Journal articles on the topic 'G13D'
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Rojo, Federico, Trinidad Caldes, Sandra Zazo, Miguel de la Hoya, Cristina Carames, Atocha Romero, Gloria Serrano, et al. "Prevalence of low-penetrance KRAS (codons 12/13 and 61) and BRAF mutations in metastatic colorectal carcinoma." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): e14147-e14147. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e14147.
Full textRabara, Dana, Timothy H. Tran, Srisathiyanarayanan Dharmaiah, Robert M. Stephens, Frank McCormick, Dhirendra K. Simanshu, and Matthew Holderfield. "KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis." Proceedings of the National Academy of Sciences 116, no. 44 (October 14, 2019): 22122–31. http://dx.doi.org/10.1073/pnas.1908353116.
Full textLee, Hyo Joo, Bonhan Koo, Yoon Ok Jang, Huifang Liu, Thuy Nguyen Thi Dao, Seok-Byung Lim, and Yong Shin. "Hot-Spot-Specific Probe (HSSP) for Rapid and Accurate Detection of KRAS Mutations in Colorectal Cancer." Biosensors 12, no. 8 (August 4, 2022): 597. http://dx.doi.org/10.3390/bios12080597.
Full textLopez Ruitti, Paula, Ruben Salanova, Julieta Nafissi, Guillermo Rabossi, Guillermo Bramuglia, and Yanina Powazniak. "Mutational status of KRAS and BRAF of an Argentinian population of colorectal tumors." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): e14109-e14109. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e14109.
Full textYuan, Ye, Yingting Liu, Ye Wu, Junling Zhang, Chunti Shen, Feng Zhang, Changping Wu, and Wenwei Hu. "Clinical characteristics and prognostic value of the KRAS mutation in Chinese colorectal cancer patients." International Journal of Biological Markers 36, no. 2 (May 27, 2021): 33–39. http://dx.doi.org/10.1177/17246008211017152.
Full textAttoye, Bukola, Matthew Baker, Chantevy Pou, Fiona Thomson, and Damion K. Corrigan. "Electrochemical DNA Detection Methods to Measure Circulating Tumour DNA for Enhanced Diagnosis and Monitoring of Cancer." Proceedings 60, no. 1 (November 2, 2020): 15. http://dx.doi.org/10.3390/iecb2020-07067.
Full textSalem, Mohamed E., Scott Kopetz, Josep Tabernero, Frank A. Sinicrope, Myriam Chalabi, Jeanne Tie, Kunal C. Kadakia, et al. "Comprehensive characterization of KRAS mutations and inter-relation with primary tumor location in colorectal cancers." Journal of Clinical Oncology 41, no. 4_suppl (February 1, 2023): 231. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.231.
Full textTahir, Raiha, Santosh Renuse, Savita Udainiya, Anil K. Madugundu, Jevon A. Cutler, Raja Sekhar Nirujogi, Chan Hyun Na, Yaoyu Xu, Xinyan Wu, and Akhilesh Pandey. "Mutation-Specific and Common Phosphotyrosine Signatures of KRAS G12D and G13D Alleles." Journal of Proteome Research 20, no. 1 (September 28, 2020): 670–83. http://dx.doi.org/10.1021/acs.jproteome.0c00587.
Full textMusselwhite, Laura W., Sally J. Trufan, Kunal C. Kadakia, Jimmy J. Hwang, and Mohamed E. Salem. "The prevalence of common KRAS variants and associated outcomes in patients with metastatic colorectal cancer (mCRC)." Journal of Clinical Oncology 40, no. 4_suppl (February 1, 2022): 173. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.173.
Full textTejpar, Sabine, Ilhan Celik, Michael Schlichting, Ute Sartorius, Carsten Bokemeyer, and Eric Van Cutsem. "Association of KRAS G13D Tumor Mutations With Outcome in Patients With Metastatic Colorectal Cancer Treated With First-Line Chemotherapy With or Without Cetuximab." Journal of Clinical Oncology 30, no. 29 (October 10, 2012): 3570–77. http://dx.doi.org/10.1200/jco.2012.42.2592.
Full textAttoye, Bukola, Matthew J. Baker, Fiona Thomson, Chantevy Pou, and Damion K. Corrigan. "Optimisation of an Electrochemical DNA Sensor for Measuring KRAS G12D and G13D Point Mutations in Different Tumour Types." Biosensors 11, no. 2 (February 5, 2021): 42. http://dx.doi.org/10.3390/bios11020042.
Full textTejpar, S., C. Bokemeyer, I. Celik, M. Schlichting, and E. Van Cutsem. "The role of the KRAS G13D mutation in patients with metastatic colorectal cancer (mCRC) treated with first-line chemotherapy plus cetuximab." Journal of Clinical Oncology 29, no. 4_suppl (February 1, 2011): 630. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.630.
Full textTeo, Michelle Yee Mun, Jeremy Jeack Ceen Ng, Jung Yin Fong, Jung Shan Hwang, Adelene Ai-Lian Song, Renee Lay Hong Lim, and Lionel Lian Aun In. "Development of a single-chain fragment variable fused-mutant HALT-1 recombinant immunotoxin against G12V mutated KRAS colorectal cancer cells." PeerJ 9 (April 15, 2021): e11063. http://dx.doi.org/10.7717/peerj.11063.
Full textIiizumi, Susumu, Junya Ohtake, Naoko Murakami, Taku Kouro, Mamoru Kawahara, Fumiko Isoda, Hiroshi Hamana, Hiroyuki Kishi, Norihiro Nakamura, and Tetsuro Sasada. "Identification of Novel HLA Class II-Restricted Neoantigens Derived from Driver Mutations." Cancers 11, no. 2 (February 24, 2019): 266. http://dx.doi.org/10.3390/cancers11020266.
Full textShinozaki, Eiji, Yoshio Miki, Masashi Ueno, Masahiro Igarashi, Mitsukuni Suenaga, Keisho Chin, Masato Ozaka, et al. "Phenotypic differences among RAS mutational variations in colorectal cancer (CRC): Analysis of 1,001 patients in single institute." Journal of Clinical Oncology 33, no. 3_suppl (January 20, 2015): 649. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.649.
Full textTurner, Elizabeth, Luping Chen, John G. Foulke, Zhizhan Gu, and Fang Tian. "CRISPR/Cas9 Edited RAS & MEK Mutant Cells Acquire BRAF and MEK Inhibitor Resistance with MEK1 Q56P Restoring Sensitivity to MEK/BRAF Inhibitor Combo and KRAS G13D Gaining Sensitivity to Immunotherapy." Cancers 14, no. 21 (November 5, 2022): 5449. http://dx.doi.org/10.3390/cancers14215449.
Full textGuglielmini, Pamela Francesca, Maura Rossi, Federica Grosso, Sara Orecchia, Marco Galliano, Elisa Bennicelli, Silvia Zai, et al. "Double KRAS and BRAF mutations in colorectal cancer in a single oncologic department series." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): e14657-e14657. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e14657.
Full textAkiyoshi, Kohei, Yasuhide Yamada, Naoki Takahashi, Yoshitaka Honma, Satoru Iwasa, Ken Kato, Tetsuya Hamaguchi, and Yasuhiro Shimada. "The efficacy of antiepidermal growth factor receptor monoclonal antibodies for patients with KRAS G13D mutations and chemorefractory metastatic colorectal cancer." Journal of Clinical Oncology 30, no. 4_suppl (February 1, 2012): 527. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.527.
Full textSegelov, Eva, Kate Wilson, Val Gebski, Paul Michael Waring, Josep Tabernero, Harpreet Wasan, Fortunato Ciardiello, et al. "ICE CREAM: Irinotecan cetuximab evaluation and the cetuximab response evaluation among patients with G13D mutation." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): TPS3649. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.tps3649.
Full textSegelov, Eva, Subotheni Thavaneswaran, Paul M. Waring, Jayesh Desai, Kristy P. Robledo, Val J. Gebski, Elena Elez, et al. "Response to Cetuximab With or Without Irinotecan in Patients With Refractory Metastatic Colorectal Cancer Harboring the KRAS G13D Mutation: Australasian Gastro-Intestinal Trials Group ICECREAM Study." Journal of Clinical Oncology 34, no. 19 (July 1, 2016): 2258–64. http://dx.doi.org/10.1200/jco.2015.65.6843.
Full textJung, Jaeyun, Sehhoon Park, Jeeyun Lee, and Seung Kim. "Solid tumor patients with G12V and G13D KRAS aberrations have poor survival following ICI treatment." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): e14567-e14567. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e14567.
Full textJung, Jaeyun, Sehhoon Park, Jeeyun Lee, and Seung Kim. "Solid tumor patients with G12V and G13D KRAS aberrations have poor survival following ICI treatment." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): e14567-e14567. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e14567.
Full textSalih, Gaza Farag, and Shad Sudad. "ARMS-PCR based diagnosis of APCB and KRAS genes in colorectal cancer patients in Iraqi Sulaimania province." Journal of Solid Tumors 7, no. 1 (December 30, 2016): 27. http://dx.doi.org/10.5430/jst.v7n1p27.
Full textAcoba, Jared David, Christopher A. Lum, and Lambert T. Leong. "Analysis of KRAS and BRAF mutant colorectal cancers in a multiracial population." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 1599. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.1599.
Full textMaier, Attenberger, Tiwari, Lettau, Rebholz, Fehrenbacher, Schaller, Gani, and Toulany. "Dual Targeting of Y-Box Binding Protein-1 and Akt Inhibits Proliferation and Enhances the Chemosensitivity of Colorectal Cancer Cells." Cancers 11, no. 4 (April 19, 2019): 562. http://dx.doi.org/10.3390/cancers11040562.
Full textMalapelle, Umberto, Roberta Sgariglia, Alfonso De Stefano, Claudio Bellevicine, Elena Vigliar, Dario de Biase, Romina Sepe, et al. "KRAS Mutant Allele-Specific Imbalance (MASI) assessment in routine samples of patients with metastatic colorectal cancer." Journal of Clinical Pathology 68, no. 4 (January 21, 2015): 265–69. http://dx.doi.org/10.1136/jclinpath-2014-202761.
Full textGvaldin, Dmitry Yu, Oleg I. Kit, Ekaterina P. Omelchuk, Dmitry O. Kaymakchi, Sergey I. Poluektov, Dmitry Sergeevich Petrov, Vladimir E. Kolesnikov, and Liubov Yu Vladimirova. "Frequency of somatic mutations in the KRAS gene in patients of the South Russia diagnosed with colorectal cancer." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e15081-e15081. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e15081.
Full textLu, Jia, John Hunter, Anuj Manandhar, Deepak Gurbani, and Kenneth D. Westover. "Structural dataset for the fast-exchanging KRAS G13D." Data in Brief 5 (December 2015): 572–78. http://dx.doi.org/10.1016/j.dib.2015.10.001.
Full textBerger, Andreas W., Daniel Schwerdel, Hanna Welz, Thomas Jens Ettrich, Peter Moeller, and Thomas Seufferlein. "The occurrence of mutant KRAS clones in the blood of RAS wild type colorectal cancer patients: Impact of response or failure under anti-EGFR therapy." Journal of Clinical Oncology 34, no. 4_suppl (February 1, 2016): 600. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.600.
Full textYu, Zhiping, Hongyi Su, Jianzhong Chen, and Guodong Hu. "Deciphering Conformational Changes of the GDP-Bound NRAS Induced by Mutations G13D, Q61R, and C118S through Gaussian Accelerated Molecular Dynamic Simulations." Molecules 27, no. 17 (August 30, 2022): 5596. http://dx.doi.org/10.3390/molecules27175596.
Full textAdderley, Helen M., Mihaela Aldea, Jaqueline Aredo, Mathew Carter, Matthew Church, Pantelis Nicola, Jamie Weaver, et al. "Abstract 2975: RAS precision medicine transatlantic partnership: Exploration of RAS and NF1 co-mutations in NSCLC." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2975. http://dx.doi.org/10.1158/1538-7445.am2022-2975.
Full textNakamura, Masato, Toru Aoyama, Keiichiro Ishibashi, Akihito Tsuji, Yasutaka Takinishi, Yoshiaki Shindo, Junichi Sakamoto, Koji Oba, and Hideyuki Mishima. "Randomized phase II study of cetuximab versus irinotecan and cetuximab in patients with chemo-refractory KRAS codon G13D metastatic colorectal cancer (G13D-study)." Cancer Chemotherapy and Pharmacology 79, no. 1 (November 22, 2016): 29–36. http://dx.doi.org/10.1007/s00280-016-3203-7.
Full textDe Falco, Elena, Luca Pacini, Daniela Bastianelli, Gian Paolo Spinelli, Chiara Spoto, Enzo Veltri, and Antonella Calogero. "Concomitant Mutations G12D and G13D on the Exon 2 of the KRAS Gene: Two Cases of Women with Colon Adenocarcinoma." Diagnostics 11, no. 4 (April 6, 2021): 659. http://dx.doi.org/10.3390/diagnostics11040659.
Full textOkada, Satoshi, Keisuke Hata, Kazushige Kawai, Yoko Yamamoto, Toshiaki Tanaka, Takeshi Nishikawa, Kazuhito Sasaki, et al. "Association between KRAS G13D mutations and anastomotic recurrence in colorectal cancer." Medicine 98, no. 12 (March 2019): e14781. http://dx.doi.org/10.1097/md.0000000000014781.
Full textPeeters, Marc, Jean-Yves Douillard, Eric Van Cutsem, Salvatore Siena, Kathy Zhang, Richard Thomas Williams, and Jeffrey S. Wiezorek. "Mutant (MT) KRAS codon 12 and 13 alleles in patients (pts) with metastatic colorectal cancer (mCRC): Assessment as prognostic and predictive biomarkers of response to panitumumab (pmab)." Journal of Clinical Oncology 30, no. 4_suppl (February 1, 2012): 383. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.383.
Full textPeeters, Marc, Jean-Yves Douillard, Eric Van Cutsem, Salvatore Siena, Kathy Zhang, Richard Thomas Williams, and Jeffrey S. Wiezorek. "Mutant (MT) KRAS codon 12 and 13 alleles in patients (pts) with metastatic colorectal cancer (mCRC): Assessment as prognostic and predictive biomarkers of response to panitumumab (pmab)." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 3581. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.3581.
Full textIshibashi, Keiichiro, Masato Nakamura, Akihito Tsuji, Yasutaka Takinishi, Yoshiaki Shindo, Toru Aoyama, Junichi Sakamoto, Koji Oba, and Hideyuki Mishima. "Randomized phase II study of cetuximab vs. irinotecan and cetuximab in patients with chemo-refractory KRAS codon G13D metastatic colorectal cancer (G13D-study): Compared with ICECREAM study." Annals of Oncology 28 (June 2017): iii109—iii110. http://dx.doi.org/10.1093/annonc/mdx261.311.
Full textNtai, Ioanna, Luca Fornelli, Caroline J. DeHart, Josiah E. Hutton, Peter F. Doubleday, Richard D. LeDuc, Alexandra J. van Nispen, et al. "Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk." Proceedings of the National Academy of Sciences 115, no. 16 (April 2, 2018): 4140–45. http://dx.doi.org/10.1073/pnas.1716122115.
Full textAl-Turkmani, M. Rabie, Kelley N. Godwin, Jason D. Peterson, and Gregory J. Tsongalis. "Rapid Somatic Mutation Testing in Colorectal Cancer by Use of a Fully Automated System and Single-Use Cartridge: A Comparison with Next-Generation Sequencing." Journal of Applied Laboratory Medicine 3, no. 2 (September 1, 2018): 178–84. http://dx.doi.org/10.1373/jalm.2018.026278.
Full textAlmeida, Thiago Lins, Jessica Ribeiro Gomes, Marcel Cerqueira Cesar Machado, Antonio C. Buzaid, and Fernando C. Maluf. "RAS mutations and their correlation with survival of patients with advanced pancreatic adenocarcinoma." Journal of Clinical Oncology 33, no. 3_suppl (January 20, 2015): 325. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.325.
Full textWen, Zhengqi, Hushan Zhang, Ruize Zhou, Xihong Liu, and Wenliang Li. "Abstract 5403: Genetic, immunologic and prognostic heterogeneity in CRC patients with KRAS mutations." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5403. http://dx.doi.org/10.1158/1538-7445.am2022-5403.
Full textKobayashi, T., T. Masaki, H. Matsuoka, and M. Sugiyama. "Anti-EGFR Antibody Treatment in KRAS G13D Mutation-Type Colorectal Cancers: Case Reports." Annals of Oncology 23 (October 2012): xi159. http://dx.doi.org/10.1016/s0923-7534(20)32500-x.
Full textEl zaitouni, Sara, Abdelilah Laraqui, Meriem Ghaouti, Asmae Benzekri, Fouad Kettani, Hicham El Annaz, Rachid Abi, et al. "Mutation status of full RAS and BRAF in 169 Moroccan patients with colorectal cancer." Journal of Clinical Oncology 41, no. 4_suppl (February 1, 2023): 216. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.216.
Full textNi Nyoman, Ayu Dewi, Ni Made Pramita Widya Suksmarini, Anak Agung Ngurah Satya Pranata, Andreliano Yosua Rompis, and I. Wayan Juli Sumadi. "The prevalence of KRAS and BRAF mutation in colorectal cancer patients in Bali." Indonesian Journal of Biotechnology 27, no. 1 (March 29, 2022): 29. http://dx.doi.org/10.22146/ijbiotech.67506.
Full textNing, Wenjuan, Zhang Yang, Gregor J. Kocher, Patrick Dorn, and Ren-Wang Peng. "A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished." Cancers 14, no. 2 (January 13, 2022): 390. http://dx.doi.org/10.3390/cancers14020390.
Full textLu, Lianghao, Julie Niemela, Thomas Fleisher, Joie Davis, Iusta Caminha, Mark Natter, Laurel Beer, et al. "Somatic KRAS mutations associated with a human non-malignant syndrome of autoimmunity and abnormal leukocyte homeostasis (47.4)." Journal of Immunology 186, no. 1_Supplement (April 1, 2011): 47.4. http://dx.doi.org/10.4049/jimmunol.186.supp.47.4.
Full textYu, Helena Alexandra, Camelia S. Sima, Ronglai Shen, Samantha Lindsay Kass, Mark G. Kris, Marc Ladanyi, and Gregory J. Riely. "Comparison of the characteristics and clinical course of 677 patients with metastatic lung cancers with mutations in KRAS codons 12 and 13." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 8025. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.8025.
Full textLiu, Li, Yuan Liu, Ademi Santiago-Walker, Hong Shi, Vivian Zhang, Ashley Hughes, Carmen P. Arenas-Elliott, Lori Roadcap, Anne-Marie Martin, and Tona M. Gilmer. "Genetic and molecular biomarker characterization of KRAS mutant non-small cell lung carcinoma (NSCLC) tumors." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 11026. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.11026.
Full textMuthiah, Arun, Rani Chudasama, Adam J. Olszewski, Harish Saiganesh, Habibe Kurt, Jennifer Mingrino, Maria Garcia-Moliner, et al. "Clinical characteristics, co-mutations and outcomes of advanced non-small cell lung cancer (NSCLC) patients with KRAS mutations." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e21174-e21174. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e21174.
Full textStover, D. G., A. M. Cushman-Vokoun, C. L. Vnencak-Jones, and J. Berlin. "Analysis of BRAF and KRAS mutations in colorectal cancer and rectal carcinogenesis via fluorescent allele-specific PCR." Journal of Clinical Oncology 29, no. 4_suppl (February 1, 2011): 436. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.436.
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