Academic literature on the topic 'Exhaled nitric oxide'

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Journal articles on the topic "Exhaled nitric oxide"

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Smith, Andrew D., Jan O. Cowan, Karen P. Brassett, Sue Filsell, Chris McLachlan, Gabrielle Monti-Sheehan, G. Peter Herbison, and D. Robin Taylor. "Exhaled Nitric Oxide." American Journal of Respiratory and Critical Care Medicine 172, no. 4 (August 15, 2005): 453–59. http://dx.doi.org/10.1164/rccm.200411-1498oc.

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Taylor, D. Robin. "Exhaled Nitric Oxide." American Journal of Respiratory and Critical Care Medicine 179, no. 2 (January 15, 2009): 88–89. http://dx.doi.org/10.1164/rccm.200810-1605ed.

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Kharitonov, Sergei A., and Peter J. Barnes. "Exhaled nitric oxide." Current Opinion in Anaesthesiology 9, no. 6 (December 1996): 542–48. http://dx.doi.org/10.1097/00001503-199609060-00017.

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Kharitonov, Sergei A., and Peter J. Barnes. "Exhaled nitric oxide." Current Opinion in Anaesthesiology 9, no. 6 (December 1996): 542–48. http://dx.doi.org/10.1097/00001503-199612000-00017.

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Stempel, David A. "EXHALED NITRIC OXIDE." Annals of Allergy, Asthma & Immunology 92, no. 3 (March 2004): 381. http://dx.doi.org/10.1016/s1081-1206(10)61581-5.

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Leung, Donald Y. M., Harold S. Nelson, Stanley J. Szefler, and William W. Busse. "Exhaled nitric oxide." Journal of Allergy and Clinical Immunology 112, no. 5 (November 2003): 817. http://dx.doi.org/10.1016/j.jaci.2003.09.004.

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Stewart, Lora, and Rohit Katial. "Exhaled Nitric Oxide." Immunology and Allergy Clinics of North America 27, no. 4 (November 2007): 571–86. http://dx.doi.org/10.1016/j.iac.2007.09.002.

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Stewart, Lora, and Rohit K. Katial. "Exhaled Nitric Oxide." Immunology and Allergy Clinics of North America 32, no. 3 (August 2012): 347–62. http://dx.doi.org/10.1016/j.iac.2012.06.005.

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Hoyte, Flavia C. L., Lara M. Gross, and Rohit K. Katial. "Exhaled Nitric Oxide." Immunology and Allergy Clinics of North America 38, no. 4 (November 2018): 573–85. http://dx.doi.org/10.1016/j.iac.2018.06.001.

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Fazel, Fatimah. "Exhaled Nitric Oxide Measurement." Journal of Asthma & Allergy Educators 2, no. 2 (April 2011): 99–100. http://dx.doi.org/10.1177/2150129711404414.

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Dissertations / Theses on the topic "Exhaled nitric oxide"

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Kharitonov, Sergei Alexandrovich. "Exhaled nitric oxide in airway diseases." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266411.

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Hemmingsson, Tryggve. "Exhaled nitric oxide in extreme environments." Stockholm : Karolinska institutet, 2009. http://diss.kib.ki.se/2009/978-91-7409-609-5/.

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Liu, Jia Clinical School Prince of Wales Hospital Faculty of Medicine UNSW. "Nitric oxide in airway inflammation." Publisher:University of New South Wales. Clinical School - Prince of Wales Hospital, 2009. http://handle.unsw.edu.au/1959.4/43678.

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Exhaled breath condensate (EBC) is a non-invasive method of investigating airway inflammation associated with nitric oxide (NO) and the metabolites nitrite/nitrates (NOx) in diseases such as chronic obstructive pulmonary disease (COPD), but some of the variables affecting the results are unknown. It was hypothesised that 1) EBC would be influenced by lung volumes and the type of EBC collection device; 2) fractional exhaled NO (FENO) and EBC NOx in COPD patients would be altered by smoking and glucocorticosteroids (GCS); 3) cigarette smoke could contribute to the EBC NOx concentration while it may also decrease FENO indirectly by converting airway NO to NOx. It was found that EBC volume was significantly correlated with both tidal volume and minute volume. Comparing four EBC collection devices demonstrated greater efficiency with the ECoScreen?? than siliconised glass tubes or RTube?? but it gave factitiously high NOx levels. Total EBC protein levels over a 10-minute collection were significantly higher using the ECoScreen?? than either glass or RTube?? devices. A cross-sectional study of 96 COPD patients and 80 age-matched control subjects demonstrated that FENO levels in COPD patients were significantly higher than normal subjects when comparing either the combined groups or appropriate two subgroups: ex-smokers and smokers. GCS treatment demonstrated no significant effect on either FENO levels or EBC NOx, but EBC NOx was elevated in smokers. In vitro, cigarette smoke extract (CSE) induced significantly higher NOx and asymmetric dimethylarginine (ADMA) levels in A549 cells when compared with control media. The anti-oxidant, NAC pre-treatment partially reversed the elevated NOx levels but not the ADMA levels. This thesis is the first to report FENO and EBC NOx in COPD patients in an appropriate sample size to be able to evaluate each subgroup, and the increased EBC NOx levels found in smokers in vivo was consistent with the elevated NOx level in response to CSE observed in vitro. These data indicate that smoking-related airway inflammation and activation of the NO pathway are complex with both an increase in ADMA, NO, NOx and may be regulated by oxidative stress rather than the nitric oxide synthase (NOS) pathway.
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Ratnawati, Ratnawati Prince of Wale Hospital Clinical School UNSW. "Exhaled nitric oxide in asthmatic airway inflammation." Awarded by:University of New South Wales. Prince of Wale Hospital Clinical School, 2006. http://handle.unsw.edu.au/1959.4/25729.

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Measuring the level of exhaled NO (eNO) in the breath is a new method to monitor airway inflammation in asthma and may have a role in the management of asthma. The hypotheses were that eNO will reflect the degree of inflammation in chronic asthma, and will indicate how anti- inflammatory therapy should be altered to improve asthma control. Three studies were performed to test the hypotheses. A cross sectional study was performed to define the normal range of eNO and to compare this range with those who have asthma or atopy. The second study was observational, to compare the level of eNO during and after an exacerbation of asthma. The third study was an interventional study to evaluate eNO in management of paediatric asthma. In this latter study the level of eNO was measured to monitor airway inflammation in asthmatic children with the intention of adjusting antiinflammatory drugs (inhaled glucocorticosteroids) according to the level of eNO. These studies have shown that the mean level of eNO was significantly higher in asthmatic compared with normal subjects, but not significantly different when compared with atopic non-asthmatic subjects. eNO was correlated with the number of positive skin prick tests in atopic subjects whether asthmatic or nonasthmatic. The eNO level was increased during acute exacerbations of asthma and decreased after two weeks with therapy of GCS. In a pilot study eNO appeared to be superior to FEV1 in adjusting the dose of iGCS to control asthmatic children, but this needs to be confirmed with a larger sample size. Another non-invasive method to detect inflammatory markers is the technique of exhaled breath condensate (EBC). Although NO is degraded to NOx, it was found that eNO had no significant correlation with EBC NOx but had a significant correlation with pH. Hypertonic saline challenge, an artificial model of an asthmatic exacerbation was associated with an increase in EBC volume and the release of histamine, implicating mast cell activation. These novel findings suggest that non-invasive markers can be used both for clinical and mechanistic proposes.
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Pedroletti, Christophe. "Exhaled nitric oxide in schoolchildren with asthma /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-164-4/.

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Marteus, Helena. "Oropharyngeal origin of markers in exhaled breath /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-274-8/.

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Mitchell, Colin. "The Association Between Exhaled Nitric Oxide in Exhaled Breath Condensate and Chronic Obstructive Pulmonary Disease." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/397.

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Chronic obstructive pulmonary disease (COPD), a progressive and nonreversible disease, is a leading cause of mortality and morbidity throughout the world. Detecting COPD early in the disease process will help in decreasing later stage COPD severity. Because airway inflammation is a hallmark of COPD, it has been proposed that measuring exhaled nitric oxide, a marker of inflammation, in exhaled breath condensate could prove to be an inexpensive and efficient method to detect COPD in outpatient settings. Using the hypothetico-deductive theory as a guideline, this study used secondary data from the National Health and Nutrition Examination Survey 2007 to 2010 to test the association between exhaled nitric oxide (eNO), COPD, and COPD severity. In addition, this study explored whether occupation modifies the association between eNO and COPD. Descriptive statistics, chi-square analyses, and regression analyses were used to analyze data from a sample size of 10,214 individuals. The prevalence of COPD was 7.2%, based on self-reported physician diagnoses and 11.4% based on prebronchodilator spirometry analysis, strengthening the argument that COPD is often under- or misdiagnosed in clinical settings. This study found no statistically significant association between eNO, COPD, and COPD severity, and occupational status did not appear to modify the association between eNO and COPD. The findings of this study highlight the importance of using objective measures such as spirometry in clinical settings for early diagnosis and management of COPD. Early diagnosis helps to slow the progression of the disease, resulting in fewer related comorbidities and complications.
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Hazari, Mehdi Saeed. "Elevated exhaled nitric oxide (ENO) in non-asthmatic atopic adults." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ58853.pdf.

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Törnberg, Daniel C. F. "Exhaled nitric oxide : influence of mechanical ventilation and vasoactive agents /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-070-2/.

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Smith, Andrew D., and n/a. "Exhaled nitric oxide measurements in the diagnosis and management of asthma." University of Otago. Dunedin School of Medicine, 2007. http://adt.otago.ac.nz./public/adt-NZDU20070924.133734.

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Introduction: The enzyme, inducible nitric oxide synthase (iNOS), is upregulated in the airway epithelium in patients with allergic asthma resulting increased nitric oxide production. The concentration of nitric oxide in exhaled air (FENO) correlates with the degree of eosinophilic airway inflammation and has been proposed as a new breath test to assist in the management of asthma. Key Aims: To determine the predictive accuracy of FENO compared with conventional testing in the diagnosis of asthma. To assess the performance characteristics of FENO to predict steroid responsiveness compared with the conventional approach in patients presenting with non-specific respiratory symptoms. To assess the role of FENO compared with conventional guidelines-based approach as a guide to adjusting inhaled corticosteroid therapy in patients with chronic persistent asthma. Methods: Consecutive patients referred with chronic undiagnosed respiratory symptoms were enrolled. Comparisons were made between FENO, induced sputum analysis and other conventional tests (including peak flow variation, spirometry, response to oral steroid challenge) for predicting the presence of asthma in the first study, and for predicting response to four weeks inhaled fluticasone treatment in the second study. In the third study, 110 subjects with chronic persistent asthma were enrolled into a single-blind placebo-controlled study during which subjects were randomly allocated to have their corticosteroid (fluticasone) dose adjusted on the basis of either FENO measurements or an algorithm based on conventional guidelines. The main outcomes were the frequency of asthma exacerbations and the mean daily dose of inhaled corticosteroid. Results: In the first study, 17 of 47 consecutive patients were diagnosed with asthma. Sensitivities for the conventional tests (0-47%) were lower than for FENO (88%) and sputum eosinophils (86%), with overall significantly greater diagnostic accuracy for FENO and sputum eosinophils. Fifty-two consecutive subjects completed the second study. When compared to the conventional tests, the predictive powers for FENO were consistently greater than for almost all other baseline measurements used to predict steroid responsiveness, with an optimum cut point of 47 ppb. In the third study, the exacerbation rates were 0.49 (95% C.I. 0.20, 0.78) per patient per year in the FENO group and 0.90 (95% C.I. 0.31, 1.49) in the control group, representing a nonsignificant reduction of 45.6 percent (95% C.I. -78.5, 54.5%) in the FENO group. The final mean daily doses of fluticasone were significantly lower in for the FENO group compared with the conventional group (370 [mu]g/day (95% C.I. 263, 477) vs 641 [mu]g/day (95% C.I. 526, 756) respectively; p=0.003). There were no significant differences in other markers of asthma control, use of oral prednisone, pulmonary function, or levels of airway inflammation (sputum eosinophils). Conclusions: FENO is comparable to induced sputum analysis and superior to the conventional methods currently used including peak flows and spirometry as a dignositic for asthma and as a predictor of steroid responsiveness in patients with chronic respiratory symptoms. FENO measurements as a guide to adjusting inhaled corticosteroid therapy compared to the conventional guidelines based approach results in significantly lower maintenance doses being achieved without compromising asthma control. The results of this thesis provide evidence to support the use of FENO measurements in routine clinical practice as a tool to improve the overall management and diagnosis of asthma.
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Books on the topic "Exhaled nitric oxide"

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Hazari, Mehdi Saeed. Elevated exhaled nitric oxide (ENO) in non-asthmatic atopic adults. Ottawa: National Library of Canada, 2001.

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1962-, Marczin Nándor, ed. Disease markers in exhaled breath. New York: M. Dekker, 2003.

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1962-, Marczin Nándor, and Yacoub Magdi, eds. Disease markers in exhaled breath: Basic mechanisms and clinical applications. Amsterdam: IOS Press, 2002.

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Barnes, Peter J., Nandor Marczin, Sergei A. Kharitonov, and Magdi H. Yacoub. Disease Markers in Exhaled Breath. Taylor & Francis Group, 2002.

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Barnes, Peter J., Nandor Marczin, Sergei Kharitonov, and Magdi Yacoub. Disease Markers in Exhaled Breath. Taylor & Francis Group, 2002.

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(Editor), Nandor Marczin, Sergei Kharitonov (Editor), Magdi Yacoub (Editor), and Peter J. Barnes (Editor), eds. Disease Markers in Exhaled Breath (Lung Biology in Health and Disease). Informa Healthcare, 2002.

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(Editor), Nandor Marczin, and Magdi Yacoub (Editor), eds. Disease Markers in Exhaled Breath: Basic Mechanisms and Clinical Applications (Nato: Life and Behavioural Sciences, 346). Ios Pr Inc, 2002.

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Airway Responsiveness and Exhaled Nitric Oxide: Studies in Asthma and Sjogren's Syndrome (Comprehensive Summaries of Uppsala Dissertations, 857). Uppsala Universitet, 1999.

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Book chapters on the topic "Exhaled nitric oxide"

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Hoyte, Flavia C. L. "Exhaled Nitric Oxide." In Encyclopedia of Medical Immunology, 285–90. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-9194-1_507.

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Kharitonov, Sergei A. "Measurement of Exhaled Nitric Oxide." In Paediatric Pulmonary Function Testing, 166–80. Basel: KARGER, 2005. http://dx.doi.org/10.1159/000083534.

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Tsujino, Ichizo, Hideki Shinano, Kenji Miyamoto, Masaharu Nishimura, and Yoshikazu Kawakami. "Measurement of Exhaled Nitric Oxide of Lung Origin." In Recent Advances in Nitric Oxide Research, 83–91. Tokyo: Springer Japan, 1999. http://dx.doi.org/10.1007/978-4-431-67929-5_7.

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Ewald-Kleimeier, S., A. Lotz, R. Merget, T. Brüning, and O. Hagemeyer. "Exhaled Nitric Oxide in Specific Inhalation Challenge." In Neurobiology of Respiration, 255–64. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6627-3_36.

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Kim, Young-Jee, Carolyn M. Kercsmar, and Stephanie D. Davis. "Fractional Exhaled Nitric Oxide: Indications and Interpretation." In Diagnostic Tests in Pediatric Pulmonology, 285–308. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1801-0_14.

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Matsunaga, Kazuto. "Diagnostic Value of Fractional Exhaled Nitric Oxide (FeNO)." In Advances in Asthma, 93–100. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2790-2_9.

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Häussermann, Sabine, Dominik Kappeler, Anje Schmidt, and Rüdiger Siekmeier. "Fractional Exhaled Nitric Oxide in Clinical Trials: An Overview." In Neurobiology of Respiration, 237–45. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6627-3_34.

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Barnes, Peter J., and Sergei A. Kharitonov. "Nitric Oxide in Exhaled Air: Relevance in Inflammatory Lung Disease." In Nitric Oxide in Pulmonary Processes: Role in Physiology and Pathophysiology of Lung Disease, 167–83. Basel: Birkhäuser Basel, 2000. http://dx.doi.org/10.1007/978-3-0348-8474-7_9.

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Gerlach, H. "The Clinical Relevance of Exhaled Nitric Oxide: A Critical Review." In Yearbook of Intensive Care and Emergency Medicine, 225–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-13455-9_20.

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Horinouchi, Hirohisa, Mitsutomo Kohno, Masatoshi Gika, Atsushi Tajima, Katsuyuki Kuwabara, Akira Yoshizu, Masao Naruke, et al. "Change of Nitric Oxide Concentration in Exhaled Gas After Lung Resection." In Oxygen Homeostasis and Its Dynamics, 569–75. Tokyo: Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-68476-3_72.

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Conference papers on the topic "Exhaled nitric oxide"

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Chazan, David, Vivek Balasubramanyam, Bhairavi Parikh, and Nina Peled. "The Effect Of Ambient Nitric Oxide On Exhaled Nitric Oxide Measurements." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4272.

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ROLLA, G. "EXHALED NITRIC OXIDE IN HEPATOPULMONARY SYNDROME." In Conference Breath Gas Analysis for Medical Diagnostics. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812701954_0011.

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Nobakht M.Gh., B. Fatemeh, and Rasoul Aliannejad. "Exhaled nitric oxide in mustard airway disease." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa1210.

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Smith, AD, JO Cowan, and DR Taylor. "Exhaled Nitric Oxide: Optimum Versus Reference Values." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5182.

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El Chami, Hala, Cheryl Fortier, Rosemary Tsacoyianis, Kari Roberts, Nicholas Hill, and Ioana Preston. "Fractional exhaled nitric oxide in pulmonary hypertension." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2492.

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Gelb, Arthur F., Roxanna Moridzadeh, Deepak Singh, Christine Fraser, and Steven C. George. "Exhaled Nitric Oxide Phenotypes During Acute Asthma." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3947.

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Schumann, Desiree, Konstantinos Kostikas, Daniel Schilter, Renaud Louis, Leticia Grize, Michael Tamm, and Daiana Stolz. "Fractionated exhaled nitric oxide in COPD patients." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa3890.

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Sivan, Yakov, Tal Gadish, Elizabeth Fireman, Tamar Merimovitch, and Ruth Soferman. "Exhaled Nitric Oxide In Acute RSV Bronchiolitis." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3310.

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Khosrow, Namjou, Roller Chad, Jeffers James, William Potter, Patrick J. Mccann, and Joe Grego. "Exhaled Nitric Oxide Measured Using Mid-Infrared Spectroscopy." In International Conference On Environmental Systems. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2002. http://dx.doi.org/10.4271/2002-01-2453.

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Calo, Johanna M., Hima Maramreddy, Joseph Boyer, and Lance A. Parton. "Is Exhaled Nitric Oxide (FENO) Useful In BPD?" In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3309.

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Reports on the topic "Exhaled nitric oxide"

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Wang, Zhen, Paolo Pianosi, Karina Keogh, Feras Zaiem, Mouaz Alsawas, Fares Alahdab, Jehad Almasri, et al. The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management. Agency for Healthcare Research and Quality, 2017. http://dx.doi.org/10.23970/ahrqepccer197.

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