Journal articles on the topic 'EV-based therapeutics'
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Williams, Katherine B., and Nicole P. Ehrhart. "Regenerative medicine 2.0: extracellular vesicle–based therapeutics for musculoskeletal tissue regeneration." Journal of the American Veterinary Medical Association 260, no. 7 (April 1, 2022): 683–89. http://dx.doi.org/10.2460/javma.22.02.0060.
Full textOCHIYA, Takahiro. "Development of extracellular vesicle (EV)-based diagnostics and therapeutics." Translational and Regulatory Sciences 2, no. 3 (2020): 80–83. http://dx.doi.org/10.33611/trs.2020-016.
Full textKlyachko, Natalia L., Camryn J. Arzt, Samuel M. Li, Olesia A. Gololobova, and Elena V. Batrakova. "Extracellular Vesicle-Based Therapeutics: Preclinical and Clinical Investigations." Pharmaceutics 12, no. 12 (December 1, 2020): 1171. http://dx.doi.org/10.3390/pharmaceutics12121171.
Full textNelson, Bryant C., Samantha Maragh, Ionita C. Ghiran, Jennifer C. Jones, Paul C. DeRose, Elzafir Elsheikh, Wyatt N. Vreeland, and Lili Wang. "Measurement and standardization challenges for extracellular vesicle therapeutic delivery vectors." Nanomedicine 15, no. 22 (September 2020): 2149–70. http://dx.doi.org/10.2217/nnm-2020-0206.
Full textDang, Xuan T. T., Jayasinghe Migara Kavishka, Daniel Xin Zhang, Marco Pirisinu, and Minh T. N. Le. "Extracellular Vesicles as an Efficient and Versatile System for Drug Delivery." Cells 9, no. 10 (September 29, 2020): 2191. http://dx.doi.org/10.3390/cells9102191.
Full textGilligan, Katie E., and Róisín M. Dwyer. "Extracellular Vesicles for Cancer Therapy: Impact of Host Immune Response." Cells 9, no. 1 (January 16, 2020): 224. http://dx.doi.org/10.3390/cells9010224.
Full textAbreu, Catarina M., Bruno Costa-Silva, Rui L. Reis, Subhas C. Kundu, and David Caballero. "Microfluidic platforms for extracellular vesicle isolation, analysis and therapy in cancer." Lab on a Chip 22, no. 6 (2022): 1093–125. http://dx.doi.org/10.1039/d2lc00006g.
Full textOvchinnikova, Leyla A., Ioanna N. Filimonova, Maria Y. Zakharova, Dmitriy S. Balabashin, Teimour K. Aliev, Yakov A. Lomakin, and Alexander G. Gabibov. "Targeting Extracellular Vesicles to Dendritic Cells and Macrophages." Acta Naturae 13, no. 3 (November 15, 2021): 114–21. http://dx.doi.org/10.32607/actanaturae.11478.
Full textBrown, Thomas J., and Victoria James. "The Role of Extracellular Vesicles in the Development of a Cancer Stem Cell Microenvironment Niche and Potential Therapeutic Targets: A Systematic Review." Cancers 13, no. 10 (May 18, 2021): 2435. http://dx.doi.org/10.3390/cancers13102435.
Full textHaney, Matthew J., Yuling Zhao, Yeon S. Jin, and Elena V. Batrakova. "Extracellular Vesicles as Drug Carriers for Enzyme Replacement Therapy to Treat CLN2 Batten Disease: Optimization of Drug Administration Routes." Cells 9, no. 5 (May 20, 2020): 1273. http://dx.doi.org/10.3390/cells9051273.
Full textAndrade, André Cronemberger, Martin Wolf, Heide-Marie Binder, Fausto Gueths Gomes, Felix Manstein, Patricia Ebner-Peking, Rodolphe Poupardin, Robert Zweigerdt, Katharina Schallmoser, and Dirk Strunk. "Hypoxic Conditions Promote the Angiogenic Potential of Human Induced Pluripotent Stem Cell-Derived Extracellular Vesicles." International Journal of Molecular Sciences 22, no. 8 (April 9, 2021): 3890. http://dx.doi.org/10.3390/ijms22083890.
Full textYan, Biying, and Yaxuan Liang. "New Therapeutics for Extracellular Vesicles: Delivering CRISPR for Cancer Treatment." International Journal of Molecular Sciences 23, no. 24 (December 12, 2022): 15758. http://dx.doi.org/10.3390/ijms232415758.
Full textChong, Suet Yen, Choon Keong Lee, Chenyuan Huang, Yi Hsuan Ou, Christopher J. Charles, Arthur Mark Richards, Yub Raj Neupane, et al. "Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers." International Journal of Molecular Sciences 20, no. 13 (July 3, 2019): 3272. http://dx.doi.org/10.3390/ijms20133272.
Full textOvchinnikova, Leyla A., Stanislav S. Terekhov, Rustam H. Ziganshin, Dmitriy V. Bagrov, Ioanna N. Filimonova, Arthur O. Zalevsky, and Yakov A. Lomakin. "Reprogramming Extracellular Vesicles for Protein Therapeutics Delivery." Pharmaceutics 13, no. 6 (May 21, 2021): 768. http://dx.doi.org/10.3390/pharmaceutics13060768.
Full textYim, Kevin Ho Wai, Ala’a Al Hrout, Simone Borgoni, and Richard Chahwan. "Extracellular Vesicles Orchestrate Immune and Tumor Interaction Networks." Cancers 12, no. 12 (December 9, 2020): 3696. http://dx.doi.org/10.3390/cancers12123696.
Full textHeath, Nikki, Xabier Osteikoetxea, Taiana Mia de Oliveria, Elisa Lázaro-Ibáñez, Olga Shatnyeva, Christina Schindler, Natalie Tigue, et al. "Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo." Nanomedicine 14, no. 21 (November 2019): 2799–814. http://dx.doi.org/10.2217/nnm-2019-0061.
Full textKhawar, Muhammad Babar, Muddasir Hassan Abbasi, Zerwa Siddique, Amin Arif, and Nadeem Sheikh. "An Update on Novel Therapeutic Warfronts of Extracellular Vesicles (EVs) in Cancer Treatment: Where We Are Standing Right Now and Where to Go in the Future." Oxidative Medicine and Cellular Longevity 2019 (July 25, 2019): 1–21. http://dx.doi.org/10.1155/2019/9702562.
Full textFujita, Yu, Tsukasa Kadota, Jun Araya, Takahiro Ochiya, and Kazuyoshi Kuwano. "Clinical Application of Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapeutics for Inflammatory Lung Diseases." Journal of Clinical Medicine 7, no. 10 (October 14, 2018): 355. http://dx.doi.org/10.3390/jcm7100355.
Full textKaddour, Hussein, Malik Tranquille, and Chioma M. Okeoma. "The Past, the Present, and the Future of the Size Exclusion Chromatography in Extracellular Vesicles Separation." Viruses 13, no. 11 (November 13, 2021): 2272. http://dx.doi.org/10.3390/v13112272.
Full textRoyo, Felix, Clotilde Théry, Juan M. Falcón-Pérez, Rienk Nieuwland, and Kenneth W. Witwer. "Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee." Cells 9, no. 9 (August 25, 2020): 1955. http://dx.doi.org/10.3390/cells9091955.
Full textVillata, Simona, Marta Canta, and Valentina Cauda. "EVs and Bioengineering: From Cellular Products to Engineered Nanomachines." International Journal of Molecular Sciences 21, no. 17 (August 22, 2020): 6048. http://dx.doi.org/10.3390/ijms21176048.
Full textDe Luca, Thomas, Robert E. Stratford, Madison E. Edwards, Christina R. Ferreira, and Eric A. Benson. "Novel Quantification of Extracellular Vesicles with Unaltered Surface Membranes Using an Internalized Oligonucleotide Tracer and Applied Pharmacokinetic Multiple Compartment Modeling." Pharmaceutical Research 38, no. 10 (October 2021): 1677–95. http://dx.doi.org/10.1007/s11095-021-03102-z.
Full textChitti, Sai V., Christina Nedeva, Raja Manickam, Pamali Fonseka, and Suresh Mathivanan. "Extracellular Vesicles as Drug Targets and Delivery Vehicles for Cancer Therapy." Pharmaceutics 14, no. 12 (December 16, 2022): 2822. http://dx.doi.org/10.3390/pharmaceutics14122822.
Full textBednova, Olga, and Jeffrey V. Leyton. "Targeted Molecular Therapeutics for Bladder Cancer—A New Option beyond the Mixed Fortunes of Immune Checkpoint Inhibitors?" International Journal of Molecular Sciences 21, no. 19 (October 1, 2020): 7268. http://dx.doi.org/10.3390/ijms21197268.
Full textZhang, Jiayi, Annie Brown, Brendan Johnson, David Diebold, Kyle Asano, Gerard Marriott, and Biao Lu. "Genetically Engineered Extracellular Vesicles Harboring Transmembrane Scaffolds Exhibit Differences in Their Size, Expression Levels of Specific Surface Markers and Cell-Uptake." Pharmaceutics 14, no. 12 (November 23, 2022): 2564. http://dx.doi.org/10.3390/pharmaceutics14122564.
Full textKoul, Sneh, Victoria L. Schaal, Subhash Chand, Steven T. Pittenger, Neetha Nanoth Vellichirammal, Vikas Kumar, Chittibabu Guda, Rick A. Bevins, Sowmya V. Yelamanchili, and Gurudutt Pendyala. "Role of Brain Derived Extracellular Vesicles in Decoding Sex Differences Associated with Nicotine Self-Administration." Cells 9, no. 8 (August 11, 2020): 1883. http://dx.doi.org/10.3390/cells9081883.
Full textNeri, Paola, Kathy Gratton, Li Ren, Jordan Johnson, Jiri Slaby, Peter Duggan, Douglas A. Stewart, and Nizar J. Bahlis. "Role of Mir-30e in Multiple Myeloma Cells Resistance to Lenalidomide and Bortezomib." Blood 120, no. 21 (November 16, 2012): 323. http://dx.doi.org/10.1182/blood.v120.21.323.323.
Full textJain, Rohit K., Youngchul Kim, Jennifer Rembisz, Richard Piekarz, Timothy W. Synold, Jingsong Zhang, and Guru P. Sonpavde. "Phase Ib trial of erdafitinib (E) combined with enfortumab vedotin (EV) following platinum and PD-1/L1 inhibitors for metastatic urothelial carcinoma (mUC) with FGFR2/3 genetic alterations (GAs)." Journal of Clinical Oncology 40, no. 6_suppl (February 20, 2022): TPS595. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.tps595.
Full textNwizu, Chibuikem Chukwudalu, Lorin Crawford, Theo Borgovan, Sicheng Wen, Mark S. Dooner, Pamela C. Egan, John L. Reagan, Adam J. Olszewski, Laura R. Goldberg, and Peter J. Quesenberry. "Using Machine Learning to Classify the "Goodness" of Hmsc-Derived and AML-Derived EV's." Blood 132, Supplement 1 (November 29, 2018): 5244. http://dx.doi.org/10.1182/blood-2018-99-120183.
Full textHuntington, Scott F., Stephen J. Schuster, Wei He, Tong Shen, Heather Walker, Laura Leary, Kylie Boyhen, et al. "Phase I Study of First-in-Class Oral Triplet Therapy DTRM-555 in Relapsed/Refractory Lymphoma Patients through Fixed-Dose Combination and Synthetic Lethality." Blood 132, Supplement 1 (November 29, 2018): 5384. http://dx.doi.org/10.1182/blood-2018-99-112944.
Full textMassaro, Crescenzo, Giulia Sgueglia, Victoria Frattolillo, S. Rubina Baglio, Lucia Altucci, and Carmela Dell'Aversana. "Extracellular Vesicle-Based Nucleic Acid Delivery: Current Advances and Future Perspectives in Cancer Therapeutic Strategies." Pharmaceutics 12, no. 10 (October 16, 2020): 980. http://dx.doi.org/10.3390/pharmaceutics12100980.
Full textSherman, Cherrie D., Shweta Lodha, and Susmita Sahoo. "EV Cargo Sorting in Therapeutic Development for Cardiovascular Disease." Cells 10, no. 6 (June 15, 2021): 1500. http://dx.doi.org/10.3390/cells10061500.
Full textCouto, Nuno, Julia Elzanowska, Joana Maia, Silvia Batista, Catarina Esteves Pereira, Hans Christian Beck, Ana Sofia Carvalho, et al. "IgG+ Extracellular Vesicles Measure Therapeutic Response in Advanced Pancreatic Cancer." Cells 11, no. 18 (September 8, 2022): 2800. http://dx.doi.org/10.3390/cells11182800.
Full textKamal, Asif, Urooj Haroon, Hakim Manghwar, Khalid H. Alamer, Ibtisam M. Alsudays, Ashwaq T. Althobaiti, Anila Iqbal, et al. "Biological Applications of Ball-Milled Synthesized Biochar-Zinc Oxide Nanocomposite Using Zea mays L." Molecules 27, no. 16 (August 22, 2022): 5333. http://dx.doi.org/10.3390/molecules27165333.
Full textZhao, Yuling, Matthew J. Haney, John K. Fallon, Myosotys Rodriguez, Carson J. Swain, Camryn J. Arzt, Philip C. Smith, et al. "Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease." Cells 11, no. 12 (June 15, 2022): 1933. http://dx.doi.org/10.3390/cells11121933.
Full textHua, Shu, Peter Mark Bartold, Karan Gulati, Corey Stephen Moran, Sašo Ivanovski, and Pingping Han. "Periodontal and Dental Pulp Cell-Derived Small Extracellular Vesicles: A Review of the Current Status." Nanomaterials 11, no. 7 (July 19, 2021): 1858. http://dx.doi.org/10.3390/nano11071858.
Full textSimeone, Pasquale, Christian Celia, Giuseppina Bologna, Eva Ercolino, Laura Pierdomenico, Felisa Cilurzo, Rossella Grande, et al. "Diameters and Fluorescence Calibration for Extracellular Vesicle Analyses by Flow Cytometry." International Journal of Molecular Sciences 21, no. 21 (October 23, 2020): 7885. http://dx.doi.org/10.3390/ijms21217885.
Full textJabalee, James, Rebecca Towle, and Cathie Garnis. "The Role of Extracellular Vesicles in Cancer: Cargo, Function, and Therapeutic Implications." Cells 7, no. 8 (August 1, 2018): 93. http://dx.doi.org/10.3390/cells7080093.
Full textDu, Rong, Chen Wang, Ling Zhu, and Yanlian Yang. "Extracellular Vesicles as Delivery Vehicles for Therapeutic Nucleic Acids in Cancer Gene Therapy: Progress and Challenges." Pharmaceutics 14, no. 10 (October 19, 2022): 2236. http://dx.doi.org/10.3390/pharmaceutics14102236.
Full textKee, Li Ting, Chiew Yong Ng, Maimonah Eissa Al-Masawa, Jhi Biau Foo, Chee Wun How, Min Hwei Ng, and Jia Xian Law. "Extracellular Vesicles in Facial Aesthetics: A Review." International Journal of Molecular Sciences 23, no. 12 (June 16, 2022): 6742. http://dx.doi.org/10.3390/ijms23126742.
Full textWang, Jing, Alain Wuethrich, Abu Ali Ibn Sina, Rebecca E. Lane, Lynlee L. Lin, Yuling Wang, Jonathan Cebon, Andreas Behren, and Matt Trau. "Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma." Science Advances 6, no. 9 (February 2020): eaax3223. http://dx.doi.org/10.1126/sciadv.aax3223.
Full textDriscoll, Julia, Irene K. Yan, and Tushar Patel. "Development of a Lyophilized Off-the-Shelf Mesenchymal Stem Cell-Derived Acellular Therapeutic." Pharmaceutics 14, no. 4 (April 13, 2022): 849. http://dx.doi.org/10.3390/pharmaceutics14040849.
Full textJung, Youn Jae, Hark Kyun Kim, Yoonsuk Cho, Ji Suk Choi, Chang Hee Woo, Kyoung Soo Lee, Jae Hoon Sul, et al. "Cell reprogramming using extracellular vesicles from differentiating stem cells into white/beige adipocytes." Science Advances 6, no. 13 (March 2020): eaay6721. http://dx.doi.org/10.1126/sciadv.aay6721.
Full textOllen-Bittle, Nikita, Austyn D. Roseborough, Wenxuan Wang, Jeng-liang D. Wu, and Shawn N. Whitehead. "Mechanisms and Biomarker Potential of Extracellular Vesicles in Stroke." Biology 11, no. 8 (August 18, 2022): 1231. http://dx.doi.org/10.3390/biology11081231.
Full textMcLaughlin, Caroline, Pallab Datta, Yogendra P. Singh, Alexis Lo, Summer Horchler, Irina A. Elcheva, Ibrahim T. Ozbolat, Dino J. Ravnic, and Srinivas V. Koduru. "Mesenchymal Stem Cell-Derived Extracellular Vesicles for Therapeutic Use and in Bioengineering Applications." Cells 11, no. 21 (October 25, 2022): 3366. http://dx.doi.org/10.3390/cells11213366.
Full textWiklander, Oscar P. B., Meadhbh Á. Brennan, Jan Lötvall, Xandra O. Breakefield, and Samir EL Andaloussi. "Advances in therapeutic applications of extracellular vesicles." Science Translational Medicine 11, no. 492 (May 15, 2019): eaav8521. http://dx.doi.org/10.1126/scitranslmed.aav8521.
Full textZhang, Haiyang, Qi Zhang, Yuanyuan Deng, Mengxi Chen, and Chenxi Yang. "Improving Isolation of Extracellular Vesicles by Utilizing Nanomaterials." Membranes 12, no. 1 (December 31, 2021): 55. http://dx.doi.org/10.3390/membranes12010055.
Full textBatool, Syeda Maheen, Tiffaney Hsia, Sirena K. Khanna, Austin S. Gamblin, Yulia Rosenfeld, Dong Gil You, Bob S. Carter, and Leonora Balaj. "Decoding vesicle-based precision oncology in gliomas." Neuro-Oncology Advances 4, Supplement_2 (November 11, 2022): ii53—ii60. http://dx.doi.org/10.1093/noajnl/vdac035.
Full textPhan, Thanh Kha, Dilara Ceyda Ozkocak, and Ivan Ka Ho Poon. "Unleashing the therapeutic potential of apoptotic bodies." Biochemical Society Transactions 48, no. 5 (September 1, 2020): 2079–88. http://dx.doi.org/10.1042/bst20200225.
Full textNair, Ashita, Jiyoon Bu, Piper A. Rawding, Steven C. Do, Hangpeng Li, and Seungpyo Hong. "Cytochalasin B Treatment and Osmotic Pressure Enhance the Production of Extracellular Vesicles (EVs) with Improved Drug Loading Capacity." Nanomaterials 12, no. 1 (December 21, 2021): 3. http://dx.doi.org/10.3390/nano12010003.
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