Journal articles on the topic 'G-protein'

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1

Iyengar, R. "Structure of G Protein-Coupled Receptors and G Proteins." Science Signaling 2005, no. 276 (March 18, 2005): tr10. http://dx.doi.org/10.1126/stke.2762005tr10.

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2

Andreeva, Alexandra V., Mikhail A. Kutuzov, and Tatyana A. Voyno- Yasenetskaya. "Scaffolding proteins in G-protein signaling." Journal of Molecular Signaling 2 (October 30, 2007): 13. http://dx.doi.org/10.1186/1750-2187-2-13.

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3

Santagata, S. "G-Protein Signaling Through Tubby Proteins." Science 292, no. 5524 (May 24, 2001): 2041–50. http://dx.doi.org/10.1126/science.1061233.

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4

Spiegel, Allen M., and Lee S. Weinstein. "Inherited Diseases Involving G Proteins and G Protein–Coupled Receptors." Annual Review of Medicine 55, no. 1 (February 2004): 27–39. http://dx.doi.org/10.1146/annurev.med.55.091902.103843.

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5

Campbell, Adrian P., and Alan V. Smrcka. "Targeting G protein-coupled receptor signalling by blocking G proteins." Nature Reviews Drug Discovery 17, no. 11 (September 28, 2018): 789–803. http://dx.doi.org/10.1038/nrd.2018.135.

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6

Morikawa, T., T. Ishii, A. Arai, T. Kohno, K. Sato, Y. Kato, M. Tanokura, and K. Wakamatsu. "Interaction of G protein with G protein activating peptides." Seibutsu Butsuri 43, supplement (2003): S181. http://dx.doi.org/10.2142/biophys.43.s181_1.

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7

Oldham, William M., and Heidi E. Hamm. "Heterotrimeric G protein activation by G-protein-coupled receptors." Nature Reviews Molecular Cell Biology 9, no. 1 (January 2008): 60–71. http://dx.doi.org/10.1038/nrm2299.

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8

Heuss, Christian, and Urs Gerber. "G-protein-independent signaling by G-protein-coupled receptors." Trends in Neurosciences 23, no. 10 (October 2000): 469–75. http://dx.doi.org/10.1016/s0166-2236(00)01643-x.

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9

Blumer, Joe B., and Stephen M. Lanier. "Accessory Proteins for G Protein-Signaling Systems: Activators of G Protein Signaling and Other Nonreceptor Proteins Influencing the Activation State of G Proteins." Receptors and Channels 9, no. 3 (January 2003): 195–204. http://dx.doi.org/10.3109/10606820308240.

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10

Blumer, Joe B., and Stephen M. Lanier. "Accessory Proteins for G Protein-Signaling Systems: Activators of G Protein Signaling and Other Nonreceptor Proteins Influencing the Activation State of G Proteins." Receptors and Channels 9, no. 3 (May 1, 2003): 195–204. http://dx.doi.org/10.1080/10606820308240.

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11

Blumer, J. B., S. S. Oner, and S. M. Lanier. "Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif." Acta Physiologica 204, no. 2 (July 5, 2011): 202–18. http://dx.doi.org/10.1111/j.1748-1716.2011.02327.x.

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12

Kimple, Randall, Miller Jones, Adam Shutes, Benjamin Yerxa, David Siderovski, and Francis Willard. "Established and Emerging Fluorescence-Based Assays for G-Protein Function: Heterotrimeric G-Protein Alpha Subunits and Regulator of G-Protein Signaling (RGS) Proteins." Combinatorial Chemistry & High Throughput Screening 6, no. 4 (June 1, 2003): 399–407. http://dx.doi.org/10.2174/138620703106298491.

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13

Neves, S. R. "G Protein Pathways." Science 296, no. 5573 (May 31, 2002): 1636–39. http://dx.doi.org/10.1126/science.1071550.

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14

Diverse-Pierluissi, M. "G Protein Effectors." Science Signaling 2005, no. 281 (April 19, 2005): tr13. http://dx.doi.org/10.1126/stke.2812005tr13.

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15

Ray, L. B. "Integrin G Protein." Science Signaling 3, no. 105 (January 19, 2010): ec19-ec19. http://dx.doi.org/10.1126/scisignal.3105ec19.

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16

Foley, J. F. "Adaptable G Protein." Science Signaling 3, no. 120 (May 4, 2010): ec131-ec131. http://dx.doi.org/10.1126/scisignal.3120ec131.

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17

Albert, Paul R., and Liliane Robillard. "G protein specificity." Cellular Signalling 14, no. 5 (May 2002): 407–18. http://dx.doi.org/10.1016/s0898-6568(01)00259-5.

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18

Freissmuth, Michael, Maria Waldhoer, Elisa Bofill-Cardona, and Christian Nanoff. "G protein antagonists." Trends in Pharmacological Sciences 20, no. 6 (June 1999): 237–45. http://dx.doi.org/10.1016/s0165-6147(99)01337-1.

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19

Wu, Yan Yun, Sandro Sonnino, Yu-Teh Li, and Su-Chen Li. "Characterization of an Alternatively Spliced G Activator Protein, G Protein." Journal of Biological Chemistry 271, no. 18 (May 3, 1996): 10611–15. http://dx.doi.org/10.1074/jbc.271.18.10611.

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20

Hu, Jianxin, Yan Wang, Xiaohong Zhang, John R. Lloyd, Jian Hua Li, Joel Karpiak, Stefano Costanzi, and Jürgen Wess. "Structural basis of G protein–coupled receptor–G protein interactions." Nature Chemical Biology 6, no. 7 (May 30, 2010): 541–48. http://dx.doi.org/10.1038/nchembio.385.

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21

Slusarz, Rafał, and Jerzy Ciarkowski. "Interaction of class A G protein-coupled receptors with G proteins." Acta Biochimica Polonica 51, no. 1 (March 31, 2004): 129–36. http://dx.doi.org/10.18388/abp.2004_3604.

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A model for interaction of class A G protein-coupled receptor with the G protein G(alpha) subunit is proposed using the rhodopsin-transducin (RD/Gt) prototype. The model combines the resolved interactions/distances, essential in the active RD*/Gt system, with the structure of Gt(alpha) C-terminal peptide bound to RD* while stabilizing it. Assuming the interactions involve conserved parts of the partners, the model specifies the conserved Helix 2 non-polar X- - -X, Helix 3 DRY and Helix 7/8 NP- -Y- - F RD* motifs interacting with the Gt(alpha) C-terminal peptide, in compliance with the structure of the latter. A concomitant role of Gt(alpha) and Gt(gamma) C-termini in stabilizing RD* could possibly be resolved assuming a receptor dimer as requisite for G protein activation.
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22

Dhanasekaran, N., and J. Silvio Gutkind. "Signaling by G protein coupled receptors and G proteins: a perspective." Oncogene 20, no. 13 (March 2001): 1530–31. http://dx.doi.org/10.1038/sj.onc.1204273.

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23

Assmann, S. M. "G Proteins Go Green: A Plant G Protein Signaling FAQ Sheet." Science 310, no. 5745 (October 7, 2005): 71–73. http://dx.doi.org/10.1126/science.1118580.

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24

Marucci, Gabriella, Francesca Novi, Rita Banzi, Maria L. Bolognesi, Michela Buccioni, Anna Minarini, Michela Rosini, Piero Angeli, Roberto Maggio, and Carlo Melchiorre. "Polyamines May Modulate Both G Protein-Coupled Receptors and G Proteins." Medicinal Chemistry Research 13, no. 1-2 (January 2004): 63–73. http://dx.doi.org/10.1007/s00044-004-0010-1.

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25

Bockaert, Jöel. "G proteins and G-protein-coupled receptors: structure, function and interactions." Current Opinion in Neurobiology 1, no. 1 (June 1991): 32–42. http://dx.doi.org/10.1016/0959-4388(91)90008-u.

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26

Arang, Nadia, and J. Silvio Gutkind. "G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers." FEBS Letters 594, no. 24 (December 2020): 4201–32. http://dx.doi.org/10.1002/1873-3468.14017.

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27

Sun, Shuhua, and Andrew M. Lew. "Chimaeric protein A/protein G and protein G/alkaline phosphatase as reporter molecules." Journal of Immunological Methods 152, no. 1 (July 1992): 43–48. http://dx.doi.org/10.1016/0022-1759(92)90087-a.

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28

Roy Choudhury, Swarup, Corey S. Westfall, John P. Laborde, Naveen C. Bisht, Joseph M. Jez, and Sona Pandey. "Two Chimeric Regulators of G-protein Signaling (RGS) Proteins Differentially Modulate Soybean Heterotrimeric G-protein Cycle." Journal of Biological Chemistry 287, no. 21 (April 2, 2012): 17870–81. http://dx.doi.org/10.1074/jbc.m112.353219.

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29

Suga, Hinako, and Tatsuya Haga. "Ligand screening system using fusion proteins of G protein-coupled receptors with G protein α subunits." Neurochemistry International 51, no. 2-4 (July 2007): 140–64. http://dx.doi.org/10.1016/j.neuint.2007.06.006.

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30

Gsandtner, Ingrid, Christoforos Charalambous, Eduard Stefan, Egon Ogris, Michael Freissmuth, and Jürgen Zezula. "Heterotrimeric G Protein-independent Signaling of a G Protein-coupled Receptor." Journal of Biological Chemistry 280, no. 36 (July 18, 2005): 31898–905. http://dx.doi.org/10.1074/jbc.m506515200.

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31

Sulon, Sarah M., and Jeffrey L. Benovic. "Targeting G protein–coupled receptor kinases to G protein–coupled receptors." Current Opinion in Endocrine and Metabolic Research 16 (February 2021): 56–65. http://dx.doi.org/10.1016/j.coemr.2020.09.002.

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32

Duc, Nguyen Minh, Hee Ryung Kim, and Ka Young Chung. "Structural mechanism of G protein activation by G protein-coupled receptor." European Journal of Pharmacology 763 (September 2015): 214–22. http://dx.doi.org/10.1016/j.ejphar.2015.05.016.

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33

Bünemann, Moritz, and M. Marlene Hosey. "G-protein coupled receptor kinases as modulators of G-protein signalling." Journal of Physiology 517, no. 1 (May 1999): 5–23. http://dx.doi.org/10.1111/j.1469-7793.1999.0005z.x.

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34

Escribá, Pablo V., Jesús Casas, Rafael Álvarez, Victoria Lladó, and Silvia Terés. "Effect of G protein lipid modifications on G protein membrane interactions." Chemistry and Physics of Lipids 149 (September 2007): S26. http://dx.doi.org/10.1016/j.chemphyslip.2007.06.055.

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35

MILLIGAN, G., G. PARENTY, L. STODDART, and J. LANE. "Novel pharmacological applications of G-protein-coupled receptor–G protein fusions." Current Opinion in Pharmacology 7, no. 5 (October 2007): 521–26. http://dx.doi.org/10.1016/j.coph.2007.06.007.

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36

Milligan, Graeme, and Julia H. White. "Protein–protein interactions at G-protein-coupled receptors." Trends in Pharmacological Sciences 22, no. 10 (October 2001): 513–18. http://dx.doi.org/10.1016/s0165-6147(00)01801-0.

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37

Gu, Jennifer L., Wei Lu, Chunzhi Xia, Xiushan Wu, and Mingyao Liu. "Regulation of hematopoietic-specific G-protein G?15 and G?16 by protein kinase C." Journal of Cellular Biochemistry 88, no. 6 (March 10, 2003): 1101–11. http://dx.doi.org/10.1002/jcb.10455.

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38

Brass, Lawrence F., James A. Hoxie, and David R. Manning. "Signaling through G Proteins and G Protein-coupled Receptors during Platelet Activation." Thrombosis and Haemostasis 70, no. 01 (1993): 217–23. http://dx.doi.org/10.1055/s-0038-1646194.

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SummaryRecent studies have helped to define the early events of signal transduction in platelets. The best-described of these events are those in which heterotrimeric guanine nucleotide binding regulatory proteins (G proteins) mediate the interaction between cell surface receptors for agonists and intracellular second messenger generating enzymes. To date nine different G proteins have been identified in platelets. The:r targets include phospholipases C and A2, and adenylyl cyclase. Efforts to clone the receptors that can couple to these G proteins have been successful for epinephrine, thrombin, TxA2 and platelet activating factor. Each of these is comprised of a single polypeptide with seven transmembrane domains and an extracellular N-terminus. In the case of the thrombin receptor, activation occurs by a novel mechanism in which thrombin cleaves its receptor, creating a new N-terminus that can serve as a tethered ligand. Shortly after activation, thrombin receptors become resistant to re-activation by thrombin. This desensitization, which appears to involve receptor phosphorylation and internalization, provides a potent mechanism for limiting the duration of thrombin-initiated events in platelets and other thrombin-responsive vascular cells.
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39

Spiegel, A. M. "Mutations in G proteins and G protein-coupled receptors in endocrine disease." Journal of Clinical Endocrinology & Metabolism 81, no. 7 (July 1, 1996): 2434–42. http://dx.doi.org/10.1210/jc.81.7.2434.

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40

Cordomí, Arnau, Gemma Navarro, María S. Aymerich, and Rafael Franco. "Structures for G-Protein-Coupled Receptor Tetramers in Complex with G Proteins." Trends in Biochemical Sciences 40, no. 10 (October 2015): 548–51. http://dx.doi.org/10.1016/j.tibs.2015.07.007.

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41

Spiegel, A. M. "Mutations in G proteins and G protein-coupled receptors in endocrine disease." Journal of Clinical Endocrinology & Metabolism 81, no. 7 (July 1996): 2434–42. http://dx.doi.org/10.1210/jcem.81.7.8675557.

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42

Nobles, M., A. Benians, and A. Tinker. "Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells." Proceedings of the National Academy of Sciences 102, no. 51 (December 13, 2005): 18706–11. http://dx.doi.org/10.1073/pnas.0504778102.

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43

Tsvetanova, Nikoleta G., Roshanak Irannejad, and Mark von Zastrow. "G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes." Journal of Biological Chemistry 290, no. 11 (January 20, 2015): 6689–96. http://dx.doi.org/10.1074/jbc.r114.617951.

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44

Casas, Jesús, Maitane Ibarguren, Rafael Álvarez, Silvia Terés, Victoria Lladó, Stefano P. Piotto, Simona Concilio, Xavier Busquets, David J. López, and Pablo V. Escribá. "G protein-membrane interactions II: Effect of G protein-linked lipids on membrane structure and G protein-membrane interactions." Biochimica et Biophysica Acta (BBA) - Biomembranes 1859, no. 9 (September 2017): 1526–35. http://dx.doi.org/10.1016/j.bbamem.2017.04.005.

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45

Claing, A. "Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and ß-arrestin proteins." Progress in Neurobiology 66, no. 2 (February 2002): 61–79. http://dx.doi.org/10.1016/s0301-0082(01)00023-5.

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46

Mark, Melanie D., Silke Wittemann, and Stefan Herlitze. "G protein modulation of recombinant P/Q‐type calcium channels by regulators of G protein signalling proteins." Journal of Physiology 528, no. 1 (October 2000): 65–77. http://dx.doi.org/10.1111/j.1469-7793.2000.00065.x.

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47

Ross, Elliott M. "G Protein-coupled receptors." Cellular Logistics 4, no. 2 (May 2014): e29391. http://dx.doi.org/10.4161/cl.29391.

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48

Depraetere, Valerie. "G-protein activation live." Nature Cell Biology 3, no. 5 (May 2001): E107. http://dx.doi.org/10.1038/35074622.

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49

Clapham, David E. "The G-protein nanomachine." Nature 379, no. 6563 (January 1996): 297–99. http://dx.doi.org/10.1038/379297a0.

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50

Challiss, R. A. John, and Jürgen Wess. "GPCR–G protein preassembly?" Nature Chemical Biology 7, no. 10 (September 19, 2011): 657–58. http://dx.doi.org/10.1038/nchembio.665.

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