes, Erick Ayala-Calvillo, and Felipe Rodríguez-López. "Gallic acid modifies EGFR phosphorylation in rat with hepatic preneoplasia." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.170520.

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Firdaus, Radhinal Zikri, Sri Handayani, Tuti Wukirsari, and Sumi Hudiyono. "Synthesis and antibacterial activity of phenolipid methyl dihydroxystearate-gallic acid." In PROCEEDINGS OF THE 4TH INTERNATIONAL CONFERENCE ON CHEMICAL PROCESSING AND ENGINEERING (4th IC3PE). AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0204843.

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Dumbrava, Delia-Gabriela, Cristian-Alin Costescu, Diana-Nicoleta Raba, Viorica-Mirela Popa, and Camelia Moldovan. "ANTIOXIDANT, NUTRITIONAL AND SENSORY CHARACTERISTICS OF TWO INNOVATIVE TYPES OF GLUTEN-FREE BREAD." In 22nd SGEM International Multidisciplinary Scientific GeoConference 2022. STEF92 Technology, 2022. http://dx.doi.org/10.5593/sgem2022v/6.2/s25.09.

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In recent years, because the gluten intolerance has become a worldwide problem, there were a sharp increase in the consumers demand for gluten-free bakery products that to be attractive, both in terms of sensory and nutritional value. This work had as a first goal obtaining of two innovative gluten-free bread types, one from almond flour, brown rice flour and psyllium bran (P1), and the second from buckwheat flour and psyllium bran (P2). A second aim of the paper was to determine total polyphenols (FolinCiocalteu method) and antioxidant activity (DPPH free radical assay) both for raw materials and finished products, as well as the proximate composition, energy value and sensory characteristics (hedonic scoring method from 1 to 5). Among the three types of flour, the almond one had the highest content of total polyphenols (334.28�0.59 mg gallic acid/g), followed by buckwheat flour (289.93�0.50 mg gallic acid/g). P1 bread was richer in total polyphenols (134.35�0.10 mg gallic acid/g) than P2 (128.99�0.05 mg gallic acid/g). The 1:10 ethanolic extract from almond flour had a higher DPPH free radical scavenging activity (86.98�0.47 %) than the extracts from buckwheat flour, respectively from whole brown rice flour (84.71�0.19 %, respectively 84.61�0.29 %). Bread P1 also had a higher DPPH free radical scavenging activity (79.49�0.28 %) than P2 (69,73�0,04 %). From a nutritional point of view, bread P1 had a higher energy value (265.68 kcal/100g), having a richer content of total lipids, proteins and carbohydrates than bread P2 (191.51 kcal/100g). Both types of bread were evaluated with good scores in all the organoleptic characteristics analyzed by the tasters.
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Zhang, Xin, Sara Ferraris, Enrica Verné, Alberto Venturello, and Enrico Prenesti. "Surface Functionalization of Bioactive and Ferrimagnetic Glass-Ceramics (SC45) with Gallic Acid and Folic Acid." In Biomedical Engineering. Calgary,AB,Canada: ACTAPRESS, 2013. http://dx.doi.org/10.2316/p.2013.791-168.

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Reports on the topic "Gallic acid"

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Williams, D. F. Lewis-Acid/Base Effects on Gallium Volatility in Molten Chlorides. Office of Scientific and Technical Information (OSTI), February 2001. http://dx.doi.org/10.2172/777695.

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Sengupta-Gopalan, Champa, Shmuel Galili, and Rachel Amir. Improving Methionine Content in Transgenic Forage Legumes. United States Department of Agriculture, February 2001. http://dx.doi.org/10.32747/2001.7580671.bard.

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Leguminous forage crops are high in proteins but deficient in S- amino acids. It has been shown that both wool quality and milk production can be limited by the post-ruminal supply of sulfur-containing amino acids. Efforts to use conventional plant breeding and cell selection techniques to increase the S-amino acid content of alfalfa have met with little success. With the objective to increase the S-amino acid content of forage legumes, the goal of this project was to co- express the methionine rich zein genes from corn along with a gene for a key enzyme in methionine biosynthesis, aspartate kinase(AK). The zeins are seed storage proteins from corn and are groupec into four distinct classes based on their amino acid sequence homologies. The b-zein (15kd) and the 6zein (10kD and 18kD) have proportionately high levels of methionine (10%, 22% and 28%, respectively). Initial studies from our lab had shown that while the 15kD zein accumulated to high levels in vegetative tissues of transgenic tobacco the l0kD zein did not. However, co-expression of the 10kD zein with the 15kD zein genes in tobacco showed stabilization of the 10kD zein and the co-localization of the 10kD and 15kD zein proteins in unique ER derived protein bodies. AK is the key enzyme for producing carbon skeletons for all amino acids of the aspartate family including methionine. It is, however, regulated by end-product feedback inhibition. The specific objectives of this proposal were: i. to co-express the 15kD zein with the 10/18kD zein genes in alfalfa in order to enhance the level of accumulation of the 10/18kD zein; ii. to increase methionine pools by expressing a feedback insensitive AK gene in transformants co-expressing the 15kD and 10/18kD zein genes. The Israeli partners were successful in expressing the AK gene in alfalfa which resulted in an increase in free and bound threonine but not in methionine (Galili et al., 2000). Since our target was to increase methionine pools, we changed our second objective to replace the AK gene with the gene for cystathionine gamma synthase (CGS) in the co-expression studies. The first methionine specific reaction is catalyzed by CGS. An additional objective was to develop a transformation system for Berseem clover, and to introduce the appropriate gene constructs into it with the goal of improving their methionine content. Genes for the 15kD zein along with the genes for either the 10kD or 18kD zein have been introduced into the same alfalfa plant both by sexual crosses and by re-transformation. Analysis of these zein co-expressors have shown that both the IOkD and 18kD zein levels go up 5 to 10 fold when co-expressed with the 15kD zein (Bagga et al., MS in preparation). Incubation of the leaves of transgenic alfalfa co-expressing the 15kD and 10kD zein genes, in the rumen of cows have shown that the zein proteins are stable in the rumen. To increase the level of zein accumulation in transgenic alfalfa different promoters have been used to drive the zein genes in alfalfa and we have concluded that the CaMV 35S promoter is superior to the other strong leaf -specific promoters. By feeding callus tissue of alfalfa plants co-expressing the 15kD and 10kD zein genes with methionine and its precursors, we have shown that the zein levels could be significantly enhanced by increasing the methionine pools. We have now introduced the CGS gene (from Arabidopsis; kindly provided to us by Dr. Leustek), into the 15kD zein transformants and experiments are in progress to check if the expression of the CGS gene indeed increases the level of zein accumulation in alfalfa. We were not successful in developing a transformation protocol for Berseem clover.
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Jander, Georg, Gad Galili, and Yair Shachar-Hill. Genetic, Genomic and Biochemical Analysis of Arabidopsis Threonine Aldolase and Associated Molecular and Metabolic Networks. United States Department of Agriculture, January 2010. http://dx.doi.org/10.32747/2010.7696546.bard.

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Since the amino acids threonine and isoleucine can be limiting in mammalian diet and there is interest in increasing their abundance in certain crop plants. To meet this need, a BARD proposal was written with two main research objectives: (i) investigate new avenues for manipulating threonine and isoleucine content in plants and (ii) study the role of threonine aldolase in plant metabolism. Research conducted to meet these goals included analysis of the sub-cellular localization of threonine aldolase in the plant, analysis of metabolic flux in developing embryos, over- and under-expression of Arabidopsis threonine aldolases, and transcriptional and metabolic analysis of perturbations resulting from altered threonine aldolase expression. Additionally, the broader metabolic effects of increasing lysine biosynthesis were investigated. An interesting observation that came up in the course of the project is that threonine aldolase activity affects methionine gamma-lyase in Arabidopsis. Further research showed that threonine deaminase and methionine gamma-lyase both contribute to isoleucine biosynthesis in plants. Therefore, isoleucine content can be altered by manipulating the expression of either or both of these enzymes. Additionally, both enzymes contribute to the up to 100-fold increase in isoleucine that is observed in drought-stressed Arabidopsis. Toward the end of the project it was discovered that through different projects, both groups had been able to independently up-regulate phenylalanine accumulation by different mechanisms. The Galili lab transformed Arabidopsis with a feedbackinsensitive bacterial enzyme and the Jander lab found a feedback insensitive mutation in Arabidopsis arogenate dehydratase. Exchange of the respective plant lines has allowed a comparative analysis of the different methods for increasing phenylalanine content and the creation of double mutants. The research that was conducted as part of this BARD project has led to new insights into plant amino acid metabolism. Additionally, new approaches that were found to increase the accumulation of threonine, isoleucine, and phenylalanine in plants have potential practical applications. Increased threonine and isoleucine levels can increase the nutritional value of crop plants. Elevated isoleucine accumulation may increase the osmotic stress tolerance of plants. Up-regulation of phenylalanine biosynthesis can be used to increase the production of downstream higher-value plant metabolites of biofuel feed stocks.
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Ron, Eliora, and Eugene Eugene Nester. Global functional genomics of plant cell transformation by agrobacterium. United States Department of Agriculture, March 2009. http://dx.doi.org/10.32747/2009.7695860.bard.

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The aim of this study was to carry out a global functional genomics analysis of plant cell transformation by Agrobacterium in order to define and characterize the physiology of Agrobacterium in the acidic environment of a wounded plant. We planed to study the proteome and transcriptome of Agrobacterium in response to a change in pH, from 7.2 to 5.5 and identify genes and circuits directly involved in this change. Bacteria-plant interactions involve a large number of global regulatory systems, which are essential for protection against new stressful conditions. The interaction of bacteria with their hosts has been previously studied by genetic-physiological methods. We wanted to make use of the new capabilities to study these interactions on a global scale, using transcription analysis (transcriptomics, microarrays) and proteomics (2D gel electrophoresis and mass spectrometry). The results provided extensive data on the functional genomics under conditions that partially mimic plant infection and – in addition - revealed some surprising and significant data. Thus, we identified the genes whose expression is modulated when Agrobacterium is grown under the acidic conditions found in the rhizosphere (pH 5.5), an essential environmental factor in Agrobacterium – plant interactions essential for induction of the virulence program by plant signal molecules. Among the 45 genes whose expression was significantly elevated, of special interest is the two-component chromosomally encoded system, ChvG/I which is involved in regulating acid inducible genes. A second exciting system under acid and ChvG/Icontrol is a secretion system for proteins, T6SS, encoded by 14 genes which appears to be important for Rhizobium leguminosarum nodule formation and nitrogen fixation and for virulence of Agrobacterium. The proteome analysis revealed that gamma aminobutyric acid (GABA), a metabolite secreted by wounded plants, induces the synthesis of an Agrobacterium lactonase which degrades the quorum sensing signal, N-acyl homoserine lactone (AHL), resulting in attenuation of virulence. In addition, through a transcriptomic analysis of Agrobacterium growing at the pH of the rhizosphere (pH=5.5), we demonstrated that salicylic acid (SA) a well-studied plant signal molecule important in plant defense, attenuates Agrobacterium virulence in two distinct ways - by down regulating the synthesis of the virulence (vir) genes required for the processing and transfer of the T-DNA and by inducing the same lactonase, which in turn degrades the AHL. Thus, GABA and SA with different molecular structures, induce the expression of these same genes. The identification of genes whose expression is modulated by conditions that mimic plant infection, as well as the identification of regulatory molecules that help control the early stages of infection, advance our understanding of this complex bacterial-plant interaction and has immediate potential applications to modify it. We expect that the data generated by our research will be used to develop novel strategies for the control of crown gall disease. Moreover, these results will also provide the basis for future biotechnological approaches that will use genetic manipulations to improve bacterial-plant interactions, leading to more efficient DNA transfer to recalcitrant plants and robust symbiosis. These advances will, in turn, contribute to plant protection by introducing genes for resistance against other bacteria, pests and environmental stress.
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Alfano, James, Isaac Barash, Thomas Clemente, Paul E. Staswick, Guido Sessa, and Shulamit Manulis. Elucidating the Functions of Type III Effectors from Necrogenic and Tumorigenic Bacterial Pathogens. United States Department of Agriculture, January 2010. http://dx.doi.org/10.32747/2010.7592638.bard.

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Many phytopathogenic bacteria use a type III protein secretion system (T3SS) to inject type III effectors into plant cells. In the experiments supported by this one-year feasibility study we investigated type III effector function in plants by using two contrasting bacterial pathogens: Pseudomonas syringae pv. tomato, a necrotrophic pathogen and Pantoea agglomerans, a tumorigenic pathogen. The objectives are listed below along with our major conclusions, achievements, and implications for science and agriculture. Objective 1: Compare Pseudomonas syringae and Pantoea agglomerans type III effectors in established assays to test the extent that they can suppress innate immunity and incite tumorigenesis. We tested P. agglomerans type III effectors in several innate immunity suppression assays and in several instances these effectors were capable of suppressing plant immunity, outputs that are suppressed by P. syringae effectors. Interestingly, several P. syringae effectors were able to complement gall production to a P. agglomerans pthGmutant. These results suggest that even though the disease symptoms of these pathogens are dramatically different, their type III effectors may function similarly. Objective 2: Construct P. syringae mutants in different combinations of type III-related DNA clusters to reduce type III effector redundancy. To determine their involvement in pathogenicity we constructed mutants that lack individual and multiple type III-related DNA clusters using a Flprecombinase-mediated mutagenesis strategy. The majority of single effector mutants in DC3000 have weak pathogenicity phenotypes most likely due to functional redundancy of effectors. Supporting this idea, Poly-DNAcluster deletion mutants were more significantly reduced in their ability to cause disease. Because these mutants have less functional redundancy of type III effectors, they should help identify P. syringae and P. agglomerans effectors that contribute more significantly to virulence. Objective 3: Determine the extent that P. syringae and P. agglomerans type III effectors alter hormone levels in plants. Inhibition of auxin polar transport by 2,3,5-triiodobenzoic acid (TIBA) completely prevented gall formation by P. agglomerans pv. gypsophilae in gypsophila cuttings. This result supported the hypothesis that auxin and presumably cytokinins of plant origin, rather than the IAA and cytokinins secreted by the pathogen, are mandatory for gall formation. Transgenic tobacco with pthGshowed various phenotypic traits that suggest manipulation of auxin metabolism. Moreover, the auxin levels in pthGtransgenic tobacco lines was 2-4 times higher than the control plants. External addition of auxin or cytokinins could modify the gall size in gypsophila cuttings inoculated with pthGmutant (PagMx27), but not with other type III effectors. We are currently determining hormone levels in transgenic plants expressing different type III effectors. Objective 4: Determine whether the P. agglomerans effectors HsvG/B act as transcriptional activators in plants. The P. agglomerans type III effectors HsvG and HsvB localize to the nucleus of host and nonhost plants and act as transcription activators in yeast. Three sites of adjacent arginine and lysine in HsvG and HsvB were suspected to act as Nuclear localization signals (NLS) domains. A nuclear import assay indicated two of the three putative NLS domains were functional NLSs in yeast. These were shown to be active in plants by fusing HsvG and HsvB to YFP. localization to the nucleus was dependent on these NLS domains. These achievements indicate that our research plan is feasible and suggest that type III effectors suppress innate immunity and modulate plant hormones. This information has the potential to be exploited to improve disease resistance in agricultural crops.
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Katzir, Nurit, James Giovannoni, Marla Binzel, Efraim Lewinsohn, Joseph Burger, and Arthur Schaffer. Genomic Approach to the Improvement of Fruit Quality in Melon (Cucumis melo) and Related Cucurbit Crops II: Functional Genomics. United States Department of Agriculture, January 2010. http://dx.doi.org/10.32747/2010.7592123.bard.

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Background: Genomics tools for enhancement of melon research, with an emphasis on fruit, were developed through a previous BARD project of the PIs (IS -333-02). These included the first public melon EST collection, a database to relay this information to the research community and a publicly available microarray. The current project (IS-3877- 06) aimed to apply these tools for identification of important genes for improvement of melon (Cucumis melo) fruit quality. Specifically, the research plans included expression analysis using the microarray and functional analyses of selected genes. The original project objectives, as they appeared in the approved project, were: Objective 1: Utilization of a public melon microarray developed under the existing project to characterize melon transcriptome activity during the ripening of normal melon fruit (cv. Galia) in order to provide a basis for both a general view of melon transcriptome activity during ripening and for comparison with existing transcriptome data of developing tomato and pepper fruit. Objective 2: Utilization of the same public melon microarray to characterize melon transcriptome activity in lines available in the collection of the Israeli group, focusing on sugar, organic acids and aroma metabolism, so as to identify potentially useful candidates for functional analysis and possible manipulation, through comparison with the general fruit development profile resulting from (1) above. Objective 3: Expansion of our existing melon EST database to include publicly available gene expression data and query tools, as the US group has done with tomato. Objective 4: Selection of 6-8 candidate genes for functional analysis and development of DNA constructs for repression or over-expression. Objective 5: Creation of transgenic melon lines, or transgenic heterologous systems (e.g. E. coli or tomato), to assess putative functions and potential as tools for molecular enhancement of melon fruit quality, using the candidate gene constructs from (4).
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