Journal articles: 'Frontal lobes'

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Fuster, Joaquin M. "Frontal lobes." Current Opinion in Neurobiology 3, no. 2 (April 1993): 160–65. http://dx.doi.org/10.1016/0959-4388(93)90204-c.

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Knopman, D. S. "Human Frontal Lobe Function Revealed." Journal of the International Neuropsychological Society 7, no. 5 (July 2001): 649. http://dx.doi.org/10.1017/s1355617701235127.

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All you ever wanted to know about the human frontal lobes seems to be contained in this multiauthored text, at least up to 1996 or 1997. The editors, Miller and Cummings, are acknowledged experts on the topic of human disorders of the frontal lobes. They have done a monumental job of collecting 53 authors and 34 chapters. The book is divided into five sections, frontal lobe neuroanatomy, frontal lobe neurochemistry and neurophysiology, frontal lobe neuropsychology, neurological diseases involving the frontal lobes, and psychiatric diseases involving the frontal lobes.

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Brown, R. "The Frontal Lobes." Journal of Neurology, Neurosurgery & Psychiatry 50, no. 7 (July 1, 1987): 954–55. http://dx.doi.org/10.1136/jnnp.50.7.954-b.

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Mirsky, Allan F. "The Frontal Lobes." Journal of Clinical Neurophysiology 4, no. 1 (January 1987): 89. http://dx.doi.org/10.1097/00004691-198701000-00011.

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Heilman, K. M. "The Frontal Lobes." Neurology 37, no. 2 (February 1, 1987): 358. http://dx.doi.org/10.1212/wnl.37.2.358.

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Wyke, Maria. "The frontal lobes." Behaviour Research and Therapy 25, no. 5 (1987): 437. http://dx.doi.org/10.1016/0005-7967(87)90030-1.

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Stuss, Donald T., and Michael P. Alexander. "Does Damage to the Frontal Lobes Produce Impairment in Memory?" Current Directions in Psychological Science 14, no. 2 (April 2005): 84–88. http://dx.doi.org/10.1111/j.0963-7214.2005.00340.x.

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There has long been controversy about the function of the frontal lobes in memory. Historically, in lesion studies, the frontal lobes were discussed as if they represented a single functional unit, and little attention was paid to possible regional differences. In a series of experiments involving patients with focal frontal lobe lesions, we have demonstrated that different frontal regions affect strategic memory processes in unique ways. In addition, some regions of the frontal lobes are involved in nonstrategic memory encoding, likely through actual involvement of the limbic memory regions or through the impact of processing deficits related to the specific mode of the information to be learned (e.g., language). These findings converge with those of functional imaging studies showing the dissociation of memory processes within the frontal lobes, and are indicative of the complex roles subserved by the frontal lobes. Future research will need to explore how the different functions within the frontal lobes influence other dynamic cognitive systems.

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Russell, Janice D., and Milton G. Roxanas. "Psychiatry and the Frontal Lobes." Australian & New Zealand Journal of Psychiatry 24, no. 1 (March 1990): 113–32. http://dx.doi.org/10.3109/00048679009062894.

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The frontal lobes of the brain have long been regarded as enigmatic in their function and perhaps should be considered even more so in states of dysfunction. Observed associations between structural lesions and psychiatric symptoms and the demonstration of disturbed function and morphology in the frontal lobes of individuals suffering from major psychiatric disorders have led to increased interest in this brain area. Psychiatrists have been particularly concerned with seeking the aetiogenesis of common diagnostic entities and this article attempts to synthesize the available facts. A brief overview of relevant biological data precedes a description of methods of neuropsychological testing and the clinical features arising from frontal lobe damage. A discussion of the role of the frontal lobes in some aspects of personality function follows. Neuropsychiatric features associated with known frontal lobe pathology are described, prefacing a discussion of those psychiatric conditions where an aetiological role for frontal lobe dysfunction has been proposed.

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Highley, J. Robin, Mary A. Walker, Margaret M. Esiri, Brendan McDonald, Paul J. Harrison, and Timothy J. Crow. "Schizophrenia and the frontal lobes." British Journal of Psychiatry 178, no. 4 (April 2001): 337–43. http://dx.doi.org/10.1192/bjp.178.4.337.

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BackgroundIt has been suggested that there is frontal lobe involvement in schizophrenia, and that it may be lateralised and gender-specific.AimsTo clarify the structure of the frontal lobes in schizophrenia in a postmortem series.MethodThe volume of white matter and cortical components of the frontal lobes was measured in brains of controls and patients with schizophrenia using planimetry and the Cavalieri principle. The components measured were: superior frontal gyrus, middle frontal gyrus, a composite of inferior frontal gyrus and orbito-frontal cortex, as well as total frontal lobe cortex and white matter. In addition, the anterior cingulate gyrus was measured.ResultsNo diagnosis, gender, diagnosis × side, diagnosis × gender or diagnosis × gender × side interactions were observed in the volume of any of the components, the grey matter as a whole or the white matter. No evidence for volumetric inter-group differences was found for the anterior cingulate gyrus.ConclusionsSuch structural abnormalities as are present in the frontal lobes are more subtle than straightforward alterations in tissue volume; they may include changes in shape and the pattern of gyral folding.

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Filoteo, J. Vincent, Scott Lauritzen, and W. Todd Maddox. "Removing the Frontal Lobes." Psychological Science 21, no. 3 (February 16, 2010): 415–23. http://dx.doi.org/10.1177/0956797610362646.

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Wechsler, Adam F. "The Frontal Lobes Revisited." Journal of Nervous and Mental Disease 176, no. 4 (April 1988): 252. http://dx.doi.org/10.1097/00005053-198804000-00011.

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Alexander, Michael P., D. Frank Benson, and Donald T. Stuss. "Frontal lobes and language." Brain and Language 37, no. 4 (November 1989): 656–91. http://dx.doi.org/10.1016/0093-934x(89)90118-1.

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Joseph, Jean-Paul. "The frontal lobes revisited." Neuropsychologia 25, no. 4 (January 1987): 743–44. http://dx.doi.org/10.1016/0028-3932(87)90069-8.

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Petrides, M. "Frontal lobes and behaviour." Current Opinion in Neurobiology 4, no. 2 (1994): 207–11. http://dx.doi.org/10.1016/0959-4388(94)90074-4.

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Prigatano, George P. "The frontal lobes revisited." Journal of Neurolinguistics 3, no. 1 (January 1988): 115–19. http://dx.doi.org/10.1016/0911-6044(88)90010-3.

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AHMED, Wegdan, Tahir OSMAN, Bünyamin ŞAHİN, and Amani ELFAKİ. "The effect of sex and age on cortical grey and white matter volumes of frontal lobe." Journal of Experimental and Clinical Medicine 38, no. 3 (April 23, 2021): 227–34. http://dx.doi.org/10.52142/omujecm.38.3.4.

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Grey matter (GM) of the frontal lobe carries out its complex function such as muscle control, speech, decision making, and self-control; while the white matter (WM) of frontal lobe is a major contributor to human brain enlargement and higher structural connectivity. This study was conducted to assess the effect of sex and age on grey and white matter volumes (GMV and WMV) of the frontal lobe and its gyri in healthy young adult Sudanese. The present study included 139 healthy Sudanese subjects (80 males and 59 females). Participant’s ages were ranging between 20-40 years. T1-weighted MR brain images with thickness 1mm were obtained. MR images of the subjects were analyzed using the automatic segmentation software (BrainSuite). GMV and WMV of frontal lobe and its gyri were estimated using the output data of the process of software. Males had greater GMV and WMV of the frontal lobes (251.18±31.80cm3 and 143.48±22.92cm3, respectively) and most of frontal lobe gyri (P<0.05). Change with age in GMV has been reported in the frontal lobes, superior frontal gyrus, pars orbitalis, orbitofrontal, and cingulate gyrus (P<0.05). Change with age in WM volumes has been found in the cingulate, precentral, and paracentral gyri (P<0.05). Sex has prominent effect on GMV and WMV of the frontal lobes and most of frontal lobe gyri, thus sex is a major contributor to GMV and WMV differences between individuals. Age effect GMV and WMV of most frontal lobe gyri, these findings confirm the continuation of maturation of frontal lobe until fourth decade. Assessing effect of sex and age on GM and WM in healthy adult has major importance to distinguish the normal brain from diseased.

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Thatcher, Robert W. "Psychopathology of early frontal lobe damage: Dependence on cycles of development." Development and Psychopathology 6, no. 4 (1994): 565–96. http://dx.doi.org/10.1017/s0954579400004697.

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AbstractA new theory of frontal lobe development is presented in which the role of the human frontal lobes during normal development and the psychopathological consequences of early frontal lobe injury are explored. Analyses of the development of human electroencephalograph (EEG) coherence indicate that there are oscillations and cyclic growth processes along the mediolateral and anterior-posterior planes of the brain. The cycles of EEG coherence are interpreted as repetitive sequences of increasing and decreasing synaptic effectiveness that reflects a convergence process that narrows the disparity between structure and function by slowly sculpting and reshaping the brain's microanatomy. This process is modeled as a developmental spiral staircase in which brain structures are periodically revisited resulting in stepwise increases in differentiation and integration. The frontal lobes play a crucial role because they are largely responsible for the selection and pruning of synaptic contacts throughout the postnatal period. A mathematical model of cycles of synaptic effectiveness is presented in which the frontal lobes behave as gentle synaptic “predators” whereas posterior cortical regions behave as synaptic “prey” in a periodic reorganization process. The psychopathological consequences of early frontal lobe damage are discussed in the context of this model.

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Binias, Bartosz, Dariusz Myszor, Sandra Binias, and Krzysztof A. Cyran. "Analysis of Relation between Brainwave Activity and Reaction Time of Short-Haul Pilots Based on EEG Data." Sensors 23, no. 14 (July 17, 2023): 6470. http://dx.doi.org/10.3390/s23146470.

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The purpose of this research is to examine and assess the relation between a pilot’s concentration and reaction time with specific brain activity during short-haul flights. Participants took part in one-hour long flight sessions performed on the FNPT II class flight simulator. Subjects were instructed to respond to unexpected events that occurred during the flight. The brainwaves of each participant were recorded with the Emotiv EPOC+ Scientific Contextual EEG device. The majority of participants showed a statistically significant, positive correlation between Theta Power in the frontal lobe and response time. Additionally, most subjects exhibited statistically significant, positive correlations between band-power and reaction times in the Theta range for the temporal and parietal lobes. Statistically significant event-related changes (ERC) were observed for the majority of subjects in the frontal lobe for Theta frequencies, Beta waves in the frontal lobe and in all lobes for the Gamma band. Notably, significant ERC was also observed for Theta and Beta frequencies in the temporal and occipital Lobes, Alpha waves in the frontal, parietal and occipital lobes for most participants. A difference in brain activity patterns was observed, depending on the performance in time-restricted tasks.

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Zheng, Yang, Xiaoming Wang, and Xuna Zhao. "Magnetization Transfer and Amide Proton Transfer MRI of Neonatal Brain Development." BioMed Research International 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/3052723.

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Purpose.This study aims to evaluate the process of brain development in neonates using combined amide proton transfer (APT) imaging and conventional magnetization transfer (MT) imaging.Materials and Methods.Case data were reviewed for all patients hospitalized in our institution’s neonatal ward. Patients underwent APT and MT imaging (a single protocol) immediately following the routine MR examination. Single-slice APT/MT axial imaging was performed at the level of the basal ganglia. APT and MT ratio (MTR) measurements were performed in multiple brain regions of interest (ROIs). Data was statistically analyzed in order to assess for significant differences between the different regions of the brain or correlation with patient gestational age.Results.A total of 38 neonates were included in the study, with ages ranging from 27 to 41 weeks’ corrected gestational age. There were statistically significant differences in both APT and MTR measurements between the frontal lobes, basal ganglia, and occipital lobes (APT: frontal lobe versus occipital lobeP=0.031and other groupsP=0.00; MTR: frontal lobe versus occipital lobeP=0.034and other groupsP=0.00). Furthermore, APT and MTR in above brain regions exhibited positive linear correlations with patient gestational age.Conclusions.APT/MT imaging can provide valuable information about the process of the neonatal brain development at the molecular level.

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Dullemeijer, Carla, Peter L. Zock, Ruben Coronel, Hester M. Den Ruijter, Martijn B. Katan, Robert-Jan M. Brummer, Frans J. Kok, Jet Beekman, and Ingeborg A. Brouwer. "Differences in fatty acid composition between cerebral brain lobes in juvenile pigs after fish oil feeding." British Journal of Nutrition 100, no. 4 (October 2008): 794–800. http://dx.doi.org/10.1017/s0007114508943737.

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Very long-chain n-3 PUFA from fish are suggested to play a role in the development of the brain. Fish oil feeding results in higher proportions of n-3 PUFA in the brains of newborn piglets. However, the effect of fish oil on the fatty acid composition of specific cerebral brain lobes in juvenile pigs is largely uninvestigated. This study examined the effect of a fish oil diet on the fatty acid composition of the frontal, parietal, temporal and occipital brain lobes in juvenile pigs (7 weeks old). Pigs were randomly allocated to a semipurified pig diet containing either 4 % (w/w) fish oil (n 19) or 4 % (w/w) high-oleic acid sunflower oil (HOSF diet, n 18) for a period of 8 weeks. The fish oil diet resulted in significantly higher proportions (%) of DHA in the frontal (10·6 (sd1·2)), parietal (10·2 (sd1·5)) and occipital brain lobes (9·9 (sd 1·3)), but not in the temporal lobe (7·7 (sd1·6)), compared with pigs fed the HOSF diet (frontal lobe, 7·5 (sd1·0); parietal lobe, 8·1 (sd 1·3); occipital lobe, 7·3 (sd1·2), temporal lobe, 6·6 (sd1·2). Moreover, the proportion of DHA was significantly lower in the temporal lobe compared with the frontal, parietal and occipital brain lobes in pigs fed a fish oil diet. In conclusion, the brains of juvenile pigs appear to be responsive to dietary fish oil, although the temporal brain lobe is less responsive compared with the other three brain lobes. The functional consequences of these differences are a challenging focus for future investigation.

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MOSCOVITCH, MORRIS, and GORDON WINOCUR. "Frontal Lobes, Memory, and Aging." Annals of the New York Academy of Sciences 769, no. 1 Structure and (December 1995): 119–50. http://dx.doi.org/10.1111/j.1749-6632.1995.tb38135.x.

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O’Muircheartaigh, Jonathan, and Mark P. Richardson. "Epilepsy and the frontal lobes." Cortex 48, no. 2 (February 2012): 144–55. http://dx.doi.org/10.1016/j.cortex.2011.11.012.

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Foroughi, Nasim, Brooke Donnelly, Mark Williams, Sloane Madden, Michael Kohn, Simon Clarke, Perminder Sachdev, Stephen Touyz, and Phillipa Hay. "Neural Response to High and Low Energy Food Images in Anorexia Nervosa." OBM Neurobiology 05, no. 03 (June 1, 2021): 1. http://dx.doi.org/10.21926/obm.neurobiol.2103107.

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To compare neural responses to high and low-energy food images in patients with Anorexia Nervosa (AN) and an age-matched Healthy Control (HC) group. 25 adolescents with AN and 21 HCs completed a diagnostic interview, self-report questionnaires and fMRI, during which they viewed food images evoking responses of disgust, happiness, or fear. Following whole brain analyses, neural responses in six regions of interest were examined in a series of between-group contrasts, across the three emotive categories. Compared to the HCs, people in the AN group showed increased responsivity to high-energy (1) disgust images in temporal lobe, frontal lobe, insula, and cerebellum anterior lobe; (2) fear images in occipital lobe, temporal, and frontal lobes and (3) happy images in frontal lobe, cerebellum anterior lobe, sub-lobar, and cuneus. More activity was observed in response to low-energy (1) disgust food images in the temporal lobe, frontal lobe, insula, cerebellum anterior and posterior lobes, parietal lobe, occipital lobe, and limbic lobe; (2) and happy food images in frontal lobes. Few correlations were found with levels of eating disorder symptoms. The findings highlight the emotional impact of diverse high and low-energy foods for people with AN. People without AN may have a better capacity to filter salient from non-salient information relating to the current task when viewing high energy foods. In summary, for those with AN, it would seem their ability to efficiently ‘sort-out’ information (especially information pertaining to disorder-relevant stimuli such as food images) to complete the task at hand, may be diminished.

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GREENWOOD, PAMELA M. "The frontal aging hypothesis evaluated." Journal of the International Neuropsychological Society 6, no. 6 (September 2000): 705–26. http://dx.doi.org/10.1017/s1355617700666092.

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That the human frontal lobes are particularly vulnerable to age-related deterioration has been frequently invoked as an explanation of functional decline in aging. This “frontal aging hypothesis” is evaluated in this review by examining evidence of selectively reduced frontal lobe function in aging. The frontal aging hypothesis predicts that functions largely dependent on frontal regions would decline in aging, while functions largely independent of frontal lobes would remain relatively spared. The hypothesis further predicts that age-related brain change would selectively impact frontal regions. The literatures on working memory, visuospatial attention, face recognition, and implicit memory were reviewed as exemplars of functions dependent on prefrontal, parietal, temporal and occipitotemporal cortices, respectively, with a view to establishing mediating structures and effects of aging. Age sensitivity was seen both in functions dependent on frontal integrity as well as in functions apparently independent of frontal integrity. Further, although prefrontal areas exhibit age-related decreases in regional volume, blood flow and metabolism, nonfrontal cortical regions undergo similar declines. It is concluded that while the frontal lobes are subject to age-related changes reflected in both behavior and pathology, there is only weak and conflicting evidence that frontal regions are selectively and differentially affected by aging. It is argued that a network-based theory of cognitive aging has advantages over the localizationist approach inherent in the frontal aging hypothesis. (JINS, 2000, 6, 705–726.)

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Sui, Haijing, Juan Yang, Honggang Xiang, and Chenggong Yan. "Combining ADC values in DWI with rCBF values in arterial spin labeling (ASL) for the diagnosis of mild cognitive impairment (MCI)." Medicine 102, no. 37 (September 15, 2023): e34979. http://dx.doi.org/10.1097/md.0000000000034979.

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We aimed to investigate the role of combined apparent diffusion coefficient (ADC) values and relative cerebral blood flow (rCBF) values in the diagnosis of mild cognitive impairment (MCI) patients. The present prospective research enrolled 156 MCI patients and 58 healthy elderly people who came to our hospital from January 2021 to February 2023. T1W, T2W, diffusion-weighted imaging, and arterial spin labeling sequences were performed on all subjects, and ADC values and rCBF values were measured at the workstation. Clinical and demographic data of all patients were collected while mini-mental state examination (MMSE) and Montreal cognitive assessment (MoCA) scores were used to assess patients’ cognitive abilities. The MCI group had significantly lower rCBF values in the left frontal lobe, left occipital lobe, right frontal lobe, and right occipital lobe than the HC group. The ADC values in the left frontal lobe as well as the right frontal lobe were remarkably elevated in the MCI group than in the HC group. MoCA and MMSE scores were positively correlated with rCBF values in the left frontal, right frontal, left occipital, and right occipital lobes and negatively correlated with ADC values in the left and right frontal lobes. Combined ADC values and rCBF values from the left frontal lobe for the diagnosis of MCI had a higher sensitivity and specificity with the AUC was 0.877, sensitivity 81.0%, specificity 82.7%. Additionally, pressure fasting plasma glucose, ADC of the left frontal lobe, right frontal lobe, rCBF of left frontal lobe and rCBF of left frontal lobe were the risk factors of patients with MCI. In summary, our results indicated that the ADC values and rCBF values were changed in MCI group compared to HC group and correlated with MMSE and MoCA scores.

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Buchabaum, M. S. "Frontal Lobes, Basal Ganglia, Temporal Lobes--Three Sites for Schizophrenia?" Schizophrenia Bulletin 16, no. 3 (January 1, 1990): 377–78. http://dx.doi.org/10.1093/schbul/16.3.377.

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Kopp, Bruno, Nina Rösser, Sandra Tabeling, Hans Jörg Stürenburg, Bianca de Haan, Hans-Otto Karnath, and Karl Wessel. "Errors on the Trail Making Test Are Associated with Right Hemispheric Frontal Lobe Damage in Stroke Patients." Behavioural Neurology 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/309235.

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Measures of performance on theTrail Making Test (TMT)are among the most popular neuropsychological assessment techniques. Completion time onTMT-Ais considered to provide a measure of processing speed, whereas completion time onTMT-Bis considered to constitute a behavioral measure of the ability to shift between cognitive sets (cognitive flexibility), commonly attributed to the frontal lobes. However, empirical evidence linking performance on theTMT-Bto localized frontal lesions is mostly lacking. Here, we examined the association of frontal lesions following stroke withTMT-Bperformance measures (i.e., completion time and completion accuracy measures) using voxel-based lesion-behavior mapping, with a focus on right hemispheric frontal lobe lesions. Our results suggest that the number of errors, but not completion time on theTMT-B, is associated with right hemispheric frontal lesions. This finding contradicts common clinical practice—the use of completion time on theTMT-Bto measure cognitive flexibility, and it underscores the need for additional research on the association between cognitive flexibility and the frontal lobes. Further work in a larger sample, including left frontal lobe damage and with more power to detect effects of right posterior brain injury, is necessary to determine whether our observation is specific for right frontal lesions.

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Dubois, Bruno, and Richard Levy. "Cognition, behavior and the frontal lobes." International Psychogeriatrics 16, no. 4 (December 2004): 379–87. http://dx.doi.org/10.1017/s104161020400081x.

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Our knowledge of how the brain functions has markedly improved in recent years, but this improvement has largely been constrained to simpler levels of processing such as those involved in sensory or motor systems. In contrast, the neural bases of higher functions such as consciousness, will, long-term planning, complex problem- solving, etc., are still under investigation, although everyone agrees that the frontal lobes (FL) play an important role in such processes. The importance of understanding these neural bases of higher functions becomes even more evident in the study of aging, since a decrease of frontal lobe perfusion is reported during aging, and because this age-related frontal lobe dysfunction has been proposed to explain part of the cognitive disorders (attention disorders, decreased mental flexibility and abstraction) and behavioral changes (mainly apathy or indifference) associated with aging.

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Vasilyev, Sergey, Dmitry Bulgin, Svetlana Borutskaya, Ilya Chichaev, and Sergey Kartashov. "Endocranium of the Sungir Man (Sungir 1). Preliminary Results of the Study by Means of Computed Tomography." Stratum plus. Archaeology and Cultural Anthropology, no. 1 (February 27, 2022): 83–88. http://dx.doi.org/10.55086/sp2218388.

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The article presents the first results of the study of Sungir 1 endocranium by means of computed tomography. To obtain a 3D model and determine the volume of the individual’s brain, a specialized DICOM viewer was used. On the endocranium, a number of grooves and convolutions were described, as well as the topography of the middle meningeal artery. Clearly seen is the reflection of the division of the telencephalon into frontal, parietal, temporal and occipital lobes. The lateral groove separating the temporal lobe from the frontal and parietal lobes is clearly visible, too. Some development of the occipital lobes of the cerebral cortex, including the visual associative zone, is noted.

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McGilchrist, Iain, Laura H. Goldstein, Danitza Jadresic, and Peter Fenwick. "Thalamo-frontal Psychosis." British Journal of Psychiatry 163, no. 1 (July 1993): 113–15. http://dx.doi.org/10.1192/bjp.163.1.113.

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A 43-year-old man presented with an 18-month history of acute-onset cyclical behavioural change affecting mood, appetite, sleep, and energy levels. This had followed an initial episode of transient drowsiness which lasted 24 hours. On examination, there was soma evidence of visual memory and frontal lobe deficits. A brain CT scan showed bilateral thalamic infarcts and a brain SPECT scan showed bilateral hypoperfusion of the frontal lobes. To our knowledge, this is the first reported case of thalamic infarction associated with acute-onset cyclical affective psychosis with clinical and neurophysiological features of frontal lobe syndrome. The case also highlights the possible role of thalamofrontal circuits in the pathogenesis of the Kleine-Levin syndrome.British Journal of Psychiatry (1993), 163, 113–115

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Benjamin, Sheldon. "The Frontal Lobes and Neuropsychiatric Illness." Journal of Clinical Psychiatry 63, no. 7 (July 15, 2002): 598. http://dx.doi.org/10.4088/jcp.v63n0711b.

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Volz, Kirsten G., Ricarda I. Schubotz, and D. Yves von Cramon. "Decision-making and the frontal lobes." Current Opinion in Neurology 19, no. 4 (August 2006): 401–6. http://dx.doi.org/10.1097/01.wco.0000236621.83872.71.

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Warkentin, Siegbert, and Ulla Passant. "Functional Activation of the Frontal Lobes." Dementia and Geriatric Cognitive Disorders 4, no. 3-4 (1993): 188–91. http://dx.doi.org/10.1159/000107322.

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Reverberi, Carlo, Antonio Lavaroni, Gian Luigi Gigli, Miran Skrap, and Tim Shallice. "Inductive Inferences and the Frontal Lobes." Cortex 38, no. 5 (January 2002): 899–902. http://dx.doi.org/10.1016/s0010-9452(08)70066-2.

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Anderson, Vicki. "What's New With the Frontal Lobes?" Journal of the International Neuropsychological Society 14, no. 1 (December 14, 2007): 177–78. http://dx.doi.org/10.1017/s1355617708080247.

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The Human Frontal Lobes: Functions and Disorders (Second Edition). 2007. Bruce L. Miller & Jeffrey L. Cummings (Eds.). New York: The Guilford Press, 666 pp., $95.00 (HB)Miller and Cummings published their original text, The Human Frontal Lobes: Functions and Disorders, in 1999. At that time, their work was quite unique and provided a valuable reference for both health professionals and researchers in the emerging field of the frontal lobes. The years since then have seen an increasing focus on these fascinating brain structures across a range of disciplines including neurosciences, neurology, neuropsychology and psychiatry. The importance of the frontal structures for both cognition and emotion is firmly established and the complexity of these associations continues to challenge those working in these fields. As Miller and Cummings note, due to the major advances that have occurred since they first published their work, their second edition represents not only an update but also an introduction to a range of new issues. In particular, this second edition emphasizes advances in neurosciences and neuroimaging with a substantial amount of new material presented in these areas. In addition, the increasing interest in the role of the frontal lobes in social and emotional function is also acknowledged and discussed.

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Levy, R. "Functional organization of the frontal lobes." Annals of Physical and Rehabilitation Medicine 56 (October 2013): e340. http://dx.doi.org/10.1016/j.rehab.2013.07.881.

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Miller, L. "The Subcortex, Frontal Lobes, and Psychosis." Schizophrenia Bulletin 12, no. 3 (January 1, 1986): 340–41. http://dx.doi.org/10.1093/schbul/12.3.340.

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Schiller, Francis. "The Mystique of the Frontal Lobes." Gesnerus 42, no. 3-4 (November 19, 1985): 415–24. http://dx.doi.org/10.1163/22977953-0420304018.

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Goldstein, Laura H. "The frontal lobes and voluntary action." Behaviour Research and Therapy 34, no. 7 (July 1996): 602. http://dx.doi.org/10.1016/0005-7967(96)87642-x.

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Shulman, Melanie B. "The Frontal Lobes, Epilepsy, and Behavior." Epilepsy & Behavior 1, no. 6 (December 2000): 384–95. http://dx.doi.org/10.1006/ebeh.2000.0127.

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Jamil, Muhammad, Numair Ahmed Siddiqui, Nisar Ahmed, Muhammad Usman, Muhammad Umar, Hamad ur Rahim, and Qazi Sohail Imran. "Facies Analysis and Sedimentary Architecture of Hybrid Event Beds in Submarine Lobes: Insights from the Crocker Fan, NW Borneo, Malaysia." Journal of Marine Science and Engineering 9, no. 10 (October 15, 2021): 1133. http://dx.doi.org/10.3390/jmse9101133.

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Hybrid event beds represent the combined effect of multiple geological processes, which result in complex depositional geometries and distinct facies distribution in marine environments. Previous work on hybrid event beds highlights the classification, origin, and types of hybrid facies. However, in the present study, we discuss the development of hybrid event beds in submarine lobes with an emphasis on the analysis of proximal to distal, frontal to lateral relationships and evolution during lobe progradation. Detailed geological fieldwork was carried out in the classical deep-marine Late Paleogene Crocker Fan to understand the relationship between the character of hybrid bed facies and lobe architecture. The results indicate that hybrid facies of massive or structureless sandstone with mud clasts, clean to muddy sand, and chaotic muddy sand with oversized sand patch alternations (H1–H3) are well developed in proximal to medial lobes, while distal lobes mainly contain parallel to cross-laminated clean to muddy hybrid facies (H3–H5). Furthermore, lateral lobes have less vertical thickness of hybrid beds than frontal lobes. The development of hybrid beds takes place in the lower part of the thickening upward sequence of lobe progradation, while lobe retrogradation contains hybrid facies intervals in the upper part of stratigraphy. Hence, the development of hybrid beds in submarine lobe systems has a significant impact on the characterization of heterogeneities in deep-marine petroleum reservoirs at sub-seismic levels.

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Igliori, Glauco C., and Benito P. Damasceno. "Theory of mind and the frontal lobes." Arquivos de Neuro-Psiquiatria 64, no. 2a (June 2006): 202–6. http://dx.doi.org/10.1590/s0004-282x2006000200006.

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BACKGROUND: Theory of mind (ToM) is the ability to attribute mental states to other individuals. Its cerebral organization is not enough established, even though the literature suggests the relevant role of the frontal lobes. OBEJECTIVE: To evaluate frontal lobe patients and controls in ToM tests. METHOD:We studied 20 patients with lesions limited to the frontal lobes (as shown by CT or MRI), and 10 normal control subjects by means of ToM tests (recognizing himself in mirrors, false belief, first and second order ToM tasks), as well as tests of other cognitive functions (counter-proofs). RESULTS: Patients and controls performed similarly in ToM tests. There was significant difference between frontal subgroups (left, right, bifrontal) in the double-bluff task (second order ToM) (p=0.021), without relation to verbal fluency (p=0.302) or delayed recall ability (p=0.159). The only two patients with deficits in ToM tasks had impairment of social behavior. CONCLUSION: Frontal lesions do not necessarily implicate in ToM deficits, which may occur when such lesions are associated to disturbance of social behavior.

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HAMAKAWA, H., T. KATO, T. SHIOIRI, T. INUBUSHI, and N. KATO. "Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder." Psychological Medicine 29, no. 3 (May 1999): 639–44. http://dx.doi.org/10.1017/s0033291799008442.

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Background. Using 31P and 1H magnetic resonance spectroscopy (MRS) we previously reported that phosphocreatine was decreased in the left frontal lobe and choline-containing compounds were increased in the basal ganglia in the depressive state in patients with bipolar disorder. We applied quantitative 1H-MRS for further characterization of biochemical alteration in the frontal lobes of bipolar patients.Methods. Twenty-three bipolar patients and 20 normal controls were examined by 1H-MRS with a 1.5T MR system. All patients were examined in the euthymic state, and eight patients were also examined in the depressive state. Volumes of interest of 2·5×2·5×2·5 cm were selected in the left and right frontal lobes. Absolute concentrations of N-acetyl-l-aspartate, creatine plus phosphocreatine, and choline-containing compounds were calculated from each metabolite peak.Results. Creatine concentration in the left frontal lobe in bipolar patients in the depressive state was significantly lower than that in the euthymic state. Creatine concentration in the right frontal lobe in the male patients was significantly higher than that in the female patients and a similar trend was also found in the control subjects.Conclusions. We found a state-dependent change of creatine metabolism in the left frontal lobe of bipolar patients. The present results are compatible with our previous report of decreased phosphocreatine measured by 31P-MRS in the left frontal lobe in bipolar disorder. We also found an effect of gender on the creatine concentration. There may be a gender difference in creatine transport function into the brain.

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Festini, Sara B., and Benjamin Katz. "A Frontal Account of False Alarms." Journal of Cognitive Neuroscience 33, no. 9 (August 1, 2021): 1657–78. http://dx.doi.org/10.1162/jocn_a_01683.

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Abstract Prior research has demonstrated that the frontal lobes play a critical role in the top–down control of behavior, and damage to the frontal cortex impairs performance on tasks that require executive control [Burgess, P. W., & Stuss, D. T. Fifty years of prefrontal cortex research: Impact on assessment. Journal of the International Neuropsychological Society, 23, 755–767, 2017; Stuss, D. T., & Levine, B. Adult clinical neuropsychology: Lessons from studies of the frontal lobes. Annual Review of Psychology, 53, 401–433, 2002]. Across executive functioning tasks, performance deficits are often quantified as the number of false alarms per total number of nontarget trials. However, most studies of frontal lobe function focus on individual task performance and do not discuss commonalities of errors committed across different tasks. Here, we describe a neurocognitive account that explores the link between deficient frontal lobe function and increased false alarms across an array of experimental tasks from a variety of task domains. We review evidence for heightened false alarms following frontal deficits in episodic long-term memory tests, working memory tasks (e.g., n-back), attentional tasks (e.g., continuous performance tasks), interference control tasks (e.g., recent probes), and inhibitory control tasks (e.g., go/no-go). We examine this relationship via neuroimaging studies, lesion studies, and across age groups and pathologies that impact the pFC, and we propose 11 issues in cognitive processing that can result in false alarms. In our review, some overlapping neural regions were implicated in the regulation of false alarms. Ultimately, however, we find evidence for the fractionation and localization of certain frontal processes related to the commission of specific types of false alarms. We outline avenues for additional research that will enable further delineation of the fractionation of the frontal lobes' regulation of false alarms.

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Post, Andrew, T. Blaine Hoshizaki, Michael D. Gilchrist, Susan Brien, Michael D. Cusimano, and Shawn Marshall. "The influence of dynamic response and brain deformation metrics on the occurrence of subdural hematoma in different regions of the brain." Journal of Neurosurgery 120, no. 2 (February 2014): 453–61. http://dx.doi.org/10.3171/2013.10.jns131101.

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Object The purpose of this study was to examine how the dynamic response and brain deformation of the head and brain—representing a series of injury reconstructions of which subdural hematoma (SDH) was the outcome—influence the location of the lesion in the lobes of the brain. Methods Sixteen cases of falls in which SDH was the outcome were reconstructed using a monorail drop rig and Hybrid III headform. The location of the SDH in 1 of the 4 lobes of the brain (frontal, parietal, temporal, and occipital) was confirmed by CT/MR scan examined by a neurosurgeon. Results The results indicated that there were minimal differences between locations of the SDH for linear acceleration. The peak resultant rotational acceleration and x-axis component were larger for the parietal lobe than for other lobes. There were also some differences between the parietal lobe and the other lobes in the z-axis component. Maximum principal strain, von Mises stress, shear strain, and product of strain and strain rate all had differences in magnitude depending on the lobe in which SDH was present. The parietal lobe consistently had the largest-magnitude response, followed by the frontal lobe and the occipital lobe. Conclusions The results indicated that there are differences in magnitude for rotational acceleration and brain deformation metrics that may identify the location of SDH in the brain.

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McDonald, Skye. "The Social, Emotional and Cultural Life of the Orbitofrontal Cortex." Brain Impairment 8, no. 1 (May 1, 2007): 41–51. http://dx.doi.org/10.1375/brim.8.1.41.

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AbstractFormal assessment of the impact of frontal-lobe impairment on social and interpersonal function has been somewhat neglected relative to interest in documenting executive impairment on nonsocial tasks. Despite this, experimental evidence is accruing that attests to the role of the orbitomedial frontal lobes, the amygdala and related structures in the appraisal and interpretation of socially relevant stimuli. In this address the evidence regarding the frontal lobes and social cognition, that is, social information processing is reviewed. At least 3 different constructs have been proposed that appear to be mediated by cerebral systems encompassing the orbitomedial frontal cortex: (1) social schema or social knowledge networks that guide judgments and behavioural responses, (2) emotional processing, including both the ability to recognise different affective states in others and the ability to experience affective (somatic) responses to emotionally important environmental stimuli, and (3) theory of mind – the ability to conceptualise what others are thinking and feeling. On the basis of this recent experimental work it is argued that a variety of assessment techniques are becoming available that are both practical and potentially sensitive to psychosocial changes after frontal lobe damage.

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Wolfla, Christopher E., Thomas G. Luerssen, and Robin M. Bowman. "Regional brain tissue pressure gradients created by expanding extradural temporal mass lesion." Journal of Neurosurgery 86, no. 3 (March 1997): 505–10. http://dx.doi.org/10.3171/jns.1997.86.3.0505.

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✓ A porcine model of regional intracranial pressure was used to compare regional brain tissue pressure (RBTP) changes during expansion of an extradural temporal mass lesion. Measurements of RBTP were obtained by placing fiberoptic intraparenchymal pressure monitors in the right and left frontal lobes (RF and LF), right and left temporal lobes (RT and LT), midbrain (MB), and cerebellum (CB). During expansion of the right temporal mass, significant RBTP gradients developed in a reproducible pattern: RT > LF = LT > RF > MB > CB. These gradients appeared early, widened as the volume of the mass increased, and persisted for the entire duration of the experiment. The study indicates that RBTP gradients develop in the presence of an extradural temporal mass lesion. The highest RBTP was recorded in the ipsilateral temporal lobe, whereas the next highest was recorded in the contralateral frontal lobe. The RBTP that was measured in either frontal lobe underestimated the temporal RBTP. These results indicated that if a frontal intraparenchymal pressure monitor is used in a patient with temporal lobe pathology, the monitor should be placed on the contralateral side and a lower threshold for therapy of increased intracranial pressure should be adopted. Furthermore, this study provides further evidence that reliance on a single frontal intraparenchymal pressure monitor may not detect all areas of elevated RBTP.

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Białaszek, Wojciech, Bartłomiej Swebodziński, and Paweł Ostaszewski. "Intertemporal Decision Making After Brain Injury: Amount-Dependent Steeper Discounting after Frontal Cortex Damage." Polish Psychological Bulletin 48, no. 4 (December 20, 2017): 456–63. http://dx.doi.org/10.1515/ppb-2017-0052.

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Abstract Traumatic brain injuries to the frontal lobes are associated with many maladaptive forms of behavior. We investigated the association between brain damage and impulsivity, as measured by the rate of delay discounting (i.e., the extent to which future outcomes are devalued in time). The main aim of this study was to test the hypothesis of steeper discounting of different amounts in a group of patients with frontal lobe damage. We used a delay discounting task in the form of a structured interview. A total of 117 participants were divided into five groups: three neurological groups and two groups without brain damage. Our analyses showed that patients with focal damage to the frontal lobes demonstrated steeper delay discounting than other participants. Other clinical groups demonstrated similar discounting rates. The data pattern related to the magnitude effect on the group level suggested that the magnitude effect is absent in the group of patients with damage to the frontal lobes; however, results were less consistent on an individual level. Amount-dependent discounting was observed in only two groups, the healthy control group and the neurological group with other cortical areas damaged.

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Kashirskiy, D. V., and O. V. Staroseltseva. "Features of Criminal Behavior of the Accused of the Particularly Serious Crime with Violations of Programming, Regulation and Control Functions of Mental Activity (Part 2)." Psychology and Law 14, no. 1 (April 4, 2024): 183–96. http://dx.doi.org/10.17759/psylaw.2024140112.

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<p style="text-align: justify;">The purpose of our study was the features of criminal behavior of the accused in the commission of particularly serious crimes in the context of the formation functions of programming and control. The sample consisted of 59 men aged 18—60 years, of those accused of committing particularly serious crimes aimed at a forensic psychiatric examination, the average age was 33.7 years. The methods of neuropsychological examination and psychological analysis of criminal cases were used. Syndrome of defeat of the basal divisions of the frontal lobes, prefrontal syndrome, syndrome of defeat of the medial divisions of the frontal lobes, Postfrontal (premotor) syndrome is most often seen among persons accused of particularly serious crimes. The criminal behavior of the accused in the Commission of particularly serious crimes was characterized by uncritical damage to the basal parts of the frontal lobes. The impulsivity is the main characteristic of the criminal behavior of the accused in especially serious crimes with the defeat of the prefrontal frontal lobe (prefrontal syndrome). Subjects with the defeat of the kinetic (dynamic) factor differed greater rigidity of criminal behavior. The behavior of those accused of committing particularly serious crimes was passive (energy-saving) in violation of the energy factor in the case of damage to the medial parts of the frontal lobes. The obtained results can be used to solve the issues of drawing a portrait of an unknown criminal, as well as in the course of correctional work with persons prone to repeat illegal behavior.</p>

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Kashirskiy, D. V., and O. V. Staroseltseva. "Features of Criminal Behavior of the Accused of the Particularly Serious Crime with Violations of Programming, Regulation and Control Functions of Mental Activity (Part 1)." Psychology and Law 13, no. 4 (December 29, 2023): 53–69. http://dx.doi.org/10.17759/psylaw.2023130405.

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<p style="text-align: justify;">The purpose of our study was the features of criminal behavior of the accused in the commission of particularly serious crimes in the context of the formation functions of programming and control. The sample consisted of 59 men aged 18—60 years, of those accused of committing particularly serious crimes aimed at a forensic psychiatric examination, the average age was 33.7 years. The methods of neuropsychological examination and psychological analysis of criminal cases were used. Syndrome of defeat of the basal divisions of the frontal lobes, prefrontal syndrome, syndrome of defeat of the medial divisions of the frontal lobes, Postfrontal (premotor) syndrome is most often seen among persons accused of particularly serious crimes. The criminal behavior of the accused in the Commission of particularly serious crimes was characterized by uncritical damage to the basal parts of the frontal lobes. The impulsivity is the main characteristic of the criminal behavior of the accused in especially serious crimes with the defeat of the prefrontal frontal lobe (prefrontal syndrome). Subjects with the defeat of the kinetic (dynamic) factor differed greater rigidity of criminal behavior. The behavior of those accused of committing particularly serious crimes was passive (energy-saving) in violation of the energy factor in the case of damage to the medial parts of the frontal lobes. The obtained results can be used to solve the issues of drawing a portrait of an unknown criminal, as well as in the course of correctional work with persons prone to repeat illegal behavior.</p>

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Journal articles on the topic 'Frontal lobes'

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