Journal articles: 'Factors and asthma'

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Toskala, Elina, and David W. Kennedy. "Asthma risk factors." International Forum of Allergy & Rhinology 5, S1 (September 2015): S11—S16. http://dx.doi.org/10.1002/alr.21557.

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Vamos, Marina, and John Kolbe. "Psychological Factors in Severe Chronic Asthma." Australian & New Zealand Journal of Psychiatry 33, no. 4 (August 1999): 538–44. http://dx.doi.org/10.1080/j.1440-1614.1999.00591.x.

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Objective: Levels of psychological distress, social support factors, and emotional adjustment to illness were measured in a sample of patients with severe asthma. These were then examined in terms of their interrelationships and their ability to predict self-management knowledge. Method: A sample of 80 patients was recruited from a hospital-based asthma clinic designed for patients with severe asthma. Thirty-four percent of consecutive attenders approached took part. Morbidity and asthma management were recorded from case records. Anxiety, depression, social support, emotional adjustment to asthma and asthma knowledge were measured using self-report instruments selected for their acceptability and ease of administration. Results: Twenty-five percent of the sample had possible or definite caseness for anxiety; 10.3% had possible or definite caseness for depression. Twenty-five percent had inadequate social support in some way. Three independent attitudinal factors were found: emotional maladjustment to asthma, the doctor-patient relationship, and asthma-related stigma. Level of asthma knowledge was very low. None of the measures of psychosocial function chosen were predictive of asthma knowledge. Conclusions: Levels of asthma knowledge were dangerously low, despite apparently adequate educational intiatives. In addition, patients with severe asthma have high levels of distress, particularly of anxiety, even between attacks. Their attitudes to their illness are multifactorial, and are significantly correlated with emotional distress, morbidity indices and some demographic factors. While this may point the way to interventions designed to relieve patients' distress, the hypothesis that this might in turn relate to practical asthma knowledge was not confirmed.

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Bosley, C. M., Z. M. Corden, and G. M. Cochrane. "Psychosocial factors and asthma." Respiratory Medicine 90, no. 8 (September 1996): 453–57. http://dx.doi.org/10.1016/s0954-6111(96)90170-5.

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Mathison, David A., Donald D. Stevenson, and Ronald A. Simon. "Precipitating Factors in Asthma." Chest 87, no. 1 (January 1985): 50S—54S. http://dx.doi.org/10.1378/chest.87.1.50s.

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Kamal, Khalid M., and Lesley-Ann Miller. "Psychosocial Factors and Asthma." American Journal of Respiratory and Critical Care Medicine 169, no. 11 (June 2004): 1253–54. http://dx.doi.org/10.1164/ajrccm.169.11.952.

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Tauler, E., J. Llorens-Terol, A. Mur, and C. Leal. "ASTHMA AND ENVIRONMENTAL FACTORS." Pediatric Research 19, no. 10 (October 1985): 1120. http://dx.doi.org/10.1203/00006450-198510000-00290.

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Doull, l. J. M., and S. T. Holgate. "Asthma: early predisposing factors." British Medical Bulletin 53, no. 1 (January 1, 1997): 71–80. http://dx.doi.org/10.1093/oxfordjournals.bmb.a011607.

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Giardino, Nicholas D., and Karen B. Schmaling. "Behavioral factors in asthma." Behavior Analyst Today 3, no. 2 (2002): 203–12. http://dx.doi.org/10.1037/h0099970.

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Barnes, P. J., and I. M. Adcock. "Transcription factors and asthma." European Respiratory Journal 12, no. 1 (July 1, 1998): 221–34. http://dx.doi.org/10.1183/09031936.98.12010221.

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Van Lieshout, Ryan J., and Glenda MacQueen. "Psychological Factors in Asthma." Allergy, Asthma & Clinical Immunology 4, no. 1 (2008): 12. http://dx.doi.org/10.1186/1710-1492-4-1-12.

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Lee, T. H. "Precipitating factors of asthma." British Medical Bulletin 48, no. 1 (1992): 169–78. http://dx.doi.org/10.1093/oxfordjournals.bmb.a072532.

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Rietveld, Simon, and Thomas L. Creer. "Psychiatric Factors in Asthma." American Journal of Respiratory Medicine 2, no. 1 (February 2003): 1–10. http://dx.doi.org/10.1007/bf03256634.

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Mackay, T. W., C. G. Wathen, M. F. Sudlow, R. A. Elton, and E. Caulton. "Factors Affecting Asthma Mortality in Scotland." Scottish Medical Journal 37, no. 1 (February 1992): 5–7. http://dx.doi.org/10.1177/003693309203700102.

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Asthma mortality in the age group 5 — 44 years appeared to be stable in Scotland in both males and females at a rate of approximately 1.0 per 100,000 during the period 1970 — 1988 despite an increase in the hospital discharge rate for asthma of approximately 4% per annum during that period. Two-thirds of these deaths occurred outside hospital. There was evidence of a seasonal variation in asthma deaths with a peak mortality occurring in August, four to six weeks after the peak in total pollen counts. Monthly variation in atmospheric pollution did not appear to account for the variation in asthma mortality. It is suggested that the seasonal variation in asthma mortality provides a basis for further studies to elucidate the factors contributing to these deaths.

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Ljustina-Pribic, Radmila, Slobodanka Petrovic, and Jelena Tomic. "Childhood asthma and risk factors." Medical review 63, no. 7-8 (2010): 516–21. http://dx.doi.org/10.2298/mpns1008516l.

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Introduction. This article summarizes the contribution of epidemiology to the understanding of childhood asthma. The first task in epidemiology is to determine prevalence and incidence of any disease. Prevalence. Epidemiological investigations are aimed at evaluating hypotheses about causes of disease by defining demographic characteristics of a certain population as well as by determining possible effects of environmental factors. In spite of some limitations, data obtained by epidemiological investigations have been valuable in confirming both the increasing incidence of asthma and the differences in prevalence in certain population groups. The observance of this phenomenon has led to much speculation and a lot of attempts to identify the reasons behind the rising prevalence. Risk factors. Epidemiological studies have identified risk factors for the development of childhood asthma and provided insight into natural history of disease and prognosis. Factors ranging from increased numbers of immunizations to increased air pollution have been suggested, but subsequent analysis has failed to provide the supporting evidence to implicate most of these possibilities. The concept known as the hygiene hypothesis has gained some support from epidemiological studies. Conclusion. The development of asthma as well as its severity are affected by numerous factors and their interactions can be explained by the heterogeneous nature of this disease.

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Roth, M., and J. Black. "Transcription Factors in Asthma: Are Transcription Factors a New Target for Asthma Therapy?" Current Drug Targets 7, no. 5 (May 1, 2006): 589–95. http://dx.doi.org/10.2174/138945006776818638.

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Zhong, Nanshan, Jiangtao Lin, Jinping Zheng, Kefang Lai, Canmao Xie, Ke-Jing Tang, Mao Huang, Ping Chen, and Changzheng Wang. "Uncontrolled asthma and its risk factors in adult Chinese asthma patients." Therapeutic Advances in Respiratory Disease 10, no. 6 (September 19, 2016): 507–17. http://dx.doi.org/10.1177/1753465816663978.

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Background: Asthma affects a large number of patients in China, but relatively little is known about asthma management among Chinese patients. This study aims to estimate asthma control rate among adult Chinese patients and to identify predictors associated with uncontrolled asthma. Methods: A total of 4125 asthma patients aged ⩾17 years and representing all regions of mainland China except Tibet were surveyed. Asthma control status was assessed using the Asthma Control Test (ACT) and classified as controlled (ACT score ⩾ 20) and uncontrolled (ACT score ⩽ 19). A multivariate logistic regression model was used to identify predictors associated with uncontrolled asthma from the factors including demographics, rhinitis, allergic rhinitis, and treatment adherence. Results: Asthma was controlled in 44.9%, and uncontrolled in 55.1% of the study participants. High rates of uncontrolled asthma were found in patients with treatment nonadherence (77.3%), poor adherence (66.2%), no schooling (64.8%), or obesity (62.9%). The risk of uncontrolled asthma was much higher in the treatment nonadherence group than the complete adherence group [odds ratio (OR) = 4.55 (3.68–5.62), p < 0.001]. Other predictors for uncontrolled asthma included concomitant rhinitis [OR = 1.31 (1.14–1.50), p < 0.001], obesity [OR = 1.31 (1.05–1.64), p = 0.019], asthma duration > 3 years [OR = 1.22 (1.07–1.39), p = 0.004] and age ⩾ 45 years [OR = 1.23 (1.07–1.41), p = 0.004]. Conclusions: About half of the participants in this study had uncontrolled asthma. Treatment nonadherence is one of the significant predictors, which is very strongly associated with uncontrolled asthma. Efforts should be prioritized to promote patients’ treatment adherence to improve asthma control while attention is needed on rhinitis or obesity.

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Fernandes, Silvia de Souza Campos, Dirceu Solé, Paulo Camargos, Cláudia Ribeiro de Andrade, and Cássio da Cunha Ibiapina. "Factors associated with asthma expression in adolescents." Jornal Brasileiro de Pneumologia 44, no. 1 (February 2018): 12–17. http://dx.doi.org/10.1590/s1806-37562017000000078.

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ABSTRACT Objective: To evaluate risk factors associated with asthma symptoms in adolescents in the 13- to 14-year age bracket. Methods: This was a cross-sectional study involving adolescents enrolled in randomly selected public schools in the city of Belo Horizonte, Brazil, and conducted with the use of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and its supplementary module for risk factor assessment. The ISAAC questionnaire was completed by the students themselves, whereas the supplementary questionnaire was completed by their parents or legal guardians. Variables showing p ≤ 0.25 in the univariate analysis were included in the multivariate analysis. Stepwise regression with backward elimination was used for variable selection. Results: We evaluated 375 adolescents, 124 (33.1%) of whom had asthma symptoms. The final multivariate analysis model revealed that asthma symptoms were associated with birth weight < 2,500 g (p < 0.001), day care center or nursery attendance (p < 0.002), maternal history of asthma (p < 0.001), contact with animals during the first year of life (p < 0.027), current contact with animals outside the home (dogs, cats, or farm animals; p < 0.005), and more than 20 cigarettes per day smoked by parents or other household members (p < 0.02). Conclusions: Exposure to animals in and outside the home is associated with asthma symptoms, as is environmental tobacco smoke exposure. Families, health professionals, and administrators of health care facilities should take that into account in order to prevent asthma and reduce asthma morbidity.

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Busse, William W. "Determinants of Risk Factors for Asthma." Canadian Respiratory Journal 6, no. 1 (1999): 97–101. http://dx.doi.org/10.1155/1999/285046.

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There are a number of risk factors for the development of asthma, including genetic and environmental components. Moreover, there is mounting evidence that a variety of genes are associated with the features of asthma, such as persistent wheezing, airway responsiveness and chronic bronchial inflammation. However, for expression of these features, other factors must also come into play. This paper focuses on the importance of environmental factors in the development of asthma, including allergens and respiratory infections. From current evidence, it appears that in subjects with the appropriate genetic make-up, infections and allergens induce a proinflammatory cytokine response that causes airway inflammation and that in turn leads to the initiation and persistence of altered airway function.

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Haby, M. M., J. K. Peat, G. B. Marks, A. J. Woolcock, and S. R. Leeder. "Asthma in preschool children: prevalence and risk factors." Thorax 56, no. 8 (August 1, 2001): 589–95. http://dx.doi.org/10.1136/thx.56.8.589.

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BACKGROUNDThe prevalence of asthma in children has increased in many countries over recent years. To plan effective interventions to reverse this trend we need a better understanding of the risk factors for asthma in early life. This study was undertaken to measure the prevalence of, and risk factors for, asthma in preschool children.METHODSParents of children aged 3–5 years living in two cities (Lismore, n=383; Wagga Wagga, n=591) in New South Wales, Australia were surveyed by questionnaire to ascertain the presence of asthma and various proposed risk factors for asthma in their children. Recent asthma was defined as ever having been diagnosed with asthma andhaving cough or wheeze in the last 12 monthsand having used an asthma medication in the last 12 months. Atopy was measured by skin prick tests to six common allergens.RESULTSThe prevalence of recent asthma was 22% in Lismore and 18% in Wagga Wagga. Factors which increased the risk of recent asthma were: atopy (odds ratio (OR) 2.35, 95% CI 1.49 to 3.72), having a parent with a history of asthma (OR 2.05, 95% CI 1.34 to 3.16), having had a serious respiratory infection in the first 2 years of life (OR 1.93, 95% CI 1.25 to 2.99), and a high dietary intake of polyunsaturated fats (OR 2.03, 95% CI 1.15 to 3.60). Breast feeding (OR 0.41, 95% CI 0.22 to 0.74) and having three or more older siblings (OR 0.16, 95% CI 0.04 to 0.71) decreased the risk of recent asthma.CONCLUSIONSOf the factors tested, those that have the greatest potential to be modified to reduce the risk of asthma are breast feeding and consumption of polyunsaturated fats.

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Levine;, D. A., J. L. Beausoleil, D. P. Weldon, and S. J. McGeady. "Asthma Compliance and Psychological Factors." PEDIATRICS 100, no. 4 (October 1, 1997): 731–32. http://dx.doi.org/10.1542/peds.100.4.731a.

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Benedito-Monleón, Carmen, and Juan Alonso López-Andreu. "Psychological Factors in Childhood Asthma." Behavioural and Cognitive Psychotherapy 22, no. 2 (April 1994): 153–61. http://dx.doi.org/10.1017/s1352465800011930.

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The influence of the personality of asthmatic children and their mothers on the course of their illness is analysed, taking as a basis a sample of 48 asthmatic children. This is done through the assessment of the role of personality in the change that takes place, after the application of various psychological treatments (relaxation, systematic desensitization and stress inoculation) in three variables: number of days of illness, symptomatic relief drug use and school absences. The results obtained highlight the influence of personality on therapeutic success. Consequently, this study shows the importance of tending to personality traits in order to forecast and improve the effectiveness of psychological treatment.

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Tamari, Mayumi, and Tomomitsu Hirota. "Genetic factors of childhood asthma." Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology 27, no. 4 (2013): 539–47. http://dx.doi.org/10.3388/jspaci.27.539.

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Cullinan, P., and A. J. N. Taylor. "Asthma in children: environmental factors." BMJ 308, no. 6944 (June 18, 1994): 1585–86. http://dx.doi.org/10.1136/bmj.308.6944.1585.

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ANDREW ALIGNE, C., PEGGY AUINGER, ROBERT S BYRD, and MICHAEL WEITZMAN. "Risk Factors for Pediatric Asthma." American Journal of Respiratory and Critical Care Medicine 162, no. 3 (September 2000): 873–77. http://dx.doi.org/10.1164/ajrccm.162.3.9908085.

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De Vries, Marjolein P., L. van Den Bemt, S. Lince, J. W. M. Muris, B. P. A. Thoonen, and C. P. van Schayck. "Factors Associated with Asthma Control." Journal of Asthma 42, no. 8 (January 2005): 659–65. http://dx.doi.org/10.1080/02770900500264903.

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Hall. "Genetic factors in asthma severity." Clinical & Experimental Allergy 28 (November 1998): 16–20. http://dx.doi.org/10.1046/j.1365-2222.1998.028s5016.x.

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Macri', F., F. P. Rossi, C. Lambiase, F. Bianchi di Castelbianco, and A. Frassanito. "Psychological factors in childhood asthma." Pediatric Pulmonology 43, no. 4 (February 27, 2008): 366–70. http://dx.doi.org/10.1002/ppul.20778.

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Phipatanakul, Wanda. "Environmental Factors and Childhood Asthma." Pediatric Annals 35, no. 9 (September 1, 2006): 647–56. http://dx.doi.org/10.3928/0090-4481-20060901-08.

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Terre, Lisa. "Psychosocial Factors in Pediatric Asthma." American Journal of Lifestyle Medicine 5, no. 1 (August 2, 2010): 40–43. http://dx.doi.org/10.1177/1559827610377397.

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Cullinan, Paul, and Anthony Newman Taylor. "Asthma: environmental and occupational factors." British Medical Bulletin 68, no. 1 (December 1, 2003): 227–42. http://dx.doi.org/10.1093/bmb/ldg021.

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Stern, Jessica, Jennifer Pier, and Augusto A. Litonjua. "Asthma epidemiology and risk factors." Seminars in Immunopathology 42, no. 1 (February 2020): 5–15. http://dx.doi.org/10.1007/s00281-020-00785-1.

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Singh, Rajesh Kumar, Rajeev Kumar Thapar, Rakesh Kumar Gupta, and Abhijit YV. "Factors Affecting Drug Compliance in Paediatric Asthma." Journal of Nepal Paediatric Society 37, no. 1 (October 4, 2017): 31–35. http://dx.doi.org/10.3126/jnps.v37i1.17201.

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Introduction: Childhood asthma is an immensely important chronic disease in children with increasing prevalence worldwide. Inhaled corticosteroids and bronchodilators are the key drugs in asthma therapy.Material and Methods: Compliance of childhood asthma was assessed at a tertiary care centre to find out the percentage of compliant Vs noncompliant patients and the reasons for the latter. If the patient had attended at least nine visits (> 75%) the previous year he was labelled compliant and those with less than six visits (<50%) were put in the non-complaint group.Results: Of the 374 patients attending the asthma clinic, 60 were randomly selected for the study of which 53 finally participated. In this study the compliance was 47% and gender predilection did not affect compliance. The distance a patient had to commute to reach the hospital and the mother’s education did not have any influence on the compliance. Older asthmatics exhibited better compliance in our study.Conclusion: Forty percent of our patients were compliant to regular use of prescribed medicine. Older age of the patients and care giver`s awareness about asthma were the two factors which are statistically significant in compliance with drug therapy in asthma. Gender of the patient, academic qualification and distance from the hospital did not have a significant effect on compliance.

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Jobin, Marie-Sophie, Jocelyne Moisan, Yves Bolduc, Eileen Dorval, Louis-Philippe Boulet, and Jean-Pierre Grégoire. "Factors Associated with the Appropriate Use of Asthma Drugs." Canadian Respiratory Journal 18, no. 2 (2011): 97–104. http://dx.doi.org/10.1155/2011/426528.

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BACKGROUND: When used properly, asthma drugs can reduce asthma-related morbidity and mortality.OBJECTIVE: To assess the use of asthma drugs, and to identify factors associated with appropriateness of use among patients 12 to 45 years of age.METHODS: Asthmatic patients were interviewed about their asthma drug(s) use and the factors potentially associated with appropriateness of use according to the 2003 Canadian Asthma Consensus Conference guidelines. To determine the factors associated with the appropriate use of asthma drugs, a multivariate logistic regression model was built using a stepwise procedure, and ORs and associated 95% CIs were calculated.RESULTS: Of the 349 study participants, 43 (12.3%) reported appropriate use of their asthma drugs. Respondents who were more likely to report appropriate use were patients with sound knowledge of their asthma drugs (OR 2.61 [95% CI 1.29 to 5.29]), those in good, very good or excellent self-perceived health (OR 3.37 [95% CI 1.31 to 8.71]), those who had consulted a specialist during the preceding year (OR 2.28 [95% CI 1.05 to 4.97]) and those who declared themselves short of drugs due to a lack of money (OR 2.78 [95% CI 1.26 to 6.17]).CONCLUSIONS: Results of the present study suggested that recommendations in the current guidelines regarding the appropriate use of asthma medications are being poorly implemented. Educational interventions with the aim of improving quality of care and knowledge about asthma drugs should be offered.

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Stempel, D. A., P. Dorinsky, S. Yancey, A. Emmett, and K. Rickard. "Risk factors for asthma exacerbations: Is asthma severity a predictor?" Journal of Allergy and Clinical Immunology 111, no. 2 (February 2003): S135. http://dx.doi.org/10.1016/s0091-6749(03)80422-0.

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Albataineh, Eman, Enas Al-Zayadneh, Hani Al-Shagahin, Ahlam AL Soloman, Areej Altarawneh, and Ibrahim Aldmour. "Asthma Control and Its Predictive Factors in Adult Asthma Patients." Journal of Clinical Medicine Research 11, no. 12 (2019): 807–17. http://dx.doi.org/10.14740/jocmr4021.

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Fernandes, Andréia Guedes Oliva, Carolina Souza-Machado, Renata Conceição Pereira Coelho, Priscila Abreu Franco, Renata Miranda Esquivel, Adelmir Souza-Machado, and Álvaro Augusto Cruz. "Risk factors for death in patients with severe asthma." Jornal Brasileiro de Pneumologia 40, no. 4 (August 2014): 364–72. http://dx.doi.org/10.1590/s1806-37132014000400003.

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OBJECTIVE: To identify risk factors for death among patients with severe asthma. METHODS: This was a nested case-control study. Among the patients with severe asthma treated between December of 2002 and December of 2010 at the Central Referral Outpatient Clinic of the Bahia State Asthma Control Program, in the city of Salvador, Brazil, we selected all those who died, as well as selecting other patients with severe asthma to be used as controls (at a ratio of 1:4). Data were collected from the medical charts of the patients, home visit reports, and death certificates. RESULTS: We selected 58 cases of deaths and 232 control cases. Most of the deaths were attributed to respiratory causes and occurred within a health care facility. Advanced age, unemployment, rhinitis, symptoms of gastroesophageal reflux disease, long-standing asthma, and persistent airflow obstruction were common features in both groups. Multivariate analysis showed that male gender, FEV1 pre-bronchodilator < 60% of predicted, and the lack of control of asthma symptoms were significantly and independently associated with mortality in this sample of patients with severe asthma. CONCLUSIONS: In this cohort of outpatients with severe asthma, the deaths occurred predominantly due to respiratory causes and within a health care facility. Lack of asthma control and male gender were risk factors for mortality.

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Osman, Rashid, Khalid Ahmed, and Asma ElSony. "Factors associated with uncontrolled asthma among Sudanese adult patients." Journal of the Pan African Thoracic Society 2 (May 25, 2021): 85–93. http://dx.doi.org/10.25259/jpats_22_2020.

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Objectives: Uncontrolled asthma is a major health problem resulting in increased morbidity, mortality, healthcare utilization, and costs. The aim of this study was to determine the level of asthma control and its associated factors in Sudan. Materials and Methods: We performed a cross-sectional study of 362 adult asthmatics consecutively recruited from the three main tertiary hospitals in Khartoum State-Sudan, between March and June 2018. Data were collected using standardized questionnaires and the asthma control test (ACT) was used to determine the level of control. Logistic regression analysis was used to determine factors associated with uncontrolled asthma. Results: The mean age of the subjects was 40.1 years (SD 15.7) and the sex distribution was almost equal, with 195 (53.9%) females. Among all asthmatics, the prevalence of uncontrolled asthma was 84.5%, according to ACT score. Factors associated with uncontrolled asthma included; health facility (odd ratios [OR] = 2.96 [1.27–6.86]), time to reach facility (OR = 4.51 [1.68–12.06]), non-adherence to follow-up visits (OR = 5.11 [1.12–23.36]), steroids tablets use without prescription (OR = 9.01 [1.01–79.88]), family history of asthma (OR = 0.45 [0.21– 0.95]), and inhaler technique training (OR = 0.37 [0.17–0.78]). Conclusion: This study showed a high rate of uncontrolled asthma in three tertiary hospitals in Khartoum. Factors associated with uncontrolled asthma may be considered as targets for future intervention strategies.

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Ilmarinen, Pinja, Leena E. Tuomisto, and Hannu Kankaanranta. "Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma." Mediators of Inflammation 2015 (2015): 1–19. http://dx.doi.org/10.1155/2015/514868.

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Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an important factor in separating the phenotypes. Genetic factors, atopy, and early respiratory tract infections are well-recognized factors predisposing to childhood-onset asthma. Adult-onset asthma is more often associated with obesity, smoking, depression, or other life-style or environmental factors, even though genetic factors and respiratory tract infections may also play a role in adult-onset disease. Adult-onset asthma is characterized by absence of atopy and is often severe requiring treatment with high dose of inhaled and/or oral steroids. Variety of risk factors and nonatopic nature of adult-onset disease suggest that variety of mechanisms is involved in the disease pathogenesis and that these mechanisms differ from the pathobiology of childhood-onset asthma with prevailing Th2 airway inflammation. Recognition of the mechanisms and mediators that drive the adult-onset disease helps to develop novel strategies for the treatment. The aim of this review was to summarize the current knowledge on the pathogenesis of adult-onset asthma and to concentrate on the mechanisms and mediators involved in establishing adult-onset asthma in response to specific risk factors. We also discuss the involvement of these mechanisms in the currently recognized phenotypes of adult-onset asthma.

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Assis, Elisangela Vilar de, Milana D. R. Santana, Ankilma Do N. A. Feitosa, Milena N. Alves de Sousa, Ubiraídys De A. Isidório, Vitor E. Valenti, and Fernando Luiz Affonso Fonseca. "Prevalence of Asthma symptoms and risk factors in adolescents." Journal of Human Growth and Development 29, no. 1 (May 6, 2019): 110–16. http://dx.doi.org/10.7322/jhgd.157758.

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Introduction: Asthma is a chronic disease of the airways, which is increasing its prevalence among teenagers recently. The trigger-related factors are numerous, including environmental factors, genetic, food among others. Objective: Investigate the prevalence of asthma symptoms and possible risk factors in adolescents. Methods: This is a cross-sectional, descriptive and quantitative study conducted in 104 adolescents aged between 13 to 14 years old of both sexes from four educational institutions: three private and one public. Participants answered two questionnaires: one on risk factors for allergic diseases (EISL) and the other on asthma symptoms (ISAAC asthma module). Results: 104 adolescents answered the questionnaire: 54.8% girls and 45.2% boys. Male subjects had the most active asthma (64%) than female (20%) (p = 0.01) and also had more physician-diagnosed asthma (34.4%) than girls (6.1%) (p = 0.04), more wheezing after exercise (34.4%; 12.1%) (p = 0.03). Regarding the association between the symptoms and the risk factors we observed a statistically significant relationship between the presence of wheezing and hospitalization for public schools girls (p = 0.05). Conclusion: There is a higher prevalence of asthma symptoms in males than in females unlike other studies was observed.

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Tough, SC, PA Hessel, FHY Green, I. Mitchell, S. Rose, H. Aronson, and JC Butt. "Factors that Influence Emergency Department Visits for Asthma." Canadian Respiratory Journal 6, no. 5 (1999): 429–35. http://dx.doi.org/10.1155/1999/743628.

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BACKGROUND: Asthma can usually be controlled through allergen avoidance and/or appropriate medication. An emergency department visit for an acute exacerbation of asthma often represents a breakdown in asthma management. Emergency department treatment results in significant health care expenditures and reflects a compromised quality of life.OBJECTIVES: To identify risk factors associated with an emergency department visit for asthma.METHODS: This case-control study compared 299 people (76% of 390 cases contacted) who attended one of two emergency departments in Alberta in 1992 and 1993 for an acute exacerbation of asthma (cases) with 212 unmatched community controls with asthma who were located by random digit dialing. Cases and controls were asked to complete a mailed questionnaire to obtain data regarding severity, visits to doctors and emergency departments, medication use, allergies and other triggers, and smoking history. Data analysis included bivariate analysis of risk factors and multivariate model development using logistic regression.RESULTS: The response rate was similar between cases and controls. Cases were younger than controls (odds ratio [OR] 2.16, 95% CI 1.34 to 3.48) and more often reported their asthma to be severe (OR 4.25, 95% CI 2.24 to 8.06), and had experienced nocturnal symptoms (stratified OR range 1.36 to 6.82). Cases used more health care services in the previous year, had been admitted to hospital at some time for asthma (OR 1.62, 95% CI 1.10 to 2.38) and used more medication than controls.CONCLUSIONS: Physicians and other health care workers should be sensitive to the risk factors and target interventions to high risk individuals.

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Korvyakov, S. A. "Influence of infectious factors on asthma course." PULMONOLOGIYA, no. 5 (October 28, 2007): 33–39. http://dx.doi.org/10.18093/0869-0189-2007-0-5-33-39.

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Microbial contamination of airways is of great interest due to its influence on bronchial asthma (BA) course. The aim of this study was to investigate sputum and colonic microflora in BA patients, influence of dysbiosis on BA course and to find ways for its correction. The study involved 108 BA patients (84 females, 24 males), 15 to 60 years of age, divided into 2 groups: 69 patients with good clinical effect of standard asthma therapy and 40 patients without clinical improvement after 2-wk standard therapy (torpid BA course). The patients have been observed for a year. We evaluated rate and severity of BA exacerbations, sputum and colonic flora. An original questionnaire has been developed to assess main asthma features and their influence of the patient's status. Pathogenic or conditional-pathogenic flora presented in associations with fungi in 85 % was yielded in all the patients with torpid BA course. Antimicrobial and antifungal medications allowed improved asthma control in 82 % and eradication of airway pathogens in 70 % of the patients. Colonic dysbiosis was found in 94.9 % of BA patients. Its correction resulted in better BA control. This effect have maintained for 3 to 5 months after probiotic therapy was finished. Thereafter these patients required repeated bacteriological monitoring and treatment.

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Lawson, Joshua A., Donna C. Rennie, Ambikaipakan Senthilselvan, Donald W. Cockcroft, and Helen H. McDuffie. "Regional Variations in Risk Factors for Asthma in School Children." Canadian Respiratory Journal 12, no. 6 (2005): 321–26. http://dx.doi.org/10.1155/2005/942637.

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BACKGROUND: The authors have previously reported an increased prevalence of asthma in Estevan, Saskatchewan (21.4%) compared with Swift Current, Saskatchewan (16.2%).OBJECTIVE: To determine the association between asthma and personal and indoor environmental risk factors in these communities.METHODS: A population-based cross-sectional study was conducted in January 2000. A questionnaire was distributed to school children in grades 1 to 6 for completion by a parent. Multivariate logistic regression was used to examine associations between various risk factors and physician-diagnosed asthma.RESULTS: Asthma was associated with respiratory allergy (adjusted OR [adjOR]=8.85, 95% CI 6.79 to 11.54), early respiratory illness (adjOR=2.81, 95% CI 1.96 to 4.03) and family history of asthma (adjOR=2.37, 95% CI 1.67 to 3.36). Several environmental factors varied with asthma by town. In Estevan, asthma was associated with home mould or dampness (adjOR=1.82, 95% CI 1.23 to 2.69) and was inversely associated with air conditioning (adjOR=0.56, 95% CI 0.37 to 0.85). The risk of asthma was increased if the child had previous exposure to environmental tobacco smoke from the mother in both communities (Swift Current: OR=1.87, 95% CI 1.06 to 3.30; Estevan: OR=2.00, 95% CI 1.17 to 3.43), and there was an inverse association with current exposure to environmental tobacco smoke from the mother in Estevan (OR=0.64, 95% CI 0.40 to 1.00). When multivariate analyses were stratified by sex, the relationship between home mould or dampness and asthma was most prominent in girls in Estevan.CONCLUSIONS: Despite a similar regional location, different risk factors for asthma were identified in each community. Local environmental factors are important to consider when interpreting findings and planning asthma care.

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Folz, Rodney. "ASTHMA IN OLDER ADULTS: IDENTIFYING PHENOTYPES AND FACTORS IMPACTING OUTCOMES." Innovation in Aging 3, Supplement_1 (November 2019): S13. http://dx.doi.org/10.1093/geroni/igz038.045.

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Abstract Asthma, of all chronic diseases, has the highest disease burden attributed to environmental exposures. Few studies have attempted to characterize the prevalence of co-existing auto-inflammatory disease and asthma, or to link environmental exposure as a factor that may increase asthmatic lung obstruction and racial disparity with auto-inflammatory comorbidity. While there is an increased risk for asthma development and severity linked to certain autoimmune diseases, there is a known racial disparity in the prevalence of these autoimmune diseases. Racial and ethnic differences in the link between environmental exposures and auto-immune comorbid asthma as a potential common trigger of inflammation is not well understood. This talk will focus on developing a model to longitudinally predict asthma control and quality of life associated with home environmental triggers and volatile organic chemical (VOC) exposure in older adults and investigate the direct and indirect effect of autoimmune disease in racial disparities of the longitudinal relationships of home environmental asthma triggers on airway obstruction and functional status in older adults with asthma.

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Gaimolenko, I. N., and N. L. Potapova. "Risk factors for bronchial asthma in children in Chita Region." Bulletin of Siberian Medicine 6, no. 4 (December 30, 2007): 112–16. http://dx.doi.org/10.20538/1682-0363-2007-4-112-116.

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Risk factors for bronchial asthma in children of Chita Region were studied. According to the literature data, 12 clinical-anamnestic characteristics were suggested to be risk factors for bronchial asthma. Prevalence of risk factors was assessed in 72 children with severe asthma, 60 children with moderate, and 58 children with mild bronchial asthma. Odds ratios (OR) with the 95% confident interval for each factor were calculated. Factors with predominance in the asthma group included: parental history of asthma (OR = 16.2), congenital abnormalities and complications of pregnancy and labor (OR = 1.9), prenatal lesion of central nervous system (OR = 2.8), recurrent respiratory tract infections (OR = 12.4), coexisting atopic dermatitis (OR = 1.8), passive smoking (OR = 2.8), and food sensitization (OR = 7.7). The findings can be used to calculate individual risks in a population for prediction of development of this pathology and for its timely prevention.

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Meijer, Anne Marie, Rupino W. Griffioen, Jan C. van Nierop, and Louis Oppenheimer. "Intractable or Uncontrolled Asthma: Psychosocial Factors." Journal of Asthma 32, no. 4 (January 1995): 265–74. http://dx.doi.org/10.3109/02770909509044834.

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Vandenplas, Olivier. "Occupational Asthma: Etiologies and Risk Factors." Allergy, Asthma and Immunology Research 3, no. 3 (2011): 157. http://dx.doi.org/10.4168/aair.2011.3.3.157.

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Choi, Inseon S., Won-Joo Ki, Tae-Ock Kim, Eui-Ryoung Han, and Il-Kook Seo. "Seasonal Factors Influencing Exercise-Induced Asthma." Allergy, Asthma & Immunology Research 4, no. 4 (2012): 192. http://dx.doi.org/10.4168/aair.2012.4.4.192.

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&NA;. "Risk factors for adult asthma identified." Inpharma Weekly &NA;, no. 946 (July 1994): 12. http://dx.doi.org/10.2165/00128413-199409460-00024.

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Macarthur, Colin, Caroline Calpin, Patricia C. Parkin, and William Feldman. "Factors associated with pediatric asthma readmissions." Journal of Allergy and Clinical Immunology 98, no. 5 (November 1996): 992–93. http://dx.doi.org/10.1016/s0091-6749(96)80017-0.

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Kuruvilla, Merin E., Kristine Vanijcharoenkarn, Jennifer A. Shih, and Frances Eun-Hyung Lee. "Epidemiology and risk factors for asthma." Respiratory Medicine 149 (March 2019): 16–22. http://dx.doi.org/10.1016/j.rmed.2019.01.014.

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Journal articles on the topic 'Factors and asthma'

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