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Journal articles on the topic 'Fibrous matrices'

Author: Grafiati

Published: 6 September 2023

Last updated: 7 September 2023

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1

Hall, Matthew S., Farid Alisafaei, Ehsan Ban, Xinzeng Feng, Chung-Yuen Hui, Vivek B. Shenoy, and Mingming Wu. "Fibrous nonlinear elasticity enables positive mechanical feedback between cells and ECMs." Proceedings of the National Academy of Sciences 113, no. 49 (November 21, 2016): 14043–48. http://dx.doi.org/10.1073/pnas.1613058113.

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In native states, animal cells of many types are supported by a fibrous network that forms the main structural component of the ECM. Mechanical interactions between cells and the 3D ECM critically regulate cell function, including growth and migration. However, the physical mechanism that governs the cell interaction with fibrous 3D ECM is still not known. In this article, we present single-cell traction force measurements using breast tumor cells embedded within 3D collagen matrices. We recreate the breast tumor mechanical environment by controlling the microstructure and density of type I collagen matrices. Our results reveal a positive mechanical feedback loop: cells pulling on collagen locally align and stiffen the matrix, and stiffer matrices, in return, promote greater cell force generation and a stiffer cell body. Furthermore, cell force transmission distance increases with the degree of strain-induced fiber alignment and stiffening of the collagen matrices. These findings highlight the importance of the nonlinear elasticity of fibrous matrices in regulating cell–ECM interactions within a 3D context, and the cell force regulation principle that we uncover may contribute to the rapid mechanical tissue stiffening occurring in many diseases, including cancer and fibrosis.

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2

Fanti, Lisa A., and Eduardo D. Glandt. "Partitioning of spherical particles into fibrous matrices." Journal of Colloid and Interface Science 135, no. 2 (March 1990): 385–95. http://dx.doi.org/10.1016/0021-9797(90)90008-c.

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3

Fanti, Lisa A., and Eduardo D. Glandt. "Partitioning of spherical particles into fibrous matrices." Journal of Colloid and Interface Science 135, no. 2 (March 1990): 396–404. http://dx.doi.org/10.1016/0021-9797(90)90009-d.

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4

Levick, J. R. "FLOW THROUGH INTERSTITIUM AND OTHER FIBROUS MATRICES." Quarterly Journal of Experimental Physiology 72, no. 4 (October 10, 1987): 409–37. http://dx.doi.org/10.1113/expphysiol.1987.sp003085.

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5

Yang, Xingxing, Linpeng Fan, Linlin Ma, Yunyi Wang, Si Lin, Fan Yu, Xiaohan Pan, Gejie Luo, Dongdong Zhang, and Hongsheng Wang. "Green electrospun Manuka honey/silk fibroin fibrous matrices as potential wound dressing." Materials & Design 119 (April 2017): 76–84. http://dx.doi.org/10.1016/j.matdes.2017.01.023.

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6

Irzhak, V. I. "Strengthening of Fibrous Composites with Nanoparticles." Russian Journal of Physical Chemistry A 95, no. 9 (September 2021): 1757–63. http://dx.doi.org/10.1134/s0036024421090065.

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Abstract Ways and mechanisms of strengthening polymer fiber composites by modifying matrices with nanoparticles and grafting the latter onto fibers are considered: chemical vapor deposition, electrophoretic and chemical interaction.

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7

Jamal Shannag, M., and Tareq Bin Ziyyad. "Flexural response of ferrocement with fibrous cementitious matrices." Construction and Building Materials 21, no. 6 (June 2007): 1198–205. http://dx.doi.org/10.1016/j.conbuildmat.2006.06.021.

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8

Chuang, Yu-Chun, Limin Bao, Mei-Chen Lin, Ching-Wen Lou, and TingAn Lin. "Mechanical and Static Stab Resistant Properties of Hybrid-Fabric Fibrous Planks: Manufacturing Process of Nonwoven Fabrics Made of Recycled Fibers." Polymers 11, no. 7 (July 3, 2019): 1140. http://dx.doi.org/10.3390/polym11071140.

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With the development of technology, fibers and textiles are no longer exclusive for the use of clothing and decoration. Protective products made of high-strength and high-modulus fibers have been commonly used in different fields. When exceeding the service life, the protective products also need to be replaced. This study proposes a highly efficient recycling and manufacturing design to create more added values for the waste materials. With a premise of minimized damage to fibers, the recycled selvage made of high strength PET fibers are reclaimed to yield high performance staple fibers at a low production cost. A large amount of recycled fibers are made into matrices with an attempt to decrease the consumption of new materials, while the combination of diverse plain woven fabrics reinforces hybrid-fabric fibrous planks. First, with the aid of machines, recycled high strength PET fibers are processed into staple fibers. Using a nonwoven process, low melting point polyester (LMPET) fibers and PET staple fibers are made into PET matrices. Next, the matrices and different woven fabrics are combined in order to form hybrid-fabric fibrous planks. The test results indicate that both of the PET matrices and fibrous planks have good mechanical properties. In particular, the fibrous planks yield diverse stab resistances from nonwoven and woven fabrics, and thus have greater stab performance.

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9

Zhang, Juntao, Yang Sun, Yan Zhao, Benmei Wei, Chengzhi Xu, Lang He, Cristiano L. P. Oliveira, and Haibo Wang. "Centrifugation-induced fibrous orientation in fish-sourced collagen matrices." Soft Matter 13, no. 48 (2017): 9220–28. http://dx.doi.org/10.1039/c7sm01871a.

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10

Rizvi, Mohd Suhail, Anupam Pal, and Sovan Lal Das. "Structure-induced nonlinear viscoelasticity of non-woven fibrous matrices." Biomechanics and Modeling in Mechanobiology 15, no. 6 (April 18, 2016): 1641–54. http://dx.doi.org/10.1007/s10237-016-0788-z.

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11

Mu, Bingnan, Wei Li, Helan Xu, Lan Xu, and Yiqi Yang. "Freeze-extrusion for controllable assembly of 3-dimensional ultra-fine and amorphous fibrous matrices: potential applications in sorption." Journal of Materials Chemistry A 6, no. 22 (2018): 10320–30. http://dx.doi.org/10.1039/c8ta01845f.

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12

Curtis, P. T. "The fatigue behaviour of fibrous composite materials." Journal of Strain Analysis for Engineering Design 24, no. 4 (October 1, 1989): 235–44. http://dx.doi.org/10.1243/03093247v244235.

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The fatigue behaviour of high performance continuous fibre reinforced composite materials based on organic matrices has been reviewed. Methods of performing fatigue tests are discussed. Fatigue damage development processes are reviewed for typical unidirectional and laminated materials and fatigue performance compared for different materials. The effects of stress concentrators and environmental exposure are considered and the use of alternative forms of composite such as woven materials discussed. A comparison with the fatigue of metals is made.

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13

Matera, Daniel L., Katarina M. DiLillo, Makenzee R. Smith, Christopher D. Davidson, Ritika Parikh, Mohammed Said, Carole A. Wilke, et al. "Microengineered 3D pulmonary interstitial mimetics highlight a critical role for matrix degradation in myofibroblast differentiation." Science Advances 6, no. 37 (September 2020): eabb5069. http://dx.doi.org/10.1126/sciadv.abb5069.

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Fibrosis, characterized by aberrant tissue scarring from activated myofibroblasts, is often untreatable. Although the extracellular matrix becomes increasingly stiff and fibrous during disease progression, how these physical cues affect myofibroblast differentiation in 3D is poorly understood. Here, we describe a multicomponent hydrogel that recapitulates the 3D fibrous structure of interstitial tissue regions where idiopathic pulmonary fibrosis (IPF) initiates. In contrast to findings on 2D hydrogels, myofibroblast differentiation in 3D was inversely correlated with hydrogel stiffness but positively correlated with matrix fibers. Using a multistep bioinformatics analysis of IPF patient transcriptomes and in vitro pharmacologic screening, we identify matrix metalloproteinase activity to be essential for 3D but not 2D myofibroblast differentiation. Given our observation that compliant degradable 3D matrices amply support fibrogenesis, these studies demonstrate a departure from the established relationship between stiffness and myofibroblast differentiation in 2D, and provide a new 3D model for studying fibrosis and identifying antifibrotic therapeutics.

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14

Zonca, Michael R., Philip S. Yune, James K. Williams, Minghao Gu, Andrea M. Unser, Joseph Imbrogno, Georges Belfort, and Yubing Xie. "Enhanced Stem Cell Pluripotency in Surface-Modified Electrospun Fibrous Matrices." Macromolecular Bioscience 14, no. 2 (September 16, 2013): 215–24. http://dx.doi.org/10.1002/mabi.201300252.

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15

Liakos, I., L. Rizzello, H. Hajiali, V. Brunetti, R. Carzino, P. P. Pompa, A. Athanassiou, and E. Mele. "Fibrous wound dressings encapsulating essential oils as natural antimicrobial agents." Journal of Materials Chemistry B 3, no. 8 (2015): 1583–89. http://dx.doi.org/10.1039/c4tb01974a.

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Essential oils with high antibiotic activity were incorporated into cellulose acetate natural polymer. By using the electrospinning technique, nanofibrous matrices were prepared to be used as effective antimicrobial wound dressings.

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16

DePalma, Samuel J., Christopher D. Davidson, Austin E. Stis, Adam S. Helms, and Brendon M. Baker. "Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices." Biomaterials Science 9, no. 1 (2021): 93–107. http://dx.doi.org/10.1039/d0bm01247e.

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17

Zhabin, A. N., D. V. Sidorov, and A. N. Nyafkin. "FIBROUS COMPOSITE MATERIALS WITH A METAL MATRIX (review)." Proceedings of VIAM, no. 6 (2021): 27–35. http://dx.doi.org/10.18577/2307-6046-2021-0-6-27-35.

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The article provides an overview of the literature in the field of composite materials (CM) based on metal matrices reinforced with carbon fibers. The main structural, physical and mechanical properties and morphology of such CMS are briefly described. The structure and properties of new CMS from multilayer metal-intermetallic multilayer laminates reinforced with carbon and ceramic fibers are also presented. Application of the method of ultrasonic consolidation for the manufacture of multilayer fibrous CMs based on metal-intermetallic laminates provides high adhesion of fibers with an intermetallic layer.

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18

Song, Dawei, Nicholas Hugenberg, and Assad A Oberai. "Recovery of 3D Tractions Exerted by Cells on Fibrous Extracellular Matrices." Molecular & Cellular Biomechanics 16, S2 (2019): 45. http://dx.doi.org/10.32604/mcb.2019.07138.

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19

Samanta, Archana, Sonam Takkar, Ritu Kulshreshtha, Bhanu Nandan, and Rajiv K. Srivastava. "Nano-silver stabilized Pickering emulsions and their antimicrobial electrospun fibrous matrices." Biomedical Physics & Engineering Express 3, no. 3 (May 11, 2017): 035011. http://dx.doi.org/10.1088/2057-1976/aa6c32.

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20

Cao, G., Y. Li, Y. Qi, Y. Qiao, J. He, H. Zhang, W. Cui, and M. Zhou. "NIR-responsible and optically monitored nanoparticles release from electrospinning fibrous matrices." Materials Today Advances 6 (June 2020): 100044. http://dx.doi.org/10.1016/j.mtadv.2019.100044.

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21

Cottenden, David J., and Michelle L. Oyen. "Quantitative modelling of viscoelasticity of isotropic fibrous composites with viscoelastic matrices." Theoretical and Applied Mechanics Letters 1, no. 5 (2011): 052006. http://dx.doi.org/10.1063/2.1105206.

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22

Davidson, Christopher D., Danica Kristen P. Jayco, Daniel L. Matera, Samuel J. DePalma, Harrison L. Hiraki, William Y. Wang, and Brendon M. Baker. "Myofibroblast activation in synthetic fibrous matrices composed of dextran vinyl sulfone." Acta Biomaterialia 105 (March 2020): 78–86. http://dx.doi.org/10.1016/j.actbio.2020.01.009.

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23

Ventre, Maurizio, Valerio Coppola, Carlo F. Natale, and Paolo A. Netti. "Aligned fibrous decellularized cell derived matrices for mesenchymal stem cell amplification." Journal of Biomedical Materials Research Part A 107, no. 11 (July 30, 2019): 2536–46. http://dx.doi.org/10.1002/jbm.a.36759.

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24

Yuan, Yue, Jialong Shen, and Sonja Salmon. "Developing Enzyme Immobilization with Fibrous Membranes: Longevity and Characterization Considerations." Membranes 13, no. 5 (May 20, 2023): 532. http://dx.doi.org/10.3390/membranes13050532.

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Fibrous membranes offer broad opportunities to deploy immobilized enzymes in new reactor and application designs, including multiphase continuous flow-through reactions. Enzyme immobilization is a technology strategy that simplifies the separation of otherwise soluble catalytic proteins from liquid reaction media and imparts stabilization and performance enhancement. Flexible immobilization matrices made from fibers have versatile physical attributes, such as high surface area, light weight, and controllable porosity, which give them membrane-like characteristics, while simultaneously providing good mechanical properties for creating functional filters, sensors, scaffolds, and other interface-active biocatalytic materials. This review examines immobilization strategies for enzymes on fibrous membrane-like polymeric supports involving all three fundamental mechanisms of post-immobilization, incorporation, and coating. Post-immobilization offers an infinite selection of matrix materials, but may encounter loading and durability issues, while incorporation offers longevity but has more limited material options and may present mass transfer obstacles. Coating techniques on fibrous materials at different geometric scales are a growing trend in making membranes that integrate biocatalytic functionality with versatile physical supports. Biocatalytic performance parameters and characterization techniques for immobilized enzymes are described, including several emerging techniques of special relevance for fibrous immobilized enzymes. Diverse application examples from the literature, focusing on fibrous matrices, are summarized, and biocatalyst longevity is emphasized as a critical performance parameter that needs increased attention to advance concepts from lab scale to broader utilization. This consolidation of fabrication, performance measurement, and characterization techniques, with guiding examples highlighted, is intended to inspire future innovations in enzyme immobilization with fibrous membranes and expand their uses in novel reactors and processes.

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25

Solarz, Daria, Tomasz Witko, Robert Karcz, Ivana Malagurski, Marijana Ponjavic, Steva Levic, Aleksandra Nesic, Maciej Guzik, Sanja Savic, and Jasmina Nikodinovic-Runic. "Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/P(3HO) scaffolds for tissue engineering applications." RSC Advances 13, no. 34 (2023): 24112–28. http://dx.doi.org/10.1039/d3ra03021k.

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The work investigates fabrication and physicochemical and biological evaluation of electrospun polyhydroxyoctanoate and polylactic acid blend fibers. The results suggest that the obtained fibrous matrices can be used as biomimetic biomaterials.

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26

Mu, Bingnan, Wei Li, Helan Xu, Lan Xu, and Yiqi Yang. "Correction: Freeze-extrusion for controllable assembly of 3-dimensional ultra-fine and amorphous fibrous matrices: potential applications in sorption." Journal of Materials Chemistry A 6, no. 33 (2018): 16273. http://dx.doi.org/10.1039/c8ta90182a.

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Correction for ‘Freeze-extrusion for controllable assembly of 3-dimensional ultra-fine and amorphous fibrous matrices: potential applications in sorption’ by Bingnan Mu et al., J. Mater. Chem. A, 2018, 6, 10320–10330.

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27

Herbanu, Aldi, Ika Dewi Ana, Retno Ardhani, and Widowati Siswomihardjo. "Fibrous PVA Matrix Containing Strontium-Substituted Hydroxyapatite Nanoparticles from Golden Apple Snail (Pomacea canaliculata L.) Shells for Bone Tissue Engineering." Bioengineering 10, no. 7 (July 17, 2023): 844. http://dx.doi.org/10.3390/bioengineering10070844.

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A scaffold that replicates the physicochemical composition of bone at the nanoscale level is a promising replacement for conventional bone grafts such as autograft, allograft, or xenograft. However, its creation is still a major challenge in bone tissue engineering. The fabrication of a fibrous PVA-HA/Sr matrix made of strontium (Sr)-substituted hydroxyapatite from the shell of Pomecea canaliculate L. (golden apple snail) is reported in this work. Since the fabrication of HAp from biogenic resources such as the shell of golden apple snail (GASs) should be conducted at very high temperature and results in high crystalline HAp, Sr substitution to Ca was applied to reduce crystallinity during HAp synthesis. The resulted HAp and HA/Sr nanoparticles were then combined with PVA to create fibrous PVA-HAp or PVA-HA/Sr matrices in 2 or 4 mol % Sr ions substitution by electrospinning. The nanofiber diameter increased gradually by the addition of HAp, HA/Sr 2 mol %, and HA/Sr 4 mol %, respectively, into PVA. The percentage of the swelling ratio increased and reached the maximum value in PVA-HA/Sr-4 mol %, as well as in its protein adsorption. Furthermore, the matrices with HAp or HA/Sr incorporation exhibited good bioactivity, increased cell viability and proliferation. Therefore, the fibrous matrices generated in this study are considered potential candidates for bone tissue engineering scaffolds. Further in vivo studies become an urgency to valorize these results into real clinical application.

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28

Heo, Su-Jin, Kwang Hoon Song, Shreyasi Thakur, Liane M. Miller, Xuan Cao, Ana P. Peredo, Breanna N. Seiber, et al. "Nuclear softening expedites interstitial cell migration in fibrous networks and dense connective tissues." Science Advances 6, no. 25 (June 2020): eaax5083. http://dx.doi.org/10.1126/sciadv.aax5083.

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Dense matrices impede interstitial cell migration and subsequent repair. We hypothesized that nuclear stiffness is a limiting factor in migration and posited that repair could be expedited by transiently decreasing nuclear stiffness. To test this, we interrogated the interstitial migratory capacity of adult meniscal cells through dense fibrous networks and adult tissue before and after nuclear softening via the application of a histone deacetylase inhibitor, Trichostatin A (TSA) or knockdown of the filamentous nuclear protein Lamin A/C. Our results show that transient softening of the nucleus improves migration through microporous membranes, electrospun fibrous matrices, and tissue sections and that nuclear properties and cell function recover after treatment. We also showed that biomaterial delivery of TSA promoted in vivo cellularization of scaffolds by endogenous cells. By addressing the inherent limitations to repair imposed by nuclear stiffness, this work defines a new strategy to promote the repair of damaged dense connective tissues.

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29

CHEN, Hou Y., Jian-Min SUN, Michael J. HENDZEL, Jerome B. RATTNER, and James R. DAVIE. "Changes in the nuclear matrix of chicken erythrocytes that accompany maturation." Biochemical Journal 320, no. 1 (November 15, 1996): 257–65. http://dx.doi.org/10.1042/bj3200257.

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The protein composition and structure of nuclear matrices isolated from adult chicken immature and mature erythrocytes were analysed. Visualization of nuclear matrices by electron microscopy showed that immature-erythrocyte nuclear matrices had internal structures, while most mature-erythrocyte nuclear matrices did not. Both mature- and immature-erythrocyte nuclear matrices were surrounded by a fibrous network of intermediate filaments. Two-dimensional gel electrophoretic analysis of proteins obtained from fractionated nuclear matrices led to the assignment of the proteins as components of the nuclear pore-lamina, internal matrix, or cytoskeleton. Common and different proteins belonging to one of the three groups were identified in nuclear matrices of immature and mature erythrocytes. Investigation of the partitioning of histone deacetylase activity, an enzyme associated with the internal matrix, among the erythroid nuclear matrix fractions provided evidence that mature- and immature-erythrocyte nuclear matrices have internal structures. However, the activity of histone deacetylase and level of internal matrix proteins from mature-erythrocyte nuclear matrices were less than those from immature-erythrocyte matrices. The low levels of nuclear RNA and internal matrix proteins may account for lack of visual evidence for an internal matrix in mature erythrocytes.

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30

Cao, Xuan, Ehsan Ban, Brendon M. Baker, Yuan Lin, Jason A. Burdick, Christopher S. Chen, and Vivek B. Shenoy. "Multiscale model predicts increasing focal adhesion size with decreasing stiffness in fibrous matrices." Proceedings of the National Academy of Sciences 114, no. 23 (May 3, 2017): E4549—E4555. http://dx.doi.org/10.1073/pnas.1620486114.

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We describe a multiscale model that incorporates force-dependent mechanical plasticity induced by interfiber cross-link breakage and stiffness-dependent cellular contractility to predict focal adhesion (FA) growth and mechanosensing in fibrous extracellular matrices (ECMs). The model predicts that FA size depends on both the stiffness of ECM and the density of ligands available to form adhesions. Although these two quantities are independent in commonly used hydrogels, contractile cells break cross-links in soft fibrous matrices leading to recruitment of fibers, which increases the ligand density in the vicinity of cells. Consequently, although the size of focal adhesions increases with ECM stiffness in nonfibrous and elastic hydrogels, plasticity of fibrous networks leads to a departure from the well-described positive correlation between stiffness and FA size. We predict a phase diagram that describes nonmonotonic behavior of FA in the space spanned by ECM stiffness and recruitment index, which describes the ability of cells to break cross-links and recruit fibers. The predicted decrease in FA size with increasing ECM stiffness is in excellent agreement with recent observations of cell spreading on electrospun fiber networks with tunable cross-link strengths and mechanics. Our model provides a framework to analyze cell mechanosensing in nonlinear and inelastic ECMs.

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31

Volfkovich, Yurii M., Nataliya A. Kononenko, Alexey A. Mikhalin, Мarina M. Kardash, Alexey Yu Rychagov, Sergei V. Tsipliaev, Svetlana A. Shkirskaya, and Valentin E. Sosenkin. "Capacitive deionization of water involving mosaic membranes based on fibrous polymer matrices." DESALINATION AND WATER TREATMENT 181 (2020): 77–87. http://dx.doi.org/10.5004/dwt.2020.25410.

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32

Takahashi, Atsushi, Mats Häggkvist, and Tie-Qiang Li. "Capillary penetration in fibrous matrices studied by dynamic spiral magnetic resonance imaging." Physical Review E 56, no. 2 (August 1, 1997): 2035–42. http://dx.doi.org/10.1103/physreve.56.2035.

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33

Wu, Shuting, Zeeshan Ahmad, Jing-Song Li, and Ming-Wei Chang. "Controlled engineering of highly aligned fibrous dosage form matrices for controlled release." Materials Letters 232 (December 2018): 134–37. http://dx.doi.org/10.1016/j.matlet.2018.08.101.

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34

Gurave, Pramod M., Shweta Singh, Anilkumar Yadav, Bhanu Nandan, and Rajiv K. Srivastava. "Electrospinning of a Near Gel Resin To Produce Cross-Linked Fibrous Matrices." Langmuir 36, no. 9 (February 13, 2020): 2419–26. http://dx.doi.org/10.1021/acs.langmuir.9b03870.

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35

Giraud-Guille, Marie-Madeleine. "Direct visualization of microtomy artefacts in sections of twisted fibrous extracellular matrices." Tissue and Cell 18, no. 4 (January 1986): 603–20. http://dx.doi.org/10.1016/0040-8166(86)90024-8.

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36

Cooper, Ashleigh, Matthew Leung, and Miqin Zhang. "Polymeric Fibrous Matrices for Substrate-Mediated Human Embryonic Stem Cell Lineage Differentiation." Macromolecular Bioscience 12, no. 7 (May 30, 2012): 882–92. http://dx.doi.org/10.1002/mabi.201100269.

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37

Goodenough, U. W., and J. E. Heuser. "The Chlamydomonas cell wall and its constituent glycoproteins analyzed by the quick-freeze, deep-etch technique." Journal of Cell Biology 101, no. 4 (October 1, 1985): 1550–68. http://dx.doi.org/10.1083/jcb.101.4.1550.

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Using the quick-freeze, deep-etch technique, we have analyzed the structure of the intact cell wall of Chlamydomonas reinhardi, and have visualized its component glycoproteins after mechanical shearing and after depolymerization induced by perchlorate or by the wall-disrupting agent, autolysin. The intact wall has previously been shown in a thin-section study (Roberts, K., M. Gurney-Smith, and G. J. Hills, 1972, J. Ultrastruct. Res. 40:599-613) to consist of a discrete central triplet bisecting a meshwork of fibrils. The deep-etch technique provides additional information about the architecture of each of these layers under several different experimental conditions, and demonstrates that each layer is constructed from a distinct set of components. The innermost layer of the central triplet proves to be a fibrous network which is stable to perchlorate but destabilized by autolysin, disassembling into fibrillar units we designate as "fishbones." The medial layer of the triplet is a loose assemblage of large granules. The outer layer is a thin, crystalline assembly that is relatively unaffected by autolysin. It depolymerizes into two glycoprotein species, one fibrous and one globular. The wall glycoproteins prove to be structurally similar to two fibrous proteins that associate with the flagellar membrane, namely, the sexual agglutinins and the protomers of a structure we designate a "hammock." They are also homologous to some of the fibrous components found in the extracellular matrices of multicellular plants and animals. The quick-freeze, deep-etch technique is demonstrated to be a highly informative way to dissect the structure of a fibrous matrix and visualize its component macromolecules.

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38

Fujioka-Kobayashi, Masako, Elena Andrejova, Hiroki Katagiri, Benoit Schaller, Anton Sculean, Jean-Claude Imber, Niklaus P. Lang, and Nikola Saulacic. "Impact of Cross-Linking of Collagen Matrices on Tissue Regeneration in a Rabbit Calvarial Bone Defect." Materials 14, no. 13 (July 4, 2021): 3740. http://dx.doi.org/10.3390/ma14133740.

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The cross-linking of collagen matrices (Cl_CM) may provide volume-stable enhanced defect regeneration when compared to non-cross-linked matrices (Ncl_CM). The aim of the present study was to investigate the bone forming potential of collagen matrices (CMs) and the effects of cross-linking CMs in a rabbit calvaria defect model. (1) Empty controls (n = 6), (2) Ncl_CM (n = 8), and (3) Cl_CM (n = 8) were selected to be observed for the healing in 10 mm critical-sized calvarial bone defects. The potential for the bone as well as the connective tissue formation were evaluated by micro-CT and histomorphometry at three months post-surgery. There were no statistically significant differences in terms of new bone volume in the defects between the groups. However, the Cl_CM induced significantly greater fibrous tissue regeneration (5.29 ± 1.57 mm2) when compared to the controls (3.51 ± 0.93 mm2) by histomorphometry. The remnants of collagen fibers with immune cells, including macrophages and giant cells, were occasionally observed in the Cl_CM group but not in the Ncl_CM group. In conclusion, the cross-linking of collagen did not influence the potential for bone formation. Nevertheless, Cl_CM might be advantageous for the maintenance of fibrous tissue volume without disturbing bone formation in the defects.

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39

Kohse, Stefanie, Daniela Arbeiter, Thomas Reske, Michael Stiehm, Klaus-Peter Schmitz, and Niels Grabow. "Electrospinning for polymeric implants in cardiovascular applications." Current Directions in Biomedical Engineering 4, no. 1 (September 1, 2018): 89–92. http://dx.doi.org/10.1515/cdbme-2018-0023.

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AbstractElectrospinning is a method for producing fibrous polymer scaffolds that can be applied in drug delivery systems as well as for polymer-based implants. Biodegradable polymers for the purpose of cardiac tissue engineering are often applied as fibrous scaffolds for morphological mimikry of natural matrices but also drugeluting approaches are very promising. Hydrolytic degradation is one of the key parameters for successful application. The focus of our investigations is on monitoring accelerated in vitro degradation of electrospun nonwoven scaffolds. In the presented study degradation of poly(Llactide) is accelerated by alkaline hydrolysis. The process is characterized by weight loss, loss of molecular mass, surface morphology and thermal behavior of nonwoven samples, showing a fast degradation of the fibrous material within two weeks.

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40

Смирнова, Н. В., И. Ю. Сапурина, М. А. Шишов, К. А. Колбе, Е. М. Иванькова, В. В. Матреничев, and В. Е. Юдин. "Композитные матрицы на основе сополиамида и полипиррола для тканевой инженерии." Журнал технической физики 90, no. 10 (2020): 1644. http://dx.doi.org/10.21883/jtf.2020.10.49794.42-20.

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It was demonstrated that conducting polymers can be used in development of bioactive matrices for tissue engineering. The most promising conducting polymer for biomedical applications is polypyrrole. Due to a number of useful properties, polypyrrole can be used in designing “smart” biologically active materials. In order to improve mechanical properties of the composite matrices, aliphatic copolyamide was used. Thin polymeric films were obtained from solution of this copolyamide; the solution was also used in preparation of non-woven fibrous mats by electrospinning. Copolyamide films were modified with pyrrole in the process of its oxidative polymerization to give the desired composite matrices. The obtained samples demonstrated suitable performance characteristics and a sufficient conductivity level for cell technologies. In vitro experiments showed that the matrices based on copolyamide and polypyrrole provide good survivability, adhesion and proliferation of human dermal fibroblasts.

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Sachot, Nadège, Oscar Castaño, Miguel A. Mateos-Timoneda, Elisabeth Engel, and Josep A. Planell. "Hierarchically engineered fibrous scaffolds for bone regeneration." Journal of The Royal Society Interface 10, no. 88 (November 6, 2013): 20130684. http://dx.doi.org/10.1098/rsif.2013.0684.

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Surface properties of biomaterials play a major role in the governing of cell functionalities. It is well known that mechanical, chemical and nanotopographic cues, for example, influence cell proliferation and differentiation. Here, we present a novel coating protocol to produce hierarchically engineered fibrous scaffolds with tailorable surface characteristics, which mimic bone extracellular matrix. Based on the sol–gel method and a succession of surface treatments, hollow electrospun polylactic acid fibres were coated with a silicon–calcium–phosphate bioactive organic–inorganic glass. Compared with pure polymeric fibres that showed a completely smooth surface, the coated fibres exhibited a nanostructured topography and greater roughness. They also showed improved hydrophilic properties and a Young's modulus sixfold higher than non-coated ones, while remaining fully flexible and easy to handle. Rat mesenchymal stem cells cultured on these fibres showed great cellular spreading and interactions with the material. This protocol can be transferred to other structures and glasses, allowing the fabrication of various materials with well-defined features. This novel approach represents therefore a valuable improvement in the production of artificial matrices able to direct stem cell fate through physical and chemical interactions.

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Gurave, Pramod M., Bhanu Nandan, and Rajiv K. Srivastava. "Emulsion templated dual crosslinked core-sheath fibrous matrices for efficient oil/water separation." Colloids and Surfaces A: Physicochemical and Engineering Aspects 635 (February 2022): 128037. http://dx.doi.org/10.1016/j.colsurfa.2021.128037.

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Ol’khov, A. A., E. L. Kucherenko, R. Yu Kosenko, V. S. Markin, V. I. Perov, and A. L. Iordanskii. "Analysis of the Structure of Polyhydroxybutyrate-Based Fibrous Matrices for Prolonged Drug Release." Inorganic Materials: Applied Research 10, no. 4 (July 2019): 806–11. http://dx.doi.org/10.1134/s2075113319040300.

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Kumar, Surjith, Takahiro Ito, Yuki Yanagihara, Yuya Oaki, Tatsuya Nishimura, and Takashi Kato. "Crystallization of unidirectionally oriented fibrous calcium carbonate on thermo-responsive polymer brush matrices." CrystEngComm 12, no. 7 (2010): 2021. http://dx.doi.org/10.1039/b923049a.

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Huang, Ching-Cheng. "Characteristics and Preparation of Designed Alginate-Based Composite Scaffold Membranes with Decellularized Fibrous Micro-Scaffold Structures from Porcine Skin." Polymers 13, no. 20 (October 9, 2021): 3464. http://dx.doi.org/10.3390/polym13203464.

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Alginate-based composite scaffold membranes with various ratios of decellularized extracellular matrices could be designed and obtained from porcine skin tissue by using supercritical carbon dioxide fluid technology. Retention of decellularized extracellular matrix (dECM) and scaffold-structure integrity was observed. This work provides a simple and time-saving process for the preparation of biomedical alginate-based composite scaffold membranes with fibrous dECM micro-scaffolds, which were further characterized by Fourier transform infrared spectroscopy (FTIR), thermo-gravimetric analysis (TGA), and scanning electron microscope (SEM). The introduction of fibrous dECM micro-scaffolds enhanced the thermal stability and provided expected effects on the biological properties of the designed composite scaffold membranes in regenerative applications.

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Olkhov, A. A., P. M. Tyubaeva, and A. L. Iordansky. "Structure and Properties of Fibrous Materials Based on Poly(-3-Hydroxybutyrate)." Materials Science Forum 992 (May 2020): 375–79. http://dx.doi.org/10.4028/www.scientific.net/msf.992.375.

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The article studies the supramolecular structure of polymer matrices for sustained isolation of drugs based on ultrathin fibers of polyhydroxybutyrate obtained by electrospinning method. Dipyridamole was chosen as a model drug. The concentration of dipyridamole in the fibers ranged from 1 to 5%. The morphology of nonwoven fibrous materials was investigated by scanning electron microscopy, differential scanning calorimetry, electron paramagnetic resonance. It was shown that the addition of the dipyridamole leads to a change in the fiber geometry. Fibers based on polyhydroxybutyrate are characterized by non-equilibrium molecular structure. In the current work, it was found that the addition of dipyridamole causes extra crystallization processes and the molecular mobility in the amorphous regions of the polymer slows down

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Ng, Robin, Jesse Singh Gurm, and Shang-Tian Yang. "Benzalkonium Chloride Sterilization of Nonwoven Fibrous Scaffolds for Astrocyte Culture." Open Biotechnology Journal 3, no. 1 (July 16, 2009): 73–78. http://dx.doi.org/10.2174/1874070700903010073.

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Tissue engineering is an emerging field in biomedicine, holding enormous promise for regenerative medicine. Scaffolds, within which cells proliferate, are a controlling factor in tissue engineering applications. Upon fabrication, tissue scaffolds must undergo appropriate sterilization to eliminate contaminants. Current sterilization methods are either costly, time consuming, or ineffective. In this study, a quaternary salt, benzalkonium chloride (BAC), was used as a chemical agent for sterilization of nonwoven polyethylene terephthalate (PET) fibers and polylactic acid nanofibers. Treating the PET scaffolds with 0.1% (w/v) BAC for only 2 minutes was effective to eliminate bacterial contaminants in the fibrous matrices. In addition, astrocyte cells were successfully cultured in the PET scaffolds following BAC sterilization, demonstrating the suitability of BAC as a sterilization agent. This chemical sterilization method is also mild and nonabrasive to nanostructured materials such as electrospun polylactic acid nanofibers.

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Mironov, Viktor, Yulia Usherenko, Pavels Stankevich, and Elina Barone. "Compaction of Powdered Materials Reinforced with Milled W-B Fibers." Key Engineering Materials 721 (December 2016): 275–79. http://dx.doi.org/10.4028/www.scientific.net/kem.721.275.

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Fibrous composite materials with metal matrices are effectively employed in the newest technical fields. Researches related to the development of composite materials, containing W-B fibers are among them. Fibrous composite materials are effectively used in newest technical industries because of their high durability, small weight and other valuable properties. The paper describes the features of grinding Al-W-B waste using a disintegrator to obtain W-B fiber powder with a specified particle size. A number of mixtures with the metal substrate are offered. Methods for preparing samples of various compositions containing W-B fibers are observed. Results of research of physical-mechanical, tribological properties and microstructure of materials are brought.

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Ashrafi, Zahra, Zimu Hu, Lucian Lucia, and Wendy Krause. "Bacterial Superoleophobic Fibrous Matrices: A Naturally Occurring Liquid-Infused System for Oil–Water Separation." Langmuir 37, no. 8 (February 19, 2021): 2552–62. http://dx.doi.org/10.1021/acs.langmuir.0c02717.

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Tang, Yanwei, Cynthia Wong, Hongxia Wang, Alessandra Sutti, Mark Kirkland, Xungai Wang, and Tong Lin. "Three-Dimensional Tissue Scaffolds from Interbonded Poly(ε-Caprolactone) Fibrous Matrices with Controlled Porosity." Tissue Engineering Part C: Methods 17, no. 2 (February 2011): 209–18. http://dx.doi.org/10.1089/ten.tec.2010.0223.

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