Journal articles on the topic 'Furin site'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Furin site.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
Tian, Sun. "A 20 Residues Motif Delineates the Furin Cleavage Site and its Physical Properties May Influence Viral Fusion." Biochemistry Insights 2 (January 2009): BCI.S2049. http://dx.doi.org/10.4137/bci.s2049.
Full textYamada, Yoshiyuki, and Ding Xiang Liu. "Proteolytic Activation of the Spike Protein at a Novel RRRR/S Motif Is Implicated in Furin-Dependent Entry, Syncytium Formation, and Infectivity of Coronavirus Infectious Bronchitis Virus in Cultured Cells." Journal of Virology 83, no. 17 (June 24, 2009): 8744–58. http://dx.doi.org/10.1128/jvi.00613-09.
Full textCheng, Jinlong, Ye Zhao, Gang Xu, Keran Zhang, Wenfeng Jia, Yali Sun, Jing Zhao, Jia Xue, Yanxin Hu, and Guozhong Zhang. "The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism." Viruses 11, no. 10 (October 22, 2019): 972. http://dx.doi.org/10.3390/v11100972.
Full textSiner, Joshua I., Julie M. Crudele, Courtney T. Connolly, Shangzhen Zhou, Elizabeth P. Merricks, Timothy C. Nichols, Rodney M. Camire, and Valder R. Arruda. "Unexpected Role of PACE/Furin Cleavage Site in FVIII Biology: Implications for Hemophilia a Therapy." Blood 124, no. 21 (December 6, 2014): 105. http://dx.doi.org/10.1182/blood.v124.21.105.105.
Full textPapa, Guido, Donna L. Mallery, Anna Albecka, Lawrence G. Welch, Jérôme Cattin-Ortolá, Jakub Luptak, David Paul, et al. "Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion." PLOS Pathogens 17, no. 1 (January 25, 2021): e1009246. http://dx.doi.org/10.1371/journal.ppat.1009246.
Full textWanyiri, Jane W., Roberta O'Connor, Geneve Allison, Kami Kim, Anne Kane, Jiazhou Qiu, Andrew G. Plaut, and Honorine D. Ward. "Proteolytic Processing of the Cryptosporidium Glycoprotein gp40/15 by Human Furin and by a Parasite-Derived Furin-Like Protease Activity." Infection and Immunity 75, no. 1 (October 16, 2006): 184–92. http://dx.doi.org/10.1128/iai.00944-06.
Full textGeiselhart, Verena, Patrizia Bastone, Tore Kempf, Martina Schnölzer, and Martin Löchelt. "Furin-Mediated Cleavage of the Feline Foamy Virus Env Leader Protein." Journal of Virology 78, no. 24 (December 15, 2004): 13573–81. http://dx.doi.org/10.1128/jvi.78.24.13573-13581.2004.
Full textCui, Yanzhen, Renee Hackenmiller, Linnea Berg, François Jean, Takuya Nakayama, Gary Thomas, and Jan L. Christian. "The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor." Genes & Development 15, no. 21 (November 1, 2001): 2797–802. http://dx.doi.org/10.1101/gad.940001.
Full textGendron, Fernand-Pierre, Sébastien Mongrain, Patrick Laprise, Stéphanie McMahon, Claire M. Dubois, Mylène Blais, Claude Asselin, and Nathalie Rivard. "The CDX2 transcription factor regulates furin expression during intestinal epithelial cell differentiation." American Journal of Physiology-Gastrointestinal and Liver Physiology 290, no. 2 (February 2006): G310—G318. http://dx.doi.org/10.1152/ajpgi.00217.2005.
Full textMjokane, Nozethu, Maphori Maliehe, Olufemi S. Folorunso, Adepemi O. Ogundeji, Onele M. N. Gcilitshana, Jacobus Albertyn, Carolina H. Pohl, and Olihile M. Sebolai. "Cryptococcal Protease(s) and the Activation of SARS-CoV-2 Spike (S) Protein." Cells 11, no. 3 (January 27, 2022): 437. http://dx.doi.org/10.3390/cells11030437.
Full textThomas, Gary, Frédéric Couture, and Anna Kwiatkowska. "The Path to Therapeutic Furin Inhibitors: From Yeast Pheromones to SARS-CoV-2." International Journal of Molecular Sciences 23, no. 7 (March 22, 2022): 3435. http://dx.doi.org/10.3390/ijms23073435.
Full textGalanopoulou, A. S., N. G. Seidah, and Y. C. Patel. "Direct role of furin in mammalian prosomatostatin processing." Biochemical Journal 309, no. 1 (July 1, 1995): 33–40. http://dx.doi.org/10.1042/bj3090033.
Full textZhao, Ming, Lyn Gold, Ann M. Ginsberg, Li-Fang Liang, and Jurrien Dean. "Conserved Furin Cleavage Site Not Essential for Secretion and Integration of ZP3 into the Extracellular Egg Coat of Transgenic Mice." Molecular and Cellular Biology 22, no. 9 (May 1, 2002): 3111–20. http://dx.doi.org/10.1128/mcb.22.9.3111-3120.2002.
Full textPearce, Kenneth H., Laurie K. Overton, Robert T. Gampe, George B. Barrett, J. David Taylor, David D. McKee, Nino Campobasso, Robert T. Nolte, and Robert A. Reid. "BacMam production and crystal structure of nonglycosylated apo human furin at 1.89 Å resolution." Acta Crystallographica Section F Structural Biology Communications 75, no. 4 (March 13, 2019): 239–45. http://dx.doi.org/10.1107/s2053230x19001419.
Full textPassero, Christopher J., Gunhild M. Mueller, Michael M. Myerburg, Marcelo D. Carattino, Rebecca P. Hughey, and Thomas R. Kleyman. "TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage site." American Journal of Physiology-Renal Physiology 302, no. 1 (January 1, 2012): F1—F8. http://dx.doi.org/10.1152/ajprenal.00330.2011.
Full textHossain, Md Shahadat, Mahafujul Islam Quadery Tonmoy, Atqiya Fariha, Md Sajedul Islam, Arpita Singha Roy, Md Nur Islam, Kumkum Kar, Mohammad Rahanur Alam, and Md Mizanur Rahaman. "Prediction of the Effects of Variants and Differential Expression of Key Host Genes ACE2, TMPRSS2, and FURIN in SARS-CoV-2 Pathogenesis: An In Silico Approach." Bioinformatics and Biology Insights 15 (January 2021): 117793222110546. http://dx.doi.org/10.1177/11779322211054684.
Full textSemenov, Alexander G., Natalia N. Tamm, Karina R. Seferian, Alexander B. Postnikov, Natalia S. Karpova, Daria V. Serebryanaya, Ekaterina V. Koshkina, Mihail I. Krasnoselsky, and Alexey G. Katrukha. "Processing of Pro–B-Type Natriuretic Peptide: Furin and Corin as Candidate Convertases2." Clinical Chemistry 56, no. 7 (July 1, 2010): 1166–76. http://dx.doi.org/10.1373/clinchem.2010.143883.
Full textAshworth, J. L., V. Kelly, M. J. Rock, C. A. Shuttleworth, and C. M. Kielty. "Regulation of fibrillin carboxy-terminal furin processing by N-glycosylation, and association of amino- and carboxy-terminal sequences." Journal of Cell Science 112, no. 22 (November 15, 1999): 4163–71. http://dx.doi.org/10.1242/jcs.112.22.4163.
Full textWILLNOW, Thomas E., Joan M. MOEHRING, Noel M. INOCENCIO, Thomas J. MOEHRING, and Joachim HERZ. "The low-density-lipoprotein receptor-related protein (LRP) is processed by furin in vivo and in vitro." Biochemical Journal 313, no. 1 (January 1, 1996): 71–76. http://dx.doi.org/10.1042/bj3130071.
Full textDahms, Sven O., Marcelino Arciniega, Torsten Steinmetzer, Robert Huber, and Manuel E. Than. "Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism." Proceedings of the National Academy of Sciences 113, no. 40 (September 19, 2016): 11196–201. http://dx.doi.org/10.1073/pnas.1613630113.
Full textBinley, James M., Rogier W. Sanders, Aditi Master, Charmagne S. Cayanan, Cheryl L. Wiley, Linnea Schiffner, Bruce Travis, et al. "Enhancing the Proteolytic Maturation of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins." Journal of Virology 76, no. 6 (March 15, 2002): 2606–16. http://dx.doi.org/10.1128/jvi.76.6.2606-2616.2002.
Full textLISSITZKY, Jean-Claude, José LUIS, Jon Scott MUNZER, Suzanne BENJANNET, Francis PARAT, Michel CHRÉTIEN, Jacques MARVALDI, and Nabil Georges SEIDAH. "Endoproteolytic processing of integrin pro-α subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7." Biochemical Journal 346, no. 1 (February 8, 2000): 133–38. http://dx.doi.org/10.1042/bj3460133.
Full textZorgati, Habiba, Mårten Larsson, Weitong Ren, Adelene Y. L. Sim, Jan Gettemans, Jonathan M. Grimes, Wenfei Li, and Robert C. Robinson. "The role of gelsolin domain 3 in familial amyloidosis (Finnish type)." Proceedings of the National Academy of Sciences 116, no. 28 (June 26, 2019): 13958–63. http://dx.doi.org/10.1073/pnas.1902189116.
Full textBERGERON, Eric, Ajoy BASAK, Etienne DECROLY, and Nabil G. SEIDAH. "Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage." Biochemical Journal 373, no. 2 (July 15, 2003): 475–84. http://dx.doi.org/10.1042/bj20021630.
Full textBonod-Bidaud, Christelle, Mickaël Beraud, Elisabeth Vaganay, Frédéric Delacoux, Bernard Font, David J. S. Hulmes, and Florence Ruggiero. "Enzymatic cleavage specificity of the proα1(V) chain processing analysed by site-directed mutagenesis." Biochemical Journal 405, no. 2 (June 27, 2007): 299–306. http://dx.doi.org/10.1042/bj20070051.
Full textRaghunath, M., E. A. Putnam, T. Ritty, D. Hamstra, E. S. Park, M. Tschodrich-Rotter, R. Peters, A. Rehemtulla, and D. M. Milewicz. "Carboxy-terminal conversion of profibrillin to fibrillin at a basic site by PACE/furin-like activity required for incorporation in the matrix." Journal of Cell Science 112, no. 7 (April 1, 1999): 1093–100. http://dx.doi.org/10.1242/jcs.112.7.1093.
Full textSolovyeva, N. I., T. A. Gureeva, O. S. Timoshenko, T. A. Moskvitina, and E. V. Kugaevskaya. "Furin as proprotein convertase and its role in normal and pathological biological processes." Biomeditsinskaya Khimiya 62, no. 6 (2016): 609–21. http://dx.doi.org/10.18097/pbmc20166206609.
Full textGuimont, Philippe, Francine Grondin, and Claire M. Dubois. "Sox9-dependent transcriptional regulation of the proprotein convertase furin." American Journal of Physiology-Cell Physiology 293, no. 1 (July 2007): C172—C183. http://dx.doi.org/10.1152/ajpcell.00349.2006.
Full textXiang, Yan, and Bernard Moss. "Molluscum Contagiosum Virus Interleukin-18 (IL-18) Binding Protein Is Secreted as a Full-Length Form That Binds Cell Surface Glycosaminoglycans through the C-Terminal Tail and a Furin-Cleaved Form with Only the IL-18 Binding Domain." Journal of Virology 77, no. 4 (February 15, 2003): 2623–30. http://dx.doi.org/10.1128/jvi.77.4.2623-2630.2003.
Full textKomoto, Satoshi, Mitsutaka Wakuda, Tomihiko Ide, Gen Niimi, Yoshimasa Maeno, Kyoko Higo-Moriguchi, and Koki Taniguchi. "Modification of the trypsin cleavage site of rotavirus VP4 to a furin-sensitive form does not enhance replication efficiency." Journal of General Virology 92, no. 12 (December 1, 2011): 2914–21. http://dx.doi.org/10.1099/vir.0.033886-0.
Full textSpencer, J. D., N. C. J. Gibbons, M. Böhm, and K. U. Schallreuter. "The Ca2+-Binding Capacity of Epidermal Furin Is Disrupted by H2O2-Mediated Oxidation in Vitiligo." Endocrinology 149, no. 4 (January 3, 2008): 1638–45. http://dx.doi.org/10.1210/en.2007-1317.
Full textKappert, Kai, Vesna Furundzija, Jan Fritzsche, Christian Margeta, Janine Krüger, Heike Meyborg, Eckart Fleck, and Philipp Stawowy. "Integrin cleavage regulates bidirectional signalling in vascular smooth muscle cells." Thrombosis and Haemostasis 103, no. 03 (2010): 556–63. http://dx.doi.org/10.1160/th09-07-0478.
Full textHipp, Madeleine, Uzi Gileadi, Dawn Sheperd, Caetano Reis e Sousa, and Vincenzo Cerundolo. "Processing of human TLR7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes. (P1244)." Journal of Immunology 190, no. 1_Supplement (May 1, 2013): 138.20. http://dx.doi.org/10.4049/jimmunol.190.supp.138.20.
Full textKeil, Günther M., Constanze Höhle, Katrin Giesow, and Patricia König. "Engineering Glycoprotein B of Bovine Herpesvirus 1 To Function as Transporter for Secreted Proteins: a New Protein Expression Approach." Journal of Virology 79, no. 2 (January 15, 2005): 791–99. http://dx.doi.org/10.1128/jvi.79.2.791-799.2005.
Full textDuda, Anja, Annett Stange, Daniel Lüftenegger, Nicole Stanke, Dana Westphal, Thomas Pietschmann, Scott W. Eastman, Maxine L. Linial, Axel Rethwilm, and Dirk Lindemann. "Prototype Foamy Virus Envelope Glycoprotein Leader Peptide Processing Is Mediated by a Furin-Like Cellular Protease, but Cleavage Is Not Essential for Viral Infectivity." Journal of Virology 78, no. 24 (December 15, 2004): 13865–70. http://dx.doi.org/10.1128/jvi.78.24.13865-13870.2004.
Full textWool-Lewis, Rouven J., and Paul Bates. "Endoproteolytic Processing of the Ebola Virus Envelope Glycoprotein: Cleavage Is Not Required for Function." Journal of Virology 73, no. 2 (February 1, 1999): 1419–26. http://dx.doi.org/10.1128/jvi.73.2.1419-1426.1999.
Full textPLAIMAUER, Barbara, Gabriele MOHR, Waltraud WERNHART, Michèle HIMMELSPACH, Friedrich DORNER, and Uwe SCHLOKAT. "‘Shed’ furin: mapping of the cleavage determinants and identification of its C-terminus." Biochemical Journal 354, no. 3 (March 8, 2001): 689–95. http://dx.doi.org/10.1042/bj3540689.
Full textCarattino, Marcelo D., Gunhild M. Mueller, Lawrence G. Palmer, Gustavo Frindt, Anna C. Rued, Rebecca P. Hughey, and Thomas R. Kleyman. "Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease." American Journal of Physiology-Renal Physiology 307, no. 9 (November 1, 2014): F1080—F1087. http://dx.doi.org/10.1152/ajprenal.00157.2014.
Full textBronnimann, Matthew P., Christine M. Calton, Samantha F. Chiquette, Shuaizhi Li, Mingfeng Lu, Janice A. Chapman, Kristin N. Bratton, Angela M. Schlegel, and Samuel K. Campos. "Furin Cleavage of L2 during Papillomavirus Infection: Minimal Dependence on Cyclophilins." Journal of Virology 90, no. 14 (April 27, 2016): 6224–34. http://dx.doi.org/10.1128/jvi.00038-16.
Full textKhodarovich, Yu M., E. V. Konovalova, A. A. Schulga, S. M. Deyev, and R. V. Petrov. "Removal of the translocation domain and the furin cleavage site decreases the relative hepatotoxicity of the targeted antitumor toxins." Доклады Академии наук 489, no. 2 (November 20, 2019): 209–12. http://dx.doi.org/10.31857/s0869-56524892209-212.
Full textBISSONNETTE, Lyne, Gabriel CHAREST, Jean-Michel LONGPRÉ, Pierre LAVIGNE, and Richard LEDUC. "Identification of furin pro-region determinants involved in folding and activation." Biochemical Journal 379, no. 3 (May 1, 2004): 757–63. http://dx.doi.org/10.1042/bj20031902.
Full textBestle, Dorothea, Miriam Ruth Heindl, Hannah Limburg, Thuy Van Lam van, Oliver Pilgram, Hong Moulton, David A. Stein, et al. "TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells." Life Science Alliance 3, no. 9 (July 23, 2020): e202000786. http://dx.doi.org/10.26508/lsa.202000786.
Full textKlimstra, William B., Natasha L. Tilston-Lunel, Sham Nambulli, James Boslett, Cynthia M. McMillen, Theron Gilliland, Matthew D. Dunn, et al. "SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients." Journal of General Virology 101, no. 11 (November 1, 2020): 1156–69. http://dx.doi.org/10.1099/jgv.0.001481.
Full textNegahdaripour, Manica, Mohammad Reza Rahbar, Zahra Mosalanejad, and Ahmad Gholami. "Theta-Defensins to Counter COVID-19 as Furin Inhibitors: In Silico Efficiency Prediction and Novel Compound Design." Computational and Mathematical Methods in Medicine 2022 (February 9, 2022): 1–15. http://dx.doi.org/10.1155/2022/9735626.
Full textLaprise, Marie-Hélène, Francine Grondin, Pauline Cayer, Patrick P. McDonald, and Claire M. Dubois. "Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates." Blood 100, no. 10 (November 15, 2002): 3578–87. http://dx.doi.org/10.1182/blood.v100.10.3578.
Full textWiens, Mayim E., and Jason G. Smith. "Alpha-Defensin HD5 Inhibits Furin Cleavage of Human Papillomavirus 16 L2 To Block Infection." Journal of Virology 89, no. 5 (December 24, 2014): 2866–74. http://dx.doi.org/10.1128/jvi.02901-14.
Full textRoy, Sourav, Prithwi Ghosh, Abhirup Bandyopadhyay, and Sankar Basu. "Capturing a Crucial ‘Disorder-to-Order Transition’ at the Heart of the Coronavirus Molecular Pathology—Triggered by Highly Persistent, Interchangeable Salt-Bridges." Vaccines 10, no. 2 (February 16, 2022): 301. http://dx.doi.org/10.3390/vaccines10020301.
Full textJean, F., A. Basak, J. DiMaio, N. G. Seidah, and C. Lazure. "An internally quenched fluorogenic substrate of prohormone convertase 1 and furin leads to a potent prohormone convertase inhibitor." Biochemical Journal 307, no. 3 (May 1, 1995): 689–95. http://dx.doi.org/10.1042/bj3070689.
Full textNeumann, Gabriele, Heinz Feldmann, Shinji Watanabe, Igor Lukashevich, and Yoshihiro Kawaoka. "Reverse Genetics Demonstrates that Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Essential for Replication in Cell Culture." Journal of Virology 76, no. 1 (January 1, 2002): 406–10. http://dx.doi.org/10.1128/jvi.76.1.406-410.2002.
Full textJohnson, Bryan A., Xuping Xie, Adam L. Bailey, Birte Kalveram, Kumari G. Lokugamage, Antonio Muruato, Jing Zou, et al. "Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis." Nature 591, no. 7849 (January 25, 2021): 293–99. http://dx.doi.org/10.1038/s41586-021-03237-4.
Full text