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1

Wahyuono, Subagus. "PHYTOCHEMICAL INVESTIGATION OF AMSONIA GRANDIFLORA FAMILY APOCYNACEAE." Thesis, The University of Arizona, 1985. http://hdl.handle.net/10150/275413.

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2

Absalom-Hornby, Victoria. "An investigation into family intervention within forensic services." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/an-investigation-into-family-intervention-within-forensic-services(2b4fe05a-64e3-4383-a4ff-cdbafc809011).html.

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Schizophrenia is a severe and chronic disorder in many cases. The illness can impact on the whole family. Family interventions are a psychosocial treatment for schizophrenia. A robust evidence base has developed supporting the use of family interventions, as reduced relapse and other clinical benefits can be produced. The majority of service users in forensic services suffer from schizophrenia. Yet little is known about the need, acceptability or feasibility of family intervention in forensic services. The over-arching goal of this programme of research was to review the literature for family intervention and conduct a comprehensive needs assessment, with a final aim to resolve the barriers of implementation of family intervention within forensic services. Meta-analysis indicated that the efficacy of family interventions resulted in positive outcomes in reduced relapse and psychotic symptoms, and improved knowledge and relationships. Family interventions were found to be applicable to the psychological needs of forensic service users. Problems were identified with staff training and supervision on forensic wards, with few wards providing family intervention as part of treatment for schizophrenia. Relatives of forensic service users expressed a need for family intervention. Staff highlighted that the barriers to family intervention were associated with insufficient time, poor support, lack of training, deficient information sharing, and geographic limitations between family homes and the forensic units. Staff offered solutions to implementing family intervention that related to revised policy and improved supervision. Relatives and staff held positive attitudes toward family intervention with open-minded attitudes towards the use of a web camera to facilitate family intervention in forensic services (e-FFI). The fourteen week web based family intervention (e-FFI) feasibility study generated reduced levels of stress, stigma and expressed emotion with improvements in the family’s knowledge of schizophrenia, personal health and an acceptance of forensic services. E-FFI was administered with ease achieving positive feedback from the family and the forensic service.
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3

Schwarz, Patrick. "Capital Structure and Profitability in German Family Firms : An Investigation of stock market listed family and non-family firms." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-260101.

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4

Willers, Magnus. "Family Businesses and their Industries An Investigation of listed Family Businesses in Switzerland and Germany /." St. Gallen, 2008. http://www.biblio.unisg.ch/org/biblio/edoc.nsf/wwwDisplayIdentifier/02603744002/$FILE/02603744002.pdf.

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5

Tomkins, Janine. "Molecular and evolutionary investigation of the phosphoglucomutase gene family." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362936.

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6

Haumann, Carel Eduard. "Investigation of an atypical protoporphyric family in South Africa." Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/11184.

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Includes bibliographical references (leaves 171-184).
Affected members of the family investigated in this dissertation presented with photosensitivity and raised red cell protoporphyrin concentrations, indicative of protoporphyria. Further examination of this family revealed features that were atypical of erythropoietic protoporphyria. These included a highly penetrant disease, disease severity as expressed by more prevalent hepatic complications, a preponderance of protoporphyrin in its zinc chelated form, a therapeutic response to iron supplementation, and an absence of mutations in the ferrochelatase gene or haplotype markers associated with erythropoietic protoporphyria. We have reviewed clinical data from this family, established a ferrochelatase enzyme assay in our laboratory, and shown normal ferrochelatase enzyme activity in affected subjects.
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7

Hughes, Charles Daniel. "AN INVESTIGATION OF FAMILY RELATIONSHIPS FOR PEOPLE WHO STUTTER." Bowling Green State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1174423351.

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8

Hassan, Abul. "Chemical investigation on some Indian medicinal plants (Flacourtiaceae family." Thesis, University of North Bengal, 1989. http://hdl.handle.net/123456789/873.

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9

Georgiou, Melina. "Investigating commitment to the family of origin as a correlate of subjective wellbeing." Diss., University of Pretoria, 2013. http://hdl.handle.net/2263/40453.

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10

Lawton, J. C. "Investigation of the cir multi-gene family of Plasmodium chabaudi." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1338585/.

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The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and rodent malaria species. Despite their almost universal presence, little is known about the functions of the PIR proteins. To investigate the role PIR proteins play during the erythrocytic stages of infection, the P. chabaudi model was chosen, where this gene family is termed cir. 198 cir genes were identified in the P. chabaudi genome, 86% of which clustered to form two major sub-families on the basis of sequence similarity. Quantitative RT-PCR and Illumina RNA sequencing were used to investigate cir transcription during P. chabaudi infection. Both methods detected many cir genes transcribed at low levels, as shown previously for other pirs. Three of the transcribed cir genes were selected for recombinant protein expression in the yeast Pichia pastoris: PCHAS_000100, PCHAS_070130 and PCHAS_040110. Soluble PCHAS_000100 was used for measurements of CIR secondary structure. Conserved and sub-family specific peptides were also synthesized. Antibodies present in the sera of P. chabaudi immune mice recognized all CIR proteins and peptides. Polyclonal antibodies were used to determine CIR localization by confocal microscopy and flow cytometry. Whilst most CIRs were located within the parasites, some CIRs were also found on the infected erythrocyte surface of mature trophozoites. In addition, CIRs were detected at the apical end of merozoites. These results imply that CIR proteins are exposed to the immune system during P. chabaudi infection and are antigenic, yet immunization with most CIR proteins and peptides did not protect mice from P. chabaudi infection. Upon P. chabaudi challenge of mice immunized with CIR sub-family specific reagents, increased levels of cir transcripts belonging to the other major sub-family were detected. This may explain why few differences in parasitaemia were observed. The exception was observed during P. chabaudi challenge of mice immunized with PCHAS_000100, which were able to clear parasitaemia earlier than controls.
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11

Lees, Kerri T. "Exploring fathers' experience of behavioural family therapy : a qualitative investigation." Thesis, London Metropolitan University, 2013. http://repository.londonmet.ac.uk/697/.

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Behavioural Family Therapy (BFT) as a family intervention has previously been evaluated, with specific attention to its effectiveness in reducing relapse rates in psychosis. Less research, however, has focused on the subjective experiences of having BFT and no known research has explored fathers’ experiences of BFT. More generally, limited research has explored fathers’ experiences across other types of family therapy. This is interesting in the light of theories suggesting fathers benefit from family approaches and are considered to play an important part in them (Martin, 1977). A gap in contemporary literature provided a solid rationale to explore this concept further. This research represents an original investigation into the subjective experiences of fathers who have participated in BFT. Semi-structured interviews were carried out with five fathers to explore their experience of BFT. Interpretative Phenomenological Analysis (IPA) was used to analyse verbatim transcripts which generated three themes: Fathers’ Reflections prior to BFT, Fathers’ Reluctance about BFT and Fathers’ Positive views of BFT. The results were considered in relation to existing research in this field, with reference to counselling psychology philosophy. The findings highlighted specific reservations fathers have about the process of family therapy, and drew attention to the significance of engaging fathers in family interventions. This study contributes to knowledge by considering how the above themes inform counselling psychology, other clinical practice, service provision and training. The implications for future research are also discussed.
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12

McGovern, Rachel Adams. "Fortifying Leisure: A Qualitative Investigation of Family Leisure in Uganda." BYU ScholarsArchive, 2010. https://scholarsarchive.byu.edu/etd/3096.

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The purpose of this study was to examine leisure patterns and meanings of leisure among families in the developing East African nation of Uganda, in response to recent calls for more non-Western leisure studies (Chick, 1998; Iwasaki, Nishino, Onda & Bowling, 2007). The three focus questions answered in this study were: (a) what do Ugandans from the Mukono District think leisure is? (b) how is family leisure, in their terms, happening? and (c) in what ways do they think family leisure is important? This study utilized a grounded theory methodology (Glaser & Strauss, 1978) with qualitative data analysis methods. Sixty-eight secondary students and five family units were interviewed. The data were analyzed using open, axial, and selective coding. Results indicate Ugandan definitions of leisure are similar to Western definitions. Additionally, Ugandan families participate in activities similar to Western families. Students mentioned five primary family leisure outcomes (enjoyment/fun, personal development, family development, health, and relaxation) that point toward a core theme. Fortifying describes the importance Ugandan students and family members place upon family leisure outcomes that strengthen the individual to overcome inevitable challenges they will face throughout their lives and enable them to succeed. Additionally, participants frequently mentioned the role of family socializing activities, such as discussion and story-telling, in contributing to important family leisure outcomes.
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13

Way, Jacqueline Mary. "The family interaction test : an investigation of the validity and reliability of a projective test of family interaction /." Title page, contents and abstract only, 1986. http://web4.library.adelaide.edu.au/theses/09ARPS/09arpsw357.pdf.

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14

Holak, Karina. "Investigation of murine cytomegalovirus US22 gene family members m139 and m142." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-76614.

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15

Spence, M. S. "Family based investigation of the genetic basis of ischaemic heart disease." Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268983.

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16

Garland, Patrick. "Molecular investigation of the MAST kinase family in the mammalian CNS." Thesis, University of Southampton, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.478886.

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17

Mariani, Elena. "The relationship between family context and job satisfaction : a quantitative investigation." Thesis, London School of Economics and Political Science (University of London), 2017. http://etheses.lse.ac.uk/3590/.

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This thesis provides empirical evidence on the relationship between demographic events and job satisfaction. Existing conceptualisations of job satisfaction are not fruitful for theorising the relationship between family context and job satisfaction. I develop a framework whereby job satisfaction is maximised when there are no mismatches between desired and obtained employment characteristics, while desired employment characteristics are in turn affected by family context. On one hand, family events may create negative spill-overs into well-being at work; on the other hand, work may be a buffer against negative family events. As family context I consider motherhood, length of paid leave after birth of a child for women and marital dissolution for men. I use the German Socio-Economic Panel (SOEP), a longitudinal survey representative of German households that spans the period 1984–2013. This dataset is ideal for my research question because it is the longest panel survey of job satisfaction. Although I chose the SOEP due to its high suitability, I also exploit features of German society and policy. I show that family events bring about variations in job satisfaction in unexpected ways. Becoming a mother does not matter for trajectories of job satisfaction. However, factors such as availability of suitable employment and norms may be more important in explaining why childless women have lower job satisfaction than mothers in Eastern Germany, but not in Western Germany. A shorter paid leave brings about a lower level of job satisfaction at the return to work but only for women of a lower socio-economic standing. Men who divorce experience a temporary increase in job satisfaction that lasts for up to three years after marital dissolution.
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18

Bouamatou, Leila. "A QUALITATIVE INVESTIGATION OF FEMALE FAMILY BUSINESS SUCCESSION IN FRANCOPHONE AFRICA." Diss., Temple University Libraries, 2017. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/424613.

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Business Administration/International Business Administration
Ph.D.
Family businesses are a critical part of the African economy, yet many fail within one generation and most within two generations. Moreover, women are generally not part of leadership succession in family businesses due largely to institutional logics that serve as impediments to women in business leadership. The intent of this dissertation is to fill a gap in the research literature and knowledge on the experiences of female successors in African family businesses by investigating the influence of institutional logics (cultural, ownership, management and family factors) on the leadership succession of women in African family business. A qualitative study consisting of semi-structured interviews was conducted with eight female leadership successors in African family business representing different industries. Participants were asked about their perceptions about being a woman in business, the nature of female succession in family-owned businesses, and impediments they perceive to the success of women in business. Ultimately, the findings uncovered various institutional, familial and individual impediments to women taking on leadership roles, such as institutional attitudes towards women, gender stereotypes, masculine attitudes of entrepreneurship, a lack of access to resources, and access to education and training amongst girls and women. Overall, this research contributes to theory and knowledge on how women’s succession in a family firm is affected by institutionalized African legal and sociocultural norms’ and the impact of management, ownership and family elements in family businesses.
Temple University--Theses
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19

Liu, Suyu. "Wages, family background, on-campus performance and gender : an investigation of Chinese graduates' first job salaries." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:204bcd0c-ff1c-493a-8796-8d50c91c315d.

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The last five decades have witnessed an increasing interest in the education-employment transition. In China, millions of university students graduate each year. Their employment has important impact on various aspects of the Chinese society. Additionally, university-work transition is related to the well-being of university graduates and their families. Therefore the university-work transition in China deserves more attention from scholars and practitioners. This thesis examines the determination of Chinese university graduates’ first job salaries. It investigates whether and how university graduates’ family background, on-campus performance (OCP) and gender are linked with their first job salaries. The thesis distinguishes three dimensions of graduates’ family background: Hukou status, parental CCP membership and income. It distinguishes three dimensions of graduates’ OCP: academic achievements, professional capability and political/ideological attainment. Information collected through interviews is used to interpret the statistical results. The results show that graduates’ first job salaries are significantly affected by their professional skills, political/ideological attainments and family income. Graduates’ gender, academic performance and family Hukou status have little impact on their first job salaries. Compared with the widely observed wage disparities among less educated workers caused by gender and Hukou status, this thesis provides evidence that higher education helps reduce the gender wage gap and rural-urban disparity in China. Analyses in the thesis are consistent with ‘state as equalizer’ and ‘market as equalizer’ theories. This thesis provides little evidence to support the marketized transition theory, as we find graduates’ first job salaries are still largely affected by their political/ideological attainments in university. Considering the unique context, the results suggest that some widely used human capital indicators and productivity signals are not applicable in the Chinese labour market. Practical implications are derived from the thesis.
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20

Martin, Christopher John. "SME ownership succession : an investigation using an intellectual capital lens." Thesis, Birmingham City University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272092.

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21

Wallis, Andrew. "Family Based Treatment for Young People with Severe Anorexia Nervosa: An Investigation of Outcome, Family Functioning and Relationship Change." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/17856.

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Family functioning (FF) and adolescent-parent attachment are important treatment outcomes. Knowledge about these domains during Family-Based Treatment (FBT) for Anorexia Nervosa (AN) is limited, warranting further investigation. FBT response for patients with high levels of eating disorder psychopathology, psychiatric comorbidity and acute medical instability before outpatient care is less clear. This is crucial because illness severity is generally related to poorer outcome, and families in this situation are of particular interest because the impact of AN is likely to be more pronounced, and FBT less successful. The main aim of this thesis was to investigate FF and adolescent-parent attachment from adolescent, mother and father perspectives, in a severely unwell group of patients who were part of a randomised control trial. Four studies were completed using quantitative and qualitative methods. Study 1 compared AN adolescents, mother and fathers treated with FBT and non-clinical families longitudinally. Study 2 employed grounded theory to interview adolescents and parents from the same family about relationship changes during FBT. Study 3 investigated the effect of baseline, and changes in, FF and adolescent-parent attachment on remission in the short and longer term. Study 4 explored FBT dose and remission outcome post hoc. The findings of this thesis indicate generally low FF impairment levels, with AN and non-clinical adolescents similar, and AN parents indicating poorer functioning, although fathers in both groups perceived increased difficulty over time. Adolescents who perceived poorer FF at baseline were less likely to remit. There were few positive changes in FF during or after FBT in the quantitative studies. Qualitatively this was not the case, and improved family functioning and relationships were reported, and change mechanisms identified. Future research to investigate how to augment FBT to better meet the psychosocial needs of families is warranted.
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Chung, Mei-ling. "An exploratory study of a family focussed framework for social enquiry in a probation setting /." [Hong Kong : University of Hong Kong], 1987. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12341642.

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23

Koekemoer, Evan. "An investigation into the family life cycle within a South African context." Thesis, Nelson Mandela Metropolitan University, 2006. http://hdl.handle.net/10948/191.

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Each individual/household progresses through the family life cycle (FLC). This progression, which is characterized by various stages and varying consumption portfolios, can be traditional or non-traditional in nature. In the general marketing sense, the FLC concept has great value. The concept is utilized in a variety of marketing activities, particularly in segmentation, and is also applied in consumer behaviour. The lack of research regarding the FLC in South Africa and the need to investigate the concept’s applicability to different environments motivated this research. The aim of the study was to determine how the FLC within a South African context compared to the theoretical depiction of the concept. The evaluation of literature revealed five distinct traditional stages and an array of non-traditional stages, determined by a combination of life stage determining variables. Regarding the empirical approach, self-administered questionnaires were distributed to a convenience sample consisting of 225 students and staff members of the then Port Elizabeth Technikon. The empirical findings revealed the following. {u100083} Non-traditional stages were more prevalent than traditional stages. ii {u100083} Marital status, the presence/absence of children and living arrangement appear to be sufficient life stage determining variables for both current and prospective life stage classifications. {u100083} The consumption portfolios of individuals in the traditional FLC were similar to theory. The research provided insight into the consumption portfolios of individuals in the non-traditional FLC. {u100083} Based on the intentions of certain individuals regarding marriage, having children and living arrangements, it appears as though the future FLC will include an integration of traditional and non-traditional progressions.
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Reddy, Koovesheni. "An investigation into work-family conflict in females occupying lower-level jobs." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1201.

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The study focused on work-family conflict among females occupying lower level jobs. A quantitative research methodology was conducted on a sample of (N=144) females working on the assembly line in two private sector organisations. The research instrument was a questionnaire comprising six parts. The variables were measured under four categories: work-family conflict, job demands, perceived organisational support and job self-efficacy. Descriptive statistics were used to analyse and interpret the data. A comparative study was done between Hesto and Alpha pharmaceutical employees and it was found that Hesto employees experience greater work-family conflict, job demands, perceived organisational support and job self-efficacy. The correlation results of the study showed that a significant negative relationship exists between perceived organisation support and work-family conflict. There was a weak positive relationship between perceived organisational support and job self-efficacy. Work demands was found to be positively and significantly related to work-family conflict. There was a significant negative relationship between perceived organisational support and work demand. A significant negative relationship was found between job self-efficacy and work-family conflict. Based on these results recommendations were made on how South African companies can help reduce work-family conflict.
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Symboluk, Amanda J. M. "An investigation of family, social and personal variables in adolescent sexual perpetrators." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0006/MQ42102.pdf.

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26

Stacey, Maria A. "Investigation of mammalian and viral Interleukin-10 family members during cytomegalovirus infection." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/40250/.

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Human cytomegalovirus (HCMV) infection in newborns and immunocompromised individuals with immature or deficient immune systems can cause life-threatening diseases. The clinical and subsequent economical burden of HCMV infection led the US Institute of Medicine designating a vaccine for HCMV as the highest level of priority. Complex virus-host interactions have developed over millions of years of co-evolution, making the understanding of the pathogenesis of HCMV disease particularly challenging. Consequently, a crucial factor in aiding the development of effective vaccinations and therapies to significantly reduce morbidity and mortality associated with HCMV infection is elucidating what immune mechanisms contribute to/impede protection against infection. For example, is the induction of immunomodulatory agents such as cytokines beneficial or harmful to the host during infection? Given the known immunosuppressive properties of one such cytokine, interleukin-10 (IL-10), in conjunction with the evolutionary acquisition by HCMV of its own IL-10 homologue, I hypothesised that mammalian- and viral-IL-10 suppress protective immunity during acute CMV infection. Utilising a mouse model of CMV infection, I revealed a surprising antiviral role for IL-10 during acute infection in vivo, which was achieved via limitation of activation-induced death of NK cells. The IL-10-related cytokine interleukin-22 (IL-22) provides critical protection against certain infectious agents and I therefore hypothesised that IL-22 provides protective immunity during acute CMV infection. Utilising the murine infection model once more, I discovered a tissue-specific antiviral role for IL-22 during acute infection in vivo and made the surprising finding that neutrophils play a protective role during infection. I also demonstrated that neutrophils can directly inhibit viral replication in vitro. Thus, novel insights into cytokine biology in the context of viral infections in vivo revealed by these studies highlighted important considerations for future research into herpesvirus infections, and has major implications for the treatment of this important infectious disease.
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Koernig, Sandra. "Investigation into the role of the 'yir' multigene family of 'Plasmodium yoelii'." Thesis, Open University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434966.

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28

Makinwa, Akinlolu. "Challenges of disintergrating family life to youth ministry : a practical theological investigation." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71889.

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Thesis (MTh)--Stellenbosch University, 2012.
ENGLISH ABSTRACT: The family as an indispensable social institution meant to serve as the first place of socialization, nurture and spiritual training ground for young people is disintegrating. The signs for disintegrating family life are evident and supported by statistics of high rates of divorce, domestic abuse and violence, juvenile delinquency caused by a lack of genuine nurturing of youth and unresolved family conflicts between husband and wife as well as between parents and children. This has become a global issue. This study therefore investigates the challenges of disintegrating family life to youth ministry from a global perspective by studying materials on global families and youth ministry. The aim of the study is to gain a conceptual understanding of the family, to identify the challenges contemporary families are currently facing, and to find ways in which youth ministry, with the help of young people, can respond to the challenges posed by disintegrating family life to their lives and thereby contribute to the reintegration of their present families while laying a good foundation for their future family for the glory of God and benefit of humanity. Since the family and youth are inseparable, the research studies the context of the disintegrating family, identifies causes and consequences of disintegrating family life as well as the challenges posed by disintegrating family life for youth ministry. Osmer‟s four practical theology questions are used to design this study. These are: what is going on, why is this going on, what ought to be going on, and how might we respond In light of the increase in family disintegration, the main research question is: What are the challenges of disintegrating family life to Youth Ministry? The aims of youth ministry are taken as the norm and these are: effective evangelism; comprehensive education that includes Christian education; financial education; health education; marriage and family life education, as well as pastoral care. The study argues that young people converted to Christ, taught and exposed to pastoral care can be active agents of change in their immediate and future family and thus becomes active agents of change in society. However, with millions of orphans, youth in refugee camps, children affected by divorce, and youth in child-headed families, can youth workers cope with the present and future challenges of disintegrating family life to youth ministry? The study proposed the God-bearing, relational and family-based-youth-ministry approach because the three approaches are deemed to be the most appropriate to enable youth ministry to deal with the challenges. Marriage and family life education is highly recommended as a prerequisite for contemporary evangelised and educated young people. This is to serve, firstly, as a reactive measure to help their immediate disintegrating family and secondly, to serve as a proactive measure to lay a solid foundation for the future family of contemporary youth. This, I hope, will be used by God to help curtail the vicious cycle of the disintegrating family life phenomenon and also bring relief to troubled youths, family and society.
AFRIKAANSE OPSOMMING: Die familie as `n noodsaaklike sosiale instelling wat bedoel is om te dien as die eerste plek van sosialisering, versorging en spirituele opleidingsgrond vir jongmense, is besig om te verbrokkel. Verbrokkelende familielewe is duidelik sigbaar en die tekens word bevestig deur statistieke van hoë syfers in egskeidings, huishoudelike mishandeling en geweld en jeugmisdadigheid wat veroorsaak word deur `n gebrek aan werklike versorging van jeugdiges en onopgeloste familie konflik tussen man en vrou, asook tussen ouers en kinders. Hierdie situasie het `n globale een geword. Die studie ondersoek om hierdie redes die uitdagings van verbrokkelende familielewe op jeugbediening vanuit `n globale perspektief deur bronne te bestudeer van globale families en jeugbediening. Die doel van die studie is dus om `n konseptuele verstaan van die familie te bekom, om die eise wat hedendaagse families ondervind te identifiseer, en om maniere te vind waardeur jeugbediening, met die hulp van jongmense, die uitdaging van verbrokkelende familielewe kan aanspreek. Sodoende kan jeugbediening bydra tot die herintegrasie van huidige families, en terselfdertyd `n goeie fondasie lê vir toekomstige families vir die glorie van God en tot voordeel van die mensdom. Aangesien die familie en jeug onskeibaar is, bestudeer hierdie navorsing die konteks van die verbrokkelende familie, identifiseer oorsake en gevolge van verbrokkelende familielewe, asook die uitdagings wat dit bied vir jeugbediening. Osmer se vier praktiese teologie vrae is gebruik in die studie-ontwerp. Dit behels: wat gaan aan, hoekom gaan dit aan, wat moet aangaan en hoe gaan ons reageer. In die lig van die styging in familieverbrokkeling, is die hoof navorsingsvraag: Wat is die uitdagings van die verbrokkelende gesinslewe op jeugbediening? Die doel van jeugbediening word geneem as die norm en dit behels: effektiewe evangelisasie, omvattende opleiding wat insluit Christelike opleiding, finansiële opleiding, gesondheidsopleiding, huweliks- en familielewe opleiding, sowel as pastorale sorg. Die studie argumenteer dat jongmense wat bekeer is tot Christus, en opgelei en blootgestel is aan pastorale sorg, aktiewe agente van verandering kan wees in hulle onmiddelike en toekomstige families en daardeur aktiewe agente van verandering in die samelewing kan word. Tog is daar miljoene weeskinders, jongmense in vlugtelingskampe, kinders wat geaffekteer is deur egskeidings, en kinders in huise wat deur kinders self beman word. Die vraag is – kan jeugwerkers die huidige en toekomstige uitdagings wat familieverbrokkeling op jeugbediening plaas hanteer? Die studie stel twee benaderings voor wat die meeste geskik is om jeugbediening in staat te stel om die probleem te hanteer, naamlik die God-draer en die familie-gebaseerde jeugbediening benaderings. Opleiding in die huwelik en familielewe word voorgestel as voorvereistes vir hedendaagse ge-evangeliseerde en opgeleide jongmense om sodoende eerstens te dien as `n reaktiewe maatreël om hulle onmiddelike verbrokkelende familie te help, en tweedens, om te dien as `n proaktiewe maatreël om `n soliede grondslag te lê vir die toekomstige families van hedendaagse jeug en die samelewing. Hierdeur kan die fenomeen van verbrokkelende familielewe beperk word.
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Alshafai, Mashael Nedham A. J. "Family-based investigation of the genetics and epigenetics of obesity in Qatar." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/31860.

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Single nucleotide polymorphisms (SNPs), copy number variations (CNVs) and DNA methylation patterns play a role in the susceptibility to obesity. Despite the alarming figures of obesity in the Arab world, the genetics of obesity remain understudied in Arabs. Here, I recruited ten multigenerational Qatari families segregating obesity, and generated genome-wide SNP genotyping, whole genome sequencing and genome-wide methylation profiling data using Illumina platforms to investigate the role of rare mutations, CNVs, and DNA methylation patterns in the susceptibility to obesity. For the identification of obesity mutations, I first identified candidate obesity regions through linkage and run of homozygosity analyses, and then investigated these regions to detect potential deleterious mutations. These analyses highlighted putative rare variants for obesity risk at PCSK1, NMUR2, CLOCK and RETSAT. The functional impact of the PCSK1 mutation on obesity was previously demonstrated while for the other candidates further work is needed to confirm their impact. For the identification of common obesity CNVs, I performed a genome-wide CNV association analysis with BMI and identified a common duplication of ~5.6kb on 19p13.3 that associates with higher BMI. Moreover, I investigated large (≥500kb) rare CNVs and identified a ~618kb deletion on 16p11.2 in the most extremely obese subject in my samples, which confirms the contribution of the previously reported 16p11.2 deletions to severe obesity beyond European populations. For the identification of DNA methylation changes in obesity, I attempted to replicate known associations with BMI from large EWASs. I replicated the associations at ABCG1 (P-value=6.3X10-3) and CPT1A (P-value=8.7X10-5) and compared the effects observed to the TwinsUK cohort through a meta-analysis. I observed low heterogeneity between the two studies, and that increased the associations at ABCG1 (P-value=2.5x10-13) and CPT1A (P-value=1.9x10-15). In conclusion, the work represents the first genetic and epigenetic study of obesity in an Arab population. I replicated known genetic and epigenetic obesity susceptibility loci and also discovered novel potential loci.
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Armaly, Timothy John. "Delinquents' perceptions of family upbringing, an interpretive interactionist investigation of family patterns common in the youth of criminally charged adults." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ30862.pdf.

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31

Graff-Dolezal, Jennie. "Measure what works a focus group investigation of the session rating scale /." Menomonie, WI : University of Wisconsin--Stout, 2005. http://www.uwstout.edu/lib/thesis/2005/2005graff-dolezalj.pdf.

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32

October, Kezia Ruth. "An investigation into the correlates of family resilience in an impoverished rural community in the Western Cape." University of the Western Cape, 2018. http://hdl.handle.net/11394/6347.

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Magister Artium - MA (Psychology)
Families in South Africa are faced with manifold hardships that negatively impact the family as a unit. However, there are a variety of protective factors that have been identified as meaningful resources that facilitates healing and growth within a family unit. The study aims to investigate whether age, gender, employment status and level of education significantly predicts family resilience. The study utilised secondary data compromised of (N=656) participants from a low socio-economic rural community in South Africa. Family resilience views the family as a functional system of which provides positive adaption to family members who have experienced stressful events. Walsh's key processes in family resilience is outlined, highlighting a multi-level developmental systems orientation. The study utilised a multiple regression analysis consisting of four predictor variables namely, age, gender, employment status and level of education to assess whether these variables predict high levels of family resilience. The model found that amongst the four predictor variable, only employment status significantly predicted family resilience.
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Friedman, Jeffrey Michael. "A Grounded Theory Investigation of Adaptations to Adverse Childhood Experiences." Diss., NSUWorks, 2018. https://nsuworks.nova.edu/shss_dft_etd/32.

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Adverse childhood experiences (ACEs) include childhood sexual abuse, physical abuse, emotional abuse, physical neglect, emotional neglect, and household dysfunction. Much has been reported about the detrimental outcomes associated with these experiences. The associated negative outcomes of ACEs can include addiction, suicide, disability, teenage pregnancy, and early death. However, it is well known that many people experience ACEs and do very well. Rather than viewing negative outcomes only as symptoms of trauma and positive outcomes only as signs of resilience, it is possible to consider adaptations. This study focused on how adults adapted to their adverse childhood experiences. Data were collected based on semistructured interviews with nine members of the ACEs Connection Social Network, an online support group. The data were analyzed using a constructivist grounded theory methodology. A grounded theory then emerged from data, supporting the adaptation construct.
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Eze, Nonyelum Lina. "Informal institutions and their influences on the family, the family business, and ethnic group: A macro-, meso-, and micro- context investigation." Doctoral thesis, Universitat Ramon Llull, 2021. http://hdl.handle.net/10803/671126.

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Les influències de les institucions informals sobre la família, les empreses familiars i els grups ètnics són immenses a causa de la integració d'aquestes organitzacions en el seu context local, que és on s'originen la majoria de les institucions informals. Malgrat això, quan les institucions funcionen de manera eficaç, sovint suposem que són les regles formals les que condueixen els comportaments dels actors. Tot i això, les normes informals subjacents poden complementar, substituir o acomodar les institucions formals, o també competir-hi. Els estudis previs sobre institucions informals estan dispersos i fragmentats, i presenten les institucions informals com a ambigües. Aquesta tesi aporta llum sobre les institucions informals que configuren la família, les empreses familiars i els grups ètnics d'un país en vies de desenvolupament per produir resultats emprenedors. Una revisió sistemàtica dels materials publicats és un punt de partida vital, ja que permet comprendre i conciliar els estudis existents, i subratllar àrees en les quals falta investigació. La revisió dels materials publicats va seguida de dues investigacions qualitatives. El primer estudi qualitatiu se centra en la religió i les tradicions —institucions informals substitutives— per entendre com transmeten trets familiars i pràctiques empresarials que fomenten o dificulten l'emprenedoria transgeneracional. El segon estudi qualitatiu explora el procés mitjançant el qual un grup ètnic s'ancora en un sistema d'aprenentatge informal —una institució informal en competència— per fomentar la creació de valor intergeneracional i, el que és més important, la propagació de l'emprenedoria. En fer-ho, aquest treball ofereix diverses contribucions que amplien la comprensió teòrica en els contextos de l'empresa familiar, l'emprenedoria i un grup ètnic en un país en vies de desenvolupament. Els seus descobriments poden orientar els professionals i els responsables polítics.
Las influencias de las instituciones informales en la familia, las empresas de gestión familiar y el grupo étnico son inmensas debido al arraigo de estas organizaciones dentro de su contexto local, que es donde se originan la mayoría de dichas instituciones informales. A pesar de ello, cuando estas instituciones funcionan de manera eficaz, solemos asumir que son las reglas formales las que impulsan el comportamiento de los distintos protagonistas. Sin embargo, las normas informales subyacentes pueden complementar, sustituir, acomodar o competir con las instituciones formales. Los estudios anteriores sobre las instituciones informales están dispersos y fragmentados, y presentan a las instituciones informales con un carácter ambiguo. Esta tesis arroja luz sobre las instituciones informales que dan forma a la familia, las empresas de gestión familiar y el grupo étnico en un país en desarrollo a fin de producir resultados empresariales. Una revisión sistemática de la literatura existente es un punto de partida fundamental, ya que permite comprender y conciliar los estudios previos y subrayar las áreas en las que es necesaria una mayor investigación. A la revisión de esta literatura le siguen dos trabajos de investigación cualitativa. El primer estudio cualitativo se centra en la religión y las tradiciones (instituciones informales sustitutivas), para comprender cómo infunden aspectos familiares y prácticas comerciales que fomentan o dificultan el espíritu empresarial transgeneracional. El segundo estudio cualitativo explora el proceso por el cual un grupo étnico queda anclado a un sistema de aprendizaje informal (una institución informal competitiva) para fomentar la creación de valor intergeneracional y, lo que es más importante, la propagación del espíritu empresarial. Gracias a ello, este trabajo ofrece diversas contribuciones que amplían la comprensión teórica en los contextos de las empresas de gestión familiar, el espíritu empresarial y un grupo étnico determinado en un país en desarrollo. Sus conclusiones pueden servir de guía a profesionales y legisladores.
The influences of informal institutions on the family, family businesses, and the ethnic group are immense due to these organizations' embeddedness within their local context, which is where most informal institutions originate. Despite that, when institutions function effectively, we often assume that it is the formal rules that drive actors' behaviors. Yet the underlying informal norms may complement, substitute, accommodate, or compete with formal institutions. Previous studies on informal institutions are scattered and fragmented, and present informal institutions as ambiguous. This thesis sheds light on the informal institutions that shape the family, family businesses, and the ethnic group in a developing country to yield entrepreneurial outcomes. A systematic literature review is a vital starting point as it allows for understanding and reconciliation of existing studies and underscoring areas where research is lacking. The literature review is followed by two qualitative research pieces. The first qualitative study focuses on religion and traditions—substitutive informal institutions—to understand how they imbue family features and business practices that foster or hinder transgenerational entrepreneurship. The second qualitative study explores the process through which an ethnic group anchors on an informal apprenticeship system—a competing informal institution—to foster intergenerational value creation and, more importantly, entrepreneurship propagation. By doing so, this work offers several contributions that extend theoretical understanding in the contexts of the family business, entrepreneurship, and an ethnic group in a developing country. Its findings can guide practitioners and policymakers.
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Stoeckel, Helen, and n/a. "An investigation of the readjustment experience for secondary exchange students : a family perspective." University of Canberra. Professional & Community Education, 1997. http://erl.canberra.edu.au./public/adt-AUC20061109.093814.

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This study of the process of readjustment for secondary students returning home after twelve months abroad was investigated from a family perspective. Although researchers suggest that interactions between the student and others in the home environment facilitate smooth readjustment, little is known about how the family relates during this transition period. In this study, the interactional dynamics within the family during the student's readjustment were explored. Theoretical concepts from systems theory and family developmental theory were used to further understanding of the interactional processes within the family system. A multiple single-case study research design was employed, where eight families were interviewed at three points in time: one month before the student's return; one month after the student's return: and at four to five months after return. All family members were interviewed at each stage, using a semi-structured interview guide designed to gather data about family relationships during this period. Changes in family dynamics between siblings, the returnee student, and parents, were a significant finding of this study, although these changes varied across families. A family perspective of the readjustment process was collated from descriptive accounts from family members, where four phases of the family experience could generally be described: excitement, uncertainty, rediscovery and reorganisation of the family system. It was concluded that the study showed evidence that the readjustment process was influenced by the interactions and interrelationships within the family, where not only the student had changed but also the family.
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Thompson, Martin John. "Investigation of the effects of HLS5 : a novel member of the RBCC family." University of Western Australia. School of Medicine and Pharmacology, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0106.

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[Truncated abstract] Erythropoietin (Epo) is a glycoprotein hormone involved in the formation of erythrocytes, by controlling survival, differentiation and proliferation. The technique of cDNA Representational Difference Analysis was utilized to investigate J2E-NR cells that demonstrate a viability response to Epo, but not differentiation or proliferation. The aim of this project was to identify genes that may be upregulated in response to Epo-induced survival; however, no change in gene expression was detected. This was most probably because any changes were below the limit of detectability for the cDNA RDA technique, or the viability effect was mediated post-transcriptionally. Next, it was decided to investigate HLS5, a putative tumour suppressor that was identified in a myeloid variant of the J2E cell line and had been shown to cause apoptosis. A number of HeLa cell lines inducible for Hls5 expression using the tet-off system were produced; despite extremely low expression, Hls5 was shown to produce marked suppression of growth and proliferation, particularly in colony assays colony size and numbers were halved for one induced clone. … A number of haemopoiesis-associated genes were downregulated (viz. globin genes and the Epo receptor gene), which suggested Hls5s role in the myeloid variant of J2E cells, may be to suppress genes expressed in the erythroid lineage. In addition, several interferon-responsive genes were decreased in cells with elevated HLS5, suggesting it may play a role in negatively regulating interferon signaling. Online databases were also searched for information on HLS5, and showed that it is significantly downregulated in liver, lung and uterine cancers, supporting the proposition that HLS5 is a tumour suppressor gene. In summary, a number of approaches were taken to identify the effects of the Hls5 protein. It appears that it strongly suppresses proliferation and that this is likely mediated through an effect on mitosis. This may also result in apoptosis of overexpressing cells. It is possible that this is the mechanism through which HLS5 exerts its potential tumour suppressor function, as a number of tumour suppressors appear to be associated with mitosis/apoptosis control. Hls5 is also likely to have other functions in haemopoietic cells, which includes downregulation of erythroid-specific genes and suppression of interferon responses.
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37

Radeva, Ekaterina. "A numerical investigation of a family of frontal cyclogenesis events during CASP II." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23932.

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In this thesis, a series of (48-60 h) numerical simulations of a family of frontal cyclogenesis events that occurred over western Atlantic Ocean during 13-15 March 1992 are conducted using a nested-grid version of the PSU/NCAR mesoscale model (MM4) with a fine-mesh grid size of 30 km. It is shown that MM4 captures very well the genesis, track and intensity of three secondary cyclones, their associated thermal structure and precipitation pattern as well as their surface circulations.
It is found that an upper-level potential vorticity (PV) ring plays an important role in determining the initiation and track of the frontal cyclones. The cyclones appear to form as a consequence of the superposition of upper-level PV anomalies on the low-level intense baroclinicity in the cold sector behind the slow moving primary cold front, and then they propagate into colder air towards the parent cyclone's center. It is also found that as the MFC intensifies, a mesoscale trough is induced in the low-to-middle troposphere, creating a favorable phase lag between the new pressure trough and a slow moving thermal wave. This phase lag provides a baroclinic conversion mechanism by which the system's kinetic energy could increase rapidly at the expense of available potential energy.
Diagnosis of sensitivity experiments reveals (i) dry dynamics determines the initiation and track of the frontal cyclones, accounting for about 59% of the final intensity of the MFC; (ii) the low-level baroclinicity and the upper-level PV anomalies are near-equally important in the genesis of the dry systems; (iii) the Ekman spin-down tends to slow substantially the development of the frontal cyclones; and (iv) surface heat and moisture fluxes could produce a significant impact (i.e., 59%) on the final intensity of the cyclones in the presence of latent heat release, but its impact is small in the dry dynamical framework. (Abstract shortened by UMI.)
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38

Abrahams-Salaam, Fatima. "A molecular investigation of a mixed ancestry family displaying dementia and movement disorders." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/2432.

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Thesis (MScMedSc (Biomedical Sciences. Molecular Biology and Human Genetics))--Stellenbosch University, 2008.
A South African family of Mixed Ancestry presented with a rapidly progressive dementia and a movement disorder which affected a number of individuals across three generations. The initial symptoms included personality changes and tremors that escalated to severe dementia and eventually a completely bedridden state. It was determined that the mean age at onset was in the third decade of life and affected individuals died within 10-15 years after the onset of symptoms. The aim of the present study was to elucidate the genetic cause of the disorder in this family and to further investigate the patho-biology of the disease. Mutations that could possibly cause the observed phenotype in this family were screened for. These included loci implicated in Huntington’s disease, Parkinson’s disease, Dentatorubral-Pallidoluysian Atrophy, Spinocerebellar ataxias (types 1, 2, 3, 6, and 7), Huntington’s disease-like 2 (HDL2) and several mitochondrial disorders. Single-strand Conformation Polymorphism (SSCP) analysis and direct sequencing were used to detect possible mutations while genotyping on an ABI genetic analyser was used to detect disorders caused by repeat expansions. Haplogroup and Short Tandem Repeats (STRs) analyses of the Y-chromosome and mitochondrial DNA of one affected family member was used to determine the family’s genetic ancestry. Reverse transcriptase polymerase chain reaction (RT- PCR) and complementary DNA (cDNA) analyses of the Junctophlin-3 (JPH3) gene was performed to provide information on the expression profile of this gene. After the exclusion of several genetic loci it was shown that this family had HDL2. This is a rare disease caused by a CAG/CTG repeat expansion in an alternatively spliced version of the JPH3 gene. HDL2 occurs almost exclusively in individuals of Black African ancestry. The genetic ancestry data suggested that the family member was most likely of South African Mixed Ancestry making this the first reported family of South African Mixed Ancestry with HDL2. A pilot study investigated the repeat distribution amongst three South African sub-populations in order to determine whether there was a bias in the repeat distribution that possibly predisposes Black Africans to develop the disease. The results showed a statistically significant difference (P= 0.0014) in the distribution of the repeats between the Black African and Caucasian cohorts. However, no conclusions could be drawn as to whether Black Africans harboured larger repeats that predisposes them to developing HDL2. The expanded repeat is located in an alternatively spliced version of the JPH3 mRNA. Interestingly, this repeat is not present in the mouse homologue of the gene although the rest of the genomic sequence is highly conserved across the human, mouse and chimpanzee genomes. Using foetal brain cDNA and PCR primers designed to be specific for different JPH3 isoforms, independent confirmation of the presence of two JPH3 mRNA transcripts (the full length and a shorter alternatively spliced version) was provided. In the absence of brain tissue from an HDL2-affected individual, it was investigated whether both JPH3 mRNA transcripts could be detected in lymphocytes. Using RNA isolated from the transformed lymphocytes of two HDL2-affected family members, real-time PCR was attempted. These experiments produced inconclusive results and required further optimisation. Further RT-PCR experiments for JHP3 expression in different tissues (brain and other) obtained from HDL2-affected individuals would be of interest. The present study identified the first Mixed Ancestry family with HDL2. This family will now be able to request genetic counselling and pre-symptomatic testing for all at-risk family members. Aspects of this study provided independent confirmation of characteristics of the mutated gene. More research on HDL2 will be crucial in understanding the pathogenesis of this disease.
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Shanghai, Fahimeh. "The investigation of mental health, family and religion in post-revolutionary Iranian women." Thesis, University College London (University of London), 1998. http://discovery.ucl.ac.uk/1349889/.

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The aim of this thesis is "The Investigation of Mental Health, Family and Religion in Post-Revolutionary Iranian Women". This aim was initially outlined and explored in a Pilot Study, Study 1, which outlined narrative perspectives in the form of life histories as the methodological approach to be adopted whilst drawing on psychoanalytical theory, particularly object relations theory as its underlying theoretical construction. These methodological and theoretical approaches were utilized throughout the thesis to inform the empirical studies. A series of in-depth, semi-structured, narrative interviews, coupled with multiple non-structural free flowing conversation and observation were utilized to investigate narratives as a form of life histories of adult development and depression in a group of Iranian women. Aspects of interpretative discourse analysis and interpretative phenomenological analysis was used to analyze the interview transcripts. Studies 1,2 and 3 draws on features of phenomenological heuristics and interpretative discourse analysis to elicit how women have adopted positions of 'mother', 'wife', 'daughter' and 'sister'. The analysis provides a theoretical contextualisation, addressing the role of Iranian women socio-culturally, historically, traditionally, and via the religion of Islam. Hence, specific chapters are dedicated to Islam, women's position in Iranian culture, and depression respectively. Additionally, Study 4 was conducted in conjunction with the Persian section of the BBC World Service radio. The programme "Family" was created allowing the listening audience in Iran to contact the studio in London, putting forward questions and problems to experts, i. e. psychologists and psychiatrists. The conclusion addresses the value of this genre of research methods to elicit a voice to women's life narratives. Furthermore, it is argued that there is a necessity for future research on this and related topics as significant scholarly attention on the mental health, family and religion in Iranian women has thus far been scarce.
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40

Krumpe, Sharon Wilson. "A phenomenological investigation of women's experience in family counseling: Interviews with ten mothers." W&M ScholarWorks, 2002. https://scholarworks.wm.edu/etd/1550154109.

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von, Hayek Angela. "Single mothers' experiences in family therapy: An investigation from an ego development perspective." W&M ScholarWorks, 2004. https://scholarworks.wm.edu/etd/1550154185.

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42

Logan, Caroline. "Caregiving to older people who have a dementia : an investigation of stress and coping in carers." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306888.

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43

Letele-Matabooe, Makatleho Julia. "An investigation into the factors influencing the levels of job satisfaction and organisational commitment of non-family employees working in family businesses." Thesis, Nelson Mandela Metropolitan University, 2012. http://hdl.handle.net/10948/1594.

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Given the increasingly important role that non-family employees working in family businesses play in the success of these businesses, as well as the challenges they are faced with, it is surprising that little is known about their experiences in the family business. This study therefore was aimed at contributing to the more effective functioning of this important stakeholder group in South Africa by identifying the factors that impact on their levels of job satisfaction and organisational commitment in family businesses. As such the primary objective of this study was to identify the factors that impact on non-family employees’ levels of Job satisfaction and Organisational commitment to the family business in which they are employed. This study sought to incorporate prior findings and theories on job satisfaction and organisational commitment into a comprehensive theoretical model. In addition, support for these theories was sought in the literature. The literature review revealed three main categories of constructs, namely, relational-based, organisational-based and reward-based factors, as influencing the levels of Job satisfaction and Organisational commitment of non-family employees working in family businesses. Within these three categories, 15 independent variables were identified and hypothesised to influence the levels of the dependent variables Job satisfaction and Organisational commitment. Of the 15 independent variables, 6 were categorised as relational-based, another 6 as organisational-based and 3 as reward-based factors. All of the constructs in this study were clearly defined and operationalised. Operationalisation was done by using reliable and valid items sourced from measuring instruments used by prior studies. In addition, several items were selfgenerated items based on secondary sources. The convenience snowball sampling technique was used to identify respondents, and a structured questionnaire was made available to them. The data collected 280 usable questionnaires and was subjected to various statistical analyses. The validity and reliability of the measuring instrument was assessed by means of exploratory and confirmatory factor analyses, and Cronbach-alpha coefficients were confirmed for this purpose. v The 6 relational-based factors could not all be confirmed as initially intended. Of these factors, 5 were confirmed. Similarly, the organisational-based factors could not all be confirmed by the exploratory factor analysis. Four factors were confirmed in this regard. With regard to reward-based factors, these factors did not load as originally intended. Instead, a new factor (Job security and compensation) emerged. In this study, a number of statistical procedures were utilised to assess the relationships between the independent and dependent variables. These included descriptive statistics which was used to summarise the sample data. Pearson’s Product Moment Correlation was also undertaken to establish the relationship between the various factors under investigation. However, the main statistical procedure that was used to test the significance of the relationships hypothesised between the independent and dependent variables was the Multiple Regression Analysis (MRA). From the analysis, 7 submodels were identified and subjected to further testing. The following independent variables were identified as influencing the dependent variables in this study: Fairness; Personal needs alignment; Interpersonal relationships; Family harmony; Nature of the work; Working conditions; Job involvement; Governance; Job security and compensation. In addition, an Analysis of Variance (ANOVA) was performed to establish the influence that the various demographic variables could have on the dependent variables. The test included the use of Benferroni post-hoc test that was used to vi assess the statistical difference, while Cohen’s d-values were calculated to assess the practical significance between mean scores. Ownership of shares by non-family employees of the family business in which they are employed, the positions that these employees hold, as well as ethnicity of the respondents have been found to have an influence on the independent and dependent variables in this study. This study has empirically investigated the challenges non-family employees working in family businesses are faced with, and has thus added to the limited amount of family business literature on this valuable stakeholder group. The theoretical model developed in this study has made a significant contribution towards understanding the factors that influence the levels of job satisfaction and organisational commitment of these employees. This study therefore presents recommendations and suggestions to assist family business leaders/owners in attracting and retaining non-family businesses in such a way as to give them a sense of belonging and to enhance the performance of their businesses.
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44

Klein, Marie, and Lamiaa Bakry. "Succession and Post-Succession Conflicts in Family Firms : A Multi-perspective Investigation into Succession and Post-Succession Conflicts in Multigenerational Family Firms." Thesis, Jönköping University, JIBS Entrepreneurship Centre, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-52522.

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Abstract Background The succession process of a family firm is associated with a number of challenges, and hence a potential for conflicts is strongly pronounced. However, succession is of utmost importance for a family firm, as it is the only way to avoid a company closure in the long run. Previous literature has already extensively researched the phenomena of conflicts in family firms. However, there is a lack of research that looks from a multi-perspective lens into the context of succession and post-succession conflicts. Therefore, in the present research, we examine how family businesses experience and cope conflicts that appear after a successfully mastered intrafamily succession. Purpose This study aims to advance the understanding of conflicts in family firms related explicitly to the context of successions and post-successions. Hence, the thesis aims to determine how conflicts that appear in these contexts are experienced and how they are coped with. Method The study follows a qualitative methodological approach and an inductive analysis. The sample consists of three companies and 14 research respondents, and the data was collected with semi-structured qualitative interviews. Afterwards, the data was coded, and the emerging patterns and themes have been formulated and presented with a general model. Doing so, the focus was on patterns of succession- and post-succession-related conflicts and their coping strategies. Conclusion Our findings reveal that succession and post-succession-related conflicts are experienced as evoked intangible and provoked tangible conflicts and these conflicts are consciously as well as unconsciously coped with. Furthermore, our findings suggest that succession and post-succession family firm conflicts appear as conflict loops. Hence, the coping mechanisms identified and presented are helpful to solve a conflict, but the loop can hardly be escaped.
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45

Gable, Sarah Elizabeth. "An Investigation of Stability, Change, and Observed Associations during Infant-Mother Face-to-Face Interaction." DigitalCommons@USU, 1989. https://digitalcommons.usu.edu/etd/2502.

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Researchers of social development during infancy have long viewed social competence as a reflection of the infant's experiences during early social interactions. In this context of social interaction, the infant's earliest developmental task involves the ability to regulate arousal; with continued development and the accumulation of interactional experiences, the infant takes a more active role as an initiator/elicitor of interaction. A particularly salient type of social exchange during infancy occurs when mother and infant engage in face-to-face interaction. Consequently, it was the goal of this study to examine maternal and infant behavior in the context of face-to-face interaction in order to: 1) identify those maternal behaviors that promote the infant's capacity to regulate arousal and subsequently act as a competent interactive partner; and 2) examine the extent to which early social development proceeds in a continuous manner. Thirty-one infant-mother dyads were videotaped in two 3-minute episodes of face-to-face interaction at 1 and 4 months. The first episode involved spontaneous face-to-face interaction; the second episode involved an attention-getting manipulation of maternal behavior. Maternal and infant interactive behaviors were coded for each episode at both ages. No significant differences were found in maternal or infant behavior across episodes, thus allowing for the data to be pooled. Significant findings regarding maternal behavior included the following: maternal interactive behavior was found to remain stable across time at the individual and normative levels; maternal behavior was positively associated with infant behavior at both ages; and maternal silence during infant gaze aversion was predictive of infant regulation of arousal. Conversely, infant behavior did not remain stable across time, at either the individual or normative level, thus suggesting that infants are changing. A most revealing association was discovered between 1-month maternal physical activity and 4-month infant regulation of arousal, suggesting that maternal behavior may have long-range effects on infant social competence. Consequently, from these findings, it has been suggested that maternal intrusive behaviors (e.g., physical activity, silence during infant gaze aversion) are focal in infant regulation of arousal and subsequent interactive competence.
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46

Ahmad, Ashfaq. "An investigation into programme factors and providers' perceptions at family welfare centres in Faisalabad district of Pakistan." Thesis, University of Exeter, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260790.

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47

Sherratt, Dave. "An investigation into the development of symbolic play in children with autism." Thesis, University of Warwick, 2006. http://wrap.warwick.ac.uk/89654/.

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Impairments in the use of varied, spontaneous, symbolic or imaginative play or the absence of developmentally appropriate social imitative play is of diagnostic significance in autism (Diagnostic and Statistical Manual of mental disorders, 4th edition [DSM IV] 1994). Many studies have found a poverty in play generally and particularly in spontaneous symbolic play amongst children with autism. It is then remarkable that some research studies have found that in structured settings such children are able to understand pretence and produce acts of pretence. Study 1 was a small scale study of 6 children with autism in a school setting and found that some were able to learn to play symbolically following a 4-month intervention. Structure and affective engagement emerged as 2 factors possibly mediating this improvement. Study 2 contrasted Structure and Affect each in combination with Repetition in a quasi-experimental design with 12 (different) children. Study 3, using a similar method to Study 2, additionally considered two further variables: interest in the materials and the identity of the researcher. The study showed that symbolic play acts could be elicited in the participants using high structure and high affect conditions. The use of high interest toys was less likely to elicit symbolic acts in these participants. The number of symbolic acts used by the participants were not unduly influenced by the replication of the conditions by a second researcher. A factor that possibly mediated the effects seen in Study 3 was the social-communicative responses of the participants and so Study 4 studied children with learning difficulties, four who had autism and 4 who did not, matched on verbal comprehension and examined the level of social communication responses in relation to symbolic play during three conditions of high affect, high structure and low intervention. Implications for education and further research are discussed. Results of all studies were not definitive. This represents a preliminary study to identify factors that may be effective in the teaching of symbolic play to children with autism. Some initial success with individual children indicates structure and affective engagement as factors that need to be investigated in future research.
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48

Hearn, Rebecca. "An investigation of the A6 beta-1, 3-glucanase gene family in Arabidopsis thaliana." Thesis, University of Leicester, 2002. http://hdl.handle.net/2381/29835.

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The A6 gene family represents a distinct class of P-l,3-glucanase enzymes in higher plants (Hird et al., 1993). The genes differ from other known P-l,3-glucanases in both sequence characteristics and expression pattern. The DNA sequences encode proteins with a distinctive GINYG N-terminal motif and a long C-terminal extension. The A6 gene shows tapetum-specific expression, with maximum activity detected at the time of microspore release (Hird et al., 1993). The expression pattern of A6 suggests that this gene may be part of the callase enzyme complex required for the dissolution of the callose wall surrounding the tetrads of developing microspores within the anther (Hird et al., 1993). The preliminary work on the A6 gene family identified four anther-specific cDNAs from Brassica napus (Scott et al., 1991 Hird et al., 1993). As a continuation of this work, five A6 family genes have now been cloned and sequenced in Arabidopsis thaliana. All five are single copy genes, and the three genes that have been mapped to the Arabidopsis genome are located at unlinked positions on two different chromosomes. Analysis of the cDNAs corresponding to the A6 family genes has revealed considerable variation in expression pattern. Two of the A6 family genes show anther-specific expression, and three genes are constitutively expressed, indicating differential regulatory mechanisms for these genes. Two populations of T-DNA-tagged lines were screened for four of the Arabidopsis A6 family members in attempt to obtain lines carrying mutations in these genes, which may reveal more information on their biological function(s). One positive line was identified and later shown to contain an insertion At-A6 gene. Detailed analysis of this line showed that although the At-A6 transcript in the mutant line is shorter than wild type and does contain part of the T-DNA sequence, the hybrid mRNA is stable. No phenotype could be associated with the T-DNA insertion in At-A6.
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49

Rankin, Alasdair Menzies. "An investigation of CD28/B7 family binding interactions and costimulation, using immunoglobulin fusion proteins." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360469.

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50

Couto, Elisabeth. "Investigation of the relationship between breast cancer and a family history of the disease." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439151.

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