Academic literature on the topic 'Foot diseases'

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Journal articles on the topic "Foot diseases"

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Yılmaz Deveci, Mehmet Zeki, and Hüseyin Erdal. "Determination of dynamic thiol-disulfide levels in dairy cattle with foot disease." Veterinarski arhiv 92, no. 6 (February 26, 2023): 657–66. http://dx.doi.org/10.24099/vet.arhiv.1785.

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Foot diseases are among the top three causes of economic loss in dairy cattle. Recent studies show that oxidative stress plays a critical role in the pathogenesis of foot diseases. There is no study determining the dynamic thiol-disulfide levels in dairy cattle with foot disease. This study aimed to determine dynamic thiol-disulfide levels in foot diseased and healthy dairy cattle. Demographic information about the animals, and clinical findings of foot diseases and lameness were presented. In the Foot Disease Group, native thiol (P<0.01), total thiol (P<0.05), disulfide (P<0.01), disulfide/native thiol (P<0.01) and disulfide/total thiol (P<0.01) results were found to be significantly higher than in the Control Group. Native thiol/total thiol (P<0.01) was found to be significantly higher in the Control Group than in the Foot Disease Group. As a result, statistically significant increases in thiol-disulfide levels were determined in foot diseased dairy cattle. It was shown that the thiol-disulfide balance was impaired. This study is the first to determine thiol-disulfide levels and thus changes in thiol-disulfide homeostasis in healthy and foot diseased dairy cattle. With further studies, oxidative stress changes that occur as a result of foot diseases can be better understood and the use of antioxidants as a part of treatment evaluated.
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Buda, Roberto, Francesco Di Caprio, Letizia Bedetti, Massimiliano Mosca, and Sandro Giannini. "Foot Overuse Diseases in Rock Climbing." Journal of the American Podiatric Medical Association 103, no. 2 (March 1, 2013): 113–20. http://dx.doi.org/10.7547/1030113.

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Background: Literature examining the incidence of foot diseases in rock climbing is limited to traumatic injuries. We examined a large sample of climbers, assessed the chronic diseases of the foot, and correlated them with foot morphology, shoe type, and type of climbing practiced. Methods: Between May 1 and September 30, 2009, 144 climbers (mean age, 31.7 years) were examined to analyze the effect of rock climbing on the various foot diseases found at the time of the evaluation. Results: Eighty-six percent of the climbers were affected by a pathologic condition. Nail disease was found in 65.3% of patients, followed by recurrent ankle sprains (27.8%), retrocalcaneal bursitis (19.4%), Achilles tendinitis (12.5%), metatarsalgia (12.5%), and plantar fasciitis (5.6%). Male sex, the use of high-type shoes, the high degree of climbing difficulty, and the competitive level were often related to the onset of foot diseases. Climbing shoes are usually smaller than common footwear. This “shoe-size reduction” averaged 2.3 sizes, forcing the foot into a supinated and cavus posture that favors lateral instability. The posterior edge of the shoe aperture produces increased pressure on the heel, with retrocalcaneal bursitis. Conclusions: Overuse foot diseases related to rock climbing are particularly frequent and debilitating. Detailed knowledge of these diseases and their predisposing factors may help us implement effective preventive or therapeutic measures, including changes in the type of climbing, correction of body weight, degree of difficulty, footwear, orthoses, and measures that maximize the support of the foot to the ground. (J Am Podiatr Med Assoc 103(2): 113–120, 2013)
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Garza, Blanca N., Veronica Ancona, Juan Enciso, Humberto L. Perotto-Baldivieso, Madhurababu Kunta, and Catherine Simpson. "Quantifying Citrus Tree Health Using True Color UAV Images." Remote Sensing 12, no. 1 (January 3, 2020): 170. http://dx.doi.org/10.3390/rs12010170.

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Huanglongbing (HLB) and Phytophthora foot and root rot are diseases that affect citrus production and profitability. The symptoms and physiological changes associated with these diseases are diagnosed through expensive and time-consuming field measurements. Unmanned aerial vehicles (UAVs) using red/green/blue (RGB, true color) imaging, may be an economic alternative to diagnose diseases. A methodology using a UAV with a RGB camera was developed to assess citrus health. The UAV was flown in April 2018 on a grapefruit field infected with HLB and foot rot. Ten trees were selected for each of the following disease classifications: (HLB-, foot rot–), (HLB+, foot rot–), (HLB-, foot rot+) (HLB+, foot rot+). Triangular greenness index (TGI) images were correlated with field measurements such as tree nutritional status, leaf area, SPAD (leaf greenness), foot rot disease severity and HLB. It was found that 61% of the TGI differences could be explained by Na, Fe, foot rot, Ca, and K. This study shows that diseased citrus trees can be monitored using UAVs equipped with RGB cameras, and that TGI can be used to explain subtle differences in tree health caused by multiple diseases.
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Jackson, Hilary. "Common cutaneous diseases of the canine foot." In Practice 21, no. 2 (February 1999): 54–61. http://dx.doi.org/10.1136/inpract.21.2.54.

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Katsambas, Andreas, and Christine Stefanaki. "Cutaneous diseases of the foot: unapproved treatments." Clinics in Dermatology 20, no. 6 (November 2002): 689–99. http://dx.doi.org/10.1016/s0738-081x(02)00291-2.

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Elkeles, R. S., and J. H. Wolfe. "ABC of vascular diseases. The diabetic foot." BMJ 303, no. 6809 (October 26, 1991): 1053–55. http://dx.doi.org/10.1136/bmj.303.6809.1053.

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Cohen, Stuart H. "Diabetic foot infections." Infectious Diseases Newsletter 5, no. 7 (July 1986): 52–54. http://dx.doi.org/10.1016/0278-2316(86)90037-x.

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Deka, Deepjyoti, Kushal K. Sarma, Jodumoni Kachari, Jiten Rajkhowa, N. N. Barman, Syed A. Arif, and T. Das. "Determinants of Equine Foot Diseases in Assam, India." Journal of Advances in Biology & Biotechnology 27, no. 5 (April 18, 2024): 525–34. http://dx.doi.org/10.9734/jabb/2024/v27i5815.

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Aim: Equine foot problems is crucial for maintaining the overall health and performance of horses, as these issues can significantly impact their mobility, comfort, and quality of life. A lot of studies have been conducted in these aspects, however, no such detail history have been reported from this part of the country. The present study deals with the prevalence of various foot disorders in riding horses and their correlation to the type of ration provided, work engagement and immediate environmental conditions like equine housing patterns. The study also tries to understand the correlations between the prevalence of diverse foot ailments and the temporal variations specific to the region. Study Design: A cross-sectional observational work designed to collect data regarding various foot affections prevalent in the equine population of selected locations of Assam, India. Place of Study:4th Assam Police Battalion, Kahilipara, North-East Police Academy, Barapani, 47 Assam NCC Squadron, Khanapara and SSB horse unit, Debendra Nagar, Tezpur. Methodology: Surveys were conducted to assess the prevalence of hoof-related conditions in horses through interviews, physical examinations and radiographic examinations. Etiological factors were investigated by recording the history of affected animals, including ration type, quantity, foot care practices. Results: Thirty-five (71.42%) exhibited various foot lesions while the remaining 14 horses were detected with minor cuts/abrasions. The Prevalence of foot afflictions was found to be higher during the summer (42.86%) in comparison to the winter (28.57%). The spectrum of foot ailments documented includes hoof overgrowth (57.14%), hoof cracks (20%), thrush (8.57%), suppurative sole conditions (5.71%), quittor (2.86%), laminitis (2.86%) and bulb fibromas (2.86%). The occurrences of various types of foot afflictions were elevated in equine enclosures with concrete flooring (94.29%), as opposed to sand flooring (5.71%). Hematological analyses indicated significant (P<0.05) alterations in various blood parameters during both summer and winter for both healthy and affected equines in Hb and mean values of Red blood cells (RBC) and White Blood cells (WBC) except for neutrophils. Biochemical assessments revealed an increase in mean values of serum creatinine, creatine kinase (CK) and alkaline phosphatase (ALP) in affected horses, though aspartate amino transferase (AST) levels remained unaffected. Conclusion: The multifaceted interplay between equine health, housing conditions, dietary patterns, and seasonal factors in the prevalence of foot disorders in stabled horses.
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Povsic, Thomas J., and Bernard J. Gersh. "Stem Cells in Cardiovascular Diseases: 30,000-Foot View." Cells 10, no. 3 (March 9, 2021): 600. http://dx.doi.org/10.3390/cells10030600.

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Stem cell and regenerative approaches that might rejuvenate the heart have immense intuitive appeal for the public and scientific communities. Hopes were fueled by initial findings from preclinical models that suggested that easily obtained bone marrow cells might have significant reparative capabilities; however, after initial encouraging pre-clinical and early clinical findings, the realities of clinical development have placed a damper on the field. Clinical trials were often designed to detect exceptionally large treatment effects with modest patient numbers with subsequent disappointing results. First generation approaches were likely overly simplistic and relied on a relatively primitive understanding of regenerative mechanisms and capabilities. Nonetheless, the field continues to move forward and novel cell derivatives, platforms, and cell/device combinations, coupled with a better understanding of the mechanisms that lead to regenerative capabilities in more primitive models and modifications in clinical trial design suggest a brighter future.
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Ko, Young Jin, and Hye Won Kim. "Diagnosis and Conservative Treatment of Common Foot Diseases." Journal of the Korean Medical Association 47, no. 3 (2004): 247. http://dx.doi.org/10.5124/jkma.2004.47.3.247.

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Dissertations / Theses on the topic "Foot diseases"

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Du, Toit Leon Lourens. "Form and function of the rheumatoid foot." Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/25632.

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Redmond, A. C. (Anthony C. ). "Foot posture in neuromuscular disease : development and evaluation of a novel method for quantifying change in foot posture using Charcot-Marie-Tooth disease as a clinical model." Phd thesis, Department of Paediatrics and Child Health, Faculty of Medicine, 2004. http://hdl.handle.net/2123/8077.

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Chen, Shih-Ping. "Epidemiology, pathogenesis and surveillance of pig adapted strain of foot and mouth disease in Taiwan /." Murdoch University Digital Theses Program, 2008. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20080813.104029.

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Hui, Kin-hi Raymond. "Molecular epidemiology of and vaccine development against foot-and-mouth disease virus in Hong Kong." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31548544.

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Sahle, Mesfin. "An epidemiological study on the genetic relationships of foot-and-mouth disease viruses in East Africa." Thesis, University of Pretoria, 2004. http://hdl.handle.net/2263/27222.

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Within East African countries many of the known infectious diseases of animals occur commonly and are poorly controlled. Foot-and-mouth disease (FMD) is one of the contagious viral diseases that has great impact on economic development both in terms of direct and indirect losses. The epidemiology of the disease is complex due to the presence of six of the seven serotypes and the presence of large numbers of both wild and domestic susceptible animals in the region. Decision-making to determine the importance of FMD control relative to the economic consequences and what FMD control strategies should be applied based on the epidemiological information is required. In this regard the first step is to investigate the genetic relationships/variability of East African isolates and their phylogeographic distribution. These can provide base-line information for designing control strategies by vaccination as well as the determination of the sources of infection. Sufficient genetic information on the FMO serotypes O, SAT-1 and SAT-2 are lacking and therefore the number of viral Iineages and genotypes or topotypes from East African countries could not be determined. Published studies on the relative occurrence and genotype distribution of FMO are largely confined to the southern and western part of the continent. In this study, the genetic profile of the 3 most prevalent serotypes (0, SAT-2 and SAT-1) recovered from outbreaks in East Africa between 1957 and 2003 was addressed. Phylogenetic analysis of partial and complete sequences of the 10 gene revealed the presence of distinct lineages and genotypes for East Africa as well as historical relationships of some of the genotypes with isolates from other regions. A great variation in the occurrence and distribution of these serotypes were found. All the African and the Middle East/South East Asian isolates of serotype O included in this study clustered into one lineage having 8 distinct topotypes. These results indicated that between countries as well as inter-regional (east and west Africa) spread of viruses occurred in the past. Inter-regional spread of the virus between eastern Africa and western Africa was also confirmed for SAT-1 viruses. The fact that phylogenetic links are found with both serotypes implies that the spread of viruses was possibly associated with unrestricted animal movement due to nomadic movement in Africa. The phylogenetic relationships of SAT-1 viruses are more diversified in Africa. Eight lineages and 11 genotypes were identified when the optimal nucleotide sequence differences of ≥ 23% for lineages and ≥ 6% for genotypes were used as a cut-off values. It was observed that viruses from Uganda are evolving independently from viruses elsewhere on the continent and clustered into 3 discrete lineages. In contrast, viruses from countries neighbouring Uganda, Kenya and Tanzania, clustered into one lineage. Uganda also harboured 3 topotypes of SAT-2 virus isolates, one is distinct for Uganda and the other are shared with Kenya and Zaire (DRC). This study highlighted distinct lineages found in Uganda and needs further investigation. Within SAT-2, 67 isolates from 22 African countries and Saudi Arabia clustered into 5 lineages which consisted of 15 genotypes. Clustering of viruses into distinct genotypes (topotypes) according to year of isolation and geographical origin was observed showing countries with common boundaries shared common epizootics in the past. These results also showed a link between eastern and southern African countries. Attempts were also made to investigate the incidence of FMD in Ethiopia using sera collected from cattle, small ruminants and wildlife. The results obtained from the liquid phase blocking ELISA and the 3ABC ELISA indicated the presence of SAT-1 and SAT-2 in buffalo populations in the southern part of Ethiopia while results from small ruminants and other wildlife were not indicative of any significant role in the epidemiology of FMD. Serological results also indicated that SAT-1 is present in cattle, although this serotype has not been previously identified. The cumulative molecular epidemiological results from this and previous studies indicated that genetic variability of FMD viruses can be independently maintained within country/countries or regions as well as inter-regions of Africa. The serological results from buffaloes in East Africa are also suggestive of a possible reservoir of the SAT types FMD in the region which has a great impact on the control of the disease. Furthermore, the numerous lineages and genotypes of FMD virus isolates in Africa having distinct or overlapping distributions as well as the genetic linkage between regions will complicate the epidemiology of the disease. Therefore, it is strategically important to consider a regional approach and the use of a vaccine which contains a cocktails of antigens of FMD virus strains.
Thesis (PhD)--University of Pretoria, 2004.
Veterinary Tropical Diseases
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Lau, Ming-ho, and 劉明昊. "Risk factors of hand foot mouth diseases outbreaks in kindergartens inHong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42994901.

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Halleen, Francois. "Characterisation of Cylindrocarpon spp. associated with black foot disease of grapevine." Thesis, Stellenbosch : Stellenbosch University, 2005. http://hdl.handle.net/10019.1/21454.

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Dissertation (PhD (Agric))--University of Stellenbosch, 2005.
ENGLISH ABSTRACT: During the past few years a drastic reduction has been noted in the survival rate of grafted grapevines in nurseries, as well as in young vineyards in the Western Cape Province of South Africa. Circumstantial evidence suggested that Cylindrocarpon spp., which cause black foot disease of grapevine, were associated with this decline. Black foot disease of grapevine is a relatively new, and as yet poorly known disease affecting vines in various countries where grapevines are cultivated. Primary aims of this research have been (1) to conduct nursery surveys in order to determine which fungi are involved in the decline phenomenon, with special reference to the involvement of Cylindrocarpon spp., (2) to identify and characterise the organisms believed to be the causal organisms of black foot disease, and (3) the development of control and/or management strategies to prevent or eradicate Cylindrocarpon infections. Nursery grapevines were sampled at different stages from three commercial nurseries in the Wellington area of the Western Cape Province and were investigated during the 19992000 season by means of destructive sampling. The first samples were taken in September from callused cuttings prior to planting in nurseries. After planting, asymptomatic rooted cuttings were selected from nurseries after 3, 6 and 9 months. Isolation studies clearly demonstrated that different “Cylindrocarpon spp.” infected cuttings from nursery soils. These species rarely occurred in rootstock propagation material prior to planting. At the time of planting, the susceptible basal ends (especially the pith area) of most of the nursery cuttings are partly or even fully exposed. Callus roots also break during the planting process, resulting in small wounds susceptible to infection by soilborne pathogens. The isolation studies revealed that the first infections occurred in the roots, followed by infections of the rootstocks. These infections increased progressively during the course of the growing season. Substantial variation in cultural and morphological characters was observed among the Cylindrocarpon isolates obtained from the nursery survey, as well as from isolations that were made from diseased grapevines. Morphological and phylogenetic studies were conducted to identify these “Cylindrocarpon spp.” and to establish their association with black foot disease. Sequences of the partial nuclear large subunit ribosomal DNA (LSU rDNA), internal transcribed spacers 1 and 2 of the rDNA including the 5.8S rDNA gene (ITS), and partial β-tubulin gene introns and exons were used for phylogenetic inference. Phylogenetic analyses confirmed the diversity observed among the isolates and four Cylindrocarpon-like species were identified. One of these species was initially identified as Cylindrocarpon destructans. However, further research revealed C. destructans to represent a species complex. Grapevine isolates of “C. destructans” proved to be identical to the ex-type strain of Cylindrocarpon liriodendri, which also produced a teleomorph, Neonectria liriodendri in culture. A second species was newly described in this study as Cylindrocarpon macrodidymum (Neonectria macrodidyma). The two remaining Cylindrocarpon-like species were placed in a new genus, Campylocarpon. The two species were named Campylocarpon fasciculare and Campylocarpon pseudofasciculare. Pathogenicity studies confirmed that all four species were able to reduce root and shoot mass significantly. Knowledge obtained pertaining to the disease cycle of black foot disease suggest that suitable management strategies should focus on prevention of primary infection in nurseries. However, at present, no fungicides are registered for control of this disease in South African vineyards or nurseries. Thirteen fungicides were screened in vitro for mycelial inhibition of these pathogens. Prochloraz manganese chloride, benomyl, flusilazole and imazalil were the most effective fungicides tested, and were subsequently included in semi-commercial field trials. Basal ends of grafted cuttings were dipped (1 min) in various chemical and biological treatments prior to planting in open-rooted nurseries. Black foot pathogens were not isolated from grafted cuttings prior to planting in nurseries. Additional treatments involved soil amendments with Trichoderma formulations and hot water treatment (50°C for 30 min) of dormant nursery grapevines. Field trials were evaluated after a growing season of eight months. The incidence of black foot pathogens was not significantly and/or consistently reduced by the majority of chemical or biological treatments. However, these pathogens were not isolated from uprooted plants that were subjected to hot water treatment. It is therefore recommended that hot water treatment of dormant nursery plants be included in an integrated strategy for the proactive management of black foot disease in grapevine nurseries.
AFRIKAANSE OPSOMMING: Gedurende die afgelope paar jaar is ‘n drastiese afname waargeneem in die sukses van geënte wingerdplante in kwekerye, sowel as jong wingerde van die Wes-Kaap. Omstandigheidsgetuienis dui daarop dat Cylindrocarpon spp., wat die wingerdsiekte swartvoet veroorsaak, geassosieer word met hierdie agteruitgang. Swartvoet is ‘n relatiewe nuwe siekte waarvan daar baie min inligting bekend is, alhoewel dit voorkom in verskeie lande waar wingerd verbou word. Die primêre doel van navorsing was (1) om opnames in wingerdkwekerye uit voer om te bepaal watter swamme betrokke is by die verskynsel van agteruitgang, met spesiale verwysing na die betrokkenheid van Cylindrocarpon spp., (2) om die organismes te identifiseer en te karakteriseer wat daarvan verdink word dat hulle die siekte swartvoet veroorsaak, en (3) om beheer en/of bestuurspraktyke te ontwikkel om Cylindrocarpon infeksies te voorkom of uit te wis. Kwekeryplantjies in drie kommersiële kwekerye in die Wellington omgewing van die Wes-Kaap is gedurende verskillende tye gedurende die groeiseisoen gemonitor. Die opnames het plaasgevind gedurende die 19992000 seisoen deur middel van destruktiewe monsterneming. Die eerste monsters is geneem in September nadat die stokkies geënt en gekallus is en voordat dit in die kwekery geplant is. Na plant is asimptomatiese, gewortelde plante vanuit die kwekerye na 3, 6 en 9 maande uitgehaal. Isolasiestudies dui duidelik daarop dat verskillende “Cylindrocarpon spp.” plante vanuit die kwekerygrond geïnfekteer het. Hierdie spesies het selde voorgekom in onderstok-voortplantingsmateriaal voor plant. Tydens plant is die vatbare basale gedeelte, veral die pit, van die meeste geënte stokkies gedeeltelik of selfs volledig blootgestel. Kalluswortels breek ook tydens plant wat wonde laat vir infeksie deur grondgedraagde siektes. Die isolasiestudies dui ook daarop dat die eerste infeksies in die wortels plaasgevind het, gevolg deur infeksies van die onderstokke. Hierdie infeksies het toenemend voorgekom gedurende die verloop van die groeiseisoen. Substansiële variasie in kultuur- en morfologiese eienskappe is waargeneem in die Cylindrocarpon isolate wat tydens die kwekeryopnames versamel is, sowel as van isolasies wat gemaak is uit siek plante. Morfologiese en filogenetiese studies is uitgevoer om hierdie “Cylindrocarpon spp.” te identifiseer en hul betrokkenheid by die siekte swartvoet uit te klaar. Gedeeltelike DNS volgordes van die groot ribosomale subeenheid (“LSU rDNA”), interne getranskribeerde spasiëerderarea (“ITS1, “ITS2”), insluitend die 5.8S rRNS geen, en gedeeltelike β-tubilien geen introns and eksons is gebruik vir filogenetiese analise. Filogenetiese analises het die diversiteit wat waargeneem is tussen die verskillende isolate bevestig deurdat vier Cylindrocarpon-agtige spesies geïdentifiseer is. Een van hierdie spesies is aanvanklik geïdentifiseer as Cylindrocarpon destructans. Verdere navorsing het egter daarop gedui dat C. destructans ‘n spesie-kompleks verteenwoordig. “C. destructans” afkomstig van wingerd blyk identies te wees aan die ex-tipe isolaat van Cylindrocarpon liriodendri, wat ook ’n teleomorf, Neonectria liriodendri in kultuur vorm. ’n Tweede spesie is nuut beskryf in hierdie studie as Cylindrocarpon macrodidymum (Neonectria macrodidyma). Die twee oorblywende Cylindrocarpon-agtige spesies is geplaas in ‘n nuwe genus, Campylocarpon. Die twee spesies staan bekend as Campylocarpon fasciculare en Campylocarpon pseudofasciculare. Patogenisiteitstudies het bevestig dat al vier spesies die vermoë het om wortel- en lootmassa van wingerdplant drasties te verlaag. Kennis wat opgedoen is rakende die lewensiklus van swartvoet dui daarop dat bestuurspraktyke daarop moet fokus om primêre infeksies in wingerdkwekerye te voorkom. Op die oomblik is daar egter geen fungisiedes geregistreer vir die beheer van die siekte in Suid- Afrikaanse wingerde of kwekerye nie. Dertien fungisiedes is in vitro geëvalueer om te bepaal of dit miseliumgroei van hierdie swamme kan inhibeer. Prochloraz mangaan chloried, benomyl, flusilasool en imazalil was die effektiefste fungisiedes wat ondersoek is, en is gevolglik ingesluit in semi-kommersiële veldproewe. Die basale gedeelte van geënte stokkies is gedoop (1 min) in verskeie chemies en biologiese behandelings voordat dit geplant is in die kwekerye. Patogene wat geassosieer word met swartvoet is nie vanuit geënte stokkies geïsoleer voordat dit in die kwekerye geplant is nie. Addisionele behandelings het bestaan uit grondtoevoegings met Trichoderma formulasies, sowel as warmwaterbehandeling (50°C vir 30 min) van dormante kwekeryplante. Die veldproewe is geëvalueer na ‘n groeiseisoen van 8 maande. Die voorkoms van swartvoet patogene is nie betekenisvol/konstant verlaag deur die meeste chemies en biologiese behandelings nie. Hierdie patogene is egter nie vanuit plante geïsoleer wat na uithaal aan warmwaterbehandeling blootgestel is nie. Dit word dus aanbeveel dat warmwaterbehandeling van dormante kwekeryplante deel word van ‘n geïntegreerde strategie vir die pro-aktiewe beheer van swartvoet in wingerdkwekerye.
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Knight-Jones, Theo. "Field evaluation of foot-and-mouth disease vaccination in Turkey." Thesis, Royal Veterinary College (University of London), 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618321.

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Lau, Ming-ho. "Risk factors of hand foot mouth diseases outbreaks in kindergartens in Hong Kong." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42994901.

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Biswal, Jitendra Kumar. "Evaluation of mucosal immunity in FMDV vaccinated and infected cattle." Thesis, Royal Veterinary College (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572448.

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Books on the topic "Foot diseases"

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Jie, Li, ed. Foot therapy for common diseases. 2nd ed. Beijing: Foreign Languages Press, 2009.

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Tachdjian, Mihran O. The child's foot. Philadelphia: Saunders, 1985.

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Maloy, Otis C. Foot rot of wheat. Pullman, [Wash.]: Cooperative Extension, College of Agriculture and Home Economics, Washington State University, 1986.

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Aging, National Institute on, ed. Foot care. [Bethesda, Md.]: National Institutes on Aging, 2000.

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Aziz, Nather, ed. Diabetic foot problems. Hackensack, N.J: World Scientific, 2008.

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1924-, Levin Marvin E., and O'Neal Lawrence W. 1923-, eds. The Diabetic foot. 4th ed. St. Louis: Mosby, 1988.

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Christman, Robert A. Foot and ankle radiology. St. Louis, Mo: Churchill Livingstone, 2003.

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Barrett, Stephen L., and John Tassone. Diagnostic ultrasound of the foot and ankle. Brooklandville, Md: Data Trace Pub. Co., 2013.

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R, Luces José, ed. A Color atlas of foot disorders. Mount Kisco, NY: Futura Pub. Co., 1990.

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Aziz, Nather, ed. Diabetic foot problems. Hackensack, N.J: World Scientific, 2008.

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Book chapters on the topic "Foot diseases"

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Dukes, Brittany, and Lorenzo Gamez. "Frankenstein Foot." In Unusual Diseases with Common Symptoms, 173–82. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58952-7_18.

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Grainger, Andrew J. "Imaging the Foot." In Musculoskeletal Diseases 2017-2020, 17–24. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-54018-4_2.

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El-Khoury, George Y., and Jeremy J. Kaye. "Ankle and Foot." In Musculoskeletal Diseases 2009–2012, 49–56. Milano: Springer Milan, 2009. http://dx.doi.org/10.1007/978-88-470-1378-0_9.

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Costa, Rafael Henrique Rodrigues, Ligia de Loiola Cisneros, and Alessandra Rocha Luz. "Diabetic Foot." In Vascular Diseases for the Non-Specialist, 151–65. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-46059-8_13.

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Diehm, Curt, Jens-Rainer Allenberg, Keiko Nimura-Eckert, and Frank J. Veith. "Diabetic Foot Syndrome." In Color Atlas of Vascular Diseases, 181–201. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-06287-6_7.

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Rosenberg, Z. S., and M. Zanetti. "Imaging of the Foot and Ankle." In Musculoskeletal Diseases, 39–47. Milano: Springer Milan, 2005. http://dx.doi.org/10.1007/88-470-0339-3_7.

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Basu, Anupam. "Foot and Ankle." In Diagnostic Radiology of the Rheumatic Diseases, 57–72. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-25116-1_5.

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Grace, Delia, Tadelle Dessie, Michel Dione, Henry Kiara, Anne Liljander, Jeff Mariner, Jan Naessens, et al. "Transboundary animal diseases." In The impact of the International Livestock Research Institute, 274–301. Wallingford: CABI, 2020. http://dx.doi.org/10.1079/9781789241853.0274.

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Abstract Transboundary animal diseases (TADs) are highly contagious epidemics with the potential for very rapid spread, causing serious economic and sometimes public health consequences while threatening farmers' livelihoods. TADs often cause high morbidity and mortality in susceptible animal populations. Some TADs are also emerging infectious diseases, food-borne diseases and/or zoonoses: these are covered in other chapters. This chapter covers those high-impact, highly contagious animal diseases, such as foot-andmouth disease (FMD), that do not infect humans but do affect food and nutrition security and trade that the International Livestock Research Institute (ILRI) has been working on since the 1990s. These are: African swine fever (ASF), mycoplasma disease (both contagious bovine pleuropneumonia (CBPP) and contagious caprine pleuropneumonia (CCPP)), peste des petits ruminants (PPR) and Newcastle disease (ND). Other TADs, which were to a lesser degree the focus of ILRI research, are briefly mentioned (including FMD, classical swine fever (CSF) and rinderpest).
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Zaidi, Zohra, Khalid Hussain, and Simi Sudhakaran. "Management of the Diabetic Foot." In Treatment of Skin Diseases, 503–5. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-89581-9_41.

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Nagaratnam, Nages, Kujan Nagaratnam, and Gary Cheuk. "Chronic Leg and Foot Ulcers in the Elderly." In Geriatric Diseases, 1–6. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-32700-6_87-1.

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Conference papers on the topic "Foot diseases"

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Mohseni, Kamran. "A Steerable Mechanism for Wireless Capsule Endoscopy." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38048.

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Gastrointestinal (GI) disease affects millions of people worldwide and costs billions of dollars annually. Because the symptoms of GI diseases are often vague, physicians are often presented with gastrointestinal disease in advanced stages. Because conventional endoscopes often cannot reach all the way through the 20-foot small bowel, exploratory surgery previously was necessary to enable physicians to complete their diagnosis.
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Patuwondatu, Martini Heniastaty, and icilya Candi. "Effects of Foot Reflexology Massage on Reducing Blood Pressure in Elderly with Hypertension at Sekupang Public Health Center, Batam." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.05.21.

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ABSTRACT Background: Hypertension is significantly associated with increased morbidity and mortality of cerebrovascular diseases, myocardial infarction, congestive heart failure and renal insufficiency. Hypertension is a major public health problem and an important research area due to its high prevalence and a major risk factor for cardiovascular disease and other complications. This study aimed to determine the effect of foot reflexology therapy on lowering blood pressure in elderly people suffering from hypertension in the working area of Sekupang community health center, Batam City. Subjects and Method: This study was an experiment with a pretest – posttest control group design. A sample of 15 elderlies was selected by simple random probability sampling. The dependent variable was elderly with hypertension. The independent variable was foot reflexology therapy. The data obtained from this study were the values of pre and post therapy blood pressure between the control group and the treatment group. The data was analyzed by Wilcoxon test. Results: After the intervention of foot reflexology was carried out, foot reflexology affected reducing headache intensity (Mean= 2; SD= 0.52) and it was statistically significant (p= 0.002). When compared to the control group that was not given therapy, indicating that pain intensity tended to increase with statistical results (Mean = 2.33; SD= 0.69) obtained (Z score = -2.64) with p = 0.008. Conclusion: Reducing the intensity of headaches and able to lower blood pressure in older people with hypertension. Keywords: Hypertension, Foot Reflexology, Elderly, Headache Correspondence: Martini Heniastaty Patuwondatu. Faculty of Public Health, Universitas Indonesia. Email : martha.imbuh@gmail.com. 081277466363 DOI: https://doi.org/10.26911/the7thicph.05.21
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Jia, Wenxiao, Xiang Li, Kewei Tan, and Guotong Xie. "Predicting the outbreak of the hand-foot-mouth diseases in China using recurrent neural network." In 2019 IEEE International Conference on Healthcare Informatics (ICHI). IEEE, 2019. http://dx.doi.org/10.1109/ichi.2019.8904736.

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Suresh, KS, and A. Sukesh Kumar. "Multi Signal Pulse Wave Analysis for the Identification of Vascular Diseases Leading to Diabetic Foot." In 2021 IEEE Second International Conference on Control, Measurement and Instrumentation (CMI). IEEE, 2021. http://dx.doi.org/10.1109/cmi50323.2021.9362797.

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Miyake, Shin-Ichiro, and Masao Arakawa. "Approximate Multi-Objective Optimization of Medical Foot Support." In ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/detc2008-49937.

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Splayfoot seems not serious diseases. However, it cause fatigue in the daily life. It makes breakthrough in track athletic and many other fields in sports. In that sense, if we can solve these problems it might support daily life much comfortable especially for elder people. To support splayfoot, there are some commercial ones. But they just add small amount of support and not made up for each person. Besides, when the height of support is not suitable for patients, it sometimes make situation worse. We have tried it and measured by using myoelectric potential measurement, and see differences of three patients. Even if we use the same commercial support its effectiveness differs to each other and sometimes it make worse. Physical therapists make foot support for each patient but they make them owing to their experience. There are studies on the positions of bone of foot and its portrait of the desired positions has been reported by medical doctors. One of them is called Mizuno [1973] standard. In this study, we tried to design foot support aiming to make portrait of this standard. For that purpose, we use approximate multi-objective optimization using Radial Basis Function network. First, we make some support and try to find characteristic points of spline function. These processes have been measured by X-ray and calculated portraits for each X-ray digital image. Then, we have gone through multi-objective optimization and design a foot support for one patient and made it by hard sponge. We measured it by X-ray again to make sure that the portrait has been done in acceptable position. For validation, we use electromyography again. As a result the foot support by the proposed method shows the maximum reduction in integral of myoelastic. This shows the effectiveness of the proposed method.
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Zhang, Xiaoming, and James F. Greenleaf. "Measurement of the Propagation Velocity of Pulse Wave Generated by Ultrasound in Arteries." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-79619.

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Arterial wall stiffness can be associated with various diseases. The stiffness of an artery can be assessed by measurement of the pulse wave velocity (PWV). Usually, PWV is estimated using the foot-to-foot method. However, the foot of the pressure wave is not very clear due to reflected waves. Also, the blood pressure wave generated by the heart is normally a low frequency wave, hence the time resolution is low. PWV is an average indicator of artery stiffness between two measuring locations, therefore, it is not easy to identify local stiffness. In this paper a short external pulse is generated in an artery by the radiation force of ultrasound. The propagation velocity of the pulse wave is measured along the artery. The temporal resolution of this method, which is in the range of microseconds, is much higher than the conventional pressure PWV method, and therefore allows the wave velocity to be measured accurately over a few millimeters.
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Sandamali, J. A. N., T. D. H. R. Madushani, and H. A. R. P. Perera. "Importance of Selected Tuber Crops for Cultivation in Sri Lanka – A Systematic Review." In 4th International Conference on Agriculture, Food Security and Safety. iConferences (Pvt) Ltd, 2024. http://dx.doi.org/10.32789/agrofood.2023.1002.

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Abstract: Food security is a major concern in today’s context which encompasses availability, affordability, and nutritional quality of food for the population. In Sri Lanka, around 55 traditional and indigenous yams and tuber crop species were identified, and they grow in almost everywhere in the country. Tubers are in a wider range of cultivars, and it is characterized by increased adoptability to different agroecological zones. Convenience propagation methods, wider adoptability, rich in carbohydrates, and less vulnerability to pests and diseases are vital features in promoting tuber crops to supplement main courses in human diet. This research attempt to review of nutritional and agricultural value of five selected tuber crop species as follows: Elephant foot yam (Amorphophallus paenoiifolius), three Rajala species (Dioscorea alata, Dioscorea bulbifera, Dioscorea sativa), and Arrowroot (Maranta arundinacea). Data was gathered from relevant textbooks and electronic databases include PubMed, Scopus, Google Scholar, and Journals following the PRISMA model. Traditional root and tuber crops are identified as a rich source of carbohydrates, energy, minerals, vitamins, pharmacological properties, bioactive compounds, and with relatively convenient in cultivation in a wider spectrum of agroecological zones. It is easy to cultivate, and they can grow even in unfavorable harsh climate conditions. It is required relatively less agricultural input and can gain more income and output. Inclusiveness of the selected crops into main meals would increase the diversity of the food intake and helps food security. Make aware of those yams among public is also beneficial as they have good amount of carbohydrate, fibers and many pharmacological properties which relieves diseases as well. Keywords: Food, Tuber, Sri Lanka, Nutritional, Agricultural
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Miyake, Shin-ichiro, Suguru Nakao, and Masao Arakawa. "Approximate Multi-Objective Optimization of Medical Foot Support: Case of 3D Shape Optimization." In ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/detc2009-87090.

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Splayfoot seems not serious diseases. However, it cause fatigue in the daily life. In that sense, if we can solve these problems it might support daily life much comfortable especially for elder people. To support splayfoot, there are some commercial ones. But they just add small amount of support and not made up for each person. Besides, when the height of support is not suitable for patients, it sometimes makes situation worse. We have tried it and measured by using myoelectric potential measurements, and see differences of three patients. Even if we use the same commercial support its effectiveness differs to each other and sometimes it makes worse. Physical therapists make foot support for each patient but they make them owing to their experience. There are studies on the positions of bone of foot and its portrait of the desired positions has been reported by medical doctors. One of them is called Mizuno standard [1]. In the previous study, we tried to design foot support aiming to make portrait of this standard in vertical space. For that purpose, we used approximate multi-objective optimization using Radial Basis Function network. For validation, we used electromyography again. As a result the foot support by the proposed method showed the maximum reduction in integral of myoelectric. However, in the previous study [2], we only used two design variables, and we have only designed vertical phase. Therefore, we have not completely designed the support. In this study, we use 3D spline expression to make support, and try to design 3D shape of support. In validation, the results of approximate multi-objective optimization show the best reduction in integral of myoelectric, and show the effectiveness of the proposed method.
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Amerinatanzi, Amirhesam, Hashem Zamanian, Narges Shayesteh Moghaddam, Hamdy Ibrahim, Mohamed Samir Hefzy, and Mohammad Elahinia. "On the Advantages of Superelastic NiTi in Ankle Foot Orthoses." In ASME 2016 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/smasis2016-9267.

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Foot drop usually happens due to neurological and muscular diseases. It limits individuals’ abilities in ankle and toe represented in dorsiflexion during swing phase, and plantar flexion during heel strike. A non-surgical solution to such weakness is the use of ankle foot orthoses (AFOs) which can assist in such abnormal ambulation. The purpose of this work is to develop a new ankle foot orthosis that helps patients to have more normal ankle joint behavior. The proposed AFO device takes advantage of the superelastic behavior of Ni-rich NiTi alloys. In order to evaluate the performance of the Ni-rich NiTi hinged ankle foot orthoses, several motion analysis tests for a normal walking of a healthy subject were conducted. Also, a finite element model were developed to evaluate the performance of superelastic versus stainless steel springs. A Ni-rich NiTi wire was wrapped around a designed rod and the two heads were fixed to the rod (to get the shape of a spring). Then a heat treatment process was performed in a furnace to shape set the NiTi wires and to provide them with the needed superelastic behavior. The produced springs were connected to a designed hinged ankle foot orthoses. Motion analysis was performed on a healthy subject during normal walking in the case of using conventional stainless steel springs, and with using the produced NiTi springs. Joint kinematics and kinetics data of left lower limb (which was equipped with the AFO brace) were collected and calculated to compare normal walking patterns to the resultant walking patterns with the proposed ankle foot orthosis. The CAD file of the AFO, hinge structure and the springs were developed. Each component was meshed and the convergence study were conducted. A finite element model was developed after assembling and introducing all the interactions between parts in Abaqus. The boundary conditions were applied to the system in a way simulating normal walking conditions. Different material properties (stainless steel and superelastic NiTi) were assigned to the springs in the model to evaluate the performance of the system under the aforementioned loading scenario. The results of the motion analysis on a healthy subject during walking indicate that the use of the superelastic NiTi springs causes more normal walk compare to the use of the conventional stainless steel springs, especially during swing phase and heel strike. Moreover, the ankle has closer stiffness profile to the normal walking in the case of using NiTi springs. The results of the finite element analysis show that the super elastic behavior of NiTi results in more hinge rotation while the stress concentration developed on the springs is within the safe levels and cannot cause failure of the NiTi springs. Motion analysis and finite element models were conducted for the proposed hinged AFO and the results were compared with conventional AFO. By taking advantage of the super elastic characteristic of NiTi, more normal walking behavior was observed in the case of using the proposed AFO with Ni-rich NiTi springs.
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Domingos, Francine de Paula Roberto, Sayuri Aparecida Hirayama, Rafael de Almeida, Lucas Silva Dias, Paulo Henrique Martinelli Oliveira, Raderi Luiz Cardoso dos Santos, Larissa Miyashiro, Lorena Dias de Araújo, and Gustavo Carvalho Costa. "Dync1h1 mutation in a patient with multiple neurological conditions." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.453.

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Introduction: Mutations in the cytoplasmic dynein 1 heavy chain 1 gene (DYNC1H1) were first described in 2010 related to dominant lower extremitypredominant spinal muscular amyotrophy (SMA) 1 and after to Charcot-MarieTooth (CMT) disease, neurodevelopmental disorders, central nervous system malformations and hereditary spastic paraplegia. The aim this case report intends to show a recent known genetic mutation that can be related to two different conditions simultaneously — CMT and SMA. Case report: F.R.S, male, 49 years old, noticed proximal left hemiparesis in his childhood; he started walking late and had a lot of falls as a child. Cognitive development was normal. The motor deficit progressed to a right hemiparesis at the age of 39 years old. Deficit progression was noticed because he had difficulty to go up and down stairs. Non-consanguineous parents, family history positive for physical disability of unknown cause. Neurological examination evidenced cavus foot, amyotrophy and tetraparesis with distal predominance of the lower limbs. Electroneuromyography was compatible with progressive proximal SMA. Thoracic and cervical magnetic resonance imaging showed syringomyelia and Chiari malformation (CM) type 1. Gene panel was compatible with DYNC1H mutation. Discussion: It is well known DYNC1H1 mutation relation to CMT and SMA, but this case had some different conditions rarely described that also could be investigated to be related to this gene mutation as CM type 1 and syringomyelia. Conclusion: The gene mutation identification is important to physician to promote recognition of multiple associated conditions. Until now, there is no treatment for the described conditions, but eventually, it could change and neurologists must be prepared to look for multiple diseases related to specific genetic condition.
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Reports on the topic "Foot diseases"

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Thanda Kyaw, Ai. Socio-Economic Impacts of Foot and Mouth Disease Among Cattle Farmers in Sagaing and Mandalay Areas, Myanmar. O.I.E (World Organisation for Animal Health), May 2014. http://dx.doi.org/10.20506/standz.2784.

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The World Organisation for Animal Health (OIE) Sub-Regional Representation for South East Asia (OIE SRR-SEA) implemented the Stop Transboundary Animal Diseases and Zoonoses (STANDZ) Programme funded by AusAID to strengthen the veterinary services and effectively manage the control and eradication of foot and mouth disease (FMD) in Cambodia, Lao PDR and Myanmar. The purpose of the study is to understand how FMD outbreaks impact smallholder farmers, both men and women, at the household and village level and how control and eradication of FMD would benefit them. Specific aims are to estimate the direct and indirect socio-economic costs associated with the outbreaks of FMD as well as of the measures taken by farmers to deal with such outbreaks and to identify issues that contributed to the socio-economic impacts of FMD outbreaks and opportunities to reduce them.
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Tang, Jiqin, Gong Zhang, Jinxiao Xing, Ying Yu, and Tao Han. Network Meta-analysis of Heat-clearing and Detoxifying Oral Liquid of Chinese Medicines in Treatment of Children’s Hand-foot-mouth Disease:a protocol for systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2022. http://dx.doi.org/10.37766/inplasy2022.1.0032.

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Review question / Objective: The type of study was clinical randomized controlled trial (RCT). The object of study is the patients with HFMD. There is no limit to gender and race. In the case of clear diagnosis standard, curative effect judgment standard and consistent baseline treatment, the experimental group was treated with pure oral liquid of traditional Chinese medicine(A: Fuganlin oral liquid, B: huangzhihua oral liquid, C: Lanqin oral liquid, D: antiviral oral liquid, E: Huangqin oral liquid, F: Pudilan oral liquid, G: Shuanghuanglian oral liquid.)and the control group was treated with ribavirin or any oral liquid of traditional Chinese medicine. The data were extracted by two researchers independently, cross checked and reviewed according to the pre-determined tables. The data extraction content is (1) Basic information (including the first author, published journal and year, research topic). (2) Relevant information (including number of cases, total number of cases, gender, age, intervention measures, course of treatment of the experimental group and the control group in the literature). (3) Design type and quality evaluation information of the included literature. (4) Outcome measures (effective rate, healing time of oral ulcer, regression time of hand and foot rash, regression time of fever, adverse reactions.). The seven traditional Chinese medicine oral liquids are comparable in clinical practice, but their actual clinical efficacy is lack of evidence-based basis. Therefore, the purpose of this study is to use the network meta-analysis method to integrate the clinical relevant evidence of direct and indirect comparative relationship, to make quantitative comprehensive statistical analysis and sequencing of different oral liquid of traditional Chinese medicine with the same evidence body for the treatment of the disease, and then to explore the advantages and disadvantages of the efficacy and safety of different oral liquid of traditional Chinese medicine to get the best treatment plan, so as to provide reference value and evidence-based medicine evidence for clinical optimization of drug selection. Condition being studied: Hand foot mouth disease (HFMD) is a common infectious disease in pediatrics caused by a variety of enteroviruses. Its clinical manifestations are mainly characterized by persistent fever, hand foot rash, oral herpes, ulcers, etc. Because it is often found in preschool children, its immune system development is not perfect, so it is very vulnerable to infection by pathogens and epidemic diseases, resulting in rapid progress of the disease. A few patients will also have neurogenic pulmonary edema Meningitis, myocarditis and other serious complications even lead to death, so effectively improve the cure rate, shorten the course of disease, prevent the deterioration of the disease as the focus of the study. In recent years, traditional Chinese medicine has played an important role in the research of antiviral treatment. Many clinical practices have confirmed that oral liquid of traditional Chinese medicine can effectively play the role of antiviral and improve the body's immunity.
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Hullinger, P. New England Foot and Mouth Disease Tabletop Exercise. Office of Scientific and Technical Information (OSTI), September 2008. http://dx.doi.org/10.2172/945849.

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Frieson, Kate Grace. A Gender Assessment of SEACFMD 2020: A Roadmap to Prevent, Control and Eradicate foot and mouth disease (by 2020) in Southeast Asia and China. O.I.E (World Organisation for Animal Health), December 2013. http://dx.doi.org/10.20506/standz.2785.

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This gender assessment of SEACFMD 2020: A Roadmap to Prevent, Control and Eradicate foot and mouth disease (by 2020) in Southeast Asia and China, responds to the requirement of AusAID that all strategies affecting human health, food security and poverty alleviation incorporate a gender perspective as women are not often included in the technical and community based aspects of programs relating to animal health and disease control. Gender roles and responsibilities affect women’s and men’s ability and incentive to participate in FMD roadmap activities, and can potentially lead to different project impacts for men and women.
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White, P. Scott, and Alina Deshpande. Agriculture and Food Security: Plant Disease Surveillance. Office of Scientific and Technical Information (OSTI), August 2012. http://dx.doi.org/10.2172/1049985.

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Grubman, Marvin J., Yehuda Stram, Peter W. Mason, and Hagai Yadin. Development of an Empty Viral Capsid Vaccine against Foot and Mouth Disease. United States Department of Agriculture, August 1995. http://dx.doi.org/10.32747/1995.7570568.bard.

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Foot-and-mouth disease (FMD), a highly infectious viral disease of cloven-hoofed animals, is economically the most important disease of domestic animals. Although inactivated FMD vaccines have been succesfully used as part of comprehensive eradication programs in Western Europe, there are a number of concerns about their safety. In this proposal, we have attempted to develop a new generation of FMD vaccines that addresses these concerns. Specifically we have cloned the region of the viral genome coding for the structural proteins and the proteinase responsible for processing of the structural protein precursor into both a DNA vector and a replication-deficient human adenovirus. We have demonstrated the induction of an FMDV-specific immune response and a neutralizing antibody response with the DNA vectors in mice, but preliminary potency and efficacy studies in swine are variable. However, the adenovirus vector induces a significant and long-lived neutralizing antibody response in mice and most importantly a neutralizing and protective response in swine. These results suggest that the empty capsid approach is a potential alternative to the current vaccination strategy.
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M., BLAKE. Reflections on the Foot-and-Mouth Disease Epidemic of 2001: an Irish Perspective. O.I.E (World Organisation for Animal Health), April 2021. http://dx.doi.org/10.20506/bull.2021.nf.3165.

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This year marks the 20-year anniversary of the foot-and-mouth disease (FMD) epidemic, which originated in the United Kingdom (UK) in February 2001, and subsequently spread to Ireland, the Netherlands and France.
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Kostova-Vassilevska, T. On The Use Of Models To Assess Foot-And-Mouth Disease Transmission And Control. Office of Scientific and Technical Information (OSTI), July 2004. http://dx.doi.org/10.2172/15014467.

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C., MIDDLEMISS. Reflections on the Foot-and-Mouth Disease Epidemic of 2001: a United Kingdom Perspective. O.I.E (World Organisation for Animal Health), April 2021. http://dx.doi.org/10.20506/bull.2021.nf.3166.

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Mwebe, Robert, Chester Kalinda, Ekwaro A. Obuku, Eve Namisango, Alison A. Kinengyere, Moses Ocan, Ann Nanteza, Savino Biryomumaisho, and Lawrence Mugisha. Epidemiology and effectiveness of interventions for Foot and Mouth Disease in Africa: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0039.

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Review question / Objective: What is the epidemiology and effectiveness of control measures for foot and mouth disease in African countries?’ PICOS: Description of elements Population/ problem/Setting: Artiodactyla (cloven ungulates), domestic (cattle, sheep, goats, and pigs), camels and wildlife (buffaloes, deer, antelope, wild pigs, elephant, giraffe, and camelids) affected by Foot and Mouth Disease (FMD) or Hoof and Mouth Disease (HMD) caused by the Foot and Mouth Disease Virus (FMDV) in Africa. Intervention: Prevention measures: vaccination, ‘biosafety and biosecurity’, sensitization of the public. Control measures: quarantine, movement control, closure of markets and stock routes, mouth swabbing of animals with infected materials (old technique that is no long applicable), culling, mass slaughter, stamping out and any other interventions or control measures generally accepted by the ‘community of practice’ of animal health practitioners. Comparator: areas that did not have any control activities for FMD, in head-to-head comparisons in the same study. Outcome: epidemiological outcomes: incidence, prevalence, patterns or trends, clinical symptoms, and risk factors. Effectiveness outcomes: success, and usefulness of the interventions measured as averted deaths, illness and infections, and costs associated with the interventions (cost–effectiveness). Study design: epidemiological designs include cohort design for incidence, cross sectional for prevalence and case-control for clinical symptoms and risk factors. Interventional designs include randomized controlled trials, cluster randomized trials, quasi-experimental designs – controlled before and after, interrupted time series, [regression discontinuity design, difference-in-difference, and propensity score matching]. Timelines: 1900 – 2022.
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