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Academic literature on the topic 'Fr 13'

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Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Fr 13"

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Doshi, Sahil D., Morgan RL Lichtenstein, Melissa Parsons Beauchemin, Rohit R. Raghunathan, Cynthia Law, Melissa Kate Accordino, Jason Dennis Wright, Elena B. Elkin, and Dawn L. Hershman. "Factors associated with failure to receive oral anticancer drugs." Journal of Clinical Oncology 39, no. 28_suppl (October 1, 2021): 41. http://dx.doi.org/10.1200/jco.2020.39.28_suppl.41.

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41 Background: Oral anti-cancer drugs (OACDs) have become increasingly prescribed over the last 10 years and require a significant amount of care coordination. Preliminary administrative database studies have shown that 10-15% of prescriptions are never received by the patient, but the reasons behind this are poorly understood. In this study, we prospectively identified failure to receive (FR) cases in which OACD prescriptions were never received by patients, examined underlying reasons for FR, and assessed clinical and process-related factors associated with FR. Methods: We prospectively collected data on new OACD prescriptions for adult oncology patients at a large, urban academic cancer center from 1/1/2018 to 12/31/2019. We collected patient demographic, clinical, and insurance data, OACD delivery date, and interactions with payers and financial assistance groups. FR was defined as failure to receive a prescribed OACD. Reasons for FR were confirmed by manual chart review and classified into seven categories: clinical deterioration, financial access, provider-driven clinical decision making, patient-directed change, transfer of care, lost to follow up, and other. We calculated the relative proportion of each FR category and used multivariable logistic regression to identify factors associated with FR, including initiation of a prior authorization and drug class. Results: The cohort included 1,080 patients who were prescribed 1,269 new OACDs. Of these prescriptions, 13% (N=163) were categorized as FR. Among the 158 patients with FR, average patient age was 66 years, 55% identified as non-Hispanic white, 61% had any Medicare plan, 11% had Medicaid only, and 25% had commercial insurance. Overall, 18% of FR cases were attributed to clinical deterioration, 13% to financial access, 29% to provider-driven clinical decision making, 17% to patient-directed change, 13% to transfer of care, and 5% were lost to follow up. Univariate analysis showed that FR was less likely in cases where prior authorization was initiated (p < 0.001) and multivariate analysis confirmed this result (OR 0.47 [CI 0.33-0.66], p < 0.001). Conclusions: Though the majority of oncology patients prescribed OACDs received the drug, 13% of patients in our study experienced FR. FR is associated with a lack of prior authorization initiation, which may reflect barriers to access, a change in clinical decision-making, or patient choice. Ultimately, FR is multifactorial and may be appropriate in some cases. More work is needed to determine whether improved access would increase uptake in some patients. [Table: see text]
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Klebanov, Simon, Jeremiah T. Herlihy, and Gregory L. Freeman. "Effect of long-term food restriction on cardiac mechanics." American Journal of Physiology-Heart and Circulatory Physiology 273, no. 5 (November 1, 1997): H2333—H2342. http://dx.doi.org/10.1152/ajpheart.1997.273.5.h2333.

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Food restriction (FR) is the only known intervention capable of increasing mammalian life span. It not only increases longevity, but reduces the incidence of a broad spectrum of age-related pathologies, including cardiomyopathy, and retards the physiological decline associated with aging. Previous work from this laboratory has shown that long-term FR affects the contractile machinery of the heart, shifting the cardiac myosin profile from the fast, V1 isoform to the slow, V3 isoform. The aim of the present study was to determine whether FR also induces changes in cardiac mechanics. Isolated, isovolumically beating hearts were examined from four groups of rats: 1) ad libitum-fed rats killed at 10–13 mo of age, 2) FR rats offered only 60% of the calories consumed by ad libitum-fed rats and killed at the same age, 3) young ad libitum-fed rats having the same heart weights as the FR rats, and 4) ad libitum-fed rats subjected to short-term FR, i.e., for the last 3 wk of life, and also killed at 10–13 mo of age. Both short- and long-term FR profoundly and to approximately the same extent affected cardiac mechanics. Hearts from FR rats developed much higher pressures than hearts from the ad libitum-fed rats under conditions of low-calcium perfusate. This difference disappeared, however, when contractility was enhanced by either calcium or isoproterenol. FR prolonged both contraction and relaxation times. Long-term ad libitum-fed rats (adult, 10–13 mo of age) had a lower isoproterenol sensitivity than the young ad libitum-fed rats (10 wk of age). Both short- and long-term FR restored the sensitivity to isoproterenol. In summary, FR profoundly affects many aspects of cardiac mechanics, enhancing some age-related changes (prolongation of the contraction and relaxation times), attenuating another (increasing the isoproterenol sensitivity), and, finally, inducing some unique changes unrelated to age (increased pressure development under low-calcium perfusate).
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Ahola, Vellamo, and Kari Leinonen. "Responses of Betula pendula, Picea abies, and Pinus sylvestris seeds to red/far-red ratios as affected by moist chilling and germination temperature." Canadian Journal of Forest Research 29, no. 11 (December 1, 1999): 1709–17. http://dx.doi.org/10.1139/x99-128.

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The effect of continuous exposure to various red/far-red ratios (R/FR) on the germination ofBetula pendula Roth, Picea abies (L.) Karst., and Pinus sylvestris L. seeds was studied at four different germination temperatures (10, 13, 16, and 20°C) using both moist-chilled and unchilled seeds. Germination of B. pendula seeds was prevented by low R/FR. In B. pendula the relationship between germination probability and R/FR (log2) at different temperatures was successfully quantified using parallel logistic curves. The relationship between mean germination time (log10) and R/FR (log2) was linear. Moist chilling for 3 weeks reduced but did not eliminate the R/FR response in B. pendula. In Picea abies seeds, low R/FR prevented germination at 10°C but not at 13-20°C. Pinus sylvestris seeds did not respond to low R/FR at the studied temperatures. It appears that B. pendula has evolved a light-sensing mechanism that prevents seed germination in shaded conditions. This mechanism could operate more effectively in autumn than in spring after natural moist chilling during overwintering in soil. Picea abies seeds have also evolved a light-sensing mechanism that regulates germination in cool conditions.
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Crowley, Helen. "Mary McIntosh (13 March 1936–5 January 2013)." Feminist Review 104, no. 1 (July 2013): 146–48. http://dx.doi.org/10.1057/fr.2013.11.

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Zhang, Mengzi, and Erik S. Runkle. "Regulating Flowering and Extension Growth of Poinsettia Using Red and Far-red Light-emitting Diodes for End-of-day Lighting." HortScience 54, no. 2 (February 2019): 323–27. http://dx.doi.org/10.21273/hortsci13630-18.

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Manipulating light quality is a potential alternative method of regulating plant height in the commercial production of ornamental crops. In particular, end-of-day (EOD) lighting with a high red (R; 600–700 nm) to far-red (FR; 700–800 nm) ratio (R:FR) can suppress extension growth, whereas a low R:FR can promote it. We investigated the effects of the R:FR and duration of EOD lighting in regulating extension growth and flowering of two poinsettia cultivars, White Glitter and Marble Star. Plants were grown at 20 °C under 9-hour days with or without EOD lighting provided by two types of light-emitting diode bulbs: R+white+FR (subsequently referred to as R+FR) and FR only. The R:FR ratios were 0.73 and 0.04, respectively, and the photon flux density between 400 and 800 nm was adjusted to 2 to 3 μmol·m−2·s–1 at plant canopy. The six EOD lighting treatments were R+FR or FR for 2 or 4 hours, 2 hours of R+FR followed by 2 hours of FR, and 4 hours of R+FR followed by 2 hours of FR. We also investigated the impact of a 4-hour moderate-intensity (13 μmol·m−2·s–1) EOD FR treatment in the second replication. EOD lighting generally increased poinsettia extension growth, with the greatest promotion under the longest lighting periods. There were no differences in days to first bract color and days to anthesis when the 9-hour day was extended by 2 hours, but flowering was delayed under 4- or 6-hour EOD treatments, except for the 2-hour R+FR + 2-hour FR and 4-hour FR treatments. Four hours of moderate-intensity EOD FR greatly promoted extension growth and delayed or prevented bract coloration in both cultivars. We conclude that EOD lighting promotes extension growth of poinsettia, and specifically, EOD FR at a low intensity (2–3 μmol·m−2·s–1) is not perceived as long-day signal, whereas a higher intensity (13 μmol·m−2·s–1) of FR delays flowering.
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Yakovlieva, M., T. Tacheva, S. Mihaylova, R. Tropcheva, K. Trifonova, A. Toleкova, S. Danova, and T. Vlaykova. "Influence of Lactobacillus brevis 15 and Lactobacillus plantarum 13 on blood glucose and body weight in rats after high-fructose diet." Beneficial Microbes 6, no. 4 (August 2015): 505–12. http://dx.doi.org/10.3920/bm2014.0012.

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In recent years, many authors have investigated the possible antidiabetic effect of lactic acid bacteria. Lactobacillus species constitute a major part of the lactic acid bacteria group and have been found to exhibit beneficial effects on the development of diabetes and its complications. In the current study, we investigated the effects of newly characterised Bulgarian Lactobacillus strains, Lactobacillus brevis 15 and Lactobacillus plantarum 13, on blood glucose levels and body weight of rats fed a fructose-enriched diet. An experiment was conducted over a period of 8 weeks with 24 2-month-old Wistar rats randomly assigned to receive a standard diet (Con, control group), fructose-enriched diet (Fr group), standard diet with probiotics given twice a week (Pro group), and fructose-enriched diet with probiotics given twice a week (Pro+Fr group). At the end of the experimental period, a statistically significant increase in body weight was observed in all experimental groups (P<0.0001). The highest rise was seen in the fructose group (Fr, 169±19 g), followed by the Pro+Fr group (153±15 g), Pro group (149±13 g), and Con group (141±5 g). Moreover, the final blood glucose levels had risen significantly in the groups receiving fructose either without (Fr; P<0.0001) or with lactobacilli (Pro+Fr; P=0.002), while the rise was insignificant in the group of rats given probiotic supplementation only (Pro, P=0.071) and inexistent in the Con group (P=0.999). The highest elevation of blood glucose levels was observed in the Fr group (3.18 mmol/l), followed by the Pro+Fr group (2.00 mmol/l) whereas the Pro group showed the lowest levels (0.60 mmol/l). The results of our study suggest that the newly characterised Bulgarian Lactobacillus strains, L. brevis 15 and L. plantarum 13, could be considered as possible probiotics and might be able to prevent some metabolic disturbances.
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Shirreffs, Susan M., Stuart J. Merson, Susan M. Fraser, and David T. Archer. "The effects of fluid restriction on hydration status and subjective feelings in man." British Journal of Nutrition 91, no. 6 (June 2004): 951–58. http://dx.doi.org/10.1079/bjn20041149.

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Hydration status and the effects of hypohydration have been the topic of much public and scientific debate in recent years. While many physiological responses to hypohydration have been studied extensively, the subjective responses to hypohydration have largely been ignored. The present investigation was designed to investigate the physiological responses and subjective feelings resulting from 13, 24 and 37 h of fluid restriction (FR) and to compare these with a euhydration (EU) trial of the same duration in fifteen healthy volunteers. The volunteers were nine men and six women of mean age 30 (SD 12) years and body mass 71·5 (SD 13·4) kg. Urine and blood samples were collected and subjective feelings recorded on a 100 mm verbally anchored questionnaire at intervals throughout the investigation. In the EU trial the subjects maintained their normal diet. Body mass decreased by 2·7 (SD 0·6) % at 37 h in the FR trial and did not change significantly in the EU trial. Food intake in the FR trial (n 10) provided an estimated water intake of 487 (SD 335) ml and urinary losses (n 15) amounted to 1·37 (SD 0·39) litres. This is in comparison with an estimated water intake of 3168 (SD 1167) ml and a urinary loss of 2·76 (SD 1·11) litres in the EU trial. Plasma osmolality and angiotensin II concentrations increased from 0–37 h with FR. Plasma volume decreased linearly throughout the FR trial amounting to a 6·2 (SD 5·1) % reduction by 37 h. Thirst increased from 0–13 h of FR then did not increase further (P>0·05). The subjects reported feelings of headache during the FR trial and also that their ability to concentrate and their alertness were reduced.
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Tempesta, Stefano Martinelli. "Nota a Saffo, fr. 16, 12-13 V. ("P.Oxy". 1231)." Quaderni Urbinati di Cultura Classica 62, no. 2 (1999): 7. http://dx.doi.org/10.2307/20546583.

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9

Gerrie, Alina S., Cynthia L. Toze, Khaled M. Ramadan, Charles H. Li, Adrian Yee, and Joseph M. Connors. "Fludarabine (F) and Rituximab (R) (FR) as Initial Therapy for Symptomatic Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL): Population-Based Experience Matches Clinical Trials." Blood 114, no. 22 (November 20, 2009): 2363. http://dx.doi.org/10.1182/blood.v114.22.2363.2363.

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Abstract Abstract 2363 Poster Board II-340 Background: Clinical trials report that FR as initial therapy in symptomatic CLL produces an overall response rate of 90% and significantly improves progression-free survival (PFS) and overall survival (OS) compared retrospectively to F alone [Byrd Blood 2003, 2005] and that FCR (F, cyclophosphamide and R) improves response rates and PFS compared to FC alone [Hallek ASH 2008]. FR has been the standard initial therapy for CLL/SLL in British Columbia (BC) (population = 4.2 × 106) since 2004. We wished to determine if, in an unselected community based population, the same results could be achieved with FR therapy as those seen in highly selected clinical trial populations. Patients and Methods: The BC Cancer Agency (BCCA) Lymphoid Cancer Database was searched to identify pts who received FR as initial therapy for CLL/SLL as per BCCA guidelines (F 40mg/m2/day orally D1-5 or 25mg/m2/day IV D1-5 [adjusted for renal function] and R 375mg/m2 IV D1, q 28 days for 4-8 cycles). Pts were excluded if they had more than one hematologic malignancy (n=2). OS was calculated from date of FR to date of death or last follow-up. Treatment-free survival (TFS) was calculated from date of FR to date of next treatment or death from toxicity. Factors present at initiation of treatment were analyzed for impact on outcomes. Results: 98 pts were identified who received FR from 2004-2009 as initial therapy for CLL (83%) or SLL (17%). Median age at FR was 62 y (range, 42 – 86 y). 36% had Rai stage 3 or 4 and 13% had ECOG performance status 2-3. Median lymphocyte count was 30 × 109/L (range 0.6-282 × 109/L) and LDH was elevated in 34% (29/86 with available levels). Nearly half of all pts tested were positive for CD38 (34 of 69 pts, 49%) and ZAP 70 expression (10 of 22 pts, 45%). FISH was performed in 35 pts: 13q deletion, 21 (60%); 11q deletion, 5 (14%); 17p deletion, 10 (29%); trisomy 12, 11 (31%). Most pts (65%) were observed prior to FR for a median of 28 months (range, 3 – 172 mos). Common indications for treatment included symptomatic lymphadenopathy (n=36), cytopenias (n=28), fatigue (n=23), and constitutional symptoms (n=19). Pts underwent a median of 6 cycles of FR (range, 1-8). Treatment was discontinued due to toxicity in 13 pts (13%) (cytopenias, 5; febrile neutropenia, 3; infection, 2; pulmonary disease, 1; ITP, 1; AIHA, 1) and due to progression in 4 pts (4%). Hospitalization during therapy was required in 13 pts (13%) (febrile neutropenia, 5; documented infection, 2; elective splenectomy, 2; pulmonary disease, 2; ITP, 1; rituximab administration, 1). At a median follow up of living pts of 2.4 y, 31 pts (32%) have received additional therapy after FR including CVP in 11 pts (+R, 8); chlorambucil, 7 (+ R, 1; +prednisone, 1); FR, 5; cyclophosphamide, 5 (+prednisone, 3; +vincristine, 1); CHOP, 3 (+R, 2). At time of analysis (June 2009), 86 pts were alive; 14 died, 12 from progressive CLL and 2 from toxicity of FR (severe infection, 1; interstitial lung disease, 1). For the entire 98 pts, the 2 and 4 y OS were 90% and 72%, respectively (median not reached); 2 and 4 y TFS were 69% and 54%, respectively (median 4.0 y). Factors at treatment contributing to OS in univariate analysis included elevated LDH (P=0.004), Hb <110 g/L (P=0.03), and the presence of deletion 17p by FISH (P=0.04) or CD38 expression (>15% of CD19+ cells) by immunophenotyping (P=0.04). TFS was significantly worse in those with Hb <110 g/L (P=0.003), Rai stage 3-4 (P=0.008) or lymphocyte count >150 × 109/L (P=0.0013) while cytogenetic abnormalities and immunophenotyping had no effect on TFS. Age ≥ 60 y (n=60) or age ≥ 70 y (n=26) had no effect on either OS or TFS. Conclusions: In this non-selected community based population of pts with CLL/SLL, including many over 60 y (61%) and 70 y (27%) of age, our results show that initial treatment with FR leads to excellent OS and TFS, consistent with clinical trial results: 2 y OS, this study 90%; FR Byrd [Blood 2005] 93%; FCR Hallek [ASH 2008] 91%; 2 y TFS, this study 69%; FR Byrd, 2 y PFS 67%; FCR Hallek 2 y PFS 77%. FR can be safely and successfully given to community based pts, irrespective of age, for first-line therapy for CLL/SLL with OS and TFS similar to that achieved in clinical trial settings. Disclosures: Connors: Roche Canada: Research Funding.
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Hodin, Theresa L., Tanbir Najrana, and John L. Yates. "Efficient Replication of Epstein-Barr Virus-Derived Plasmids Requires Tethering by EBNA1 to Host Chromosomes." Journal of Virology 87, no. 23 (September 25, 2013): 13020–28. http://dx.doi.org/10.1128/jvi.01606-13.

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The EBNA1 protein of Epstein-Barr virus enables plasmids carryingoriPboth to duplicate and to segregate efficiently in proliferating cells. EBNA1 recruits the origin recognition complex (ORC) to establish a replication origin at one element oforiP, DS (dyadsymmetry); at another element, FR (family ofrepeats), EBNA1 binds to an array of sites from which it tethers plasmids to host chromosomes for mitotic stability. We report experiments leading to the conclusion that tethering by EBNA1 to host chromosomes is also needed within interphase nuclei in order for plasmids to be replicated efficiently fromoriP. The DNA-binding domain of EBNA1, which lacks chromosome-binding ability, was found to support weak, DS-specific replication in HEK293 cells after transient transfection, being 17% as active as wild-type EBNA1. The low efficiency of replication was not due to the failure of the DNA-binding domain to retain plasmids within nuclei, because plasmids were recovered in similar amounts and entirely from the nuclear fraction of these transiently transfected cells. A derivative of EBNA1 with its chromosome-tethering domains replaced by a 22-amino-acid nucleosome-binding domain was fully active in supportingoriPfunctions. The implication is that EBNA1's DNA-binding domain is able to recruit ORC to DS, but either this step or subsequent replication is only efficient if the plasmid is tethered to a host chromosome. Finally, with some cell lines, DS can hardly support even transient plasmid replication without FR. A loss of plasmids lacking FR from nuclei cannot account for this requirement, suggesting that the stronger tethering to chromosomes by FR is needed for plasmid replication within the nuclei of such cells.
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Dissertations / Theses on the topic "Fr 13"

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Mülke, Christoph. "Solons politische Elegien und Iamben (Fr. 1-13, 32-37 West) : Einleitung, Text, Übersetzung, Kommentar /." München : K. G. Saur, 2002. http://catalogue.bnf.fr/ark:/12148/cb39086072k.

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Jaccoud, Sigismond. "Des conditions pathogéniques de l'albuminurie thèse pour le doctorat en médecine, présentée et soutenue le 13 juillet 1860 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1860x121.

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Lediscot, Louis-Pierre. "De l'infanticide Essai médico-légal présenté et soutenu à l'école de médecine de Paris le 30 primaire an 13 /." Paris : BIUM, 2004. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1804x354.

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Collin, François-Théophile. "Considérations sur la nostalgie thèse présentée et soutenue à la Faculté de médecine de Paris le 13 décembre 1832 /." Paris : BIUM, 2004. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1832x271.

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Guiter, Chrystelle Leroy Karen Castellano Flavia. "Étude de la voie de signalisation IL-4/IL-13 dans les lymphomes B primitifs du médiastin." S. l. : S. n, 2008. http://doxa.scd.univ-paris12.fr:8080/theses-npd/th0494715.htm.

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Guyon, Jean-Casimir-Félix. "Étude sur les cavités de l'utérus à l'état de vacuité thèse présentée et soutenue à la Faculté de médecine de Paris le 13 mars 1858 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1858x048.

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Pourquery, de Boisserin Juliette. "L'énergie chevaleresque : étude de la matière textuelle et iconographique du manuscrit BnF fr.340 (compilation de Rusticien de Pise et Guiron le courtois)." Rennes 2, 2009. http://tel.archives-ouvertes.fr/tel-00458206/fr/.

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Guiron le courtois, vaste roman de chevalerie en prose composé du Roman de Meliadus et du Roman de Guiron a été copié, remanié, compilé dans de nombreux manuscrits depuis sa création, entre 1235-1240, jusqu’à la fin du Moyen Âge. Sa matière ouverte à toutes les continuations en fait une œuvre aux contours flous. Le manuscrit BnF fr. 340 (fin XIVe-début XVe siècle), associant le Roman de Meliadus et la Compilation de Rusticien de Pise, forme un ensemble où se dessine la chevalerie errante des pères des grands héros arthuriens, animée par la violence des combats, l’abondance du sang versé, mais aussi par la joie des rencontres et de la parole échangée. C’est cette communauté vivante que cette thèse entreprend d’analyser, à travers l’exploration conjointe du texte et de l’image du manuscrit BnF fr. 340, dont l’analyse iconographique sera ouverte à d’autres programmes de manuscrits de la même période
Guiron le courtois—a vast chivalric novel written in prose and composed of the Roman de Meliadus and of the Roman de Guiron—was copied, redrafted, compiled in various manuscripts since its creation spanning from 1235-1240 to the end of the Middle Ages. Its material allows all kinds of continuations which makes it a work with blurred outlines. The manuscript BnF fr. 340 (End of 14th-Beginning 15th Century) associates the Roman de Meliadus and the Compilation of Rusticien de Pise; it forms a whole in which can be seen wandering knights, namely the fathers of the great Arthurian heroes driven by violent fights and a desire to shed blood abundantly, but also by merry encounters and word exchanges. This thesis ends at analysing this lively community through the exploration of both text and imagery in the manuscript BnF Fr 340; this iconographic analysis leads to the study of new programs of manuscripts dating back to the same period
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Clemenceau, Georges. "De la génération des éléments anatomiques thèse pour le doctorat en médecine présentée et soutenue le 13 mai 1865 [à la Faculté de médecine de Paris] /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1865x092.

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Marshall-Anderson, Mary Adamson. "Du rétrécissement mitral : sa fréquence plus grande chez la femme que chez l'homme thèse pour le doctorat en médecine présentée et soutenue le 13 décembre 1879 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1879x539.

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Renard, Delphine Grimprel Emmanuel. "Méningite à Haemophilus influenzae de type b chez l'enfant étude de 13 cas, enfants ayant reçu au moins 1 injection du vaccin anti-Haemophilus influenzae b, entre janvier 2001 et juin 2005 /." Créteil : Université de Paris-Val-de-Marne, 2006. http://doxa.scd.univ-paris12.fr:80/theses/th0237246.pdf.

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Books on the topic "Fr 13"

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Das Andachtsbuch der Marie de Gavre: Paris, Bibliothèque nationale, Ms. nouv. acq. fr. 16251 : Buchmalerei in der Diözese Cambrai im letzten Viertel des 13. Jahrhunderts. Wiesbaden: L. Reichert, 1997.

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Muelke, Christoph. Solons politische Elegien und Iamben (fr. 1-13, 32-37 W.) (BZA 177). K.G. Saur (An Impint of Walter de Gruyter), 2002.

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Mascitelli, Cesare. La Geste Francor nel cod. marc. V13. Trascrizione diplomatico-interpretativa del manoscritto Venezia, Biblioteca Nazionale Marciana, Fr. Z 13 (=256). Éditions de Linguistique et de Philologie (ELiPhi), 2021. http://dx.doi.org/10.46277/slir.2021.001.

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La presente trascrizione diplomatico-interpretativa del ms. Venezia, Biblioteca Nazionale Marciana, Fr. Z 13 (=256) è pensata a complemento della monografia La Geste Francor nel cod. marc. V13. Stile, tradizione, lingua. Caratterizzata da una piena aderenza alla mise en page del codice marciano, essa si configura come strumento di agile consultazione per il lettore, che può rintracciarvi i fenomeni più salienti della scripta di cui si dà conto nella monografia. La fedeltà della trascrizione alla facies graphica del manoscritto – resa più intelligibile dallo scioglimento delle abbreviazioni e dalla separazione delle parole – permette inoltre di seguire gli interventi di correzione effettuati probabilmente dal copista stesso.
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Gestion de l'Enseignement Supérieur, Volume 13 Numéro 1. OECD, 2001. http://dx.doi.org/10.1787/hemp-v13-1-fr.

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Gestion de l'enseignement supérieur, Volume 13 Numéro 2. OECD, 2001. http://dx.doi.org/10.1787/hemp-v13-2-fr.

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Gestion de l'enseignement supérieur, Volume 13 Numéro 3. OECD, 2001. http://dx.doi.org/10.1787/hemp-v13-3-fr.

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Documentation des prix de transfert et déclaration pays par pays, Action 13 - Rapport final 2015. OECD, 2015. http://dx.doi.org/10.1787/9789264248502-fr.

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Almeida, Joseph A. Solon’s Reception of Hesiod’s Works and Days. Edited by Alexander C. Loney and Stephen Scully. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780190209032.013.41.

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This chapter presents observations about the relationship between the poetry of Hesiod and of Solon (Works and Days 213–326 and Solon frr. 4 and 13). In the first half of fr. 4 Solon, through a series of allusions, incorporates into his poem Hesiod’s authority on dikē to validate condemnation of injustice in his own city, and in the second half of the poem he turns the Hesiodic pessimism of this injustice into an optimistic hope for his city’s just future. In fr. 13 Solon expands Hesiod’s notion of Zeus as the punisher of injustice to create a pessimistic view of human life darker than Hesiod’s own. A final discussion of the scholarly division on the question of whether dikē in Solon is essentially Hesiodic or something new in Greek thought rounds out the observations on the relation between the poets and confirms Solon’s dependence on Hesiod.
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Germany), Martin-Gropius-Bau (Berlin, Kunst- und Ausstellungshalle der Bundesrepublik Deutschland., and Staatliche Museen zu Berlin--Preussischer Kulturbesitz. Antikensammlung., eds. Die griechische Klassik: Idee oder Wirklichkeit : eine Ausstellung im Martin-Gropius-Bau, Berlin, 1. März-2. Juni 2002 und in der Kunst- und Ausstellungshalle der Bundesrepublik Deutschland, Bonn, 5. Juli-6. Oktober 2002 [i.e. 12. Juli-13. Oktober 2002]. Mainz: Zabern, 2002.

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Bulletin de Droit Nucléaire - Roumanie : Loi sur la responsabilité civile des dommages nucléaires (3 décembre 2001) Ukraine : Loi sur la responsabilité civile en matière de dommage nucléaire et les garanties financières y afférentes (13 décembre 2001). Éditions OCDE, 2002. http://dx.doi.org/10.1787/nuclear_law-v2002-sup1-fr.

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Book chapters on the topic "Fr 13"

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"Article 13 Gains en capital." In Modèle de Convention fiscale concernant le revenu et la fortune (Version complète). OECD, 2019. http://dx.doi.org/10.1787/09a01e5b-fr.

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"Article 13 Gains en capital." In Modèle de Convention fiscale concernant le revenu et la fortune (Version complète). OECD, 2016. http://dx.doi.org/10.1787/9789264239142-16-fr.

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"Commentaires sur l'article 13." In Modèle de Convention fiscale concernant le revenu et la fortune : Version abrégée 2017, 317–30. OECD, 2018. http://dx.doi.org/10.1787/mtc_cond-2017-16-fr.

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"R(13). Attribution de revenus aux établissements stables." In Modèle de Convention fiscale concernant le revenu et la fortune (Version complète). OECD, 2019. http://dx.doi.org/10.1787/380f5735-fr.

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Davey, Kenneth R., Olivier Lavigne, and James Y. G. Chu. "The Probabilistic Fr 13 Risk Framework—A Critical Review." In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-12-409547-2.14411-7.

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"Commentaires sur l’article 13 Concernant l’imposition des gains en capital." In Modèle de Convention fiscale concernant le revenu et la fortune (Version complète). OECD, 2019. http://dx.doi.org/10.1787/51e17e74-fr.

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"R(13). Attribution de revenus aux établissements stables." In Modèle de Convention fiscale concernant le revenu et la fortune (Version complète). OECD, 2016. http://dx.doi.org/10.1787/9789264239142-106-fr.

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"ANNEXE A. Caractéristiques des pays membres du CAD en matière d'aide extérieure." In La gestion de l'aide, 123–92. OECD, 2011. http://dx.doi.org/10.1787/9789264060234-13-fr.

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"Références." In Le commerce international, 212–23. OECD, 2009. http://dx.doi.org/10.1787/9789264060289-13-fr.

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"L'emploi dans l'administration générale et les entreprises publiques." In Panorama des administrations publiques, 72–73. OECD, 2009. http://dx.doi.org/10.1787/9789264061675-13-fr.

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Conference papers on the topic "Fr 13"

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Estrada, Daniel, Valentina Perea Torres, and Juan Manuel López López. "FRECUENCIA RESPIRATORIA EN IMÁGENES." In Mujeres en ingeniería: empoderamiento, liderazgo y compromiso. Asociacion Colombiana de Facultades de Ingeniería - ACOFI, 2021. http://dx.doi.org/10.26507/ponencia.1757.

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La frecuencia respiratoria (FR) es la cantidad de respiraciones por minuto que realiza un ser vivo y está regulada por el sistema nervioso y algunas otras características fisiológicas o patológicas. La FR se puede extraer por medio de Fotopletismografía de imagen (IPPG), la cual es una técnica que consiste en extraer diferentes variables fisiológicas del video de una persona, de manera remota y sin contacto. Para esta investigación se decidió estudiar la FR debido a su importancia en el contexto clínico, ya que refleja algunas funciones esenciales del cuerpo. Puede ser de utilidad, por ejemplo, para detectar enfermedades respiratorias y/o cardiacas. En este proyecto, se estudiaron un total de 13 participantes, cuyas edades variaban entre los 18 y 50 años. Para la adquisición de los videos, se utilizaron las cámaras con las que contaba cada participante, como la cámara integrada de un computador o la cámara de un celular. El ejercicio consistía en la grabación de un video por cada participante de alrededor de 3 minutos, donde se le indicaba cómo respirar para así controlar su FR y después compararla con los resultados. La medición de la FR se hizo por medio de la aplicación “Paced Breathing” ya usada en investigaciones anteriores. Para la extracción de la señal se realizó primero la localización de una región de interés (ROI) en el rostro, con el algoritmo de Viola-Jones, para luego aplicar una etapa de remoción de artefactos. A través de técnicas de procesamiento de imágenes y procesamiento estadístico de señales multivariables se pudo extraer la FR de cada sujeto con error promedio de3.3% a través de análisis con transformada Wavelet y 2.65% con análisis de Fourier. Se utilizaron herramientas de preprocesamiento como filtros frecuenciales, remoción de tendencias lineales y filtros de media móvil. Los métodos propuestos en este trabajo son novedosos y presentan una alternativa para la extracción de diferentes variables fisiológicas. Las condiciones de grabación de los participantes no están bajo muchas restricciones, por lo que podría ser utilizado en varios campos de la salud sin necesidad de condiciones exigentes. Además, muestra un desempeño similar al estado del arte y provee una forma no invasiva para la medición de una variable fisiológica de importancia clínica y de investigación.
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Copeland, D. Scott, M. Kaysar Rahim, Jeffrey C. Suhling, Guoyun Tian, Pradeep Lall, Richard C. Jaeger, and Kris Vasoya. "High Reliability Flip Chip Using Low CTE Laminate Substrates." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-82662.

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In this work, we report on our efforts to develop high reliability flip chip on laminate assemblies for deployment in harsh thermal cycling environments characteristic of ground and aerospace vehicles (e.g. −55 to 150 °C). Reliability enhancement has been achieved through the use of a novel low expansion, high stiffness, and relatively low cost laminate substrate material that virtually eliminates CTE mismatches between the silicon die and top layer PCB interconnect. The utilized laminate features a sandwich construction that contains standard FR-406 outer layers surrounding a low expansion high thermal conductivity carbon fiber-reinforced composite core (STABLCOR®). Through both experimental testing and modeling, we have demonstrated that robust flip chip assemblies can be produced that illustrate ultra-high solder joint reliability during thermal cycling and extremely low die stresses. Liquid to liquid thermal shock testing has been performed on test assemblies incorporating daisy chain test die, and piezoresistive test chips have been used to characterize temperature dependent die stresses. In both sets of experiments, results obtained using the hybrid PCB laminate with FR-406 outer layers and carbon fiber core have been compared to those obtained with more traditional glass-epoxy laminate substrates including FR-406 and NELCO 4000-13. Nonlinear finite element modeling results for the low expansion flip chip on laminate assemblies have been correlated with the experimental data. Unconstrained thermal expansion measurements have also been performed on the hybrid laminate materials using strain gages to demonstrate their low CTE characteristics. Other experimental testing has demonstrated that the new laminate successfully passes toxicity, flammability, and vacuum stability testing as required for pressurized and un-pressurized space applications.
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Hayati, Hamideh, and Yu Feng. "A Precise Scale-Up Method to Predict Particle Delivered Dose in a Human Respiratory System Using Rat Deposition Data: An In Silico Study." In 2020 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/dmd2020-9060.

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Abstract As surrogates to human beings, rats are used occasionally to study the therapeutic impact of inhaled pulmonary drug particles in microscale. To speculate human responses from rat studies, scale-up factors are widely used to extrapolate particle lung deposition from rat to human. However, available scale-up methods are highly simplified and not accurate, because they directly use the human-to-rat ratios of body weights (RBW) or lung surface areas (RSA) as the scale-up factor. To find a precise scale-up strategy, an experimentally validated Computational Fluid-Particle Dynamics (CFPD) was employed to simulate the transport and deposition of microparticles in both human and rate respiratory systems, which encompasses the pulmonary routes from mouth/nose to airways up to Generation 17 (G17) for human and G23 for the rat. Microparticles with the same range of Stk/Fr were injected into both models with the airflow at resting conditions. Numerical results indicate that particles (with the size ranging from 1 to 13 μm for humans and 0.6 to 6 μm for rat) have similar deposition pattern (DP) and deposition fraction (DF) in both models, which are resulted from both inertial impaction and gravitational sedimentation effects. A novel correlation is proposed to predict DFs in both human and rat respiratory systems as a function of the ratio of Stokes number to Froude number (Stk/Fr). Using the correlation as the novel scale-up tool, inter-species extrapolations can be precisely done on predicting particle depositions in human respiratory systems based on the deposition data in rats obtained from animal studies.
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Anschutz, Don, Pat Wildt, Mark McGill, Terry Lowrey, and Kevin Contreras. "Understanding the Shear History of Various Loadings of Friction Reducers and the Associated Impact on the Fluid's Stability, Pipe Friction Reduction, and Effect on Proppant Transport and Deposition in Both Fresh Water and Brine Base Fluid." In SPE Hydraulic Fracturing Technology Conference and Exhibition. SPE, 2023. http://dx.doi.org/10.2118/212324-ms.

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Abstract The industry is constantly looking for ways to increase completions efficiency, increase well production, and reduce cost. Unconventional completions, on average, use around 4.5 million gallons of water carrying up to 10 million pounds of frac sand. Volumes vary greatly, from under 1 million gallons of water carrying a couple million pounds of frac sand to greater than 10 million gallons of water carrying up to 20 million pounds of frac sand. Changes in the loading of additives can greatly impact the completion costs. Understanding the advantages, or disadvantages, of any changes made to the frac design can help with efficiency and costs, if implemented correctly. The research in this paper highlights how shear stress, proppant transport, and the deposition profile change based on various loadings of commonly used Friction Reducer (FR) mixed in fresh water and brine water. A 1,500-foot, 0.62-inch internal diameter flow loop is utilized to develop a shear history based on a shear rate equivalent of 100 barrels per minute (BPM) down 11,000 feet of 4.5-inch internal diameter (ID) casing/pipe. FR and High Viscosity Friction Reducers (HVFR) are evaluated at 0.75, 1.5, 3.0 and 5.0 gallons per thousand (gpt) loadings in fresh water and brine as well as guar with a loading of 5.0 gpt in brine (effective polymer loading 20 lbs./1000 gals). Pre-shear and post-shear viscosity readings are recorded for each gel concentration. The shear conditioned fluid is then utilized to construct the test slurry for the subsequent transport/deposition test. The test slurry is injected into a large slot flow apparatus (10′H × 20′L), with a transverse fracture configuration (top-middle-bottom injection points along the vertical centerline) with an average 0.375-inch width tortuous slot flow path. A typical test entails approximately 750 lbs. of proppant, comprised of 80% by weight of 100 mesh proppant 1.5 pounds of proppant added per gallon (PPA) and 20% by weight of 40/70 mesh proppant at 1.5 PPA. Slurry test pump rate target is 13 gallons per minute (gpm) to simulate the lower shear rate in a far-field fracture environment. Fluid viscosity measurements are recorded post blender and post slot flow apparatus. A deposition profile is generated for each FR loading and job design. The data are compiled to demonstrate the effects of shear history on the carrier fluid viscosity, as well as to document transport and deposition behavior based on the various loadings of the different friction reducers and pump schedules.
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Newhouse, M. T., and P. H. Goldman. "SOBIstat-F (S-F), a Unique, Metered Dose Inhaler (MDI)-Based, Exhalation-Filtered Cardiopulmonary Resuscitation O2 Mask (CPROM) That Very Rapidly Initiates O2 and Bronchodilator Aerosol Therapy (Tx) While Protecting First Responders (FR) from COVID-19." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2676.

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Fernandes, Priscilla Neves, JORGE ANTONIO FILHO, ALINE DE AMORIM DA SILVA, FERNANDA WERNECK DE MATTOS MOURA, and RUBIA CANTARIN DE SOUZA. "RELATO DE CASO: LEPTOSPIROSE GRAVE SEM ICTERÍCIA." In II Congresso Nacional de Microbiologia Clínica On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/ii-conamic/02.

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Introdução: A leptospirose é uma doença infecciosa febril de início abrupto, cujo espectro clínico pode variar desde um processo inaparente, até as formas graves. Objetivo: Enfatizar sobre importância do médico em suspeitar de leptospirose, mesmo sem a presença de icterícia. Material e métodos: Foi realizado a coleta de dados de um paciente atendido na Unidade de Pronto Atendimento de Sepetiba, em maio de 2017. Resultados: Paciente, J.S.S, masculino, 38 anos, trabalha como gari há 13 anos, dá entrada relatando que há 03 dias iniciou quadro de febre aferida (38,5 oC), mialgia, lombalgia e cefaleia de início súbito, há 1 dia vem apresentando tosse seca e dispneia aos médios esforços, evoluindo com um quadro de tosse com expectoração hemoptoicas e piora progressiva da dispneia. Ao exame: acordado, confuso, obedecendo aos comandos, taquidispneico com cianose de extremidades (FR 40 irpm e SatO2 85%), taquicárdico (FC 130 bpm), hipotenso (PA 80 x 50 mmhg), desidratado +/+4, hipocorado (++/4+), anictérico, febril (39 oC). Apresenta murmúrio vesicular universalmente audível com presença de crepitação na base esquerda. Impressões diagnósticas: IRA / H1N1, Dengue hemorrágica e Leptospirose. Foi encaminhado imediatamente para sala vermelha, para cuidados intensivos. Exame laboratorial demostrou hematócrito: 28% com hemoglobina de 10 g/l, leucocitose com neutrofilia e desvio à esquerda, plaquetas 80.000. Bilirrubina total: 2,1 mg/dL; bilirrubina direta: 0,4 mg/dL; Gasometria arterial: alcalose respiratória; Radiografia de tórax apresenta condensação à esquerda. Após 3 horas de internação o paciente apresentou piora do quadro respiratório, evoluindo com síndrome da angústia respiratória aguda, sendo realizado intubação orotraqueal com presença de hemorragia pulmonar maciça, logo em seguida evolui para parada cardiorrespiratória sem reversão e óbito. Após 48 horas foi confirmado sorologia para leptospirose. Conclusão: É importante observar que manifestações graves da leptospirose, como hemorragia pulmonar, podem ocorrer em pacientes anictéricos, portanto, não se deve basear apenas na presença de icterícia para identificar pacientes com leptospirose ou com risco de complicações graves da doença, aumentando as chances de letalidade, pois os casos com comprometimento pulmonar podem evoluir para insuficiência respiratória aguda, hemorragia maciça ou síndrome de angústia respiratória e muitas vezes, esse quadro precede o quadro de icterícia.
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Colon, Carlos J., and Tim Merrigan. "Roof Integrated Solar Absorber: The Measured Performance of “Invisible” Solar Collectors." In ASME 2001 Solar Engineering: International Solar Energy Conference (FORUM 2001: Solar Energy — The Power to Choose). American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/sed2001-120.

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Abstract The Florida Solar Energy Center (FSEC), with the support of the National Renewable Energy Laboratory (NREL), has investigated the thermal performance of solar absorbers which are an integral yet indistinguishable part of a building’s roof. The first roof-integrated solar absorber (RISA) system was retrofitted into FSEC’S Flexible Roof Facility in Cocoa, Florida in September 1998. This “proof-of-concept” system uses the asphalt shingle roof surface and the plywood decking under the shingles as an unglazed solar absorber. The absorbed solar heat is then transferred to water that is circulated from a storage tank through polymer tubing attached to the underside of the roof decking. Data collected on this direct 3.9 m2 (42 ft2) solar system for a period of 12 months indicates that it was able to provide an average of 3.4 kWh per day of hot water energy to the storage tank under a 242 liters (64 gal) per day load. The RISA system’s average annual solar conversion efficiency was also determined to be 8 percent, with daily efficiencies reaching a maximum of 13 percent. In addition, a thermal performance equation has been determined to characterize the Phase 1 RISA system’s year-long efficiency under various ambient temperature, insolation, and wind speed conditions. As a follow-on to the proof-of-concept phase, two prototypes of approximately 4.5 m2 (48 ft2) surface area were constructed and submitted for FSEC thermal performance testing. These Phase 2 RISA prototypes differ in both roof construction and the position of the polymer tubing. One prototype is similar to the “proof-of-concept” RISA system as it employs an asphalt shingle roof surface and has the tubing mounted on the underside of the plywood decking. The second RISA prototype uses metal roofing panels over a plywood substrate and places the polymer tubing between the plywood decking and the metal roofing. Both prototypes were tested according to ASHRAE Standard 93 for determining the thermal performance of solar collectors. From performance data measured both outdoors and indoors using a solar Simulator, FR(ταe)’s were determined to be approximately 18% and 33% for the asphalt shingle and metal roof RISA prototypes, respectively. In addition, the coefficients of linear and second-order efficiency equations were also determined at various wind speeds. Finally, an FSEC thermal performance rating was calculated at the low and intermediate temperature levels. In summary, this paper is a first look at the thermal performance results for these “invisible” solar absorbers that use the actual roof surface of a building for solar heat collection.
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