Academic literature on the topic 'Forced oscillation technique'

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Journal articles on the topic "Forced oscillation technique"

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Nielsen, Kim G. "Forced oscillation technique." Paediatric Respiratory Reviews 7 (January 2006): S8—S10. http://dx.doi.org/10.1016/j.prrv.2006.04.021.

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Thurgood, Jordan, Stephen Dubsky, Kentaro Uesugi, Michael Curtis, Chaminda R. Samarage, Bruce Thompson, Graeme Zosky, and Andreas Fouras. "Imaging lung tissue oscillations using high-speed X-ray velocimetry." Journal of Synchrotron Radiation 23, no. 1 (January 1, 2016): 324–30. http://dx.doi.org/10.1107/s1600577515021700.

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This work utilized synchrotron imaging to achieve a regional assessment of the lung's response to imparted oscillations. The forced oscillation technique is increasingly being used in clinical and research settings for the measurement of lung function. During the forced oscillation technique, pressure oscillations are imparted to the lungsviathe subjects' airway opening and the response is measured. This provides information about the mechanical properties of the airways and lung tissue. The quality of measurements is dependent upon the input signal penetrating uniformly throughout the lung. However, the penetration of these signals is not well understood. The development and use of a novel image-processing technique in conjunction with synchrotron-based imaging was able to regionally assess the lungs' response to input pressure oscillation signals in anaesthetized mice. The imaging-based technique was able to quantify both the power and distribution of lung tissue oscillations during forced oscillations of the lungs. It was observed that under forced oscillations the apices had limited lung tissue expansion relative to the base. This technique could be used to optimize input signals used for the forced oscillation technique or potentially as a diagnostic tool itself.
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Mochizuki, Hiroyuki, Kota Hirai, and Hideyuki Tabata. "Forced Oscillation Technique and Childhood Asthma." Allergology International 61, no. 3 (2012): 373–83. http://dx.doi.org/10.2332/allergolint.12-rai-0440.

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Demedts, M., J. A. Van Noord, and K. P. Van De Woestijne. "Clinical Applications of Forced Oscillation Technique." Chest 99, no. 4 (April 1991): 795–97. http://dx.doi.org/10.1378/chest.99.4.795.

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Ngo, Chuong, Falk Dippel, Sylvia Lehmann, Klaus Tenbrock, Thomas Vollmer, Berno Misgeld, and Steffen Leonhardt. "The volume-dependent Forced Oscillation Technique." IFAC-PapersOnLine 51, no. 27 (2018): 373–77. http://dx.doi.org/10.1016/j.ifacol.2018.11.611.

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Chen, Zengshun, Yemeng Xu, Hailin Huang, and Kam Tim Tse. "Wind Tunnel Measurement Systems for Unsteady Aerodynamic Forces on Bluff Bodies: Review and New Perspective." Sensors 20, no. 16 (August 17, 2020): 4633. http://dx.doi.org/10.3390/s20164633.

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Wind tunnel tests have become one of the most effective ways to evaluate aerodynamics and aeroelasticity in bluff bodies. This paper has firstly overviewed the development of conventional wind tunnel test techniques, including high frequency base balance technique, static synchronous multi-pressure sensing system test technique and aeroelastic test, and summarized their advantages and shortcomings. Subsequently, two advanced test approaches, a forced vibration test technique and hybrid aeroelastic- force balance wind tunnel test technique have been comprehensively reviewed. Then the characteristics and calculation procedure of the conventional and advanced wind tunnel test techniques were discussed and summarized. The results indicated that the conventional wind tunnel test techniques ignored the effect of structural oscillation on the measured aerodynamics as the test model is rigid. A forced vibration test can include that effect. Unfortunately, a test model in a forced vibration test cannot respond like a structure in the real world; it only includes the effect of structural oscillation on the surrounding flow and cannot consider the feedback from the surrounding flow to the oscillation test model. A hybrid aeroelastic-pressure/force balance test technique that can observe unsteady aerodynamics of a test model during its aeroelastic oscillation completely takes the effect of structural oscillation into consideration and is, therefore, effective in evaluation of aerodynamics and aeroelasticity in bluff bodies. This paper has not only advanced our understanding for aerodynamics and aeroelasticity in bluff bodies, but also provided a new perspective for advanced wind tunnel test techniques that can be used for fundamental studies and engineering applications.
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Shirai, Toshihiro, and Hajime Kurosawa. "Clinical Application of the Forced Oscillation Technique." Internal Medicine 55, no. 6 (2016): 559–66. http://dx.doi.org/10.2169/internalmedicine.55.5876.

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Franken, H., M. Cauberghs, A. Ringelhann, J. Clement, and K. P. Van de Woestijne. "Forced oscillation technique: comparison of two devices." Journal of Applied Physiology 59, no. 5 (November 1, 1985): 1654–59. http://dx.doi.org/10.1152/jappl.1985.59.5.1654.

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The respiratory impedances in healthy subjects and patients with advanced obstructive lung disease were measured between 2 and 32 Hz, using two forced oscillation techniques: the setup used previously by Grimby et al. (J. Clin. Invest. 47: 1455–1465, 1968) and a modified device in which the pneumotachograph is replaced by a 2-m-long tube and the ratio of pressures at both ends of the tube is determined. The advantages of the latter device are that 1) its impedance and frequency characteristics can be predicted by classical physics, 2) the only requirement for correct measurements are a match of the pressure transducers, and 3) high-pass filters are not needed to suppress the influence of breathing. On the other hand, the device is more sensitive to the turbulences induced by the subject's own breathing. This drawback can be avoided by interposing a piece of tubing between the mouth and proximal pressure recording site.
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Gauld, Leanne M., Lucy A. Keeling, Claire E. Shackleton, and Peter D. Sly. "Forced Oscillation Technique in Spinal Muscular Atrophy." Chest 146, no. 3 (September 2014): 795–803. http://dx.doi.org/10.1378/chest.14-0166.

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Shirai, Toshihiro, Keita Hirai, Yasuhiro Gon, Shuichiro Maruoka, Kenji Mizumura, Mari Hikichi, Kunihiko Itoh, and Shu Hashimoto. "Forced oscillation technique may identify severe asthma." Journal of Allergy and Clinical Immunology: In Practice 7, no. 8 (November 2019): 2857–60. http://dx.doi.org/10.1016/j.jaip.2019.05.036.

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Dissertations / Theses on the topic "Forced oscillation technique"

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Wouters, Emiel Frans Maria. "Bronchial response in COPD measured by forced oscillation technique." Maastricht : Maastricht : Rijksuniversiteit Limburg ; University Library, Maastricht University [Host], 1987. http://arno.unimaas.nl/show.cgi?fid=5376.

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Macleod, Dominic Paul. "Use of a within-breath forced oscillation technique : development and clinical applications." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298301.

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Everson, Daniel Peter. "Development of a forced oscillation test technique for determination of MAV stability characteristics." College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/3236.

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Thesis (M.S.) -- University of Maryland, College Park, 2005.
Thesis research directed by: Dept. of Aerospace Engineering. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Gangell, Catherine Louise. "Evaluation of the forced oscillation technique for clinical assessment of young children with cystic fibrosis." University of Western Australia. School of Paediatrics and Child Health, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0213.

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Background: Measurements of lung function are routinely used in patients with cystic fibrosis (CF) to provide information that may be clinically relevant. Spirometry is the conventional lung function measurement used, however young children find spirometry difficult to perform and often cannot achieve the strict acceptability criteria for the test. The forced oscillation technique (FOT) is a lung function measurement that only requires tidal breathing and is easy for young children to perform. However, there is limited information about the utility of this technique in the clinical assessment of young children with CF who are unable to perform spirometry. Aims: The aim of this project was to evaluate the FOT for clinical assessment in 2 to 7 year old children with CF. Specifically this involved: 1. Technical assessment of the FOT in children with CF; 2. Comparisons of lung function using the FOT in children with CF and healthy children; 3. Evaluation of associations with factors known to be associated with lung disease including: i) inflammation ii) infection and iii) structural damage. Methods Lung function was measured in a cohort of 59 children between the ages of 2 and 7 years with CF at the time of quarterly clinic visits. Resistance and reactance at 6, 8 and 10Hz (Rrs6, Rrs8, Rrs10, Xrs6, Xrs8, Xrs10, respectively) were reported and expressed as Z scores. Children were classified as asymptomatic or symptomatic based on a respiratory questionnaire and physical examination at the time of testing. Bronchoalveolar lavage and high resolution computed tomography (HRCT) were performed annually under general anaesthesia annually. BAL fluid was assessed for the presence of micro-organisms and quantification of a range of inflammatory markers and HRCT used to determine the extent of structural abnormalities. Results: The between test repeatability (n=25) for lung function was within limits previously described in healthy children. No systematic bias was observed and repeatability was not affected by the presence of respiratory symptoms. Children with CF (n=57) had significantly increased Rrs6-10 (p<0.0001) and decreased Xrs6-10 (p<0.004) compared to healthy children. Rrs6 and Xrs6-10 were significantly worse in the presence of respiratory symptoms, and Rrs6-10 progressively worsened from an asymptomatic to a symptomatic clinic visit. Children with CF (n=48) had no greater bronchodilator response (BDR) compared to healthy children. BDR was not influenced by the presence of an infection or respiratory symptoms. No relationships between inflammatory markers and lung function (n=39) were identified when the presence of an infection was adjusted for. Children with a current infection (n=20) had increased Rrs6-10 (p<0.01) and decreased Xrs6-10 (p<0.04) compared to children who were uninfected (n=23). These relationships were most marked for children infected with Pseudomonas aeruginosa, with children having a reduced lung function between 0.95 and 1.47 of a Z score. No relationships with the presence or absence of mild structural abnormalities (bronchiectasis, bronchial wall thickening and air trapping) and lung function at the time of HRCT were identified (n=34). Conclusion: The FOT is a repeatable measurement of lung function in children with CF and reliable results can be obtained in children as young as 2 years old. Young children with CF exhibit altered respiratory function which was affected by the presence of factors known to be associated with lung disease. The FOT has the potential to provide useful information about changes in clinical status in young children with CF and may be used to direct management of patient lung disease.
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Kostic, Peter. "New methods for optimization of mechanical ventilation." Doctoral thesis, Uppsala universitet, Anestesiologi och intensivvård, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-249172.

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Mechanical ventilation saves lives, but it is an intervention fraught with the potential for serious complications. Prevention of these complications has become the focus of research and critical care in the last twenty years. This thesis presents the first use, or the application under new conditions, of three technologies that could contribute to optimization of mechanical ventilation. Optoelectronic plethysmography was used in Papers I and II for continuous assessment of changes in chest wall volume, configuration, and motion in the perioperative period. A forced oscillation technique (FOT) was used in Paper III to evaluate a novel positive end-expiratory pressure (PEEP) optimization strategy. Finally, in Paper IV, FOT in conjunction with an optical sensor based on a self-mixing laser interferometer (LIR) was used to study the oscillatory mechanics of the respiratory system and to measure the chest wall displacement. In Paper I, propofol anesthesia decreased end-expiratory chest wall volume (VeeCW) during induction, with a more pronounced effect on the abdominal compartment than on the rib cage. The main novel findings were an increased relative contribution of the rib cage to ventilation after induction of anesthesia, and the fact that the rib cage initiates post-apneic ventilation. In Paper II, a combination of recruitment maneuvers, PEEP, and reduced fraction of inspired oxygen, was found to preserve lung volume during and after anesthesia. Furthermore, the decrease in VeeCW during emergence from anesthesia, associated with activation of the expiratory muscles, suggested that active expiration may contribute to decreased functional residual capacity, during emergence from anesthesia. In the lavage model of lung injury studied in Paper III, a PEEP optimization strategy based on maximizing oscillatory reactance measured by FOT resulted in improved lung mechanics, increased oxygenation, and reduced histopathologic evidence of ventilator-induced lung injury. Paper IV showed that it is possible to apply both FOT and LIR simultaneously in various conditions ranging from awake quiet breathing to general anesthesia with controlled mechanical ventilation. In the case of LIR, an impedance map representing different regions of the chest wall showed reproducible changes during the different stages that suggested a high sensitivity of the LIR-based measurements.
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Heijkenskjöld, Rentzhog Charlotte. "Towards Improved Diagnostics and Monitoring in Childhood Asthma : Methodological and Clinical Aspects of Exhaled NO and Forced Oscillation Technique." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-304264.

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Background: Asthma is a heterogeneous disease. Diagnosis relies on symptom evaluation and lung function tests using spirometry. Symptoms can be vague. Spirometry is effort-dependent and does not reliably evaluate small airways. Allergic asthma in preschool children is not easily separated from episodic wheeze. Exhaled NO (FeNO) is a marker of allergic Th2-cytokine-driven airway inflammation. However, FeNO is not feasible in preschoolers with current devices and algorithms. Alveolar NO is an estimate of small airway involvement. Forced oscillometry (FOT) is an effort-independent lung function test assessing both large and small airways. Aims: To study clinical and methodological aspects of FeNO, alveolar NO and lung function indices by FOT. Methods: Asthmatic children and young adults and healthy controls, were included in the studies. FeNO at 50 mL/s was performed in all studies (in study III with an adapted single-breath method with age-adjusted exhalation times). FeNO at multiple exhalation flow rates were performed in studies I, II and IV to calculate alveolar NO, as was spirometry. FOT indices were assessed in study IV. Results: The exhalation time needed to reach steady-state NO was < 4 s in subjects aged 3-4 years, and was related to subject height. FeNO was higher in ICS-naïve asthmatic children than in controls. ICS-naïve asthmatic preschool children had FeNO < 20 ppb. The oral contribution to FeNO was similar in asthmatic and healthy youths. Multiple flow rates and modelling of alveolar NO were feasible in children aged 10-18 years. Alveolar NO correlated to asthma characteristics, though not when axial diffusion correction was applied. FOT resistance measures were associated with asthma diagnosis, and small airway FOT measures were associated with asthma control, in adolescents. Conclusion: An adapted FeNO method is feasible from 4 years, and exhalation time is related to child height. Our findings emphasise the need to refine clinical cut-offs for FeNO in younger children. FOT variables discriminate between asthmatics and controls, much like spirometry. The information provided by FOT is additive to that from spirometry. Further studies of exhaled NO dynamics and FOT indices of small airways are warranted to evaluate new treatment options and possibly improve asthma control.
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Nirav, Daphtary. "Lung Impedance Measurements Using Tracked Breathing." ScholarWorks @ UVM, 2010. http://scholarworks.uvm.edu/graddis/162.

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The forced Oscillation Technique (FOT) can be used to measure lung impedance continuously during breathing. However, spectral overlap between the breathing waveform and the applied flow oscillation can be problematic if the frequency content of spontaneous breathing is unknown. This problem motivated us to develop a modification to the FOT system called the Tracked Breathing Trainer. The modification uses biofeedback to constrain subjects to breathe at a single predetermined frequency. This thesis investigates the engineering and physiological aspects of the modification we made. We studied 8 adult non-asthmatic and 8 adult asthmatic subjects. Three 16 s perturbatory flow oscillation signals ranging from 1-40 Hz were used on the subjects. Each subject received three trials per perturbation for both spontaneous and tracked breathing. We then fitted a resistance-elastance-inertance model of the lung to each data set. For non-asthmatic subjects, the average resistance (R) and elastance (E) values for the first spontaneous breathing trial were 2.5±0.15 cmH2O.s.ml-1 and 18.1±3.55 cmH2O.ml-1, and for the third spontaneous breathing trial were 2.4±0.12 cmH2O.s.ml-1 and 21.8±4 cmH2O.ml-1. R and E for the first tracked breathing trial were 2.3±0.21 cmH2O.s.ml-1 and 33.6±7.4 cmH2O.ml-1, and for the third tracked breathing trial were 2.4±0.14 cmH2O.s.ml-1 and 25.75±4.3 cmH2O.ml-1, respectively. For asthmatic subjects, the average R and E values for the first spontaneous breathing trial were 3.32±0.68 cmH2O.s.ml-1 and 39.13±9.8 cmH2O.ml-1, and for the third spontaneous breathing trial were 3.12±0.15 cmH2O.s.ml-1 and 39.91±6.2 cmH2O.ml-1. R and E for the first tracked breathing trial were 2.86±0.15 cmH2O.s.ml-1 and 32.47±4.1 cmH2O.ml-1, and for the third tracked breathing trial were 2.86±0.21 cmH2O.s.ml-1 and 33.89±10 cmH2O.ml-1, respectively. These results show that R was consistently lower during tracked breathing than spontaneous breathing in both non-asthmatic and asthmatic subjects. However, an increase in E was observed during tracked breathing. We suspect this effect may have resulted from dynamic hyperinflation. These results also show that R and E are reproducible with both spontaneous and tracked breathing, and that R and E were not noticeably different between both breathing maneuvers. We conclude that using biofeedback to control the breathing pattern during application of the FOT in normal subjects does not significantly affect impedance measurements, and thus may be useful for avoiding spectral overlap between FOT perturbations and the breathing pattern.
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Tramont, Caio Vinícius Villalón. "Análise das alterações decorrentes do envelhecimento na mecânica respiratória pela técnica de oscilações forçadas." Universidade do Estado do Rio de Janeiro, 2009. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=2269.

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O crescimento do percentual de idosos na população ocorre mundialmente tornando necessário conhecer o impacto do processo de envelhecimento, neste contexto, do sistema respiratório. O desconhecimento do impacto do envelhecimento associado a diferentes graus de exposição a poluentes e a presença de comorbidade(s) dificulta a diagnose das pneumopatias acarretando aos idosos piora da qualidade de vida. São vantagens da Técnica de Oscilações Forçadas (FOT): alto potencial de aplicação em idosos, fácil realização, análise detalhada da mecânica respiratória, desempenho de papel complementar, bem como de alternativa na impossibilidade de realização dos exames tradicionais. Foi realizado um estudo experimental comparativo que objetivou investigar o impacto do envelhecimento no sistema respiratório pela FOT e pela espirometria entre grupos de diferentes faixas etárias, sendo a idade a variável independente e as variáveis dependentes, os parâmetros oscilométricos resistência em regime contínuo (R0) e das vias aéreas centrais (Rm), inclinação da resistência (S), frequência de ressonância (fr), reatância média (Xm), complacência dinâmica (Cdin,sr) e os parâmetros espirométricos (VEF1, CVF, VEF1/CVF e FEF/CVF). Foram realizados entrevista, exame clínico, radiografia torácica, avaliação da mecânica respiratória pela FOT e da função pulmonar pela espirometria. 255 indivíduos com idades entre 20 e 86 anos foram entrevistados. Destes, 175 foram excluídos, restando os 80 voluntários analisados, que foram divididos em 6 grupos de acordo com a faixa etária (A: 20 a 29 anos; B: 30 a 39 anos; C: 40 a 49 anos; D: 50 a 59 anos; E: 60 a 69 anos; F: 70 anos ou mais). Foram utilizados os testes de Shapiro-Wilkins, na avaliação da normalidade dos dados biométricos em cada grupo, Oneway ANOVA, na comparação entre os grupos, e Tukey HSD na comparação entre as classes subjacentes. A análise da associação entre duas variáveis foi realizada inicialmente pela regressão univariada entre os parâmetros oscilométricos, a idade e a altura. A regressão múltipla entre os parâmetros oscilométricos, idade e altura foi realizada em conjunto. Foi realizada a análise de confundimento ou modificação de efeito sobre o parâmetro altura na relação entre a idade e os parâmetros oscilométricos. A correção pelo fator altura foi realizada quando sua análise apresentava fator de confundimento. Quanto aos parâmetros resistivos, não foram observadas alterações em R0 e Rm com o envelhecimento enquanto que o declínio observado em S é discreto e não-significativo. Em relação aos parâmetros reativos, verificouse que Cdin,sr e Xm diminuem enquanto que fr aumenta com o processo de envelhecimento. Todas estas alterações são significativas. Todavia, a diminuição da Cdin,sr não apresenta relação com a idade e sim com a altura, que constituiu modificação do efeito. Nos demais parâmetros oscilométricos, a altura constituiu fator de confundimento. Quanto à espirometria, observou-se declínio significativo do VEF1, do VEF1/CVF e da CVF. O índice FEF/CVF apresentou declínio nãosignificativo. Concluindo, a resistência do sistema respiratório e a complacência dinâmica não se modificam enquanto a homogeneidade do sistema respiratório diminui com o processo de envelhecimento.
The increase in the elderly percentage in the population occurs worldwide. To know the impact of the aging process, in this context, on the respiratory system, is crucial. The unawareness of the impact of aging, with different exposure degrees to pollution and the presence of commorbities introduces difficulty in the pneumopathies diagnosis make worsen the elderlys quality of life. The Forced Oscillation Technique (FOT) has as advantages a high application potential in elderly people, detailed analysis of the respiratory mechanics, plays complementary role and alternative in the impossibility to perform the traditional exams, as well. A comparative experimental study was done with the purpose of analyze the impact of aging in the respiratory system by FOT and spirometry between groups of different ages. Age is the independent variable and the dependent variables are the oscillometric parameters continuum regime resistance (R0), central airways resistance (Rm), slope of resistance (S), resonant frequency (fr), average reactance (Xm), dynamic compliance (Cdin,sr) and the spirometry parameters (FEV1, FVC, FEV1/CVF and FEF/FVC). Interviews, clinical examination, thoracic roentgenograms, mensuration of the respiratory mechanics by FOT and of the pulmonary function by spirometry were performed. 255 individuals aged from 20 to 86 years were interviewed. From these, 175 were excluded and the 80 remaining volunteers were analyzed and divided into six groups according to age (A: 20-29 years old; B: 30-39 years old; C: 40-49 years old; D: 50-59 years old; E: 60-69 years old; F: 70 or more years old). The Shapiro-Wilkins test was used in the analysis of the normality of the biometric data in each group. Oneway ANOVA was used in the comparison between groups and the Tukey HSD test was used in the comparison between the underlying classes. The analysis of the association between two variables was done initially between the oscilometric parameters, age and height. Multiple regressions between oscilometric parameters, age and height was performed in conjunction. Confounding analysis or effect modification over height and oscilometric parameters was done. The correction by the height factor was done when its analysis presented confounding factor. There were not changes in the resistive parameters R0 and Rm with age while the decrease seen in S is slight and not significant. In the reactive parameters, it was found that Cdin,sr and Xm decrease while fr increases with the aging process. All of these changes are significant. However, the decrease in Cdin,sr is not related to the aging process but with height, which was a confounding factor. It was found that the spirometric parameters FEV1, FVC and CVF presented a significant decrease and the index FEF/CVF presented a not significant decrease. Concluding, the resistance and the dynamic compliance of the respiratory system do not change while the homogeneity of the respiratory system decreases with the aging process.
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Peleteiro, Paula Morisco de Sá. "O uso da Técnica de Oscilações Forçadas na análise da mecânica ventilatória de indivíduos portadores de silicose classificados em diferentes graus de obstrução." Universidade do Estado do Rio de Janeiro, 2011. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=6294.

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O termo silicose refere-se ao processo de fibrose pulmonar causado pela inalação de poeira contendo sílica. É uma doença ocupacional, incurável, que se inicia nas vias aéreas distais e pode progredir independente do término da exposição. Os testes de função pulmonar, apesar de não serem utilizados como ferramenta diagnóstica para silicose, são amplamente empregados para acompanhar longitudinalmente esses indivíduos. Estudos recentes sugerem que a Técnicas de Oscilações Forçadas (FOT) pode ser aplicada para detecção de alterações pulmonares precoces em indivíduos com silicose. Contudo, existem poucos estudos descrevendo as alterações de mecância respiratória associada com a silicose através da FOT. Neste contexto, os objetivos deste estudo são: (1) analisar as alterações de mecânica respiratória de indivíduos portadores de silicose com diferentes graus de obstrução e (2) avaliar a capacidade da FOT em detectar alterações na função pulmonar decorrentes da silicose. Trata-se de um estudo transversal controlado com avaliação de casos prevalentes, tendo como unidade de avaliação o indivíduo. Os exames realizados incluíram medidas de espirometria e FOT. Foi selecionado um total de 67 indivíduos, 46 portadores de silicose e 21 sadios, caracterizando o grupo controle. Os indivíduos com diagnóstico de silicose foram divididos em três grupos classificados de acordo com o nível de obstrução sugerido pela espirometria. Essa classificação resultou em três categorias: Indivíduos normais ao exame espirométrico (NE), n= 12; com distúrbio ventilatório obstrutivo leve (DVOL), n=22; com distúrbio ventilatório obstrutivo moderado ou acentuado (DVOMA), n= 12. Todos os indivíduos realizaram exames da FOT para análise das propriedades resistivas e reativas do sistema respiratório. Posteriormente aos exames da FOT os indivíduos foram submetidos à espirometria. Considerando os grupos divididos a partir da espirometria, os parâmetros resistivos e reativos e a impedância do sistema respiratório em 4Hz (Z4Hz) se modificaram significativamente com a progressão da distúrbio obstrutivo. Na análise do poder diagnóstico da FOT os parâmetros R0, Rm, Rsr4 e |Z4Hz| mostraram-se precisos para identificar as modificações de mecânica respiratória em pacientes com silicose apresentando distúrbio ventilatório obstrutivo leve. Para distúrbio ventilatório obstrutivo moderado e acentuado todos os parâmetros analisados apresentaram habilidade para identificar essas alterações. Na análise entre o grupo controle e normal ao exame, nenhum parâmetro da FOT apresentou valor de acurácia adequado para uso clínico. Esses resultados são coerentes com as alterações fisiopatológicas relacionadas à silicose, confirmando o potencial da FOT na avaliação das modificações de mecânica respiratória em doentes com silicose.
The term silicosis is the name given to the pulmonary fibrosis caused by inhalation of dust containing crystalline silica. Is a typical occupational disease, chronic, incurable, starting in the peripheral airways and that can progress independently of the end of exposure. The pulmonary function tests, although not used as a diagnostic tool for silicosis, are widely employed to follow these individuals. Recent works suggests that the Forced Oscilation Technique (FOT) may be applied in the detection of early respiratory changes in silicosis. However, few studies have been analyzing the changes on respiratory mechanics associated with silicosis through the FOT. In this context, the aims of this study were (1) to analyze changes respiratory mechanics in subjects with silicosis with different degrees of obstruction by FOT, and (2) to evaluate the potential of the FOT to detect alterations in the lung function resulting from silicosis. This is a sectional study evaluation of prevalent cases, with the evaluation unit the individual. The examinations included measurement of FOT and spirometry. Sixty-seven volunteers were analyzed: 21 healthy subjects and 46 with silicosis. Spirometry was used to classify airway obstruction in the silicosis groups. This classification resulted in three categories: normal spirometric exam (n = 12); mild obstruction (n = 22); moderate or severe obstruction (n = 12.). All subjects performed FOT exam for the analysis of resistive and reactive properties of the respiratory system. The order of the examinations was FOT, followed by spirometry. Considering the groups classified according to the spirometry, the resistive and reactive the parameters and the impedance of the respiratory system at 4Hz (|Z4Hz|), have changed significantly with the progression of obstructive. The analysis of the diagnostic power of FOT parameters R0, Rm, and Rsr4 |Z4Hz| showed to be accurate to identify the changes of respiratory mechanics in silicosis patients with mild obstructive lung disease. To the moderate and severe obstructions, all the parameters analyzed showed adequate to identify these changes. In the analysis between the control and normal exam, no parameters of the FOT showed adequate measure to use to correctly identify these subjects. The FOT parameters adequately described the pathophysiological changes associated with silicosis and presented adequate accuracy for clinical use, indicating that this technique can be helpful in the evaluation respiratory mechanics in this disease.
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Souza, Georgia Alencar Franco de. "Análise das alterações de mecânica respiratória e da resposta broncodilatadora em crianças asmáticas por meio da Técnica de oscilações Forçadas." Universidade do Estado do Rio de Janeiro, 2010. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=2104.

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O aprofundamento de nosso conhecimento acerca das alterações da mecânica respiratória e da resposta ao uso do broncodilatador em crianças com asma pode contribuir para o melhor entendimento desta doença. A técnica de oscilações forçadas (FOT) apresenta elevado potencial neste sentido, pois permite uma avaliação detalhada da mecânica respiratória de crianças asmáticas. Desta maneira, os objetivos deste estudo são: (1) aprofundar nosso conhecimento sobre as alterações de mecânica respiratória em crianças asmáticas; (2) investigar o potencial de utilização clínica da FOT e (3) analisar as alterações de mecânica respiratória decorrentes da resposta broncodilatadora em crianças asmáticas. No presente estudo foram analisadas 93 crianças, separadas em grupo controle (n=31) e grupo de crianças asmáticas divididas de acordo com o grau de obstrução ao fluxo aéreo determinado pela espirometria em: normal ao exame espirométrico (n=31) e com distúrbio ventilatório obstrutivo leve (n=31). Pela FOT foram analisados os parâmetros relacionados às propriedades resistivas do sistema respiratório R0 (resistência no intercepto), Rm (resistência média) e S (inclinação da reta de resistência). R0 e Rm aumentaram com a obstrução ao fluxo aéreo (p<0,002 e p<0,02, respectivamente) e S apresentou redução (p<0,0007) caracterizando, este último, aumento da não-homogeneidade do sistema respiratório. Observou- se uma redução nos parâmetros relacionados às propriedades reativas do sistema respiratório, Cdin,sr (complacência dinâmica, p<0,03) e Xm (reatância média, p<0,02) com o aumento da obstrução. Também foi analisado o módulo da impedância em 4 Hz (׀Zrs4Hz׀), parâmetro relacionado com a carga mecânica total no sistema respiratório, que mostrou- se aumentado com a obstrução(p<0,001). Na análise do desempenho diagnóstico, os parâmetros R0, Rm, Cdin,sr e ׀Zrs4Hz׀ apresentaram área sob a Curva (AUC), sensibilidade (Se) e especificidade (Sp) adequados ao uso clínico no grupo com distúrbio ventilatório obstrutivo leve. Estes valores foram mais elevados do que no grupo de crianças asmáticas normais ao exame espirometrico, o que está relacionado com as maiores alterações no grupo com obstrutrução leve. A resposta broncodilatadora foi estudada observando- se as diferenças dentro do mesmo grupo de crianças e mensurando as alterações em cada grupo antes e após o uso do broncodilatador. Os parâmetros relacionados às propriedades resistivas, R0, Rm e S apresentaram melhora significativa com redução das resistências no grupo controle (p<0,00001, p<0,0003 e 0,00001), normal ao exame espirometrico (p<0,000002, p<0,00008 e 0,0006) e grupo com distúrbio ventilatório obstrutivo leve (p<0,0001, p<0,0007 e 0,000001). Estas alterações ocorreram no grupo controle e nos grupos de crianças asmáticas. Crs,din e Xm também apresentaram alterações significativas em todos os grupos estudados: no grupo controle (p<0,0001, p<0,00001), normal ao exame (p<0,00006, p<0,00001) e no grupo com distúrbio ventilatório obstrutivo leve (p<0,0001, p<0,00001), fato também observado na análise de ׀Zrs4Hz׀ no grupo controle (p<0,00001), normal ao exame (p<0,00001) e grupo com distúrbio ventilatório obstrutivo leve (p<0, 00001). Concluímos que a asma introduz alterações nos parâmetros resistivos e reativos do sistema respiratório com o aumento do grau de obstrução ao fluxo aéreo. Essas alterações foram identificadas nas crianças com obstrução leve. A FOT detectou as alterações ocorridas após a utilização da medicação broncodilatadora. Estes resultados indicam que a FOT pode ser um exame sensível para avaliar as alterações fisiopatológicas decorrentes da asma em crianças.
The increase of our knowledge about changes in respiratory mechanics and response to bronchodilator use in asthmatic children may contribute to a better understanding of this disease. The forced oscillation technique (FOT) has high potential in this sense, since it allows a detailed assessment of respiratory mechanics in asthmatic children. Thus, the objectives of this study are: (1) increase our understanding of the changes in respiratory mechanics of asthma in children, (2) investigate the clinical potential of FOT and (3) analyze the changes in respiratory mechanics resulting from bronchodilator response in asthmatic children. The present study examined 93 children, separated in the control group (n=31) and the asthmatic group divided according to the degree of airflow obstruction determined by spirometry in normal spirometry results (n=31) and with mild airway obstruction (n=31). Using the FOT we analyzed parameters related to the resistance of the respiratory system R0 (intercept resistance), Rm (resistance average) and S (slope of the resistance). R0 and Rm increased with airflow obstruction (p<0.002 and p<0.02, respectively) and S decreased (p<0.0007), indicating increased respiratory system non-homogeneity. There was a reduction in parameters related to the reactive properties of the respiratory system, Cst,sr (dynamic compliance, p<0.03) and Xm (reactance average, p<0,001) with increasing obstruction. The module of the respiratory system impedance at 4 Hz (| Zrs4Hz |) was also studied. This parameter is related to the total mechanical load on the respiratory system, and increased significantly with obstruction (p<0,001). Analyzing the diagnostic performance of FOT parameters, R0, Rm, Cst,sr and |Zrs4Hz| presented adequate values for clinical use in the identification of mild airway obstruction (AUC>0.7). These values were higher than that observed in the identification of the normal to the spirometric exam group, which may be related to the higher modifications in the group of children with mild airway obstruction. The bronchodilator response was studied by observing the differences within the same group of children, measuring the changes in each group before and after bronchodilator use. The parameters related to the resistance, R0, Rm and S showed significant improvement indicating reduced resistance in control group (p<0.00001,p<0.0003 e 0.00001), normal spirometry results (p<0.000002, p<0.00008 e 0.0006) and with mild airway obstruction (p<0.0001, p<0.0007 e 0.000001). These changes occurred in the control group and groups of children with asthma. Crs,din and Xm also showed significant changes in all groups studied in control group p<0.0001, p<0.00001), normal spirometry results (p<0.00006, p<0.00001) and with mild airway obstruction (p<0.0001, p<0.00001), a fact also observed in the analysis of | Zrs4Hz |, with showed a significant decrease in control group (p<0.00001), normal spirometry results(p<0.00001) and with mild airway obstruction (p<0.00001). We conclude that the increase of the degree of airflow obstruction in asthmatic children introduces increases in the resistance of the respiratory system, reductions in the dynamic compliance, reduction in homogeneity, as well as increase in the total respiratory system mechanical load. The FOT is able to detect respiratory changes in patients with mild airway obstruction. The use of bronchodilator medication introduces changes in asthmatic children, as well as in normal children. The results of the present study indicate that the FOT can be a sensitive test to evaluate the changes associated with asthma in children.
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Books on the topic "Forced oscillation technique"

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Deruelle, Nathalie, and Jean-Philippe Uzan. Deformations of celestial bodies. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198786399.003.0014.

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This chapter studies various gravitational effects arising from the non-sphericity of celestial bodies. It first considers the quadrupole expansion of the potential, as well as the causes of the non-sphericity of the bodies. Finally, it turns to the figure of the Earth. To calculate the proper potential of the Earth, it attempts to determine its deformation due to a perturbing potential. Doing this accurately requires knowledge of the internal structure of the Earth and use of the techniques of the mechanics of continuous media. In this approach, the internal stress–strain relationships of a body are described by various phenomenological parameters and it becomes possible to study the response of the body (deformation, oscillations, etc.) to the field of an external force.
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Thompson, William R., and Leila Zakhirova. Revising the Framework: Energy and Eurasian History. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190699680.003.0003.

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This chapter first theorizes as if each system leader has been similar in terms of the resource foundations it has brought to the arena and what it has been able to do with those foundations. Earlier leaders were much weaker than later leaders. What accounts for the difference? Our answer is that system leaders have had variable claims to leads in commerce, technology, and energy. When they combined all three, they became very powerful. The chapter then addresses one of the central issues of Big History: the swinging of the socioeconomic, military, and political lead from western Eurasia to eastern Eurasia and back to western Eurasia and North America in what is sometimes referred to as the “Great Divergence.” This oscillation was put in motion by the discovery of agricultural techniques that gave the West a lead to innovate all sorts of things. Gradually the East caught up, until at one point Rome and Han China were roughly equal. After Rome declined and the Han Empire fragmented, China came back in the Sui–Tang–Song dynasty period, while western Europe remained fragmented. However, the medieval Chinese lead did not persist. Ultimately, the West was able to forge ahead by combining new energy sources and technology. Now, China may be catching up once again.
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Book chapters on the topic "Forced oscillation technique"

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Navajas, Daniel, Raffaele L. Dellacà, and Ramon Farré. "Forced Oscillation Technique." In Mechanics of Breathing, 137–48. Milano: Springer Milan, 2014. http://dx.doi.org/10.1007/978-88-470-5647-3_10.

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Shirai, Toshihiro. "Clinical Application of the Forced Oscillation Technique (FOT)." In Advances in Asthma, 83–92. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2790-2_8.

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Hamakawa, Hiroshi, Hiroaki Sakai, Ayuko Takahashi, Jintian Zhang, Toshihiro Okamoto, Naoki Satoda, Akihiro Aoyama, et al. "Forced Oscillation Technique as a Non-Invasive Assessment for Lung Transplant Recipients." In Advances in Experimental Medicine and Biology, 293–98. Boston, MA: Springer US, 2009. http://dx.doi.org/10.1007/978-1-4419-1241-1_42.

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Mori, V., T. G. Kilmar, A. C. Fonseca, and H. T. Moriya. "Bandpass Speaker Box to Perform Forced Oscillation Technique Using the Wavetube Method." In VI Latin American Congress on Biomedical Engineering CLAIB 2014, Paraná, Argentina 29, 30 & 31 October 2014, 124–27. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13117-7_33.

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Hamakawa, Hiroshi, Hiroaki Sakai, Ayuko Takahashi, Toru Bando, and Hiroshi Date. "Multi-frequency Forced Oscillation Technique Using Impulse Oscillations: Can It Give Mechanical Information about the Lung Periphery?" In Advances in Experimental Medicine and Biology, 73–79. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4989-8_11.

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Parameswaran, Harikrishnan, and Béla Suki. "Assessing Structure–Function Relations in Mice Using the Forced Oscillation Technique and Quantitative Histology." In Methods in Molecular Biology, 77–91. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7163-3_8.

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Sancho, Alexandre G., Alvaro C. D. Faria, Jorge L. M. Amaral, Agnaldo J. Lopes, and Pedro L. Melo. "Evaluation of the Forced Oscillation Technique in the Differential Diagnosis of Obstructive and Restrictive Respiratory Diseases." In XXVI Brazilian Congress on Biomedical Engineering, 45–50. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2119-1_7.

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d’Alegria Tuza, Fábio Augusto, Paula Morisco de Sá, Agnaldo José Lopes, Hermano Albuquerque de Castro, and Pedro Lopes de Melo. "Evaluation of the Forced Oscillation Technique and the Extended RIC Model in the Analysis of Individuals with Work-Related Asthma." In XXVI Brazilian Congress on Biomedical Engineering, 37–43. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2119-1_6.

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Zheng, Yaqing, and Shuaihe Zhao. "Research Survey of Technique about Wire-Driven Parallel Suspension Systems Used in Forced Oscillation Experiments in Low-Speed Wind Tunnels for Obtaining Dynamic Derivatives." In Informatics in Control, Automation and Robotics, 131–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-25992-0_19.

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Marchal, F., and G. L. Hall. "Forced oscillation technique." In Paediatric Lung Function, 121–36. European Respiratory Society Journals Ltd, 2010. http://dx.doi.org/10.1183/1025448x.00012109.

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Conference papers on the topic "Forced oscillation technique"

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Shirai, Toshihiro, Keita Hirai, Yasuhiro Gon, Shuichiro Maruoka, Kenji Mizumura, Mari Hikichi, Kunihiko Itoh, and Shu Hashimoto. "Forced oscillation technique may identify severe asthma." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa2632.

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Simpson, Shannon J., Judy Park, Maureen Verheggen, Afaf Albloushi, Stephen M. Stick, and Graham Hall. "The Forced Oscillation Technique In Paediatric Respiratory Disease." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2351.

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Alemdaroglu, N., I. Iyigun, M. Altun, H. Uysal, F. Quagliotti, and G. Guglieri. "Determination of dynamic stability derivatives using forced oscillation technique." In 40th AIAA Aerospace Sciences Meeting & Exhibit. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2002. http://dx.doi.org/10.2514/6.2002-528.

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Almeida Borges, Joana Patrícia, and Fátima Fradinho. "Forced oscillation technique could make a difference in Sarcoidosis?" In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.3074.

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Ngo, Chuong, Falk Dippel, Sylvia Lehmann, Klaus Tenbrock, Thomas Vollmer, Berno Misgeld, and Steffen Leonhardt. "A novel technical extension of the Forced Oscillation Technique." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa1402.

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Seccombe, Leigh, Lachlan Buddle, Matthew Peters, and Claude Farah. "Exercise induced bronchoconstriction assessed using the forced oscillation technique." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3355.

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Mahadev, Sriram, Gregory King, Cheryl M. Salome, Chris Htun, and Robin Schoeffel. "Multifrequency Signals Identify Expiratory Flow Limitation Using Forced Oscillation Technique." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2185.

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Lauhkonen, Eero, Sindhu Sivagnanasithiyar, Georgios Kaltsakas, and Richard Iles. "Comparison of bronchodilator responsiveness between forced oscillation technique and spirometry." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa4573.

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Oostveen, E., and A. Zwart. "Transfer impedance of awake rats measured by the forced oscillation technique." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1988. http://dx.doi.org/10.1109/iembs.1988.94861.

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Yasuo, M., Y. Kitaguchi, Y. Tokoro, M. Kosaka, Y. Wada, T. Kinjyo, A. Ushiki, H. Yamamoto, and M. Hanaoka. "Difference Between Central and Peripheral Airway Obstructions by Forced Oscillation Technique." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2986.

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