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Relevant bibliographies by topics / Eukaryotic gene; Genes; Chromosomal domain

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Academic literature on the topic 'Eukaryotic gene; Genes; Chromosomal domain'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Eukaryotic gene; Genes; Chromosomal domain"

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Nützmann, Hans-Wilhelm, Daniel Doerr, América Ramírez-Colmenero, et al. "Active and repressed biosynthetic gene clusters have spatially distinct chromosome states." Proceedings of the National Academy of Sciences 117, no. 24 (2020): 13800–13809. http://dx.doi.org/10.1073/pnas.1920474117.

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While colocalization within a bacterial operon enables coexpression of the constituent genes, the mechanistic logic of clustering of nonhomologous monocistronic genes in eukaryotes is not immediately obvious. Biosynthetic gene clusters that encode pathways for specialized metabolites are an exception to the classical eukaryote rule of random gene location and provide paradigmatic exemplars with which to understand eukaryotic cluster dynamics and regulation. Here, using 3C, Hi-C, and Capture Hi-C (CHi-C) organ-specific chromosome conformation capture techniques along with high-resolution micros

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Shopland, Lindsay S., Carol V. Johnson, Meg Byron, John McNeil, and Jeanne B. Lawrence. "Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains." Journal of Cell Biology 162, no. 6 (2003): 981–90. http://dx.doi.org/10.1083/jcb.200303131.

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Typically, eukaryotic nuclei contain 10–30 prominent domains (referred to here as SC-35 domains) that are concentrated in mRNA metabolic factors. Here, we show that multiple specific genes cluster around a common SC-35 domain, which contains multiple mRNAs. Nonsyntenic genes are capable of associating with a common domain, but domain “choice” appears random, even for two coordinately expressed genes. Active genes widely separated on different chromosome arms associate with the same domain frequently, assorting randomly into the 3–4 subregions of the chromosome periphery that contact a domain.

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LaSalle, Janine M., and Marc Lalande. "Domain organization of allele-specific DNA replication within the GABAA receptor gene cluster." Proceedings, annual meeting, Electron Microscopy Society of America 53 (August 13, 1995): 766–67. http://dx.doi.org/10.1017/s0424820100140208.

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Parental imprinting is a gamete-specific modification that distinguishes the paternal and maternal chromosomes in higher eukaryotes, resulting in allele-specific changes in chromatin organization, transcription and replication. One example of parental imprinting in humans is revealed by two distinct genetic diseases, Prader-Willi syndrome (PWS) and Angelman syndrome (AS) which both map to chromosome 15q11-13. PWS is caused by the absence of a paternal contribution to 15q11-13, while AS results from the lack of a maternal copy of the region. Within this chromosomal subregion lies a cluster of G

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Orlov, Y. L., O. Thierry, A. G. Bogomolov, et al. "Computer methods of analysis of chromosome contacts in the cell nucleus based on sequencing technology data." Biomeditsinskaya Khimiya 63, no. 5 (2017): 418–22. http://dx.doi.org/10.18097/pbmc20176305418.

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The study spatial chromosome structure and chromosome folding in the interphase cell nucleus is an important challenge of world science. Detection of eukaryotic genome regions that physically interact with each other could be done by modern sequencing technologies. A basic method of chromosome folding by total sequencing of contacting DNA fragments is HI-C. Long-range chromosomal interactions play an important role in gene transcription and regulation. The study of chromosome interactions, 3D (three-dimensional) genome structure and its effect on gene transcription allows revealing fundamental

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Schiklenk, Christoph, Boryana Petrova, Marc Kschonsak, et al. "Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1." Journal of Cell Biology 217, no. 7 (2018): 2383–401. http://dx.doi.org/10.1083/jcb.201711097.

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Although the formation of rod-shaped chromosomes is vital for the correct segregation of eukaryotic genomes during cell divisions, the molecular mechanisms that control the chromosome condensation process have remained largely unknown. Here, we identify the C2H2 zinc-finger transcription factor Zas1 as a key regulator of mitotic condensation dynamics in a quantitative live-cell microscopy screen of the fission yeast Schizosaccharomyces pombe. By binding to specific DNA target sequences in their promoter regions, Zas1 controls expression of the Cnd1 subunit of the condensin protein complex and

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Landis, G., and J. Tower. "The Drosophila chiffon gene is required for chorion gene amplification, and is related to the yeast Dbf4 regulator of DNA replication and cell cycle." Development 126, no. 19 (1999): 4281–93. http://dx.doi.org/10.1242/dev.126.19.4281.

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The Drosophila chorion genes encode the major protein components of the chorion (eggshell) and are arranged in two clusters in the genome. To meet the demand for rapid chorion synthesis, Drosophila ovary follicle cells amplify the chorion gene clusters approximately 80-fold. Amplification proceeds through repeated firing of one or more DNA replication origins located near the center of each gene cluster. Hypomorphic mutant alleles of the chiffon gene cause thin, fragile chorions and female sterility, and were found to eliminate chorion gene amplification. Null alleles of chiffon had the additi

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Kellum, R., and P. Schedl. "A group of scs elements function as domain boundaries in an enhancer-blocking assay." Molecular and Cellular Biology 12, no. 5 (1992): 2424–31. http://dx.doi.org/10.1128/mcb.12.5.2424.

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Chromosomes of higher eukaryotes are thought to be organized into a series of discrete and topologically independent higher-order domains. In addition to providing a mechanism for chromatin compaction, these higher-order domains are thought to define independent units of gene activity. Implicit in most models for the folding of the chromatin fiber are special nucleoprotein structures, the domain boundaries, which serve to delimit each higher-order chromosomal domain. We have used an "enhancer-blocking assay" to test putative domain boundaries for boundary function in vivo. This assay is based

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Kellum, R., and P. Schedl. "A group of scs elements function as domain boundaries in an enhancer-blocking assay." Molecular and Cellular Biology 12, no. 5 (1992): 2424–31. http://dx.doi.org/10.1128/mcb.12.5.2424-2431.1992.

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Chromosomes of higher eukaryotes are thought to be organized into a series of discrete and topologically independent higher-order domains. In addition to providing a mechanism for chromatin compaction, these higher-order domains are thought to define independent units of gene activity. Implicit in most models for the folding of the chromatin fiber are special nucleoprotein structures, the domain boundaries, which serve to delimit each higher-order chromosomal domain. We have used an "enhancer-blocking assay" to test putative domain boundaries for boundary function in vivo. This assay is based

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Shazadee, Hamna, Nadeem Khan, Jingjing Wang, et al. "Identification and Expression Profiling of Protein Phosphatases (PP2C) Gene Family in Gossypium hirsutum L." International Journal of Molecular Sciences 20, no. 6 (2019): 1395. http://dx.doi.org/10.3390/ijms20061395.

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The protein phosphatase (PP2C) gene family, known to participate in cellular processes, is one of the momentous and conserved plant-specific gene families that regulate signal transduction in eukaryotic organisms. Recently, PP2Cs were identified in Arabidopsis and various other crop species, but analysis of PP2C in cotton is yet to be reported. In the current research, we found 87 (Gossypium arboreum), 147 (Gossypium barbadense), 181 (Gossypium hirsutum), and 99 (Gossypium raimondii) PP2C-encoding genes in total from the cotton genome. Herein, we provide a comprehensive analysis of the PP2C ge

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Howe, Kerstin, Philipp H. Schiffer, Julia Zielinski, et al. "Structure and evolutionary history of a large family of NLR proteins in the zebrafish." Open Biology 6, no. 4 (2016): 160009. http://dx.doi.org/10.1098/rsob.160009.

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Multicellular eukaryotes have evolved a range of mechanisms for immune recognition. A widespread family involved in innate immunity are the NACHT-domain and leucine-rich-repeat-containing (NLR) proteins. Mammals have small numbers of NLR proteins, whereas in some species, mostly those without adaptive immune systems, NLRs have expanded into very large families. We describe a family of nearly 400 NLR proteins encoded in the zebrafish genome. The proteins share a defining overall structure, which arose in fishes after a fusion of the core NLR domains with a B30.2 domain, but can be subdivided in

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Dissertations / Theses on the topic "Eukaryotic gene; Genes; Chromosomal domain"

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Tufarelli, Cristina. "Activation and silencing of Î± globin expression." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365741.

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Book chapters on the topic "Eukaryotic gene; Genes; Chromosomal domain"

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Wasylyk, B. "Promoter Elements of Eukaryotic Protein-Coding Genes." In Chromosomal Proteins and Gene Expression. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-7615-6_7.

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Conference papers on the topic "Eukaryotic gene; Genes; Chromosomal domain"

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Pannekok, H., A. J. Van Zonneveid, C. J. M. de vries, M. E. MacDonald, H. Veerman, and F. Blasi. "FUNCTIONAL PROPERTIES OF DELETION-MUTANTS OF TISSUE-TYPE PLASMINOGEN ACTIVATOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643724.

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Over the past twenty-five years, genetic methods have generated a wealth of information on the regulation and the structure-function relationship of bacterial genes.These methods are based on the introduction of random mutations in a gene to alter its function. Subsequently, genetic techniques cure applied to localize the mutation, while the nature of the impairedfunction could be determined using biochemical methods. Classic examples of this approach is now considered to be the elucidation of the structure and function of genes, constituting the Escherichia coli lactose (lac) and tryptophan (

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