Relevant bibliographies by topics / Fetal brain Abnormalities

Academic literature on the topic 'Fetal brain Abnormalities'

Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "Fetal brain Abnormalities"

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Angtuaco, Teresita L. "Ultrasound Imaging of Fetal Brain Abnormalities." Ultrasound Quarterly 21, no. 4 (December 2005): 287–94. http://dx.doi.org/10.1097/01.wnq.0000186664.76284.da.

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Pfeifer, Cory M., Scott D. Willard, and Patricia Cornejo. "MRI depiction of fetal brain abnormalities." Acta Radiologica Open 8, no. 12 (December 2019): 205846011989498. http://dx.doi.org/10.1177/2058460119894987.

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Tao, Guowei, and David T. Yew. "Magnetic Resonance Imaging of Fetal Brain Abnormalities." Neuroembryology and Aging 5, no. 1-2 (2008): 49–55. http://dx.doi.org/10.1159/000116732.

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Stavljenic-Rukavina, Ana. "Molecular Genetics and Fetal Brain." Donald School Journal of Ultrasound in Obstetrics and Gynecology 2, no. 3 (2008): 87–99. http://dx.doi.org/10.5005/jp-journals-10009-1069.

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Abstract Molecular aspects of genetic diseases that affect the nervous system are in the focus of scientific interest investigators from many fields of medicine and the knowledge of genetic abnormalities as well as phenotypic heterogeneity is rapidly expanding. This review is aimed to provide clinician's practical insight into molecular aspects of certain brain abnormalities and disorders based on prenatal ultrasound assessment and clinical findings. Additionally some risk determinants are included in order to elucidate its contribution to molecular mechanism underlying the disease development. Making a specific diagnosis of a genetically determined neurological disorder or defects requires access to a laboratory that can assist in arranging for appropriate testing to be carried out. Therefore this review contains technological aspects of molecular genetic testing, international guidelines and policies related to genetic testing and recommendation for application in clinical medicine.
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Millichap, J. Gordon. "Continuum of Brain Abnormalities in Fetal Alcohol Syndrome." Pediatric Neurology Briefs 14, no. 5 (May 1, 2000): 35. http://dx.doi.org/10.15844/pedneurbriefs-14-5-4.

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Andersen, Stine Linding, Allan Carlé, Jesper Karmisholt, Inge Bülow Pedersen, and Stig Andersen. "MECHANISMS IN ENDOCRINOLOGY: Neurodevelopmental disorders in children born to mothers with thyroid dysfunction: evidence of fetal programming?" European Journal of Endocrinology 177, no. 1 (July 2017): R27—R36. http://dx.doi.org/10.1530/eje-16-0947.

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Fetal programming is a long-standing, but still evolving, concept that links exposures during pregnancy to the later development of disease in the offspring. A fetal programming effect has been considered within different endocrine axes and in relation to different maternal endocrine diseases. In this critical review, we describe and discuss the hypothesis of fetal programming by maternal thyroid dysfunction in the context of fetal brain development and neurodevelopmental disorders in the offspring. Thyroid hormones are important regulators of early brain development, and evidence from experimental and observational human studies have demonstrated structural and functional abnormalities in the brain caused by the lack or excess of thyroid hormone during fetal brain development. The hypothesis that such abnormalities introduced during early fetal brain development increase susceptibility for the later onset of neurodevelopmental disorders in the offspring is biologically plausible. However, epidemiological studies on the association between maternal thyroid dysfunction and long-term child outcomes are observational in design, and are challenged by important methodological aspects.
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Darbinian, Nune, Armine Darbinyan, John Sinard, Gabriel Tatevosian, Nana Merabova, Faith D’Amico, Tarek Khader, et al. "Molecular Markers in Maternal Blood Exosomes Allow Early Detection of Fetal Alcohol Spectrum Disorders." International Journal of Molecular Sciences 24, no. 1 (December 21, 2022): 135. http://dx.doi.org/10.3390/ijms24010135.

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Prenatal alcohol exposure can cause developmental abnormalities (fetal alcohol spectrum disorders; FASD), including small eyes, face and brain, and neurobehavioral deficits. These cannot be detected early in pregnancy with available imaging techniques. Early diagnosis could facilitate development of therapeutic interventions. Banked human fetal brains and eyes at 9–22 weeks’ gestation were paired with maternal blood samples, analyzed for morphometry, protein, and RNA expression, and apoptotic signaling. Alcohol (EtOH)-exposed (maternal self-report) fetuses were compared with unexposed controls matched for fetal age, sex, and maternal race. Fetal brain-derived exosomes (FB-E) were isolated from maternal blood and analyzed for protein, RNA, and apoptotic markers. EtOH use by mothers, assessed by self-report, was associated with reduced fetal eye diameter, brain size, and markers of synaptogenesis. Brain caspase-3 activity was increased. The reduction in eye and brain sizes were highly correlated with amount of EtOH intake and caspase-3 activity. Levels of several biomarkers in FB-E, most strikingly myelin basic protein (MBP; r > 0.9), correlated highly with morphological abnormalities. Reduction in FB-E MBP levels was highly correlated with EtOH exposure (p < 1.0 × 10−10). Although the morphological features of FAS appear long before they can be detected by live imaging, FB-E in the mother’s blood may contain markers, particularly MBP, that predict FASD.
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Stark, Zornitza, George McGillivray, Amanda Sampson, Ricardo Palma-Dias, Andrew Edwards, Joanne M. Said, Gillian Whiteley, and A. Michelle Fink. "Apert syndrome: temporal lobe abnormalities on fetal brain imaging." Prenatal Diagnosis 35, no. 2 (November 13, 2014): 179–82. http://dx.doi.org/10.1002/pd.4515.

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Akiyama, Shizuko, Neel Madan, George Graham, Osamu Samura, Rie Kitano, Hyuk Jin Yun, Alexa Craig, et al. "Regional brain development in fetuses with Dandy-Walker malformation: A volumetric fetal brain magnetic resonance imaging study." PLOS ONE 17, no. 2 (February 24, 2022): e0263535. http://dx.doi.org/10.1371/journal.pone.0263535.

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Dandy-Walker malformation (DWM) is a common prenatally diagnosed cerebellar malformation, characterized by cystic dilatation of the fourth ventricle, upward rotation of the hypoplastic vermis, and posterior fossa enlargement with torcular elevation. DWM is associated with a broad spectrum of neurodevelopmental abnormalities such as cognitive, motor, and behavioral impairments, which cannot be explained solely by cerebellar malformations. Notably, the pathogenesis of these symptoms remains poorly understood. This study investigated whether fetal structural developmental abnormalities in DWM extended beyond the posterior fossa to the cerebrum even in fetuses without apparent cerebral anomalies. Post-acquisition volumetric fetal magnetic resonance imaging (MRI) analysis was performed in 12 fetuses with DWM and 14 control fetuses. Growth trajectories of the volumes of the cortical plate, subcortical parenchyma, cerebellar hemispheres, and vermis between 18 and 33 weeks of gestation were compared. The median (interquartile range) gestational ages at the time of MRI were 22.4 (19.4–24.0) and 23.9 (20.6–29.2) weeks in the DWM and control groups, respectively (p = 0.269). Eight of the 12 fetuses with DWM presented with associated cerebral anomalies, including hydrocephalus (n = 3), cerebral ventriculomegaly (n = 3), and complete (n = 2) and partial (n = 2) agenesis of the corpus callosum (ACC); 7 presented with extracerebral abnormalities. Chromosomal abnormalities were detected by microarray analysis in 4 of 11 fetuses with DWM, using amniocentesis. Volumetric analysis revealed that the cortical plate was significantly larger in fetuses with DWM than in controls (p = 0.040). Even without ACC, the subcortical parenchyma, whole cerebrum, cerebellar hemispheres, and whole brain were significantly larger in fetuses with DWM (n = 8) than in controls (p = 0.004, 0.025, 0.033, and 0.026, respectively). In conclusion, volumetric fetal MRI analysis demonstrated that the development of DWM extends throughout the brain during the fetal period, even without apparent cerebral anomalies.
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Nagaraj, Usha D., and Beth M. Kline-Fath. "Clinical Applications of Fetal MRI in the Brain." Diagnostics 12, no. 3 (March 21, 2022): 764. http://dx.doi.org/10.3390/diagnostics12030764.

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Fetal magnetic resonance imaging (MRI) has become a widely used tool in clinical practice, providing increased accuracy in prenatal diagnoses of congenital abnormalities of the brain, allowing for more accurate prenatal counseling, optimization of perinatal management, and in some cases fetal intervention. In this article, a brief description of how fetal ultrasound (US) and fetal MRI are used in clinical practice will be followed by an overview of the most common reasons for referral for fetal MRI of the brain, including ventriculomegaly, absence of the cavum septi pellucidi (CSP) and posterior fossa anomalies.
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Dissertations / Theses on the topic "Fetal brain Abnormalities"

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Jarvis, Deborah. "Magnetic resonance imaging to enhance the diagnosis of fetal brain abnormalities in utero." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/19325/.

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Purpose This thesis aims to determine the diagnostic performance of in utero MR (iuMR) imaging to diagnose fetal brain abnormalities and describes the development, application and processing of a 3D volume MR acquisition. Methods A systematic review and meta-analysis of existing evidence was conducted. A prospective multicentre study of pregnant women, with a fetal brain abnormality on ultrasound (USS), was undertaken – The MERIDIAN study. In addition, an investigation of fetuses with no brain abnormality on USS was undertaken. Diagnostic accuracy and confidence, as well as positive and negative predictive values, were calculated. A 3D image acquisition technique was introduced, its ability to aid diagnosis measured and computational post-processing applied. Fetal brain volumes were extracted from the 3D data using image segmentation and these were assessed for reproducibility and validity. Resultant data allowed 3D models of fetal brains to be printed. Normally developing fetal brain volumes were plotted graphically thereby allowing comparison with abnormal fetuses. Results A total of 570 complete datasets were available from 903 eligible participants. Diagnostic accuracy was 68% for USS and 93% for iuMR. 95% of diagnoses made by iuMR were reported with high confidence compared to 82% on USS. Changes in pregnancy management occurred in 33% of cases. Positive and negative predictive values of iuMR were 93% and 99.5% respectively. 3D image quality was diagnostic in 89.6%, of which 91.4% gave an accurate diagnosis. Intra- and inter-observer agreement of brain volume measurements was high. Agreement between computer based and brain model volume measurements was also high. Conclusions iuMR imaging improves diagnostic accuracy and confidence for fetal brain abnormalities, influencing pregnancy management in a high proportion of cases. 3D imaging enables versatile visualisation of fetal brain anatomy and reliable extraction of volumes. This additional quantitative information could improve diagnosis in relevant cases.
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Books on the topic "Fetal brain Abnormalities"

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A, Chervenak Frank, Kurjak Asim, and Comstock C. H, eds. Ultrasound and the fetal brain. New York: Parthenon Pub. Group, 1995.

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Advanced obstetrical ultrasound: Fetal brain, spine, and limb abnormalities. Philadelphia, Pa: Saunders, 2008.

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Dev, Maulik, ed. Asphyxia and fetal brain damage. New York: Wiley-Liss, 1998.

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Maternal influences on fetal neurodevelopment: Clinical and research aspects. New York: Humana, 2010.

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1949-, Stevenson David K., ed. Fetal and neonatal brain injury. 4th ed. Cambridge: Cambridge University Press, 2009.

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1959-, Garel Cathérine, ed. MR imaging of the fetal brain: Normal development and cerebral pathologies. Berlin: Springer, 2004.

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Ruth, Vineta. Perinatal asphyxia: Biochemical parameters as indices of asphyxia at birth and predictors of brain damage, and a trial of preventing damage by phenobarbital. Helsinki: University of Helsinki, 1988.

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1942-, West James R., ed. Alcohol and brain development. New York: Oxford University Press, 1986.

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9

M, Donn Steven, Sinha, Sunil K., M.D., Ph.D., and Chiswick Malcolm L, eds. Birth asphyxia and the brain: Basic science and clinical implications. Armonk, N.Y: Futura Pub., 2002.

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G, Isaacson, and Lorber John, eds. Anomalies of the fetal head, neck, and spine: Ultrasound diagnosis and management. Philadelphia: Saunders, 1988.

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Book chapters on the topic "Fetal brain Abnormalities"

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Pooh, Ritsuko K. "Assessment of fetal brain abnormalities." In Clinical Maternal-Fetal Medicine Online, 52.1–52.12. 2nd ed. London: CRC Press, 2021. http://dx.doi.org/10.1201/9781003222590-47.

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Laurent, Guibaud. "Abnormalities of the Posterior Cerebral Fossa." In MRI of the Fetal Brain, 217–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18747-6_13.

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Garel, Catherine. "Abnormalities of Proliferation, Neuronal Migration and Cortical Organization." In MRI of the Fetal Brain, 151–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18747-6_10.

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Garel, Catherine. "Abnormalities of the Fetal Cerebral Parenchyma: Ischaemic and Haemorrhagic Lesions." In MRI of the Fetal Brain, 247–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18747-6_15.

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Malinger, Gustavo. "The Fetal Brain in Fetuses with Orofacial Abnormalities." In Prenatal Diagnosis of Orofacial Malformations, 131–41. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-32516-3_9.

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Vijayalakshmi, S., P. Durgadevi, S. P. Gayathri, and A. S. Mohammed Shariff. "Automated Fetal Brain Localization, Segmentation, and Abnormalities Detection Through Random Sample Consensus." In Data Science and Security, 495–504. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-2211-4_44.

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"Acquired Brain Abnormalities in Utero." In An Atlas of Fetal Central Nervous System Disease, 203–33. CRC Press, 2003. http://dx.doi.org/10.3109/9780203490679-14.

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Pooh, R., K. Maeda, and K. Pooh. "Acquired brain abnormalities in utero." In An Atlas of Fetal Central Nervous System Disease, 193–223. CRC Press, 2003. http://dx.doi.org/10.3109/9780203490679-8.

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"Fetal medicine and surgery." In Paediatric Surgery, edited by Mark Davenport and Paolo De Coppi, 73–102. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198798699.003.0003.

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This chapter begins by discussing fetal screening (screening for and diagnosis of chromosomal defects) and the use of magnetic resonance imaging in detecting problems such as brain abnormalities or congenital diaphragmatic hernia. Fetal diagnosis of cardiac anomalies, lung anomalies, congenital diaphragmatic hernia, abdominal wall defects, gastrointestinal anomalies, abdominal masses, obstructive uropathy, hydrocephalus, and spina bifida are discussed. There are probably two relevant surgical conditions where actual fetal intervention has a potential role. These are FETO fetoscopic endoluminal tracheal occlusion (FETO) for severe diaphragmatic hernia and in utero closure of spina bifida.
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Macnab, Andrew. "Pathogenesis and Prevention of Fetal and Neonatal Brain Injury." In Advancement and New Understanding in Brain Injury [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.93840.

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Recent advances in the clinical management of at-risk pregnancy and care of the newborn have reduced morbidity and mortality among sick neonates, and improved our knowledge of factors that influence the risks of brain injury. In parallel, the refinement of imaging techniques has added to the ability of clinicians to define the etiology, timing and location of pathologic changes with diagnostic and prognostic relevance to the developing fetus and newborn infant. Abnormalities of brain growth, or injury to the developing brain can occur during pregnancy; during labor and delivery, hypoxia, acidosis and ischemia pose major risks to the fetus. Defined practices for the management of pregnancy and delivery, and evidence-based strategies for care in the newborn period are influencing outcome. However, newborn infants, especially those born prematurely, remain at risk from situations that can cause or worsen brain injury. The literature reviewed here explains the mechanisms and timing of injury, and the importance of hypoxia, ischemia, hypotension and infection; describes current diagnostic strategies, neuroimaging technologies and care entities available; and outlines approaches that can be used to prevent or mitigate brain injury. Some show particular promise, and all are relevant to lowering the incidence and severity of brain damage.
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Conference papers on the topic "Fetal brain Abnormalities"

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Attallah, Omneya, Heba Gadelkarim, and Maha A. Sharkas. "Detecting and Classifying Fetal Brain Abnormalities Using Machine Learning Techniques." In 2018 17th IEEE International Conference on Machine Learning and Applications (ICMLA). IEEE, 2018. http://dx.doi.org/10.1109/icmla.2018.00223.

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Shinde, Kavita, and Anuradha Thakare. "Deep Hybrid Learning Method for Classification of Fetal Brain Abnormalities." In 2021 International Conference on Artificial Intelligence and Machine Vision (AIMV). IEEE, 2021. http://dx.doi.org/10.1109/aimv53313.2021.9670994.

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Shachina, M. Yu, A. S. Kharlamova, I. V. Barinova, A. E. Andreeva, A. E. Proshchina, and S. V. Saveliev. "Integrated сlinicopathologic diagnostics of the genetically determined human fetal brain abnormalities." In ЛУЧЕВАЯ ДИАГНОСТИКА ДЛЯ ПАТОЛОГИЧЕСКОЙ АНАТОМИИ И СУДЕБНО-МЕДИЦИНСКОЙ ЭКСПЕРТИЗЫ: ОТ ПРИЖИЗНЕННОЙ К ПОСМЕРТНОЙ. Москва: Межрегиональная общественная организация «Межрегиональное Танаторадиологическое Общество», 2022. http://dx.doi.org/10.54182/9785988117094_2022_46.

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Reports on the topic "Fetal brain Abnormalities"

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MRI scans help confirm ultrasound diagnosis of fetal brain abnormalities. National Institute for Health Research, April 2017. http://dx.doi.org/10.3310/signal-000404.

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