Dissertations / Theses on the topic 'Functional systems analysis'
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Schmelich, Volker, and Rainer Alt. "Functional Analysis of Open Source ERP Systems – An Exploratory Analysis." Universitätsbibliothek Leipzig, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-81833.
Full textSchmelich, Volker, and Rainer Alt. "Functional Analysis of Open Source ERP Systems – An Exploratory Analysis." Universität Leipzig, 2008. https://ul.qucosa.de/id/qucosa%3A11328.
Full textMacDonell, Stephen Gerard. "Quantitative functional complexity analysis of commercial software systems." Thesis, University of Cambridge, 1993. https://www.repository.cam.ac.uk/handle/1810/270422.
Full textTan, Sofia. "Enhanced functional analysis system technique for managing complex engineering projects." Diss., Rolla, Mo. : University of Missouri-Rolla, 2007. http://scholarsmine.umr.edu/thesis/pdf/Tan_09007dcc803c4e70.pdf.
Full textVita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed November 27, 2007) Includes bibliographical references (p. 27-29).
Adams, Anne Edith. "Understanding the skill of functional task analysis." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37313.
Full textNayfeh, Jamal Faris. "Nonlinear dynamics of composite plates and other physical systems." Diss., This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-07282008-135756/.
Full textXu, Yiwen. "Reliability Analysis and Optimization of Systems Containing Multi-Functional Entities." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/594927.
Full textCole, David Michael. "Functional network analysis of human brain systems under pharmacological modulation." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/10933.
Full textBell, Jonathan. "Interpretation of simulation for model-based design analysis of engineered systems." Thesis, Aberystwyth University, 2006. http://hdl.handle.net/2160/05880836-32b8-4f65-abfe-9b0ecf16cc42.
Full textChang, Ken Kai-fu 1973. "Simulation of nonlinear optic-fibre communication systems using Volterra series transfer function techniques." Monash University, Dept. of Electrical and Computer Systems Engineering, 2002. http://arrow.monash.edu.au/hdl/1959.1/7758.
Full textZhou, Rensheng. "Degradation modeling and monitoring of engineering systems using functional data analysis." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/45897.
Full textOscarsson, Joakim. "Functional Safety in Co-operative Driving using Systems-Theoretic Process Analysis." Thesis, KTH, Maskinkonstruktion (Inst.), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-201094.
Full textCo-operative driving is the phenomenon of connected road vehicles exchanging information to achieve safer and more efficient traffic. It is a convoluted context, which gives the topic of functional safety new complex angles. It can be automated, and as autonomous vehicles are dependent on reliable information for decision making, the issue of trusting data received over co-operation communication channels is raised. Disregarding the topic of security, there is still the possibility of failures in external vehicles causing incoming transmissions to be untrustworthy. In this thesis, it is shown that premises regarding levels of external trust can have significant impacts on the final architecture. It is also shown that neither fully trusting, nor not trusting data received over co-operation communication channels is the best option, when considering safety, usage of communication potential and cost. Because of the complexity of co-operative driving, the analyses are performed using the new and promising method of Systems-Theoretic process analyses (STPA). The current best practice of automotive functional safety is to comply with the domain specific ISO 26262 standard, which does not provide a natural way of implementing STPA. Therefore, this thesis also presents a development process which utilises the benefits of STPA, while complying to the ISO 26262 standard. STPA has the greatest potential during the product development at system level, though other uses have also been identified. STPA is a generic analysis method, which has previously not been used in the context of cooperative driving. This thesis therefor begins by validating the applicability of STPA in this specific context. The evaluation is performed using a real world case study connected to KTH’s participation in the Grand Cooperative Driving Challenge - a competition by i-GAME to speed up the implementation of co-operative driving in Europe. The validity of the method when applied to this context is strengthened by multiple analysts, the KTH co-operative driving development team, client approval of results and academic reviews.
Hayashi, Koji. "Functional Analysis of Mammalian Cytochromes P450 by Using Heterologus Expression Systems." Kyoto University, 2001. http://hdl.handle.net/2433/150789.
Full textKu, Hyunchul. "Behavioral modeling of nonlinear RF power amplifiers for digital wireless communication systems with implications for predistortion linearization systems." Diss., Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-04052004-180035/unrestricted/ku%5Fhyunchul%5F200312%5Fphd.pdf.
Full textLeung, Tsui-shan. "A functional analysis of GIS for slope management in Hong Kong /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22032447.
Full textSaadatmand, Mehrdad. "Preservation of Extra-Functional Properties in Embedded Systems Development." Doctoral thesis, Mälardalens högskola, Inbyggda system, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-27300.
Full textCHESS
MBAT
ITS-EASY
Rieger, Karl. "Analysis and control of infinite dimensional systems a geometric and functional analytic approach." Aachen Shaker, 2008. http://d-nb.info/993663737/04.
Full textFlöttmann, Max. "Functional analysis of High-Throughput data for dynamic modeling in eukaryotic systems." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2013. http://dx.doi.org/10.18452/16809.
Full textThe behavior of all biological systems is governed by numerous regulatory mechanisms, acting on different levels of time and space. The study of these regulations has greatly benefited from the immense amount of data that has become available from high-throughput experiments in recent years. To interpret this mass of data and gain new knowledge about studied systems, mathematical modeling has proven to be an invaluable method. Nevertheless, before data can be integrated into a model it needs to be aggregated, analyzed, and the most important aspects need to be extracted. We present four Systems Biology studies on different cellular organizational levels and in different organisms. Additionally, we describe two software applications that enable easy comparison of data and model results. We use these in two of our studies on the mitogen-activated-protein (MAP) kinase signaling in Saccharomyces cerevisiae to generate model alternatives and adapt our representation of the system to biological data. In the two remaining studies we apply Bioinformatic methods to analyze two high-throughput time series on proteins and mRNA expression in mammalian cells. We combine the results with network data and use annotations to identify modules and pathways that change in expression over time to be able to interpret the datasets. In case of the human somatic cell reprogramming (SCR) system this analysis leads to the generation of a probabilistic Boolean model which we use to generate new hypotheses about the system. In the last system we examined, the infection of mammalian (Canis familiaris) cells by the influenza A virus, we find new interconnections between host and virus and are able to integrate our data with existing networks. In summary, many of our findings show the importance of data integration into mathematical models and the high degree of connectivity between different levels of regulation.
Shah, Riddhi. "Functional analysis of Group 2 chaperonins from archaeal species in E. coli." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/4957/.
Full textHanauer, Maria [Verfasser], and Peter [Akademischer Betreuer] Poschlod. "Comparative ecological and functional analysis of grazing systems / Maria Hanauer. Betreuer: Peter Poschlod." Regensburg : Universitätsbibliothek Regensburg, 2016. http://d-nb.info/1085551873/34.
Full textSharif, Asif. "A functional analysis of building procurement systems and strategies in an international context." Thesis, Nottingham Trent University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337534.
Full textHirose, Takayuki. "Envisioning Emergent Behaviors of Socio-Technical Systems Based on Functional Resonance Analysis Method." Kyoto University, 2020. http://hdl.handle.net/2433/259040.
Full textKyoto University (京都大学)
0048
新制・課程博士
博士(工学)
甲第22772号
工博第4771号
新制||工||1746(附属図書館)
京都大学大学院工学研究科機械理工学専攻
(主査)教授 椹木 哲夫, 教授 松原 厚, 教授 小森 雅晴
学位規則第4条第1項該当
Fujita, Miki. "FUNCTIONAL ANALYSIS OF GENE PRODUCTS OF PLANT VIRUSES BY USING PROTEIN EXPRESSION SYSTEMS." Kyoto University, 2000. http://hdl.handle.net/2433/181036.
Full text0048
新制・課程博士
博士(農学)
甲第8407号
農博第1091号
新制||農||797(附属図書館)
学位論文||H12||N3364(農学部図書室)
UT51-2000-F311
京都大学大学院農学研究科応用生物科学専攻
(主査)教授 古澤 巌, 教授 久野 英二, 教授 津田 盛也
学位規則第4条第1項該当
Vasconcelos, Pedro B. "Space cost analysis using sized types." Thesis, University of St Andrews, 2008. http://hdl.handle.net/10023/564.
Full textAnders, Shilo H. "Projecting trajectories of functional use for a new technology the electronic ICU /." Columbus, Ohio : Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1213369071.
Full textKästner, Christopher Niels. "Functional analysis and single-molecule fluorescence spectroscopy of citrate transport systems from Klebsiella pneumoniae /." Zürich, 2001. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=14370.
Full textTisell, Claes. "Integration of database technology and multibody system analysis." Doctoral thesis, Stockholm, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3041.
Full textLeung, Tsui-shan, and 梁翠珊. "A functional analysis of GIS for slope management in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31223072.
Full textAnkers, John-Mark. "An interdisciplinary analysis of physical and functional interactions between the NF-kappaB and E2F systems." Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501724.
Full textPrince, Samantha. "Mutation analysis of Wolfram syndrome patients and functional study of the wolframin protein." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3760/.
Full textFlodmark, Erik, and Carl Sävendahl. "Managing a digital transformation : A case study of digitizing functional operations in a sociotechnical system." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-300385.
Full textSverige har ett övergripande mål att vara det ledande landet när det gäller att dra nytta av digitaliseringens möjligheter inom sjukvården. Dessutom understryker Vetenskapsrådet att det är centralt för förbättrad sjukvård att öka antalet kliniska studier i landet. Följaktligen, med tanke på behovet av en ökad operativ effektivitet, identifierade författarna det av intresse att studera digitalisering av branschen. Studien tillämpar således ett kognitivt ramverk för arbetsanalys i syfte att undersöka de potentiella fördelarna eller riskerna med att digitalisera den funktionella verksamheten hos en kontrakthanteringsavdelning för kliniska studier vid ett stort svenskt universitetssjukhus. Målsättningen är därefter att ta fram lämpliga egenskaper som är nödvändiga att beakta vid hanteringen av den digitala transformationen. Kontrakthanteringsavdelningen fanns att inneha brister i sina arbetsprocesser gällande transparens, effektivitet och standardisering vilket hindrar målet avseende ökad klinisk aktivitet. Studien visade att en digital transformation skulle vara nödvändig för att motverka dessa brister, samt för att möjliggöra en uppskalning av organisationen. Ett annat specifikt förbättringsområde som skulle underlättas av en digital transformation visade sig vara förbättrad synkronisering mellan arbetsprocesser. Vidare fann studien att de mest kritiska egenskaperna nödvändiga att beakta, vid hantering av en digital transformation, skulle vara interoperabilitet, kvalitet, anpassningsförmåga och användbarhet. Dessutom är säkerhet en egenskap som visat sig vara kritisk att beakta vid digitalisering då kontrakthanteringsavdelningen lyder under stränga lagar och föreskrifter beträffande etik och patientsäkerhet. Resultaten bidrar till forskningsområdet cognitive systems engineering. Studien har dock vissa begränsningar gällande tillförlitlighet och generaliserbarhet. Resultaten är baserade på en enfallstudie, som eventuellt inte är representativ för branschen i allmänhet eller för universitetssjukhus i synnerhet. Dessutom, då ingen digitaliseringsinsats utfördes under studien är de viktiga egenskaperna att beakta i den digitala transformationen enbart spekulativa. Således är det i framtida forskning viktigt att studera en faktisk implementation och då studera om föreslagna beaktanden är tillräckliga för att utnyttja digitaliseringens möjligheter.
Abeto, Benjamin. "An Application of Systems Engineering to Analyze the Interagency Coordination Aspect of Counter Trafficking and Terrorism." Thesis, Monterey, California: Naval Postgraduate School, 2012. http://hdl.handle.net/10945/7286.
Full textPaszkowski-Rogacz, Maciej. "Integration and analysis of phenotypic data from functional screens." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-63063.
Full textVictor, Sjölin. "Putting a FRAMe on the VTS : A systems analysis of the Vessel Traffic Service using the Functional Resonance Analysis Method." Thesis, Linköpings universitet, Institutionen för datavetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-96395.
Full textPoirel, Christopher L. "Bridging Methodological Gaps in Network-Based Systems Biology." Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/23899.
Full textPh. D.
Ralston, Jonathon Carey. "Identification of a class of nonlinear systems in the non-Gaussian input case." Thesis, Queensland University of Technology, 1996. https://eprints.qut.edu.au/36000/2/36000_Digitised_Thesis.pdf.
Full textChanda, Michael, Julee DiPlacido, John Dougherty, Richard Egan, John Kelly, Trent Kingery, Daniel Liston, et al. "Proposed functional architecture and associated benefits analysis of a common ground control station for Unmanned Aircraft Systems." Thesis, Monterey, California. Naval Postgraduate School, 2010. http://hdl.handle.net/10945/6949.
Full textThe proliferation of Unmanned Aerial Systems (UASs) and lack of mandated standards has led to unique Unmanned Aerial Vehicle (UAV) and Ground Control Station (GCS) designs. A former Under Secretary of Defense for Acquisition, Technology, and Logistics, stated in an Acquisition Decision Memorandum (ADM) that UAS GCS commonality could reduce manpower, procurement, sustainment and life cycle costs. While the ADM provided an impetus for commonality, it did not define a path. This project defines a common GCS functional architecture that provides the first steps on the path to UAS commonality. Stakeholder documentation was analyzed to identify areas of greatest concern and to examine previous efforts in this domain. Then, a tailored systems engineering process was employed to develop a new set of requirements which includes a common Air Vehicle Operator (AVO) Human-Machine Interface. These requirements enabled the creation of an innovative functional architecture for a common GCS concept. The utilization of this architecture has multiple operational, logistical, and financial benefits. This project quantified AVO training cost benefits and found that implementation of the common GCS architecture in accordance with the derived requirements will benefit the Department of Defense through reduced Operations and Support costs and increased operational capability.
Ogris, Christoph. "Global functional association network inference and crosstalk analysis for pathway annotation." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-146703.
Full textAt the time of the doctoral defense, the following paper was unpublished and had a status as follows: Paper 2: Manuscript.
Cubuk, Cankut. "Modeling Functional Modules Using Statistical and Machine Learning Methods." Doctoral thesis, Universitat Politècnica de València, 2020. http://hdl.handle.net/10251/156175.
Full text[CA] La comprensió dels aspectes de la funcionalitat de les cèl·lules que compten per als mecanismes de les malalties és el major repte de la medicina personalitzada. Malgrat la disponibilitat creixent de les dades de genòmica i transcriptómica, continua existint una notable bretxa entre la detecció de les pertorbacions en l'expressió de gens i la comprensió de la seua contribució en els mecanismes moleculars que últimament tenen relació important amb el fenotip estudiat. Al llarg de l'última dècada, diferents models computacionals i matemàtics s'han proposat per a l'anàlisi de les rutes. No obstant això, aquests models no tenen en compte els mecanismes dinàmics de les rutes com l'estructura i les interaccions entre gens i proteïnes. En aquesta tesi doctoral, presente dos models matemàtics lleugerament diferents, per a integrar les dades transcriptómicos massius d'humà amb un coneixement previ de de les rutes de senyalització i metabòliques per a estimar les activitats mecàniques que estan darrere d'aqueixes rutes (MPAs). Les MPAs són variables contínues amb valors de nivell individual que poden ser usades amb els models d'aprenentatge de màquines i mètodes estadístics per a determinar els biomarcadores que podem usar per als diagnòstics primerencs i la classificació de subtipus de malalties, a més de poder suggerir les dianes terapèutiques potencials per a les intervencions individualitzades. L'objectiu global és desenvolupar nous i avançats enfocaments de la biologia de sistemes per a proposar unes hipòtesis funcionals que ens ajuden a entendre i interpretar els mecanismes complexos de les malalties. Aquests mecanismes són crucials per a millorar els tractaments personalitzats i predir els resultats clínics. En primer lloc, vaig contribuir al desenvolupament d'un mètode que està dissenyat per a extraure les subrutas elementals des de la ruta de senyalització amb les seues activitats estimades. Posteriorment, aquest algorisme s'ha adaptat als mòduls metabòlics i s'ha implementat com una eina web. Finalment, el mètode ha revelat un panorama metabòlic per a una llista completa de diferents tipus de càncers. En aquest estudi, vaig analitzar el perfil metabòlic de 25 tipus de càncer diferents i es va validar el mètode usant diversos enfocaments computacionals i experimentals. Cada mètode desenvolupat en aquesta tesi ha sigut enfrontat a altres mètodes similars existents, avaluats per les seues sensibilitats i especificitats, experimentalment validats quan va ser possible i usats per a predir resultats clínics de diversos tipus de càncers. La investigació descrita en aquesta tesi i els resultats obtinguts van ser publicats en diferents revistes arbitrades que estan relacionades amb el càncer i biologia de sistemes, i també en els periòdics nacionals.
[EN] Understanding the aspects of the cell functionality that account for disease or drug action mechanisms is the main challenge for precision medicine. In spite of the increasing availability of genomic and transcriptomic data, there is still a gap between the detection of perturbations in gene expression and the understanding of their contribution to the molecular mechanisms that ultimately account for the phenotype studied. Over the last decade, different computational and mathematical models have been proposed for pathway analysis. However, they are not taking into account the dynamic mechanisms contained by pathways as represented in their layout and the interactions between genes and proteins. In this thesis, I present two slightly different mathematical models to integrate human transcriptomic data with prior knowledge of signalling and metabolic pathways to estimate the Mechanistic Pathway Activities (MPAs). MPAs are continuous and individual level values that can be used with machine learning and statistical methods to determine biomarkers for the early diagnosis and subtype classification of the diseases, and also to suggest potential therapeutic targets for individualized therapeutic interventions. The overall objective is, developing new and advanced systems biology approaches to propose functional hypotheses that help us to understand and interpret the complex mechanism of the diseases. These mechanisms are crucial for robust personalized drug treatments and predict clinical outcomes. First, I contributed to the development of a method which is designed to extract elementary sub-pathways from a signalling pathway and to estimate their activity. Second, this algorithm adapted to metabolic modules and it is implemented as a webtool. Third, the method used to reveal a pan-cancer metabolic landscape. In this study, I analyzed the metabolic module profile of 25 different cancer types and the method is also validated using different computational and experimental approaches. Each method developed in this thesis was benchmarked against the existing similar methods, evaluated for their sensitivity and specificity, experimentally validated when it is possible and used to predict clinical outcomes of different cancer types. The research described in this thesis and the results obtained were published in different systems biology and cancer-related peer-reviewed journals and also in national newspapers.
Cubuk, C. (2020). Modeling Functional Modules Using Statistical and Machine Learning Methods [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/156175
TESIS
Madison, Guy. "Functional modelling of the human timing mechanism." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5012-1/.
Full textZhou, Mingyan. "Structural and functional analysis of a novel organic cation/monoamine transporter PMAT in the SLC29 family /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/7979.
Full textHölzer, Stefanie. "Functional analysis of type III secretion systems in Salmonella enterica = Funktionelle Analyse von Typ-III-Sekretionssystemen in Salmonella enterica." kostenfrei, 2010. http://d-nb.info/1001858735/34.
Full textKantanantha, Nantachai. "Crop decision planning under yield and price uncertainties." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/24676.
Full textCommittee Co-Chair: Griffin, Paul; Committee Co-Chair: Serban, Nicoleta; Committee Member: Liang, Steven; Committee Member: Sharp, Gunter; Committee Member: Tsui, Kwok-Leung
Sullivan, Lisa, Lennard Cannon, Ronel Reyes, Kitan Bae, James Colgary, Nick Minerowicz, Chris Leong, et al. "Rapid Response Command and Control (R2C2): a systems engineering analysis of scaleable communications for Regional Combatant Commanders." Monterey, California. Naval Postgraduate School, 2006. http://hdl.handle.net/10945/7267.
Full textDisaster relief operations, such as the 2005 Tsunami and Hurricane Katrina, and wartime operations, such as Operation Enduring Freedom and Operation Iraqi Freedom, have identified the need for a standardized command and control system interoperable among Joint, Coalition, and Interagency entities. The Systems Engineering Analysis Cohort 9 (SEA-9) Rapid Response Command and Control (R2C2) integrated project team completed a systems engineering (SE) process to address the military’s command and control capability gap. During the process, the R2C2 team conducted mission analysis, generated requirements, developed and modeled architectures, and analyzed and compared current operational systems versus the team’s R2C2 system. The R2C2 system provided a reachback capability to the Regional Combatant Commander’s (RCC) headquarters, a local communications network for situational assessments, and Internet access for civilian counterparts participating in Humanitarian Assistance/Disaster Relief operations. Because the team designed the R2C2 system to be modular, analysis concluded that the R2C2 system was the preferred method to provide the RCC with the required flexibility and scalability to deliver a rapidly deployable command and control capability to perform the range of military operations.
Flöttmann, Max [Verfasser], Edda [Akademischer Betreuer] Klipp, Andreas [Akademischer Betreuer] Herrmann, and Ralf [Akademischer Betreuer] Mrowka. "Functional analysis of High-Throughput data for dynamic modeling in eukaryotic systems / Max Flöttmann. Gutachter: Edda Klipp ; Andreas Herrmann ; Ralf Mrowka." Berlin : Humboldt Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2013. http://d-nb.info/1041679793/34.
Full textZiv, Nicolas. "Enrichment of functional analysis for the construction sector by the integration of systems engineering and constructibility : application to the multifunctional metro." Thesis, Paris Est, 2018. http://www.theses.fr/2018PESC1065/document.
Full textObjectives of the thesis is to enrich Functional Analysis, a design method oriented on the definition of functions, by the integration of two methodological corpuses: Constructability and Systems Engineering in order to adapt it to complex construction products. The enriched method is used and applied on an innovative concept: the multifunctional metro. This new concept consists in the integration of new functions in a metro system: not only transport people but also energy, information, wastes, merchandises, water etc. in order to answer to several city needs with a unique infrastructure. In the introduction, after having describe challenges faced by the construction industry, we highlight that Functional Analysis has been used extensively in other industries to face similar issues. However, its application in the construction industry is limited due to particularities of the construction industry: each project is unique, construction projects are complex and that needs construction projects answer consists in adapting space in order to carry human or related activities. The identification of such particularities have led on one hand, to the consideration of constructability concepts and principles in Functional Analysis to better integrate development constraints of each project in the product development. On the other hand, to the consideration of Systems Engineering, a methodological corpus which objective is to manage complexity of projects. Firstly, Functional Analysis, Constructability and Systems Engineering corpuses are presented and issues are identified in these three methods either to adapt them to complex construction projects for their integration. Constructability notably, is improved with the integration of constraints from Design and Planning phases and a proposition is presented to shift from Constructability to Constructibility. Systems Engineering for its part is adapted by the integration of spatial characteristics of systems. A SysML tool (Systems Modeling Language) has been developed and linked with a BIM modeling tool to improve the capacity to model and verify requirements related to construction systems. The Constructibility matrix, a tool to ease the implementation of constructibility has also been developed.Secondly, Functional Analysis enriched by methodological inputs and tools related to the construction industry is applied. Case studies concern two different phases (planning and design) in two different projects where multifunctionnality concepts have been investigated: the 5th metro line of Lyon where the evaluation of the integration of new functions in the metro line have been studied. And the line 16 of the Greater Paris Project where the integration of a broadband network was the opportunity to study the integration of a new function more in detail (transport information). In conclusion we shall suggest some ways forward by outlining avenues for further researches: how to measure constructibility criteria at different systemic levels is a challenge on which we give some ways to follow. The application and adaptation of Systems Engineering to the construction industry remains to be better investigated and we give some further research indications, particularly on the integration with BIM (Building Information Modeling) methods. We also present how the use of MBSE (Model-Based Systems Engineering) techniques and Data Science could lead to the automation of some design activities which could enrich Functional Analysis methods. Insights on the organization of the profession and contractual issues are proposed and would require more researches to enable implementation of the presented methodology in projects
Pedott, Alexandre Homsi. "Análise de dados funcionais aplicada ao estudo de repetitividade e reprodutividade : ANOVA das distâncias." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/24726.
Full textThis work presents a method to analyze a measurement system's performance in a functional data analysis context, based on repeatability and reproducibility studies. Functional data are a collection of data points organized as a profile or curve. The proposed method contributes to the state of the art on measurement system analysis. The method is an alternative to traditional methods often used mistakenly, leading to deterioration in the quality of products monitored through functional responses. In the proposed method we adapt hypothesis tests and one-way and two-way ANOVA to be used in measurement system analysis. The method is grounded on the use of distances between curves. For that matter the Hausdorff distance was chosen as a measure of proximity between curves. Three ANOVA approaches were proposed and applied in a simulated repeatability and reproducibility study. The study was structured to analyze scenarios in which the measurement system was approved or rejected. The proposed method was named ANOVA of the distances.
Boyanova, Desislava Veselinova Verfasser], and Thomas [Akademischer Betreuer] [Dandekar. "Systems biological analysis of the platelet proteome and applications of functional module search in proteome networks / Desislava Veselinova Boyanova. Betreuer: Thomas Dandekar." Würzburg : Universität Würzburg, 2013. http://d-nb.info/1102820911/34.
Full textBoyanova, Desislava Veselinova [Verfasser], and Thomas [Akademischer Betreuer] Dandekar. "Systems biological analysis of the platelet proteome and applications of functional module search in proteome networks / Desislava Veselinova Boyanova. Betreuer: Thomas Dandekar." Würzburg : Universität Würzburg, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72165.
Full textFan-Osuala, Onochie. "Essays on Crowdfunding: Exploring the Funding and Post-funding Phases and Outcomes." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6834.
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