Academic literature on the topic 'Fracture healing'

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Journal articles on the topic "Fracture healing"

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Engelhardt, Lucas, Frank Niemeyer, Patrik Christen, Ralph Müller, Kerstin Stock, Michael Blauth, Karsten Urban, Anita Ignatius, and Ulrich Simon. "Simulating Metaphyseal Fracture Healing in the Distal Radius." Biomechanics 1, no. 1 (February 25, 2021): 29–42. http://dx.doi.org/10.3390/biomechanics1010003.

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Simulating diaphyseal fracture healing via numerical models has been investigated for a long time. It is apparent from in vivo studies that metaphyseal fracture healing should follow similar biomechanical rules although the speed and healing pattern might differ. To investigate this hypothesis, a pre-existing, well-established diaphyseal fracture healing model was extended to study metaphyseal bone healing. Clinical data of distal radius fractures were compared to corresponding geometrically patient-specific fracture healing simulations. The numerical model, was able to predict a realistic fracture healing process in a wide variety of radius geometries. Endochondral and mainly intramembranous ossification was predicted in the fractured area without callus formation. The model, therefore, appears appropriate to study metaphyseal bone healing under differing mechanical conditions and metaphyseal fractures in different bones and fracture types. Nevertheless, the outlined model was conducted in a simplified rotational symmetric case. Further studies may extend the model to a three-dimensional representation to investigate complex fracture shapes. This will help to optimize clinical treatments of radial fractures, medical implant design and foster biomechanical research in metaphyseal fracture healing.
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Gajdobranski, Djordje, and Dragana Zivkovic. "Impaired fracture healing." Medical review 56, no. 3-4 (2003): 146–51. http://dx.doi.org/10.2298/mpns0304146g.

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Introduction Bone fracture healing is a complex cascade of events at cellular and biochemical levels, that ends by complete structural and functional restoration of a damaged bone. Impaired healing develops in 5-10% of all fractures, and manifests as delayed union or non-union. This paper deals with the problem of impaired healing as well as with methods of fracture healing enhancement. Causes of impaired fracture healing There are many factors causing impaired fracture healing (inadequate vascularization, mechanical causes, infection, etc.), and it is very important to recognize the principle cause of delayed union and non-union, since therapy is based on eliminating the factor that causes it. Fracture healing enhancement Through constant attempts to find adequate solutions and procedures in order to resolve the problem of impaired fracture healing, many alternatives in treatment of impaired healing have been developed. Some of these procedures may also be useful in treatment of fresh fractures, especially when it comes to fractures that are prone to delayed union and non-union more than usual. All currently known methods of healing enhancement may be classified as biological, mechanical and biophysical. Conclusion Certain methods are in clinical use for several decades. The newest methods, such as locally applied growth factors, composite biosynthetic grafts, gene therapy and systemic approaches are studied all around the world, and are on the verge of clinical application. Due to impressive number of therapeutic options, certain therapeutic procedures of choice will be developed for specific impairments.
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Omar, Raffal A., and S. I. Saleh. "Study of low power Laser effect on the healing of tibial fracture treated by intramedullary pin in rabbits." Iraqi Journal of Veterinary Medicine 27, no. 1 (June 28, 2003): 99–108. http://dx.doi.org/10.30539/ijvm.v27i1.1100.

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The effect of low power laser (LPL) on the healing of distal third of tibial fractures has been studied radiologically. Fractures induced in twenty-five local breed rabbits, immobilization achieved by using Steinman intramedullary pins, which was not removed during the period of study for 7 weeks. Irradiation with LPL was made by direct contact between the source and the site of fracture directly after the operation and then daily for fifteen days. Each fracture was studied radiologically after the first day from the operation until complete healing occurs. This study confirm that the healing of distal third of tibial fracture was very slow in control group and LPL accelerate the process of fracture healing in treated groups. With notice that the surface of fractured bone exposed to the source of laser therapy (medial side) was healed better than the non - exposed surface (lateral side). Finally there was no clear difference between treated groups.
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Wollstein, Ronit, Arie Trouw, Lois Carlson, Ilene Staff, Daniel J. Mastella, and Duffield Ashmead. "The Effect of Age on Fracture Healing Time in Metacarpal Fractures." HAND 15, no. 4 (December 2, 2018): 542–46. http://dx.doi.org/10.1177/1558944718813730.

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Background: Older patients are treated for fracture with increasing frequency. Although studies on animals suggest that older mice and rats heal fractures more slowly, the clinical implications remain unclear. A better understanding of differences in healing with age can help customize fracture treatment. Our purpose was to retrospectively evaluate metacarpal fractures for healing time looking specifically at age-related differences. Methods: A retrospective review of patients treated for metacarpal fractures was conducted. Patients with incomplete charts or inadequate follow-up were excluded. One hundred ninety-eight charts were analyzed. Demographic and other patient factors were documented. Fracture characteristics and treatment type were documented. Fracture healing was determined clinically. Plain radiographs and examination were used in decision making. Results: Age was not associated with fracture healing time as a continuous variable ( P = .09). Patients above 75 years were not associated with increased healing time ( P = .58). Fracture characteristics were related to healing time: minimally displaced and comminuted fractures healed faster than oblique fractures, spiral fractures, or transverse fractures ( P = .048). Patients undergoing surgery healed faster than those without surgery ( P = .046). Renal failure negatively affected fracture healing time ( P = .03). Diabetes, hypothyroidism, and gender were not associated with healing time. Complications were not associated with age or other patient or fracture-related factors. Conclusions: Age does not affect clinical fracture healing time in adult. Therefore, older patients do not require disparate treatment. Other fracture-related factors and considerations such as functional demand and support systems might influence treatment decisions in fracture care.
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Smith, Robert G. "Fracture Healing." Journal of the American Podiatric Medical Association 105, no. 2 (March 1, 2015): 160–72. http://dx.doi.org/10.7547/0003-0538-105.2.160.

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Background Recognizing the existence of adverse drug effects of frequently prescribed drugs can empower a clinician with knowledge to avoid dangerous adverse effects that may result in hazardous, negative patient outcomes on either fracture healing or bone health. Pharmacovigilance reports have described the influence of medications, allowing for bone health to be quite unpredictable. Methods First, mechanisms found in the medical literature of potential drug adverse effects regarding fracture healing are presented. Second, the 100 most frequently prescribed medications in 2010 are reviewed regarding adverse effects on fracture healing. These reported adverse effects are evaluated for medical causation. Last, a data table describing the 100 reviewed medications and their reported effects on fracture healing is provided. Results The actual number of different medications in the review was 72. Reported drug adverse effects on bone and fracture healing occurred with 59 of the 72 drugs (81.9%). These adverse effects are either described as a definitive statement or represented by postmarketing case reports. Thirteen of the 72 review drugs (18.1%) did not have any description of the possible effects on bone health. A total of 301 cases reports describing delayed union, malunion, and nonunion of fractures represent 31 of the 72 medications reviewed (43.1%). Conclusions This review offers the health-care provider information regarding potential adverse drug effects on bone health. Empowered with this information, clinicians may assist their patients in maximizing pharmacologic outcomes by avoiding these reported harmful adverse effects.
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Raschke, Michael, Michael Højby Rasmussen, Shunmugam Govender, David Segal, Mette Suntum, and Jens Sandahl Christiansen. "Effects of growth hormone in patients with tibial fracture: a randomised, double-blind, placebo-controlled clinical trial." European Journal of Endocrinology 156, no. 3 (March 2007): 341–51. http://dx.doi.org/10.1530/eje-06-0598.

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Objective: Investigate whether intervention with GH after tibial fracture enhances fracture healing. Design: Randomised, double-blind, placebo-controlled study in 406 patients (93 women, 313 men, age: 18–64 years) with tibial fracture. Methods: Patients were stratified by tibial fracture (open or closed) and allocated to placebo or GH treatment (15, 30 or 60 μg/kg daily, until clinically assessed healing or until 16 weeks post-surgery). Primary outcome was time from surgery until fracture healing and assessment of healing was done centrally and observer blinded. Patients reported for evaluation every 4 weeks until 24 weeks, and at 9 and 12 months. Results: GH did not accelerate time to healing in the combined group of open and closed fractures. When separately analysing the closed and open fractures, a significant difference in time to healing was observed between treatment groups, exclusively in the closed fractures (P<0.05; subgroup analysis revealed that the 60 μg/kg group was significantly different from placebo). The relative risk of fracture healing for 60 μg/kg versus placebo during the 12 month was: all fractures, 1.16; 95% CI: (0.86; 1.57) (ns); closed fractures, 1.44; 95% CI: (1.01; 2.05; P<0.05); open fractures, 0.75; 95% CI: (0.42; 1.31) (ns). The estimated median number of days before fracture healing in closed fractures was 95 with 60 μg/kg versus 129 with placebo (95% CI: (94; 129) and (94; 249)) corresponding to approximately 26% decrease in healing time. Conclusions: In the overall group of open and closed tibial fractures, no significant enhancement of fracture healing was observed with GH, whereas in closed tibial fractures, GH accelerated healing significantly.
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Johnson, Ann L., M. Chambers, C. W. Smith, S. Kneller, A. R. Twardock, D. J. Schaeffer, and S. M. Averill. "Qualitative and Quantitative Scintigraphic Imaging to Predict Fracture Healing." Veterinary and Comparative Orthopaedics and Traumatology 12, no. 03 (1999): 142–50. http://dx.doi.org/10.1055/s-0038-1632480.

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SummaryPurpose: Evaluate the value of 24- hour postoperative quantitative bone scintigraphy to identify devascularized fragments and predict delayed fracture bridging in canine clinical patients; to determine the effect of fracture type, fixation type, age, sex, and weight on fracture bridging and the quantitative scintigraphic ratios; and to evaluate the relationship between qualitative scintigraphic assessment and quantitative scintigraphic ratios. Methods: Forty-two adult dogs, with diaphyseal long bone fractures treated with minimally invasive biological or invasive surgical techniques, were evaluated with 24-hour postoperative bone scintigraphy and six and 12 week postoperative radiographs. Fractured bones were classified as simple, moderately multiple, or severely multiple. Bone scintigrams were qualitatively and quantitatively analyzed. Radiographs were made at six and 12 weeks after the operation and graded as fracture gap(s) bridged or not bridged with bone opacity material. The data was evaluated statistically to determine the relationship between age, sex, and weight of the dogs, fracture type, fixation type, and results of scintigram analysis to fracture bridging at six and 12 weeks. Results: Fourteen of the 42 fractures were bridged at six weeks after the operation and 33 at 12 weeks. Prediction of fracture healing was not possible. There was not any statistical relationship of fracture type, fixation, sex, nor weight to bridged fractures or non-bridged fractures at six and 12 weeks. There was a trend toward more of the fractures with multiple fragments treated with minimally invasive biological techniques to be bridged by 12 weeks when compared to similar fractures treated with invasive techniques. The mean age of dogs with bridged fractures at six and 12 weeks was significantly lower than the mean age of dogs with non-bridged fractures at six and 12 weeks. Qualitative scintigraphic assessment scores were not significantly related to the quantitative scintigraphic ratios or to fracture bridging. Conclusions: Neither qualitative nor quantitative assessment of bone scintigrams 24 hours after the operation could be used to predict fracture bridging at six or 12 weeks postoperatively.The value of 24-hour postoperative qualitative and quantitative bone scintigraphy to predict fracture bridging by 12 weeks in canine clinical patients with diaphyseal long bone fractures was evaluated. Neither qualitative nor quantitative assessment of bone scintigrams 24 hours after the operation could be used to predict fracture bridging by 12 weeks.Supported in part by a grant from the AO Vet Centre, Zurich, Switzerland.
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Wank, Isabel, Tanja Niedermair, Daniel Kronenberg, Richard Stange, Christoph Brochhausen, Andreas Hess, and Susanne Grässel. "Influence of the Peripheral Nervous System on Murine Osteoporotic Fracture Healing and Fracture-Induced Hyperalgesia." International Journal of Molecular Sciences 24, no. 1 (December 28, 2022): 510. http://dx.doi.org/10.3390/ijms24010510.

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Osteoporotic fractures are often linked to persisting chronic pain and poor healing outcomes. Substance P (SP), α-calcitonin gene-related peptide (α-CGRP) and sympathetic neurotransmitters are involved in bone remodeling after trauma and nociceptive processes, e.g., fracture-induced hyperalgesia. We aimed to link sensory and sympathetic signaling to fracture healing and fracture-induced hyperalgesia under osteoporotic conditions. Externally stabilized femoral fractures were set 28 days after OVX in wild type (WT), α-CGRP- deficient (α-CGRP −/−), SP-deficient (Tac1−/−) and sympathectomized (SYX) mice. Functional MRI (fMRI) was performed two days before and five and 21 days post fracture, followed by µCT and biomechanical tests. Sympathectomy affected structural bone properties in the fracture callus whereas loss of sensory neurotransmitters affected trabecular structures in contralateral, non-fractured bones. Biomechanical properties were mostly similar in all groups. Both nociceptive and resting-state (RS) fMRI revealed significant baseline differences in functional connectivity (FC) between WT and neurotransmitter-deficient mice. The fracture-induced hyperalgesia modulated central nociception and had robust impact on RS FC in all groups. The changes demonstrated in RS FC in fMRI might potentially be used as a bone traumata-induced biomarker regarding fracture healing under pathophysiological musculoskeletal conditions. The findings are of clinical importance and relevance as they advance our understanding of pain during osteoporotic fracture healing and provide a potential imaging biomarker for fracture-related hyperalgesia and its temporal development. Overall, this may help to reduce the development of chronic pain after fracture thereby improving the treatment of osteoporotic fractures.
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Bottai, Vanna, Gabriele Gariffo, Edoardo Ipponi, Roberta Cifali, Nicola Mondanelli, and Stefano Giannotti. "Use of teriparatide in preventing delayed bone healing in complex biosseous leg fracture: a case report." International Journal of Bone Fragility 1, no. 1 (March 20, 2021): 14–16. http://dx.doi.org/10.57582/ijbf.210101.014.

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Fracture nonunion is one of the greatest challenges for orthopedic surgeons. We present the case of a young man with a complex open biosseous fracture of the leg who underwent surgery and early systemic pharmacological treatment with teriparatide. Teriparatide is widely used in the treatment of osteoporosis as its anabolic effects promote the deposition of new bone tissue. Associated tibia and fibula fractures have relatively high rates of nonunion and poor long-term outcomes. In this particular case, the fracture had further negative prognostic factors, such as exposure. Two months after the trauma, the radiological healing signs were insufficient, therefore it was decided to use teriparatide, prior to the possible onset of pseudarthrosis, in order to enhance bone healing and promote adequate callus formation. Complete healing of the fracture was achieved after 99 days of treatment. The authors believe that the use of pharmacological aids may be desirable, especially in the presence of risk factors such as complex and open fractures that could seriously slow down the natural regenerative processes of the fractured bone. In this scenario, teriparatide could have an important role in preventing delayed consolidation and improving the healing of nonunion fractures.
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Raghavan, Pooja, and Elena Christofides. "Role of Teriparatide in Accelerating Metatarsal Stress Fracture Healing: A Case Series and Review of Literature." Clinical Medicine Insights: Endocrinology and Diabetes 5 (January 2012): CMED.S9663. http://dx.doi.org/10.4137/cmed.s9663.

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Bone fractures are one of the leading causes of emergency room visits worldwide, with approximately 8 million bony fractures occurring annually in the US alone. Although the majority of fractures do not cause significant long-term morbidity and mortality, approximately 10% of these fractures result in impaired fracture healing, drastically affecting quality of life in affected patients. By increasing bone formation, teriparatide, an anabolic agent used in the treatment of postmenopausal osteoporosis, has shown promise in accelerating the rate of fracture healing. We present two patients with impaired healing of metatarsal fractures who were subsequently treated with teriparatide. Both patients experienced successful bony union of the fracture after the use of teriparatide. These findings suggest that teriparatide may be useful in the clinical setting for the acceleration of fracture healing, especially in patients who are at risk for impaired fracture healing.
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Dissertations / Theses on the topic "Fracture healing"

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Sandberg, Olof. "Metaphyseal Fracture Healing." Doctoral thesis, Linköpings universitet, Avdelningen för kliniska vetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-126148.

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Most of what is known about fracture healing comes from studies of shaft fractures in long bones. In contrast, patients more often have fractures closer to the ends (metaphyses). Here most bone tissue has a spongy, cancellous structure different from the compact bone of the shaft. There is an increasing awareness that metaphyseal fractures heal differently. However, the more easily studied shaft healing has usually been considered as good enough representative for fracture healing in general. My work shows that the biology of metaphyseal healing is more different from shaft healing than was previously known and that this has implications on the effect of various commonly prescribed drugs. First we studied biopsies of healing cancellous bone collected from human donors. We found that the most abundant new bone formation occurred freely in the marrow rather than on the surface of old trabeculae, as described in most literature. There was little cartilage, indicating that the dominant bone formation process is mostly membranous in nature. This is a contrast to the ample cartilage formation commonly found in the well-characterized shaft fracture models. Next we characterized a model that allows for mechanical quantification of regenerating cancellous bone. By contrasting this cancellous healing model with the standard shaft healing model we could demonstrate that the NSAID indomethacin, the glucocorticoid dexamethasone, and the bisphosphonate alendronate all had different effects on the mechanical quality of bone regeneration in shaft and metaphysis; while anti-inflammatory drugs strongly impaired shaft healing, metaphyseal healing was not similarly affected. Alendronate had a positive effect on both models, though the effect was strongest in the metaphyseal model. Taken together these differences shed some light as to the differences in healing biology. The last step (within the boundaries of this thesis) was a characterization of how healing in cortical and cancellous bone differs in terms of immune cell involvement. We could find little difference between the two bone types day 3. However, day 5 an increase in the number of granulocytes could be noted in the cancellous bone while the cortical bone had a higher number of lymphocytes. To conclude, this work furthers our understanding of how metaphyseal healing differs from shaft healing. It has clinical implications as it motivates an increased attention to the site of fracture while contemplating treatment. I hope this thesis can be read as an argument for increased interest in metaphyseal fracture healing.
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Hardy, John R. W. "Tibial diaphyseal fracture healing." Thesis, University of Leicester, 1996. http://hdl.handle.net/2381/34096.

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Gill, Peter John. "Ultrasonic assessment of fracture healing." Thesis, Queen's University Belfast, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356863.

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Richardson, James Bruce. "The mechanics of fracture healing." Thesis, University of Aberdeen, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.290866.

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The mechanics applied to healing fractures vary widely. At one extreme rigid internal fixation is advocated, while at the other early mobilisation is recommended using external splints. Kuhn's method of paradigm orientated research was used to define the historical context of current assumptions regarding fracture healing. Conflict between the various schools of thought is the main evidence for failure of these assumptions and the need to evolve a new perspective on fracture healing. A paradigm is presented which proposes healing by external callus as an early stage and 'primary healing' as the later stage as of one continuous but changing process. A fundamental hypothesis was tested: that mechanics is the major control of fracture healing in man. A multicentre study of 102 patients with serious fractures were treated with external skeletal fixation. In 60 patients rigid external fixation was applied. In the remaining 42 the same fixation device was used, but adapted to apply 1 to 2mm of cyclic axial micromovement across the fracture. A piston applied 500 cycles of movement over a 30 minute period each day until this could be achieved by the patient on weight-bearing. Objective assessment required development of new techniques of measuring fracture stiffness and defining the point of healing. This objective measure, and clinically defined healing, were significantly faster in the group treated with micromovement (two-way analysis of variance, p = 0.005 and 0.03, respectively). Repeated injury by plastic deformation is proposed to maintain callus growth in the first phase of healing. Evidence for the required parameters of movement was gathered from the trial of micromovement, from measurements in 4 cases of epiphyseolysis and also 8 patients undergoing arthrodesis. It would appear appropriate to apply cyclic axial displacement of 2mm within the first two weeks from injury and of consistent direction until sufficient bulk of callus is formed. Thereafter axial compaction is appropriate in a second phase where callus matures. The mechanics that govern remodelling were considered to apply to the final phase. Failure of a cell culture model to display obvious results from cyclic loading may indicate that the response to mechanical loading is indirect. Intermediate and mechanically dependent biochemical and bioelectrical factors are discussed.
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Wade, Roger. "Defining fracture union." Thesis, Keele University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249450.

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Shroff, Malav. "Effect of age on fracture healing." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393369.

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Gheduzzi, Sabina. "Fracture healing assessment by quantitative ultrasound measurements." Thesis, University of Bath, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341701.

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Dawson, Sarah P. "Digital X-ray analysis for monitoring fracture healing." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/4285.

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X-ray based evaluation of different stages of fracture healing is a well established clinical standard. However, several studies have shown plain radiography alone to be an unreliable method to assess healing. The advent of digital X-ray systems provides the potential to perform quantitative analysis on X-ray images without disrupting normal clinical practice. Two aspects were explored in this study. The first was the measurement of mechanical fracture stiffness under four point bending and axial loading. The second was the inclusion of an Aluminium step wedge to provide Aluminium-equivalent thickness calibration information. Mechanical sti ness studies involved the development of equipment to perform four point bending on intra-medullary (IM) nailed tibial fractures, equipment to perform axial loading on conservatively treated humeral fractures, and fracture models to ex- amine the developed systems. Computational procedures to automatically measure the angle and offset occurring at the fracture site by comparing loaded and unloaded X-ray images were developed utilising cross-correlation. The apparatus and procedures were tested using the fracture models both in X-ray and using the Zwick materials testing machine. The four point bending system was applied clinically to a series of IM nailed tibial fracture patients and the axial loading system to two conservatively treated humeral fracture patients. Mechanical stiffness results showed that the apparatus worked well in the clinical radiography environment and was unobtrusive to normal practice. The developed X-ray analysis procedure provided reliable measurements. However, in the case of IM nailed tibial fractures, both angular and displacement movements were too small to be accurately assessed or to provide reliable stiffness measurements. This indicated that this patient group was possibly unsuitable for mechanical stiffness measurements or that higher loads needed to be applied to the fracture site. The case studies of conservatively treated humeral fractures showed potential in detecting movement between loaded and unloaded X-rays and using this to provide sti ness information. Further investigation is required to show that this technique has the potential to aid fracture healing monitoring. Investigation into Aluminium step wedge calibration began with the design of different step wedges and X-ray phantoms. Initial image analysis involved studying the automatic processing applied by a digital Computed Radiography (CR) Fuji sys- tem and modelling of the inhomogeneities in X-ray images as well as investigation into the effect of and correction for scatter, overlying soft tissue and bone thickness. Computational procedures were developed to semi-automatically detect the steps of the step wedge, form an exponential Aluminium step thickness to grey level calibration graph, measure soft tissue and bone thickness, and correct for the heel effect and scatter contributions. Tests were carried out on pre-clinical models and results compared to ash weight and peripheral quantitative computed tomography (pQCT). A clinical study of radial fractures was used to investigate the effectiveness of the step wedge calibration system in monitoring fracture healing changes. Results using the step wedge indicated that the calibration technique was e ective in detecting and correcting for aspects in uencing Aluminium-equivalent thickness measures. With careful processing, useful information was obtained from digital X- rays that included the Aluminium step wedge and these correlated well with existing density measures. The use of the wedge in patient images showed that small increases in Aluminium-equivalent thickness of the fracture site could be detected. This was most useful for intra-patient comparisons throughout the course of healing rather than providing quantitative measurements which were comparable to other density measures. In conclusion, this thesis shows the potential for accurate analysis of digital X- rays to aid the monitoring of healing changes in fracture patients, particularly with application of axial loading and the use of step wedge calibration.
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Li, Jiang, and 李江. "Bone fracture healing in laminopathy-based premature aging." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45142233.

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Shirley, D. S. L. "Osteoblastic cells are systemically recruited during fracture healing." Thesis, Queen's University Belfast, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401767.

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Books on the topic "Fracture healing"

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1939-, Lane Joseph M., American Orthopaedic Association, and Orthopaedic Research and Education Foundation., eds. Fracture healing. New York: Churchill Livingstone, 1987.

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Claes, Lutz E. Mechanobiology of Fracture Healing. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94082-9.

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A, Martinez Steven, ed. Fracture management and bone healing. Philadelphia: W.B. Saunders, 1999.

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Knoch, Hans-Georg, and Winfried Klug. Stimulation of Fracture Healing with Ultrasound. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76427-1.

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Chan, Raymond. Quantitative assessment of fracture healing stiffness. Ottawa: National Library of Canada, 1992.

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Charnley, John. The Closed treatment of common fractures. 4th ed. Cambridge: Colt Books in association with The John Charnley Trust, 1999.

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Mehta, Samir. Orthobiologics: Improving fracture care through science. Philadelphia: Wolters Kluwer Health/Lippincott Wiliams & Wilkins, 2007.

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D, Johnson Kenneth, ed. Biomechanics in orthopedic trauma: Bone fracture and fixation. London: M. Dunitz, 1994.

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Laycock, D. C. Vibration analysis of fracture healing in long bones. Salford: University of Salford, 1991.

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Stafford, Hilary Jane. Fracture healing in a rabbit model: A study of osteocalcin localisation. Leicester: De Montfort University, 1993.

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Book chapters on the topic "Fracture healing"

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Arazi, Mehmet, and Mehmet Kerem Canbora. "Fracture Healing." In Musculoskeletal Research and Basic Science, 323–41. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-20777-3_19.

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Wessel, Bryan E., and David P. Duncan. "Fracture Healing." In Essential Radiology Review, 441–44. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-26044-6_135.

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Perren, S. M. "Fracture Healing." In Osteosynthesis in the Hand: Current Concepts, 4–11. Basel: KARGER, 2008. http://dx.doi.org/10.1159/000138575.

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Morshed, Saam, and Anthony Ding. "Fracture Healing." In Nonunions, 45–74. Boston, MA: Springer US, 2017. http://dx.doi.org/10.1007/978-1-4939-7178-7_2.

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Bartl, Reiner, and Christoph Bartl. "Fracture Healing." In Bone Disorders, 239–42. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29182-6_35.

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Bartl, Reiner, and Christoph Bartl. "Fracture Healing." In The Osteoporosis Manual, 237–40. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-00731-7_30.

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Haffner, Nicolas, Daniel Smolen, and Rainer Mittermayr. "Fracture Healing." In Principles of Bone and Joint Research, 99–124. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58955-8_7.

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De Marchi, Armanda, Davide Orlandi, Enzo Silvestri, Luca Cavagnaro, and Alessandro Muda. "Bone Fracture Healing." In Musculoskeletal Ultrasound in Orthopedic and Rheumatic disease in Adults, 215–18. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-91202-4_24.

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Sampaio, Marcos Loreto. "Fracture Healing and Complications of Fractures." In Imaging Musculoskeletal Trauma, 341–77. Oxford: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118551691.ch10.

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Bååth, Carina, and Ami Hommel. "Wound Management." In Perspectives in Nursing Management and Care for Older Adults, 159–70. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-33484-9_10.

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AbstractWound healing is the process by which the function of damaged tissue is restored following surgery, trauma or other sources of tissue damage. The management of wounds is a fundamental aspect of the management of the patient following a fragility fracture, especially following a hip fracture and associated surgery. Ageing skin and multiple comorbidities are significant factors in skin injury and wound healing problems.The effective evidence-based management of surgical wounds following surgery after a fragility fracture can be challenging as ageing and comorbidities affect wound healing. Skin and wound care involves careful skin and wound assessment and attention to infection prevention measures while managing the factors affecting wound healing. Clinical considerations in wound management also include maintaining adequate nutrition, moisture, treating oedema and preventing further injury.This chapter aims to provide an overview of skin and wound assessment and evidence-based care interventions that can optimise wound healing in older people with fragility fractures.
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Conference papers on the topic "Fracture healing"

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Ebrom, D. A., Ines Sauthoff, J. A. McDonald, and Robert H. Tatham. "Fracture healing and normal stress." In SEG Technical Program Expanded Abstracts 1991. Society of Exploration Geophysicists, 1991. http://dx.doi.org/10.1190/1.1888833.

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Santoni, Brandon G., Rohat Melik, Emre Unal, Nihan Kosku Perkgoz, Debra A. Kamstock, Stewart D. Ryan, William S. Dernell, Hilmi Volkan Demir, and Christian M. Puttlitz. "Development and Biocompatibility Characterization of a BioMEMS Sensor for Monitoring the Progression of Fracture Healing." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206670.

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Orthopaedic extremity injuries present a large medical and financial burden to the United States and world-wide communities [1]. Approximately six million long bone fractures are reported annually in the United States and approximately 10% of these fractures do not heal properly. Though the exact mechanism of impaired healing is poorly understood, many of these non-unions result when there is a communited condition that does not proceed through a stabilized healing pathway [2]. Currently, clinicians may monitor healing visually by radiographs, or via manual manipulation of the bone at the fracture [3]. Unfortunately, the course of aberrant fracture healing is not easily diagnosed in the early period when standard radiographic information of the fracture is not capable of discriminating the healing pathway. Manual assessment of fracture healing is also an inadequate diagnostic tool in the early stages of healing [4].
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Lin, Monica C., Safa T. Herfat, Chelsea S. Bahney, Meir Marmor, and Michel M. Maharbiz. "Impedance spectroscopy to monitor fracture healing." In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7319548.

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Kimura, Satoshi, Keisuke Oe, Yohei Kumabe, Tomoaki Fukui, Takahiro Niikura, Ryosuke Kuroda, Naomi Yagi, and Yutaka Hata. "Ultrasonic Diagnosis for Bone Fracture Healing Process." In 2020 IEEE 50th International Symposium on Multiple-Valued Logic (ISMVL). IEEE, 2020. http://dx.doi.org/10.1109/ismvl49045.2020.00-37.

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Kimura, Satoshi, Keisuke Oe, Yohei Kumabe, Tomoaki Fukui, Takahiro Niikura, Ryosuke Kuroda, Naomi Yagi, and Yutaka Hata. "Ultrasonic Diagnosis for Bone Fracture Healing Process." In 2020 IEEE 50th International Symposium on Multiple-Valued Logic (ISMVL). IEEE, 2020. http://dx.doi.org/10.1109/ismvl49045.2020.00-37.

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He, Yiwei, Yuan Ma, Zhe Zhao, and Milin Zhang. "A Biomechanical Monitor For Bone Fracture Healing." In 2023 IEEE Biomedical Circuits and Systems Conference (BioCAS). IEEE, 2023. http://dx.doi.org/10.1109/biocas58349.2023.10388734.

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Bilek, Vlastimil, Lukas Prochazka, Filip Khestl, David Bujdos, and Stanislav Seitl. "Self-healing capacity of differently cured concretes – Fracture characteristic development." In ADVANCES IN FRACTURE AND DAMAGE MECHANICS XX. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0145025.

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Davies, Robert, and Anthony Jefferson. "Micromechanical modelling of self-healing cementitious materials." In 9th International Conference on Fracture Mechanics of Concrete and Concrete Structures. IA-FraMCoS, 2016. http://dx.doi.org/10.21012/fc9.282.

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Chang, Elaine, Cynthia Chang, Alexander Gordon, Eric Vu, Peter Yang, and Jeffery Cardenas. "Osteonexus: A Fracture Healing System for Space Exploration." In Space 2006. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2006. http://dx.doi.org/10.2514/6.2006-7500.

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Kaufman, J. J., A. Chiabrera, N. Hakim, M. Hatem, M. Figueiredo, P. Nasser, S. Lattuga, P. Trent, A. A. Pilla, and R. S. Siffert. "Bone fracture healing assessment using a neural network." In 1990 IJCNN International Joint Conference on Neural Networks. IEEE, 1990. http://dx.doi.org/10.1109/ijcnn.1990.137694.

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Reports on the topic "Fracture healing"

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Akens, Margarete K., and Cari M. Whyne. Photodynamic Therapy Treatment to Enhance Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, June 2013. http://dx.doi.org/10.21236/ada611585.

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Akens, Margarete K., Cari M. Whyne, Brian C. Wilson, Albert J. Yee, and Diane Nam. Photodynamic Therapy Treatment to Enhance Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, October 2012. http://dx.doi.org/10.21236/ada578788.

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Li, Jiliang. Healing of Stress Fracture in an Animal Model. Fort Belvoir, VA: Defense Technical Information Center, September 2004. http://dx.doi.org/10.21236/ada433113.

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Gerstenfeld, Louis C. Assessment of the Genetic Variation in Bone Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada471462.

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Gerstenfeld, Louis C. Assessment of the Genetic Variation in Bone Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada471893.

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Yee, Cristal Sook Ngei. Determining the Role of Sost and Sostdc1 During Fracture Healing. Office of Scientific and Technical Information (OSTI), January 2016. http://dx.doi.org/10.2172/1297645.

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Hoffman, Andrew, Belinda Beck, Gordon Matheson, and Gabrielle Bergman. Do Capacitively Coupled Electric Fields Accelerate Tibial Stress Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, October 2002. http://dx.doi.org/10.21236/ada409629.

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Hoffman, Andrew, Belina Beck, Gordon Matheson, and Gabriella Bergman. Do Capacity Coupled Electric Fields Accelerate Tibial Stress Fracture Healing? Fort Belvoir, VA: Defense Technical Information Center, October 2004. http://dx.doi.org/10.21236/ada429054.

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Hoffman, Andrew, Belinda Beck, Gordon Matheson, and Gabrielle Bergman. Do Capacitively Coupled Electric Fields Accelerate Tibial Stress Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, October 2003. http://dx.doi.org/10.21236/ada419665.

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Hoffman, Andrew R., Belinda Beck, Gordon Matheson, and Gabrielle Bergman. Do Capactively Coupled Electric Fields Accelerate Tibial Stress Fracture Healing. Fort Belvoir, VA: Defense Technical Information Center, December 2005. http://dx.doi.org/10.21236/ada459781.

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