Journal articles on the topic 'FFA3'
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Priyadarshini, Medha, Guadalupe Navarro, and Brian T. Layden. "Gut Microbiota: FFAR Reaching Effects on Islets." Endocrinology 159, no. 6 (May 4, 2018): 2495–505. http://dx.doi.org/10.1210/en.2018-00296.
Full textSchmidt, Johannes, Nicola J. Smith, Elisabeth Christiansen, Irina G. Tikhonova, Manuel Grundmann, Brian D. Hudson, Richard J. Ward, et al. "Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists." Journal of Biological Chemistry 286, no. 12 (January 10, 2011): 10628–40. http://dx.doi.org/10.1074/jbc.m110.210872.
Full textBisenieks, Egils, Brigita Vigante, Ramona Petrovska, Baiba Turovska, Ruslan Muhamadejev, Vitalijs Soloduns, Astrida Velena, et al. "The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A." Pharmaceuticals 14, no. 10 (September 28, 2021): 987. http://dx.doi.org/10.3390/ph14100987.
Full textGough, Sophie, Brian Layden, Chioma Nnyamah, Medha Priyadarshini, Barton Wicksteed, and Kristen Lednovich. "OR23-4 Intestinal FFA2 and FFA3 Mediate Obesogenic Effects in Mice on a Western Diet." Journal of the Endocrine Society 6, Supplement_1 (November 1, 2022): A19. http://dx.doi.org/10.1210/jendso/bvac150.040.
Full textPriyadarshini, Medha, Connor Cole, Gautham Oroskar, Anton E. Ludvik, Barton Wicksteed, Congcong He, and Brian T. Layden. "Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 318, no. 4 (April 1, 2020): R691—R700. http://dx.doi.org/10.1152/ajpregu.00128.2019.
Full textZamarbide, Marta, Eva Martinez-Pinilla, Francisco Gil-Bea, Masashi Yanagisawa, Rafael Franco, and Alberto Perez-Mediavilla. "Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer’s Disease Mouse Model." International Journal of Molecular Sciences 23, no. 7 (March 24, 2022): 3533. http://dx.doi.org/10.3390/ijms23073533.
Full textLednovich, Kristen Roan, Sophie Gough, Medha Priyadarshini, and Brian T. Layden. "Loss of Intestine-Specific FFA3 Has Protective Effects Against Diet-Induced Obesity and Hyperglycemia in Mice on a Western Diet." Journal of the Endocrine Society 5, Supplement_1 (May 1, 2021): A441. http://dx.doi.org/10.1210/jendso/bvab048.901.
Full textVilla, Stephanie R., Rama K. Mishra, Joseph L. Zapater, Medha Priyadarshini, Annette Gilchrist, Helena Mancebo, Gary E. Schiltz, and Brian T. Layden. "Homology modeling of FFA2 identifies novel agonists that potentiate insulin secretion." Journal of Investigative Medicine 65, no. 8 (August 7, 2017): 1116–24. http://dx.doi.org/10.1136/jim-2017-000523.
Full textLednovlch, Kristen R., Sophie Gough, Medha Priyadarshini, and Brian Layden. "Tu1952 DEFINING THE ROLE OF INTESTINE-SPECIFIC FFA2 AND FFA3 IN HORMONAL SECRETION." Gastroenterology 158, no. 6 (May 2020): S—1231. http://dx.doi.org/10.1016/s0016-5085(20)33739-2.
Full textMikami, Daisuke, Mamiko Kobayashi, Junsuke Uwada, Takashi Yazawa, Kazuko Kamiyama, Kazuhisa Nishimori, Yudai Nishikawa, et al. "AR420626, a selective agonist of GPR41/FFA3, suppresses growth of hepatocellular carcinoma cells by inducing apoptosis via HDAC inhibition." Therapeutic Advances in Medical Oncology 12 (January 2020): 175883592091343. http://dx.doi.org/10.1177/1758835920913432.
Full textKaji, Izumi, Yasutada Akiba, Jonathan D. Kaunitz, Shin-ichiro Karaki, and Atsukazu Kuwahara. "Su1745 Differential Expression of Short-Chain Fatty Acid Receptor FFA2 and FFA3 in Foregut." Gastroenterology 142, no. 5 (May 2012): S—494. http://dx.doi.org/10.1016/s0016-5085(12)61887-3.
Full textMilligan, Graeme, Leigh A. Stoddart, and Nicola J. Smith. "Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3." British Journal of Pharmacology 158, no. 1 (September 2009): 146–53. http://dx.doi.org/10.1111/j.1476-5381.2009.00421.x.
Full textMikami, Daisuke, Mamiko Kobayashi, Junsuke Uwada, Takashi Yazawa, Kazuko Kamiyama, Kazuhisa Nishimori, Yudai Nishikawa, et al. "Short-chain fatty acid mitigates adenine-induced chronic kidney disease via FFA2 and FFA3 pathways." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1865, no. 6 (June 2020): 158666. http://dx.doi.org/10.1016/j.bbalip.2020.158666.
Full textTang, Cong, Kashan Ahmed, Andreas Gille, Shun Lu, Hermann-Josef Gröne, Sorin Tunaru, and Stefan Offermanns. "Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes." Nature Medicine 21, no. 2 (January 12, 2015): 173–77. http://dx.doi.org/10.1038/nm.3779.
Full textVaziri, Nosratola D., Ane C. F. Nunes, Hyder Said, Mahyar Khazaeli, Han Liu, Yitong Zhao, Wanghui Jing, Kyle Cogburn, Leila Alikhani, and Wei Ling Lau. "Route of intestinal absorption and tissue distribution of iron contained in the novel phosphate binder ferric citrate." Nephrology Dialysis Transplantation 35, no. 7 (June 8, 2020): 1136–44. http://dx.doi.org/10.1093/ndt/gfaa053.
Full textLymperopoulos, Anastasios, Malka S. Suster, and Jordana I. Borges. "Short-Chain Fatty Acid Receptors and Cardiovascular Function." International Journal of Molecular Sciences 23, no. 6 (March 18, 2022): 3303. http://dx.doi.org/10.3390/ijms23063303.
Full textKaji, Izumi, Yasutada Akiba, Kazuyuki Narimatsu, and Jonathan D. Kaunitz. "Tu1403 Neural FFA3 Activation Inversely Regulates Cholinergic Secretory Function in Rat Proximal Colon." Gastroenterology 148, no. 4 (April 2015): S—880. http://dx.doi.org/10.1016/s0016-5085(15)32990-5.
Full textHudson, Brian D., Irina G. Tikhonova, Sunil K. Pandey, Trond Ulven, and Graeme Milligan. "Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3." Journal of Biological Chemistry 287, no. 49 (October 12, 2012): 41195–209. http://dx.doi.org/10.1074/jbc.m112.396259.
Full textFreitas, Raquel D. S., Thaís C. Muradás, Ana Paula A. Dagnino, Fernanda L. Rost, Kesiane M. Costa, Gianina T. Venturin, Samuel Greggio, Jaderson C. da Costa, and Maria M. Campos. "Targeting FFA1 and FFA4 receptors in cancer-induced cachexia." American Journal of Physiology-Endocrinology and Metabolism 319, no. 5 (November 1, 2020): E877—E892. http://dx.doi.org/10.1152/ajpendo.00509.2019.
Full textAl Mahri, Saeed, Shuja Shafi Malik, Maria Al Ibrahim, Esraa Haji, Ghida Dairi, and Sameer Mohammad. "Free Fatty Acid Receptors (FFARs) in Adipose: Physiological Role and Therapeutic Outlook." Cells 11, no. 4 (February 21, 2022): 750. http://dx.doi.org/10.3390/cells11040750.
Full textPatti, Angelo Maria, Rosaria Vincenza Giglio, Nikolaos Papanas, Dragos Serban, Anca Pantea Stoian, Kalliopi Pafili, Khalid Al Rasadi, et al. "Experimental and Emerging Free Fatty Acid Receptor Agonists for the Treatment of Type 2 Diabetes." Medicina 58, no. 1 (January 11, 2022): 109. http://dx.doi.org/10.3390/medicina58010109.
Full textGrundmann, Manuel, Eckhard Bender, Jens Schamberger, and Frank Eitner. "Pharmacology of Free Fatty Acid Receptors and Their Allosteric Modulators." International Journal of Molecular Sciences 22, no. 4 (February 10, 2021): 1763. http://dx.doi.org/10.3390/ijms22041763.
Full textKaji, Izumi, Yasutada Akiba, Takafumi Furuyama, and Jonathan D. Kaunitz. "Sa1705 FFA3 Activation Inhibits Nicotine-induced Secretion and Motility via Enteric Nervous Reflex in Rat Proximal Colon." Gastroenterology 150, no. 4 (April 2016): S352. http://dx.doi.org/10.1016/s0016-5085(16)31234-3.
Full textKaji, Izumi, Yasutada Akiba, Kohtarou Konno, Masahiko Watanabe, Shunsuke Kimura, Toshihiko Iwanaga, Ayaka Kuri, Ken-ichi Iwamoto, Atsukazu Kuwahara, and Jonathan D. Kaunitz. "Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon." Journal of Physiology 594, no. 12 (March 20, 2016): 3339–52. http://dx.doi.org/10.1113/jp271441.
Full textSaid, Hyder, Yasutada Akiba, Kazuyuki Narimatsu, Koji Maruta, Ayaka Kuri, Ken-ichi Iwamoto, Atsukazu Kuwahara, and Jonathan D. Kaunitz. "FFA3 Activation Stimulates Duodenal Bicarbonate Secretion and Prevents NSAID-Induced Enteropathy via the GLP-2 Pathway in Rats." Digestive Diseases and Sciences 62, no. 8 (May 18, 2017): 1944–52. http://dx.doi.org/10.1007/s10620-017-4600-4.
Full textKaji, Izumi, Yuki Shimizu, Junki Miyamoto, Ikuo Kimura, and Jonathan D. Kaunitz. "Sa1214 - The Anti-Diarrheal Effect of Free Fatty Acid Receptor (Ffa)3 Agonist Ar420626 is Independent of Ffa3 or Pyy Signaling in a Murine Model of Irritable Bowel Syndrome." Gastroenterology 154, no. 6 (May 2018): S—279—S—280. http://dx.doi.org/10.1016/s0016-5085(18)31295-2.
Full textSaid, Hyder, Yasutada Akiba, Izumi Kaji, and Jonathan D. Kaunitz. "683 Selective FFA3 Agonists Stimulates Duodenal Bicarbonate Secretion and Prevents NSAID-Induced Enteropathy via the GLP-2 Pathway in Rats." Gastroenterology 150, no. 4 (April 2016): S141. http://dx.doi.org/10.1016/s0016-5085(16)30574-1.
Full textKimura, Ikuo, Atsuhiko Ichimura, Ryuji Ohue-Kitano, and Miki Igarashi. "Free Fatty Acid Receptors in Health and Disease." Physiological Reviews 100, no. 1 (January 1, 2020): 171–210. http://dx.doi.org/10.1152/physrev.00041.2018.
Full textWon, Y. J., V. B. Lu, H. L. Puhl, and S. R. Ikeda. "-Hydroxybutyrate Modulates N-Type Calcium Channels in Rat Sympathetic Neurons by Acting as an Agonist for the G-Protein-Coupled Receptor FFA3." Journal of Neuroscience 33, no. 49 (December 4, 2013): 19314–25. http://dx.doi.org/10.1523/jneurosci.3102-13.2013.
Full textKytikova, O. Yu, T. P. Novgorodtseva, Yu K. Denisenko, M. V. Antonyuk, and T. A. Gvozdenko. "Medium and long chain free fatty acid receptors in the pathophysiology of respiratory diseases." Bulletin Physiology and Pathology of Respiration, no. 80 (July 16, 2021): 115–28. http://dx.doi.org/10.36604/1998-5029-2021-80-115-128.
Full textIsobe, Junya, Shintarou Maeda, Yuuki Obata, Keito Iizuka, Yutaka Nakamura, Yumiko Fujimura, Tatsuki Kimizuka, et al. "Commensal-bacteria-derived butyrate promotes the T-cell-independent IgA response in the colon." International Immunology 32, no. 4 (December 20, 2019): 243–58. http://dx.doi.org/10.1093/intimm/dxz078.
Full textVelasco, Cristina, Marta Conde-Sieira, Sara Comesaña, Mauro Chivite, Adrián Díaz-Rúa, Jesús M. Míguez, and José L. Soengas. "The long-chain fatty acid receptors FFA1 and FFA4 are involved in food intake regulation in fish brain." Journal of Experimental Biology 223, no. 17 (July 14, 2020): jeb227330. http://dx.doi.org/10.1242/jeb.227330.
Full textChristiansen, Elisabeth, Kenneth R. Watterson, Claire J. Stocker, Elena Sokol, Laura Jenkins, Katharina Simon, Manuel Grundmann, et al. "Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases." British Journal of Nutrition 113, no. 11 (April 28, 2015): 1677–88. http://dx.doi.org/10.1017/s000711451500118x.
Full textHori, Yasushi, Kazutoshi Nakamura, Masaharu Yamamoto, Kenji Shimada, Hiroto Nakadaira, Norio Shibuya, Kazuo Endoh, and Kazuei Ogoshi. "Determination of Free Fatty Acids in Human Bile by High-Performance Liquid Chromatography." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 35, no. 2 (March 1998): 279–82. http://dx.doi.org/10.1177/000456329803500213.
Full textAlharbi, Abdulrahman G., Andrew B. Tobin, and Graeme Milligan. "How Arrestins and GRKs Regulate the Function of Long Chain Fatty Acid Receptors." International Journal of Molecular Sciences 23, no. 20 (October 13, 2022): 12237. http://dx.doi.org/10.3390/ijms232012237.
Full textPilitsis, Julie G., William M. Coplin, Michael H. O'Regan, Jody M. Wellwood, Fernando G. Diaz, Marilynn R. Fairfax, Daniel B. Michael, and John W. Phillis. "Free fatty acids in human cerebrospinal fluid following subarachnoid hemorrhage and their potential role in vasospasm: a preliminary observation." Journal of Neurosurgery 97, no. 2 (August 2002): 272–79. http://dx.doi.org/10.3171/jns.2002.97.2.0272.
Full textGormsen, L. C., N. Jessen, J. Gjedsted, S. Gjedde, H. Nørrelund, S. Lund, J. S. Christiansen, S. Nielsen, O. Schmitz, and N. Møller. "Dose-Response Effects of Free Fatty Acids on Glucose and Lipid Metabolism during Somatostatin Blockade of Growth Hormone and Insulin in Humans." Journal of Clinical Endocrinology & Metabolism 92, no. 5 (May 1, 2007): 1834–42. http://dx.doi.org/10.1210/jc.2006-2659.
Full textKaczmarek, Agata, and Mieczysława Irena Boguś. "The Impact of the Entomopathogenic Fungus Conidiobolus coronatus on the Free Fatty Acid Profile of the Flesh Fly Sarcophaga argyrostoma." Insects 12, no. 11 (October 27, 2021): 970. http://dx.doi.org/10.3390/insects12110970.
Full textPilz, Stefan, Hubert Scharnagl, Beate Tiran, Ursula Seelhorst, Britta Wellnitz, Bernhard O. Boehm, Jürgen R. Schaefer, and Winfried März. "Free Fatty Acids Are Independently Associated with All-Cause and Cardiovascular Mortality in Subjects with Coronary Artery Disease." Journal of Clinical Endocrinology & Metabolism 91, no. 7 (July 1, 2006): 2542–47. http://dx.doi.org/10.1210/jc.2006-0195.
Full textKojima, Kouji, Ui Matsumoto, Sumie Keta, Kenji Nakahigashi, Kazutaka Ikeda, Nobuyuki Takatani, Tatsuo Omata, and Makiko Aichi. "High-Light-Induced Stress Activates Lipid Deacylation at the Sn-2 Position in the Cyanobacterium Synechocystis Sp. PCC 6803." Plant and Cell Physiology 63, no. 1 (October 8, 2021): 82–91. http://dx.doi.org/10.1093/pcp/pcab147.
Full textJensen, Michael D., Sylvain Cardin, Dale Edgerton, and Alan Cherrington. "Splanchnic free fatty acid kinetics." American Journal of Physiology-Endocrinology and Metabolism 284, no. 6 (June 1, 2003): E1140—E1148. http://dx.doi.org/10.1152/ajpendo.00268.2002.
Full textPrihandoko, Rudi, Davinder Kaur, Coen H. Wiegman, Elisa Alvarez-Curto, Chantal Donovan, Latifa Chachi, Trond Ulven, et al. "Pathophysiological regulation of lung function by the free fatty acid receptor FFA4." Science Translational Medicine 12, no. 557 (August 19, 2020): eaaw9009. http://dx.doi.org/10.1126/scitranslmed.aaw9009.
Full textI. S. Sobczak, Amélie, Claudia A. Blindauer, and Alan J. Stewart. "Changes in Plasma Free Fatty Acids Associated with Type-2 Diabetes." Nutrients 11, no. 9 (August 28, 2019): 2022. http://dx.doi.org/10.3390/nu11092022.
Full textSørensen, Karina V., Mads H. Kaspersen, Jeppe H. Ekberg, Annette Bauer-Brandl, Trond Ulven, and Kurt Højlund. "Effects of Delayed-Release Olive Oil and Hydrolyzed Pine Nut Oil on Glucose Tolerance, Incretin Secretion and Appetite in Humans." Nutrients 13, no. 10 (September 27, 2021): 3407. http://dx.doi.org/10.3390/nu13103407.
Full textBollheimer, LC, DM Kemptner, SM Kagerbauer, TM Kestler, CE Wrede, and R. Buettner. "Intracellular depletion of insulin: a comparative study with palmitate, oleate and elaidate in INS-1 cells." European Journal of Endocrinology 148, no. 4 (April 1, 2003): 481–86. http://dx.doi.org/10.1530/eje.0.1480481.
Full textXu, Fangfang, Han Zhou, Xiumei Liu, Xiuli Zhang, Zhiwei Wang, Tao Hou, Jixia Wang, et al. "Label-free cell phenotypic study of FFA4 and FFA1 and discovery of novel agonists of FFA4 from natural products." RSC Advances 9, no. 26 (2019): 15073–83. http://dx.doi.org/10.1039/c9ra02142f.
Full textSeo, Woo-Keun, Juyeon Kim, Yoo Hwan Kim, Ji Hyun Kim, Kyungmi Oh, Seong-Beom Koh, and Hong Seok Seo. "Elevated Free Fatty Acid is Associated with Cardioembolic Stroke Subtype." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 38, no. 6 (November 2011): 874–79. http://dx.doi.org/10.1017/s0317167100012464.
Full textWang, Yu, Hui-Wen Zhang, Yuan-Lin Guo, Cheng-Gang Zhu, Na-Qiong Wu, and Jian-Jun Li. "Free fatty acids as a marker for predicting periprocedural myocardial injury after coronary intervention." Postgraduate Medical Journal 95, no. 1119 (January 2019): 18–22. http://dx.doi.org/10.1136/postgradmedj-2018-136137.
Full textXue, Yun, Ting Guo, Lifang Zou, Yingxin Gong, Bing Wu, Zhihua Yi, Tianyu Jia, et al. "Evodiamine Attenuates P2X7-Mediated Inflammatory Injury of Human Umbilical Vein Endothelial Cells Exposed to High Free Fatty Acids." Oxidative Medicine and Cellular Longevity 2018 (August 19, 2018): 1–10. http://dx.doi.org/10.1155/2018/5082817.
Full textHanuš, O., J. Vegricht, J. Frelich, A. Macek, M. Bjelka, F. Louda, and L. Janů. "Analysis of raw cow milk quality according to free fatty acid contents in the Czech Republic." Czech Journal of Animal Science 53, No. 1 (January 14, 2008): 17–30. http://dx.doi.org/10.17221/2717-cjas.
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