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Journal articles on the topic 'Forensic genetics – Technique'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Decorte, R., and J. J. Cassiman. "Forensic medicine and the polymerase chain reaction technique." Journal of Medical Genetics 30, no. 8 (August 1, 1993): 625–33. http://dx.doi.org/10.1136/jmg.30.8.625.

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2

González-Jorge, Higinio, Iván Puente, Pablo Eguía, and Pedro Arias. "Single-Image Rectification Technique in Forensic Science." Journal of Forensic Sciences 58, no. 2 (February 20, 2013): 459–64. http://dx.doi.org/10.1111/1556-4029.12068.

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3

Ihms, Elihu C., and Dennis W. Brinkman. "Thermogravimetric Analysis as a Polymer Identification Technique in Forensic Applications." Journal of Forensic Sciences 49, no. 3 (2004): 1–6. http://dx.doi.org/10.1520/jfs2003252.

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4

Decorte, R., and J. J. Cassiman. "Forensic medicine and the polymerase chain reaction technique." Journal of Clinical Forensic Medicine 1, no. 1 (June 1994): 51. http://dx.doi.org/10.1016/1353-1131(94)90066-3.

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5

Hedman, Johannes, Yasmine Akel, Linda Jansson, Ronny Hedell, Nanny Wallmark, Christina Forsberg, and Ricky Ansell. "Enhanced forensic DNA recovery with appropriate swabs and optimized swabbing technique." Forensic Science International: Genetics 53 (July 2021): 102491. http://dx.doi.org/10.1016/j.fsigen.2021.102491.

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6

Biwasaka, Hitoshi, Kiyoshi Saigusa, and Yasuhiro Aoki. "The Applicability of Holography in Forensic Identification: A Fusion of the Traditional Optical Technique and Digital Technique." Journal of Forensic Sciences 50, no. 2 (2005): 1–7. http://dx.doi.org/10.1520/jfs2004333.

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7

Mallett, Xanthé, and Martin P. Evison. "Forensic Facial Comparison: Issues of Admissibility in the Development of Novel Analytical Technique." Journal of Forensic Sciences 58, no. 4 (May 29, 2013): 859–65. http://dx.doi.org/10.1111/1556-4029.12127.

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8

Horton, Benjamin P., Steve Boreham, and Caroline Hillier. "The Development and Application of a Diatom-Based Quantitative Reconstruction Technique in Forensic Science." Journal of Forensic Sciences 51, no. 3 (May 2006): 643–50. http://dx.doi.org/10.1111/j.1556-4029.2006.00120.x.

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9

Acharya, Ashith B. "Forensic Dental Age Estimation by Measuring Root Dentin Translucency Area Using a New Digital Technique." Journal of Forensic Sciences 59, no. 3 (March 7, 2014): 763–68. http://dx.doi.org/10.1111/1556-4029.12385.

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10

Andreola, Salvatore, Guendalina Gentile, Alessio Battistini, Cristina Cattaneo, and Riccardo Zoja. "Forensic Applications of Sodium Rhodizonate and Hydrochloric Acid: A New Histological Technique for Detection of Gunshot Residues." Journal of Forensic Sciences 56, no. 3 (February 3, 2011): 771–74. http://dx.doi.org/10.1111/j.1556-4029.2010.01689.x.

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Chang, Kah Haw, Chong Hooi Yew, and Ahmad Fahmi Lim Abdullah. "Optimization of Headspace Solid-Phase Microextraction Technique for Extraction of Volatile Smokeless Powder Compounds in Forensic Applications." Journal of Forensic Sciences 59, no. 4 (February 24, 2014): 1100–1108. http://dx.doi.org/10.1111/1556-4029.12440.

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12

Love, Jennifer C., and Luis A. Sanchez. "Recognition of Skeletal Fractures in Infants: An Autopsy Technique." Journal of Forensic Sciences 54, no. 6 (November 2009): 1443–46. http://dx.doi.org/10.1111/j.1556-4029.2009.01148.x.

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13

Hallerman, E. M. "Applications and limitations of DNA barcoding in Environmental Biology." Journal of Environmental Biology 42, no. 1 (January 30, 2021): 1–13. http://dx.doi.org/10.22438/jeb/42/1/mrn-1710.

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Species identification is often difficult, especially for early life-history stages, poorly known species within diverse taxa, and microbes. Molecular genetics has contributed the technique of DNA barcoding, offering a low-tech, potentially high-impact tool for identification of species. After briefly describing a range of applications, this review focus on its use for identification of larval fishes. Molecular identification of larval fishes would increase knowledge of larval fish ecology, providing insights into reproductive ecology and population dynamics, and contribute to identification and protection of critical habitat. Other applications of environmental interest include identification of species from fecal starting material and forensic investigation. Limiting application of DNA barcoding is the environmental community's unfamiliarity withthe technique and limited development of DNA sequence archives for some taxa.

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14

Archer, Emily, Heather Allen, Andy Hopwood, and Diane Rowlands. "Validation of a dual cycle ethylene oxide treatment technique to remove DNA from consumables used in forensic laboratories." Forensic Science International: Genetics 4, no. 4 (July 2010): 239–43. http://dx.doi.org/10.1016/j.fsigen.2009.10.004.

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15

Walsh, Graham A., Osman T. Inal, and Van D. Romero. "A Potential Metallographic Technique for the Investigation of Pipe Bombings." Journal of Forensic Sciences 48, no. 5 (September 1, 2003): 2002212. http://dx.doi.org/10.1520/jfs2002212.

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16

Ullrich, Herbert, and Carl N. Stephan. "On Gerasimov’s Plastic Facial Reconstruction Technique: New Insights to Facilitate Repeatability*." Journal of Forensic Sciences 56, no. 2 (January 6, 2011): 470–74. http://dx.doi.org/10.1111/j.1556-4029.2010.01672.x.

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17

de Koeijer, Jan A., Charles E. H. Berger, Wendy Glas, and Henk T. Madhuizen. "Gelatine Lifting, a Novel Technique for the Examination of Indented Writing*." Journal of Forensic Sciences 51, no. 4 (July 2006): 908–14. http://dx.doi.org/10.1111/j.1556-4029.2006.00158.x.

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18

Smith, Shelley L., and Gaylord S. Throckmorton. "A New Technique for Three-Dimensional Ultrasound Scanning of Facial Tissues." Journal of Forensic Sciences 49, no. 3 (2004): 1–7. http://dx.doi.org/10.1520/jfs2003203.

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19

Kowalczyk, Marek, Ewelina Zawadzka, Dariusz Szewczuk, Magdalena Gryzińska, and Andrzej Jakubczak. "Molecular markers used in forensic genetics." Medicine, Science and the Law 58, no. 4 (September 30, 2018): 201–9. http://dx.doi.org/10.1177/0025802418803852.

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Forensic genetics is a field that has become subject to increasing interest in recent years. Both the technology and the markers used for forensic purposes have changed since the 1980s. The minisatellite sequences used in the famous Pitchfork case introduced genetics to the forensic sciences. Minisatellite sequences have now been replaced by more sensitive microsatellite markers, which have become the basis for the creation of genetic profile databases. Modern molecular methods also exploit single nucleotide polymorphisms, which are often the only way to identify degraded DNA samples. The same type of variation is taken into consideration in attempting to establish the ethnicity of a perpetrator and to determine phenotypic traits such as the eye or hair colour of the individual who is the source of the genetic material. This paper contains a review of the techniques and molecular markers used in human and animal forensic genetics, and also presents the potential trends in forensic genetics such as phenotyping.

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20

Oliveira, Pablo Viana, Francine Alves Nogueira de Almeida, Magda Delorence Lugon, Karolinni Bianchi Britto, Janyra Oliveira-Costa, Alexandre Rosa Santos, and Greiciane Gaburro Paneto. "Using high-resolution melting to identify Calliphoridae (blowflies) species from Brazil." PeerJ 8 (November 30, 2020): e9680. http://dx.doi.org/10.7717/peerj.9680.

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Forensic entomology is the study of insects and other arthropods used in the solution of crimes. Most of entomological evidences strongly depend on accurate species identification. Therefore, new methods are being developed due to difficulties in morphological identification, including molecular methods such as High-Resolution Melting. In this study, we reported a new HRM primer set to identify forensically important Calliphoridae (blowflies) from Brazil. For such purpose, Calliphoridae species of forensic importance in Brazil were listed and confirmed by specialists. Mitochondrial COI sequences of those species were downloaded from databases and aligned, and polymorphic variations were selected for distinction between species. Based on it, HRM primers were designed. Forty-three fly samples representing six species were tested in the HRM assay. All samples had the COI gene sequenced to validate the result. Identifying and differentiating the six species proposed using a combination of two amplicons was possible. The protocol was effective even for old insect specimens, collected and preserved dried for more than ten years, unlike the DNA sequencing technique that failed for those samples. The HRM technique proved to be an alternative tool to DNA sequencing, with advantage of amplifying degraded samples and being fast and cheaper than the sequencing technique.

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21

Fox, Sherry C., Constantine Eliopoulos, Ioanna Moutafi, and Sotiris K. Manolis. "A Simple Technique for Imaging the Human Skeleton Using a Flatbed Scanner*." Journal of Forensic Sciences 56 (October 22, 2010): S154—S157. http://dx.doi.org/10.1111/j.1556-4029.2010.01596.x.

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22

Kleinberg, Krista F., Peter Vanezis, and A. Mike Burton. "Failure of Anthropometry as a Facial Identification Technique Using High-Quality Photographs." Journal of Forensic Sciences 52, no. 4 (July 2007): 779–83. http://dx.doi.org/10.1111/j.1556-4029.2007.00458.x.

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23

Mandoreba, Talia Y., Karen J. Cloete, Roya Minnis‐Ndimba, and Olga L. Kupika. "A Novel Application of a Cryosectioning Technique to Aid Scat Hair Microanalysis." Journal of Forensic Sciences 64, no. 4 (December 4, 2018): 1181–86. http://dx.doi.org/10.1111/1556-4029.13976.

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24

Shiroma, Calvin Y., Christopher G. Fielding, John A. Lewis Jr., Mark R. Gleisner, and Kenneth N. Dunn. "A Minimally Destructive Technique for Sampling Dentin Powder for Mitochondrial DNA Testing." Journal of Forensic Sciences 49, no. 4 (2004): 1–5. http://dx.doi.org/10.1520/jfs2003432.

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25

Herbst, Jonathon, Wayne Stanley, and Roger W. Byard. "Autopsy Reenactment - A Useful Technique in the Evaluation of Adhesive Tape Asphyxia." Journal of Forensic Sciences 59, no. 3 (February 6, 2014): 841–43. http://dx.doi.org/10.1111/1556-4029.12378.

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26

Aland, Rachel Claire, Alan Piper, and Edward Gosden. "Development and Validation of a Technique for Casting Anatomical Features and Toolmarks." Journal of Forensic Sciences 61, no. 6 (September 21, 2016): 1604–9. http://dx.doi.org/10.1111/1556-4029.13198.

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27

Li, Biao, Guo liang Ouyang, and Peng nan Zhao. "Preliminary Study on Determining the Sequence of Intersecting Lines by Fluorescence Technique." Journal of Forensic Sciences 63, no. 2 (June 6, 2017): 577–82. http://dx.doi.org/10.1111/1556-4029.13572.

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28

Smith, Lindsay A. "The missing, the martyred and the disappeared: Global networks, technical intensification and the end of human rights genetics." Social Studies of Science 47, no. 3 (December 29, 2016): 398–416. http://dx.doi.org/10.1177/0306312716678489.

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In 1984, a group of Argentine students, trained by US academics, formed the Argentine Forensic Anthropology Team to apply the latest scientific techniques to the excavation of mass graves and identification of the dead, and to work toward transitional justice. This inaugurated a new era in global forensic science, as groups of scientists in the Global South worked outside of and often against local governments to document war crimes in post-conflict settings. After 2001, however, with the inauguration of the war on terror following the September 11th attacks on the World Trade Center in New York, global forensic science was again remade through US and European investment to increase preparedness in the face of potential terrorist attacks. In this paper, I trace this shift from human rights to humanitarian forensics through a focus on three moments in the history of post-conflict identification science. Through a close attention to the material semiotic networks of forensic science in post-conflict settings, I examine the shifting ground between non-governmental human rights forensics and an emerging security- and disaster-focused identification grounded in global law enforcement. I argue that these transformations are aligned with a scientific shift towards mechanized, routinized, and corporate-owned DNA identification and a legal privileging of the right to truth circumscribed by narrow articulations of kinship and the body.

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29

Tobe, Shanan S., and Adrian M. T. Linacre. "A technique for the quantification of human and non-human mammalian mitochondrial DNA copy number in forensic and other mixtures." Forensic Science International: Genetics 2, no. 4 (September 2008): 249–56. http://dx.doi.org/10.1016/j.fsigen.2008.03.002.

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30

Tian, Huan, Peng Bai, Yu Tan, Zhilong Li, Duo Peng, Xiao Xiao, Huan Zhao, Yan Zhou, Weibo Liang, and Lin Zhang. "A new method to detect methylation profiles for forensic body fluid identification combining ARMS-PCR technique and random forest model." Forensic Science International: Genetics 49 (November 2020): 102371. http://dx.doi.org/10.1016/j.fsigen.2020.102371.

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31

Hamajima, Nobuyuki. "PCR-CTPP: a new genotyping technique in the era of genetic epidemiology." Expert Review of Molecular Diagnostics 1, no. 1 (May 2001): 119–23. http://dx.doi.org/10.1586/14737159.1.1.119.

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32

Moskovitch, Guillaume, Fabrice Dedouit, José Braga, Daniel Rougé, Hervé Rousseau, and Norbert Telmon. "Multislice Computed Tomography of the First Rib: A Useful Technique for Bone Age Assessment." Journal of Forensic Sciences 55, no. 4 (March 25, 2010): 865–70. http://dx.doi.org/10.1111/j.1556-4029.2010.01390.x.

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33

Linville, Jason G., Jack Hayes, and Jeffrey D. Wells. "Mitochondrial DNA and STR Analyses of Maggot Crop Contents: Effect of Specimen Preservation Technique." Journal of Forensic Sciences 49, no. 2 (2004): 1–4. http://dx.doi.org/10.1520/jfs2003266.

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34

Hedman, Johannes, Linda Jansson, Yasmine Akel, Nanny Wallmark, Rebecca Gutierrez Liljestrand, Christina Forsberg, and Ricky Ansell. "The double-swab technique versus single swabs for human DNA recovery from various surfaces." Forensic Science International: Genetics 46 (May 2020): 102253. http://dx.doi.org/10.1016/j.fsigen.2020.102253.

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35

Falys, Ceri G., Holger Schutkowski, and Darlene A. Weston. "The Distal Humerus—A Blind Test of Rogers' Sexing Technique Using a Documented Skeletal Collection." Journal of Forensic Sciences 50, no. 6 (2005): 1–5. http://dx.doi.org/10.1520/jfs2005171.

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36

van Gijlswijk, Rob P. M., Eduard G. Talman, Patrick J. A. Janssen, Sandor S. Snoeijers, Jeffrey Killian, Hans J. Tanke, and Robert J. Heetebrijl. "Universal Linkage System: versatile nucleic acid labeling technique." Expert Review of Molecular Diagnostics 1, no. 1 (May 2001): 81–91. http://dx.doi.org/10.1586/14737159.1.1.81.

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37

Gomes, Cláudia, Alejandro Alonso, Domingo Marquina, Marc Guardià, César López-Matayoshi, Sara Palomo-Díez, Bernardo Perea-Peréz, Juan F. Gibaja, and Eduardo Arroyo-Pardo. "“Inhibiting inhibitors”: Preliminary results of a new “DNA extraction-amplification” disinhibition technique in critical human samples." Forensic Science International: Genetics Supplement Series 6 (December 2017): e197-e199. http://dx.doi.org/10.1016/j.fsigss.2017.09.066.

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38

Berendes, Antje, Dieter Neimke, Rüdiger Schumacher, and Martin Barth. "A Versatile Technique for the Investigation of Gunshot Residue Patterns on Fabrics and Other Surfaces: m-XRF." Journal of Forensic Sciences 51, no. 5 (September 2006): 1085–90. http://dx.doi.org/10.1111/j.1556-4029.2006.00225.x.

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39

Byard, Roger W. "Thoracic Visceral Compression–A Useful Technique for Demonstrating Small Bleeding Points in the Dissected Neck at Autopsy." Journal of Forensic Sciences 65, no. 1 (August 30, 2019): 274–75. http://dx.doi.org/10.1111/1556-4029.14176.

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40

Machida, Mitsuyo, Takashi Taki, and Kazuhiko Kibayashi. "Screening for single nucleotide polymorphisms in highly degraded DNA by using the amplified fragment length polymorphism technique." Forensic Science International: Genetics 31 (November 2017): 5–11. http://dx.doi.org/10.1016/j.fsigen.2017.08.007.

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41

Gross, T., J. Thomson, and S. Kutranov. "A review of low template STR analysis in casework using the DNA SenCE post-PCR purification technique." Forensic Science International: Genetics Supplement Series 2, no. 1 (December 2009): 5–7. http://dx.doi.org/10.1016/j.fsigss.2009.08.111.

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42

Calce, Stephanie E., and Tracy L. Rogers. "Evaluation of Age Estimation Technique: Testing Traits of the Acetabulum To Estimate Age at Death in Adult Males*." Journal of Forensic Sciences 56, no. 2 (February 9, 2011): 302–11. http://dx.doi.org/10.1111/j.1556-4029.2011.01700.x.

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43

Mao, Shiwei, Feng Fu, Xiuzhen Dong, and Zhenyuan Wang. "Supplementary Pathway for Vitality of Wounds and Wound Age Estimation in Bruises Using the Electric Impedance Spectroscopy Technique." Journal of Forensic Sciences 56, no. 4 (March 21, 2011): 925–29. http://dx.doi.org/10.1111/j.1556-4029.2011.01756.x.

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44

Bernitz, Herman, Willie F. P. van Heerden, Tore Solheim, and Johanna H. Owen. "A Technique to Capture, Analyze, and Quantify Anterior Teeth Rotations for Application in Court Cases Involving Tooth Marks." Journal of Forensic Sciences 51, no. 3 (May 2006): 624–29. http://dx.doi.org/10.1111/j.1556-4029.2006.00114.x.

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45

Buddhakosai, Waradee, Manakorn Sukmak, Worata Klinsawat, Somphot Duangchantrasiri, Achara Simcharoen, Boripat Siriaroonrat, and Worawidh Wajjwalku. "Discrimination of tiger using a novel high resolution melting (HRM) and multiplex SNP-specific HRM (MSS-HRM) technique." Forensic Science International: Genetics 13 (November 2014): 30–33. http://dx.doi.org/10.1016/j.fsigen.2014.07.001.

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46

Hakim, Hashom Mohd, Hussein Omar Khan, Japareng Lalung, Bryan Raveen Nelson, Geoffrey Keith Chambers, and Hisham Atan Edinur. "Autosomal STR Profiling and Databanking in Malaysia: Current Status and Future Prospects." Genes 11, no. 10 (September 23, 2020): 1112. http://dx.doi.org/10.3390/genes11101112.

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Science and technology are extensively used in criminal investigation. From the mid- to late-1980s, one of the scientific discoveries that has had a particularly remarkable impact on this field has been the use of highly variable DNA sequence regions (minisatellites) in the human genome for individual identification. The technique was initially referred to as DNA fingerprinting, but is now more widely referred to as DNA profiling. Since then, many new developments have occurred within this area of science. These include the introduction of new genetic markers (microsatellites also known as short tandem repeats/STRs), the use of the polymerase chain reaction for target amplification, the development of DNA databases (databanking), and the advancement and/or improvement of genotyping protocols and technologies. In 2019, we described the progress of DNA profiling and DNA databanking in Malaysia for the first time. This report included information on DNA analysis regulations and legislation, STR genotyping protocols, database management, and accreditation status. Here, we provide an update on the performance of our DNA databank (numbers of DNA profiles and hits) plus the technical issues associated with correctly assigning the weight of evidence for DNA profiles in an ethnically diverse population, and the potential application of rapid DNA testing in the country. A total of 116,534 DNA profiles were obtained and stored in the Forensic DNA Databank of Malaysia (FDDM) by 2019, having increased from 70,570 in 2017. The number of hits increased by more than three-fold in just two years, where 17 and 69 hits between the DNA profiles stored in the FDDM and those from crime scenes, suspects, detainees, drug users, convicts, missing persons, or volunteers were recorded in 2017 and 2019, respectively. Forensic DNA analysis and databanking are thus progressing well in Malaysia and have already contributed to many criminal investigations. However, several other issues are discussed here, including the need for STR population data for uncharacterized population groups, and pilot trials for adopting rapid DNA profiling technology. These aspects should be considered by policy makers and law enforcement agencies in order to increase the reliability and efficiency of DNA profiling in criminal cases and in kinship analysis in Malaysia.

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47

Thevissen, Patrick W., Pisha Pittayapat, Steffen Fieuws, and Guy Willems. "Estimating Age of Majority on Third Molars Developmental Stages in Young Adults from Thailand Using a Modified Scoring Technique." Journal of Forensic Sciences 54, no. 2 (March 2009): 428–32. http://dx.doi.org/10.1111/j.1556-4029.2008.00961.x.

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48

Khatoon, Fahmida. "RECENT TECHNIQUES BASED ON THE UTILIZATION OF DNA AND AUTOSOMAL SINGLE NUCLEOTIDE POLYMORPHISMS FOR IDENTIFYING HUMANS." Gomal Journal of Medical Sciences 17, no. 2 (June 30, 2019): 58–62. http://dx.doi.org/10.46903/gjms/17.02.2022.

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The biological samples used in forensics can contain DNA which is highly fragmented as a consequence of exposure to any of the numerous degrading factors. Analysis of the sequence or size of the products of Polymerase chain reaction is at present responsible for the analysis of remains of humans in forensics. Despite the effectiveness of protocols based on PCR, there are certain limitations that are presented by the low numbers of copies of the template and the variations that are imposed by the decaying process to the template. The primary aim of this research is to explore the significance of autosomal SNPs in forensic science through the identification of humans at a crime scene. This study provides an exploration of the applicability of autosomal SNPs for the identification of humans at crime scene. This would fill the gap present in the current literature regarding the significance of autosomal SNPs in the identification of humans during crime scene investigation. It will also enable the identification of the criminals involved in several types of the crimes ranging from general theft to rape and sexual assault, murder, and robberies. It will also allow the identification of dead bodies in cases where it is difficult to identify the dead person due to unrecognizable condition of the body. This study will facilitate the improvement of the investigation of crime scene investigators. It will provide a significant way for the incorporation of recent techniques of the molecular genetics into forensics. Reduction in the workload of the crime scene investigators would also occur through the implementation of outcomes of this study into the field of forensic science. There are several studies which have demonstrated the applicability of SNPs in forensic investigations for identifying the humans at crime scene. Several effective and efficient technological systems have been developed by the researchers which are capable of performing analysis of biological samples containing degraded DNA because SNPs can be obtained from these samples. Physical characteristics of the individuals can be predicted through the analysis of SNPs. This can provide significant information about the color of eye, hair and skin of the individuals involved in crime.

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49

Živković, Vladimir, Danica Cvetković, and Slobodan Nikolić. "Commentary on: Langlois NEI , Byard RW . Arterial perfusion—a useful technique for evaluating incised wounds. J Forensic Sci https://doi.org/10.1111/1556-4029.13682. Epub 2017 Oct 30." Journal of Forensic Sciences 63, no. 2 (March 2018): 650. http://dx.doi.org/10.1111/1556-4029.13708.

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50

Monteiro, Samantha Lopes, Ívna Soares de Oliveira, and Tarcísio André Amorim de Carvalho. "Análise transdisciplinar do Banco Nacional de Perfis Genéticos: técnicas moleculares e aspectos jurídicos." Revista Brasileira de Criminalística 8, no. 1 (June 28, 2019): 48–53. http://dx.doi.org/10.15260/rbc.v8i1.347.

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O uso de marcadores moleculares para a identificação humana é uma estratégia aplicada nas atividades forenses no Brasil. A criação de bancos de perfis genéticos é uma tendência mundial. É esperado que o uso de tais dados não somente facilite a investigação de casos criminais, mas também leve à redução da criminalidade. O presente artigo objetiva-se realizar uma análise transdisciplinar sobre o Banco Nacional de Perfis Genéticos (BNPG), abordando a funcionalidade dele, apresentando também as técnicas moleculares aplicadas, além de suscitar discussões jurídicas geradas com a implantação do banco de dados nacional. Trata-se de uma revisão bibliográfica exploratória que foi elaborada a partir de uma pesquisa realizada em bases de dados bibliográficos como SciELO, PubMed e JusBrasil. A conscientização da funcionalidade potencial dessa ferramenta poderá despertar o interesse de mais especialistas de ambas as áreas, biológica e jurídica, para que possam aperfeiçoá-la e, futuramente, desenvolver outras aplicações.Palavras-Chave: Identificação Humana; DNA Forense; Banco de Dados; Ciências Forenses; Lei 12.654/12. AbstractThe use of molecular markers for human identification is a strategy applied in forensic investigation in Brazil. The creation of DNA databases is a worldwide trend. It is expected that the use of such data will not only assist investigation of criminal cases, but also lead to reduced crime. The present article aims to carry out a transdisciplinary analysis about the Brazilian National Genetic Profile Database, addressing its functionality, presenting also applied molecular techniques, as well as raising legal discussions generated with the implementation of the national DNA database. It is an exploratory bibliographic review that was elaborated from a research carried out in bibliographic databases like SciELO, PubMed and JusBrasil. Awareness of the potential functionality of this tool may raise the interest of more specialists in both biological and legal areas so that they can improve it and promote it in the future.Keywords: Human Identification; Forensic DNA; Database; Forensic Science; Law 12.654/12.

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