Relevant bibliographies by topics / Food metabolome / Dissertations / Theses
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Dissertations / Theses on the topic 'Food metabolome'

Author: Grafiati
Published: 11 March 2023

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1

Trimigno, Alessia <1989&gt. "A "Foodomic" Approach for the Evaluation of Food Quality and its Impact on the Human Metabolome." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amsdottorato.unibo.it/7917/1/Trimigno%20Alessia%20Tesi.pdf.

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In recent years, omic sciences have been increasingly employed in many research fields thanks to their high-throughput capabilities and holistic approach. Among the omics sciences, metabolomics and foodomics have recently emerged for the investigation of food and nutrition and their relation to the individual health and wellness status. The analytical platforms used are ideal for non-targeted analysis, due to their capability of detecting and identifying a large set of variables (or metabolites) in complex biological samples. The most employed metabolomics techniques are mass spectrometry an
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2

Ceci, Adriana Teresa. "Measuring the nutritional quality of local plant-based EUREGIO foods." Doctoral thesis, Università degli studi di Trento, 2022. https://hdl.handle.net/11572/355331.

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In the recent years, the consumer choices have been focused on health-promoting plant-based food and their preferences are oriented towards regional foodstuff from local productions. Therefore, an important factor for vegetables grown Trentino-Alto Adige (Italy) is to point out the added value of alpine farming to evaluate the nutritional values of farming products. Omics technologies (e.g. genomics, transcriptomics, proteomics and metabolomics) are aimed at investigating the assessment of different pools of molecules and how they are translated into the structure, function, and dynamics
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3

PIRAS, CRISTINA. "Metabolomic investigation of food matrices by ¹H NMR spectroscopy." Doctoral thesis, Università degli Studi di Cagliari, 2012. http://hdl.handle.net/11584/266182.

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The present Ph.D. work shows some applications on the NMR-based metabolomic approach in food science. The investigated food matrices are largely different, from a manufactured product that undergoes only physical treatments (bottarga), to a manufactured product where biochemical transformations take place (Fiore Sardo cheese), and, finally, a raw food (Argentina sphyraena). All of these food matrices were not chosen by chance, but they represent an important piece of economy of the island of Sardinia, or might be further valorized, gaining more importance in the near future. Indeed, bottarga a
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4

GHISONI, SILVIA. "UNTARGETED METABOLOMIC FINGERPRINTING FOR AUTHENTICITY AND TRACEABILITY OF FOODS." Doctoral thesis, Università Cattolica del Sacro Cuore, 2020. http://hdl.handle.net/10280/72714.

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La globalizzazione del mercato agroalimentare ha determinato una crescente attenzione da parte dei consumatori verso i prodotti alimentari, non solo in termini di qualità e di sicurezza, ma anche di origine geografica. Infatti, il territorio d’origine ha un forte impatto sull’alimento, dovuto alle condizioni pedoclimatiche che ne determinano le caratteristiche. Poiché non esistono dei metodi analitici di routine per l’autenticazione della provenienza geografica, lo scopo del progetto di ricerca è quello di determinare l’origine geografica e l’autenticità degli alimenti mediante profiling dei c
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GHISONI, SILVIA. "UNTARGETED METABOLOMIC FINGERPRINTING FOR AUTHENTICITY AND TRACEABILITY OF FOODS." Doctoral thesis, Università Cattolica del Sacro Cuore, 2020. http://hdl.handle.net/10280/72714.

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La globalizzazione del mercato agroalimentare ha determinato una crescente attenzione da parte dei consumatori verso i prodotti alimentari, non solo in termini di qualità e di sicurezza, ma anche di origine geografica. Infatti, il territorio d’origine ha un forte impatto sull’alimento, dovuto alle condizioni pedoclimatiche che ne determinano le caratteristiche. Poiché non esistono dei metodi analitici di routine per l’autenticazione della provenienza geografica, lo scopo del progetto di ricerca è quello di determinare l’origine geografica e l’autenticità degli alimenti mediante profiling dei c
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6

VIBERT, LAURENT. "Estimation des reserves en fer chez les coureurs de fond et de demi-fond." Nice, 1988. http://www.theses.fr/1988NICE6523.

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7

Hajjar, Ghina. "Authentication of food matrices using lipid markers obtained by isotopic and metabolomic NMR." Thesis, Nantes, 2019. http://www.theses.fr/2019NANT4083.

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Les indications relatives aux origines (géographique, botanique ou animale) des aliments constituent des critères de vente persuasifs surtout lorsque la provenance est reliée étroitement à la qualité du produit. Les risques de fraudes étant non négligeables, la mise en place de méthodes d’authentification robuste est alors une nécessité. La Résonance Magnétique Nucléaire (RMN) est l’une des techniques analytiques utilisées à cette fin. Elle permet d’identifier des marqueurs d’origines au sein de la matrice en question. A cet égard, les lipides peuvent être considérés comme source quasi-univers
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8

Fang, Zhou. "Effects of Carboxymethyl-Lysine in Heat Processed Foods on the Plasma Metabolome in Mice." DigitalCommons@USU, 2016. https://digitalcommons.usu.edu/etd/4752.

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The effect of dietary carboxymethyl-lysine (CML) on the metabolite profile of plasma was investigated. Mice were fed one of five diets including: AIN93 diet (negative control), a 45% kcal from fat Diet Induced Obesity diet (DIO; positive control); CML0, Total Western Diet (TWD) with low CML; CML1, TWD with medium CML, and CML2, TWD with high CML. In addition, plasma glucose across the five diet groups was also quantitatively measured in this study. According to the results, 93 compounds were detected in the mouse plasma samples using Gas Chromatography-Mass Spectrometry (GC-MS). Among all 93 d
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9

Cerff, Jeanne. "Optimisation of kefir biomass and metabolite production in conjunction with sensory evaluation." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/52979.

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Thesis (MSc)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: Developing countries such as South Africa are in dire need of nutritionally adequate dairy food and beverage sources that are ambient stable due to minimal access to refrigeration. One such product is Kefir, a naturally fermented milk beverage that originated in Caucasian China many centuries ago. The microorganisms responsible for fermentation of the milk are held together in a carbohydrate matrix in the form of small grains. These grains are then removed from the beverage prior to consumption, and added to fresh milk fo
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10

Kinkead, Ruth Ann. "Proteomic and metabolomic blood profiling to detect illegal drug use in food producing animals." Thesis, Queen's University Belfast, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706997.

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Despite the EU prohibition of anabolic substances administered to food producing animals, reports suggest that the use of growth promoting agents continues, pursued by improved animal health and subsequent financial gains. Current screening methods targeting known compounds are insufficient in discriminating endogenous levels from exogenous applications such as oestradiol. Problems also exist in the detection of corticosteroid misuse through long term, low dose dexamethasone and prednisolone administrations. Efforts have moved towards assessment of the biological response of animals to detect
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11

Uddin, Jalal. "NMR based Metabolomics in Food Chemistry." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3424379.

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Metabolomics is defined as the systematic analysis of hundreds or thousands of small metabolites present in a living system. It has emerge as an important field of study along with other, already established ‘omics’ sciences, i.e., genomics, proteomics and transcriptomics. Metabolomics is well established in the field of medicine, drug toxicity and disease diagnosis. Among the existing analytical techniques, NMR is a fast, reproducible and non-destructive technique to construct an informative snapshot of the metabolites under certain conditions. NMR data give metabolic signature information of
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12

Mori, Shinsuke. "Studies on the global screening of functional food ingredients in tomato using LC-MS and metabolomic analysis." Kyoto University, 2018. http://hdl.handle.net/2433/235095.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第21375号<br>農博第2299号<br>新制||農||1067(附属図書館)<br>学位論文||H30||N5148(農学部図書室)<br>京都大学大学院農学研究科食品生物科学専攻<br>(主査)教授 入江 一浩, 教授 橋本 渉, 准教授 後藤 剛<br>学位規則第4条第1項該当
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13

Martínez, Micaelo Nieves Beatriz. "Nutritional Immunotherapy: targeting immunometabolism with bioactive food compounds." Doctoral thesis, Universitat Rovira i Virgili, 2014. http://hdl.handle.net/10803/401827.

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La immunoteràpia nutricional es basa en fomentar la salut mitjançant el consum de compostos bioactius presents de manera natural en els aliments, com les procianidines, un tipus de flavonoid, i/o l’àcid docosahexaenoic (DHA), un àcid gras omega-3, optimitzant la funcionalitat del propi sistema immune i millorant així el seu paper com a responsable de la preservació de l’organisme enfront desestabilitzadors de la homeòstasis. La recerca que aquesta tesi abasta es centra en el paper del perfil nutricional en la regulació de la interacció immunitat-metabolisme (immunometabolisme). Amb aquesta fi
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14

Hu, Bizhen. "Metabolite Production in Callus Culture of Burdock (Arctium lappa L.)." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1357141954.

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15

Cheeseman, Kevin. "Aspects of Penicillium genomics : Molecular combing genome assembly, genetic exchange in food and potential for secondary metabolite production." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA112280/document.

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Les Penicilliums sont des champignons filamenteux appartenant au genre Ascomycota. Ces champignons ont été utilisés par l’homme pour la production de nourriture depuis des siècles. Plus récemment, ils ont aussi été utilisés dans l’industrie biotechnologique pour la production de composés chimiques d’intérêts pharmaceutiques. Certaines espèces de Penicillium sont par ailleurs des moisissures contaminants certains aliments, d’autres sont des pathogènes de plantes, y compris de certains fruits. Leur génomique est globalement peut connue. Dans cette étude, nous avons analysé les génomes de deux es
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16

Millet, Guillaume. "Facteurs mecaniques du cout energetique des locomotions terrestres, specificites du pas de patineur en ski de fond." Besançon, 1997. http://www.theses.fr/1997BESA3905.

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17

Duca, Radu Corneliu. "Food quality monitoring and analytical techniques optimization of some aliments within plant-animal correlation Contaminated aliments effects on the detoxication enzymes." Phd thesis, Université Paris Sud - Paris XI, 2009. http://tel.archives-ouvertes.fr/tel-00447178.

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Zéaralénone (Zen) est un métabolite secondaire de type polykétide biosynthétisé par différentes espèces de Fusarium (Fusarium graminearum, F. culmorum, F. equiseti, et F. crookwellense). Il s'agit d'un oestrogène non-stéroïdien (ou mycoestrogène) souvent nommé phytoestrogène. La Zen est un contaminant de cultures de céréales dans le monde entier (Bennett et Klich, 2003). Elle résiste à la plupart des traitements qui ont lieu au cours de la fabrication des denrées alimentaires. En dépit de sa structure non-stéroïdienes, le zen est capable de se lier aux récepteurs des oestrogènes et provoque de
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18

Frainay, Clément. "Système de recommandation basé sur les réseaux pour l'interprétation de résultats de métabolomique." Thesis, Toulouse 3, 2017. http://www.theses.fr/2017TOU30297/document.

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La métabolomique permet une étude à large échelle du profil métabolique d'un individu, représentatif de son état physiologique. La comparaison de ces profils conduit à l'identification de métabolites caractéristiques d'une condition donnée. La métabolomique présente un potentiel considérable pour le diagnostic, mais également pour la compréhension des mécanismes associés aux maladies et l'identification de cibles thérapeutiques. Cependant, ces dernières applications nécessitent d'inclure ces métabolites caractéristiques dans un contexte plus large, décrivant l'ensemble des connaissances relati
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19

Dinarès, Fernández Marta. "Evaluation of urban sustainability through the metabolic study of nutrient food flows: The case of the Grand Nador, Morocco, city-region." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399282.

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Por primera vez en la historia de la humanidad, una mayor proporción de la población global vive en áreas urbanas. En las próximas décadas, se espera que la mayor parte del crecimiento mundial previsto sea absorbido por las zonas urbanas costaneras del mundo en desarrollo, específicamente en las ciudades pequeñas y medianas así como en las zonas periféricas. En las últimas décadas, tanto las actividades humanas de producción y consumo de alimentos, cómo el fenómeno de la urbanización, se han identificado como actividades que contribuyen a alterar los ciclos naturales de los nutrientes del nit
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20

Figueiredo, Cardoso Tainã. "Analysis of the genetic basis of porcine meat quality and coat color by using genomic and transcriptomic tools." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/662617.

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Los principales objetivos de esta Tesis fueron investigar la base genética de la composición y deposito de la grasa en cerdos, e identificar los factores genéticos involucrados en el establecimiento de los patrones de pigmentación rubia vs roja en cerdos Mangalitza, mediante el uso de herramientas genómicas y transcriptómicas. En el primer estudio comparamos los patrones de expresión del músculo esquelético en dos grupos de cerdos Duroc, con diferentes perfiles de crecimiento y engrasamiento (HIGH: elevado espesor del tocino dorsal, grasa intramuscular, contenido de ácidos grasos saturados e i
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21

Coulmy, Nicolas. "Contribution à l'analyse cinématique et énergétique du pas de patineur en ski de fond : application à l'étude comparative de trois disciplines nordiques : le ski de fond, le biathlon et le combiné nordique : analyse comparative de systèmes d'analyse utilisant une modélisation filaire ou volumique et application à des études de cas en ski de fond." Université Joseph Fourier (Grenoble), 2000. http://www.theses.fr/2000GRE10137.

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L'analyse de la performance de haut niveau en ski de fond nécessite l'utilisation de méthodes non invasives telle que l'analyse du geste en 3D sans utilisation de marqueurs passifs ou actifs sur le skieur (approche écologique de l'analyse). Les objectifs de ce travail sont les suivants : - mise en évidence de comportements typiques propres à chacune des trois disciplines nordiques utilisant le pas de patineur : le ski de fond, le biathlon et le combiné nordique. Cette analyse, effectuée à partir de données enregistrées lors de compétitions de coupe du monde, permet de comparer les disciplines
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22

Leal, Witt María Jesús. "Efecto de una intervención del estilo de vida en el perfil metabólico de sujetos prepuberales con obesidad." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/457769.

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INTRODUCCIÓN: La obesidad en uno de los mayores factores de riesgo para desordenes metabólicos y cardiovasculares. El exceso de peso ganado durante la infancia aumenta el riesgo de enfermedad en el adulto, sin embargo revirtiendo esta condición tempranamente se reduce el riesgo futuro mejorando la calidad de vida de los individuos. OBJETIVOS: Una intervención en el estilo de vida de individuos prepuberales con obesidad podría provocar cambios en signaturas metabólicas en paralelo con mejoras del IMC. Nuestro objetivo principal fue determinar los efectos de una intervención en el estilo de vi
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23

Petrov, Dmitry. "The role of high-fat diet in an APP/PS1 model of familial Alzheimer disease = Efecto de una dieta rica en grasas en ratones APP/PS1, modelo familiar de la enfermedad de Alzheimer." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/359657.

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Global obesity is a pandemic status, estimated to affect over 2 billion people, and has resulted in an enormous strain on healthcare systems worldwide. The situation is compounded by the fact that apart from the direct costs associated with overweight pathology, obesity presents itself with a number of comorbidities, including an increased risk for the development of neurodegenerative disorders. Alzheimer disease (AD), the main cause of senile dementia, is no exception. Spectacular failure of the pharmaceutical industry to come up with effective AD treatment strategies is forcing scientific co
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24

Caballero, Solares Albert. "Optimització de l'ús de la proteïna en dietes per a orada (Sparus aurata)." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/295969.

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Si vol consolidar-se com a explotació econòmicament i ecològicament sostenible, la piscicultura ha de deslligar-se de la pesca mitjançant la reducció del contingut de farina de peix als pinsos. Aquesta fita pot ser assolida ajustant la proporció de proteïna de la dieta als requeriments nutricionals dels peixos, o bé emprant fonts de proteïna vegetal. Per a optimitzar l'ús de la proteïna en dietes per a orada (Sparus aurata) es varen usar tres suplements alimentaris: el glutamat, la glutamina i la taurina. En orades alimentades a base de farina de peix, el glutamat i la glutamina són més eficaç
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25

CIRCI, SIMONE. "Application of nuclear magnetic resonance spectroscopy in the study of complex matrices." Doctoral thesis, 2018. http://hdl.handle.net/11573/1209313.

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The aim of this PhD work was to apply the NMR based metabolomic approach to the study of complex matrices such as several food plants (pepper, celery, tomatoes, hemp, baobab, teas, blueberries and olive oils). A comprehensive description of the chemical composition in term of primary and secondary metabolites obtained by means of 1D and 2D experiments was reported and information regarding specific aspects (variety, type of production etc) were obtained. The study of stool samples of patients with liver cirrhosis was also carried out confirming the important contribution of the NMR approach in
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26

LA, BARBERA GIORGIA. "Mass spectrometry based metabolomics approaches for food safety, quality and nutrition." Doctoral thesis, 2017. http://hdl.handle.net/11573/1106474.

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In the last years, the research in food science and nutrition has grown parallel to the consumers’ concern about the quality and safety of the food they eat. As a result, ensuring food safety, food quality and investigating on nutrition has never been more necessary than today. More powerful analytical procedures are now required to detect and identify undesired and toxic compounds. Moreover, consumers demand is now moving toward the valorization of food with potential health benefits. The identification of bioactive compounds is crucial to provide customers a healthy diet. Finally, one of the
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27

(5930483), Xiaowei Zhang. "DIFFERENTIAL GUT MICROBIOTA AND FERMENTATION METABOLITE RESPONSE TO CORN BRAN ARABINOXYLANS IN DIFFERENT CHEMICAL AND PHYSICAL FORMS." Thesis, 2020.

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<div> <div> <div> <p>As a major part of the dietary fiber classification, plant polysaccharides often have chemically complex structures which may differ by genera and species, and perhaps even by genotype and growing environment. Arabinoxylans from cereal cell walls are known to differently impact human gut microbiota composition and fermentation metabolites due to variability in chemical structure, though specificities of structure to these functions are not known at the level of genotype ́ environment. In the first study, corn bran arabinoxylan (CAX) extracted from 4 genotypes ́ 3 growing
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28

Elliott, Sarah Beth. "Effects of pituitary pars intermedia dysfunction (PPID), season, and pasture diet on blood adrenocorticotropic hormone and metabolite concentrations in horses." 2010. http://trace.tennessee.edu/utk_gradthes/792.

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Studies described in this thesis were performed to investigate associations among season, diet, pituitary pars intermedia dysfunction (PPID) and blood concentrations of adrenocorticotropic hormone (ACTH), insulin, glucose, and leptin in horses. In the first study, higher ACTH concentrations were detected in horses affected with PPID. A seasonal increase in plasma ACTH concentration was detected in the late summer and early fall, but PPID did not affect the timing or duration of this increase. Pasture grazing raised glucose and insulin concentrations with a peak in September, at the same tim
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