Academic literature on the topic 'FILM'S CYTOTOXICITY'
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Journal articles on the topic "FILM'S CYTOTOXICITY"
Negrila, Catalin Constantin, Daniela Predoi, Rodica V. Ghita, Simona Liliana Iconaru, Steluta Carmen Ciobanu, Mirela Manea, Monica Luminita Badea, et al. "Multi-Level Evaluation of UV Action upon Vitamin D Enhanced, Silver Doped Hydroxyapatite Thin Films Deposited on Titanium Substrate." Coatings 11, no. 2 (January 21, 2021): 120. http://dx.doi.org/10.3390/coatings11020120.
Full textZemek, Josef, Petr Jiricek, Jana Houdkova, Martin Ledinsky, Miroslav Jelinek, and Tomas Kocourek. "On the Origin of Reduced Cytotoxicity of Germanium-Doped Diamond-Like Carbon: Role of Top Surface Composition and Bonding." Nanomaterials 11, no. 3 (February 25, 2021): 567. http://dx.doi.org/10.3390/nano11030567.
Full textXie, Rui Juan, Ming Zhong Li, Shen Zhou Lu, Wei Hua Sheng, and Yu Feng Xie. "Preparation of Sericin Film and its Cytocompatibility." Key Engineering Materials 342-343 (July 2007): 241–44. http://dx.doi.org/10.4028/www.scientific.net/kem.342-343.241.
Full textPuccetti, Matteo, Anna Donnadio, Maurizio Ricci, Loredana Latterini, Giulia Quaglia, Donatella Pietrella, Alessandro Di Michele, and Valeria Ambrogi. "Alginate Ag/AgCl Nanoparticles Composite Films for Wound Dressings with Antibiofilm and Antimicrobial Activities." Journal of Functional Biomaterials 14, no. 2 (February 1, 2023): 84. http://dx.doi.org/10.3390/jfb14020084.
Full textRakmae, Suriyan, and Nitinat Suppakarn. "Thermal Properties, Biodegradability and Cytotoxicity of PLA/Sericin Films." Advanced Materials Research 410 (November 2011): 86–89. http://dx.doi.org/10.4028/www.scientific.net/amr.410.86.
Full textPamlényi, Krisztián, Géza Regdon, Dániel Nemes, Ferenc Fenyvesi, Ildikó Bácskay, and Katalin Kristó. "Stability, Permeability and Cytotoxicity of Buccal Films in Allergy Treatment." Pharmaceutics 14, no. 8 (August 5, 2022): 1633. http://dx.doi.org/10.3390/pharmaceutics14081633.
Full textHissae Yassue-Cordeiro, Zandonai, Pereira Genesi, Santos Lopes, Sanchez-Lopez, Garcia, Camargo Fernandes-Machado, Severino, B. Souto, and Ferreira da Silva. "Development of Chitosan/Silver Sulfadiazine/Zeolite Composite Films for Wound Dressing." Pharmaceutics 11, no. 10 (October 14, 2019): 535. http://dx.doi.org/10.3390/pharmaceutics11100535.
Full textAlmeida, Nilsa Maria Galvão, Renata Lima, Thaís Francine Ribeiro Alves, Márcia de Araújo Rebelo, Patrícia Severino, and Marco Vinícius Chaud. "A novel dosage form for buccal administration of bupropion." Brazilian Journal of Pharmaceutical Sciences 51, no. 1 (March 2015): 91–100. http://dx.doi.org/10.1590/s1984-82502015000100010.
Full textSathya Seeli, David, Abinash Das, and Mani Prabaharan. "Zinc Oxide–Incorporated Chitosan–Poly(methacrylic Acid) Polyelectrolyte Complex as a Wound Healing Material." Journal of Functional Biomaterials 14, no. 4 (April 17, 2023): 228. http://dx.doi.org/10.3390/jfb14040228.
Full textConnor, Lydia M., Carol A. Ballinger, Thomas B. Albrecht, and Edward M. Postlethwait. "Interfacial phospholipids inhibit ozone-reactive absorption-mediated cytotoxicity in vitro." American Journal of Physiology-Lung Cellular and Molecular Physiology 286, no. 6 (June 2004): L1169—L1178. http://dx.doi.org/10.1152/ajplung.00397.2003.
Full textDissertations / Theses on the topic "FILM'S CYTOTOXICITY"
Cheung, Yeuk Kit. "Hemocompatible polymer thin films fabricated by Electrostatic Self-Assembly (ESA)." Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/31357.
Full textESA is a process to fabricate thin films bases on the electrostatic attraction between two oppositely charges. We used this technique to fabricate four PVP films and four PEI films. All films were exanimated by XPS and AFM. XPS data showed our coatings were successfully fabricated on substrates. AFM images revealed PVP coating was uniform, but PEI coatings had different morphologies due to diffusion and pH during the process.
Three preliminary hemocompatibility testes were performed to evaluate the hemocompatibility of the coatings. Platelet adhesion study showed the thin films inhibited platelet adhesion. All thin films were able to inhibit coagulation and were less cytotoxic. The studies suggested the ESA films were potentially hemocompatible.
Master of Science
Vieira, Fábio Bonorino. "DESENVOLVIMENTO DE FILMES DE ÓXIDOS NANOESTRUTURADOS EM LIGAS BINÁRIAS DE NIÓBIO-TITÂNIO." Centro Universitário Franciscano, 2015. http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/544.
Full textMade available in DSpace on 2018-08-16T20:28:58Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_FabioBonorinoVieira.pdf: 1042169 bytes, checksum: 9005bc8a7b7f41c4b1a750f6f427938e (MD5) Previous issue date: 2015-08-31
Due to their favorable properties as chemical stability, corrosion resistance, mechanical properties and biocompatibility, titanium and his alloys have been used for the manufacture of implants and prostheses for biomedical purposes. The stability of these metals and alloys is obtained due to a passivation layer of biocompatible titanium dioxide, naturally formed on the surface. In this work, titanium was anodized using potentiodynamic techniques forming a duplex with a film barrier back sheet type with a structure of type nanotubes on top. This film aims to metal passivation or alloy and enhance the characteristics of the material forward to interactions with the physiological environment. Although this oxide film is considered as a protective intermediate layer between the host tissue and the implant, it is considered the defense system a foreign body, and being very thin (only a few nanometers) and unstable under the action of body fluids. The current corrosion of metals and alloy with oxide coating in Ringer's solution increases towards Ti> Nb> Alloy 46.5% m / m Ti. The polished Nb shows high via cell viability and low genotoxicity. The anodized materials exhibit cytotoxicity and genotoxicity.
Devido suas propriedades favoráveis como estabilidade química, resistência à corrosão, propriedades mecânicas e biocompatibilidade, o titânio e suas ligas vem sendo utilizados para a fabricação de próteses e implantes para fins biomédicos. A estabilidade destes metais e ligas é obtida devido a uma camada de passivação biocompatível de dióxido de titânio, formada naturalmente sobre a superfície. Neste trabalho, o titânio foi anodizado utilizando técnicas potenciodinâmicas formando um filme do tipo duplex com uma camada inferior do tipo barreira com uma estrutura do tipo nanotubos na parte superior. Este filme tem como objetivo a passivação do metal ou da liga e potencializar as características dos materiais frente às interações com o meio fisiológico. Embora esse filme de óxido seja considerado como uma camada intermediária protetora entre os tecidos hospedeiros e o implante, ele é considerado pelo sistema imune, um corpo estranho, e sendo muito fino (apenas alguns nanômetros) e instável sob a ação dos fluidos corporais. A corrente de corrosão dos metais e da liga com o recobrimento de óxido em solução de Ringer aumenta no sentido Ti> Nb> liga 46,5 % m/m Ti. O Nb polido apresenta alta viabilidade celular e baixa genotoxidade. Os materiais anodizados apresentam citotoxidade e genotoxidade.
Filgueiras, Aline Luciano. "Adsorção de antibióticos em superfícies de nanopartículas de ouro ou prata e suas interações in vitro com filmes biológicos." Universidade Federal de Juiz de Fora (UFJF), 2017. https://repositorio.ufjf.br/jspui/handle/ufjf/5386.
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Nesta tese investigou-se as interações químicas dos antimicrobianos tinidazol, metronidazol, aztreonam, rifampicina e tetraciclina (TC) adsorvidos sobre superfícies metálicas de nanopartículas de ouro (AuNP) ou prata (AgNP) através das técnicas espectroscópicas de espalhamento Raman intensificado por superfície (SERS), de espalhamento Raman ressonante intensificado por superfície (SERRS) e de absorção no ultravioleta, visível e infravermelho próximo (UV-VIS-NIR). Também foram investigadas, a citotoxidade das AgNP, quitosana (QUIT), TC e das combinações AgNP com quitosana (AgNP+QUIT), e AgNP com QUIT e TC (AgNP+QUIT+TC) frente a células de fibroblastos bovinos. Foram obtidas as imagens de microscopia eletrônica de transmissão (TEM) das bactérias K.pneumoniae e S. aureus na ausência e presença das AgNP. Diferentes rotas sintéticas de AuNP e AgNP foram propostas, com o objetivo de se aprimorar as possíveis aplicações dessas sínteses. As AgNP devem ser pequenas para aplicações em experimentos biológicos e devem estar em ressonância com as radiações excitantes de comprimento de onda em 532, 633 ou 1064 nm quando forem utilizadas nos experimentos SERS. Os espectros SERS dos adsorbatos estudados foram obtidos na ausência e na presença dos modificadores de superfície 2-mercaptoetanol, polivinil álcool (PVA) ou íons cloreto. A presença destes modificadores superficiais permitiu monitorar os mecanismos de adsorção, que levaram a padrões espectrais SERS distintos. A análise dos espectros SERS da rifampicina foi baseada nas modificações observadas na estrutura eletrônica do grupo cromóforo, enquanto que para o tinidazol, metronidazol e aztreonam as diferenças nos padrões espectrais foram devidas a proximidade do sítio de adsorção do analito em relação à superfície metálica. A atribuição vibracional dos espectros Raman e SERS foi baseada em cálculos teóricos obtidos da teoria do funcional de densidade (DFT) das moléculas isoladas ou interagindo com átomos de metal. Este trabalho foi realizado em parceria com o Prof. Dr. Diego Paschoal da Universidade Federal do Rio de Janeiro e com o Prof. Dr. Hélio Ferreira dos Santos da Universidade Federal de Juiz de Fora. As imagens TEM das bactérias K. pneumoniae e S.aureus obtidas na ausência e presença das AgNP+QUIT foram realizadas em colaboração com o Dr. Celso Sant’Ana e o aluno Mateus Eugênio do Instituto Nacional de Metrologia, Qualidade e Tecnologia. Os ensaios de citotoxicidade das diferentes combinações de AgNP frente as células de fibroblastos bovinos foram realizados através do ensaio colorimétrico com brometo de 3, (-4,5-dimetiltiazol-2-il)-2,5-difeniltetrazolium (MTT). Este trabalho foi realizado em colaboração com a Profa. Dra. Michele Munk da Universidade Federal de Juiz de Fora.
In this thesis were investigated the chemical interaction of the antimicrobians tinidazole, metronidazole, aztreonam, rifampicin and tetracycline adsorbed on metallic surfaces of gold (AuNP) or silver nanoparticles (AgNP) by using the spectroscopic techniques surface enhanced Raman scattering (SERS), surface enhanced resonance Raman scattering (SERRS) and absorption in ultraviolet, visible and near infrared regions (UV-VIS-NIR). The cytotoxic effects of silver nanoparticles, chitosan (QUIT), tetracycline (TC) and its combinations AgNP with chitosan (AgNP+QUIT), and AgNP with QUIT and TC (AgNP+QUIT+TC) against bovine fibroblast cells were also investigated. The images using transmission electron microscopy (TEM) were obtained from the bacteria K.pneumoniae and S. aureus in the absence and presence of AgNP +QUIT. Different AuNP and AgNP were synthesized, with the aim of improving the possible applications of these syntheses. These have to be small in the biological experiments and should be in resonance with laser lines at 532, 633 or 1064 nm when used in the SERS experiments. The SERS spectra of the studied adsorbates were obtained in the absence and presence of the surfaces modifiers 2-mercaptoethanol, chloride ions or polyvinyl alcohol (PVA). The presence of these surfaces modifiers allowed monitoring adsorption mechanisms, which led to distinct SERS spectral patterns. The analyses of the SERS spectra of rifampicin were based on the observed changes in the electronic structure of the chromophore group, while for the tinidazole, metronidazole and aztreonam the differences in the spectral patterns were due to the proximity of anchor site of the analyte in relation to the metallic surface. The vibrational assignments of the Raman and SERS spectra were based on theoretical calculations obtained from density functional theory (DFT) of the isolated molecules or in interaction with metallic atoms. The DFT studies were made in collaboration with the Prof.Dr.Diego Paschoal from Universidade Federal do Rio de Janeiro and Prof.Dr Hélio Ferreira dos Santos from Universidade Federal de Juiz de Fora. The TEM images of K. pneumoniae and S.aureus bacteria obtained in the absence and in the presence of AgNP+QUIT were made in collaboration with the researcher Celso Sant’Ana and its student Mateus Eugênio from Instituto Nacional de Metrologia, Qualidade e Tecnologia. The cytotoxicity assays of the different combination of AgNP and chitosan and tetracycline against bovine fibroblast cells were made though colorimetric assay using MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide. The biological assay were made in collaboration with the Prof.Dr. Michele Munk and its students Leonara Fayer and Rafaella Zanetti from Universidade Federal de Juiz de Fora.
SINGH, TANVI. "POLYSACCHARIDE BASED FILM AS A FOOD PACKAGING MATERIAL." Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/20149.
Full textGonçalves, Victor Sérgio Fernandes. "Estudo das interações de filmes finos intermetálicos do tipo Ti- Me (Me = Ag, Au, Al, Cu) com sistemas biológicos, aplicados à funcionalização de elétrodos-sensores do tipo polimérico para dispositivos biomédicos." Master's thesis, 2018. http://hdl.handle.net/1822/55872.
Full textNas últimas décadas tem havido uma crescente solicitação na inovação e desenvolvimento de elétrodos/sensores biomédicos capazes de detetar sinais provenientes de tecidos vivos e convertê-los em sinais mensuráveis. Neste contexto tem havido uma grande quantidade de materiais a serem desenvolvidos e aplicados para o fabrico deste tipo de sensores. Dentro desses materiais, os materiais poliméricos funcionalizados com filmes finos intermetálicos de Ti-Me (Me=Al, Au, Ag e Cu) têm demonstrado um enorme potencial na obtenção de sensores com características muito especificas, tais como: boa elasticidade, manipulação fácil, baixo custo de produção e bom comportamento elétrico e mecânico. No entanto, têm surgido preocupações sobre o impacto que os nanomateriais e este novo conceito de sensor possam ter em sistemas biológicos, levando a questões sobre o tipo de repercussões podem ocorrer a longo prazo. Neste sentido, o trabalho efetuado durante esta dissertação teve como objetivo o estudo do impacto dos filmes finos de Ti-Me em fibroblastos e queratinócitos, procurando caracterizar a influência dos filmes no comportamento in vitro destas células. Na realização deste estudo foram produzidos filmes finos de Ti-Me por pulverização catódica em magnetrão não balanceado usando diferentes áreas de metal Me, sendo depois estudada a composição química dos filmes e o seu efeito sobre a viabilidade celular metabólica, indução de stress oxidativo, e capacidade inflamatória em fibroblastos e queratinócitos. Os resultados de composição química mostraram que houve a produção de filmes finos de Ti- Me com diferentes percentagens atómicas de Me e os estudos in vitro demonstram em alguns resultados um efeito tóxico principalmente dependente da percentagem atómica, mas também dependente do tempo de condicionamento e do Me. Apesar de terem sido observados alguns efeitos a nível da indução de stresse oxidativo e inflamação em alguns dos filmes de Ti-Me produzidos, é necessário realizar estudos in vitro mais detalhados e estudos in vivo de modo a ser possível retirar conclusões sobre a segurança da aplicação destes filmes na pele humana.
In recent decades there has been a growing demand for innovation and development of biomedical electrodes/sensors capable of detecting signals from living tissue and convert them into measurable signals. In this context, a great number of materials have been developed and applied for the manufacture of this type of sensors. Within these materials the polymeric materials functionalized with intermetallic thin films of Ti-Me (Me = Al, Au, Ag and Cu) have demonstrated a great potential to obtain sensors with very specific characteristics, such as: good elasticity, easy handling, low production cost and good electrical and mechanical behavior. However, concerns have arisen about the impact that nanomaterials and this new sensor concept may have on biological systems, leading to questions about the type of cellular interactions that can be triggered and the kind of long-term efects that may occur. Given that Ti-Me thin film sensors are designed to interact with the surface of the human skin, it is important to study the cytotoxic effects that they may have when applied to cells that are characteristic of this organ. In this sense, the objective of this work was to study the impact of Ti-Me thin films on the in vitro biological behavior of fibroblasts and keratinocytes. In this study, thin films of Ti-Me were produced by unbalanced magnetron sputtering using different areas of Me metal. The chemical composition of the films and their effect on metabolic cell viability, induction of oxidative stress, and inflammatory capacity in fibroblasts and keratinocytes was evaluated. The results of chemical composition showed that Ti-Me thin films were produced with different atomic percentages of Me. The in vitro studies demonstrated some cytotoxic effect, capacity to induce oxidative stress and inflammation, dependent on the atomic percentage, time of incubation and the nature of Me atom. Although potential cytotoxic effects have been observed in some of the produced Ti-Me films, more studies have to be performed in order to draw conclusions about the safety of the application of these films on human skin.
Morgado, João Frederico Lourenço dos Santos Barata. "Preparation of biopolymer-drug formulations for cancer drug delivery." Master's thesis, 2018. http://hdl.handle.net/10362/69932.
Full textBook chapters on the topic "FILM'S CYTOTOXICITY"
Ozeki, K., Hideyuki Aoki, and Y. Fukui. "Crystallization of Sputtered Hydroxyapatite Films by Hydrothermal Technique and Its Cytotoxicity." In Bioceramics 17, 195–98. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-961-x.195.
Full textSabel-Grau, Tina, Arina Tyushina, Rahima Rahman, Cigdem Babalik, Zhenfang Zhang, and Marga C. Lensen. "Volume Holographic Structuring of Special Hydrogel Films by Photochemical Crosslinking." In Holography - Recent Advances and Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108265.
Full textRadotić, Ksenija, Dragica Spasojević, and Danica Zmejkoski. "Lignin-based Materials for Biomedical Applications: Basic Requirements and Properties." In Lignin-based Materials, 85–105. The Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781839167843-00085.
Full textConference papers on the topic "FILM'S CYTOTOXICITY"
Mensah-Darkwa, Kwadwo, Ram K. Gupta, and Dhananjay Kumar. "Fabrication and Characterization of Hydroxyapatite-Magnesium Composite Thin Films on Magnesium Plates for Implant Applications." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-86918.
Full textZhao, Lingyun, Xiaoyu Xu, Xiaowen Wang, Xiaodong Zhang, Fuping Gao, and Jintian Tang. "Fabrication, characterization and in-vitro cytotoxicity of magnetic nanocomposite polymeric film for multi-functional medical application." In Second International Conference on Smart Materials and Nanotechnology in Engineering, edited by Jinsong Leng, Anand K. Asundi, and Wolfgang Ecke. SPIE, 2009. http://dx.doi.org/10.1117/12.841207.
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