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1

Massaro, Edward J., and John M. Rogers. Folate and Human Development. New Jersey: Humana Press, 2002. http://dx.doi.org/10.1385/1592591647.

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2

Preedy, Victor R., ed. B Vitamins and Folate. Cambridge: Royal Society of Chemistry, 2012. http://dx.doi.org/10.1039/9781849734714.

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3

J, Massaro Edward, and Rogers John M, eds. Folate and human development. Totowa, N.J: Humana Press, 2002.

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4

name, No. Folate and human development. Totowa, NJ: Humana Press, 2002.

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5

Bailey, Lynn B. Folate in health and disease. 2nd ed. Boca Raton: Taylor & Francis, 2010.

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6

1948-, Bailey Lynn B., ed. Folate in health and disease. New York: M. Dekker, 1995.

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7

McVitty, Rosalind Shirley. In vitro studies of folate catabolism. [S.l: The Author], 1997.

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8

Surdhar, Mohinderjeet Singh. Folate metabolism in the female weanling rat. Birmingham: Aston University. Department of Molecular Sciences, 1987.

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9

Kurtzweil, Paula. How folate can help prevent birth defects. [Rockville, MD: Dept. of Health and Human Services, Public Health Service, Food and Drug Administration, 1996.

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10

Kurtzweil, Paula. How folate can help prevent birth defects. [Rockville, MD: Dept. of Health and Human Services, Public Health Service, Food and Drug Administration, 1997.

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11

1963-, Gemmati Donato, and Transworld Research Network (Trivandrum, India), eds. Folate-pathway gene variants in Cancer: Haematological malignancies. Trivandrum: Transworld Research Network, 2008.

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12

B vitamins and folate: Chemistry, analysis, function and effects. Cambridge, U.K: Royal Society of Chemistry, 2012.

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13

D, Wright Jacqueline, and National Center for Health Statistics (U.S.), eds. Blood folate and vitamin B12: United States, 1988-95. Hyattsville, Md: U.S. Dept of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 1998.

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14

Kotsopoulos, Joanne. The effects of dietary folate on MNU-induced mammary tumourigenesis. Ottawa: National Library of Canada, 2002.

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15

Narasimhan, Kannan Laksmi. Neural tube defects: Role of folate, prevention strategies and genetics. Rijeka, Croatia: InTech, 2012.

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16

Kim, Tae Hee. Folate production in the large intestine of human infants and piglets. Ottawa: National Library of Canada, 2003.

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17

Stempak, Joanne Mary. The effects of folate deficiency on genomic and site-specific DNA methylation. Ottawa: National Library of Canada, 2003.

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18

Ward, Christopher Michael. Development of folate-targeted non-viral vectors for systemic cancer gene therapy. Birmingham: University of Birmingham, 2000.

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19

Aloba, Oladapo Babatunde. Nutritional status of B6 vitamers, vitamin B12 and folate in alcoholic patients. [Guildford]: University of Surrey, 1999.

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20

Song, Jacquelin. The effects of dietary folate on intestinal tumorigenesis in genetically predisposed murine models. Ottawa: National Library of Canada, 1999.

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21

Craig, Pamela. Prevention of neural tube defects: Compliance with D.O.H. recommendations for routine folate prophylaxis. [Londonderry]: WHSSB, 1996.

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22

O'Boyle, Maeve G. An investigation of iron folate and vitamin B12 status in non-institutionalised elderly in Northern Ireland. [S.l: The Author], 1995.

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23

Food and Agriculture Organization of the United Nations. and World Health Organization, eds. Requirements of vitamin A, iron, folate, and vitamin B12: Report of a joint FAO/WHO expert consultation. Rome: Food and Agriculture Organization of the United Nations, 1988.

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24

Institute of Medicine (U.S.). Standing Committee on the Scientific Evaluation of Dietary Reference Intakes., Institute of Medicine (U.S.). Panel on Folate, Other B Vitamins, and Choline., and Institute of Medicine (U.S.). Subcommittee on Upper Reference Levels of Nutrients., eds. DRI, dietary reference intakes for thiamin, riboflavin, niacin, vitamin B₆, folate, vitamin B₁₂, pantothenic acid, biotin, and choline. Washington, D.C: National Academy Press, 1998.

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25

Smirnakis, Francesca. The roel of folate and folylpoly-[gamma]-glutamate synthetase (FPGS) in the chemotherapeutics of human colon cancer cells. Ottawa: National Library of Canada, 2002.

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26

Cuskelly, Geraldine Josephine. Folate status and intervention studies in women o fchild-bearing age: Implications for the prevention of neural tube defects. [S.l: The Author], 1997.

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27

Fish, David Isherwood. Biochemical aspects and performance in the clinical laboratory of the assays used for the evaluation of vitaminB12 and Folate. Salford: University of Salford, 1986.

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28

Tighe, Paula. The influence of folate and related B-vitamins on plasma homocysteine in ischaemic heart disease patients and healthy controls. [S.l: The Author), 2004.

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29

Cooper, Bernard A., and Jacqueline A. Zittoun, eds. Folates and Cobalamins. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74364-1.

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30

The foliate head. Hornsea, East Yorkshire: Stanza Press, 2012.

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31

1938-, Zittoun J., and Cooper B. A. 1928-, eds. Folates and cobalamins. Berlin: Springer-Verlag, 1989.

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32

Rogers, John M., and Edward J. Massaro. Folate and Human Development. Humana Press, 2010.

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33

Rogers, John M., and Edward J. Massaro. Folate and Human Development. Humana Press, 2002.

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34

Rogers, John M., and Edward J. Massaro. Folate and Human Development. Humana Press, 2013.

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35

(Editor), Edward J. Massaro, and John M. Rogers (Editor), eds. Folate and Human Development. Humana Press, 2002.

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36

Bailey, Lynn B., ed. Folate in Health and Disease. CRC Press, 2009. http://dx.doi.org/10.1201/9781420071252.

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37

Folate in health and disease. 2nd ed. Boca Raton: Taylor & Francis, 2010.

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38

Folate in Health and Disease. 2nd ed. CRC, 2009.

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39

Bailey, Lynn B. Folate in Health and Disease. Taylor & Francis Group, 2009.

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40

Bailey, Lynn B. Folate in Health and Disease. Taylor & Francis Group, 2009.

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41

Folate and Disease Prevention 2006. Stationery Office, 2006.

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42

Bailey, Lynn B. Folate in Health and Disease. Taylor & Francis Group, 2009.

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43

Bailey, Lynn B. Folate in Health and Disease. Taylor & Francis Group, 1994.

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44

Bailey, Lynn B. Folate in Health and Disease. Taylor & Francis Group, 2009.

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45

Bailey, Lynn B. Folate in Health and Disease. Taylor & Francis Group, 1994.

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46

Fraser, Jamie L., Frédéric Sedel, and Charles P. Vendetti. Disorders of Cobalamin and Folate Metabolism. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0027.

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Cobalamin C deficiency (cblC) and related disorders of intracellular cobalamin metabolism may present at any time from the prenatal period through adolescence/adulthood and are due to deficiency of the cobalamin cofactors adenosylcobalamin and methylcobalamin. Chronic complications of cblC depend on the age at presentation and may include poor growth, renal dysfunction, neuropsychiatric manifestations, intellectual disability, strokes, progressive leukoencephalopathy and spinal cord degeneration, psychiatric manifestations and executive function deficits, and optic nerve and retinal anomalies. While less common than in isolated MMA, acute metabolic decompensation may occur in cblC patients due to accumulation of methylmalonic acid and associate metabolites and should be managed as in isolated MMA in conjunction with a metabolic consultant. The most common inborn error of folate (vitamin B9) metabolism relevant for adult patients is methylenetetrahydrofolate reductase (MTHFR) deficiency. Manifestations are primarily neurological, but the disorder may present in a substantial number of adults with psychiatric symptoms. Early recognition with adequate treatment is crucial.
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47

Gluckman, Sir Peter, Mark Hanson, Chong Yap Seng, and Anne Bardsley. Vitamin B9 (folate) in pregnancy and breastfeeding. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198722700.003.0012.

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Folate is a coenzyme in multiple biochemical pathways involving one-carbon metabolism, including amino acid metabolism, DNA and RNA synthesis, homocysteine metabolism, and methylation of DNA. The most overt consequence of folate deficiency is megaloblastic anaemia caused by the inhibition of DNA synthesis in red blood cell production. Folate deficiency may also influence the ability to maintain DNA methylation patterns in replicating cells, resulting in lasting phenotypic changes. Embryogenesis and fetal growth require higher levels of folate, which must be supplied maternally during pregnancy. A link between low maternal folate levels and the occurrence of neural tube defects has long been recognized. Other effects in pregnancy include increased risks of pre-eclampsia and placental vascular disorders. The general recommendation is for supplementation prior to conception and throughout pregnancy with 400 #amp;#x03BC;g of folic acid in tablet form, in addition to dietary sources, which can reduce the risk of neural tube defects.
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48

Bailey, Lynn B. Folate in Health and Disease, Second Edition. Taylor & Francis Group, 2010.

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49

Folate in Health and Disease, Second Edition. Taylor & Francis Group, 2017.

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50

Folate Story: A Vitamin under the Microscope. Troubador Publishing Limited, 2023.

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