Dissertations / Theses on the topic 'Ferrocene'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Ferrocene.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Kedge, Jonathan L. "Synthesis of ferrocene nucleic acid monomers and ferrocene containing drug candidates." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7424/.
Full textKelly, Michael Jon. "Hybrid ferrocene-based systems." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:fd46594d-98d6-4f8a-a6ab-eb5ee74ba7f3.
Full textTazi, Mehdi. "Nouvelles fonctionnalisations de ferrocènes." Thesis, Rennes 1, 2019. http://www.theses.fr/2019REN1S124.
Full textThis thesis is mainly dedicated to the development of an original approach towards 1,3-disubstituted ferrocenes using the halogen ‘dance’ reaction. This reaction was first optimized on ferrocene carboxamide substrates. Although moderate yields were obtained, these are the first examples of controlled halogen ‘dance’ reaction in the ferrocene series. The noticed side-reactions allowed the key parameters for the success of the reaction to be identified. The halogen ‘dance’ reaction was next successfully developed in the fluoroferrocene series, an underexplored family of molecules with specific properties. Various trisubstituted ferrocenes were obtained and the reaction was also found able to deliver original tetrasubstituted ferrocenes and the very first example of hetero-pentasubstituted ferrocene. Finally, a preliminary electrochemical study was engaged. The determination of redox potentials of some of the original ferrocene derivatives allowed a better understanding of the substituent effects on ferrocene electronic behavior. Furthermore, it lays the ground for the development of an original purification process
Sachsinger, Niki. "Redox-active ligands containing ferrocene." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266646.
Full textSansook, Supojjanee. "Biological evaluation of ferrocene derivatives." Thesis, University of Sussex, 2017. http://sro.sussex.ac.uk/id/eprint/68599/.
Full textMirri, Giorgio. "Ferrocene-based electrochemical chiral sensors." Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/3140/.
Full textMagriñá, Lobato Ivan. "Development of electrochemical DNA sensors based on the incorporation ferrocene labelled dATP." Doctoral thesis, Universitat Rovira i Virgili, 2019. http://hdl.handle.net/10803/668964.
Full textEsta tesis doctoral está enfocada en el desarrollo de sensores electroquímicos de ADN, que són dispositivos analíticos descentralizados para la detección de secuencias de ADN. Este tipo de sensores tienen aplicaciones en muchas areas, incluyendo: el diagnóstico clínico, el control de enfermedades, el análisis de alimentos, la ciencia forense, el bioterrorismo i el control ambiental. Aun así, los sensores electroquímicos de ADN presentan problemas que aun tienen que ser resueltos, incluyendo la necesidad de amplificar la secuencia de ADN diana, la necesidad de generar ADN de cadena simple para una posterior hibridación con un ADN de captura complementario y finalmente el marcaje de este ADN hibridado para proceder con su detección. Esta tesis está enfocada en la eliminación de alguna de estas etapas para simplificar y mejorar los sensores electroquímicos de ADN existentes. Con tal de eliminar la etapa de marcaje de AD posteriora la hibridación hemos usado dATP modificado con ferroceno (dAEFcTP) durante la etapa de amplificación. Para eliminar la etapa de generación de ADN de cadena simple hemos utilizado dos estrategias distintas: el uso de “tailed primers” en lugar de primer convencionales, o alternativamente, la amplificación del ADN diana en fase sólida. Hemos comprobado que el dAEFcTP se incorpora adecuadamente en experiments de extensión de primer i hemos utilizado el dAEFcTP conjuntamente con tailed primers para desarrollar sensores electroquímicos para detectar los patógenos: K. armiger i B. anthracis. Además, hemos estudiado el electro que tiene el ratio dAEFcTP:dATP en el rendimiento de la amplificación, el pico de oxidación de ferrocene y el límite de detección del método.Además, tambinñen hemos estudiado cual es el efecto de la solución electrolyto de sorporrte en el pico de oxidaciñon del ferroceno. Finalmente hemos explorado el uso de dAEFcTP en conjuncuión con el método isotérmico de amplificación de ADN: recombinsae polymerase amplification
This thesis is focused on the development of electrochemical DNA sensors, which are decentralized analytical devices for use at the point-of-need for the detection of DNA sequences. These sensors can find widespread application in a number of diverse areas, including clinical diagnostics, disease monitoring, food analysis, forensics, bioterrorism and environmental control. However, electrochemical DNA sensors still have a number of problems that need to be addressed, including a need for the amplification of the target sequence, the need for post-amplification generation of single stranded DNA, target hybridization with a complementary capture probe and finally further reporting steps to detect the hybridized target DNA sequence. In this thesis we focused on the elimination of some of these steps to bring electrochemical DNA sensors closer to the point-of-need. To eliminate the reporting step we used ferrocene labelled dATP (dAEFcTP) to obtain already labelled target amplicons. To eliminate the single stranded generation step we followed two different strategies, the use of tailed primers instead of regular primers, or, alternatively performing DNA amplification directly on the electrode surface. The incorporation of dAEFcTP has been demonstrated in primer extension and amplification experiments. dAEFcTP and tailed primers have been used to develop a singleplex electrochemical sensor to detect K. armiger in seawater samples, and a duplex electrochemical sensor to detect B. anthracis in real samples. The effect of the dAEFcTP:dATP ratio on DNA amplification yield, ferrocene peak intensity and limit of detection has been studied, as well as the effect of the electrolyte solution on the ferrocene peak intensity. Finally, the use of dAEFcTP in combination with isothermal recombinase polymerase amplification was explored.
Soares, Daniel da Costa e. Silva Coelho. "Estudo estrutural de produtos da degradação de [Pd2(C2,N-(dmpa)2(μ-dppf)Cl2]." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/75/75132/tde-17042012-114913/.
Full textX-ray diffraction is a highly interdisciplinary science, whose development has enabled the advancement of several other scientific areas. The determination of three-dimensional structures of substances, whether natural or synthetic, have been fundamental to the study and understanding of the relationships between physical, chemical, therapeutic and structure at the atomic level. This work will present some theoretical aspects of ferrocene complexes and the theory involved in determining of molecular and crystal structures by XRD, as well as resolution and characterization of two ferrocene complexes. The results were compared with similar structures found in the Cambridge Structural Database. At the compounds studied in the present work, 1,1\'-bis(diphenylphosphine)ferrocene e {(Dichloride)[bis (diphenylphosphine)-ferrocene]Palladium(II)}oCHCl3, the Fe complexes with two cyclopentadyenil rings, at star conformation, which are disposed equidistant from Fe atom, without significant distortions. Due to the elevated toxicity of cis-platine at neoplasms, many research groups have been dedicated efforts to found compatible analog drugs, which the palladium derivatives are the most researched, because of their electronic and structural properties. It has been known that the geometry around the Pt is square planar, as like as the present case, which makes the {(Dichloride)[bis (diphenylphosphine)-ferrocene] Palladium(II)}oCHCl3, possible to be study at his possibly activity. One of the great unknowns in the area of pharmacology is to know exactly which are the products of degradation of a certain drug and determining by XRD the crystal and molecular structures of both studied compounds, concluded that they are derived from the degradation of the compound [Pd2(C2, N-(dmpa) 2 (μ-dppf)Cl2], since such compounds has their structures determined from a tube containing the [Pd2(C2, N-(dmpa) 2 (μ-dppf)Cl2]. So, the present work has considerable importance in the study of this drug which can be used against cancer.
Appel, Markus Andreas [Verfasser], Bernd Akademischer Betreuer] Stühn, and Michael [Akademischer Betreuer] [Vogel. "Ring Rotation in Ferrocene and Ferrocene-containing Polymers / Markus Andreas Appel. Betreuer: Bernd Stühn ; Michael Vogel." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2015. http://nbn-resolving.de/urn:nbn:de:tuda-tuprints-42268.
Full textAppel, Markus Andreas Verfasser], Bernd [Akademischer Betreuer] Stühn, and Michael [Akademischer Betreuer] [Vogel. "Ring Rotation in Ferrocene and Ferrocene-containing Polymers / Markus Andreas Appel. Betreuer: Bernd Stühn ; Michael Vogel." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2015. http://d-nb.info/1111112037/34.
Full textRosol, Malgorzata. "Síntesis y estudio de nuevos derivados ciclometalados del ferroceno / Synthesis and study of new cyclometallated derivatives of ferrocene." Doctoral thesis, Universitat de Barcelona, 2007. http://hdl.handle.net/10803/2799.
Full text1. The methodology designed for the synthesis of enantiomerically pure phosphane-substituted carbonyl complexes of propargyl aldehyde was not successful. The steric hindrance at position C-4 of the oxazolidin-2-one and oxazolidin-2-thione appears to difficult the removal of the auxiliary in the corresponding N-(2-alkynoyl) dicobaltcarbonyl complexes.
2. The general catalytic behavior of octacarbonyl dicobalt in the opening of cyclic ethers, such as tetrahydrofuran, by acid chlorides, leading to 4-chlorobutyl esters, has been demonstrated.
3. A pathway to access 1'-substituted and 2-substituted beta-ferrocenyl beta-amino alcohols has been developed. In this way, the synthesis with a high level of enantiomeric purity of (S)-2-amino-2-(1'-methyl)ferrocenylethanol, (pS,R)-2-amino-2-(1-trimethylsilyl)-ferrocenyl ethanol and (pR,R)-2-amino-2-(1-methyl) ferrocenyl ethanol has been achieved via their corresponding diols.
4. A general methodology which gives easy access to mono and disubstituted (1,1'- and 1,2-) 4-ferrocenyl-1,3-oxazolines has been developed.
5. A new type of interannular cyclopalladation of ferrocene has been established. The reaction seems to be quite general for 4-ferrocenyl-1,3-oxazolines with different degrees of substitution of the ferrocene moiety, provided that the C2-oxazoline substituent bears no á-hydrogens. The reaction of 4-ferrocenyl-1,3-oxazolines with palladium acetate in benzene leads to the formation of C2-symmetric complexes with two ferrocene moieties cycloplalladated at the 1' position, connected by a central palladium and four acetate bridges. When the cyclopalladation is performed by disodium tetrachloropalladate, a similar complex, but with two chloride bridges, is obtained. The 3-palladium acetate complexes can be converted into the 2-palladium chloride ones by treatment with lithium chloride in methanol. The structures of both types of complexes have been thoroughly studied by spectroscopy and by X-ray diffraction.
6. Cyclic voltammetric studies of these novel interannular palladacycles have been performed.
7. The µ-chloro bridged dipalladium complex (S)-84 undergoes bridge-splitting with triphenylphosphine leading in nearly quantitative yield to the monomer complex (S)-95. On the other hand, the reaction of (S)-84 with iodine affords 1'-iodo-2-tert-butyl-4-ferrocenyl oxazoline (S)-100. This compound has been converted into 1'-phenyl-2-tert-butyl-4-ferrocenyloxazoline (S)-101 by Suzuki coupling with phenylboronic acid. Finally, (S)-84 leads in good yields to the 1'-diphenylphosphinyl- and 1'-diphenylphosphinothioyl ferrocenes (S)-103 and (S)-104.
8. Interannularly palladated 4-ferrocenyl-1,3-oxazolines behave as active promoters of the Heck olefination, allowing the reaction to be performed at lower temperatures than previously known CN-palladacycle pre-catalysts derived from ferrocene. In the reaction medium, the olefin partner couples with the 1'-position of the ferrocene, leading to the formation of soluble palladium(0) catalytic species. For the first time, the ligand-olefin adduct has been isolated and unequivocally characterized, and further evidence favoring the involvement of a Pd(0)/Pd(II) catalytic cycle has been obtained.
9. The new interannular cyclopalladated ferrocenes have been found to be good catalysts for the asymmetric aza-Claisen rearrangement. Thus, the rearrangement of (E)-cinnamyl N-aryl benzimidates 129-131 takes place with moderate yields (40-49%) and with excellent enantioselectivity (up to 90% ee of the rearranged amide 138). Interestingly enough, the acetate-bridged 3Pd complexes lead to the (S) enantiomer of the rearranged allylic amide, while the chloride bridged 2Pd complexes (from the same (S)-enantiomer of the chiral 4-ferrocenyl-1,3-oxazoline) lead to the opposite (R) enantiomer of the amide.
10. New and outstanding catalysts for the aza-Claisen rearrangement of (E)- and (Z)-allylic trichloroacetimidates have been found. The rearrangement of both (E)- and (Z)-hexenyl trichloroacetimidates, performed in chloroform solution at 38oC with a molar 5% of the chloride bridged 1'-cyclopalladated complex, takes place with quantitative conversion and with outstanding enantioselectivity (>98% ee), according to 1H-NMR and HPLC analyses. Intriguingly, both diastereomers of the starting imidate lead to the same enantiomer (S) of the rearranged amide 142.
Velioglu, Ozlem. "Synthesis Of Ferrocenyl Substituted Quinolines." Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/3/12609785/index.pdf.
Full textOnyancha, Douglas Okerio. "Synthesis, characterization and reactions of novel ferrocenylimidazoles as donor ligands." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1150.
Full textCho, Yongjin. "Chiral ferrocene ligands for asymmetric cross coupling." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300034.
Full textHumphries, Kristina. "Synthesis and reactivity of chiral ferrocene complexes." Thesis, Keele University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265643.
Full textBroomsgrove, Alexander Edward John. "Ferrocene based Lewis acids for anion sensing." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:bfab3690-f1de-4c8d-b111-ce9083710b16.
Full textMalone, Johnathan Scott. "Magnetic Characterization of Ferrocene Derived Carbon Nanotubes." OpenSIUC, 2014. https://opensiuc.lib.siu.edu/theses/1582.
Full textAndrade, Gustavo Fernandes Souza. "Caracterização espectroscópica da tiossemicarbazona do formilferroceno (TFF) através das técnicas SERS (Surface-Enhanced Raman Scattering) e Raman ressonante." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/46/46132/tde-13092006-164920/.
Full textIn this dissertation, the adsorption process of the formylpyridine thiosemicarbazone (TFF) at silver and gold surfaces in aqueous and in acetonitrile solutions has been characterized by using the SERS (Surface-enhanced Raman Scattering) technique. It has been verified that TFF adsorbs through N1 and S atoms on the metallic surfaces. The faradaic processes of TFF have been monitored through the SERS and UV-visible absorption spectroscopies. The SERS spectra at -1,4 V (Ag/AgCl) suggest aminomethylferrocene as one of the reduction products of TFF. By using the UV-visible absorption technique, it has been verified, at this potential, a new band at 240 nm in the spectrum, which indicates the presence of thiourea. The observation of these two reduction products has confirmed that the general reduction mechanism for thiosemicarbazonas works for TFF. Neither SERS nor UV-vis spectral changes have been observed during the redox process of FeII/FeIII (E1/2= 0,55 V). The adsorption and faradaic processes of thisemicarbazide (TSC) at silver electrode have also been studied by SERS technique. It has been verified that, in acidic and neutral media, the TSC is adsorbed through a cis-configuration at a potential close to 0,0 V, showing an interaction of the S atom through bond formation with the surface and through the H atoms bonded to N1 via ion pair formation with the adsorbed Cl- anions. At more negative potentials, the chloride anions leave the electrode surface and the TSC changes to trans-configuration. No faradaic process has been observed as reported in the literature. This result has been confirmed by using the capillary electrophoresis technique. The resonance Raman effect of the TFF has been studied, and the excitation profiles of the bands have been shown as minimum, which indicates an electronic interaction between the two cromophores of the TFF (thiosemicarbazone and ferrocenyl). The theoretic excitation profiles have been calculated by using the transform method, and the results of the obtained adjustment has indicated that there has been a distortion of the ferrocenyl vibrational modes for an electronic transition at 312 nm, assigned to the n-p* of thiosemicarbazone moiety. This result has indicated a great interaction between the two cromophores of TFF. In order to compare the resonance Raman behavior of the TFF with that of the ferrocene, the resonance Raman spectra of the ferrocene have been obtained. It has been verified that the two compounds present an anti-resonant Raman effect, even though the bands have presented very different excitation profiles from those observed in the TFF, which indicates that the incorporation of the thiosemicarbazone group into the ciclopentadienyl has changed the electronic structure of the ferrocenyl group.
Fern, Glen Matthew. "Ferrocenes of Substituted Indenyl Ligands." Thesis, University of Canterbury. Chemistry, 2005. http://hdl.handle.net/10092/1266.
Full textKelly, Glenn Anthony. "Synthetic studies of ferrocene-containing monomers and polymers." Thesis, Bangor University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273670.
Full textMaharjan, Bidhya L. "FERROCENE-FUSED DERIVATIVES OF ACENES, TROPONES AND THIEPINS." UKnowledge, 2015. http://uknowledge.uky.edu/chemistry_etds/53.
Full textHoffmann, Viktor [Verfasser]. "Ferrocene as Functional Subunits in Macrocycles / Viktor Hoffmann." München : Verlag Dr. Hut, 2017. http://d-nb.info/1139538497/34.
Full textWinder, Robert John. "The synthesis of some ferrocene substituted porphyrinic macrocycles." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315068.
Full textRoberts, Holly Victoria. "Ferrocene conjugated DNA for biosensing and antisense applications." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8663/.
Full textTakase, Masayoshi. "Molecular Recognition Abilities of Ferrocene-Modified Multitopic Receptors." 京都大学 (Kyoto University), 2003. http://hdl.handle.net/2433/149097.
Full textHopkins, Peter K. "Novel tripodal ligands designed to complex anions." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249200.
Full textZehnder, Ralph. "Polynuclear metallocene complexes incorporating ansa-chromocene and ferrocene units." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=96652683X.
Full textResendes, Rui. "Ring-opened poly(ferrocene)s, new directions and applications." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0015/NQ53681.pdf.
Full textNeidlinger, Andreas [Verfasser]. "Ferrocene-phenol conjugates – secondary structures and reactivity / Andreas Neidlinger." Mainz : Universitätsbibliothek Mainz, 2017. http://d-nb.info/1126763152/34.
Full textAllison, Matthew Steven. "Heterobimetallic ruthenium complexes containing ferrocene as anti-cancer agents." Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/20629/.
Full textMulas, Andrea. "Ferrocene-based chiral monomers and oligomers for sensing applications." Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/4154/.
Full textBoissonnet, Michel-Franck. "Hydrogen-bonding ferrocene derivatives for molecular recognition and organocatalysis." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/6121/.
Full textHerbert, Simon Anthony. "Oxazoline directed lithiation of Calix[4]arene and Ferrocene." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/17867.
Full textENGLISH ABSTRACT: The use of chiral oxazoline directed lithiation provides a highly diastereoselective (up to >99% de) route to meta functionalised inherently chiral calixarenes. This methodology can be used on both the butylated and debutylated calixarene systems and is tolerant of a wide range of different electrophillic quenches allowing access to a structurally diverse range of inherently chiral metafunctionalised calixarenes. The oxazoline directing group can be removed via hydrolysis, generating a range of functionalised calixarene carboxylic acids in high ee. We also demonstrate that the use of derivative alkyllithiums such as cyclopentyl lithium can provide significantly enhanced diastereoselectivity over the conventional organolithiums such as sec-butyl lithium, when employed in ortholithiation reactions of this nature. The differences in diastereoselectivity associated with the different alkyllithiums can be tied, in certain cases, to the steric bulkiness associated with the individual reagents. In this regard we have found that the use of the so called Tolman angle or cone angle approach allows quantification of the relative steric bulk of the alkyllithium. We also detail that the oxazoline directing group provides a hitherto unknown ability to be diastereoselectively tuned through the choice of the ligand system in the ortholithiation reaction. In this regard the development of a series of diglyme based ligands have proved to provide a highly diastereoselective means of inverting the chirality from that which the use of the conventional TMEDA ligand is able to generate (up to –92% de). The use of diglyme ligands to invert the sense of chirality is also shown to occur on the ferrocenyloxazoline system and presents an apparently general and hitherto unknown facet of asymmetric oxazoline directed ortholithiation. This diglyme induced inversion has been shown to be controlled through a secondary nitrogen coordinated mechanism that is able to operate with chiral oxazolines.
AFRIKAANSE OPSOMMING: Die gebruik van chirale oksasoliengerigte litiëring verskaf ’n hoogs diastereoselektiewe (tot en met >99% do) roete om metagefunksionaliseerde, inherente chirale calixareen produkte te sintetiseer. Deur gebruik te maak van verskillende elektrofiele kan die metodologie toegepas word op beide gebutileerde en de-gebutileerde calixareen sisteme om ’n reeks uiteenlopende inherente chirale, meta-gefunksionaliseerde calixareen produkte te vorm. Die oksasolien groep kan daarna verwyder word deur hidroliese om ’n reeks gefunksionaliseerde calixareenkarboksielsure te vorm in baie hoë eo. Ons het ook gedemonstreer dat die gebruik van afgeleide alkiel-litiums, soos siklopentiel-litium, kan bydrae tot aansienlik verhoogde diastereoselektiwiteit as dit vergelyk word met meer algemene organolitiums soos sekbutiellitium, tydens ortolitiëring reaksies van hierdie natuur. Die verskille in diastereoselektiwiteit kan verbind word, in sekere gevalle, tot die steriese bonkigheid van die individuele reagense. Deur gebruik te maak van die sogenaamde Tolmanhoeke of die koniesehoek benadering is dit moontlik om die relatiewe steriese bonkighied van alkiellitiums te kwantifiseer. Daar was ook bepaal dat die oksasoliengroep die ongekende vermoë besit om die diastereoselektiwiteit van die produk te stem deur die keuse van verskillende ligand sisteme tydens die ortolitiëring reaksie. Daar was bepaal dat die chiralitiet van die produkte omgekeer kan word op ’n hoogs diastereoselektiewe manier, deur gebruik te maak van ’n reeks ontwikkelde diglymegebaseerde ligande, indien dit vergelyk word met die produkte wat deur die konvensionele TMEDA gegenereer was (tot en met –92% do). Die gebruik van diglyme ligande was ook getoets op ferroseenoksasolien sisteme en dit was bevind dat dieselfde omkering in chiraliteit ook plaasvind wat aanleiding kan gee tot 'n oënskynlik algemene en tot nou toe onbekende faset van asimmetriese oksasoliengerigte orto-litiëring. Dit is bepaal dat hierdie diglyme geïnduseerde omkering in chiraliteit beheer word deur middel van 'n sekondêre stikstofgekoördineerde meganisme, wat in staat is om saam te werk met chirale oksasoliene.
Caniparoli, Ulysse. "Ferrocene-Based Chiral Catalyst Design for Enantioselective Cycloadditions Reactions." Doctoral thesis, Universitat Rovira i Virgili, 2021. http://hdl.handle.net/10803/672970.
Full textLa presente tesis describe el diseño y la síntesis de una nueva clase de ligandos basados en ferroceno, y su aplicación en catálisis enantioselectiva con Au(I). Estos ligandos han sido específicamente implementados para superar las dificultades de la catálisis enantioselectiva con Au(I) debido a la separación espacial entre la información quiral en el ligando y el centro activo localizado en la cara opuesta del metal. Se ha desarrollado una síntesis modular de 1-(2’-dialquilarilfosfina)-3-arilferroceno, permitiendo el acceso a una familia de complejos quirales de Au(I) con diferentes propiedades estéricas y electrónicas. Se identificó un complejo quiral de Au(I) como catalizador para la cicloadición [4+2] formal de 1,6-arileninos con elevados rendimientos y buenas enantioselectividades. El modo de acción de nuestro catalizador quiral se ha estudiado computacionalmente, encontrándose que una interacción atractiva no covalente entre el ligando y el sustrato es crucial para lograr una elevada inducción enantiomérica. Asimismo, hemos aplicado un complejo de Au(I), cuyo ligando fosfina incluye una pirrolidina quiral 2,5-disustituida con simetría C2 en posición remota, a la síntesis de ferrocenos con quiralidad planar mediante una reacción de hidroarilación de (2-alquinilaril)ferrocenos.
This thesis describes the design and synthesis of a new class of ferrocene-based ligands applied to enantioselective gold(I) catalysis. These ligands have been specifically implemented to overcome difficulties of enantioselective gold(I) catalysis due to the spatial separation between the chiral information on the ligand and the catalytic site located on the opposite side of the metal center. A modular synthesis of 1-(2’-dialkylarylphosphine)-3-arylferrocene was developed allowing to access a family of chiral gold(I) complexes bearing various steric and electronic properties. One chiral gold(I) complex was identified to catalyze the formal [4+2] cycloaddition of 1,6-arylenynes in high yields and good enantioselectivities. The working mode of our chiral catalysts was studied computationally. An attractive non-covalent interaction between the ligand and the substrate was found to be crucial to achieve high enantioinduction. Additionally, we applied a phosphine-supported gold(I) complex containing a chiral remote C2-symmetric 2,5-disubstituted pyrrolidines to the enantioselective synthesis of planar chiral ferrocenes by hydroarylation of (2-alkynylaryl)ferrocenes.
MALEZIEUX, BERNARD. "Chiralite plane en chimie du ferrocene et du benchrotrene." Paris 6, 1995. http://www.theses.fr/1995PA066152.
Full textWang, Lixin. "Ferrocene-based molecular electronics and nanomanufacturing of palladium nanowires." College Park, Md. : University of Maryland, 2007. http://hdl.handle.net/1903/7757.
Full textThesis research directed by: Dept. of Chemistry and Biochemistry. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
Magnani, Maurizio. "Polimeri metacrilici contenenti ferrocene: sintesi mediante ATRP e proprietà." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/6545/.
Full textBeskeni, Rhoda. "Synthesis of staggered triphenylene twins linked through ferrocene bridges." Thesis, University of East Anglia, 2016. https://ueaeprints.uea.ac.uk/63359/.
Full textHalstead, Joshua M. "Oxidation of Ferrocene Derivatives with Dibenzoyl Peroxide and meta-Chloroperoxybenzoic Acid." Cleveland State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=csu154278958361703.
Full textGupta, Deepshikha. "NEW APPROACHES TO CYCLOPENTADIENYL-FUSED THIOPHENE COMPLEXES OF IRON and SYNTHESIS AND CHARACTERIZATION OF CARBONIC ANHYDRASE ACTIVE-SITE MIMICS FOR CO2 HYDRATION." UKnowledge, 2018. https://uknowledge.uky.edu/chemistry_etds/92.
Full textRatera, Bastardas Imma. "Ferrocene-Based Polychlorotriphenylmethyl radical: A new approach towards multiproperty materials." Doctoral thesis, Universitat Autònoma de Barcelona, 2002. http://hdl.handle.net/10803/3149.
Full textS'han estudiat les propietats magnètiques dels diferents mono- bi- i tri- radicals mitjançant les tècniques d'EPR i SQUID. A partir de les dades obtingudes pels biradicals estudiats, es pot concloure que el pont 1,1'-ferrocenilè actua com a acoblador ferromagnètic entre les dues unitats radicalàries connectades a ell. Quan el ferrocè és substituït amb grups metílics o bé és substituït per un rutenocè, l'acoblament magnètic entre les dues unitats radicalàries desapareix mostrant-se un comportament paramagnètic al llarg de tot el rang de temperatures mesurat. A partir de les dades de susceptibilitat magnètica dels monoradicals s'obtenen valors de magnetització molt alts a temperatura ambient els quals són un indici de la significant contribució orbitàlica de la fracció de Fe (III) per sobre del valor del spin orgànic sol. Aquest resultat suggereix un fenomen de transferència electrònica intramolecular entre el ferrocè i la unitat radicalària. A més a més, per un dels monoradicals sintetitzats, també se n'ha estudiat la isomerització trans - cis tant tèrmica com fotoinduïda mitjançant la tècnica de UV/Vis, ESR spectrosocopy així com també de cromatografia d'HPLC. Aquesta isomerització genera un procés d'autoassemblatge induït tan tèrmica- com fotoquímicament d'un sol sentit i representa un exemple molt interessant d'un sistema fotomagnètic basat en un fenomen supramolecular en el qual una espècie doblet es convertida a una espècie singlet.
Aquesta família de radicals policlorotrifenilmetílics units a un ferrocè també presenten un fenomen de transferència electrònica intramolecular del qual se'n pot modular la seva energia fàcilment mitjançant el canvi de substituents de la unitat donadora, acceptora o fins i tot canviant la naturalesa del dissolvent. Mesures d'absorció espectroscòpiques de temps de resolució de pico-segons ens han permès observar i monitoritzar per primera vegada l'espècie de càrregues separades la qual ens confirma per primera vegada el fenomen de transferència electrònica intramolecular fotoinduït. També ha estat descrit per primera vegada un nou exemple de tautomerisme de valència que combina un radical orgànic com a grup acceptor i un ferrocè com a grup donador.
Finalment, també s'ha comprovat que els radicals policlorotrifenilmetílics constitueixen un sèrie de compostos de capa electrònica oberta molt atractiva que combina elevades respostes d'ONL amb bones estabilitats químiques, tèrmiques i foto-òptiques, gràcies al seu caràcter octupolar. Els sistemes de ferrocens connectats a unitats radicalàries policlorotrifenilmetíliques també exhibeixen intenses respostes d'ONL les quals poden ser modulades mitjançant el canvi de capacitat donadora del metal.locè o accpetora del radical.
This thesis as part of a general effort aimed at extending the range of molecular materials combining two properties in the same molecule, has developed the synthesis and characterization of new series of metallocene (ferrocene and ruthenocene) based polychlorotriphenylmethyl mono, bi- and tri- radicals proving that it is possible their tuning by changing the donor ability of the metallocene unit, the acceptor ability of the radical unit and the nature of the bridge. The magnetic properties of different mono, bi and tri radicals have been studied by EPR and SQUID. From the magnetic data of the biradicals studied, it is conclude that the 1,1'-ferrocenylene bridge acts as a ferromagnetic coupler between the two radical units connected to it. When the ferrocene unit is substitute with methyl groups or it is changed for a ruthenocene unit, the magnetic exchange vanishes showing a paramagnetic behaviour in all the temperature range. From the magnetic susceptibility data for the monoradicals an outsized values of magnetization at room temperature is observed, which it is an indication of significant orbital contributions of the Fe(III) fraction over the spin value. This result suggests a temperature dependent intramolecular electron transfer phenomenon between the ferrocene and the radical unit. In addition, the thermal and photoinduced trans to cis isomerization of one of the monoradicals has been monitored by UV/Vis and ESR spectrosocopy and also followed by HPLC chromatography. This one-way thermal and photoinduced self-assembly process represents an interesting example of a photomagnetic system based on a supramolecular phenomenon in which a doublet species is converted into a singlet one.
Such ferrocene-polychlorotriphenylmethyl radicals present intramolecular electron transfer phenomenon which energy can be easily tuned by changing the substitutents of the donor or acceptor units or even the nature of the solvent. Picosecond time resolved absorption spectroscopy measurements allow us observing and monitoring for the first time the charge separation state that confirms the photoinduced electron transfer phenomena. It has also been described for the first time a novel valence tautomeric example combining an organic radical as acceptor unit and a ferrocene unit as the donor group.
Finally, it has been proved that polychlorotriphenylmethyl radicals constitute a very attractive open-shell series that combines both a high NLO response and good chemical, thermal, and photo-optical stabilities, thanks to their octupolar character. Ferrocene based polychlorotriphenylmethyl radicals systems also exhibits intense NLO responses that can be modulated at will simply tuning the donor and acceptor capabilities of the ferrocene and radical units.
Lenze, Norman. "Neuartige Zinn- und Gallium-substituierte Ferrocene Synthese, Struktur und Eigenschaften /." [S.l. : s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=969324057.
Full textElihn, Karine. "Synthesis of carbon-covered iron nanoparticles by photolysis of ferrocene." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5302-3/.
Full textDu, Shuoren. "Towards redox control of organometallic catalysts bearing ferrocene-based ligands." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/23902.
Full textKrauße, Nico [Verfasser]. "Ausgedehnte [pi]-Systeme auf Basis 1,1'-disubstituierter Ferrocene / Nico Krauße." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover (TIB), 2014. http://d-nb.info/1049227972/34.
Full textAl, Khalyfeh Khaled. "Ferrocene-Based Monomers, Oligomers and Polymers as Electro-Active Materials." Doctoral thesis, Universitätsbibliothek Chemnitz, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-216647.
Full textDie vorliegende Doktorarbeit beschäftigt sich mit Synthese und Charakterisierung von funktionalisierten Ferrocenen mit bis zu vier Aldehyd- und Vinylgruppen und ihrer Verwendung als Monomere für neuartige ferrocenbasierte Oligomere mit konjugiertem Rückgrat unter ADMET (acyclic diene metathesis) und HWE- (Horner-Wadsworth-Emmons) Reaktionsbedingungen. Zusätzlich wurden ferrocenhaltige Polymere mit einem aliphatischen Rückgrat durch Polymerisation mit und ohne Lösemittel hergestellt und ihr elektrochemisches Verhalten untersucht. Das Hauptaugenmerk dieser Arbeit liegt in der Optimierung der elektrochemischen Eigenschaften der ferrocenbasierten Materialien (Oligomere oder Polymere) durch Variation des Polymerrückgrats, welche zahlreiche funktionelle Gruppen für die vernetzte Polymerisation und die Co-Polymerisation liefert. Durch diesen Prozess wird das molekulare Gewicht erhöht. Zusätzlich wird die Verwendung als elektroaktive Materialien insbesondere für die Energiespeichertechnik diskutiert. Durch lösungsmittelfreie Reaktionsbedingungen wurden ein hoher Monomerumsatz, relativ hohe molare Massen und zugleich längere Polymerketten erzielt. Elektrochemische Messungen (CV) zeigten, dass Ferrocenmoleküle mit mehr als zwei Formylgruppen die Elektronendichte an der Ferrocenyleinheit verringern und bei Oxidation leicht zersetzt werden. Erniedrigung der Messtemperatur und die Verwendung des nur schwach koordinierenden Leitsalzes [NnBu4][B(C6F5)4] führten zu aussagekräftigen Ergebnissen. Weiterhin konnte ein linearer Zusammenhang zwischen dem Redoxpotential und der Anzahl der Formyleinheiten aufgezeigt werden. Mutlizyklische Messungen bestätigten, dass das Ferrocen / Ferrocenium-Redoxpaar mindestens 100 Zyklen stabil ist. Mittels spektroelectrochemisches Messungen konnte gezeigt werden, dass konjungierte (oligomere) Verbindungen eine elektronische Wechselwirkung (IVCT) aufweisen, während aliphatische Rückgrade eine Wechselwirkung zwischen Ferrocen / Ferrocenium (polyvinylferrocenbasierte Materialien) verhindern und nur ein LMCT Übergang (Ligand zu Metall Charge-Transfer) beobachtet werden kann
Frison, Gilles. "Du phosphinidene au ferrocene : un dialogue entre experience et theorie." Paris 6, 2000. http://www.theses.fr/2000PA066175.
Full textEralp, Tugce. "Synthesis Of Ferrocenyl Quinones And Polyquinanes." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/3/12606205/index.pdf.
Full texte M.S., Department of Chemistry Supervisor: Assoc. Prof. Dr. Metin Zora June 2005, 79 pages With the discovery of antitumor activity of ferrocene derivatives, research on new ferrocene derivatives have gained importance. For this purpose, we have investigated the synthesis of ferrocenyl quinones starting from squaric acid. Several quinone derivatives are known to have antitumor and antibiotic activities. In this research, by combining ferrocene and quinone moieties, we have targeted ferrocenyl quinones which are supposed to have enhanced potential antitumor activity. Thermolysis of ferrocenyl-substituted 4-alkynyl cyclobutenones, which have been prepared from ferrocenyl cyclobutenediones and alkynyllithiums, leads to the formation of ferrocenyl quinones and besides also cyclopentendiones are observed. Ferrocenyl cyclobutenediones have been prepared from known cyclobutenediones by nucleophilic addition of ferrocenyllithium followed by hydrolysis. A mechanism for the formation of ferrocenyl substituted quinones, involving first electrocyclic ring opening of alkynyl substituted cyclobutenone to ketene intermediate and then ring closure, has been proposed. Polyquinanes are widely found in nature and proved to have biological activity such as antibiotic activity. For the synthesis of ferrocenyl polyquinanes, starting from squaric acid, ferrocenyl substituted cyclobutenediones were prepared and reacted with alkenyllithium, and hydrolyzed to afford ferrocenyl substituted polyquinanes. A mechanism has been proposed that involves first the formation of cis- and trans-divinyl substituted cyclobutenes that produce cyclooctatriene-dienolate, upon hydrolysis of this dienolate, aldol-type transannular ring closure reaction takes place, producing polyquinanes.
Han, Nam Fong. "Soluble and polymer-bound palladium and platinum complexes of ferrocene derivatives." Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/27312.
Full textScience, Faculty of
Chemistry, Department of
Graduate
Saku, Duduetsang. "Synthesis and characterization of symmetrical and unsymmetrical ferrocenyl ligands for use in the preparation of Redox Active Ruthenium Alkylidene Complexes." Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/701.
Full text