Academic literature on the topic 'Fibrosis Assessment'

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Journal articles on the topic "Fibrosis Assessment"

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Virarkar, Mayur, Ajaykumar C. Morani, Melissa W. Taggart, and Priya Bhosale. "Liver Fibrosis Assessment." Seminars in Ultrasound, CT and MRI 42, no. 4 (2021): 381–89. http://dx.doi.org/10.1053/j.sult.2021.03.003.

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Loomba, Rohit, and Leon A. Adams. "Advances in non-invasive assessment of hepatic fibrosis." Gut 69, no. 7 (2020): 1343–52. http://dx.doi.org/10.1136/gutjnl-2018-317593.

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Liver fibrosis should be assessed in all individuals with chronic liver disease as it predicts the risk of future liver-related morbidity and thus need for treatment, monitoring and surveillance. Non-invasive fibrosis tests (NITs) overcome many limitations of liver biopsy and are now routinely incorporated into specialist clinical practice. Simple serum-based tests (eg, Fibrosis Score 4, non-alcoholic fatty liver disease Fibrosis Score) consist of readily available biochemical surrogates and clinical risk factors for liver fibrosis (eg, age and sex). These have been extensively validated acros
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Masuzaki, Ryota, Tatsuo Kanda, Reina Sasaki, et al. "Noninvasive Assessment of Liver Fibrosis: Current and Future Clinical and Molecular Perspectives." International Journal of Molecular Sciences 21, no. 14 (2020): 4906. http://dx.doi.org/10.3390/ijms21144906.

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Liver fibrosis is one of the risk factors for hepatocellular carcinoma (HCC) development. The staging of liver fibrosis can be evaluated only via a liver biopsy, which is an invasive procedure. Noninvasive methods for the diagnosis of liver fibrosis can be divided into morphological tests such as elastography and serum biochemical tests. Transient elastography is reported to have excellent performance in the diagnosis of liver fibrosis and has been accepted as a useful tool for the prediction of HCC development and other clinical outcomes. Two-dimensional shear wave elastography is a new techn
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Mik, Patrik, Katsiaryna Barannikava, and Polina Surkova. "Biased Quantification of Rat Liver Fibrosis—Meta-Analysis with Practical Recommendations and Clinical Implications." Journal of Clinical Medicine 12, no. 15 (2023): 5072. http://dx.doi.org/10.3390/jcm12155072.

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For liver fibrosis assessment, the liver biopsy is usually stained with Masson’s trichrome (MT) or picrosirius red (PSR) to quantify liver connective tissue (LCT) for fibrosis scoring. However, several concerns of such semiquantitative assessments have been raised, and when searching for data on the amount of LCT in healthy rats, the results vastly differ. Regarding the ongoing reproducibility crisis in science, it is necessary to inspect the results and methods, and to design an unbiased and reproducible method of LCT assessment. We searched the Medline database using search terms related to
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Castera, Laurent. "Noninvasive Assessment of Liver Fibrosis." Digestive Diseases 33, no. 4 (2015): 498–503. http://dx.doi.org/10.1159/000374097.

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Background: The prognosis and management of chronic liver diseases greatly depend on the amount and progression of liver fibrosis with the risk of developing cirrhosis. Liver biopsy, traditionally considered as the reference standard for the staging of fibrosis, has been challenged over the past decade by the development of novel noninvasive methodologies. Key Messages: Noninvasive methods rely on two different but complementary approaches: a ‘biological' approach based on the dosage serum biomarkers, and a ‘physical' approach based on the measurement of liver stiffness using transient elastog
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Mesa, Ruben A. "Detangling fibrosis assessment in MPNs." Leukemia Research 34, no. 7 (2010): 854–55. http://dx.doi.org/10.1016/j.leukres.2010.01.014.

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Hall, P. de la M., M. A. Jenner, L. R. Jarvis, and M. Ahern. "Morphometric assessment of hepatic fibrosis." Pathology 23 (1991): 2. http://dx.doi.org/10.1016/s0031-3025(16)36166-9.

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Jellis, Christine, Jennifer Martin, Jagat Narula, and Thomas H. Marwick. "Assessment of Nonischemic Myocardial Fibrosis." Journal of the American College of Cardiology 56, no. 2 (2010): 89–97. http://dx.doi.org/10.1016/j.jacc.2010.02.047.

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Kelleher, T. Barry, and Nezam Afdhal. "Noninvasive Assessment of Liver Fibrosis." Clinics in Liver Disease 9, no. 4 (2005): 667–83. http://dx.doi.org/10.1016/j.cld.2005.08.002.

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Bonder, Alan, Elliot B. Tapper, and Nezam H. Afdhal. "Contemporary Assessment of Hepatic Fibrosis." Clinics in Liver Disease 19, no. 1 (2015): 123–34. http://dx.doi.org/10.1016/j.cld.2014.09.007.

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Dissertations / Theses on the topic "Fibrosis Assessment"

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Meloff, Liann Rachel. "Assessment of eating disorder symptomatology in patients with cystic fibrosis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ64876.pdf.

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Bradley, Judith. "The assessment of disability and handicap in adult cystic fibrosis." Thesis, University of Ulster, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311617.

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Jaffe, Adam. "Assessment and feasibility of gene therapy for cystic fibrosis in children." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589769.

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Adam, Ryan John. "Quantitative morphologic assessment of the newborn cystic fibrosis pig tracheal lobe." Thesis, University of Iowa, 2012. https://ir.uiowa.edu/etd/2807.

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Cystic fibrosis (CF) is an inherited disease leading to disrupted function of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel. CF affects many organ systems including the pancreas, liver, intestine, sweat glands, and gallbladder. The leading cause of morbidity and mortality, however, is lung disease. A porcine model of CF was developed, and over time it develops lung disease that recapitulates many of the characteristics observed in humans with CF including airway remodeling, mucus accumulation
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Adam, Ryan J. "Radiographic assessment of lung anatomy, physiology, and disease in a porcine model of cystic fibrosis and people with cystic fibrosis." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5692.

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Despite affecting many organ systems, the leading cause of morbidity and mortality in the cystic fibrosis (CF) population is lung disease. For the current studies we investigated elements of CF lung disease in a porcine model of CF and in people with CF. Our primary analysis tool was chest computed tomography (CT). To investigate early CF lung disease we examined three week old CF and non-CF pigs. We found three week old CF pigs to have large, irregular tracheal smooth muscle bundles, airways of reduced size, airways of irregular shape, and airways of abnormal distensibility. Three week old CF
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Olveda, David Brian Uy. "Assessment of Schistosomiasis Induced Morbidity in the Philippines." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/368011.

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Schistosomiasis is a water-borne tropical disease plaguing approximately 240 million people worldwide. Approximately 3-70 million disability-adjusted life years are lost due to the disease. In the Philippines, schistosomiasis japonica is currently endemic in 28 provinces, 190 municipalities, and 2230 barangays (villages). Approximately 12 million residents of these endemic areas are vulnerable to infection. Preventive chemotherapy with praziquantel has been the cornerstone for schistosomiasis control in the country. The current national control program comprises annual free mass drug administr
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Guha, Indra Neil. "Exploring the diagnostic tools for the assessment of liver fibrosis using biofluids." Thesis, University of Southampton, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443044.

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Gangell, Catherine Louise. "Evaluation of the forced oscillation technique for clinical assessment of young children with cystic fibrosis." University of Western Australia. School of Paediatrics and Child Health, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0213.

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Background: Measurements of lung function are routinely used in patients with cystic fibrosis (CF) to provide information that may be clinically relevant. Spirometry is the conventional lung function measurement used, however young children find spirometry difficult to perform and often cannot achieve the strict acceptability criteria for the test. The forced oscillation technique (FOT) is a lung function measurement that only requires tidal breathing and is easy for young children to perform. However, there is limited information about the utility of this technique in the clinical assessment
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Gray, Robert Donald. "Non-invasive biomarkers of inflammation in the assessment of cystic fibrosis lung disease." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/24641.

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Cystic fibrosis (CF) is the most common fatal inherited single gene defect in Caucasian populations. CF lung disease is characterised by infection, inflammation and progressive lung destruction. Lung inflammation is measurable in CF patients even with early disease. Gene therapy offers a theoretical cure for CF lung disease, with large clinical trials now being planned. There is not only a clear need for the development of new therapies in CF but also the means to measure the success of these therapies. One possible approach is to measure biomarkers of airway inflammation non-invasively (in sp
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Karlas, Thomas, and Johannes Wiegand. "Non-Invasive Assessment of Hepatic Steatosis in Patients with NAFLD Using Controlled Attenuation Parameter and 1H-MR Spectroscopy." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-142654.

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Introduction: Non-invasive assessment of steatosis and fibrosis is of growing relevance in non-alcoholic fatty liver disease (NAFLD). 1H-Magnetic resonance spectroscopy (1H-MRS) and the ultrasound-based controlled attenuation parameter (CAP) correlate with biopsy proven steatosis, but have not been correlated with each other so far. We therefore performed a headto- head comparison between both methods. Methods: Fifty patients with biopsy-proven NAFLD and 15 healthy volunteers were evaluated with 1H-MRS and transient elastography (TE) including CAP. Steatosis was defined according to the percen
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Books on the topic "Fibrosis Assessment"

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Bradley, Judith M. The assessment of disability and handicap in adult cystic fibrosis. The Author], 1999.

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Chern, E. James. Assessment of probability of detection of delaminations in fiber-reinforced composites. National Aeronautics and Space Administration, Goddard Space Flight Center, 1991.

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Heather, Nicky. Nutritional management of cystic fibrosis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759928.003.0024.

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This chapter covers the nutritional management of cystic fibrosis. This includes discussion of the risk factors for malnutrition, assessment of nutritional status, assessment of nutritional requirements, and practical management. The chapter includes a section on pancreatic enzyme replacement therapy.
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Dilsizian, Vasken, Ines Valenta, and Thomas H. Schindler. Myocardial Viability Assessment. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0021.

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Heart failure may be a consequence of ischemic or non-ischemic cardiomyopathy. Etiologies for LV systolic dysfunction in ischemic cardiomyopathy include; 1) transmural scar, 2) nontransmural scar, 3) repetitive myocardial stunning, 4) hibernating myocardium, and 5) remodeled myocardium. The LV remodeling process, which is activated by the renin-angiotensin system (RAS), stimulates toxic catecholamine actions and matrix metalloproteinases, resulting in maladaptive cellular and molecular alterations5, with a final pathway to interstitial fibrosis. These responses to LV dysfunction and interstiti
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US GOVERNMENT. Cystic Fibrosis and DNA Tests: Implications of Carrier Screening. Office of Technology Assessment, 1992.

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Bowker, Lesley K., James D. Price, Ku Shah, and Sarah C. Smith. Chest medicine. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198738381.003.0011.

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This chapter provides information on the ageing lung, respiratory infections, influenza, pneumonia, pneumonia treatment, vaccinating against pneumonia and influenza, pulmonary fibrosis, rib fractures, pleural effusions, pulmonary embolism, aspiration pneumonia/pneumonitis, lung cancers, chronic cough, presentation of tuberculosis, tuberculosis investigation, treatment of tuberculosis, assessment of asthma and chronic obstructive pulmonary disease (COPD), drug treatment of asthma and COPD, non-drug treatment of asthma and COPD, oxygen therapy, and asbestos-related disease.
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Voilliot, Damien, Jaroslaw D. Kasprzak, and Eduardo Bossone. Diseases with a main influence on right ventricular function. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0060.

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As an important and independent predictive factor of morbidity and mortality, right ventricular (RV) function should be carefully assessed in patients with chronic obstructive lung disease, lung fibrosis, liver cirrhosis, or obesity. RV assessment requires a complete study of the ‘RV-pulmonary circulation unit’ with estimation of RV preload, RV intrinsic contractility, and RV afterload. Therefore, estimation of pulmonary arterial pressure, pulmonary vascular resistance, and left ventricular systolic and diastolic function should be included in this evaluation, in addition to conventional RV sy
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Millar, Professor Ann B., Dr Richard Leach, Dr Rebecca Preston, et al. Respiratory diseases and respiratory failure. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199565979.003.0005.

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Chapter 5 covers respiratory diseases and respiratory failure, including clinical presentations of respiratory disease, assessment of diffuse lung disease, hypoxaemia, respiratory failure, and oxygen therapy, pneumonia, mycobacterial infection, asthma, chronic obstructive pulmonary disease (COPD), lung cancer, mediastinal lesions, pneumothorax, pleural disease, asbestos-related lung disease, diffuse parenchymal (interstitial) lung disease, sarcoidosis, pulmonary hypertension, acute respiratory distress syndrome, bronchiectasis and cystic fibrosis, bronchiolitis, eosinophilic lung disease, airw
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Sierakowski, Adam, David Warwick, and Roderick Dunn. Vascular. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757689.003.0018.

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Vascular pathology in the hand may present to many different specialties, and delayed referral to hand specialists is not unusual. We provide an overview of vascular hand anatomy and pathophysiology to enable early diagnosis and treatment. We discuss general assessment of vascular hand pathology, including vascular anomalies, vascular injury, and Raynaud’s disease. It is important to understand the diagnosis and emergency surgical treatment of compartment syndrome of the upper limb which if unrecognized can lead to permanent loss of function from post-ischaemic fibrosis (and may be less antici
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Herbert, Lara, and Bruce McCormick. Respiratory disease. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198719410.003.0005.

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This chapter describes the anaesthetic management of the patient with respiratory disease. It describes the assessment of respiratory function and preoperative respiratory investigations, and ventilatory strategies to reduce pulmonary complications. Common respiratory conditions covered include respiratory tract infection, smoking, asthma, chronic obstructive pulmonary disease, bronchiectasis, cystic fibrosis, obstructive sleep apnoea, sarcoidosis, restrictive pulmonary disease, and the patient with a transplanted lung. For each topic, preoperative investigation and optimization, treatment, an
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Book chapters on the topic "Fibrosis Assessment"

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Kumar, Rakesh K. "Morphological Methods for Assessment of Fibrosis." In Fibrosis Research. Humana Press, 2005. http://dx.doi.org/10.1385/1-59259-940-0:179.

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John, Alison E., Joanne Porte, Gisli Jenkins, and Amanda L. Tatler. "Methods for the Assessment of Active Transforming Growth Factor-β in Cells and Tissues." In Fibrosis. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7113-8_23.

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Klein, Sabine, Robert Schierwagen, Frank Erhard Uschner, and Jonel Trebicka. "Mouse and Rat Models of Induction of Hepatic Fibrosis and Assessment of Portal Hypertension." In Fibrosis. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7113-8_7.

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Fulton, Judith A., and Alexandra W. M. Wilson. "Nutrition Assessment: Adults and Obesity." In Nutrition in Cystic Fibrosis. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16387-1_8.

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Maguiness, Karen, and Molly Bozic. "Nutritional Assessment: Age 2–20 Years." In Nutrition in Cystic Fibrosis. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16387-1_7.

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Xiao, Guangqin, and Lunan Yan. "Liver Fibrosis and Its Assessment." In Operative Techniques in Liver Resection. Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-017-7411-6_5.

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de Ledinghen, Victor. "Fibrosis Assessment in Patients with NAFLD." In Liver Elastography. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40542-7_10.

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Majumdar, Avik, and Massimo Pinzani. "Non-invasive Assessment of Fibrosis and Cirrhosis." In Sherlock's Diseases of the Liver and Biliary System. John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781119237662.ch7.

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Denzer, U. W. "Assessment of liver fibrosis: gold standard biopsy?" In Liver under Constant Attack — From Fat to Viruses. Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2759-7_17.

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Wielpütz, Mark O. "Functional Assessment of Cystic Fibrosis Lung Disease." In Medical Radiology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-43539-4_10.

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Conference papers on the topic "Fibrosis Assessment"

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Lee, Jaeyul, Sreyankar Nandy, Sarita R. Berigei, et al. "In-vivo collagen orientation assessment to predict progression in idiopathic pulmonary fibrosis using polarization-sensitive endobronchial optical coherence tomography." In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIX, edited by Rainer A. Leitgeb and Yoshiaki Yasuno. SPIE, 2025. https://doi.org/10.1117/12.3046396.

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Laudus, Nele, Celia Badenas, Heike Torkler, et al. "Exploring the knowledge of genetics laboratories on CFTR modulator therapy eligibility: findings and reflections during external quality assessment." In Adult Cystic Fibrosis Conference abstracts. European Respiratory Society, 2023. http://dx.doi.org/10.1183/23120541.acf-2023.7.

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Roach, KM, P. Tongue, E. Castells, et al. "S88 A human model of lung fibrosis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis." In British Thoracic Society Winter Meeting 2019, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 4 to 6 December 2019, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2019. http://dx.doi.org/10.1136/thorax-2019-btsabstracts2019.94.

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Sharma, B. S. Mahima, and N. Sujatha. "Assessment of skin fibrosis using Mueller matrix polarimetry." In 2018 3rd International Conference on Microwave and Photonics (ICMAP). IEEE, 2018. http://dx.doi.org/10.1109/icmap.2018.8354544.

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Cirstea, Olga, Oxana Turcu, and Ala Jivalcovschi. "P339 Nutritional status assessment in children with cystic fibrosis." In 8th Europaediatrics Congress jointly held with, The 13th National Congress of Romanian Pediatrics Society, 7–10 June 2017, Palace of Parliament, Romania, Paediatrics building bridges across Europe. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2017. http://dx.doi.org/10.1136/archdischild-2017-313273.427.

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Mylavarapu, G., R. J. Fleck, M. Hossain, M. DiFrancesco, J. C. Woods, and R. S. Amin. "Assessment of Pulmonary Vascular Morphology in Cystic Fibrosis Patients." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7440.

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Morimoto, David, Kathleen M. Keehan, Paul E. Kilbride, and Norman P. Blair. "Retinal Reattachment of the Human Macula Assessed by Imaging Fundus Reflectometry." In Noninvasive Assessment of the Visual System. Optica Publishing Group, 1990. http://dx.doi.org/10.1364/navs.1990.tha4.

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Visual recovery following retinal reattachment surgery may be limited by a number of factors. Detachment of the macula is the most important of these, often yielding poor visual acuity after an anatomic success. Gross morphologic changes giving a poor visual result include macular pucker, cellophane maculopathy, cystoid macular edema, and subretinal fibrosis. Some cases with a normal appearing macula by ophthalmoscopy have reduced visual acuity, and these have been attributed to misalignment of photoreceptors, faulty regeneration of photoreceptors, or RPE atrophy (4,5,6). Histologic animal stu
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McPherson, Stuart, Jessica Dyson, Laura Jopson, Steven Masson, Preya Patel, and Quentin Anstee. "P19 How effective is a ‘clinical fibrosis assessment’ using non-invasive fibrosis tests in patients with NAFLD?" In Abstracts of the British Association for the Study of the Liver Annual Meeting, 19–22 September 2023. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2023. http://dx.doi.org/10.1136/gutjnl-2023-basl.35.

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Weingartner, Sebastian, Omer Burak Demirel, Chetan Shenoy, Lothar R. Schad, Jeanette Schulz-Menger, and Mehmet Akcakaya. "Functional LGE Imaging: Cardiac Phase-Resolved Assessment of Focal Fibrosis." In 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2019. http://dx.doi.org/10.1109/embc.2019.8857759.

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Nouha, Ayadi, Feki Walid, Marrakchi Rim, et al. "Assessment of nutritional status in patients with idiopathic pulmonary fibrosis." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa3703.

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Reports on the topic "Fibrosis Assessment"

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Kofinova, Denica, Raina Shentova-Eneva, Petyo Hadzhiyski, et al. Twodimensional Shear-wave Elastography for Assessment of Liver Fibrosis in Children. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2021. http://dx.doi.org/10.7546/crabs.2021.10.17.

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Ultrasound Measurement of Shear Wave Speed for Estimation Liver Fibrosis, Clinically Feasible Profile. Chair David Fetzer, Stephen McAleavey, and Stephen Rosenzweig. Radiological Society of North America (RSNA) / Quantitative Imaging Biomarkers Alliance (QIBA), 2024. http://dx.doi.org/10.1148/qiba/20240115.

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The goal of a QIBA Profile is to help achieve a useful level of performance for a given biomarker. Profile development is an evolutionary, phased process; this Profile is in the “Clinically Feasible” (formerly “Technically Confirmed") stage. The performance claims represent expert consensus and will be empirically demonstrated at a subsequent stage. Several sites have performed the profile, found it to be practical, and expect it to achieve the claimed performance. Users of this Profile are encouraged to refer to the following site to understand the document’s context: http://qibawiki.rsna.org
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Sowjanya, Dr Kaniti, Dr Bongu Srinivas, and Dr Metta Lakshmana Rao. A STUDY ON FIBROSCAN COMPARED TO AST TO PLATELET RATIO INDEX(APRI) FOR ASSESSMENT OF LIVER FIBROSIS WITH NONALCOHOLIC FATTY LIVER DISEASE(NAFLD). World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/1606016.

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Background : Nonalcoholic fatty liver disease (NAFLD) is increasingly recognized as a cause of chronic liver disease, and often results in the devastating outcomes of decompensated liver cirrhosis and hepatocellular carcinoma and is an important feature of metabolic syndromes and insulin resistance. The assessment of liver brosis is essential for predicting the prognosis and outcome of all forms of chronic liver disease. A liver biopsy is the gold standard for the assessment of liver brosis, but it has its limitations, which include life-threatening complications. Alternative methods of non-
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Pepin, Kay, ed. MR Elastography of the Liver, Clinically Feasible Profile. Chair Richard Ehman and Patricia Cole. Radiological Society of North America (RSNA) / Quantitative Imaging Biomarkers Alliance (QIBA), 2023. http://dx.doi.org/10.1148/qiba/20231107.

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The goal of a QIBA Profile is to help achieve a useful level of performance for a given biomarker. The Claim (Section 2) describes the biomarker performance. The Activities (Section 3) contribute to generating the biomarker. Requirements are placed on the Actors that participate in those activities as necessary to achieve the Claim. Assessment Procedures (Section 4) for evaluating specific requirements are defined as needed. This QIBA Profile (Magnetic Resonance Elastography of the Liver) addresses the application of Magnetic Resonance Elastography (MRE) for the quantification of liver stiffne
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