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1

Micaelo, Maïté, Pascal Rasmy, Marlène Amara, Juliette Lambert, Aymeric Coutard, and Béatrice Pangon. "Erysipelothrix rhusiopathiae bacteremia: a challenging diagnosis!" Annales de biologie clinique 74, no. 5 (September 2016): 613–15. http://dx.doi.org/10.1684/abc.2016.1183.

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Takeshi, Kouichi, Souichi Makino, Tetsuya Ikeda, Noriko Takada, Atsushi Nakashiro, Kazunori Nakanishi, Keiji Oguma, Yoshinobu Katoh, Hiroyuki Sunagawa, and Tohru Ohyama. "Direct and Rapid Detection by PCR ofErysipelothrix sp. DNAs Prepared from Bacterial Strains and Animal Tissues." Journal of Clinical Microbiology 37, no. 12 (1999): 4093–98. http://dx.doi.org/10.1128/jcm.37.12.4093-4098.1999.

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A PCR method for rapid screening of Erysipelothrix spp. in the slaughterhouse was carried out by using four species-specific sets of oligonucleotide primers after initial amplification with the primer set MO101-MO102, which amplifies the 16S rRNA sequences of all four Erysipelothrix species. The DNA sequences coding for the rRNA gene cluster, including 16S rRNA, 23S rRNA, and the noncoding region downstream of 5S rRNA, were determined in order to design primers for the species-specific PCR detection system. The homology among the 4.5-kb DNA sequences of the rRNA genes ofErysipelothrix rhusiopathiae serovar 2 (DNA Data Bank of Japan accession no. AB019247), E. tonsillarum serovar 7 (accession no. AB019248), E. rhusiopathiae serovar 13 (accession no. AB019249), and E. rhusiopathiae serovar 18 (accession no. AB019250) ranged from 96.0 to 98.4%. The PCR amplifications were specific and were able to distinguish the DNAs from each of the four Erysipelothrix species. The results of PCR tests performed directly with tissue specimens from diseased animals were compared with the results of cultivation tests, and the PCR tests were completed within 5 h. The test with this species-specific system based on PCR amplification with the DNA sequences coding for the rRNA gene cluster was an accurate, easy-to-read screening method for rapid diagnosis of Erysipelothrix sp. infection in the slaughterhouse.
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3

Meier, Simone Martina, Jan Kottwitz, Dagmar I. Keller, and Sarah Albini. "Erysipelothrix rhusiopathiae infection by geese to human transmission." BMJ Case Reports 14, no. 5 (May 2021): e240073. http://dx.doi.org/10.1136/bcr-2020-240073.

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Erysipelothrix rhusiopathiae transmission to human is often occupation-related, but in most cases, a detailed case history is missing. This case report is based on an interdisciplinary approach and includes a thorough medical record. A 58-year-old laboratory technician working on geese necropsy cut open her glove at a rib fragment of a goose and subsequently noticed a slowly progressive, reddish skin alteration in the particular region of the hand. Bacteriological investigations on the geese revealed septicaemia due to E. rhusiopathiae and therefore substantiated the diagnosis of the patient. The infectious agent could not be cultured from the patient; however, antibiotic susceptibility testing was performed using the goose isolate. An entire follow-up until full recovery of the patient was conducted. Zoonotic infections possibly have a significant impact on certain occupations. This case report analyses a rare but important zoonotic infection to create awareness of this in physicians caring for human patients.
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4

Rocha, Marion P., Paulo R. S. Fontoura, Suzana N. B. Azevedo, and Armando M. V. Fontoura. "Erysipelothrix endocarditis with previous cutaneous lesion: report of a case and review of the literature." Revista do Instituto de Medicina Tropical de São Paulo 31, no. 4 (August 1989): 286–89. http://dx.doi.org/10.1590/s0036-46651989000400013.

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This report describes the first documented case of Erysipelothrix rhusiopathiae endocarditis in Latin America. The patient was a 51-years-old male, moderate alcoholic, with a previous history of aortic failure. He was used to fishing and cooking as a hobby and had his left hand wounded by a fish-bone. The disease began with erysipeloid form and developed to septicemia and endocarditis. He was treated with antibiotics and surgery for aortic valve replacement. There are only 46 cases of E. rhusiopathiae endocarditis reported to date. The authors wonder if several other cases might go unreported for lack of microbiological laboratorial diagnosis.
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5

Seelig, U., R. Klopfleisch, C. Weingart, B. Walther, A. Luebke-Becker, and L. Brunnberg. "Septic polyarthritis caused by Erysipelothrix rhusiopathiae in a dog." Veterinary and Comparative Orthopaedics and Traumatology 23, no. 01 (2010): 71–73. http://dx.doi.org/10.3415/vcot-09-05-0058.

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SummaryA 14-month-old, male German Shepherd dog was admitted with a six-week history of lameness and swelling of the right hindlimb. Clinical examination revealed polyarthritis, fever, petechiae and ecchymoses of the abdominal skin and prepuce. The haematology and blood chemistry were indicative of sepsis. Mediolateral radiographic views of both of the stifle joints revealed signs of bilateral articular capsule swelling. The radiographical, bacteriological and necropsy findings confirmed a diagnosis of septic polyarthritis due to infection with Erysipelothrix rhusiopathiae.
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6

Shimoji, Yoshihiro, Yasuyuki Mori, Koji Hyakutake, Tsutomu Sekizaki, and Yuichi Yokomizo. "Use of an Enrichment Broth Cultivation-PCR Combination Assay for Rapid Diagnosis of Swine Erysipelas." Journal of Clinical Microbiology 36, no. 1 (1998): 86–89. http://dx.doi.org/10.1128/jcm.36.1.86-89.1998.

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We have previously described the creation by Tn916mutagenesis of avirulent transposition mutants from a highly virulent strain of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas. In this study, we cloned a 2.2-kb DNA fragment which flanked the Tn916 insertion in an avirulent mutant (strain 33H6) and evaluated the possibility that this region could be used for the specific detection of E. rhusiopathiae. According to the sequences of this region, oligonucleotide primers were designed to amplify a 937-bp fragment of the E. rhusiopathiae chromosome by PCR. The specificity of the PCR was investigated by analyzing 64 strains of Erysipelothrixspecies and 27 strains of other genera different fromErysipelothrix. A 937-bp DNA fragment could be amplified from all E. rhusiopathiae strains tested, and no amplification was observed by using DNAs from the other species tested. To make a rapid and definite diagnosis of swine erysipelas in slaughterhouses, we developed an enrichment broth cultivation-PCR combination assay, which used a commercially available DNA extraction kit, to identify E. rhusiopathiae in the specimens from swine with arthritis. After samples were enriched in selective broth culture, detection of E. rhusiopathiae was tested by either conventional methods or the PCR. Of 102 samples tested, 15 samples were positive by conventional methods and 12 of the 15 samples were positive by the PCR. The detection limit of the PCR was 103 CFU per reaction mixture for the PCR-positive samples. These results indicate that this PCR technique could be used as a first-line screening technique for the specific detection of E. rhusiopathiae in specimens.
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7

Patel, Krutika, S. Shawn Liu, Sandhya Dasaraju, and J. Elliot Carter. "Erysipelothrix rhusiopathiae Native Value Endocarditis: A Unique Case Presentation." American Journal of Clinical Pathology 152, Supplement_1 (September 11, 2019): S129—S130. http://dx.doi.org/10.1093/ajcp/aqz125.004.

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Abstract ER is a facultative, non-spore-forming, non-acid-fast, gram-positive bacillus. It is a ubiquitous commensal in wild and domestic animals, birds, and fish and has an enormous economic impact on animal husbandry and marine industry, causing animal erysipelas. Human infections are extremely rare, occupationally acquired zoonosis. Human infections are acquired through wounds, contact with sick animals, and carriers and commonly includes localized or generalized self-limited cutaneous erysipelas. Seldom, systemic infection and septicemia occur. We present here, a case of a 50-year-old immunocompetent retired shipyard welder who enjoyed fishing in his spare time and presented to the emergency room with fever, chest pain, significant weight loss, and dry cough lasting 2 to 3 months. He did not report any bites or injuries, intravenous drug abuse, or travel history. An echocardiogram showed mobile vegetation on aortic valve with severe regurgitation. Blood and tissue cultures grew E rhusiopathiae, identified by MALDI-TOF method. He was treated with empiric vancomycin followed by penicillin and aortic valve replacement with a mechanical valve. Cases of E rhusiopathiae–induced native valve endocarditis and septicemia are extremely infrequent in immunocompetent individuals, especially when occupation-related exposure is not noted. Even after surgery, it may entail fatality rates as high as 40%, higher than endocarditis caused by other bacteria. While some current reports suggest incidences of human infections are declining due to technological advances in animal industry, infection still occurs in specific environments. Additionally, it may be underdiagnosed due to its resemblance to other infections and problems encountered in isolation and identification. The natural resistance of E rhusiopathiae to glycopeptides underlines the importance of a prompt microbiological diagnosis of such an uncommon human infection, especially when presented in an unusual clinical presentation. Clinicians and microbiologists working with exposed population should be aware of this microbe and its manifestations.
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8

Schoiswohl, J., J. Spergser, and J. Kofler. "Polyarthritis caused by Erysipelothrix rhusiopathiae in three Austrian sheep flocks – diagnosis, treatment and management measures." Schweiz Arch Tierheilkd 162, no. 12 (December 5, 2020): 771–80. http://dx.doi.org/10.17236/sat00282.

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9

Altibi, Ahmed M., Mohammed Khalid, Vivek Kak, and Brijesh Patel. "Native valve endocarditis caused by ErysipelothrixRhusiopathiae: presenting with refractory heart failure and requiring surgical valve replacement—report on a rare zoonosis." BMJ Case Reports 12, no. 12 (December 2019): e230891. http://dx.doi.org/10.1136/bcr-2019-230891.

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Erysipelothrix Rhusiopathiae is a Gram-positive bacillus that is ubiquitous in nature. The bacterium is a zoonotic pathogen known to infect wild and domestic animals. Human infections, however, are uncommon and typically present with localised or generalised cutaneous lesions. Systemic infection in the form of bacteraemia with seeding to various organs is the least common form of the disease. Infections in humans tend to be associated with occupational exposure and close contact with animals. Clinical data of a 61-year-old male patient with Gram-positive bacilli bacteraemia and E.Rhusiopathiae-induced endocarditis are presented here. The patient presented with refractory congestive heart failure secondary to severe acute aortic regurgitation mandating surgical valve replacement. The described case has special clinical merit given the lack of fever and leukocytosis, absence of erysipeloid cutaneous manifestations and refractoriness to medical management. E. Rhusiopathiae should be considered in the differential diagnosis for Gram-positive bacilli bacteraemia and endocarditis. In the proper clinical setting, occupational exposure and animal contacts are helpful clues to raise suspicion for this bacillus. The high mortality associated with the pathogen should urge for early identification and initiation of antimicrobial treatment.
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10

Volard, Bertrand, Loïc Mignot, Emmanuel Piednoir, Christophe de Champs, Anne Limelette, and Thomas Guillard. "Systemic Erysipelothrix rhusiopathiae infection not associated with endocarditis highlighting bacteriological diagnosis difficulties Case report and literature review." Annales de biologie clinique 74, no. 3 (May 2016): 306–12. http://dx.doi.org/10.1684/abc.2016.1140.

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11

Marshall, Kalie R., Stuart A. Walton, Megan Boyd, Bradley Bishop, James Wellehan, William Craft, and Domenico Santoro. "Erysipeloid lesions caused by Erysipelothrix rhusiopathiae in a dog: clinical and histopathological findings, molecular diagnosis and treatment." Veterinary Dermatology 30, no. 5 (July 31, 2019): 434. http://dx.doi.org/10.1111/vde.12773.

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12

Giménez-Lirola, Luis G., Chao-Ting Xiao, Marissa Zavala, Patrick G. Halbur, and T. Opriessnig. "Improving ante mortem diagnosis of Erysipelothrix rhusiopathiae infection by use of oral fluids for bacterial, nucleic acid, and antibody detection." Journal of Microbiological Methods 92, no. 2 (February 2013): 113–21. http://dx.doi.org/10.1016/j.mimet.2012.11.014.

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13

Sharifuddin, Aasiah Ahmad, and Krishnalatha Buandasan. "A case of panophthalmitis with orbital cellulitis related to Erysipelothrix rhusiopathiae infection." Malaysian Journal of Ophthalmology 2, no. 1 (April 22, 2020): 48–54. http://dx.doi.org/10.35119/myjo.v2i1.39.

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Erysipelothrix rhusiopathiae is a zoonotic pathogen that rarely causes infection in humans. Human infection occurs as a result of either contact with animals, their meat products, or waste. The septicaemic form of Erysipelothrix rhusiopathiae infection can subsequently lead to complications which include endocarditis, intracranial abscess, liver abscess, and in this case, panophthalmitis. The incidence of Erysipelothrix rhusiopathiae infection however, may be under-diagnosed due the resemblance it bears to other bacteria. Here we report a case of panophthalmitis in a 57-year-old Malay woman with no previous medical illness caused by Erysipelothrix rhusiopathiae, which rarely causes ocular infection.
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14

Balkhair, A., H. Al Lawati, M. Al Riyami, T. Alameddine, M. Al Amin, and B. Al Adawi. "Erysipelothrix rhusiopathiae endocarditis diagnosed by broad range 16s rRNA PCR gene sequencing." IDCases 18 (2019): e00584. http://dx.doi.org/10.1016/j.idcr.2019.e00584.

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15

Mutalib, Ahmed A., John M. King, and Patrick L. McDonough. "Erysipelas in Caged Laying Chickens and Suspected Erysipeloid in Animal Caretakers." Journal of Veterinary Diagnostic Investigation 5, no. 2 (April 1993): 198–201. http://dx.doi.org/10.1177/104063879300500210.

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Erysipelas was diagnosed in 2 succeeding caged layer flocks housed in the same building and was characterized clinically by sudden death. At necropsy, lesions comprised generalized congestion, hemorrhages in the skeletal muscles and visceral organs, and swelling of liver, spleen, and kidney with or without large irregular zones of necrosis. Focal to massive hepatic necrosis was seen histologically with minimal or no inflammatory reaction. Erysipelothrix rhusiopathiae was cultured from internal organs of affected birds in both outbreaks. Medication with penicillin in the feed controlled the mortality, but relapse occurred after cessation of medication. Two attendants who handled the dead birds in this building developed a painful localized infection of the fingers that later spread to the regional lymph node. The infection responded when antibiotic therapy for erysipeloid was initiated.
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16

Sankar, S., P. S. Reshma, N. Sarika, M. R. Roshin, R. Niranjana, M. Mini, N. D. Nair, K. Krithiga, A. P. Usha, and E. D. Benjamin. "A report of swine erysipelas infection in an organised farm in Kerala." Indian Journal of Animal Research, of (January 7, 2019). http://dx.doi.org/10.18805/ijar.b-3689.

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Erysipelothrix rhusiopathiae is an established animal pathogen causing erysipelas in animals and occasionally it causes zoonotic skin infections in humans, known as erysipeloid. The present study was aimed to investigate the cause of sudden mortality in a batch of gilts in an organised farm in Thrissur district of Kerala. The heart swabs and tissue samples (spleen, liver, lungs, and heart) collected during post-mortem examination yielded growth of small Gram positive, non-capsulated, spore forming pleomorphic bacilli. Based on cultural, morphological and biochemical characteristics, these isolates were identified as E. rhusiopathiae. Furthermore, the isolates were subjected to Erysipelothrix specific 16S rRNA based polymerase chain reaction. The isolates were sequenced for further confirmation. The isolates were confirmed as E. rhusiopathiae by phenotypic and genotypic characterisation. Timely diagnosis of the disease helped to identify the possible source of infection. This study highlights the importance of timely identification of E. rhusiopathiae infection in an outbreak; thereby adequate strategies can be implemented to control the infection.
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Cabrera-García, Angela I., Franziska Müller, Frauke S. Rödler, Florian Traub, and Romy M. Heilmann. "Infective endocarditis due to Erysipelothrix rhusiopathiae in a dog – a case report." BMC Veterinary Research 16, no. 1 (September 10, 2020). http://dx.doi.org/10.1186/s12917-020-02546-6.

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Abstract Background Infective endocarditis is a rare but severe condition associated with a high mortality rate in small animal patients. This condition is caused by a microbial (most often bacterial) infection of the valvular portion of the endocardium, from which proliferative and/or erosive lesions on the cardiac valves or immediately adjacent structures develop. The two most commonly affected cardiac valves are the aortic and mitral valves. Case presentation We report the clinical case of a 4-year old male neutered Bull terrier, 27.6 kg, body condition score 4/9, that presented with a 3-months history of pyrexia and general weakness. The patient history also revealed a transient left hind limb lameness (grade 2/4), which coincided with the onset of clinical signs about 3 months before presentation. On physical examination, a left-sided systolic heart murmur (grade 3/6) with the same intensity at the left heart base and apex, and an irregularly irregular heart rhythm were noted. Electrocardiography showed ventricular premature complexes, and echocardiography revealed lesions consistent with endocarditis involving the aortic and mitral valve. Bacterial culture of blood yielded a positive result, and the organism isolated was identified as Erysipelothrix rhusiopathiae. The extended patient history revealed that the dog lived close to a farm housing pigs and other livestock. Conclusion We report a rare case of the premortal diagnosis of infective bacterial endocarditis in a dog due to E. rhusiopathiae infection. Most reports about this condition are from necropsy series. This clinical case report emphasizes that E. rhusiopathiae infection and bacteremia should be considered as a differential diagnosis in dogs with suspected infective endocarditis, especially in dogs living in rural areas with access to livestock and particularly farm pigs. Also, particular emphasis should be placed on the zoonotic potential of this infectious disease.
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18

Cubas Atienzar, Ana I., Priscilla F. Gerber, and Tanja Opriessnig. "Use of the rSpaA415 antigen indicates low rates of Erysipelothrix rhusiopathiae infection in farmed cattle from the United States of America and Great Britain." BMC Veterinary Research 15, no. 1 (November 1, 2019). http://dx.doi.org/10.1186/s12917-019-2147-7.

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Abstract Background Clinical cases of Erysipelothrix rhusiopathiae, a zoonotic gram-positive bacterium, have been reported in many ruminant species, including in cattle, deer, moose and muskoxen. Fatal cases have been repeatedly reported in cattle over the years but to date there is only one Japanese study investigating the seroprevalence of this bacterium in cattle using the growth agglutination test (GAT). This technique is subjective, time-consuming, expensive and hazardous compared to modern serological tests such as enzyme-linked immunosorbent assays (ELISA) or the newly developed fluorescent microbead-based immunoassays (FMIA). Results The FMIA based on the surface protein SpaA (rSpaA415) antigen of E. rhusiopathiae developed in this study had an almost perfect agreement with the GAT (k = 0.83) and showed a sensitivity of 89.7% and a specificity of 92.9% when compared to the GAT. Overall, detection rates of E. rhusiopathiae antibody positive samples were 13.8% (51/370) in British herds and 6% (12/200) in US herds. Positive cattle were present in 34.3% (24/70) of the investigated British farms and in 34.7% (8/23) of the US farms with an on-farm prevalence of 7.1 to 100% for the British farms and 8.3–30% for the US farms. Conclusions FMIA is a fast, safe and economic alternative to the GAT for the diagnosis of E. rhusiopathiae in cattle. This work is the first seroprevalence study of E. rhusiopathiae in healthy farmed cattle in Great Britain and the US and revealed that infection occurs at a low level. Further investigations to evaluate risks of zoonotic transmission when handling cattle are needed.
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19

Wabacha, J. K., G. K. Gitau, J. M. Nduhiu, A. G. Thaiya, P. M. F. Mbithi, and S. J. M. Munyua. "An outbreak of urticarial form of swine erysipelas in a medium-scale piggery in Kiambu District, Kenya : case reoprt." Journal of the South African Veterinary Association 69, no. 2 (July 12, 1998). http://dx.doi.org/10.4102/jsava.v69i2.818.

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This report concerns an outbreak that occurred during July/August 1997. Ten pigs from a herd of 181 pigs in a medium-scale, semi-closed piggery in Kiambu District, Kenya, contracted the clinical disease. The main clinical findings in affected pigs included: fever (40.5-41.8 oC), prostration, inappetence, dog-sitting posture, abortion, erythema and raised, firm to the touch and easily palpated light pink to dark purple diamond-shaped to square/rectangular spots on the skin around the belly and the back. Based on the pathognomonic skin lesions, a clinical diagnosis of swine erysipelas was made. The diagnosis was confirmed by the isolation of Erysipelothrix rhusiopathiae organisms from the blood and skin biopsies taken from the affected pigs. Response to treatment with a combination of procaine penicillin and dihydrostreptomycin at the dosage rate of 20 000 IU/kg body weight (based on procaine penicillin) for 3 days was good and all the affected pigs recovered fully. The farm was placed under quarantine to prevent spread of the disease.
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20

Habte, Dessalew, and Dessalew Tamir. "Swine Erysipelas; It’s Epidemiology, Diagnosis, Treatment and Control and Preventive Measures, Comprehensive Review." Journal of Clinical Epidemiology & Toxicology, March 31, 2021, 1–7. http://dx.doi.org/10.47363/jcet/2020(2)115.

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Erysipelas is an infectious disease seen mainly in growing pigs and characterized clinically by fever, arthritis, skin lesions and sudden death. The disease may be acute, subacute, or chronic. Swine erysipelas is a disease caused by a specific micro organ Erysipelothrix rhusiopathiae whic h is a zoonotic ubiquitous gram-positive bacterium that causes erysipelas in swine, mammals, birds and erysipeloid in humans. People in contact with animals, animal products or animal wastes are at greatest risk. The acute form of swine erysipelas may have been confused for other diseases in pigs which are characterized by acute symptoms such as sudden death (for example, African swine fever). It can be diagnosed by its clinical signs, necropsy findings, bacteriology, antimicrobial response, molecular and serological examinations. It is recommended to increase awareness of the disease among animal and human practitioners as treatment is easy and available and vaccination is possible. However, the disease is still unknown to local veterinarians, clinical doctors, meat inspectors, butchers and laboratory personnel. Proper hygiene, regular pork inspection, use of protective wear among people working/ in contact with animals should be promoted. The disease causes high economic loss in pig rearing areas and influences the public health being a severe zoonotic disease. So the objective of this review is to create a better understanding of the disease for proper control and prevention of the disease
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21

Silva, Ana P., George Cooper, Julia Blakey, Carmen Jerry, H. L. Shivaprasad, and Simone Stoute. "Retrospective Summary of Erysipelothrix rhusiopathiae Diagnosed in Avian Species in California (2000–19)." Avian Diseases 64, no. 4 (June 25, 2020). http://dx.doi.org/10.1637/aviandiseases-d20-00038.

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22

Silva, Ana P., George Cooper, Julia Blakey, Carmen Jerry, H. L. Shivaprasad, and Simone Stoute. "Retrospective Summary of Erysipelothrix rhusiopathiae Diagnosed in Avian Species in California (2000–19)." Avian Diseases 64, no. 4 (June 25, 2020). http://dx.doi.org/10.1637/aviandiseases-d20-00038.

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23

ALBERTON, G. C., E. P. BANDARRA, I. PIFFER, M. A. Z. MORES, M. A. C. PEREIRA, and M. T. YAMAMOTO. "EXAME ANATOMOPATOLÓGICO, MICROBIOLÓGICO, CITOLÓGICO E FÍSICO-QUÍMICO DAS ARTICULAÇÕES DE SUÍNOS ARTRÍTICOS NO MATADOURO." Archives of Veterinary Science 8, no. 1 (June 30, 2003). http://dx.doi.org/10.5380/avs.v8i1.4021.

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Estudou-se por meio de exames anatomopatológico, microbiológico, citológico e físico-químico, as articulações de 130 suínos abatidos em um matadouro localizado em Concórdia – SC. Os animais foram escolhidos de forma direcionada e as articulações foram classificadas macroscopicamente de acordo com as lesões presentes na membrana sinovial, cartilagem articular e no linfonodo regional. Dos 130 suínos escolhidos, 25 apresentavam-se com as articulações normais, 36 com artrite causada pela osteocondrose, 50 com artrite infecciosa e 19 com artrite traumática. Em todos os casos de artrite infecciosa havia reação do linfonodo regional e, da mesma forma, sempre que os linfonodos regionais estavam reativos, havia artrite infecciosa no membro relacionado. Dos 50 casos de artrite infecciosa, 40 (80%) eram assépticos, de sete (14%) foi isolado o Erysipelothrix rhusiopathiae e de três (6%), o Mycoplasma hyosynoviae, pela primeira vez isolado no Brasil. Nas demais categorias de artrite, não foram isolados nenhum agente infeccioso e nem visualizadas alterações nos linfonodos regionais. Conclui-se que as artrites infecciosas são acompanhadas de reação dos linfonodos regionais e as artrites causadas pela osteocondrose são estéreis. Pathological, microbiological, cytological and physical-chemical studies of joints from arthritic swines in the abattoir Abstract The joints of one hundred and thirty pigs from an abattoir in Concórdia - SC, were studied, by means of pathological, microbiological, cytological and physical-chemical procedures. The choice of the pigs was not made by random distribution and the joints were grouped grossly according of lesions of the synovial membrane, cartilage and of the draining lymph node. From 130 pigs, 36 showed lesions of osteochondrosis, 50 infectious arthritis, 19 traumatic arthritis and 25 normal joints. In all cases of infectious arthritis there was a reaction of the corresponding draining lymph node. Whenever the draining lymph node was reactive, there was infectious arthritis in the related limb. Of the 50 infectious arthritis, 40 (80%) were aseptic, 7 (14%) yielded Erysipelothrix rhusiopathiae and 3 (6%) yielded Mycoplasma hyosynoviae, for the first time isolated in Brazil. In the remaining arthritis categories, no infectious agents nor alterations in the draining lymph node was diagnosed.
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