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1

Beer, Tomasz M. Cancer clinical trials: A commonsense guide to experimental cancer therapies and clinical trials. New York: DiaMedica Pub., 2012.

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2

Finn, Robert. Cancer clinical trials: Experimental treatments & how they can help you. Beijing: O'Reilly, 1999.

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3

Cancer clinical trials: Experimental treatments & how they can help you. Beijing: O'Reilly, 1999.

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4

Patel, Shilpesh S. Handbook of cardiovascular clinical trials. New York, NY: Churchill Livingstone, 1997.

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5

Rothmann, Mark D. Design and analysis of non-inferiority trials. Boca Raton: Chapman & Hall/CRC, 2011.

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6

Williams, E. R. Experimental design and analysis for use in tree improvement. East Melbourne, Vic: CSIRO, 1994.

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7

Griffin, J. P. The textbook of pharmaceutical medicine. 6th ed. Chichester, West Sussex: Wiley-Blackwell, 2009.

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8

Mark, Chang, ed. Adaptive design methods in clinical trails. Boca Raton, FL: Chapman & Hall/CRC, 2007.

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9

National Research Council (U.S.). Committee on National Statistics and National Academies Press (U.S.), eds. The prevention and treatment of missing data in clinical trials. Washington, D.C: National Academies Press, 2010.

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10

Clinical research and the law. Chichester, West Sussex: John Wiley & Sons, 2012.

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11

Adequacy of access to investigative drugs for seriously ill patients: Hearing before the Subcommittee on Oversight and Investigations of the Committee on Commerce, House of Representatives, One Hundred Fifth Congress, first session, September 23, 1997. Washington: U.S. G.P.O., 1997.

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12

Uncontrolled: The surprising payoff of trial-and-error for business, politics, and society. New York: Basic Books, 2012.

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13

Hill, David E. Specialty melon trials. New Haven: Connecticut Agricultural Experiment Station, 1995.

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14

Youngen, John A. Jerusalem artichoke trials in Southern Oregon. [Corvallis, Or.]: Agricultural Experiment Station, Oregon State University, 1992.

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15

G, Gauch Hugh. Statistical analysis of regional yield trials: AMMI analysis of factorial designs. Amsterdam: Elsevier, 1992.

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16

Schechter, Martin T. Open arms and alternative clinical trial designs : report =: Essais à option libre et autres plans d'essais cliniques : rapport. Ottawa, Ont: Health and Welfare Canada = Santé et bien-être social Canada, 1990.

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17

Rosselló, J. M. Elena. Technical guidelines for field variety trials. Rome: Food and Agriculture Organization of the United Nations, 1993.

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18

J. G. P. W. Clevers. Application of remote sensing to agricultural field trials. The Netherlands: Agricultural University Wageningen, 1986.

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19

Briscoe, C. Buford. Field trials manual for multipurpose tree species. 2nd ed. Arlington, VA, USA: Winrock International Institute for Agricultural Development, 1990.

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20

Briscoe, C. B. Field trials manual for multipurpose tree species. Edited by Adams Norma 1953-. Arlington, VA, USA: Winrock International Institute for Agricultural Development, 1989.

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21

Otsamo, Riikka. Updated trial descriptions and trial histories in Bura in 1984-1993. Nairobi, Kenya: Kenya Forestry Research Institute, 1993.

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22

Kaarakka, Vesa. Updated trial descriptions and trial histories in Bura in 1984-1991. Nairobi, Kenya: Kenya Forestry Research Institute, 1991.

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23

Werner, Müller Hans. Field trials with agrominerals in Malawi. Zomba [Malawi]: Republic of Malawi, Ministry of Forestry and Natural Resources, Geological Survey Dept., 1992.

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24

United States. Congress. House. Committee on Small Business. Subcommittee on Regulation, Business Opportunities, and Technology. Problems in securing informed consent of subjects in experimental trials of unapproved drugs and devices: Hearing before the Subcommittee on Regulation, Business Opportunities, and Technology of the Committee on Small Business, House of Representatives, One Hundred Third Congress, second session, Washington, DC, May 23, 1994. Washington: U.S. G.P.O., 1994.

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25

United, States Congress House Committee on Small Business Subcommittee on Regulation Business Opportunities and Technology. Problems in securing informed consent of subjects in experimental trials of unapproved drugs and devices: Hearing before the Subcommittee on Regulation, Business Opportunities, and Technology of the Committee on Small Business, House of Representatives, One Hundred Third Congress, second session, Washington, DC, May 23, 1994. Washington: U.S. G.P.O., 1994.

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26

Holding, Christine. On-farm diagnostic trials in Gilgil and Kinangop Divisions. [Nairobi] Kenya: FINNIDA in cooperation with the Ministry of Environment and Natural Resources, Forest Dept., 1995.

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27

Judd, J. Hewitt. United States pattern coins, experimental, and trial pieces: America's rarest coins. 8th ed. Atlanta, Ga: Whitman Pub., 2003.

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28

Equatoria Region Agricultural Programme. Agronomy Section. Summary of trial results - 1986, and proposed experimental programme for 1988. Finchampstead: MASDAR (UK) Ltd., 1987.

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29

Tober, Dwight A. Sideoats grama (Bouteloua curtipendula), performance trials: North Dakota, South Dakota, and Minnesota. Bismark, ND: USDA, Natural Resources Conservation Service, 2010.

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30

Brewbaker, James L. The MIR (Maize inbred resistance) trials: Performance of tropical-adapted maize inbreds. Honolulu, Hawaii: HITAHR, College of Tropical Agriculture and Human Resources, University of Hawaii, 1989.

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31

Spilker, Bert. Data collection forms in clinical trials. New York: Raven Press, 1991.

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32

Youngberg, Harold Wayne. Oregon forage and turf grass variety seed trial, 1982-83. Corvallis, Or: Agricultural Experiment Station, Oregon State University, 1985.

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33

1933-, Poey Federico, ed. On-farm agronomic trials in farming systems research and extension. Boulder, Colo: L. Rienner, 1985.

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34

Borowsky, Beth, and Cristina Sampaio. Experimental Therapeutics. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199929146.003.0017.

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Bringing safe and effective treatments to patients with Huntington’s disease (HD) will require evaluation in properly designed and conducted clinical trials. Such clinical trials will require appropriate tools and practices, including therapeutics, patient registries, biomarkers, endpoints, trial design, and analysis tools. This chapter provides insight into the advances being made in each of these areas and highlights the challenges remaining. Lessons learned from prior HD trials as well as from trials in other neurodegenerative diseases affect our view of future HD clinical development. With much interest from both pharmaceutical companies and academic researchers, this final chapter of the book actually opens a new chapter in the history of HD drug development.
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35

Ogden, Timothy N. Experimental Conversations: Perspectives on Randomized Trials in Development Economics. MIT Press, 2017.

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36

Banerjee, Abhijit V. Experimental Conversations: Perspectives on Randomized Trials in Development Economics. MIT Press, 2017.

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37

Experimental conversations: Perspectives on randomized trials in development economics. The MIT Press, 2016.

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38

Banerjee, Abhijit V. Experimental Conversations: Perspectives on Randomized Trials in Development Economics. MIT Press, 2017.

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39

Chang, Mark, and Shein-Chung Chow. Adaptive Design Methods in Clinical Trials (Biostatistics). Chapman & Hall/CRC, 2006.

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40

Shannon, William, Daniel P. Schuster, William J. Powers, Mario Castro, and Jeffrey E. Saffitz. Translational and Experimental Clinical Research. Lippincott Williams & Wilkins, 2005.

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41

P, Schuster Daniel, and Powers William J. MD, eds. Translational and experimental clinical research. Philadelphia: Lippincott Williams & Wilkins, 2005.

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42

Hallberg, Kelly, Coady Wing, Vivian Wong, and Thomas D. Cook. Experimental Design for Causal Inference: Clinical Trials and Regression Discontinuity Designs. Oxford University Press, 2013. http://dx.doi.org/10.1093/oxfordhb/9780199934874.013.0012.

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43

Rothmann, Mark D., Brian L. Wiens, and Ivan S. F. Chan. Design and Analysis of Non-Inferiority Trials. Taylor & Francis Group, 2016.

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44

Rothmann, Mark D., Brian L. Wiens, and Ivan S. F. Chan. Design and Analysis of Non-Inferiority Trials. Taylor & Francis Group, 2020.

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45

Robb, Sheri L., and Debra S. Burns. Randomized Controlled Trials in Music Therapy. Edited by Jane Edwards. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199639755.013.14.

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Randomized controlled trials (RCTs) are experiments that compare two or more groups of participants, and participants are assigned to groups based on chance. Groups include an experimental intervention group that is being compared to a treatment as usual, a low dose or attention control condition, and/or a comparative treatment group. The purpose of randomization is to equalize groups on both known and unknown characteristics that may influence the outcome and the effectiveness of the intervention. This chapter describes how music therapists have used RCTs to demonstrate the effectiveness of music therapy interventions and services. Key strategies for implementing RCT designs are presented, and studies in music therapy that have used this design are reviewed.
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46

Hershberger, Scott L. Multivariate Clinical Trials For Randomized Experiments In The Behavioral Sciences. Psychology Press, 2011.

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47

Miksza, Peter, and Kenneth Elpus. Design and Analysis of Experimental Research I. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199391905.003.0008.

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This chapter builds on the previous chapter by elaborating from theories of causal knowledge presented earlier to practical considerations for the design, execution, and analysis of randomized experiments and randomized controlled trials in music education research. The straightforward statistical analysis of the two-group experimental designs is explained through the t test. The analysis of variance technique is explained for the analysis of experimental and quasi-experimental data involving more than two groups. The chapter closes with a discussion of the analysis of data arising from experiments where additional data, beyond group membership and the score on an outcome measure, is known about the participants (i.e., analysis of covariance).
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48

Design and Analysis of Non-Inferiority Trials (Biostatistics). Chapman & Hall/CRC, 2009.

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49

Vanderschueren, S. Thrombolytic Properties of Recombinant Staphylokinase in Experimental Animal Models in Clinical Trials. Leuven University Press, 1996.

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50

Trials Of Arab Modernity Literary Affects And The New Political. Fordham University Press, 2013.

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