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Journal articles on the topic 'Ethnomedicinal herb'

Author: Grafiati
Published: 18 May 2024

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1

Zhu, Yun, Lulu Zhao, Xiangfei Wang, and Peng Li. "Pharmacognostical and phytochemical studies of Viola tianschanica Maxim. – An Uyghur ethnomedicinal plant." Journal of Pharmacy & Pharmacognosy Research 4, no. 1 (January 1, 2016): 95–106. http://dx.doi.org/10.56499/jppres16.105_4.3.95.

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Context: Viola tianschanica Maxim. (Violaceae) is a perennial herb widely distributed in Central Asia, especially in the Xinjiang of China. The whole herb has been used in traditional Uygur medicines as an antifebrile-detoxicate drugs. Aims: To characterize macroscopical and microscopical features of the root, leave and rhizome of the V. tianschanica Maxim. Explore and establish the micro-morphology and quality control methods for this plant. Methods: Pharmacognostic and phytochemical investigations were conducted regarding macroscopic, microscopic and preliminary phytochemical parameters. Results: It can be identified by structural features of flowers, structural characteristics of rhizome and root, specific thickening of endothecium cells of clinandrium can be regarded as identification character. This crude drug showed the characteristic physicochemical values like total ash (12%), water soluble ash (4.0%), acid insoluble ash (3.8%) and moisture content (6.5%). The ethanolic extract mainly contained flavonoids in this herb, also contained alkaloids, tannins, saponins, coumarin and absence of fats and protein. Conclusions: Various pharmacognostic and preliminary phytochemical characters observed in this test may help in standardization, identification and carrying out further research in V. tianschanica Maxim. based drugs used in Uygur traditional medicine and folk medicines. Sediment type of impurity content is higher in herbs; it should be paying attention to control quality of medicinal materials or drugs.
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Henri, Henri, Dayu Puspita Sari, and Luchman Hakim. "Medicinal Plants for Traditional Treatment Used by the Malays in South Bangka Regency, Indonesia." Biosaintifika: Journal of Biology & Biology Education 14, no. 1 (April 13, 2022): 125–34. http://dx.doi.org/10.15294/biosaintifika.v14i1.34455.

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The people of South Bangka Regency have been well-known for using plants as traditional medicine and applied it in their daily life, but the information about the indigenous medical system the limited written of documentation. This study aimed to describe the types of medicinal herbs, analyze the medicinal herbs used as traditional medicine, and discover the conservational effort practiced by the Malays which is the local ethnic of South Bangka Regency. The study employed a quantitative method with field observation techniques, interviews, and herbs identification. The data were analyzed using the ethnomedicinal quantitative method. The results showed that there were 117 species of medicinal herbs with 57 families, while the most frequently used herb was Areca catechu with the results of UV (0.16), FL (16.22), and RFC (0.004). On the important family value (FIV), the most frequently used herb was the Myrtaceae family with 9 species, followed by Poaceae with 8 species. One of the conservation efforts of medicinal plants is by conducting cultivation to help prevent extinction in their natural habitat.
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Aditya V. Ubhale, Pankaj H. Chaudhary, and Dipti B. Ruikar. "A comprehensive review on Lepidagathias crisata Wild." Journal of Ayurveda and Integrated Medical Sciences 9, no. 2 (April 10, 2024): 221–31. http://dx.doi.org/10.21760/jaims.9.2.34.

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The herb Lepidagathis cristata Willd. (Acanthaceae) is abundant in desert wastelands. The leaves, roots, flowers, seeds, and entire plant are all medicinally beneficial. The plant possesses a large number of phytochemicals that contributes to its different pharmacological activities. Fever, eczema, psoriasis, epilepsy, skin abscess, burns, mouth ulcer, snake bites, wounds, skin itching, and other skin problems are treated with this plant. As a result, the current study aims to shed light on the ethnomedicinal applications, phytoconstituents, pharmacological activity, and pharmaceutical preparations of the medicinal herb Lepidagathis cristata Willd, which belongs to the Acanthaceae family.
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A.Patel, Mital, Bhupesh Patel, and Preeti Pandya. "A Review On Ethnomedicinal Claims Of Acanthospermum Hispidum DC." International Research Journal of Ayurveda & Yoga 05, no. 06 (2022): 112–18. http://dx.doi.org/10.47223/irjay.2022.5617.

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Introduction:Plants are of immense value to human health and roughly 80% of world’s population relies on them for cure of various diseased conditions. The aim of present review was to provide the all available ethnomedicinal information and research updates pertainingtoAcanthospermum hispidum DC. Materials and Methods: Information regarding ethnomedicinal claim were reviewed by using the available books with especial reference to medicinal plants compiled from books on ethnobotany and research articles available on internet till date. The obtained Information were categorized as per vernacular names, locality, used parts, therapeutic claims, type and mode of administration along with ingredients and dosage forms of the preparations. Results: Acanthospermum hispidum DC. is annual herb in the family Asteraceae, which is native to central and south America, reported in 60 countries and moist habitat throughout India. This plant used as traditional medicine for various disease condition. All parts of plants are used for medicinal purpose through both the routes i.e external and internal. Conclusion: Acanthospermum hispidum DC. conducting provable scientific studies (pharmacological and clinical) were neededto establish its multiple ethnomedicinal claims.
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Eng-Chong, Tan, Lee Yean-Kee, Chee Chin-Fei, Heh Choon-Han, Wong Sher-Ming, Christina Thio Li-Ping, Foo Gen-Teck, et al. "Boesenbergia rotunda: From Ethnomedicine to Drug Discovery." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–25. http://dx.doi.org/10.1155/2012/473637.

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Boesenbergia rotundais a herb from theBoesenbergiagenera under the Zingiberaceae family.B. rotundais widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientists worldwide to further investigate its medicinal properties. Advancement in drug design and discovery research has led to the development of synthetic drugs fromB. rotundametabolites via bioinformatics and medicinal chemistry studies. Furthermore, with the advent of genomics, transcriptomics, proteomics, and metabolomics, new insights on the biosynthetic pathways ofB. rotundametabolites can be elucidated, enabling researchers to predict the potential bioactive compounds responsible for the medicinal properties of the plant. The vast biological activities exhibited by the compounds obtained fromB. rotundawarrant further investigation through studies such as drug discovery, polypharmacology, and drug delivery using nanotechnology.
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Saha, Jayati, and Prabir Kumar Sarkar. "In vitro antibacterial activity as related to antioxidant property of some ethnomedicinal plants." NBU Journal of Plant Sciences 9, no. 1 (2015): 40–45. http://dx.doi.org/10.55734/nbujps.2015.v09i01.005.

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The present study attempted to evaluate in vitro antibacterial and antioxidant activities of extracts from some ethnomedicinal herbs and to correlate among the parameters. The antibacterial activity was assayed using agar-disc diffusion method against seven bacterial species. Their total flavonoids content (TFC) and ferric reducing power (RP) were also evaluated. Herb extracts with high TFC exhibited a good antibacterial activity against the bacteria at low concentrations. The Gram-positive bacteria were more sensitive to the tested extracts than the Gram-negative ones. While Staphylococcus aureus was maximally inhibited, Escherichia coli was most resistant. Against each bacterium, antibacterial activity was positively correlated (r = 0.60-0.87) with TFC of the tested extracts. Positive correlations were also obtained between antibacterial and antioxidant activities (r = 0.60-0.96) as well as between TFC and antioxidant activity (r = 0.91) of the extracts. Thus, antibacterial and antioxidant activities of the tested extracts were closely associated with their flavonoid constituents.
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7

Jadhav, Dinesh. "Zea mays L. (Poaceae) – An Ethnomedicinal Plant Used in the Treatment of Kidney Stone by Native Folklore of Ratlam District (Madhya Pradesh)." Journal of Non Timber Forest Products 23, no. 4 (December 1, 2016): 233–34. http://dx.doi.org/10.54207/bsmps2000-2016-t171ap.

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Corn silk (Stigma maydis) is an important herb used traditionally by the native Indians to treat many diseases. It is also used as traditional medicine in many parts of the world such as China, Turkey, United States and France. In present study it has been found to be very effective for the treatment of kidney stone. This valuable ethnomedicinal plant is interestingly used by the inhabitants of Ratlam district (M.P.) to cure their kidney stone.
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Singh, Rajeev, and Arti Garg. "Parthenium hysterophorus L. - neither noxious nor an obnoxious weed." Journal of Non-Timber Forest Products 21, no. 4 (December 1, 2014): 223–25. http://dx.doi.org/10.54207/bsmps2000-2014-xnh377.

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The useful properties of Parthenium hysterophorus L. in terms of its multifarious utility in medicinal, pharmaceutical, pharmacognostic, cosmetic and agricultural sectors are elucidated and the species is established as a medicinal herb with enormous potential in drug designing for diabetes mellitus and cancer, as well as with wide scale applications in cosmetic and nanotechnology-based industries. One more ethnomedicinal use of this plant in joints pain is reported from some districts of Bihar and Uttar pradesh.
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Gemechu, Worku, Samuel Woldekidan, Firehiwot Teka, Jemal Mohammed, Rekik Ashebir, Bihonegn Sisay, Abiy Abebe, and Asfaw Meresa. "Ethnomedicinal uses, phytochemisty and pharmacological activities of Rumex nervosus." Journal of Analytical & Pharmaceutical Research 10, no. 2 (March 29, 2021): 65–69. http://dx.doi.org/10.15406/japlr.2021.10.00367.

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The genus Rumex is cosmopolitan plants consisted of about 200 species. Rumex nervosus that is known as nutraceutical plants widely distributed around the world. This review documents fragmented information on the ethnomedicial uses, phytochemistry and pharmacological activities of R. nervosus. The review articles are carried out by searching in PubMed, Google scholar and Google search up to December 2020. R. vernosus is traditionally used to treat eye disease, headache, teaniacapitis, haemorrhoids, dysentery, stomach-ache, diarrhoea, pharyngitis, arthritis, eczema, abscess and gynecological disorders. Secondary metabolites such as anthraquinones, naphthalenes, flavonoids, stilbenoids, triterpenes, carotenoids, and phenolic acids have been identified for this herb. The extracts of R. nervosus exhibited a wide range of pharmacological effects including antimicrobial, anti -inflammatory, antihypertensive, antidiabetic, antidiarrheal, anticoccidial and antileishimanial activities. These pharmacological studies have established a scientific basis for therapeutic uses of R. nervosus.
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Zhu, Yun, Yuan Xiong, Hehua Wang, and Peng Li. "Pharmacognostical and phytochemical studies on Ziziphora clinopodioides Lam. – A Kazakh and Uygur ethnomedicinal plant." Journal of Pharmacy & Pharmacognosy Research 5, no. 1 (January 1, 2017): 354–64. http://dx.doi.org/10.56499/jppres17.208_5.6.354.

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Context: Ziziphora clinopodioides Lam. (Lamiaceae) is an annual or perennial herb or subshrub widely distributed from the Mediterranean to central Asia and Afghanistan. In Xinjiang, China, the whole herb has been used in traditional Kazakh and Uygur medicines as anti-febrile and detoxicating drug. Aims: To characterize macroscopical, microscopically of the overground part of the Z. clinopodioides, explore and establish the macro-morphology, micro-morphology, quality and physicochemical parameters standards for this plant. Methods: Pharmacognostical and phytochemical investigations were conducted in terms of macroscopic, microscopic and preliminary phytochemical parameters. Results: The vegetable material can be identified by structural features of the flowers, structural characteristics of the stem, specific pale brown hesperidin can be regarded as identification character. This crude drug showed the characteristic physicochemical values like total ash (7%), insoluble ash (1.3%), water soluble ash (3.7%), moisture (7.5%). The ethanolic extract contained flavonoids, organic acids, alkaloids, and glycosides. Conclusions: Various pharmacognostical characters that observed in this study can be an effective supplement to further research of this ethnomedicinal plant. Meanwhile, the results of this paper deal with pharmacognostical studies on the Ziziphora clinopodioides in an attempt to mitigate the adulteration to the crude drug.
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E, Sowmiya, Rahul D, Rekka Raja, and Nirubama Kumar. "Ethnomedicinal plants used by the paniya tribes in Gurusimalai hills, Pandalur, Niligiri district." Kongunadu Research Journal 10, no. 1 (June 30, 2023): 28–39. http://dx.doi.org/10.26524/krj.2023.5.

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In the present report an attempt has been made to document the available ethno-medicinal plants and their application among Paniya tribes in Gurusimalai Hills, Pandalur, Niligiri district. Regular field trips were conducted during the months of July-November 2022. The information about the plants was recorded by means of discussion using standard questionnaire with the informers along with the field visits during the collection hours. According to the report of study, a total about 70 plant species belonging to 62 genera and 35 families for treating various kinds of ailments such as Fever, bronchitis, piles, ulcer, abdominal disorders, skin diseases, urinary discharges, snake bite, asthma, diabetes, heart diseases and weight loss. Among the parts, Root, leaves, fruits and Seeds were mainly utilized by the informants. A detailed analysis concluded that, Leaves (46 species) were the most frequently used part of a plant followed by the Fruit (15 species), Root (10 species), Seed (9 species), Whole plant parts, Flower and Bark (each 4 species), Stem (2 species) and Tuber (1 species). The most commonly used medicinal plants fell under shrub forms (25 species) followed by Herb (19 species), tree (13 species), Climber (12 species) and succulent herb (1 species). The mode of formulation preparation or administration was observed to be in the form of juice (27 species) followed by past (15 species), decoction (14 species), Powder (11 species), and vapour (3 species). The present study concluded that the native people in the study area have their unique way of utilizing medicinal plants to treat different kinds of ailments. This might pave the path for developing a scientifically validated botanical or lead to semi-synthetic derivatives intended for modern medicine.
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Aryal, Puspa, Mitra Lal Pathak, Gopal Sharma, and Damodar Dahal. "Ethnomedicinal Uses of Plants from Kapurkot, Salyan District, Nepal." Journal of Plant Resources 20, no. 1 (December 31, 2022): 150–58. http://dx.doi.org/10.3126/bdpr.v20i1.56605.

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The present study aims to document the traditional knowledge of medicinal plants of Kapurkot rural municipality of Salyan District, Karnali province, Nepal. Ethno medicinal information was collected through interview with 40 respondents from Mulpani, Sallyan District. Altogether 59 ethnomedicinal plant species are used for the remedies of different health ailments. Respondents of the age group 25-35 years were found actively participating in this survey. Zingiberaceae as well as the Lauraceae family were found to have the highest number of species used for ethno-medicinal purposes. On the basis of their habit, herb species are found to be highly dominated. The recorded 59 ethnomedicinal plants were used in the treatment of various diseases such as cuts and wounds, skin diseases, fever, cough, boils, burns, common cold, etc. From this study, mainly common cold and cough are mostly recovered ailments from medicinal plant species. The study is mainly based on the experienced knowledge and information which they gain from their elders, mainly from grandparents, which might pass from generation to generation. This current study reveals that Zanthoxylum armatum (Timur), Cinnamomum tamala (Tejpaat) and Zingiber officinale (Adhuwa) are respectively found to be highly traded medicinal plants of the study area. For the preservation of ethnomedicinal plants species as well as their traditional knowledge, different conservation activities should be practiced. Such gained information and knowledge should be passed from generation to generation and encourage them to preserve for sustainable use of traditional documentation.
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Sharma, Vineet, Rohit Sharma, DevNath Singh Gautam, Kamil Kuca, Eugenie Nepovimova, and Natália Martins. "Role of Vacha (Acorus calamus Linn.) in Neurological and Metabolic Disorders: Evidence from Ethnopharmacology, Phytochemistry, Pharmacology and Clinical Study." Journal of Clinical Medicine 9, no. 4 (April 19, 2020): 1176. http://dx.doi.org/10.3390/jcm9041176.

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Vacha (Acorus calamus Linn. (Acoraceae)) is a traditional Indian medicinal herb, which is practiced to treat a wide range of health ailments, including neurological, gastrointestinal, respiratory, metabolic, kidney, and liver disorders. The purpose of this paper is to provide a comprehensive up-to-date report on its ethnomedicinal use, phytochemistry, and pharmacotherapeutic potential, while identifying potential areas for further research. To date, 145 constituents have been isolated from this herb and identified, including phenylpropanoids, sesquiterpenoids, and monoterpenes. Compelling evidence is suggestive of the biopotential of its various extracts and active constituents in several metabolic and neurological disorders, such as anticonvulsant, antidepressant, antihypertensive, anti-inflammatory, immunomodulatory, neuroprotective, cardioprotective, and anti-obesity effects. The present extensive literature survey is expected to provide insights into the involvement of several signaling pathways and oxidative mechanisms that can mitigate oxidative stress, and other indirect mechanisms modulated by active biomolecules of A. calamus to improve neurological and metabolic disorders.
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Roy, Shibanjan Paul, Ragini Bundela, Sourabh Jain, and Karunakar Shukla. "Role of Vacha as Neurological and Metabolic Disorders: Evidence from Ethnopharmacology, Phytochemistry, Pharmacology and Preclinical Study." Journal of Drug Delivery and Therapeutics 12, no. 6-S (December 26, 2022): 106–13. http://dx.doi.org/10.22270/jddt.v12i6-s.5713.

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Vacha (Acorus calamus Linn (Acoraceae)) is a traditional Indian medicinal herb, which is practiced to treat a wide range of health ailments, including neurological, gastrointestinal, respiratory, metabolic, kidney, and liver disorders. The purpose of this paper is to provide a comprehensive up-to-date report on its ethnomedicinal use, phytochemistry, and pharmacotherapeutic potential, while identifying potential areas for further research. To date, 145 constituents have been isolated from this herb and identified, including phenylpropanoids, sesquiterpenoids, and monoterpenes. Compelling evidence is suggestive of the biopotential of its various extracts and active constituents in several metabolic and neurological disorders, such as anticonvulsant, antidepressant, antihypertensive, anti-inflammatory, immunomodulatory, neuroprotective, cardioprotective, and anti-obesity effects. The present extensive study is expected to provide insights into the involvement of several signaling pathways and oxidative mechanisms that can mitigate oxidative stress, and other indirect mechanisms modulated by active biomolecules of A. calamus to improve neurological and metabolic disorders. Keywords: Acorus calamus, Acoraceae, Phytochemistry, Pharmacotherapeutic potential
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15

Yob, N. J., S. Mohd Jofrry, M. M. R. Meor Mohd Affandi, L. K. Teh, M. Z. Salleh, and Z. A. Zakaria. "Zingiber zerumbet(L.) Smith: A Review of Its Ethnomedicinal, Chemical, and Pharmacological Uses." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–12. http://dx.doi.org/10.1155/2011/543216.

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Zingiber zerumbetSm., locally known to the Malay as “Lempoyang,” is a perennial herb found in many tropical countries, including Malaysia. The rhizomes ofZ. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory- and pain-mediated diseases, worm infestation and diarrhea). Research carried out using differentin vitroandin vivoassays of biological evaluation support most of these claims. The active pharmacological component ofZ. zerumbetrhizomes most widely studied is zerumbone. This paper presents the botany, traditional uses, chemistry, and pharmacology of this medicinal plant.
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Kosai, Piya, Kanjana Sirisidthi, Kanitta Jiraungkoorskul, and Wannee Jiraungkoorskul. "Review on Ethnomedicinal uses of Memory Boosting Herb, Butterfly Pea, Clitoria ternatea." Journal of Natural Remedies 15, no. 2 (December 5, 2015): 71. http://dx.doi.org/10.18311/jnr/2015/480.

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<em>Clitoria ternatea</em> (Family: Fabaceae) is one of the traditional medicinal plants used as “Shanka Pushpi” an Ayurvedic medicine used to boost or enhance neurological health. The plant contains alkaloid, flavonoid, taraxerol, taraxerone, triterpenoid and anthocyanin as active chemicals that bring about its biological effects. Its extracts possess a wide range of pharmacological activities including antibacterial, anti-diabetic, anti-diarrheal, anti-fungal, anti-helmintic, anti-inflammatory, antimicrobial, antioxidant, and antipyretic activities, hypolipidemia, immunomodulatory, and wound healing. This review is an attempt to compile information on various ethno medicinal uses of memory boosting herb, butterfly pea, <em>Clitoria ternatea</em>. <strong>Conclusion</strong>: It has a wide spectrum of neuro pharmacological benefits such as nootropic, anti-depressant, anti-stress, anxiolytic, and anticonvulsant activities.
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Premkumar, G., R. Sankaranarayanan, S. Jeeva, and K. Rajarathinam. "Cytokinin induced shoot regeneration and flowering of Scoparia dulcis L. (Scrophulariaceae)–an ethnomedicinal herb." Asian Pacific Journal of Tropical Biomedicine 1, no. 3 (June 2011): 169–72. http://dx.doi.org/10.1016/s2221-1691(11)60020-8.

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18

Naik, Swasha Khandeparker, B. L. Manjula, M. Vaidagi Balaji, Sugimani Marndi, Sanjeet Kumar, and Rajkumari Supriya Devi. "Antibacterial Activity of Justicia betonica Linn." Asian Pacific Journal of Health Sciences 9, no. 4 (June 20, 2022): 227–30. http://dx.doi.org/10.21276/apjhs.2022.9.4.45.

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Justicia betonica L., (Acanthaceae) is widely used as a traditional folk medicinal herb. Conventionally, the plant is used to cure constipation, diarrhea, malaria, pain, stomach ache, vomiting, etc. The plant possesses many therapeutic uses such as analgesic, anti-inflammatory, antimalarial, and antimicrobial properties. The present work has been designed to document the ethnomedicinal properties, phytochemistry, and antibacterial activity of J. betonica. Phytochemical results showed that the presence of wide variety of biologically active compounds such as flavonoids, alkaloids, tannins, and phenolic compounds. Antibacterial activity showed that the inhibition was observed with the individual extracts and was effective against all bacterial strains tested. The present study highlights the importance of J. betonica.
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19

Patel, Sapan, R. K. Tenguria, and P. K. Mishra. "Pharmacological and ethnomedicinal studies of Tridax procumbens linn family (Compositeae) for anti-asthmatic activities." Environment Conservation Journal 6, no. 1-3 (December 19, 2005): 27–31. http://dx.doi.org/10.36953/ecj.2005.0612304.

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Tridax procumbens linn. of family- Compositeae (Asteraceae) is found plentifully in the plane areas near rivers and on marshy land. The villagers use this plant in bronchial asthma, dysentery and diarrhaea. Leaf juice is generally used to kill the bed bug in cote and wooden furniture and to protect the woods from termites etc.The whole herb juice in decoction is used by the villagers to check the hemorrhage of wounds.The detailed chemistry of the insecticidal compound was carried out, which revealed the structure of the compound. In the present communication, an effort has been made to screen the Tridax procumbens,a common plant used in folk medicines.
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Banerjee, Rahul, Sudeepa Ghosh, and Avik Acharya Chowdhury. "REVIEW ON MULTIFACETED ANTICANCER ACTIVITY OF OCIMUM SANCTUM AND ITS CONSTITUENTS: PAST, PRESENT AND FUTURE." Suranaree Journal of Science and Technology 30, no. 2 (May 29, 2023): 030101(1–9). http://dx.doi.org/10.55766/sujst-2023-02-e02062.

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Ocimum sanctum Linn (OS), is the medicinal herb belonging to the Lamiaceae family, well-known as the ‘Holi Basil’ or ‘Tulsi”. It has been a part of ayurveda and Indian culture for its tremendous ethnomedicinal significance as it is employed to cure common cough and cold along with bronchitis, skin diseases, insect bite etc. The leaves of OS in particular are widely used for the treatment of cancer. Approximately 15 different types of biologically active chemicals have been extracted, purified and identified from this medicinal herb. The anticancer properties of the crude and purified products from OS have been studied extensively over decades. They showed tumor suppressive, radioprotective, chemo-preventive, anti-metastatic, anti-angiogenic and apoptotic effect on various types of cancer. This review summarizes the anticancer effect and mechanism of the purified products and extract obtained from OS on various cancers like breast, colon, lung, liver etc. The summarized report would help to fine-tune our understanding on the anti-cancer properties of OS that might open up new horizon in developing natural product-based cost- efficient cancer drug.
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Misra, Debabrata, Manab Mandal, Narendra Nath Ghosh, and Vivekananda Mandal. "Pharmacognostic Standardization of an Ethnomedicinal Aquatic Herb, Monochoria hastata (L.) Solms for its Antibacterial Potentiality." Pharmacognosy Journal 10, no. 3 (May 10, 2018): 533–40. http://dx.doi.org/10.5530/pj.2018.3.87.

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Murkar, Sayali, Nishigandha Jadhav, Snehal Veer, and Pravin Badhe. "Ocimum Sanctum Linn. (Tulsi): An Ethnomedicinal Herb Used in the Prevention and Treatment of Cancer." International Journal of Pharmaceutical Sciences and Medicine 8, no. 6 (June 30, 2023): 1–12. http://dx.doi.org/10.47760/ijpsm.2023.v08i06.001.

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For thousands of years prior to the development of western medicine, people used traditional medicine to cure various ailments. With cancer being the most serious hazard to humanity, ethnomedicine can play an important role in cancer prevention and treatment. Among all therapeutic herbs, Ocimum sanctum Linn has chemo-preventive molecules and chemicals with anti-carcinogenic activity. In Ayurvedic medicine, its leaves, seeds, and roots are used. Numerous nutrients and bioactive substances may be found in Tulsi. The main chemical components of Tulsi include rosmalinic acid, oleanolic acid, caryophyllyne, and linalool. Some of its phytochemicals, such as eugenol, rosmarinic acid, apigenin, myretenal, luteolin, -sitosterol, and carnosic acid, have also been shown to prevent chemically induced skin, liver, oral, and lung cancers. These effects are mediated by increasing antioxidant activity, altering gene expression, inducing apoptosis, and inhibiting angiogenesis and metastasis. Studies on Ocimum Sanctum's possible effectiveness against conditions like breast, skin, and lung cancer have been conducted. All of these sorts of cancer diseases may be treated with this as an additional or complementary medication, and it can be included in many ways into a regular diet.
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Oppong Bekoe, Emelia, Gladys Schwinger, Cindy Kitcher, and Alexander Nyarko. "The Use of <i>Ocimum gratissimum</i> L. in the Treatment of Gastrointestinal Ailments." Journal of Natural Remedies 21, no. 4 (October 1, 2021): 275. http://dx.doi.org/10.18311/jnr/2021/26507.

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Diseases that affect the digestive tract are referred to as Gastrointestinal ailments. Gastrointestinal (GI) ailments contribute substantially to healthcare costs all over the world. <em>Ocimum gratissimum</em>, commonly known as African basil is a wellknown medicinal herb with a wide therapeutic potential. In most West African homes, it is employed as a home remedy for treating GI ailments such as diarrhoea, colitis, stomach ulcers, bloating, among several other conditions. Anecdotal reports support its efficacy in the treatment of these disease conditions. This review summarizes ethnomedicinal data for the use of <em>O. gratissimum</em> in the management of gastrointestinal ailments, and its potential clinical application based on its pharmacological activity.
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Mukim, Mohammad, Atul Kabra, Christophe Hano, Samantha Drouet, Duangjai Tungmunnithum, Mohit Chaturvedi, Rakesh Patel, Muhammad Ayaz, and Daniel M. Shadrack. "Rivea hypocrateriformis (Desr.) Choisy: An Overview of Its Ethnomedicinal Uses, Phytochemistry, and Biological Activities and Prospective Research Directions." Journal of Chemistry 2022 (June 22, 2022): 1–11. http://dx.doi.org/10.1155/2022/9099672.

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Rivea hypocrateriformis (Desr.) Choisy is a robust woody climbing shrub of the genus Rivea which is widely distributed in India, Nepal, Sri Lanka, Pakistan, Bangladesh, Myanmar, and Thailand. R. hypocrateriformis is a promising medicinal herb with a wide range of beneficial and health-promoting properties. Since the ancient times, it has been used as a traditional medicine to treat rheumatic pain, fever, urogenital problems, snake bites, cough, piles, malaria, and skin diseases. Aside from these traditional uses, its leaves and young shoots are also cooked and eaten as a vegetable and used for the preparation of bread with millet flour. This study extensively analyzes the available information on R. hypocrateriformis botanical characterization, distribution, traditional applications, phytochemistry, pharmacology, and toxicological properties. Phytochemical investigations of the plant has revealed the presence of highly valuable secondary metabolites including alkaloids, glycosides, coumarins, flavonoids, xanthones, stilbenes, and other organic compounds. Its crude extracts and isolated compounds have revealed anovulatory, antifertility, antiarthritic, antimicrobial, anticancer, antioxidant hepatoprotective, antilithiatic, and antimitotic potentials. This review of literature clearly identifies R. hypocrateriformis as a potent medicinal plant with remarkable healing and health-promoting properties. Further research directions into the bioactive extracts, clinical, and toxicological evaluations to assess the beneficial health-promoting properties of this promising herb are also discussed.
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Maqsood, Tasneem, Tayyaba Munawar, Yamin Bibi, Ahmad El Askary, Amal F. Gharib, Tariq E. Elmissbah, Basem H. Elesawy, and Abdul Qayyum. "Study of plant resources with ethnomedicinal relevance from district Bagh, Azad Jammu and Kashmir, Pakistan." Open Chemistry 20, no. 1 (January 1, 2022): 146–62. http://dx.doi.org/10.1515/chem-2022-0129.

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Abstract An ethnomedicinal expedition was conducted to collect and record indigenous knowledge about the use of medicinal plants by local inhabitants of four villages (Chittra, Topi, Pandi, and Kalri) of district Bagh, Azad Jammu and Kashmir. Ethnomedicinal data were obtained from 60 randomly selected local inhabitants of the study area through semi-structured questionnaires and interviews. These data were analyzed quantitatively through different ethnobotanical indices including family importance value, relative frequency of citation, use value (UV), fidelity level (FL), informant consensus factor (ICF), and Jaccard index (JI). our study reported 69 medicinal plants belonging to 39 families. Rosaceae (9 species) was a dominant family of the study area. Herb (54.83%) was dominant growth form of plants used for medicinal purpose. Leaves contributed maximum usage (44.29%) for curing diseases. Decoction (23 records) was most used mode of utilization. Relative frequency of citation and UV ranged from 0.03–0.85 and 0.05–1.17, respectively. There were 4 plant species with 100% FL. Highest ICF (0.88%) was found for gastrointestinal diseases. By comparing results with previous study, JI ranged from 0.54 to 24.43%. Our results found that there were 18 plant species not reported with ethnomedicinal aspect in previous studies from district Bagh region. The research of this study concludes that the area is rich with medicinal plants and the local inhabitant of this area still prefer medicinal plants over allopathic medicines for treating different ailments. Comparative analysis has shown some novel uses of plant species which may be due to cultural differences of the study area. However, awareness and pharmacological study are needed to conserve and unveil pharmaceutically important plants.
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Rai, Sangen Ruma. "Phytochemical Screening of Ethnomedicinal Herbal Extracts and their Effect on Microbial Quality of Sukuti." Himalayan Journal of Science and Technology 6, no. 1 (December 31, 2022): 87–95. http://dx.doi.org/10.3126/hijost.v6i1.50599.

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The effect of herbal extracts of four ethnomedicinal herbs (Zanthoxylumarmatum, Litsea cubeba, Heracleum nepalense, and Evodia fraxinifolia) of culinary importance on the microbial quality of sukuti (a traditional dried meat product) was studied. Herbal extracts were prepared by grinding each herb to particle size < 250 μm, extracting in 50% (v/v) ethanol, and concentrating in a rotary vacuum evaporator at 50oC. Four of the spoilage and pathogenic microorganisms, viz., Salmonella, Staphylococcus, E. coli, and Lactobacillus were isolated from market sukuti samples and used as test organisms for the study. Herbal extracts at the concentration of 40, 20, 10, and 2 mg/ml were tested against the test organisms to determine the antimicrobial property of the extracts. The herbal extract showing the greatest antimicrobial activity was selected for use in optimized product (sukuti) development. The total phenolic content of the herbal extracts was also determined. The analyses were performed in triplicate. The data were checked for homogeneity before being analyzed with ANOVA in Genstat Release v12. The Fisher's Least Significant Difference (LSD) method was used to compare data means at a 5% level of significance. Zanthoxylum armatum at 40 mg/ml concentration showed the largest zone of inhibition (ZOI) against the test organisms and was therefore selected for final product development. Meat strips (1 cm × 1 cm × 25 cm) were marinated with Zanthoxylum armatum (40 mg/ml) extract at the rate of 2%, aged (24 h at 4 ± 2oC), and dried in a cabinet dryer for 2 days at 55oC. The total plate counts (TPCs) of control (untreated)- and herbal (treated) sukuti were carried out for 20 days at an interval of 10 days to determine the microbial stability of the final product. The TPC for the treated sample was significantly lower (p<0.05) than that of the untreated sample.
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Sasikala, Nambi, and R. Ramasubbu. "Population status and floral biology of Trichopus zeylanicus ssp. travancoricus Burkill ex K. Narayanan (Dioscoreaceae), an important ethnomedicinal plant of the southern Western Ghats, India." Journal of Threatened Taxa 11, no. 1 (January 26, 2019): 13156–61. http://dx.doi.org/10.11609/jott.3502.11.1.13156-13161.

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Trichopus zeylanicus ssp. travancoricus is locally known in Tamil Nadu as Arogyapachai, meaning a plant that provides good health and vitality. The unripe fruits of the plant are highly rejuvenating and are used by the Kani Tribe to ameliorate fatigue. This subspecies is also known for its pharmacological and medicinal utility and possesses choleretic, aphrodisiac, hepatoprotective, mast cell stabilizing, adaptogenic, and cardioprotective properties. A study was attempted to understand the population status and floral biology of T. zeylanicus ssp. travancoricus in its natural habitat. The population of this herb was found to be severely fragmented and settled in shaded banks of streams and rivulets in Agasthyamalai Hills. Being a rhizomatous herb, its flowers are concealed by its broad leaves, thus preventing exposure to pollinators. The number of pollinating agents in the flowers was reported as meager. The fruits are capsules with two to six seeds, each having a hard seed coat with a projected endosperm. Therefore, the conventional propagation of the subspecies is not so successful due to its poor seed set and prolonged maturation time. In addition, the fruits are damaged by rodents, livestock, and collection for medicinal usage, which severely affect the population status of the plant. Sustainable use of this wonder herb is important for its conservation in its natural habitat.
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Naik, Swasha Khandeparker, B. L. Manjula, M. Vaidagi Balaji, Sugimani Marndi, Sanjeet Kumar, and Rajkumari Supriya Devi. "Antibacterial Activity of Justicia betonica Linn." Asian Pacific Journal of Health Sciences 9, no. 4 (June 25, 2022): 87–90. http://dx.doi.org/10.21276/apjhs.2022.9.4s.16.

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Justicia betonica L. (Acanthaceae) is widely used as a traditional folk medicinal herb. Conventionally, the plant is used to cure constipation, diarrhea, malaria, pain, stomach ache, vomiting, etc. The plant possesses many therapeutic uses such as analgesic, anti-inflammatory, antimalarial, and antimicrobial properties. The present work has been designed to document the ethnomedicinal properties, phytochemistry, and antibacterial activity of J. betonica. Phytochemical results showed that the presence of wide variety of biologically active compounds such as flavonoids, alkaloids, tannins, and phenolic compounds might be responsible for therapeutic values of Justicia betonica. Antibacterial activity showed that the inhibition was observed with the individual extracts and was effective against all bacterial strains tested. The present study highlights the importance of J. betonica.
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Siraj, Mantasha Binth, Asim Ali Khan, and Umar Jahangir. "Therapeutic Potential of Evolvulus alsinoides." Journal of Drug Delivery and Therapeutics 9, no. 4-s (August 15, 2019): 696–701. http://dx.doi.org/10.22270/jddt.v9i4-s.3302.

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Background: Evolvulusalsinoidesis a well-known herbal drug possessing various promising medicinal properties described by prominent ancient scholars and also numerous preclinical and clinical researches has been performed, thus attestingit’s ample of pharmacological actions. So, thorough review of classical as well as contemporary literature has been executed on Evolvulusalsinoides to validate the pharmacological actions mentioned. . Methods:For classical review,a comprehensive search of Unani literature is done and for latest research work on evolvulus, articles published in English language using PubMed, MEDLINE, and the Google scholar with search term including Sahnkpushpi, sankhaoli, Evolvulusalsinoides since 1991 to 2019 is done. Results: The search includescontemporary literature, ethnomedicinal sources and 35 research articles from 1992 to 2019 which further ascertains various pharmacological actions being mentioned in Unani literature including anti-inflammatory, anti-diarrheal, anti-helminthic, anti-convulsantand nootropicproperty of herb. Conclusion: The pharmacological action and therapeutic application of Shankhaholi/ Shankpushpiwhich ismentioned inclassical Unani literature are in accordance with latest research. Despite of having several researches on Evolvulusalsinoides there are still numerous indications mentioned in classical literature which are yet to be explored. Keywords: Evolvulusalsinoides, herb, Unani, contemporary.
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Khan, Afshan, Aisha Siddiqui, Anwar Jamal, and Gulnar Fatima. "Lallemantia royleana Benth. (Balangu): A Compendious Review on Phytochemistry, Pharmacology and Ethnomedicinal Uses." Journal of Drug Delivery and Therapeutics 9, no. 5-s (October 18, 2019): 175–77. http://dx.doi.org/10.22270/jddt.v9i5-s.3279.

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Lallemantia royleana Benth. is an annual, biennial or perennial herb, belonging to the family Lamiaceae, commonly known as Balangu. It is cultivated throughout Western Asia, India, Pakistan and Northern of Iraq. In Unani system of medicine it act as a Mudire Baul (Diuretic), Muqawwi Qalb (Cardiotonic), Musakkin (Sedative) etc and used for treatment of Nazla wa Zukam (Common cold) , Humma (Fever), Dard Mafasil (Joint pain), Hudar (Rheumatism), Amraze Gurda (Renal disorder), Zofe Qalb (Weakness of heart) etc. Traditional observation reports that this plant retains potential to cure infectious diseases. Nowadays, it is receiving substantial consideration by scientist and pharmaceutical research industries with the aim to explore for more effective substitute. The seeds contain linoleic, oleic, betasitosterol, palmitic and stearic acids, its gums are composed of L-rhamnose, L-arabinose, D-galactose, protein, uronic anhydride and are generally used for the treatment of abscesses, inflammation and respiratory problems, also used in drinks due to its sedative effects. This plant seems to possess many undiscovered pharmacological properties which have to be explored. Keywords: Lallemantia royleana Benth, Unani medicine, Traditionl medicine.
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Saggoo, M. I. S., I. A. Nawchoo, and Arifa Akhter. "Meiotic Irregularities in Lavatera cachemiriana, an Endemic, Endangered and Ethnomedicinal Herb of Kashmir Himalaya." CYTOLOGIA 82, no. 3 (2017): 235–39. http://dx.doi.org/10.1508/cytologia.82.235.

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Sumitha, V., I. Mini, and Laija S. Nair. "Assessment of Hepatoprotective Activity of Hyptis capitata Jacq. Against Oxidative Stress Induced by H2O2." International Journal of Pharmaceutical Sciences and Drug Research 14, no. 01 (March 28, 2022): 43–47. http://dx.doi.org/10.25004/ijpsdr.2022.140106.

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Medicinal plants occupy a key position in maintaining the health of the human population. Hyptis capitataJacq. is an exotic ethnomedicinal plant of Lamiaceae possessing immense potential. The present study was carried out to assess the in vitro hepatoprotective activity of methanolic leaf extract of H. capitata against H2O2 induced oxidative stress in HepG2 cell lines. Total antioxidant capacity and Superoxide radical scavenging activity of the extract were also performed. The extract displayed considerable free radical scavenging activity (P IS LESS THAN 0.01). MTT assay was used to assess the in vitro hepatoprotective activity in HepG2 cell lines. The extract displayed concentration-dependent cell viability with maximum protection (63.97 ± 1.23%) in H2O2 induced HepG2 cell lines at 100 μgml-1. H. capitata is a promising herb with significant antioxidant and hepatoprotective potential.
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Balkrishna, Acharya, Shalini Singh, Deepika Srivastava, Shalini Mishra, Satyendra Kumar Rajput, and Vedpriya Arya. "Quassia amara L.: A Comprehensive Review of its Ethnomedicinal Uses, Phytochemistry, Pharmacology and Toxicity." Journal of Phytopharmacology 11, no. 3 (June 25, 2022): 194–99. http://dx.doi.org/10.31254/phyto.2022.11310.

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Quassia amara Linn., is a shrub and world widely known as ‘bitter-wood’ belongs to Simaroubaceae family. The plant grows in sandy soils of lowland & highland forests, wet forests along riverbanks and, is native to Central Mexico to Southern tropical America and Guadalupe. A Surinamese man named Quassia which gained attention for treating fevers with a secret remedy based on this herb in 18th century, which Rolande took to Sweden in 1756 and disseminated its medicinal reputation across Europe. This species consists of various constituents namely β-carbonite, indole alkaloids & primarily, the bitter compounds known as quassinoids. Various studies indicate that Q. amara possess different biological properties namely anti-diabetic, anti-inflammatory, anti-hyperglycemic, anti-leishmanial, antimalarial, anti-nociceptive, anti-ulcer, anti-fertility and sedative. Fresh bark, leaves or wood extracts are used to treat digestive problems, malaria and hepatic disorders. In-depth literature analysis revealed that the plant is least explored and possess immense medicinal values. These studies pass the new ways to explore biological potential of this plant.
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Deepa, A. V., and T. Dennis Thomas. "High-frequency direct shoot induction from leaf explants of Pogostemon quadrifolius (Benth.) F. Muell.: an ethnomedicinal herb." In Vitro Cellular & Developmental Biology - Plant 58, no. 2 (March 30, 2022): 321–29. http://dx.doi.org/10.1007/s11627-022-10265-w.

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Abraham, Jyothi, and T. Dennis Thomas. "Plant regeneration from organogenic callus and assessment of clonal fidelity in Elephantopus scaber Linn., an ethnomedicinal herb." Physiology and Molecular Biology of Plants 21, no. 2 (April 2015): 269–77. http://dx.doi.org/10.1007/s12298-015-0281-7.

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Cheruvathur, Meena K., and T. Dennis Thomas. "An efficient plant regeneration system through callus for Pseudarthria viscida (L.) Wright and Arn., a rare ethnomedicinal herb." Physiology and Molecular Biology of Plants 17, no. 4 (October 2011): 395–401. http://dx.doi.org/10.1007/s12298-011-0089-z.

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Sanusi, Idris Olatunji, Akolade Ridwan Oladipupo, and Stephenie Chinwe Ama Alaribe. "Evaluation of sub-acute oral toxicity effects of Phaulopsis falcisepala C.B. Clarke (Acanthaceae) in rats." Bio-Research 21, no. 1 (January 12, 2023): 1763–77. http://dx.doi.org/10.4314/br.v21i1.1.

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Phaulopsis falcisepala is a herb or undershrub found in forest zone of West Africa and used for a wide range of ethnomedicinal purposes. Despite the ethnomedicinal importance of P. falcisepala, detailed data about its safety and toxicity is lacking. This study was done to evaluate sub-acute toxicity of P. falcisepala in rats. Whole plant of P. falcisepala was extracted with methanol. Wistar rats (n = 6/group) were administered orally with P. falcisepala extract at doses of 250, 500 and 1000 mg/kg/day for 28 days. Control group received distilled water. Physical observations were recorded daily and weights of animals were recorded weekly. After 28 days, samples of blood, serum and vital organs were obtained for haematological, biochemical and histological evaluations. Results showed that daily oral doses of P. falcisepala extract up to 1000 mg/kg for 28-days did not cause any behavioral changes or mortality. The plant extract did not induce significant alterations in body-weights, haematological, hepatic and renal parameters and serum levels of sodium, potassium, and chloride ions. No significant differences (p > 0.05) were recorded in relative weights of ovaries, testes, heart and kidneys of experimental groups compared to control group. Changes were observed in lipid profile (p < 0.05) and histology of kidneys and liver of rats treated with plant extract, particularly at highest dose, 1000 mg/kg. These findings suggest that extract of P. falcisepala could be safely applied for its medicinal properties at low to medium doses. However, sub-acute administration of doses up to 1000 mg/kg/day could pose deleterious risk to liver and kidneys.
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Yu, Huang-he, Ye Lin, Rong Zeng, Xin Li, Ting Zhang, Shumaila Tasneem, Cong Chen, et al. "Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb." Journal of Ethnopharmacology 238 (June 2019): 111902. http://dx.doi.org/10.1016/j.jep.2019.111902.

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Bishnoi, Rameshwar Lal, Nandlal ., Samiksha ., Ashwini Kumar Sharma, and Sandeep . "A REVIEW ON SHAMI (PROSOPIS CINERARIA L.) AN ETHNOMEDICINAL PLANT IN A DESERT AREA OF RAJASTHAN, INDIA." International Journal of Research in Ayurveda and Pharmacy 14, no. 6 (December 31, 2023): 15–18. http://dx.doi.org/10.7897/2277-4343.1406159.

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Prosopis cineraria is a member of the Leguminosae family, often referred to as Khejri, Khijdo, Shami, and Jandi. The tree is known as Kalptaru because all of its components are beneficial. It is also known as the "wonder tree," making it the "lord of the desert." Locally known as "Sangari," the pods are fresh green vegetables that Rajasthani people enjoy together with its dry fruits. In times of scarcity, make pickles with Karir (Capparis decidua) and use them with bajara chapati as a meal. It is also a good source of vitamins for people who live in desert areas. The herb has also been employed as a folk treatment for various illnesses in indigenous folk medicine systems, including leprosy, dysentery, bronchitis, asthma, leukoderma, piles, muscle spasms, and wandering thoughts. Plant components such as leaves, pods, flowers, stems, and seeds have unique metabolites. Significant phytochemical substances found in plants have previously been identified as including fatty acids, carbohydrates, protein, saponins, tannins, alkaloids, and glucoside. Analgesic activity, antitumor activity, anticonvulsant activity, antihyperlipidemic activity, antipyretic activity, and antimicrobial activity are some of the pharmacological properties of plants.
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Ofuegbe, OS, and AA Adedapo. "Ethnomedicinal survey of some plants used for the treatment of diabetes in Ibadan, Nigeria." Asian Journal of Medical Sciences 6, no. 5 (March 8, 2015): 36–40. http://dx.doi.org/10.3126/ajms.v6i5.10480.

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Objectives: A comprehensive survey with the aim of documenting traditional medicinal practices was carried out in targeted areas of Ibadan, Nigeria in order to inventory plants used by traditional healers in the area for the management of diabetes. Materials and Methods: Open-ended informal interviews were administered during series of repeated visits to the respondents consisting majorly the traditional medical practitioners (TMPs) and herb sellers. Some traditional healers who know and use medicinal plants for treating diabetes mellitus were interviewed. The inventory contains scientifi c, vernacular, common names of the plants used and methods of preparation. Results: Twenty seven plants commonly used by traditional healers in the region were identifi ed. These plants were found to be very important and useful in the treatment of diabetes based on their frequency of occurrence in the recipes obtained. Herbal remedies were either prepared from dried or freshly collected plants while traditional solvent of choice included water, lime, local gin and aqueous extract from fermented maize. Decoction and pulverization were the main methods of preparation while mode of administration varies within 1 to 3 times daily. Survey revealed that leaves form the major part of plants for herbal preparations. Residents in the study area fi nd traditional medicine cheaper as compared to orthodox medicine. Conclusion: This review focuses on the various plants that have been reported to be effective in the treatment of diabetes. The survey shows that plants from the Rubiaceae, Labiataceae, Meliaceae, Hypoxidaceae and Cucurbitaceae families are commonly used by traditional healers in Ibadan for the treatment of diabetes mellitus. DOI: http://dx.doi.org/10.3126/ajms.v6i5.10480Asian Journal of Medical Sciences Vol.6(5) 2015 36-40
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Ojha, Shreesh, Juma Alkaabi, Naheed Amir, Azimullah Sheikh, Ahmad Agil, Mohamed Abdelmonem Fahim, and Abdu Adem. "Withania coagulansFruit Extract Reduces Oxidative Stress and Inflammation in Kidneys of Streptozotocin-Induced Diabetic Rats." Oxidative Medicine and Cellular Longevity 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/201436.

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The present study was carried out to investigate the changes in oxidative and inflammatory status in streptozotocin-induced diabetic rat’s kidneys and serum following treatment withWithania coagulans, a popular herb of ethnomedicinal significance. The key markers of oxidative stress and inflammation such as inflammatory cytokines (IL-1β, IL-6, and TNF-α) and immunoregulatory cytokines (IL-4 and IFN-γ) were increased in kidneys along with significant hyperglycemia. However, treatment of four-month diabetic rats withWithania coagulans(10 mg/kg) for 3 weeks significantly attenuated hyperglycemia and reduced the levels of proinflammatory cytokines in kidneys. In addition,Withania coagulanstreatment restored the glutathione levels and inhibited lipid peroxidation along with marked reduction in kidney hypertrophy. The present study demonstrates thatWithania coagulanscorrects hyperglycemia and maintained antioxidant status and reduced the proinflammatory markers in kidneys, which may subsequently reduce the development and progression of renal injury in diabetes. The results of the present study are encouraging for its potential use to delay the onset and progression of diabetic renal complications. However, the translation of therapeutic efficacy in humans requires further studies.
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Sharma, Hari Devi, Janardan Lamichhane, Smriti Gurung, and Balkumari Oliya. "Ethnobotanical and Phytochemical Study of Houttuynia cordata Thunb: A Review." BMC Journal of Scientific Research 6, no. 1 (December 22, 2023): 55–62. http://dx.doi.org/10.3126/bmcjsr.v6i1.60954.

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Houttuynia cordata Thunb. is a medicinal herb belonging to a family Saururaceae distributed in East Asian Country. It has long been used as edible vegetable and traditional medicine in China, Korea, Japan and Vietnam. Many studies describe Houttuynia cordata as predominant in bioactive compounds such as volatile oils, flavonoids, alkaloids, terpenoids, polyphenols, steroid and polysaccharides. H. cordata has varieties of pharmacological properties including antibacterial, anti-inflammatory, antiviral antioxidative, anticancer and antimutagenic effects. This review aimed to collect the comprehensive information on efficacy of Houttuynia cordata with its ethnobotanical value and also provide knowledge into disease prevention and treatment. This study summarizes detailed information about ethnomedicinal value of H. cordata from searching the keywords “Uses of Houttuynia” in Google Scholor, Pubmed, Science direct and screened out articles related to ethnobotanical value. The review concluded that H. cordata has significant potential for use in pharmaceuticals and functional foods, given its numerous health benefits and low toxicity. This study suggests that, it is necessary to identify actual bioactive metabolites and understand pattern of traditional use of the plant in different location of Nepal.
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Alfred Maroyi. "Chemical properties, biological activities and ethnomedicinal uses of Maerua pseudopetalosa: A famine food species of tropical Africa." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (December 21, 2020): 7889–97. http://dx.doi.org/10.26452/ijrps.v11i4.4686.

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Maerua pseudopetalosa (Gilg & Gilg-Ben.) DeWolf is a perennial herb or subshrub collected from the wild as a food plant or traditional medicine. Maerua pseudopetalosa occurs naturally from Senegal, east to Eritrea and Ethiopia, through South Sudan, Sudan, East Africa, south to the Democratic Republic of Congo (DRC). This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of M. pseudopetalosa. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the fruit, leaf and root infusion and/or decoction of M. pseudopetalosa are mainly used as a stimulant and to restore physical strength and vitality, and traditional medicine for chest pains, breast cancer and cough. Phytochemical compounds identified from aerial parts, fruits, roots, seeds and tubers of M. pseudopetalosa include quaternary ammonium compounds, alkaloids, amino acids, betaines, cardiac glycosides, fatty acids, essential oils, flavonoids, phenolics, sterols and tannins. Preliminary ethnopharmacological research revealed that aerial parts, roots and tubers of M. pseudopetalosa have antibacterial, antifungal, antihyperglycemic, antioxidant, α-glucosidase inhibitory, pancreatic lipase inhibitory and cytotoxicity activities. Maerua pseudopetalosa should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.
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Sarkar, Chandan, Milon Mondal, Bilkis Khanom, Md Monir Hossain, Md Solayman Hossain, Antoni Sureda, Muhammad Torequl Islam, et al. "Heliotropium indicum L.: From Farm to a Source of Bioactive Compounds with Therapeutic Activity." Evidence-Based Complementary and Alternative Medicine 2021 (June 1, 2021): 1–21. http://dx.doi.org/10.1155/2021/9965481.

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This study aimed to summarize the available data on the ethnomedicinal and phytopharmacological activities of Heliotropium indicum L. based on database reports. For this purpose, an up-to-date literature search was carried out in the Google Scholar, Scopus, Springer Link, Web of Science, ScienceDirect, ResearchGate, PubMed, Chem Spider, Elsevier, BioMed Central, and patent offices (e.g., USPTO, CIPO, NPI, Google patents, and Espacenet) for the published materials. The findings suggest that the plant contains many important phytochemicals, including pyrrolizidine alkaloids, indicine, echinitine, supinine, heleurine, heliotrine, lasiocarpine, acetyl indicine, indicinine, indicine N-oxide, cynoglossine, europine N-oxide, heleurine N-oxide, heliotridine N-oxide, heliotrine N-oxide, heliotrine, volatile oils, triterpenes, amines, and sterols. Scientific reports revealed that the herb showed antioxidant, analgesic, antimicrobial, anticancer, antituberculosis, antiplasmodial, anticataract, antifertility, wound healing, antiinflammatory, antinociceptive, antihyperglycemic, anthelmintic, diuretic, antitussive, antiglaucoma, antiallergic, and larvicidal activity. In conclusion, in vitro studies with animal models seem to show the potential beneficial effects of H. indicum against a wide variety of disorders and as a source of phytotherapeutic compounds. However, clinical studies are necessary to confirm the effects observed in animal models, determine the toxicity of the therapeutic dose and isolate the truly bioactive components.
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Drobnik, Jacek, and Adam Stebel. "Four Centuries of Medicinal Mosses and Liverworts in European Ethnopharmacy and Scientific Pharmacy: A Review." Plants 10, no. 7 (June 25, 2021): 1296. http://dx.doi.org/10.3390/plants10071296.

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(1) Medicinal use of bryophytes dates to ancient times, but it has always been marginal due to their small size, difficult identification, lack of conspicuous organs which would attract attention (flowers, fruits) and insipid taste of the herb. The earliest testimonies of their medical use come from the 1500s. The interest in medicinal bryophytes diminished considerably in the 1880s, except for Sphagnum spp., which became a source of dressing material. The second half of the 20th century saw the revival of the study of bryophyte chemistry. (2) Historical printed sources from 1616 to 1889 were queried. Bryophyte species found were taxonomically identified and presented against the background of their confirmed properties and ecology. The study was supplemented with historical vs. modern ethnomedicinal data. (3) In 26 publications, 28 species were identified. Modern usage was known for 10 of them. Medicinal properties of 16 species were confirmed. (4) Species of wide geographical distribution range were (or are still being) used in local folk medicines. Historical ethnobiological and ethnopharmaceutical uses of them are sometimes convergent with their confirmed properties, mostly external (as antimicrobial or cytotoxic remedies).
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Niranjana, M. R., and J. E. Thoppil. "ANTI INFLAMMATORY EFFECT AND GC-MS METABOLOME PROFILING OF Curcuma haritha Mangaly and M. Sabu – AN ENDEMIC HERB OF KERALA, SOUTH INDIA." Applied Biological Research 26, no. 1 (March 23, 2024): 66–77. http://dx.doi.org/10.48165/abr.2024.26.01.9.

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Curcuma haritha (Zingiberaceae) is a less explored endemic ethnomedicinal herb of north Kerala (India). The aim of present study was to evaluate the anti inflammatory potential and phytochemical profile of methanolic rhizome extract of C. haritha. The preliminary assays performed were, the proteinase inhibition and the protein denaturation inhibition tests, followed by cyclooxygenase, lipoxygenase, iNOS and cellular nitrite activity/expression assays in LPS stimulated RAW 264.7 cells. The toxicity of the extract was studied using MTT assay and the expression of COX-2 inflammatory protein in treated cells was determined by indirect ELISA. The phytochemical profiling was done by GC-MS analysis. All the assays revealed a dose-dependent anti-inflammatory effect in vitro. The inhibition of inflammatory enzymes, COX-2, Lox and iNOS were observed as 62.16 ± 0.49, 57.25 ± 1.98 and 56.74 ± 2.73%, respectively, at maximum concentration (100 µg mL-1). The cellular nitrite levels and expression of COX-2 mediator protein also decreased in treated cells proving the anti inflammatory effect of the extract. GC-MS screening revealed the presence of 54 phytoconstituents including anti-inflammatory compounds like curcumenol, chamazulene, etc., Therefore, in the light of above results, C. haritha can be considered as a potential anti-inflammatory drug source plant.
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Chakraborti, Saswati, Sangram Sinha, and Rabindra K. Sinha. "High-frequency induction of multiple shoots and clonal propagation from rhizomatous nodal segments of Houttuynia cordata Thunb.—An ethnomedicinal herb of India." In Vitro Cellular & Developmental Biology - Plant 42, no. 5 (September 2006): 394–98. http://dx.doi.org/10.1079/ivp2006797.

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Fazmiya, Mohamed Joonus Aynul, Arshiya Sultana, Khaleequr Rahman, Md Belal Bin Heyat, Sumbul, Faijan Akhtar, Salabat Khan, and Seth Christopher Yaw Appiah. "Current Insights on Bioactive Molecules, Antioxidant, Anti-Inflammatory, and Other Pharmacological Activities of Cinnamomum camphora Linn." Oxidative Medicine and Cellular Longevity 2022 (October 7, 2022): 1–23. http://dx.doi.org/10.1155/2022/9354555.

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C. camphora is a renowned traditional Unani medicinal herb and belongs to the family Lauraceae. It has therapeutic applications in various ailments and prophylactic properties to prevent flu-like epidemic symptoms and COVID-19. This comprehensive appraisal is to familiarize the reader with the traditional, broad applications of camphor both in Unani and modern medicine and its effects on bioactive molecules. Electronic databases such as Web of Science, PubMed, Google Scholar, Scopus, and Research Gate were searched for bioactive molecules, and preclinical/clinical research and including 59 research and review papers up to 2022 were retrieved. Additionally, 21 classical Unani and English herbal pharmacopeia books with ethnomedicinal properties and therapeutic applications were explored. Oxidative stress significantly impacts aging, obesity, diabetes mellitus, depression, and neurodegenerative diseases. The polyphenolic bioactive compounds such as linalool, borneol, and nerolidol of C. camphora have antioxidant activity and have the potential to remove free radicals. Its other major bioactive molecules are camphor, cineole, limelol, safrole, limonene, alpha-pinene, and cineole with anti-inflammatory, antibacterial, anxiolytic, analgesic, immunomodulatory, antihyperlipidemic, and many other pharmacological properties have been established in vitro or in vivo preclinical research. Natural bioactive molecules and their mechanisms of action and applications in diseases have been highlighted, with future prospects, gaps, and priorities that need to be addressed.
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Ong, Wei-Yi, Deron R. Herr, Grace Y. Sun, and Teng-Nan Lin. "Anti-Inflammatory Effects of Phytochemical Components of Clinacanthus nutans." Molecules 27, no. 11 (June 4, 2022): 3607. http://dx.doi.org/10.3390/molecules27113607.

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Recent studies on the ethnomedicinal use of Clinacanthus nutans suggest promising anti-inflammatory, anti-tumorigenic, and antiviral properties for this plant. Extraction of the leaves with polar and nonpolar solvents has yielded many C-glycosyl flavones, including schaftoside, isoorientin, orientin, isovitexin, and vitexin. Aside from studies with different extracts, there is increasing interest to understand the properties of these components, especially regarding their ability to exert anti-inflammatory effects on cells and tissues. A major focus for this review is to obtain information on the effects of C. nutans extracts and its phytochemical components on inflammatory signaling pathways in the peripheral and central nervous system. Particular emphasis is placed on their role to target the Toll-like receptor 4 (TLR4)-NF-kB pathway and pro-inflammatory cytokines, the antioxidant defense pathway involving nuclear factor erythroid-2-related factor 2 (NRF2) and heme oxygenase 1 (HO-1); and the phospholipase A2 (PLA2) pathway linking to cyclooxygenase-2 (COX-2) and production of eicosanoids. The ability to provide a better understanding of the molecular targets and mechanism of action of C. nutans extracts and their phytochemical components should encourage future studies to develop new therapeutic strategies for better use of this herb to combat inflammatory diseases.
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Ahmed, Fakhruddin Ali, Anisur Rahman, Sanzida Mubassara, and Gazi Mosharof Hossain. "Ethnobotany and antibacterial potentiality of Blumea lacera L. from Sundarban Mangrove forest of Bangladesh." Jahangirnagar University Journal of Biological Sciences 3, no. 2 (June 19, 2016): 17–24. http://dx.doi.org/10.3329/jujbs.v3i2.28282.

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Indigenous knowledge on the utilization of Blumea lacera L. by the interim people as well as ethnic communities living at the vicinity of Sundarban mangrove forest of Bangladesh were documented through survey, interview, collection and identification. Native people of Sundarban use the herb in bleeding piles. Leaf of the plant was found to be the most useful part for ethnomedicinal use. Generally, leaves of B. lacera have been used to treat most kinds of colds. Warm leaf paste used as diuretic whereas leaf paste with black pepper powder was found to apply in dog bite. Furthermore, B. lacera collected from Sundarban mangrove habitat as well as from natural plain land habitat (JU campus) were subjected to a comparative analysis of antibacterial activity. Antibacterial study from the present experiment suggested that the ethyl acetate fraction of B. lacera, irrespective of habitat choice, was active against the gram-positive bacteria Bacillus cereus. The methanol fraction of Sundarban sample showed significant dose dependent increase in antibacterial activity against the gram-negative bacteria Serratia sp., Proteus mirabilis, Salmonella typhi and Vibrio cholera while the JU sample did not produce any inhibition zone. The n-hexane fractions of both type plant samples were entirely non-responsive to the bacterial growth.Jahangirnagar University J. Biol. Sci. 3(2): 17-24, 2014 (December)
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