Dissertations / Theses on the topic 'Fusion musculaire'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 16 dissertations / theses for your research on the topic 'Fusion musculaire.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
BLENEAU, SEVERINE. "Etude par rmn bi-dimensionnelle de la fusion des myoblastes et de la regeneration musculaire." Paris 6, 1999. http://www.theses.fr/1999PA066063.
Full textLý, Hà My. "Characterization of a novel molecular pathway linking metabolic regulation and muscle stem cell fate." Electronic Thesis or Diss., Lyon 1, 2024. http://www.theses.fr/2024LYO10193.
Full textMuscle stem cells (MuSCs) provide a constant regenerative capacity to the skeletal muscle owing to their capacity to recapitulate a myogenic program upon muscle lesion. Alterations of MuSC myogenic capacity are associated to muscle loss with age, but also debilitating diseases such as myopathies. Metabolic plasticity is a hallmark of MuSC fate program. Based on previous work from the lab highlighting a central role for the metabolic regulator kinase AMPK in adult myogenesis, I adopted a candidate-based study that identified NUAK1, an AMPK-related kinase whose function is associated to metabolic regulation in developing neurons, as a novel player in the regulation of MuSC fate and adult myogenesis. NUAK1 expression is required for muscle regeneration capacity and NUAK1 controls sequential aspects of the myogenic program, ie. MuSC commitment and differentiation into myoblast, myoblast fusion to produce mature myofibers, and MuSC renewal. On a molecular level, I obtained exciting preliminary data suggesting that NUAK1 acts through the regulation of fatty acids and cholesterol biogenesis. During my PhD, I confirm this link and decipher how the transcription factor SREBP1, which controls lipid metabolic pathways, mediates the functions of NUAK1 during adult myogenesis. This candidate-based study completes by an unbiased approach aiming at identifying changes in mitochondrial metabolism. Overall, my PhD work demonstrate an original link between lipids metabolism and MuSC fate, which will give hints toward putative targets of therapeutic value
Girardi, Francesco. "TGFbeta signalling pathway in muscle regeneration : an important regulator of muscle cell fusion." Electronic Thesis or Diss., Sorbonne université, 2019. http://www.theses.fr/2019SORUS114.
Full textMuscle regeneration relies on a pool of muscle-resident stem cells called satellite cells (MuSCs). MuSCs are quiescent and can activate following muscle injury to give rise to transient amplifying progenitors (myoblasts) that will differentiate and finally fuse together to form new myofibers. During this process, a complex network of signalling pathways is involved, among which, Transforming Growth Factor beta (TGFβ) signalling cascade plays a fundamental role. Previous reports proposed several functions for TGFβ signalling in muscle cells including quiescence, activation and differentiation. However, the impact of TGFβ on myoblast fusion has never been investigated. In this study, we show that TGFβ signalling reduces muscle cell fusion independently of the differentiation step. In contrast, inhibition of TGFβ signalling enhances cell fusion and promotes branching between myotubes. Pharmacological modulation of the pathway in vivo perturbs muscle regeneration after injury. Exogenous addition of TGFβ protein results in a loss of muscle function while inhibition of the TGFβ pathway induces the formation of giant myofibres. Transcriptome analyses and functional assays revealed that TGFβ acts on actin dynamics to reduce cell spreading through modulation of actin-based protrusions. Together our results reveal a signalling pathway that limits mammalian myoblast fusion and add a new level of understanding to the molecular regulation of myogenesis
De, la celle Marie. "Etude de deux aspects de la myogenèse chez l'embryon de poulet : la transition epitheliomesenchymateuse et la fusion des myoblastes." Aix-Marseille 2, 2009. http://theses.univ-amu.fr.lama.univ-amu.fr/2009AIX22077.pdf.
Full textIn vertebrates, sketetal muscles of the trunk and the limbs form in two stages, from the dermomyotome (DM) : 1) cells located at the four borders of the DM delaminate to generate the primary myotome (PM); 2) cells from the central part of the DM undergo an epitheliomesenchymal transition (EMT), characterrised by a massive entrey of muscle progenitors into the PM. A myoblast fusion process allows the myotome growth. I analysed the temporal regulation of the EMT initiation. We propose that this process is regulated by a FGF signal emanating from the PM, that riggers within the DM a MAPK/ERK pathway that leads to the activation of the transcription factor Snail 1, a regulator of EMT. Then, I showed that the fuion process is initiated between mononucleated myocytes and muscles progenitors, 36h after somite formation. The loss of function of Tanc1, Arf6 and NCKAP1 genes, orthologous of Rols1, Arf6 and Kette genes of drosophila, suggests that theses genes regulate the fusion process
Wu, Melissa P. "Enhancing Myoblast Fusion for Therapy of Muscular Dystrophies." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10740.
Full textLafuste, Peggy Authier François-Jérôme. "Mécanismes moléculaires impliqués dans la fusion des cellules précurseurs myogéniques humains." Créteil : Université de Paris-Val-de-Marne, 2004. http://doxa.scd.univ-paris12.fr:80/theses/th0214091.pdf.
Full textFongy, Anais. "Implication potentielle des protéines de fusion mitochondriale dans l'ontogenèse des processus bioénergétiques musculaires chez l'oiseau." Thesis, Lyon 1, 2013. http://www.theses.fr/2013LYO10276/document.
Full textCold-exposed young birds maintain their homeothermy by stimulating mitochondrial oxidations in skeletal muscle. Prolonged cold exposure enhances muscle thermogenic capacities through mitochondrial bioenergetics plasticity which control still remains hypothetical. In mammals, fusion proteins (mitofusins (Mfns) and OPA1 (Optic Atrophy 1)) contribute to the permanent and dynamic changes in mitochondrial networks in multiple cell types. The aim of our work was to characterize the expression of avian homologues of mammalian fusion proteins and to study the variations of their expression during the establishment of bioenergetics processes in growing birds, during an acute or a prolonged cold exposure and finally during nutritional or endocrine challenges. Methodologically, an integrative approach has been used from whole animal (indirect calorimetry) to protein (western-blot) or gene (RT-PCR) expression through measurements of the bioenergetics functionality of permeabilized muscle fibers and isolated mitochondria. Two animal models were used, a species naturally adapted to Antarctica harsh conditions, the Adélie penguin (Pygoscelis adeliae), and a laboratory model, the Muscovy duck (Cairina moschata).Our results allowed us to characterize, in birds, the expression of immunoreactive fusion proteins (Mfn2, OPA1) which were homologous to those of mammals. The sequencing of a part of the coding sequence of Mfns genes showed a great similitude between avian and mammalian species. In penguins, the relative abundance of these proteins in muscle mitochondria was modified by growth in the cold and was positively correlated with muscle bioenergetics capacities. In ducks, the respiratory activity and the relative abundance of these proteins were also correlated after a 60h fasting period or,though a lesser extent, after a pharmacological alteration of thyroid status. Our results show, for the first time in birds, the expression of proteins homologous to mammalian fusion proteins. The association between the changes in expression of these proteins and the bioenergetics modifications in skeletal muscle indicates that these proteins could contribute to thebioenergetics plasticity observed in growing chicks. These results suggest that potential modifications of the muscle mitochondrial network organization could play a role in the adaptive responses of organisms to the environmental constraints
Félix, de Melo Juliana. "Molécules de fusion et facteurs de transcription dans les macrophages et cellules musculaires squelettiques de rats : l'effet de la dénutrition néonatale." Compiègne, 2012. http://www.theses.fr/2012COMP2000.
Full textIn this thesis, we evaluated the late effects of neonatal undernutrition on the expression/production of fusion molecules and transcriptional factors in alveolar macrophages and skeletal muscle cells. Thirty-six male Wistar rats were suckled by mothers fed diets containing 17% casein, control group (C) or 8% casein, undernourished group (UN) during lactation. After weaning, all animals received a normoproteic diet (Labina or Teklad Global), at 42 days (n=12), 60 days (n=12) and 90 days (n=12). Half of these animals (n=18) were submitted to a tracheostomy for the removal of bronchoalveolar lavage and subsequent culture of alveolar macrophages for 4 days. In the other half (n = 18), all muscles of both legs were removed and the skeletal muscle cells cultured for 10 days. This resulted in two original articles. The first of these, entitled “Long-term effects of a neonatal low-protein diet in rats on the number of macrophages in culture and the expression/production of fusion proteins”, allowed us to observe that undernutrition during lactation altered the number of macrophages in culture and the production of fusion proteins in young and adult rats, but did not modify the expression of cadherin adhesion molecules. The second article, entitled “Effect of a neonatal low-protein diet on the morphology of myotubes in culture and the expression of key proteins that regulate myogenesis in young and adult rats”, demonstrated that neonatal undernutrition did not modify the expression of key proteins of the myogenic process but altered the morphology and reduced the number of myotubes in culture from 60-day-old rats. In conclusion, neonatal undernutrition caused sequelae in young and adult organisms, even after nutritional recovery. These changes were evidenced in the development of alveolar macrophages in culture and myogenesis
Petrany, Michael J. "Consequences of Cell Fusion and Multinucleation for Skeletal Muscle Development and Disease." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595847866440328.
Full textJacquemin, Virginie. "Mécanismes cellulaires et moléculaires impliqués dans l'hypertrophie des myotubes humains induite par l'IGF-1." Paris 7, 2006. http://www.theses.fr/2006PA077195.
Full textIGF-1 (Insulin-like Growth factor 1) is a growth factor secreted by the liver in response to GH, but also expressed locally in muscle where it plays a key role in the control of muscle mass. Overexpressed in the muscle of mice, IGF-1 induces muscle hypertrophy and prevents the loss of muscle mass that occurs with aging. In the present study, the ability of IGF-1 to induce myotube hypertrophy has been confirmed in a model of primary human myoblasts. By treating cultures with IGF-1 after 3 days of differentiation, we developed a model of human myotube hypertrophy independent of cell proliferation and charaterized by an increase in fusion index, resulting from the increased recruitment of reserve cells for differentiation and fusion. Using this model, we show that IGF-1 exclusively signals on myotubes but not on reserve cells, suggesting the existence of a secondary mechanism triggered by the myotubes inducing reserve cell recruitment for fusion. Using conditioned medium we observed that a soluble factor secreted by myotubes is responsible for this increase in reserve cell recruitment for fusion in response to IGF-1. This factor was identified as Interleukin-13 using a neutralizing antibody and exogenous treatment. We demonstrate that the expression of IL-13 is induced via the transcription factor NFATcl in response to IGF-1, and is responsible for the increased recruitment of reserve cells for fusion during human myotube hypertrophy induced by IGF-1
Félix, de Melo Juliana. "Moléculas de fusão e fatores transcricionais em macrófagos e células musculares esqueléticas de ratos: efeito da desnutrição neonatal." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/7403.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
Nesta tese avaliamos os efeitos tardios da desnutrição neonatal sobre a expressão/produção de moléculas de fusão e fatores transcricionais em macrófagos alveolares e células musculares esqueléticas. Foram utilizados 36 ratos, machos, Wistar, amamentados por mães que receberam dieta durante a lactação contendo 17% de caseína, grupo nutrido (N) ou 8% de caseína, grupo desnutrido (D). Após o desmame, os animais foram recuperados com dieta Labina ou Teklad Global, até 42 dias (n=12), 60 dias (n=12) e 90 dias de vida (n=12). Metade destes animais (n=18) foi submetida a um procedimento cirúrgico de traqueostomia objetivando a retirada de lavado broncoalveolar e posterior cultura dos macrófagos alveolares por 4 dias. Da outra metade (n=18), foram retirados todos os músculos de ambas as patas dos animais e realizada a cultura das células musculares esqueléticas durante 10 dias. Deste modo, os resultados geraram dois artigos originais. O primeiro intitulado Long-term effects of a neonatal low-protein diet in rats on the number of macrophages in culture and the expression/production of fusion proteins permitiu observar que a desnutrição durante a lactação alterou o número de macrófagos em cultura e a produção de proteínas de fusão em ratos jovens e adultos, mas não modificou a expressão das moléculas de adesão caderinas. O segundo intitulado Effect of a neonatal low-protein diet on the morphology of myotubes in culture and the expression of key proteins that regulate myogenesis in young and adult rats demonstrou que a desnutrição neonatal não modificou a expressão de proteínas-chaves do processo miogênico, mas alterou a morfologia e reduziu o número dos miotubos em cultura de animais com 60 dias de vida. Em conclusão, a desnutrição neonatal causou sequelas no organismo jovem e adulto, mesmo após a reposição nutricional. Estas alterações foram evidenciadas no desenvolvimento de macrófagos alveolares em cultura e na miogênese
Melo, Juliana Félix de. "Moléculas de fusão e fatores transcricionais em macrófagos e células musculares esqueléticas de ratos: efeito da desnutrição neonatal." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/11062.
Full textMade available in DSpace on 2015-03-06T13:09:06Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) TESE JULIANA FÉLIX DE MELO.pdf: 5715613 bytes, checksum: 73dc004deccea4e95d52c6dcf926c1f1 (MD5) Previous issue date: 2012-02-27
CAPES, CAPESCOFECUB
Nesta tese avaliamos os efeitos tardios da desnutrição neonatal sobre a expressão/produção de moléculas de fusão e fatores transcricionais em macrófagos alveolares e células musculares esqueléticas. Foram utilizados 36 ratos, machos, Wistar, amamentados por mães que receberam dieta durante a lactação contendo 17% de caseína, grupo nutrido (N) ou 8% de caseína, grupo desnutrido (D). Após o desmame, os animais foram recuperados com dieta Labina ou Teklad Global, até 42 dias (n=12), 60 dias (n=12) e 90 dias de vida (n=12). Metade destes animais (n=18) foi submetida a um procedimento cirúrgico de traqueostomia objetivando a retirada de lavado broncoalveolar e posterior cultura dos macrófagos alveolares por 4 dias. Da outra metade (n=18), foram retirados todos os músculos de ambas as patas dos animais e realizada a cultura das células musculares esqueléticas durante 10 dias. Deste modo, os resultados geraram dois artigos originais. O primeiro intitulado “Long-term effects of a neonatal low-protein diet in rats on the number of macrophages in culture and the expression/production of fusion proteins” permitiu observar que a desnutrição durante a lactação alterou o número de macrófagos em cultura e a produção de proteínas de fusão em ratos jovens e adultos, mas não modificou a expressão das moléculas de adesão caderinas. O segundo intitulado “Effect of a neonatal low-protein diet on the morphology of myotubes in culture and the expression of key proteins that regulate myogenesis in young and adult rats” demonstrou que a desnutrição neonatal não modificou a expressão de proteínas-chaves do processo miogênico, mas alterou a morfologia e reduziu o número dos miotubos em cultura de animais com 60 dias de vida. Em conclusão, a desnutrição neonatal causou sequelas no organismo jovem e adulto, mesmo após a reposição nutricional. Estas alterações foram evidenciadas no desenvolvimento de macrófagos alveolares em cultura e na miogênese.
SEIGNEURIN-VENIN, SOPHIE. "Etude de la differenciation myogenique in vitro : role de la sous-unite alpha 1 du canal ca#2#+ lent dans la fusion et la maturation des cellules musculaires squelettiques." Paris 6, 1996. http://www.theses.fr/1996PA066386.
Full textCastillo, Andrea Amaral. "Tônus muscular = uma contribuição para os estudos em imagem corporal." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/275086.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Educação Física
Made available in DSpace on 2018-08-18T10:27:09Z (GMT). No. of bitstreams: 1 Castillo_AndreaAmaral_M.pdf: 1424495 bytes, checksum: 2e616dc1accf2266891ba1011fc14c1e (MD5) Previous issue date: 2011
Resumo: A Imagem Corporal foi conceituada por Paul Schilder (1999) como a representação mental do corpo. Neste conceito ele aponta para uma abordagem sistêmica dos aspectos fisiológicos, psíquicos, sociais e culturais no processo dinâmico da expressão singular da identidade corporal. Em seu livro "The Image and appearance of humam body", publicado em 1935, Schilder chama a atenção para a relação entre o Tônus Muscular e a Imagem Corporal num capítulo exclusivo sobre o tema. Ressaltou que a Imagem Corporal era tracionada em direção ao Tônus Muscular uma vez que a ação de um único segmento corporal é capaz de colocar o corpo como um todo em uma nova relação com o ambiente. No entanto esta relação não se encontra sistematizada e valorizada dentro das diversas áreas do saber e tem sido pouco abordada nas pesquisas em Imagem Corporal. O foco direcionado ora ao Tônus Muscular, ora à Imagem Corporal implica muitas vezes num entendimento fragmentado capaz de desconsiderar a singularidade do indivíduo e/ou o dinamismo neurofisiológico na sua relação com o meio e com o outro. Assim a proposta deste estudo é sistematizar e analisar o conhecimento sobre o Tônus Muscular nas perspectivas de Charles Scott Sherrington cujo foco se apóia na Ação Reflexa; de Henry Head, que apresenta o Modelo Postural como a base para as pesquisas em Imagem Corporal; e da Neurociência, que propõe análises do comportamento humano na relação com o ambiente. Dentre as inúmeras contribuições feitas por Charles Scott Sherrington, foi a perspectiva da Ação Integrativa do sistema nervoso que trouxe um novo entendimento ao meio científico da época. Ao considerar a ação reflexa como uma resposta adaptativa do organismo, Sherrington encontrou no Tônus Muscular o exemplo explícito de um processo integrativo cuja proposta é manter a postura do organismo contra a gravidade. Henry Head influenciado por esse novo olhar, e inquieto com suas observações clínicas tornou-se o próprio objeto experimental numa investigação sobre os tipos de sensibilidade. A partir dos resultados de suas pesquisas e apoiado nas idéias e conceitos de Sherrington, Head propõe a existência de um Modelo Postural como uma medida de referência sobre a qual o corpo se ajusta constantemente através das variações do Tônus Muscular. Estas medidas são então registradas dentro de um esquema plástico de representação mental da postura e do movimento. A neurociência intensifica suas investigações sobre o organismo dentro do contexto do ambiente onde um é capaz de influenciar o outro. Com isso abriu-se uma nova perspectiva acerca do Tônus Muscular e o comportamento humano. As descobertas sobre a participação do fuso neuromuscular na elaboração da Imagem Corporal, as alterações mecânicas que implicam em alterações sensoriais e a ação segmentar que se propaga ao longo de todo o corpo trazem contribuições importantes que reforçam a relação íntima entre o Tônus Muscular e a representação mental do corpo. A partir deste estudo espera-se trazer uma reflexão mais profunda sobre o papel do Tônus Muscular e contribuir para futuras pesquisas e estudos sobre a Imagem Corporal
Abstract: Paul Schilder (1999) defined Body Image as the mental representation of the body. In this concept, he points out to a systemic approach of physiological, psychological, social and cultural aspects in the dynamic process of the body image unique expression. In his book "The Image and appearance of human body", published in 1935, Schilder draws attention to the relationship between Muscle Tonus and Body Image, dedicating a whole chapter to this theme. He emphasized that Body Image was pulled towards Muscle Tonus, since the action of a single body segment can place the whole body in a new interaction with the environment. However, this relationship has not been schematized and given the proper value by different areas of knowledge and it has been little addressed in studies about Body Image. Changing the focus from Muscle Tonus to Body Image back and forth can frequently lead to a fragmented understanding which may disregard each individual particularity and/or the neurophysiological dynamics in the individual interaction with the environment and others. Hence, this study aims to systematize and discuss the knowledge about muscle tone, as seen by Charles Scott Sherrington who focus on Reflex Action; by Henry Head, who presents Postural Model as fundamental for Body Image researches; and by Neuroscience, which suggests the study of human behavior and its relation with the environment. One of the several contributions by Charles Scott Sherrington, the Integrative Action of the nervous system brought a new understanding to the scientific community at the time. By considering reflex action as an adjustable response of the body, Sherrington saw the Muscle Tonus as a clear example of an integrative process which aims to keep the body posture against gravity. Henry Head was influenced by this new approach, and, out of a strong urge towards his clinical observation, became his own experiment subject on his study about sensitivity types. Supported by the results of his own researches and backed by Sherrington's concepts and ideas, Head suggests that there is a Postural Model acting as a reference measure which the body constantly fits into according to Muscle Tonus variations. These measures are registered within a scheme of posture and movement representations. Neuroscience stresses the focus of studies about the body within a context where one causes an impact on the other, bringing out a new outlook for Muscle Tone and human behavior. Findings about neuromuscular fuse participation in Body Image building, mechanical changes which cause sensorial changes and the segmental action which spreads throughout the body play an important role and corroborate the close relationship between Muscle Tonus and body mental representation. This study is expected to bring up a more comprehensive discussion on the role of Muscle Tonus and to enhance future researches and studies on Body Image
Mestrado
Atividade Fisica Adaptada
Mestre em Educação Física
Pedão, Sabrina Tiago. "Efeitos de diferentes freqüências e amplitudes de vibração unilateral do tendão calcâneo na orientação postural e no reflexo H em humanos." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/47/47135/tde-16042010-104819/.
Full textA vibration applied to a muscle tendon increases the firing frequency of afferents of types Ia and II innervating muscle spindles, and hence affects the spinal cord circuits and this can affect motor control. The aim of this study was to analyze the effect of vibrations of two frequencies (15 and 80Hz) and two amplitudes (1 and 2.5 mm) applied to the right Achilles tendon on the standing posture and on the H reflex. The hypothesis was that the high frequency vibration activates preferentially the Ia axons while the 15 Hz vibration activates preferentially the type II axons and hence the 80 Hz vibration would have a strong effect on the H reflex and the 15 Hz vibration would have a strong effect on posture. Fourteen subjects participated in this study. Their H reflex was acquired in the upright position while their Achilles tendon was vibrated. After an interval of rest, the center of pressure (COP) signal was acquired for both the antero-posterior (AP) and the medio-lateral (ML) directions in parallel with the acquisition of bilateral electromyograms (EMG) (SO, TA, and GL GM) in the three conditions (before, during and after the vibration of the Achilles tendon). For 1 and 2.5 mm vibrations at 80 Hz the differences were significant for all variables compared in the three conditions, except for the standard deviation (SD) of the TA and GM EMGs and the average value of COP ML for 1mm vibration. For the 15 Hz vibration, there were no significant differences in both the AP and ML COP and SD of the EMG of the left leg in the three conditions. The results for the EMG SD of the right leg showed no significant effects when using both 15Hz and 80Hz in all three conditions. These data showed that during a stronger vibratory stimulus the COP shifted more to the posterior direction and the left side of the subject. And, after stopping the stimulus, in some cases, the COP had not returned to the initial position. In relation to the mean H reflex amplitude for 1 and 2.5 mm vibrations at 15 and 80 Hz, the analysis showed that during vibration there was a stronger reduction in the amplitude of the H reflex, and in some cases the amplitude remained reduced in the post-vibratory period. The results showed that the vibration applied to the Achilles tendon can be a powerful stimulus to the spinal cord and capable of altering the postural control. The effects depended on the vibration features, since, with appropriate parameters, it led to immediate changes in the results of the H reflex, the COP and left leg EMG. However, 80 Hz vibration (1 and 2.5 mm) was the one that caused the largest changes both on COP and H reflex amplitude. The significant action on the H reflex is consistent with the increased frequency of firing of Ia afferent. However the strong action on the COP of vibrations at 80 Hz suggests that the Ia afferents may have a greater importance than what the recent literature has suggested, at least for postural corrections to disturbances, since it can be assumed that the type II afferents are little activated at 80 Hz and 1 mm amplitude. Furthermore, vibration at 15 Hz had a significant effect on the H reflex without affecting the COP, suggesting that vibrations at this frequency can activate Ia afferents, causing homosynaptic depression and / or presynaptic inhibition of Ia afferents, but without influencing the COP significantly. The results are interesting from the standpoint of potential applications to areas such as physical therapy and rehabilitation of patients in the clinic. Additionally, they raise new questions about the physiological mechanisms behind vibratory stimuli applied at different frequencies on the Achilles tendon.
Hecker, Marina Magdalena. "Langzeitergebnisse von operativ versorgten Wirbelsäulendeformitäten bei Kindern mit Spinaler Muskelatrophie." Doctoral thesis, 2020. http://hdl.handle.net/21.11130/00-1735-0000-0005-14E8-F.
Full text