Relevant bibliographies by topics / Friedel-Crafts acylation

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Academic literature on the topic 'Friedel-Crafts acylation'

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Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Friedel-Crafts acylation"

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Đud, Mateja, Anamarija Briš, Iva Jušinski, Davor Gracin, and Davor Margetić. "Mechanochemical Friedel–Crafts acylations." Beilstein Journal of Organic Chemistry 15 (June 17, 2019): 1313–20. http://dx.doi.org/10.3762/bjoc.15.130.

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Friedel–Crafts (FC) acylation reactions were exploited in the preparation of ketone-functionalized aromatics. Environmentally more friendly, solvent-free mechanochemical reaction conditions of this industrially important reaction were developed. Reaction parameters such as FC catalyst, time, ratio of reagents and milling support were studied to establish the optimal reaction conditions. The scope of the reaction was explored by employment of different aromatic hydrocarbons in conjunction with anhydrides and acylation reagents. It was shown that certain FC-reactive aromatics could be effectively functionalized by FC acylations carried out under ball-milling conditions without the presence of a solvent. The reaction mechanism was studied by in situ Raman and ex situ IR spectroscopy.
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Tran, Phuong Hoang, Thanh Duy Anh Nguyen, and Thach Ngoc Le. "Friedel-crafts acylation of aromatic compounds using Triflat bismuth." Science and Technology Development Journal 17, no. 2 (June 30, 2014): 10–14. http://dx.doi.org/10.32508/stdj.v17i2.1310.

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Friedel-Crafts acylation of aromatic compounds with acetic anhydride as acylating reagent was investigated in the presence of Lewis acid. Bismuth trifluoromethanesulfonate was found to be efficient catalyst for Friedel-Crafts acetylation under mild conditions. Bismuth triflate is safe-to-handle, simple and clean work-up, good yield and short reaction time
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Toma, Štefan, and Marta Sališová. "Acylation of ω-phenylalkanoylferrocenes by cinnamoyl and phenylpropiolyl chlorides." Collection of Czechoslovak Chemical Communications 52, no. 6 (1987): 1520–26. http://dx.doi.org/10.1135/cccc19871520.

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In Friedel-Crafts acylation of ω-phenylalkanoylferrocenes, the site of electrophilic attack depends on the reagent used. The acylation with cinnamoyl chloride yields preferentially the products of substitution of the unsubstituted cyclopentadienyl ring of ferrocene. The acylation with phenylpropionyl chloride affords the products of acylation of the benzene ring of the starting compound. The different behaviour of both acylating agents is discussed.
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Esteban, Gema, Rocío Rincón, Aurelio G. Csákÿ, and Joaquín Plumet. "A Convenient Synthesis of the Central Core of Helioporins, seco-Pseudopterosins and Pseudopterosins via BCA-Annulation Sequence." Natural Product Communications 3, no. 4 (April 2008): 1934578X0800300. http://dx.doi.org/10.1177/1934578x0800300405.

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A convenient synthesis of the central core of helioporins, seco-pseudopterosins and pseudopterosins in racemic form is reported, using a Suzuki coupling (A-ring formation)-Friedel-Crafts acylation sequence, followed by synthetic elaboration of the resulting tetralone derivative. Key steps of the method are a totally diastereoselective cuprate conjugate addition and a final, spontaneous Friedel-Crafts acylation.
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Metivier, Pascal. "ChemInform Abstract: Friedel-Crafts Acylation." ChemInform 33, no. 41 (May 19, 2010): no. http://dx.doi.org/10.1002/chin.200241266.

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Chua, Chun Kiang, and Martin Pumera. "Friedel-Crafts Acylation on Graphene." Chemistry - An Asian Journal 7, no. 5 (March 13, 2012): 1009–12. http://dx.doi.org/10.1002/asia.201200096.

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Raja, Erum K., Daniel J. DeSchepper, Sten O. Nilsson Lill, and Douglas A. Klumpp. "Friedel–Crafts Acylation with Amides." Journal of Organic Chemistry 77, no. 13 (June 21, 2012): 5788–93. http://dx.doi.org/10.1021/jo300922p.

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Lan, Kun, Shao Fen, and Zixing Shan. "Synthesis of Aromatic Cycloketones via Intramolecular Friedel - Crafts Acylation Catalyzed by Heteropoly Acids." Australian Journal of Chemistry 60, no. 1 (2007): 80. http://dx.doi.org/10.1071/ch06277.

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Under liquid-phase conditions, the intramolecular Friedel–Crafts acylation of aryl benzoic acids catalyzed by heteropoly acids were investigated for the first time. Several aryl benzoic acids were refluxed and dehydrated in chlorobenzene in the presence of 0.2 equivalents of a heteropoly acid, and anthraquinone, anthrone, and xanthone were obtained in good yield. At the same time, an intermolecular Friedel–Crafts acylation and decarboxylation reaction were observed in this experiment.
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Jadhav, Arvind H., Amutha Chinnappan, Vishwanath Hiremath, and Jeong Gil Seo. "Synthesis and Characterization of AlCl3 Impregnated Molybdenum Oxide as Heterogeneous Nano-Catalyst for the Friedel-Crafts Acylation Reaction in Ambient Condition." Journal of Nanoscience and Nanotechnology 15, no. 10 (October 1, 2015): 8243–50. http://dx.doi.org/10.1166/jnn.2015.11253.

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Aluminum trichloride (AlCl3) impregnated molybdenum oxide heterogeneous nano-catalyst was prepared by using simple impregnation method. The prepared heterogeneous catalyst was characterized by powder X-ray diffraction, FT-IR spectroscopy, solid-state NMR spectroscopy, SEM imaging, and EDX mapping. The catalytic activity of this protocol was evaluated as heterogeneous catalyst for the Friedel-Crafts acylation reaction at room temperature. The impregnated MoO4(AlCl2)2 catalyst showed tremendous catalytic activity in Friedel-Crafts acylation reaction under solvent-free and mild reaction condition. As a result, 84.0% yield of acyl product with 100% consumption of reactants in 18 h reaction time at room temperature was achieved. The effects of different solvents system with MoO4(AlCl2)2 catalyst in acylation reaction was also investigated. By using optimized reaction condition various acylated derivatives were prepared. In addition, the catalyst was separated by simple filtration process after the reaction and reused several times. Therefore, heterogeneous MoO4(AlCl2)2 catalyst was found environmentally benign catalyst, very convenient, high yielding, and clean method for the Friedel-Crafts acylation reaction under solvent-free and ambient reaction condition.
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Tran, Phuong Hoang, Vy Hieu Huynh, Hai Ngoc Tran, and Thach Ngoc Le. "Microwave-assisted intramolecular FriedelCrafts acylation of some aryl aliphatic acids using Gd(OTf)3/ [BMI]BF4 catalytic system." Science and Technology Development Journal 19, no. 2 (June 30, 2016): 64–70. http://dx.doi.org/10.32508/stdj.v19i2.803.

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Intramolecular Friedel–Crafts acylation of aryl acids is a “green” reaction and environmentally benign, generates some valuable intermediated compounds for pharmaceutical uses. In addition, metal triflates under microwave irradiation are efficient catalysts, solving many problems when using traditional Lewis acids. Gd(OTf)3/[BMI]BF4, a good catalyst for the intramolecular Friedel–Crafts acylation under mild condition with high yield, reduced the reaction time and pollution. Furthermore, Gd(OTf)3 in [BMI]BF4 was easily recovered and reused without significant loss of its activity
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Dissertations / Theses on the topic "Friedel-Crafts acylation"

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Jayne, A. J. "Friedel-Crafts acylation reactions catalysed by solids." Thesis, Swansea University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637410.

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The various inorganic solids that may be employed as heterogeneous catalysts in organic reactions are discussed in Chapter 1. In the present climate, heterogeneous catalysts are seen as more environmentally acceptable alternatives to homogeneous Lewis acid type catalysts. Chapter 2 describes the Friedel-Crafts acylation of aromatics. Discussion focuses on both the classical and solid catalysed reactions. The study of a pharmaceutical intermediate is described in Chapter 3. The aims of the work described were to develop an efficient and commercially viable process for the production of 1-(4-methoxyphenyl)-2-phenyl-1-butanone by the acylation of anisole over a suitable heterogeneous catalyst. In Part A of Chapter 4, the acetylation of a range of 1,2-disubstituted aromatics over solids is discussed. Part B describes the use of different anhydrides in the acylation of 2,3-dihydrobenzofuran over a number of solids to elucidate the generality of the reaction. Investigations show the influence of the solid catalyst and the effective recovery and regeneration of a zeolite catalyst. Finally, the acylation of 2,3-dihydrobenzofuran with ethyl oxalyl chloride over heterogeneous catalysts is described in Chapter 5. The reaction proved difficult with close consideration given to the reasoning behind the poor performance of the reaction; a good case in point being the amount of material unaccounted for in certain experiments. Investigations led to the isolation and characterisation of what were considered to be likely by-products of the reaction. Efforts were made to reduce the likelihood of such by-products being formed and with further attention, a yield of 73% of the corresponding para acylated product was formed in the presence of zeolite Hβ after 7 days. Having speculated that the difficulties encountered during the study of this reaction may lie with the nature of the acylating agent, the use of mixed anhydrides based on ethyl oxalyl chloride as potential acylating agents was investigated.
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Kaur, Jaspalne. "Friedel-Crafts acylation catalysed by heteropoly acids." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272747.

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Aribert, Nicolas. "Acylation hétérogène de Friedel-Crafts en milieu CO2 supercritique." Phd thesis, Toulouse, INPT, 2009. http://oatao.univ-toulouse.fr/16222/1/aribert.pdf.

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L’acylation de Friedel-Crafts est parmi les réactions les plus fondamentales et les plus utiles pour former des cétones aromatiques. Bien que la mise en oeuvre de ces réactions soit habituellement pénalisante en termes de sous produits formés, de rendement atomique et de quantité de catalyseur utilisée, cette voie est encore largement utilisée dans l’industrie de la chimie fine. Ces dernières années, la prise de conscience de l’impact des activités industrielles sur l’environnement a mené les chimistes à travailler sur de nouvelles voies, moins dangereuses et plus respectueuses de l’environnement.Nous avons considéré ici l’acylation d’un dérivé du benzofurane par un chlorure d’acyle, correspondant à une étape intermédiaire pour la fabrication d’un principe actif pharmaceutique. Dans cette étude, la première proposition a consisté à remplacer les catalyseurs classiques (FeCl3 ou AlCl3) par des catalyseurs solides réutilisables. Dans ce travail, plusieurs catalyseurs (zéolites, résines échangeuses d’ions...) ont d’abord été testés dans des conditions « conventionnelles » , c’est-à-dire en utilisant un solvant organique, afin de déterminer le plus performant, en termes de réactivité, de durée de vie et de réutilisabilité. Une zéolite Y s’est avéré la plus adaptée. Cependant, l’utilisation d’un solvant organique (ici le 1,2-dichlorobenzène) reste discutable et l’utilisation du CO2 supercritique comme solvant a donc été envisagée. Pour cela, nous avons imaginé et dimensionné un réacteur tubulaire à lit fixe de catalyseur fonctionnant sous pression et en continu. Les résultats présentés montrent la faisabilité d’un tel procédé et pose les jalons pour arriver à une ou des solutions pour une meilleure mise en oeuvre industrielle des réactions de Friedel-Crafts.
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Gardner, June Ann. "Friedel-Crafts acylation reactions using heterogeneous catalysts stimulated by microwave radiation." Thesis, University of Central Lancashire, 2004. http://clok.uclan.ac.uk/20208/.

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Ion exchanged zeolites, ion exchanged clays, sulphated zirconia and silica supported phosphotungstic acid were prepared. Characterisation of the catalysts using pyridine adsorption revealed the catalysts contained both Brønsted and Lewis acid sites. When the catalytic activities for the acylation of toluene and anisole were studied there was found to be a correlation between the Brønsted acidity and the catalytic activity. The reactivity of the catalysts is dependant upon both the concentration and the chain length of the carboxylic acid. An optimum chain length being in the range Cm-C12. An aromatic:carboxylic molar ratio of 30: I was demonstrated to be preferable to either 300:1 or 3:1. The activation energies for the acylation of toluene were determined to be in the range 165-359 ki mol' and those for anisole 67-196 kJ mor 1 . Microwave experiments were performed in both batch and flow reactors. Under both reactor configurations microwave stimulation gave consistent increases in catalyst activity. Attempts were made to correlate this with the material dielectric properties, unfortunately, no correlation was found. Under the high E-field conditions Of the single mode (flow reactor) only the zeolites proved to be sufficiently robust as to provide any meaningful data. These catalysts displayed an increased selectivity to the ortho-isomer which was maximised when hexanoic acid was used as the acylating agent. The selectivity to the ortho-isomer increased with increasing microwave power.
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Sawazaki, David Tatsuo Atique. "Funcionalização de grafite em condições de Friedel-Crafts." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-28112013-151124/.

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Neste trabalho foi realizada a funcionalização de grafite sem prévio tratamento em condições de Fridel-Crafts. Considerando que a grafite não possui hidrogênio em sua estrutura, não se observa uma reação de substituição eletrofílica. Por outro lado, o trabalho mostra o papel da umidade presente no grafite na reação de funcionalização. Dessa forma, foi proposto um mecanismo para a reação com a participação da água adsorvida na grafite estabilizando o carbocátion formado. O grafite funcionalizado obtido na reação foi utilizado como material eletródico. Para a reação de funcionalização, quatro moléculas foram utilizadas: ácido ferrocenomonocarboxílico, cloreto de 4-nitrobenzoíla, cloreto de 3,5-dinitrobenzoíla e ácido 3,4-dinitrobenzóico. Para o estudo das condições ótimas da reação, utilizou-se diferentes potências de radiação no reator de micro-ondas, sendo que a extensão da funcionalização mostrou-se sensível à variação deste parâmetro. Para a caracterização dos materiais, utilizou-se voltametria cíclica e análise térmica (TG e DTA). Resultados de infravermelho e Ramam são apresentados no Apêndice A. Os resultados eletroquímicos mostraram que os materiais funcionalizados em maiores potências apresentaram maior corrente Faradaica, mas ao mesmo tempo, o material obtido foi mais resistivo. A diferença de potencial relacionada ao processo redox do ferroceno aumentou conforme a extensão da funcionalização, uma vez que um sobrepotencial é necessário devido ao fluxo iônico (para a manutenção da eletroneutralidade) relativo ao número de espécies envolvidas. Os resultados eletroquímicos também indicaram que a funcionalização do grafite com os nitro compostos foi baixa. A análise térmica evidenciou que a reação de funcionalização do grafite com o ferroceno resultou em materiais com 15% a 20% (m/m) de material ligado ao grafite. Os materiais funcionalizados a maiores potências apresentaram maior massa ligada ao grafite. A funcionalização com os nitro compostos resultou em materiais com menos de 3% (m/m) de composto ligado ao grafite. Os resultados das duas técnicas mostraram coerência na análise da extensão da funcionalização. O material funcionalizado com o ácido ferrocenomonocarboxilico foi o que apresentou os melhores resultados e propõe-se uma explicação para tal baseado no mecanismo de reação sugerido. Com o objetivo de melhor elucidar o mecanismo da reação, foram realizadas algumas reações na ausência de alguns reagentes. Por exemplo, quando tenta-se funcionalizar o material sem a presença de cloreto de alumínio ou sem a umidade natural do grafite, a reação não ocorre.
In this work natural graphite functionalization in Fridel-Crafts conditions is performed using a one-step microwave assisted reaction. Since there is no hydrogen in graphite structure, it is not possible to observe electrophilic substitution. On the other hand this work shows the role of the moisture present on graphite in the functionalization reaction under this condition. Therefore, a reaction mechanism with the participation of the water naturally adsorbed on graphite stabilizing the formed carbocation has been suggested. After the reaction, the functionalized graphite was used as electrode material. Four molecules were used to functionalize graphite: Ferrocene monocarboxylic acid, 4-nitrobenzoyl chloride, 3,5-dinitrobenzoyl chloride and 3,4-dinitrobenzoic acid. To study the optimal conditions of the reaction, the microwave radiation power was varied and the extent of the functionalization on graphite was sensitive to this parameter. Two techniques were used to characterize the materials, cyclic voltammetry and thermal analysis (TG and DTA). IR and Raman data are shown in appendix A. Electrochemical results have shown that the materials functionalized at higher microwave radiation power have higher Faradaic current, but are more resistive. The potential difference between the peaks of the redox process of ferrocene increased with the extent of functionalization. This occurs because an overpotencial is needed to compensate the ionic flux (in order to maintain the electroneutrality) related to the number of species involved. The electrochemical results also indicated that the extent of functionalization of graphite with the nitro compounds was low. The thermal analysis have shown that the functionalization of graphite with ferrocene lead to values between 15% to 20% (m/m) of compound in the material. The materials functionalized at higher microwave radiation power presented higher relative mass in the material. The reaction with the nitro compounds lead to less than 3% (m/m) of compound in the final material. The results of both techniques were coherent about the extent of functionalization. The material functionalized with ferrocene monocarboxylic acid showed the best results, and an explanation for that based on the reaction mechanism is suggested. In order to elucidate the reaction mechanism, some experiments were realized in absent of some reagents. When the reaction were carried out without aluminum chloride or with dried graphite, the reaction has not occurred.
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Drouillard, Joe͏̈lle. "Utilisation de zéolithes dans les réactions de type Friedel-Crafts : acylation et alkylation du thiophène." Poitiers, 1995. http://www.theses.fr/1995POIT2266.

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Les derives du thiophene ont trouve ces dernieres annees de nombreux debouches dans les domaines alimentaires, agrochimique et surtout pharmaceutique. En particulier, la decouverte des proprietes anti-inflammatoires et antalgiques de certains derives aroyles des acides thienylacetiques a initie de nombreuses recherches concernant les derives du thiophene, permettant de mettre a jour l'activite therapeutique d'autres molecules. L'acylation et l'alkylation des composes aromatiques heterocycliques sont traditionnellement realisees par des reactions de type friedel et crafts, par catalyse homogene au moyen d'acides de lewis ou d'acides protoniques forts. L'utilisation de ce type de catalyseur pose des problemes a la fois d'ordre economique et environnemental. L'objectif de ce travail etait d'essayer de les remplacer par des catalyseurs non polluants et regenerables, comme les catalyseurs acides solides, en particulier les zeolithes. Les resultats obtenus en acylation et en alkylation du thiophene montrent que les performances en terme d'activite et de selectivite des zeolithes sont semblables voire superieures a celles acides de lewis. De plus ces catalyseurs sont parfaitement regenerables, et la recuperation des produits est tres facile. Une etude cinetique complete des deux reactions realisee sur une zeolithe y d'acidite moyenne nous a permis de determiner les mecanismes reactionnels. Nous avons ensuite examine l'influence de la nature du catalyseur sur son activite et sa selectivite, en faisant varier l'acidite et/ou la porosite. L'ensemble des resultats obtenus montre que de nombreux parametres, tels que la temperature, la nature de l'agent acylant ou alkylant, la nature du solvant, l'acidite et la porosite du catalyseur influent sur les vitesses des reactions d'alkylation et d'acylation du thiophene. L'effet de la porosite semble tout particulierement important, car il modifie profondement la selectivite des reactions. Il est cependant difficile d'etendre ces conclusions a d'autres reactions similaires, chaque cas necessitant une etude systematique de l'influence des divers parametres
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Karrepu, Venkateswara Reddy. "FRIEDEL-CRAFTS ACYLATION STUDIES ON 3-ALKYL-1-(PHENYLSULFONYL)INDOLES USING ALUMINUM CHLORIDE AND BISMUTH TRIFLATE." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1333733182.

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Montagne, Fabienne. "Les sels de terres rares en catalyse hétérogène des réactions de Friedel-Crafts : applications en polycondensation." Dijon, 1997. http://www.theses.fr/1997DIJOS033.

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En chimie fine, le réactif universel des réactions d'alkylation et d'acylation de composés aromatiques selon Friedel-Crafts est le trichlorure d'aluminium mais l'emploi de cet acide de Lewis présente plusieurs inconvénients : la réaction est au mieux stoechiométrique, le réactif est d'un usage unique et les effluents sont nuisibles à l'environnement. Les sels de terres rares déposés sur un support minéral sont d'excellents catalyseurs des réactions de Friedel-Crafts ; leur activité catalytique est nettement plus élevée que celle des chlorures de terres rares et leurs analogues coordonnés non supportés. Les conditions opératoires sont douces, l'isolement des produits ne nécessite pas d'hydrolyse et les catalyseurs, facilement éliminés du milieu réactionnel par simple filtration, sont recyclables. Différentes techniques d'analyse ont été utilisées pour caractériser les catalyseurs supportés et étudier l'influence des divers traitements sur la nature de l'espèce déposée. Après avoir évalué leurs performances catalytiques dans deux réactions tests, la gamme de réactivité des catalyseurs supportés a été étudiée. Les catalyseurs supportés ont également été étudiés dans des réactions conduites sous irradiation micro-ondes. Les différents tests ont confirmé qu'un accroissement de la température, module par la puissance du rayonnement micro-ondes, s'accompagne d'une augmentation du rendement ; la sélectivité est semblable à celle obtenue pour les réactions effectuées en chauffage traditionnel. L'application des réactions d'alkylation de type Friedel-Crafts à des réactions de polycondensation a conduit à la synthèse de nouveaux polybenzyles solubles, dont les caractéristiques physico-chimiques ont été déterminées.
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Fishlock, Daniel. "The Catalytic Intramolecular Friedel-Crafts Acylation of Meldrum's Acid Derivatives and The Total Synthesis of Taiwaniaquinol B." Thesis, University of Waterloo, 2005. http://hdl.handle.net/10012/1226.

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The intramolecular Friedel-Crafts acylation of aromatics with Meldrum?s acid derivatives catalyzed by metal trifluoromethanesulfonates and other Lewis acids is reported. Meldrum?s acids are easily prepared, functionalized, handled, and purified. The synthesis of polysubstituted 1-indanones from benzyl Meldrum's acids was investigated thoroughly, and it was shown that a variety of catalysts were effective, whilst accommodating a diversity of functional groups under mild conditions. The scope, limitations, and functional group tolerance (terminal alkene and alkyne, ketal, dialkyl ether, dialkyl thioether, aryl methyl ether, aryl TIPS and TBDPS ethers, nitrile- and nitro-substituted aryls, alkyl and aryl halides) for a variety of 5-benzyl (enolizable Meldrum?s acids) and 5-benzyl-5-substituted Meldrum?s acids (quaternarized Meldrum?s acids), forming 1-indanones and 2-substituted-1-indanones respectively, are delineated.

This method was further applied to the synthesis of 1-tetralones, 1-benzosuberones, and the potent acetylcholinesterase inhibitor donepezil.

Mechanistic investigations were undertaken to determine the rate-determining step in the acylation sequence using Meldrum?s acid, as well as to examine the role of the Lewis acid catalyst. Enolizable Meldrum?s acid derivatives can react via an acyl ketene intermediate under thermal conditions, while quaternarized Meldrum?s acid derivatives are thermally stable and only act as effective Friedel-Crafts acylating agents in the presence of a Lewis acid catalyst.

The total synthesis of (±)-Taiwaniaquinol B was completed. This natural product was the first ever isolated containing an unusual 6-5-6 fused ring system, and it also contains a hexasubstituted aromatic ring, and two all-carbon quaternary centers. This synthesis was accomplished via an intramolecular Friedel-Crafts acylation/carbonyl a-tert-alkylation reaction that exploits the unique chemistry of Meldrum?s acid. This novel methodology can be used to access a variety of highly substituted fused ring systems of various sizes.
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NASS, OLIVIER. "Syntheses et reactions de complexes spiraniques de dienes fer-tricarbonyle : acylation intramoleculaire de friedel-crafts et cyclocarbonylation." Université Louis Pasteur (Strasbourg) (1971-2008), 1997. http://www.theses.fr/1997STR13230.

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La decomplexation avec carbonylation de dienes fer tricarbonyle 1,1,3-trisubstitues a ete reexaminee en vue d'un acces stereocontrole a des sesquiterpenes spiro4. 5decaniques. Les complexes precurseurs ont ete prepares par homologation de cyclohexanones par transposition de meyer-schuster, conversion en dienes exocycliques et complexation diastereoselective. L'etude de cette cycloaddition 4+1 formelle a permis de verifier sa stereospecificite, l'accessibilite de cyclopenten-2-ones spirobicycliques et tricycliques, et de preciser les possibilites et limites d'ordre sterique du procede. L'acylation intramoleculaire de friedel-crafts, inedite pour ces complexes de fer, a d'autre part ete examinee au depart de derives dieniques substitues en position 1 par un residu carboxyalkyle. Apres optimisation, les cycles a 5 et 6 carbonnes ont ete formes avec des rendements respectifs de 75 et 55%. Un acces simple et rapide a des complexes de 2h-pyrannes bicycliques inedits, analogues heterocycliques des cyclohexadienes fer tricarbonyle, a par ailleurs ete mis en evidence. Un important potentiel synthetique est envisageable pour ces composes. Une reflexion a ete engagee sur l'interet general de la sous-structure diene fer tricarbonyle en tant que groupement stereodirecteur. La synthese de complexes optiquement purs par complexation diastereoselective, et la modification stereoselective de cetones et d'alcools au voisinage immediat du site de coordination ont ete analyses, documentes et illustres par des exemples concrets. Ce memoire revele les caracteristiques reactionnelles et structurales inhabituelles des complexes de dienes exocycliques prepares. Il est d'autre part illustratif de divers concepts stereochimiques, de l'incidence des ruptures de symetrie sur le deroulement d'une reaction, et de l'interet particulier des composes meso et de la notion de pseudoasymetrie.
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Books on the topic "Friedel-Crafts acylation"

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Sartori, Giovanni. Advances in Friedel-Crafts acylation reactions: Catalytic and green processes. Boca Raton: Taylor & Francis, 2010.

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Sartori, Giovanni. Advances in Friedel-Crafts acylation reactions: Catalytic and green processes. Boca Raton: Taylor & Francis, 2010.

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Maggi, Raimondo, and Giovanni Sartori. Advances in Friedel-Crafts Acylation Reactions: Catalytic and Green Processes. Taylor & Francis Group, 2017.

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Maggi, Raimondo, and Giovanni Sartori. Advances in Friedel-Crafts Acylation Reactions: Catalytic and Green Processes. Taylor & Francis Group, 2009.

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Sartori, Giovanni. Advances in Friedel-Crafts Acylation Reactions: Catalytic and Green Processes. CRC, 2009.

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Book chapters on the topic "Friedel-Crafts acylation"

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Sartori, Giovanni, Raimondo Maggi, and Veronica Santacroce. "Catalytic Friedel-Crafts Acylation Reactions." In Arene Chemistry, 59–82. Hoboken, NJ: John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118754887.ch3.

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Patil, Abhimanyu O. "A Novel Reactive Functionalization of Polyolefin Elastomers: Direct Functionalization of Poly(isobutylene-co-p-methylstyrene) by a Friedel-Crafts Acylation Reaction." In ACS Symposium Series, 184–98. Washington, DC: American Chemical Society, 1998. http://dx.doi.org/10.1021/bk-1998-0704.ch013.

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Yoon, T. P., and E. N. Jacobsen. "Friedel–Crafts Acylation." In Three Carbon-Heteroatom Bonds: Acid Halides; Carboxylic Acids and Acid Salts, 1. Georg Thieme Verlag KG, 2007. http://dx.doi.org/10.1055/sos-sd-020-01203.

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Campagne, J. M., and Y. Six. "Friedel–Crafts Acylation." In Ketones, 1. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-026-00950.

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Oestreich, M. "Friedel–Crafts Acylation." In Aldehydes, 1. Georg Thieme Verlag KG, 2007. http://dx.doi.org/10.1055/sos-sd-025-00474.

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Landais, Y., and J. M. Vincent. "Friedel–Crafts Acylation." In Ketones, 1. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-026-00542.

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Oshima, K. "Friedel–Crafts Acylation." In Compounds of Groups 15 (As, Sb, Bi) and Silicon Compounds, 1. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-004-00809.

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Camp, J. E. "Friedel–Crafts Acylation." In Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-117-00111.

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Toyota, S., and T. Iwanaga. "Friedel–Crafts Acylation." In Monocyclic Arenes, Quasiarenes, and Annulenes, 1. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-045-00851.

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Andrews, M. D. "Friedel–Crafts Acylation." In Fused Five-Membered Hetarenes with One Heteroatom, 1. Georg Thieme Verlag KG, 2001. http://dx.doi.org/10.1055/sos-sd-010-00336.

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Conference papers on the topic "Friedel-Crafts acylation"

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"Friedel Crafts Acylation of Anisole With Modified Zeolites." In ISECT-2017, BDAMTE-17, IDCE-2017, CCES-2017, ICHBES-2017, MBPS-2017, ACBES-17, LHHIS-17, LBETM-17, AFPIS-2017 & EFEAM-2017. Dignified Researchers Publication (DiRPUB), 2018. http://dx.doi.org/10.15242/dirpub.dir1017204.

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Frost, Christopher, and Joseph Hartley. "Indium triflate: An Efficient Catalyst For The Friedel-Crafts Acylation of Aromatics." In The 4th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01846.

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