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AYERS, Mimi. "Defending Eulalie." ScholarWorks@UNO, 2018. https://scholarworks.uno.edu/td/2562.
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Andersen, David Hess Jonathan M. "Parody as criticism the literary life of Eulalia Meinau /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1550.
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Thesis (M.A.)--University of North Carolina at Chapel Hill, 2008.Title from electronic title page (viewed Sep. 16, 2008). "... in partial fulfillment of the requirements for the degree of Master of Arts in the Department of Germanic Languages and Literature." Discipline: Germanic Languages; Department/School: Germanic Languages.
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Smith, T. P. L. "Petrogenesis of a composite Hercynian pluton, Santa Eulalia, Portugal." Thesis, University of Reading, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233641.
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Wang, Jin. "Arbitrary Lagrangian-Eularian method and its application in solid mechanics." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0016/NQ27267.pdf.
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Bond, Brian Robert 1958. "Selective trace element geochemistry, San Antonio Mine, Santa Eulalia, Chihuahua." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/558066.
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Kallin, Marianne. "La función de los narradores en Cinco sombras de Eulalia Galvarriato." Thesis, Linnéuniversitetet, Institutionen för språk (SPR), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-31469.
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Puig, Moneva María Soledad. "La Colonia de Santa Eulalia. El patrimonio industrial como patrimonio cultural." Doctoral thesis, Universitat Politècnica de València, 2017. http://hdl.handle.net/10251/76167.
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In the early 19th century, a series of reformist movements arose in Europe. They were based on "The Enlightenment" theories trying to find solutions to the problems caused by the Industrial Revolution. The group which had the greatest repercussion was the Utopian Socialism. Their ideologists proposed the creation of new settlements to be located far away from the corruption and chaos of the big cities, where a new moral economic system could be established. These philanthropists would act as a paternalistic figure for their workers. As for Spain, its precarious political and economic situation hindered a theoretical development similar to the rest of European countries. However, foreign Utopian ideas would influence greatly the first Spanish agricultural colonization laws, intended to repopulate Spain's countryside. Many colonies or villages of urban and architectural interest were created throughout the country. Although, to begin with these places would concentrate on agricultural production, laws allowed for any other types of industrial activity.
This Doctoral Thesis focuses on the analysis of the agroindustrial Colony of Santa Eulalia, situated between the towns of Sax and Villena, in Alicante. It is a fine example of industrial and interior colonization from the end of the 19th century in the Valencian Community and still today maintains its original appearance. This exceptional village was created by Antonio de Padua y Saavedra in 1886. It operated self-sufficiently for several decades since its produce was gathered from its lands, prepared and commercialized in its own flour and alcohol factories and oil mill. The colony also had a chapel, the owners' mansion house, the workers housing and various stores and leisure facilities. Nowadays, its advanced state of deterioration and neglect could lead to the loss of this heritage site. Thus, the reason why this work includes an initial assessment for its restoration and enhancement of its value by reusing its buildings and revitalizing its surroundings. All of the aforementioned could be used as a starting point for future projects that would guarantee its preservation.A principios del siglo XIX, surgen en Europa una serie de movimientos reformistas que, basándose en las teorías ilustradas, intentaron buscar soluciones a los problemas derivados de la Revolución Industrial. La corriente que obtuvo una mayor repercusión fue el Socialismo Utópico. Sus ideólogos proponían la creación de unos nuevos asentamientos, alejados del caos y la corrupción de las grandes ciudades, donde se establecería un nuevo sistema moral y económico a partir un control paternalista ejercido por el empresario sobre sus trabajadores. En España, la precaria situación de la economía y la política impidió un desarrollo teórico como en el resto de países europeos. Sin embargo, las ideas utópicas extranjeras ejercerían una influencia importante en las primeras leyes colonizadoras agrícolas para la repoblación del campo español, a partir de las cuales se crearían por toda la geografía del país una serie de colonias o poblados de gran interés urbano y formal. Aunque, en un principio, estos espacios se centrarían en la producción agraria, los textos legislativos daban también cabida a las construcciones fabriles de diferente naturaleza. La presente Tesis Doctoral se centra en el análisis de la Colonia agroindustrial de Santa Eulalia, entre las poblaciones de Sax y Villena (Alicante). Es un ejemplo característico de colonización interior e industrial de finales del siglo XIX en la Comunidad Valenciana y, desde su creación, se ha mantenido prácticamente intacta. Este singular poblado, concebido por Antonio de Padua y Saavedra, comenzó a construirse en 1886 y funcionó de forma autosuficiente durante varias décadas, ya que los productos agrícolas que se recolectaban en sus terrenos se transformaban y comercializaban en sus dos grandes fábricas, de alcoholes y harinas, y en la almazara. El conjunto contó, además, con una ermita, una casa-palacio para los propietarios, las viviendas de los obreros y diversos comercios y servicios de ocio. En la actualidad, su avanzado estado de deterioro y abandono podría suponer la pérdida del conjunto patrimonial. Es por ello por lo que este trabajo incluye una aproximación inicial a su recuperación y puesta en valor a partir de la reutilización de sus edificios y la revitalización de su entorno, que puede servir de punto de partida para una futura intervención que garantice su conservación.
A principis del segle XIX, sorgiren a Europa una sèrie de moviments reformistes que, basant-se en les teories il·lustrades, intentaren trobar solucions als problemes derivats de la Revolució Industrial. El corrent que va obtenir una major repercussió fou el Socialisme Utòpic. Els seus ideòlegs proposaven la creació d'uns nous assentaments, allunyats del caos i la corrupció de les grans ciutats, a on s'establiria un nou sistema moral i econòmic a partir d'un control patern exercit per l'empresari sobre els seus treballadors. A Espanya, la precària situació de l'economia i la política impediren un desenvolupament teòric com a la resta de països europeus. No obstant, les idees utòpiques estrangeres exercirien una influència important a les primeres lleis colonitzadores agrícoles per a la repoblació del camp espanyol, a partir de les quals es crearien per tota la geografia del país una sèrie de colònies o poblats de gran interès urbà i formal. Encara que, en un principi, aquests espais es centrarien en la producció agrària, els textos legislatius donaven també cabuda a les construccions fabrils de diferent natura. La present Tesi Doctoral es centra en l'anàlisi de la Colònia agroindustrial de Santa Eulàlia, entre les poblacions de Sax i Villena (Alacant). És un exemple característic de colonització interior i industrial de finals del segle XIX a la Comunitat Valenciana i, des de la seua creació, s'ha mantingut pràcticament intacta. Aquest singular poblat, concebut per Antonio de Padua y Saavedra, començà a construir-se el 1886 i funcionà de forma autosuficient durant vàries dècades, ja que els productes agrícoles que es recol·lectaven als seus terrenys es transformaven i comercialitzaven a les seues dues grans fàbriques, d'alcohols i farines, i a l'almàssera. El conjunt va contar, a més, amb una ermita, una casa-palau pels propietaris, les vivendes dels obrers i diversos comerços i servicis d'oci. Actualment, el seu avançat estat de deteriorament i abandonament podria suposar la pèrdua del conjunt patrimonial. És per això pel que aquest treball inclou una aproximació inicial a la seua recuperació i posada en valor a partir de la reutilització dels seus edificis i la revitalització del seu entorn, que pot servir de punt de partida per a una futura intervenció que garantisca la seua conservació.
Puig Moneva, MS. (2016). La Colonia de Santa Eulalia. El patrimonio industrial como patrimonio cultural [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/76167
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Megaw, Peter Kenneth McNeill. "Geology and geochemistry of the Santa Eulalia mining district, Chihuahua, Mexico." Diss., The University of Arizona, 1990. http://hdl.handle.net/10150/187549.
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Santa Eulalia contains two separate, contrasting Pb-Zn-Ag deposits. The East Camp consists of a symmetrically zoned calc-silicate skarn with distal sulfide and tin-bearing orebodies; whereas the west Camp is composed of massive sulfide orebodies with minor proximal calc-silicate skarn and isolated intermediate calcic-iron skarns. Mineralization and alteration are zoned within each camp but do not overlap. Sulfide mineralization in both camps consists of pyrrhotite, sphalerite, galena, and pyrite with lesser amounts of arsenopyrite and chalcopyrite. The East Camp is apparently richer in zinc and copper than the West camp. Mineralization is temporally and spatially related to geochemically identical felsite intrusions which apparently have a common source. Mineralizing fluids followed these felsites through a thick section of evaporites and organic-rich shaly limestones into clean, homogeneous,
relatively undeformed, limestone hosts. West Camp mineralization occurs along an interconnected network of vertically discontinuous tight fissures and sill contacts, whereas East Camp mineralization is located along vertically throughgoing faults and dike contacts. strata-bound, but not stratiform, mantos extend off discordant chimneys in both camps. Ore textures reveal that mineralization occurred primarily by limestone replacement. 21 Pressure-corrected primary fluid inclusion homogenization temperatures in fluorite range from 220 to 490 deg. C. Salinities are bimodal with high-salinity (>26.3 equivalent wt% NaCl) and low-salinity (1-12 equivalent wt% NaCl) populations. Mineralogical constraints indicate that the hydrothermal fluids were acid and reduced. Sulfur isotope analyses indicate that the ore fluids varied from -17 to +4 permil without correlation to iron-sulfide species,
temperature, or salinity. Co-existing sulfides are commonly in isotopic disequilibrium. Sulfur isotopes from the West Camp are crudely zoned, but no consistent patterns exist in the East Camp. Oxygen and carbon isotope analyses of limestone wallrocks reveal a distinct isotopic alteration halo. A single analysis of gangue calcite from each camp indicates that the ore fluids contained non-carbonate-derived carbon and oxygen, possibly of magmatic origin. Metals were apparently transported as chloride complexes
and deposited through coupled dissolution-precipitation replacement reactions. Most ore sulfur apparently came from diagenetic pyrite and sedimentary anhydrite, but some of the sulfur may have had a magmatic source. The metals probably came from the felsite parent magma and this magma may have also contributed fluids. Close similarities between Santa Eulalia and numerous other intrusion-related carbonate-hosted deposits in northern Mexico reinforce these interpretations.
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Walter, Timothy George. "METALS DISTRIBUTION AT THE SAN ANTONIO MINE, SANTA EULALIA MINING DISTRICT, CHIHUAHUA, MEXICO." Thesis, The University of Arizona, 1985. http://hdl.handle.net/10150/275296.
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Fraai, Jenny. "Rebeldías camufladas : análisis de tres novelas femininas de los años cuarenta en España /." Alcalá de Henares : Ayuntamiento de Alcalá de Henares : Centro asesor de la mujer, 2003. http://catalogue.bnf.fr/ark:/12148/cb39987787b.
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Rodrigues, Fabio Della Paschoa. "Um diletante na universidade : historia e critica literaria em Alexandre Eulalio." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/270235.
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Orientador: Antonio Arnoni PradoDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem
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Resumo: O presente trabalho examina a crítica literária produzida por Alexandre Eulalio (1932-1988), percorrendo sua trajetória intelectual, de jovem estudante iniciando sua contribuição em jornais e revistas, passando pela função de redator da Revista do Livro, até ingressar, como professor convidado, na Universidade Estadual de Campinas. Com formação conduzida, sobretudo, pelo autodidatismo, numa época em que a figura do diletante não era bem vista, será na universidade que a atividade crítica tomará a maior parte do tempo desse intelectual múltiplo, que atuou como editor, historiador, crítico, professor e pesquisador. A pesquisa procura mostrar que o trabalho do crítico era contido pelo do jornalista, do editor e do historiador, encontrando ambiente favorável ao desenvolvimento de sua atividade crítica, depois, no âmbito universitário, onde Eulalio ingressa primeiro como professor convidado em instituições estrangeiras e depois como professor notório saber na Unicamp. O estudo analisa ainda como a crítica de Eulalio, que alia o saber histórico à análise formal, é movida pela paixão e pela identificação do crítico com o objeto contemplado, que interfere na seleção dos nomes, no tratamento dado e na própria composição do texto crítico, que espelha as características da obra ou do autor analisado
Abstract: This dissertation examines the literary criticism produced by Alexandre Eulalio (1932-1988), tracing his intellectual trajectory from the beginning of his contribution to newspapers and magazines as a young student, going through his work as editor of Revista do Livro, until he joins Campinas State University as a guest professor. With a formation especially marked by autodidacticism, at a time when the figure of dilettante was not well regarded, it would be at university that criticism should take most of the multiskilled intellectual¿s time, who worked as editor, historian, critic, teacher and researcher. This research seeks to support the claim that his work as critic was constricted by that as journalist, editor and historian, finding shelter for its later development, in a university environment, where Eulalio comes first as a visiting professor at foreign universities and afterwards as a professor of notorious knowledge at Unicamp. This study also examines how the criticism of Eulalio, which gathers historical knowledge and formal analysis, is moved by the passion and identification of the critic with the contemplated object, something that interferes in his selection of authors, in his treatment of the subject, and in the composition of criticism itself, reflecting features of the work or author under analysis
Mestrado
Teoria e Critica Literaria
Mestre em Teoria e História Literária
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Gómez, Martín Eulalia [Verfasser]. "Thinking in Systems, Thinking in Nature: Evaluating the long-term performance of Nature Based Solutions / Eulalia Gómez Martín." Hamburg : Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky, 2020. http://d-nb.info/1234658364/34.
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Palomino, Ramírez Vani, and Estrada Luis Ricardo Mauricio. "Modelamiento hidrológico e hidráulico para un sistema de alerta temprana en la quebrada Cashahuacra, distrito de Santa Eulalia." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626417.
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El presente trabajo consiste en el modelamiento hidrológico e hidráulico de la quebrada Cashahuacra ubicada en el distrito de Santa Eulalia con el fin de proponer la estructura de un sistema de alerta temprana que integre estos modelos para evitar la pérdida, primordialmente, de vidas humanas.
Se presenta una síntesis de los principales eventos de flujo de detritos ocurridos en dicho lugar así como un marco teórico que aborda conceptos básicos relacionados al estudio de la hidrología e hidráulica.
Para el modelo hidrológico, se llevó a cabo la caracterización de la quebrada Cashahuacra y se obtuvo sus parámetros principales, así también, fue necesario la adquisición de los datos históricos de precipitación. De esta manera, el modelo hidrológico fue realizado con el software HEC-HMS versión 4.2 en colaboración con ArcGIS versión 10.2.1. y su extensión HEC-GeoHMS. Así, se pudo determinar los caudales máximos bajo los periodos de retorno de 5, 10, 20, 50, 100, 200 y 500 años.
El modelo hidráulico fue desarrollado con el software FLO-2D versión PRO. Tuvo como parámetros de entrada al hidrograma calculado por el modelo hidrológico, a la topografía digital del terreno, y a parámetros reológicos como la viscosidad y el esfuerzo de cedencia. Luego, fueron obtenidas las velocidades y profundidades máximas de los periodos de retorno mencionados líneas arriba.
Finalmente, se ha integrado estas dos modelaciones en la estructura de un sistema de alerta temprana frente a huaycos y se ha sugerido la implementación de un radar meteorológico para la quebrada en estudio.The present work consists of hydrological and hydraulic modeling of the Cashahuacra stream located in the Santa Eulalia district in order to propose the structure of an early warning system that integrates these models to avoid the loss, primarily of human lives. A synthesis of the main debris flow events occurring in that place is presented as well as a theoretical framework that addresses basic concepts related to the study of hydrology and hydraulics. For the hydrological model, the characterization of the Cashahuacra stream was carried out and its main parameters were obtained, as well as the acquisition of the historical precipitation data. In this way, the hydrological model was made with the HEC-HMS software version 4.2 in collaboration with ArcGIS version 10.2.1. and its HEC-GeoHMS extension. Thus, it was possible to determine the maximum flow rates under the return periods of 5, 10, 20, 50, 100, 200 and 500 years. The hydraulic model was developed with the FLO-2D PRO version software. It had as input parameters to the hydrograph calculated by the hydrological model, to the digital topography of the land, and to rheological parameters such as viscosity and yield strength. Then, the maximum speeds and depths of the return periods mentioned above were obtained. Finally, these two models have been integrated into the structure of an early warning system against hurricanes and the implementation of a meteorological radar for the stream under study has been suggested.
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Fraai, Jenny. "Rebeldías camufladas : análisis de tres novelas femeninas de los años cuarenta en España /." Madrid : Centro Asesor de la Mujer, 2002. http://www.gbv.de/dms/sub-hamburg/373606869.pdf.
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Ayala, Ojeda Stephanie Geraldine. "Metodología para determinar la población damnificada como demanda ante la ocurrencia de huaicos en la ciudad de Santa Eulalia." Bachelor's thesis, Pontificia Universidad Católica del Perú, 2020. http://hdl.handle.net/20.500.12404/18097.
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El presente trabajo de investigación parte de analizar la importancia de la logística en el
ámbito humanitario y el peligro ante la ocurrencia de huaicos en el Perú debido a las
características geográficas de su ubicación por presentarse fenómenos meteorológicos
como el Fenómeno del Niño y por la presencia de la Cordillera de los Andes que ocasiona
formaciones geológicas y geomorfológicas en el territorio peruano. Es por ello que se
propone una metodología que permita estimar la cantidad de población damnificada como
demanda de la logística humanitaria ante la ocurrencia de huaicos en la ciudad de Santa
Eulalia con un nivel de intensidad alta, es decir, se activarán todas las quebradas presentes
en la ciudad afectando al 100% de la población que habita en las zonas críticas.
La metodología presentada se basa en información demográfica y geográfica de la zona de
estudio, y de información sobre los riesgos y peligros identificados por INDECI, para
posteriormente aplicar métodos de proyección de la población para estimar la cantidad de
personas damnificadas por sector crítica predefinido. Tras la aplicación de la metodología en
la ciudad de estudio, se estimó un total de 3,930 damnificados que requerirían de bienes de
ayuda humanitaria (alimento, refugio, entre otros enceres) tras la ocurrencia de huaicos en
la zona. Se trabajo bajo los supuestos de las tasas de crecimiento poblacional anual del
distrito y de la ciudad de Santa Eulalia son iguales y que las proporciones de población por
sector crítico indicadas por INDECI son constantes a través del paso del tiempo.
La metodología propuesta presenta limitaciones, pero puede ser utilizada como punto de
partida para futuras investigaciones bajo escenarios con diferentes desastres naturales y en
diferentes niveles de intensidad.Trabajo de investigación
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Pilco, Lazarte Jesús E. "Santa Eulalia : la vulnerabilidad de un distrito rural con características urbanas : una aproximación desde el enfoque espacial y político-institucional." Bachelor's thesis, Pontificia Universidad Católica del Perú, 2015. http://tesis.pucp.edu.pe/repositorio/handle/123456789/8490.
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A nivel urbano, el funcionamiento sistémico de las ciudades está acompañado de un doble enfoque, tanto espacial como político-institucional. A nivel espacial, nos referimos a la distribución de los elementos esenciales que permiten el funcionamiento del territorio urbano; mientras que el nivel político-institucional, se refiere a la multiplicidad de actores que gestionan el servicio o recurso de una ciudad. En esta investigación, utilizaremos estos dos enfoques para explicar y analizar la vulnerabilidad del distrito de Santa Eulalia, ubicada en la provincia rural de Huarochirí, en base a su proximidad con la gran aglomeración de Lima Metropolitana, tanto en situación normal como en situación de emergencia. Para ello, utilizaremos la metodología propuesta por el Instituto de Investigación Francés para el Desarrollo (IRD), por ser novedosa al abordar los estudios de riesgo desde un enfoque territorial, la cual adaptaremos a un nivel local. La investigación busca ser un aporte, a los estudios y proyectos de la Gestión de Riesgo de Desastres que se desarrollen y relacionen con la seguridad física de las pequeñas aglomeraciones urbana ubicadas a lo largo de la sub-cuenca del río Santa EulaliaTesis
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Fraai-Roem, Jentine Catharina. "Rebeldias camufladas análisis de tres novelas femeninas de los años cuarenta en España /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2002. http://dare.uva.nl/document/65224.
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Lima, Irailde do Nascimento. "Amplitude e sobreposição do nicho ecológico de Euglossa cordata e Eulaema nigrita (Hymenoptera, Apidae, Euglossini)." reponame:Repositório Institucional da UFC, 2017. http://www.repositorio.ufc.br/handle/riufc/23728.
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LIMA, Irailde do Nascimento. Amplitude e sobreposição do nicho ecológico de Euglossa cordata e Eulaema nigrita (Hymenoptera, Apidae, Euglossini). 2017. 61 f. Dissertação (Mestrado em Zootecnia)– Universidade Federal do Ceará, Fortaleza, 2017.Submitted by Francisca Gomes (francisbeserra@yahoo.com.br) on 2017-06-27T17:47:46Z No. of bitstreams: 1 2017_dis_inlima.pdf: 1632135 bytes, checksum: 918cc10f876699ef6b93672c3b08316d (MD5)
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This study was deseloped at four ranches of the urban area of the municipal district of São Carlos – São Paulo, Brazil, in the period of November of 2005 to January of 2007, analyzing pollen loads of females of Euglossa cordata and Eulaema nigrita that have visited flowers of Thevetia peruviana (Apocynaceae) in the streets of the city, and shown points of coccurence of those bees in the Neotropical Region. The objective was to evaluate the overlap of trophic niches for the immatures in collection places and the amplitude of ecological niches between the two species of bees. Qualitative and quantitative analyses were accomplished on 175 pollen load samples for Euglossa cordata and 45 for Eulaema nigrita collected at the four ranches of the urban area, and made modeling the ecological niche starting from the construction maps of potential distribution for the two species of bees and and species of more abundant plants species in their diets. The analysis showed 37 pollen types used in the diet of Euglossa cordata and 12 for Eulaema nigrita, where the species of more abundant plant in the diet of both bees were Psidium guajava L. (Myrtaceae), Tradescantia zebrina Heynh. ex Bosse (Commelinaceae) and Solanum paniculatum L. (Solanaceae). The types more frequent pollen in the diet toEulaema nigrita were of Solanum paniculatum and Psidium guajava, while Euglossa cordatacollected Solanum paniculatum and Tradescantia zebrina, being Solanum paniculatum the plant species shared by both species of bee. The modeling of potential distribution, for Euglossa cordataand Eulaema nigritashowed that both evince potential distribution similar in areas of occurrence in the Neotropical region, and they overlap in the distribution of ecological niche in most areas of occurrence in the region.
O presente estudo foi desenvolvido em quatro sítios da área urbana do município de São Carlos - São Paulo, no período de novembro de 2005 a janeiro de 2007, analisando a carga polínica das fêmeas de Euglossa cordata e Eulaema nigrita que visitaram flores de Thevetia peruviana (Apocynaceae) nas ruas da cidade, e mostrando pontos de ocorrência dessas abelhas na Região Neotropical. O objetivo foi avaliar a sobreposição do nicho trófico para os imaturos, os sítios de coleta e a amplitude do nicho ecológico entre as duas espécies de abelhas. Foram feitas análises qualitativas e quantitativas de 175 amostras de carga polínica para Euglossa cordata e 45 para Eulaema nigrita, coletados nos quatros sítios da área urbana, e feita a modelagem do nicho ecológico a partir da construção de mapas de distribuição potencial para as duas espécies de abelhas e espécies de plantas mais abundantes em suas dietas. As análises mostraram 37 tipos polínicos usados na dieta da Euglossa cordata e 12 para Eulaema nigrita, em que as espécies de plantas mais abundantes na dieta das duas abelhas foram: Psidium guajava L. (Myrtaceae), Tradescantia zebrina Heynh. ex Bosse (Commelinaceae) e Solanum paniculatum L. (Solanaceae). Os tipos polínicos mais frequentes na dieta de Eulaema nigrita foram os de Solanum paniculatum e Psidium guajava, enquanto que Euglossa cordata coletou Solanum paniculatum e Tradescantia zebrina, sendo Solanum paniculatum a espécie de planta compartilhada pelas duas espécies de abelha. O modelo de distribuição potencial para Euglossa cordata e Eulaema nigrita mostrou que ambas exibem distribuição potencial semelhante nas áreas de ocorrência da região Neotropical, e se sobrepõem em distribuição do nicho ecológico na maior parte de ocorrência nessa região.
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Ortega, Balanza Marta. "Eulalia Ferrer, viuda de Brusi: paradigma de la capacidad de obrar de las mujeres en la edición y librería barcelonesa del siglo XIX." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/664889.
Full textAbstract:
En las “profesiones del libro”, hasta el siglo XIX, las mujeres (la mayoría sin educación ni formación, salvo lo que correspondía “a su naturaleza”) eran de iure meros personajes de transición entre los varones titulares del negocio, siendo una de las causas principales las trabas normativas que impedían o limitaban su desarrollo en todos los ámbitos de actuación: vida, educación, formación y profesión, sin olvidar los discursos ideológicos de la época. El objetivo de esta tesis doctoral es estudiar la capacidad de obrar de las mujeres al frente de los negocios de librería, imprenta y edición, de la mano de Eulàlia Ferrer Montserrat (de casada Brusi, 1780-1841): su ejercicio en diferentes ámbitos, instancias y niveles de actuación y la conformación de su identidad profesional. Partiendo de que la capacidad jurídica en base a la titularidad de derechos se planteaba como universal, ahondamos en su capacidad de obrar real que, por el hecho de ser mujer, la constreñía jurídica y reglamentariamente, determinando una subordinación y dependencia en relación directa con su estado civil.A les “professions del llibre”, fins al segle XIX, les dones (la majoria sense educació ni formació, llevat de la que corresponia “a la seva naturalesa”) eren, de iure, mers personatges de transició entre els barons titulars del negoci, essent un dels motius principals les traves normatives que impedien o limitaven llur desenvolupament en tots els àmbits d’actuació: vida, educació, formació i professió, sense oblidar els discursos ideològics de l’època. L’objectiu d’aquesta tesi doctoral és estudiar la capacitat d’obrar de les dones al capdavant dels negocis de llibreteria, impremta i edició, de la mà de Eulàlia Ferrer Montserrat (de casada Brusi, 1780-1841): el seu exercici en diferents àmbits, instàncies i nivells d’actuació i la conformació de la seva identitat professional. A partir del fet que la capacitat jurídica en base a la titularitat de drets es plantejava com a universal, aprofundim en la seva capacitat d’obrar real que, pel fet d’ésser dona, la constrenyia jurídicament y reglamentària, determinant una subordinació i dependència en relació directa amb el seu estat civil.
Dans “les métiers du livre” jusqu’au XIXe siècle, les femmes (la plupart sans éducation ni formation, hormis ce qui correspond à leur nature) étaient de iure, de simples personnages de transition entre les hommes titulaires de l’entreprise, les obstacles normatifs étant une des causes principales qui empêchaient ou limitaient leur développement dans tous les domaines de leur vie: éducation, formation et profession; sans oublier les discours idéologiques de l’époque. L’objectif de cette thèse doctorale est d’étudier la capacité d’action des femmes à la tête des affaires ayant trait au livre, à l’imprimerie et à l’édition, en accompagnant à Eulàlia Ferrer Montserrat (épouse Brusi, 1780-1841), son exercice dans plusieurs domaines et son niveau d’intervention et la création de son identité professionnelle. En considérant que la capacité juridique basée sur la titularisation de droits était envisagée comme universelle nous approfondissons sa capacité réelle d’agir qui, par le fait d’être femme la contraignait juridiquement et réglementairement en déterminant une subordination et une dépendance en relation directe avec son état civil.
Within the “professions of the book”, until the 19th century, women (most of them neither educated nor with any kind of training, except that pertinent “to their nature”) were de iure mere characters of transition between the men who were holders of the business. One of the main causes of it were the normative obstacles which prevented or limited their development in any sphere of action: life, education, training and work, without forgetting the ideological discourses from the period. The aim of this doctoral thesis is to study the capacity to act of women who where holders of bookshops and printing or edition companies, having as a reference the case of Eulàlia Ferrer Montserrat (Brusi was her family name when married, 1780-1841): her activities in different fields, agencies and levels of action and how her professional identity was defined. Considering that the juridical capacity on the ownership of rights was posed as universal, the author deepens in her real capacity of acting that, due to the fact of being woman, restrained her juridical and legally, which defined a subordination and dependency which was in direct relation with her civil state.
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Chowdhury, Suvagata Roy [Verfasser], Thomas [Gutachter] Rudel, Joerg [Gutachter] Wischhusen, and Ana [Gutachter] Eulalio. "The Role of MicroRNAs in \(Chlamydia\) Infection / Suvagata Roy Chowdhury ; Gutachter: Thomas Rudel, Joerg Wischhusen, Ana Eulalio." Würzburg : Universität Würzburg, 2018. http://d-nb.info/1170061591/34.
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Herron, Joshua R. "Application of ALE contact to Composite Shell Finite Element model for Pneumatic Tires." University of Toledo / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1115217605.
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Ahmed, Mohammed Awad Eltoum. "A retrospective study of patients with biologics treatment at Groote Schuur and Red Cross Children's War Memorial Hospitals." Master's thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32432.
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Introduction. The high cost and concern of adverse events, particularly infections, limit the use of biologic disease-modifying anti-rheumatic (bDMARD) therapies. We undertook this retrospective study to document their use for immune-mediated diseases (IMDs) and explore the efficacy, safety, adherence and screening practices prior to initiating bDMARDs in a tertiary referral hospital. Methods. A folder review of all adult and paediatric patients treated for IMDs with bDMARDs at Groote Schuur and Red Cross Hospitals between January 2013 and December 2019. Clinico-demographic particulars, details of bDMARD therapy, and adverse events were collated. Changes in disease activity were measured by diseasespecific tools at 6, 12, 24-months and at the last available visit, and patient adherence to bDMARDs was explored by folder and pharmacy record review. Results. We studied 151 folders, with 182 bDMARDs uses (29 patients used more than 1 bDMARD). Patients were from rheumatology (n= 38: 13 rheumatoid arthritis; 10 spondyloarthritis, 5 Systemic Lupus Erythematosus (SLE) , 5 inflammatory myositis and 5 other conditions); gastroenterology (n=31; 26 Crohn`s and 5 Ulcerative Colitis), dermatology (n=9; psoriasis), neurology (n=4, ophthalmology (n= 25; 6 scleritis, 18 uveitis, 1 optic neuritis), and paediatrics (n= 45, 26 juvenile idiopathic arthritis , 12 SLE, 7 other conditions). The bDMARDs used were TNF inhibitors (112), rituximab (55), tocilizumab (10), anakinra (3), abatacept (1), and tofacitinib (1). The vast majority of patients had an excellent response and were in low disease activity or remission at their last available visit. Adverse events included severe infection (4), tuberculosis (TB) (2), mild infection (4), severe allergic reaction (3), mild skin reaction (14), elevated liver enzymes (2), and worsening interstitial lung disease ILD (1). bDMARD Therapy was discontinued in 18 patients, most commonly due to adverse reaction (9), lack of response (3), poor adherence (2), or remission (1). bDMARD Therapy was changed to alternative therapy in 29 patients, most commonly because of poor response (14), or adverse effects (9) or poor adherence (3). Poor adherence or patients lost to follow-up was noted in 18/182 (9.9%). Complete latent TB infection screening with chest x-ray and TB skin test was performed in only 55 (36.4 %) but INH prophylaxis was given to 51/88 (57.9%) of patients prescribed TNFi therapy. Hepatitis B screening performed in 93 (61.6 %) patients, but most patients (72.2 %) were not tested for Hepatitis B core ab. Hepatitis C screening was performed in 81 (53.6 %) patients. Only 88 (58.3%) patients had a recent HIV test. The majority (17.2%) received the influenza vaccine, but only 24 (15.8 %) received pneumococcal vaccination. Discussion and Conclusion. bDMARD therapy was an effective treatment, and the most common adverse effect was infection (7.2%), with 2 TB infections. Vaccination and screening for TB, viral hepatitis and HIV was suboptimal. Of concern, poor adherence to bDMARDs was frequently encountered.
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Hill, Caroline. "Art versus Propaganda?: Georgia Douglas Johnson and Eulalie Spence as Figures who Fostered Community in the Midst of Debate." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555276218786986.
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Carcenac, Antoine-Régis. "La Commanderie du Temple de Sainte Eulalie de Larzac : recherche d'histoire économique et sociale milieu XIIe-début XIVe siècle." Toulouse 2, 1987. http://www.theses.fr/1987TOU20083.
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Appuyee sur une solide assise fonciere, la commanderie de sainte eulalie a exerce une veritable domination sur le plateau du larzac et les regions voisines. Dans un pays essentiellement rural, elle a contribue a developper l'elevage ovin en vue de la production laitiere et de l'industrie fromagere. Les hommes sont surtout des paysans, domines par une aristocratie riche et puissante qui a favorise la progression de l'ordre du templeWith a strong landed foundation, the sainte eulalie's commandery exercised a real domination on the larzac and the arounding area. In a mostly rural country, sainte eulalie contributed to develop the sheep-farming with a view to the milk production and to the cheese industry. The men are mostly peasants, dominated by a rich and powerful aristocracy, that have favorized the progression of the temple order
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Yakabi, Bedriñana Katiusca Susana. "Integrando dimensiones para la comprensión del proceso de abandono de los sistemas de andenería de la comunidad campesina de San Juan de Iris, subcuenca Santa Eulalia, Huarochirí." Master's thesis, Pontificia Universidad Católica del Perú, 2017. http://tesis.pucp.edu.pe/repositorio/handle/123456789/9289.
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The present research, "Integrating dimensions for the understanding of the abandonment
process of highland terracing systems of the rural community of San Juan de Iris, Santa Eulalia
sub–basin, Huarochirí" has as general objective to analyze articulately physical, social,
economic, productive and institutional factors that lead to the abandonment of the highland
terracing systems. The integrated understanding of the problematic is the base to propose
recommendations for a productive system that contributes to the sustainable development of
the community, as well as to the conservation and enhancement of its agricultural terraces.
In order to achieve this objective, the methodology was organized in three phases in which
instruments of different sciences, such as soil science, geography and anthropology, were
applied to collect qualitative and quantitative information. The first phase consisted in a revision
of bibliographical, statistical and cartographical information, as a basis for the research
approach and the methodology itself. In the fieldwork, soil samples of the platforms were taken,
and quantitative information and perception were collected through surveys, interviews and a
workshop. Finally, in the third phase, precipitation data was acquired with the subsequent
calculation of interannual variability, the physical and chemical properties of the sampled soil
were analyzed and interpreted, the information obtained from the surveys, interviews and
workshop were systematized and the analysis was made. Applying a participatory approach, the
rural community of San Juan de Iris was involved throughout the investigation to be an active
part of the process.
The highland terracing system studied belongs to the rural community of San Juan de Iris, in the
district of the same name, located in left margin of the upper part of the Santa Eulalia sub–
basin, Huarochirí, in the Andean zone of Lima. In the 1990s, this community was benefited from
a rehabilitation experience of the National Program for Watershed Management and Soil
Conservation (PRONAMACHCS, for its acronym in Spanish); nevertheless, at the present time,
59.7% of its terracing systems are in a situation of abandonment. For this reason, this
community was chosen as the case study.
Field verification carried out by PRONAMACHCS indicates that the abandonment of terraces in
San Juan de Iris was in an 80% due to the water deficit (natural factor) and 20% to the migration
from the countryside to the city (social factor). However, the Andean rural reality is much more
complex; therefore, physical, institutional, economic-productive, and social dimensions of the
territory were explored in the research. The main drivers of the abandonment of the San Juan
de Iris terracing systems were the search for generating economic power (economic-productive
factor); migration of young people and adults (social factor); perception of decrease and lack of
water resources (physical-natural factor); change in the regime of the land tenure (institutional
factor); and dependence on projects and programs of external agents (socio-institutional factor).
With the main drivers of the abandonment process of the terracing systems identified, it is
possible to propose the actions in order to eliminate the causes of the problem. Otherwise, the
consequences derived from the abandonment process will intensify: underutilization of the soil
resource and food insecurity; increasing pressure on the natural pasture ecosystem that leads
to a risk in the profitability of livestock; loss of ancestral technique and knowledge; and lack of
initiative for the conservation of their agricultural terraces and for the development of the
community.
As a solution strategy is proposed to position the highland terraces as key element in the
development of the rural community of San Juan de Iris. For this, the agriculture on terraces
must respond to the expectations of the community, so that by their own and shared initiative,
they will include this productive and cultural resource in their vision of development.Tesis
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Álvarez, Grijalva Edith, Moscoso Guillermo Paul Quiroz, and Vega Ruddy Armando Villanueva. "Participación eficaz del sector defensa ante la ocurrencia del fenómeno del Niño Costero y su impacto en la atención a la población del Distrito de Santa Eulalia." Master's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/625982.
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El presente trabajo de investigación tuvo como objetivo, determinar la influencia de la participación eficaz del sector defensa, ante la ocurrencia del fenómeno del niño costero, en la atención a la población del distrito de Santa Eulalia.
Respecto a los aspectos metodológicos del trabajo, el tipo de investigación fue el aplicado y el nivel explicativo.
La población estuvo conformada por los 11,800 pobladores del distrito de Santa Eulalia.
La muestra estuvo conformada por 373 pobladores del distrito de Santa Eulalia, a los cuales se les aplicó el instrumento que constó de 18 preguntas, utilizando la escala de likert con alternativas de respuesta múltiple.
Se procedió a analizar los resultados, luego se realizó la contrastación de hipótesis, utilizando la prueba estadística conocida como coeficiente de correlación de SPEARMAN, debido a que las variables de estudio son cualitativas.
Finalmente, se pudo determinar que la participación eficaz del sector defensa ante la ocurrencia del fenómeno del niño costero influye significativamente en la atención a la población de Santa Eulalia.The objective of this research was to determine the influence of the effective participation of the defense sector, in the face of the occurrence of the phenomenon of the coastal child, in the attention to the population of Santa Eulalia. Regarding the methodological aspects of the work, the type of research was the applied and the explanatory level. The population was conformed by the 11,800 settlers of the district of Santa Eulalia. The sample was conformed by 373 settlers of the district of Santa Eulalia, To which the instrument was applied that consisted of 18 questions, using the scale of likert with alternatives of multiple answer. We proceeded to analyze the results, then we tested the hypothesis, using the statistical test known as the SPEARMAN correlation coefficient, because the study variables are qualitative. Finally, it was possible to determine that the effective participation of the defense sector in the face of the occurrence of the phenomenon of the coastal child significantly influences the attention to the population of Santa Eulalia.
Trabajo de investigación
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Carcenac, Antoine-Régis. "La Commanderie du temple de Sainte Eulalie de Larzac recherche d'histoire économique et sociale, milieu 12e-début du 14e siècle /." Lille 3 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37603612r.
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Zainol, Mohd Remy Rozainy Bin Mohd Arif. "A STUDY ON PARTICLE SEGREGATION PROCESSES IN DEBRIS FLOW BY AN EULAR-LAGRANGIAN COUPLED HYDRAULIC MODEL." 京都大学 (Kyoto University), 2012. http://hdl.handle.net/2433/157560.
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Serrano, Érica Vieira. "Adaptação transcultural do Eular Sjögren s Syndrome Disease Activity Index(ESSDAI) para a Língua Portuguesa Brasileira." Universidade Federal do Espírito Santo, 2012. http://repositorio.ufes.br/handle/10/5494.
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Previous issue date: 2012-11-05Introdução: O EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) é um índice composto para avaliar a atividade sistêmica da Síndrome de Sjögren primária (SSP), criado em 2009 na língua inglesa, ainda sem adaptação cultural para a língua portuguesa. Objetivo: Realizar a adaptação transcultural do ESSDAI para a língua portuguesa brasileira. Método: Estudo observacional transversal de pacientes com SSP classificados de acordo com o consenso europeu-americano de 2002. No processo de adaptação transcultural, foram realizadas seis etapas: equivalência conceitual, de item, semântica, operacional, de mensuração e funcional. A equivalência semântica incluiu a tradução, a retrotradução (back translation), avaliação da semântica entre as retrotraduções e o original, a discussão com especialistas para ajustes finais e o pré-teste da versão consensual em vinte pacientes. Na equivalência de mensuração, as propriedades psicométricas de consistência interna, reprodutibilidade interobservador e validade de constructo foram avaliadas em 62 indivíduos. Para a validade de constructo, o ESSDAI foi comparado com a avaliação global do médico (PhGA), o Sjögrens Syndrome Disease Activity Index (SSDAI), o Sjögren's Systemic Clinical Activity Index (SCAI), entre grupos ativo e inativo definidos por um especiatista e segundo a intenção de tratar nos grupos aumento de terapia e sem aumento de terapia. Os testes estatísticos utilizados foram o α de Cronbach para consistência interna, o coeficiente de correlação intraclasse e o método de Bland Altman para a reprodutibilidade interobservador, e o coeficiente de Spearman e teste de Mann-Whitney para a validade (p <0,05 e IC: 95%). Resultados: Não houve diferenças nas versões nas duas línguas, obtendo-se a versão consensual brasileira. A amostra foi constituída por mulheres, com idade de 49,4 ± 11,6 anos. O início dos sintomas foi de 7,2 ± 5,4 anos, e o tempo de diagnóstico foi de 3,0 ± 3,3 anos. A pontuação média do escore total do ESSDAI foi de 4,95 ± 6,73. Frequência de domínios foi de 40,3% biológico, 40,3% hematológico, 27,4% articular, 14,5% respiratório, 11,3% sistema nervoso periférico, 9,7% constitucional, 8,1% renal, 8,1% glandular, 4,8% pele e 1,6% linfadenopatia. Domínios do sistema nervoso central e os músculos foram zero em todos os pacientes. A consistência interna foi baixa, e a reprodutibilidade interobservador do ESSDAI obteve um forte coeficiente de correlação intraclasse de 0,89 e boa concordância pelo método de Bland Altman. Na validade de constructo, apresentou forte coeficiente de Spearman de 0,83 (p <0,000) com o PhGA, moderado com o SSDAI, com valor de 0,658 (p<0,000), e fraco com o SCAI, com valor de 0,411 (p=0,001). O Teste de Mann-Whitney mostrou que o grupo ativo e o grupo com aumento de terapia obtiveram maiores valores de ESSDAI (p = 0,000). Conclusão: A versão em português do ESSDAI mostrou ser um instrumento adaptável, reprodutível e válido para a língua portuguesa e pode ser usada no contexto brasileiro.
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Serrano, érica Vieira. "Adaptação transcultural do EULAR Sjögren/ s syndrome disease activity index (ESSDAI) para a língua portuguesa brasileira." Universidade Federal do Espírito Santo, 2012. http://repositorio.ufes.br/handle/10/5677.
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Previous issue date: 2012-11-05Introduction: The EULAR Sjögren s Syndrome Disease Activity Index (ESSDAI) is a composite index to assess systemic activity of primary Sjögren s Syndrome (SSP) created in 2009 and it does not have any cultural adaptation to Portuguese language. Objective: To perform the cultural adaptation of ESSDAI for Brazilian Portuguese. Methods: Cross-sectional observational study with patients with SSP according to the European American Consensus 2002. In the adaptation process, there were six steps: conceptual equivalence, item, semantic, operational, measurement and functional. Semantic equivalence included translation, back translation, evaluation of semantics between the original and back translations, discussion with experts for final adjustments and pre-test of consensual version in twenty patients. In measurement equivalence, the psychometric properties of internal consistency, interobserver reproducibility and construct validity were assessed in 62 subjects. For the construct validity, the ESSDAI was compared with the Physician s Global Assessment (PhGA), the Sjögren s Syndrome Disease Activity Index (SSDAI), the Sjögren s Systemic Clinical Activity Index (SCAI), between groups "active" and "inactive" defined by expert and according to intention to treat, the groups "increase therapy" and "no increase in therapy." Statistical tests used were Cronbach s α for internal consistency, the intraclass correlation coefficient and Bland Altman analysis for interobserver reproducibility, and the Spearman coefficient and Mann-Whitney test for validity (p <0.05 and CI: 95%). Results: There were no differences in the versions in both languages, giving the Brazilian consensual version. The sample consisted of women, aged 49.4 ± 11.6 years. The onset of symptoms was 7.2 ± 5.4 years and the time of diagnosis was 3.0 ± 3.3 years. The average score of the total score ESSDAI was 4.95 ± 6.73. Frequency domain was: 40.3% biological, 40.3% hematological, 27.4% articular, 14.5% respiratory, 11.3% peripheral nervous system, 9.7% constitutional, 8.1% renal, 8.1% glandular, 4.8% skin and 1.6% lymphadenopathy. Domains of the central nervous system and the muscles scored zero in all patients. Internal consistency was low and interobserver reproducibility of ESSDAI had a high intraclass correlation coefficient of 0.89 and good agreement by Bland Altman. In construct validity, the correlation with PhGA was 0.83 (p <0.000, Spearman coefficient), with SSDAI was 0.658 (p <0.000), and with SCAI was 0.411 (p = 0.001). Mann-Whitney test showed that the group "active" and the group "needed increased therapy" obtained the higher values in ESSDAI (p = 0.000). Conclusion: The Portuguese version of ESSDAI proved to be an adaptable instrument, reproducible and valid for Portuguese and can be used in the Brazilian context
Introdução: O EULAR Sjögren s Syndrome Disease Activity Index (ESSDAI) é um índice composto para avaliar a atividade sistêmica da Síndrome de Sjögren primária (SSP), criado em 2009 na língua inglesa, ainda sem adaptação cultural para a língua portuguesa. Objetivo: Realizar a adaptação transcultural do ESSDAI para a língua portuguesa brasileira. Método: Estudo observacional transversal de pacientes com SSP classificados de acordo com o consenso europeu-americano de 2002. No processo de adaptação transcultural, foram realizadas seis etapas: equivalência conceitual, de item, semântica, operacional, de mensuração e funcional. A equivalência semântica incluiu a tradução, a retrotradução (back translation), avaliação da semântica entre as retrotraduções e o original, a discussão com especialistas para ajustes finais e o pré-teste da versão consensual em vinte pacientes. Na equivalência de mensuração, as propriedades psicométricas de consistência interna, reprodutibilidade interobservador e validade de constructo foram avaliadas em 62 indivíduos. Para a validade de constructo, o ESSDAI foi comparado com a avaliação global do médico (PhGA), o Sjögren s Syndrome Disease Activity Index (SSDAI), o Sjögren s Systemic Clinical Activity Index (SCAI), entre grupos ativo e inativo definidos por um especiatista e segundo a intenção de tratar nos grupos aumento de terapia e sem aumento de terapia . Os testes estatísticos utilizados foram o α de Cronbach para consistência interna, o coeficiente de correlação intraclasse e o método de Bland Altman para a reprodutibilidade interobservador, e o coeficiente de Spearman e teste de Mann-Whitney para a validade (p <0,05 e IC: 95%). Resultados: Não houve diferenças nas versões nas duas línguas, obtendo-se a versão consensual brasileira. A amostra foi constituída por mulheres, com idade de 49,4 ± 11,6 anos. O início dos sintomas foi de 7,2 ± 5,4 anos, e o tempo de diagnóstico foi de 3,0 ± 3,3 anos. A pontuação média do escore total do ESSDAI foi de 4,95 ± 6,73. Frequência de domínios foi de 40,3% biológico, 40,3% hematológico, 27,4% articular, 14,5% respiratório, 11,3% sistema nervoso periférico, 9,7% constitucional, 8,1% renal, 8,1% glandular, 4,8% pele e 1,6% linfadenopatia. Domínios do sistema nervoso central e os músculos foram zero em todos os pacientes. A consistência interna foi baixa, e a reprodutibilidade interobservador do ESSDAI obteve um forte coeficiente de correlação intraclasse de 0,89 e boa concordância pelo método de Bland Altman. Na validade de constructo, apresentou forte coeficiente de Spearman de 0,83 (p <0,000) com o PhGA, moderado com o SSDAI, com valor de 0,658 (p<0,000), e fraco com o SCAI, com valor de 0,411 (p=0,001). O Teste de Mann-Whitney mostrou que o grupo ativo e o grupo com aumento de terapia obtiveram maiores valores de ESSDAI (p = 0,000). Conclusão: A versão em português do ESSDAI mostrou ser um instrumento adaptável, reprodutível e válido para a língua portuguesa e pode ser usada no contexto brasileiro
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Tawk, Caroline S. [Verfasser], Jörg [Gutachter] Vogel, Utz [Gutachter] Fischer, and Ana [Gutachter] Eulalio. "The role of host-stress in the infection by the bacterial pathogen \(Shigella\) \(flexneri\) / Caroline S. Tawk ; Gutachter: Jörg Vogel, Utz Fischer, Ana Eulalio." Würzburg : Universität Würzburg, 2018. http://d-nb.info/1161671412/34.
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ZANETTI, ANNA. "The management of patients with rheumatoid arthritis: an overview of obstacles and improvement strategies." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2022. http://hdl.handle.net/10281/365542.
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L’artirite reumatoide (AR) è la più diffusa patologia autoimmune in Italia con elevati costi terapeutici e previdenziali associati. Questa patologia colpisce circa lo 0.5-1% della popolazione adulta, prevalentemente di genere femminile. Essendo una patologia degenerativa, i cui danni sono frequentemente irreversibili, una diagnosi precoce così come un adeguato trattamento ed un elevato livello di compliance del paziente allo stesso, potrebbero rallentare il peggioramento della malattia. Inoltre sono poco noti i possibili effetti della malattia e del suo trattamento sulle gravidanze e i successivi outcome gravidici. I principali obiettivi della tesi quindi sono: i) valutare l’aderenza alle linee guida per il trattamento dell’ AR da parte dei clinici, ii) valutare l’aderenza al trattamento per AR da parte del paziente, iii) stimare costo ed efficacia delle cure erogate nelle cliniche specializzate per il trattamento di pazienti con AR, iv) analizzare gli esiti gravidici e il raggiungimento della gravidanza in donne con AR trattate con metotrexate (MTX). La prima tematica ha riguardato la valutazione di come sono state implementate le linee guida della European Alliance of Associations for Rheumatology (EULAR) per il trattamento dell’AR e l’impatto dell’aderenza a queste linee guida sulla probabilità di ospedalizzazione. I principali risultati di questo studio hanno mostrato come i pazienti con un’ottima aderenza alle linee guida, se confrontati con quelli con bassa aderenza, abbiano un rischio del 24% inferiore di incorrere in ospedalizzazione. La seconda tematica ha riguardato la valutazione dell’impatto dell’aderenza al trattamento con Disease-Modifying Anti-Rheumatic Drugs (DMARDs), terapia suggerita dall’EULAR, sul raggiungimento della remissione clinica di malattia. I dati provengono dal database ELECTRA (con informazioni cliniche e provenienti da database amministrativi) di pazienti con AR trattati presso l’IRCCS Policlinico San Matteo (Pavia). Si è osservato che un incremento percentuale di 10 unità nella copertura al trattamento comporta un aumento della probabilità di remissione clinica del 10%. Da questi risultati sembra emergere l’importanza di riuscire a monitorare i pazienti nella pratica clinica per mantenere elevati standard di compliance. L’obiettivo della terza tematica si è focalizzato su una valutazione costo-efficacia del trattamento dei pazienti con AR erogato da cliniche specializzate (EAC), confrontandolo con quello dei pazienti trattati in cliniche non specializzate. Sono state quindi reclutate due coorti, la prima di pazienti trattati in una EAC e l’altra estratta dai database amministrativi di regione lombardia tra i soli soggetti con AR. I risultati principali di questa terza fase hanno mostrato come ad un incremento moderato dei costi si associ un incremento molto elevato dell’efficacia, specialmente se calcolata come durata di degenza e come aderenza alle linee guida EULAR. La quarta ed ultima tematica riguarda l’analisi dell’impatto del trattamento con MTX (DMARD suggerito dall’EULAR come prima linea di trattamento) nelle pazienti con AR sulla possibilità di raggiungere una gravidanza e sugli outcome gravidici conseguenti. Sono state definite tre coorti: donne con AR con esposizione incidente di MTX, donne con AR senza trattamento con MTX e donne senza AR. I risultati principali di questa analisi hanno mostrato che le donne con AR, specialmente se trattate con MTX, hanno una minor frequenza di gravidanze rispetto alle donne senza AR. Inoltre, le donne trattate con MTX sembrano avere un rischio più elevato di aborto spontaneo (circa due volte superiore) rispetto alle altre due coorti.Rheumatoid arthritis (RA) is, in Italy, the most widespread autoimmune disease with high associated costs for the National Health Service. This disease affects about 0.5-1% of the adult population, mainly of the female gender. Being a degenerative disease, whose damages are frequently irreversible, an early diagnosis as well as an adequate treatment and a high level treatment compliance of the patient, could slow down the worsening of the disease. Furthermore, the possible effects of RA and its treatment on pregnancies and subsequent pregnancy outcomes are not well known. The main objectives of the thesis are therefore: i) to evaluate the adherence to guidelines for the treatment of RA, ii) to evaluate the patient's adherence to RA treatment, iii) to estimate the cost and effectiveness of care provided in specialized clinics for the treatment of RA patients, iv) to analyze pregnancy outcomes and the likelihood of achieving pregnancy in women with RA treated with methotrexate (MTX). The first issue concerned the assessment of how the guidelines of the European Alliance of Associations for Rheumatology (EULAR) for the treatment of RA have been implemented, and the impact of adherence to these guidelines on the probability of hospitalization. The main results of this study showed that patients with excellent adherence to guidelines, when compared with those with low adherence, have a 24% lower risk of hospitalization. The second topic concerned the evaluation of the impact of adherence to treatment with Disease-Modifying Anti-Rheumatic Drugs (DMARDs), the therapy suggested by EULAR, on the achievement of disease clinical remission (defined as a substantial decrease or absence of symptoms). The ELECTRA database, which contains clinical information and information from administrative databases of RA patients treated at the IRCCS Policlinico San Matteo (Pavia), was considered for the analysis. The main finding showed that a 10-unit percentage increase in proportion of days covered by DMARDs is associated with a 10% increase in the likelihood of clinical remission. These results show the importance of monitoring patients in clinical practice to maintain high levels of treatment compliance. The objective of the third theme focused on a cost-effectiveness evaluation, comparing RA patients treated in specialized clinics ("Early Arthritis Clinic" - EAC), with RA patients treated in non-specialized clinics. Two cohorts were recruited, the first one included patients treated in the EAC of the IRCCS Policlinico San Matteo and the other one with patients with RA extracted from the administrative databases of Lombardy region. The main results of this third phase showed that a moderate increase in costs is associated with a very high increase in effectiveness, especially if calculated as length of hospitalizations and as adherence to the EULAR guidelines. These findings could open up new scenarios in RA patient management. The fourth and final topic concerned the impact of treatment with MTX (DMARD suggested by EULAR as the first line of treatment) in RA women, on the likelihood of achieving pregnancy and on pregnancy outcomes. Three cohorts were recruited: women with RA with incident MTX exposure, women with RA without MTX treatment, and women without RA. The main results of this analysis showed that women with RA, especially when treated with MTX, have a lower frequency of pregnancies than women without RA. Furthermore, women treated with MTX have a higher risk of spontaneous abortion (about twice as high) than the other two cohorts.
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Johnson, Penny. "Eulalie de Mandeville: An Ethnohistorical Investigation Challenging Notions of Placage in New Orleans as revealed through The Lived Experiences of a Free Woman of Color." ScholarWorks@UNO, 2010. http://scholarworks.uno.edu/td/1285.
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This ethnohistorical work investigates plaçage through the case of Eulalie de Mandeville, a free woman of color and both the daughter of Pierre de Marigny de Mandeville, one of the largest land owners in New Orleans, and the sister of Bernard Marigny, land owner and founder of the Faubourg Marigny, a historic neighborhood in New Orleans. Eulalie's connection to the de Marigny de Mandeville family led to gifts of money and real estate from Pierre, Bernard, and her grandmother, Madame de Mandeville. She used these gifts to not only secure financing for a successful retail business, but also to finance her plaçage partner's loan brokerage business and to become one of the wealthiest women in New Orleans. Eulalie's case helps create a context for the free woman of color that challenges the images presented in much of the literature to date, bringing her down from the heights of romanticism into the realm of reality. This is her story.
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Vasquez, Ospina Juan Jose [Verfasser], Tim Nicolai [Gutachter] Siegel, Christian [Gutachter] Janzen, Ana [Gutachter] Eulalio, and Sandra [Gutachter] Hake. "Development of tools for the study of gene regulation in Trypanosoma brucei / Juan Jose Vasquez Ospina. Gutachter: Tim Nicolai Siegel ; Christian Janzen ; Ana Eulalio ; Sandra Hake." Würzburg : Universität Würzburg, 2016. http://d-nb.info/111204115X/34.
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Linn, Rachel E. "Pieces of the Body, Shards of the Soul: The Martyrs of Erik Ehn." Ohio University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1427822605.
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Silva, Otávio Lino e. "Análises filogeográficas de Exaerete smaragdina (Guérin-Méneville, 1845) (Hymenoptera, Apidae, Euglossini) e sua hospedeira Eulaema nigrita (Lepeletier, 1841) (Hymenoptera, Apidae, Euglossini) e o status de Exaerete lepeletieri (Oliveira & Nemésio, 2003)." Universidade Federal de São Carlos, 2009. https://repositorio.ufscar.br/handle/ufscar/5463.
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Previous issue date: 2009-07-07Universidade Federal de Sao Carlos
A tribo Euglossini possui cerca de 200 especies de abelhas descritas, distribuidas em cinco generos considerados monofileticos. Os generos Exaerete e Aglae apresentam comportamento cleptoparasita, atacando outras especies de Euglossini. Para a especie Exaerete smaragdina, os unicos relatos na literatura referem-se ao parasitismo de Eulaema nigrita. Porem, ha indicios de que esta nao seja sua unica hospedeira. Desta forma, a filogeografia destas duas especies foi comparada, com o intuito de analisar se ha concordancia entre as suas historias evolutivas, pois, quanto maior a obrigatoriedade da relacao parasitahospedeiro, mais congruente espera-se que sejam suas filogeografias. Para Ex. smaragdina, foram observadas populacoes estruturadas geograficamente e os testes de neutralidade nao foram significantes. Para El. nigrita, nao foi observada estruturacao populacional, havendo uma baixa variabilidade genetica e a maioria das populacoes compartilhando um mesmo haplotipo. Estes dados, associados a testes de neutralidade estatisticamente significantes, indicam que as populacoes desta especie sofreram uma expansao populacional recente. A comparacao dos padroes filogeograficos indica ainda que El. nigrita nao deva ser a unica hospedeira de Ex. smaragdina. Tambem foi analisado o status de especie da Exaerete lepeletieri, considerada recentemente uma sinonimia de Ex. frontalis. Os resultados indicam que Ex. lepeletieri apresenta monofilia para o loco 16S, enquanto dois clados foram observados para o loco Citocromo B (CytB).
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Xie, Jing. "Simulation of cold spray particle deposition process." Thesis, Lyon, INSA, 2014. http://www.theses.fr/2014ISAL0044/document.
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La projection à froid est une technologie en plein essor pour le dépôt de matériaux à l'état solide. Le procédé de dépôt des particules par pulvérisation à froid est simulé par la modélisation de l'impact à haute vitesse de particules sphériques sur un substrat plat dans diverses conditions. Pour la première fois, nous proposons une approche numérique par couplage Euler-Lagrange (CEL) afin de résoudre ce problème à haute vitesse de déformation. Les capacités de l'approche numérique CEL pour la modélisation du processus de dépôt de projection à froid sont évaluées par une étude paramétrique de : la vitesse d'impact, la température initiale des particules, le coefficient de frottement et le choix des matériaux. Les résultats de la simulation à l'aide de l'approche numérique CEL sont en accord avec les résultats expérimentaux publiés dans la littérature. La méthode CEL est généralement plus précise et plus robuste dans des régimes de déformations élevées. Un nouveau modèle d'empilement de type CFC, inspiré de la structure cristalline, est construit afin d'étudier le taux de porosité des particules déposées et les contraintes résiduelles dans le matériau de substrat pour diverses conditions. Nous pouvons observer non seulement la géométrie 3D de porosités, mais aussi leur répartition et leur évolution pendant les impacts successifs. Pour les particules, une vitesse d'impact et une température initiale élevées, sont des avantages pour produire des revêtements denses par projection à froid. Des contraintes résiduelles de compression existent à l'interface entre les particules et le substrat. Ces dernières sont causées par les grandes amplitudes et vitesses de déformation plastique induites par le procédé. Un second modèle moins complexe pour la modélisation de l'impact multiple oblique a été créé afin de simuler l'érosion de surface. Une forte érosion de surface est le résultat : d'une plus grande vitesse d'impact, d'un coefficient de frottement élevé et d'un angle de contact réduite. Pour un matériau ductile comme le cuivre, il y a deux modes de rupture : le mode 1 de traction et le mode 2 de rupture par cisaillement. Le premier survient principalement en dessous de la surface du substrat et à la périphérie de impacts, tandis que le second intervient de manière prédominante à la surface des impacts. On observe quatre étapes lors de la propagation des fissures : la formation de porosités, de fissures, la croissance de ces dernières, puis une dernière étape de coalescence et rupture. Un critère simple, où la vitesse d'érosion est fonction de l'angle de contact et de la vitesse critique d'érosion lors d'un impact de vitesse normale , est proposé sur la base des résultats des simulations afin de prédire l'initiation de l'endommagement. La déformation plastique équivalente est également un paramètre clef pour identifier l'initiation de l'endommagement, une valeur critique de 1,042 a été trouvée dans notre étude pour le cuivreCold spray is a rapidly developing coating technology for depositing materials in the solid state. The cold spray particle deposition process was simulated by modeling the high velocity impacts of spherical particles onto a flat substrate under various conditions. We, for the first time, proposed the Couple Eulerian Lagrangian (CEL) numerical approach to solve the high strain rate deformation problem. The capability of the CEL numerical approach in modeling the Cold Spray deposition process was verified through a systematic parameter study, including impact velocity, initial particle temperature, friction coefficient and materials combination. The simulation results by using the CEL numerical approach agree with the experimental results published in the literature. Comparing with other numerical approaches, which are Lagrangian, ALE and SPH, the CEL analyses are generally more accurate and more robust in higher deformation regimes. Besides simulating the single particle impact problem, we also extended our study into the simulation of multiple impacts. A FCC-like particles arrangement model that inspired by the crystal structure was built to investigate the porosity rate and residual stress of deposited particles under various conditions. We observed not only the 3D profiles of voids, but also their distributions and developments during different procedures. Higher impact velocity and higher initial temperature of particles are both of benefit to produce a denser cold spray coating. The compressive residual stresses existed in the interface between the particle and substrate is mainly caused by the large and fast plastic deformation. Another simplified model for multiple impacts was created for the simulation of surface erosion. A severe surface erosion is the result of a high impact velocity, a high friction coefficient and a low contact angle. Two element failure models suitable for high-strain-rate dynamic problems were introduced in this study. For a ductile material as Copper, it followed two fracture modes in our study, which are tensile failure mode and shear failure mode. The former one mainly occurred beneath the substrate surface and the periphery of substrate craters, nevertheless the latter one was found predominately at the surface of craters. Four steps were found during the propagation of crack: void formation; crack formation; crack growth; coalescence and failure. A simple criterion equation was derived based on the simulation results for predicting the initiation of damage, which the erosion velocity v_{ero} is a function of contact angle and erosion velocity for normal impact v_{pi/2}. The equivalent plastic strain could also be a parameter for identifying the onset of damage, identified as being 1.042 for Copper in our study
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Bonetto, Alexis. "Etude de l'indentation et de la fatigue des contacts roulants." Thesis, Lyon, 2020. http://www.theses.fr/2020LYSEI030.
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La fatigue de surface est aujourd'hui la principale cause de défaillances des roulements. Ce type de fatigue peut se développer du simple fait de la rugosité des surfaces mais est exacerbée par la présence de défauts de surface tels que les indents. La gestion de la pollution des lubrifiants, à l'origine de l'indentation des surfaces, est très coûteuse et ne peut être parfaite puisque la pollution est à la fois présente dans les huiles neuves, générée de manière continue par les systèmes lubrifiés et introduite lors des opérations sur le système. En conséquence, les huiles charrient systématiquement des particules d'origines variées qui sont amenées dans les contacts par les systèmes de lubrification. Au passage entre les surfaces, les particules sont écrasées et indentent les surfaces, créant ainsi des défauts qui seront les sites privilégiés d'amorçage de fatigue au cours des cycles de fonctionnement suivants. Ne pouvant se prémunir de l'indentation des surfaces, une bonne compréhension des mécanismes d'indentation et de fatigue sur indent est nécessaire pour garantir la fiabilité des roulements ainsi que pour réduire les coûts liés à leur maintenance. Au cours de cette thèse, un modèle éléments finis « couplé Euler-Lagrange » est développé pour reproduire le processus d’indentation réel des roulements et en étudier les effets. Dans un second temps, la fatigue des surfaces est étudiée par l’emploi de critères de fatigue issus de la littérature dans le cadre d’un contact sec. Enfin, l’effet du lubrifiant est ajouté par la mise en place d’un solveur multigrilles permettant la résolution du problème EHD transitoireSurface fatigue is currently the main cause of rolling element bearings failures. This type of fatigue can appear due to the presence of surface asperities but is exacerbated by the presence of surface defects such as dents. Handling the contamination of the lubricants that causes the denting of the surfaces is expensive and imperfect since the particles are not only already present in brand new oil but also generated during the operation of the system. Consequently, the lubricant carts particles of various nature into the contact. As they pass through the contact, the particles are crushed and dent the bearing surfaces, creating surface defects that will turn into initiation site for fatigue phenomena. As it is impossible to avoid debris denting, a better understanding of the denting and fatigue mechanisms is required to guarantee the reliability of the components and reduce their maintenance costs. During this PhD, a “coupled Euler-Lagrange” finite element model has been developed to reproduce the realistic debris denting process and study its effects. Then, the surface fatigue of dented surfaces was investigated using fatigue criteria in dry contact conditions. Finally, the effect of the lubricant on the dented surface was introduced using a multigrid solver for the transient EHL problem
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Veliz, Bertha M. "Learning from Andean vernacular architecture: a proposal for a tourist center in San Pedro de Casta, Marcahuasi." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/53111.
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The architectural intentions may best be described in the phrases: "symbolic meaning of the environment" - "the spirit of place" - and the need to assure the "historical continuity".
The main points of the program are the following:
1.- to create a service unit corresponding to the needs of the overall development of the micro-region as regards to tourism,
2.- to favor contact between the tourists and the local population,
3.- to express this aim by means of an open type of structure,
4.- to offer a wide range of activities corresponding to the needs and desires of the occupants,
5.- not to destroy the natural and existing environment.Master of Architecture
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NENCETTI, CATERINA. "La «vicenda» di Aurelia ed Eularia. Vite in scena di Brigida Fedeli ed Orsola Cortesi tra le piazze italiane e la Comédie Italienne." Doctoral thesis, 2016. http://hdl.handle.net/2158/1028452.
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Tesi di ricerca sulla biografia, la carriera e le opere di Brigida Fedeli (in arte Aurelia) ed Orsola Cortesi (in arte Eularia), attrici attive tra le piazze teatrali italiane e quelle francesi nel corso del Seicento.
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Mateo, Toledo Eladio. "The family of complex predicates in Q'anjob'al (Maya) : their syntax and meaning." 2008. http://hdl.handle.net/2152/18289.
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This dissertation describes six syntactic complex predicates in Q'anjob'al (Maya) spoken in Santa Eulalia, Huehuetenango, Guatemala: the Directional Construction (DIRC), Verbal Resultative Predicate (resultative V1V2), Causative Predicate (causative V1V2), Complement-like Predicate (complement-like V1V2), Preverbal Resultative Predicate (R2°P), and Positional Resultative Construction (PRC). They resemble resultatives, serial verbs, and causatives in other languages. The dissertation describes their monoclausal structure, meaning, event and argument structure, and lexical restrictions. These translate into five parameters: (a) they have a single value of time, aspect, modality and polarity, (b) they have a single set of arguments, (c) they have one intonational contour, (d) the elements denote a single event or subparts of a macro event, and (e) the elements minimally involve argument sharing, but could also involve argument fusion, or composition. Q'anjob'al complex predicates have two main features: (a) they are of an asymmetric type in that one element functions as the 'primary' element, and (b) they always have a verbal element (V) with another element that can be verbal or nonverbal (NV). Thus, these complex predicates always have a verbal 'primary' element. Regarding their structure, complex predicates involve four constructions: (a) a nonverbal-verbal construction used by the R2°P and shared by depictives (where it is a non-complex predicate and multi-headed clause), (b) a verb-verb construction used for causative, resultative, and complement-like V1V2s and shared by DIRCs, (c) a verbdirectional construction, a serial verb type, where V is the main verb and DIR corresponds to up to three motion verbs, and (d) a verb-positional construction used by the PRC. In their argument structure, resultatives and causative V1V2s, PRCs, and R2°Ps involve argument fusion, complement-like V1V2s involve raising, and DIRCs may involve argument sharing or fusion depending on the particular type. Regarding event structure, resultative V1V2s, and aspectual DIRCs denote a single event, and other complex predicates denote macro events. Finally, lexical semantics is central for distinguishing complex predicates from each other and from other multi-headed clauses. This dissertation contributes to the documentation of Q'anjob'al and advances the syntactic and semantic analysis of Mayan languages. It also contributes to our understanding of complex predicates through a case study.text
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Santos, Maria Leonor Veríssimo dos. "A transcriptomic approach to the metabolism of porphyrin-like pigments in a marine Polychaeta (Eulalia sp.)." Master's thesis, 2020. http://hdl.handle.net/10362/114346.
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The last decade witnessed a growing interest on marine natural pigments for biotechnological and
biomedical applications. One of the most abundant naturally occurring pigments are the tetrapyrroles
which are prized targets due to their photodynamic properties. Their most notorious representatives are
porphyrins. Animal porphyrins result from the breakdown of heme and are known as bile pigments, the
best known of which are biliverdin and bilirubin. Because of their unique chemical structure, porphyrins
can have several applications such as photosensitizers in photodynamic therapy as well as antioxidants
or even antimicrobials. For such reasons, porphyrinoids are high-prized animal metabolites for
biomedical research. Naturally, abundant sources of these compounds, particularly those offering a
wide-variety of the compounds such as coastal marine invertebrates, yield high biotechnological
potential. The Polychaeta Eulalia sp. is known for its bright green coloration provided by the multiple
greenish and yellowish porphyrinoid pigments found in this worm, which turns this species into the
perfect case study since the chemistry and biosynthetic process of heme-derived pigments in
Polychaeta remains mainly unknown. The present study combined HPLC-DAD with a transcriptomic
approach (RNA-Seq) on the main tissues of Eulalia sp. displaying pigmentation, the proboscis and
epidermis, with the aim of understanding the diversity and origin of its complex pigmentation. The results
showed that the endogenous pigments of this worm are seemingly heme-derived and have the
necessary mechanism for conversion to bile pigments. Also, several protein variants of the heme
biosynthetic pathway were found in the two organs, indicating the possible production of diverse heme related products that can be then converted to products similar to biliverdin or bilirubin. The specific and
common variants found in both organs can explain the similar and different pigmentation patterns
between the proboscis and epidermis. Altogether, this species is indeed a prolific source of novel
porphyrinoids
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Ho, Ping-Huan, and 何秉寰. "Using the Moving Particle Method With Eularian Mesh toSolve Lid-Driven Cavity Flow Problem in Stream Function-vorticity Formulation." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/55603312173627893916.
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碩士國立高雄海洋科技大學
輪機工程研究所
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This study focused on applying the method of dual particles to solve the lid-driven cavity flow problem in stream function–vorticity formulation. The method of dual particles includes the Lagrangian particle which possesses the convection behavior, while another Eulerian particle does not have such flowing characteristic effect. Using the property of the Eulerian particle, a fixed grid framework can be constructed. This paper considered three different schemes to evaluate the diffusion effect occurring in Lagrangian particle. They are particle smoothing (PS), smoothing difference (SD) and local mesh (LM). The PS scheme is formulated by superimposing contribution from distributed particles; SD scheme by combining the PS and Taylor series analysis and LM is derived based on a referenced mesh. The numerical results obtained by using the dual particle method proposed in the present study of the lid-driven cavity flow problem for various Reynolds numbers indicated that the more accurate solutions are attained in the formulation of stream function-vorticity rather than the formulation in primitive variables, especially under very high Reynolds numbers. The resultant simulations are observed deviated from the reference data for coarse meshes, however, when fine meshes are adopted, the simulation results obtained are in good agreement with the literatures.
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Rodrigo, Ana Patrícia Carreira. "The biotechnological value of a novel potent marine biotoxin from the polychaete worm Eulalia viridis: chemical and toxicological evaluation." Doctoral thesis, 2020. http://hdl.handle.net/10362/116178.
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The ocean’s vastness holds still many unexplored organisms with unique adaptive features that enable them to thrive in their environment. Eulalia viridis is one of them. This uncanny bright green worm is a predatory marine Polychaeta of the rocky intertidal that lacks jaws, but it is equipped with a toxin-containing mucus that enables predating larger invertebrates from which soft tissue is extracted through suction. Motivated by the high-value of toxins as bioreactives and by the European Union’s ambitions of leading the Blue Growth Strategy, for which Portugal’s vast EEZ offers high perspectives; a case-study to explore the biotechnological potential of this species was undertaken. The worm’s microanatomy revealed key adaptations for feeding such as special sensorial papillae and cells responsible for the secretion of mucus and toxins. Whole-transcriptome sequencing and toxicity assays yielded a complex pattern of proteinaceous toxins and enzymes with several functions: tissue permeabilization, coagulation impairment and blocking of neuromuscular activity. The main neurotoxins, “phyllotoxins”, found to be cysteine-rich proteins, act as immobilising agents against mussels and other invertebrate prey and are delivered by contact with mucus. In turn, higher toxicity towards ovarian cancer cell line (A2780) than normal cells, involved cytotoxic and cytostatic properties through cell cycle arrest and extrinsic programmed cell death. Several proteins involved in these effects were identified by combining transcriptomics and proteomics. The worm’s mucosecretions also hold internalisable proteinaceous complexes that display fluorescent properties and whose emission is reversibly switched by redox status. Altogether, the features found in the secretions of a single species disclose the immense biotechnological potential of marine annelids, and invertebrates in general, as source of valuable bio-reactives, even in temperate waters. The methodological pipeline, combining ecology, toxicology and molecular biology, circumvented many difficulties of marine bioprospecting and is an important contribution for the sustainable exploitation of novel marine bioresources.O oceano contém muitos organismos por explorar com características adaptativas que os permitem prosperar no seu meio ambiente. Eulalia viridis é um desses organismos. Esta poliqueta verde clara é predador do intertidal rochoso sem mandibulas, equipado dum muco tóxico, permitindo assim predar invertebrados maiores extraindo pedaços de tecido através da sucção. Motivado pelo valor das toxinas como substâncias bioreactivas e pela ambição da UE de conduzir a Estratégia para o Crescimento Azul, à qual a vasta ZEE portuguesa oferece grandes perspetivas, o potencial biotecnológico desta espécie foi analisado. A análise microanatómica desta minhoca revelou adaptações cruciais na alimentação: existência de papilas sensoriais e células responsáveis pela secreção de muco e toxinas. A sequenciação completa do transcritoma e ensaios toxicológicos revelaram um complexo padrão de toxinas proteicas e enzimas com diversas funções: permeabilização de tecidos, anti-coagulação e bloqueio da atividade neuromuscular. As principais neurotoxinas da Eulalia, “filotoxinas”, são proteínas ricas em cisteínas, que atuam como agentes imobilizadores em mexilhões e outros invertebrados, que são administradas por contacto através do muco. Por sua vez, uma maior toxicidade para com a linha celular do cancro do ovário (A2780) do que células normais, demonstraram propriedades citotóxicas e citoestáticas através da paragem do ciclo celular e indução de morte celular programada pela via extrínseca. As proteínas responsáveis por estes efeitos foram identificadas, através de transcritómica e proteómica. As secreções mucosas da minhoca contêm também complexos proteicos internalizáveis que apresentam fluorescência, cuja emissão é reversivelmente regulada pelo estado redox. Resumindo, as características encontradas nas secreções de uma espécie demonstram o vasto potencial biotecnológico de anelídeos marinhos, como uma fonte valiosa de bioreactivos, mesmo em águas temperadas. O percurso metodológico utilizado, a combinação da ecologia, toxicologia e biologia molecular, permitiu contornar dificuldades da bioprospecção marinha, revelando ser um importante contributo para exploração sustentável de novos biorecursos marinhos.
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Powe, Norma Faye. "Sculpture of the cathedral cloister, Elne." 1989. http://catalog.hathitrust.org/api/volumes/oclc/21992299.html.
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Choudhury, Prasun. "Dynamics, Singularity And Controllability Analysis Of Closed-Loop Manipulators." Thesis, 1997. http://etd.iisc.ernet.in/handle/2005/2145.
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Haladuick, Tyler. "Numerical Simulation of Blast Interaction with the Human Body: Primary Blast Brain Injury Prediction." Thesis, 2014. http://hdl.handle.net/10012/8265.
Full textAbstract:
In Operations Enduring Freedom and Iraqi Freedom, explosions accounted for 81% of all injuries; this is a higher casualty percentage than in any previous wars. Blast wave overpressure has recently been associated with varying levels of traumatic brain injury in soldiers exposed to blast loading. Presently, the injury mechanism behind primary blast brain injury is not well understood due to the complex interactions between the blast wave and the human body. Despite these limitations in the understanding of head injury thresholds, head kinematics are often used to predict the overall potential for head injury. The purpose of this study was to investigate head kinematics, and predict injury from a range of simulated blast loads at varying standoff distances and differing heights of bursts.
The validated Generator of body data multi-body human surrogate model allows for numerical kinematic data simulation in explicit finite element method fluid structure interaction blast modeling. Two finite element methods were investigated to simulate blast interaction with humans, an enhanced blast uncoupled method, and an Arbitrary Lagrangian Eularian fully coupled method. The enhanced blast method defines an air blast function through the application of a blast pressure wave, including ground reflections, based on the explosives relative location to a target; the pressures curves are based on the Convention Weapons databases. LBE model is efficient for parametric numerical studies of blast interaction where the target response is the only necessary result. The ALE model, unlike classical Lagrangian methods, has a fixed finite element mesh that allows material to flow through it; this enables simulation of large deformation problems such as blast in an air medium and its subsequent interaction with structures. The ALE model should be used when research into a specific blast scenario is of interest, since this method is more computationally expensive. The ALE method can evaluate a blast scenario in more detail including: explosive detonation, blast wave development and propagation, near-field fireball effects, blast wave reflection, as well as 3D blast wave interaction, reflection and refraction with a target.
Both approaches were validated against experimental blast tests performed by Defense Research and Development Valcartier and ConWep databases for peak pressure, arrival time, impulse, and curve shape. The models were in good agreement with one another and follow the experimental data trend showing an exponential reduction in peak acceleration with increasing standoff distance until the Mach stem effect reached head height. The Mach stem phenomenon is a shock front formed by the merging of the incident and reflected shock waves; it increases the applied peak pressure and duration of a blast wave thus expanding the potential head injury zone surrounding a raised explosive. The enhanced blast model was in good agreement with experimental data in the near-field, and mid-field; however, overestimated the peak acceleration, and head injury criteria values in the far-field due to an over predicted pressure impulse force. The ALE model also over predicted the response based on the head injury criteria at an increased standoff distance due to smearing of the blast wave over several finite elements leading to an increased duration loading.
According to the Abbreviated Injury Scale, the models predicted a maximal level 6 injury for all explosive sizes in the near-field, with a rapid acceleration of the head over approximately 1 ms. There is a drastic exponential reduction in the insult force and potential injury received with increasing standoff distance outside of the near-field region of an explosive charge.
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Arbind, Archana. "Nonlinear Analysis of Conventional and Microstructure Dependent Functionally Graded Beams under Thermo-mechanical Loads." Thesis, 2012. http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11478.
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Nonlinear finite element models of functionally graded beams with power-law variation of material, accounting for the von-Karman geometric nonlinearity and temperature dependent material properties as well as microstructure dependent length scale have been developed using the Euler-Bernoulli as well as the first-order and third- order beam theories. To capture the size effect, a modified couple stress theory with one length scale parameter is used. Such theories play crucial role in predicting accurate deflections of micro- and nano-beam structures. A general third order beam theory for microstructure dependent beam has been developed for functionally graded beams for the first time using a modified couple stress theory with the von Karman nonlinear strain. Finite element models of the three beam theories have been developed. The thermo-mechanical coupling as well as the bending-stretching coupling play significant role in the deflection response. Numerical results are presented to show the effect of nonlinearity, power-law index, microstructural length scale, and boundary conditions on the bending response of beams under thermo-mechanical loads. In general, the effect of microstructural parameter is to stiffen the beam, while shear deformation has the effect of modeling more realistically as a flexible beam.