Academic literature on the topic 'Fibre biophotonique'
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Journal articles on the topic "Fibre biophotonique":
Provino, Laurent, Achille Monteville, David Landais, Olivier Le Goffic, Adil Haboucha, Thiery Taunay, and David Mechin. "Les fibres microstructurées : 20 ans d’existence et un vaste éventail d’applications." Photoniques, no. 99 (November 2019): 40–44. http://dx.doi.org/10.1051/photon/20199940.
Lebrun, Sylvie. "Convertisseurs de longueurs d’onde à fibres à coeur liquide pour la biophotonique." Photoniques, no. 54 (July 2011): 34–37. http://dx.doi.org/10.1051/photon/20115434.
Dissertations / Theses on the topic "Fibre biophotonique":
Manesco, Clara. "Etude photonique et nano-mécanique pour le suivi sans marquage de la cicatrice fibrotique dans les lésions de la moelle épinière chez la souris." Electronic Thesis or Diss., Université de Montpellier (2022-....), 2023. http://www.theses.fr/2023UMONS072.
Spinal cord injuries (SCI) are part of the most impactful pathologies in the central nervous system (CNS). They can induce dramatic physical and psycho-social effects for the patients, associated with a consequent impact on the health care system. When an injury occurs, it induces a cascade of events disturbing the surrounding structures and cell populations, and includes the formation of a glial scar. This scar is composed of various cell populations such as activated microglial and astrocytes. Fibroblasts are producing collagen with the support of reactive astrocytes and are involved in the fibrotic process. The glial scar is a dense chemical and physical barrier with dual effects on the recovery. No curative treatment is currently available. However, promising pharmaceutical approaches have been developed through the transient depletion of microglia using a GW2580 treatment, an inhibitor of CSF1R receptor that specifically regulates the proliferative part of microglial cells.The exploration of collagen in the glial scar formation has raised poor attention comparing to the interest in microglia and astrocytes roles. Fibrillar collagen as collagen I is well known in common wound healing processes occurring in the rest of the body, and is defined by a supramolecular organization in cross-striated fibril shaped into a cylindrical structure and eventually associated into fibers. This assembly leads to unique optical properties that can be directly monitored by non-linear optical measurements (NLO), such as Second Harmonic Generation (SHG), without special sample preparation and without any exogenous labeling. As SHG is a coherent signal that depends on the polarization of the incident laser by performing Polarization-resolved SHG (P-SHG) collagen fibers arrangement at a supramolecular level can be assessed related to the fibrils nature (related to their symmetry profiles).The global approach proposed in our work was to exploit the potential of NLO optics in detecting and characterizing fibrillar collagen in SCI (using Multiphoton microscopy to visualize simultaneously 2-photon excited fluorescence and SHG signals) in a mouse model and to correlate the structural information to the biomechanical behavior of the tissue via micro/nano-indentation force measurements with Atomic Force Microscopy (AFM). Collagen fibers exhibited by their SHG signal were characterized with two methods: CurveAlign software dedicated to collagen fibers analysis in biological samples and a home-build Fingerprint algorithm establishing an analysis pipeline more adapted to our study. We eventually generated a skeleton map of the fibers to extract relevant metrics such as the fibers’ density, tortuosity and orientation at local level (calculating the circular variance of the local orientation) and at global level (calculating the statistical entropy). Our multimodal label-free imaging approach was thus dedicated to reveal and monitor lesion biomarkers from the fibrotic structure and the elasticity of injured spinal cord tissues after various time-points post-injury and to investigate the potential effect of a pharmacological treatment with GW2580 at 6 weeks post injury. The SHG signal exhibited by fibrillar collagen enabled to specifically monitor it as a biomarker of the lesion. An increase in collagen fibers density and the formation of more tortuous fibers overtime from 1 week to 6 weeks post-injury was observed. P-SHG measurements revealed both fibrils symmetry types (cylindrical and trigonal) at all the time-points post injury. Nano-mechanical investigations revealed a noticeable hardening of the injured area from 1week post injury, correlated with collagen fibers’ formation.These observations indicate the concomitance of important structural and mechanical modifications during the fibrotic scar evolution following a spinal cord injury in mice
Hongisto, Mikko. "Développement de verres et vitrocéramiques dopés ytterbium pour l'optique et réponses sous différents types de traitements." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0040.
This thesis studies the modification of the properties of glass compounds doped with Yb3+ ions, through variations in composition, thermal or radiation treatments as well as by immersion in aqueous medium. New Yb3+ doped oxyfluorophosphate glass/glass-ceramics have been developed and characterized to obtain fundamental information on crystallization. The study also proposes the development of cylindrical and rectangular bioactive fibers based on doped and non-doped borosilicate glass constituting the core and the clad of the fiber respectively. The stability of these fibers in aqueous medium is monitored according to the geometry. This study also provides information on resistance to defects depending on the nature of the network and on the development of new bioactive fibers, the emission of which could be used to follow the dissolution of the fiber in aqueous medium. This study contributes to a better fundamental understanding of how composition changes and thermal/radiation processes can modulate the performance parameters of glass materials doped by Yb3+ ions
Andreana, Marco. "Propagation Solitonic dans les cristaux et les fibres optiques." Limoges, 2011. https://aurore.unilim.fr/theses/nxfile/default/33a22eec-eaee-4bdc-8bf4-6f133334fd3f/blobholder:0/2011LIMO4032.pdf.
In spectroscopy, as well as in many futuristic applications in biophotonics, the managing of time delays between different wavelengths interacting via the non-linearity may open a route towards new applications. In this manuscript the way to equalize and control group velocity of different wavelenghts is studied. The nonlinear control is related with the knowledge of self-sustained optical waveform called solitons. In crystals, new types of nonlinear solitonic and simultonic propagations by means of sumfrequency generation is studied. This unusual dynamics of propagation allows group velocity compensation between all the interacting waves