Dissertations / Theses on the topic 'Epilepsy in children'
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Nuttycombe, Rachael Eileen. "Parenting children with epilepsy." Thesis, University of Hull, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440230.
Full textThomason, Kate Elizabeth. "Cognitive variiability in children with epilepsy." Thesis, University of Sheffield, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500107.
Full textLunn, Judith. "Social understanding in children with epilepsy." Thesis, Lancaster University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656313.
Full textStewart, Elizabeth Margaret. "Theory of Mind in Children with Epilepsy." Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20234.
Full textGascoigne, Michael. "Long-term memory in children with epilepsy." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10216.
Full textNeri, Marina Liberalesso 1980. "Avaliação neuropsicológica de crianças com epilepsia rolândica = funções executivas." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309169.
Full textTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
Made available in DSpace on 2018-08-19T22:11:29Z (GMT). No. of bitstreams: 1 Neri_MarinaLiberalesso_D.pdf: 1266603 bytes, checksum: 21ed75ba94dfafe79f7d15127e020891 (MD5) Previous issue date: 2012
Resumo: A epilepsia benigna da infância com pontas centrotemporais (EBIPCT) ou rolândica (ER) é a forma mais freqüente de epilepsia na infância e é classificada como sendo focal, genética e de evolução benigna. Apesar de não haver déficit intelectual, essas crianças podem apresentar alterações cognitivas específicas. O presente estudo teve como objetivos: identificar e descrever alterações de funções executivas em crianças com ER e verificar a influência de variáveis clínicas da epilepsia nas funções executivas. Os participantes foram submetidos à aplicação de testes de funções executivas. Foram incluídas crianças com diagnóstico clínico e eletroencefalográfico de ER. A maioria dos pacientes estava controlada e muitos deles encontravam-se sem medicação. Os resultados obtidos foram comparados com os de um grupo de crianças de um grupo-controle (GC) constituído de indivíduos normais, com idade e nível sócio-educacional semelhantes ao das crianças com epilepsia. Os dados coletados nos dois grupos foram analisados e comparados através dos testes estatísticos: Mann-Whitney, teste Qui-quadrado e teste Exato de Fisher. Os resultados mostraram que quanto aos dados numéricos crianças com ER obtiveram pior desempenho em cinco das seis categorias consideradas do Wisconsin Card Sorting Test (WCST): nº de erros, nº de erros perseverativos, nº de respostas perseverativas, nº de categorias completadas e nº de fracassos em manter o set. Considerando-se resultados categóricos crianças com ER obtiveram pior desempenho no Trail Making Test (TMT) parte B, no Teste de fluência verbal FAS e em três categorias do WCST: nº de erros, nº de erros perseverativos e nº de respostas perseverativas. Em relação à variável idade de início da epilepsia, crianças com início mais precoce apresentaram pior desempenho em um dos instrumentos utilizados quando comparadas com crianças com início mais tardio da epilepsia; em relação às demais variáveis da epilepsia, não foi possível qualquer tipo de análise; quanto às variáveis das crises, não houve diferença nos resultados obtidos pelos pacientes divididos em grupos. Diante desses resultados concluímos que: as crianças com ER apresentaram déficit em funções executivas quando comparadas com o grupo-controle; a bateria utilizada mostrou-se adequada para detecção das disfunções apresentadas pelas crianças com ER; em relação à variável da epilepsia idade de início, crianças com início mais precoce apresentaram pior desempenho do que crianças com início mais tardio da epilepsia; em relação às demais variáveis da epilepsia e às variáveis das crises, não houve diferença entre os dois grupos. Assim, nosso estudo segue a linha de raciocínio de que o termo benigno deve ser usado com cautela uma vez que nossos pacientes apresentaram déficits neuropsicológicos em funções executivas, independentemente da fase ativa da epilepsia e do uso de medicações
Abstract: The benign childhood epilepsy with centrotemporal spikes (EBIPCT) or rolandic epilepsy (RE) is the most common type of childhood epilepsy and is considered to be a focal, genetic and benign epilepsy. Although there is no intellectual deficit, these children may have specific cognitive impairments. This study aimed: to identify and describe changes in executive functions in children with RE and to verify the influence of clinical variables of epilepsy in executive functions. Participants were evaluated with tests to assess executive functions. We included children with clinical and EEG features of RE. Most patients were controlled and several were without medication. The results were compared with those of a control group (CG) comprised of normal subjects with age and socioeconomic level similar to that of the RE group. The data collected from both groups were analyzed and compared using statistical tests: Mann-Whitney, Chi-square and Fisher exact tests. The results showed that concerning the numerical data, children with RE had the worst performance in five of the six categories of the WCST: number of errors, number of perseverative errors, number of perseverative answers, number of completed categories and number of failures to maintain the set. Considering categorical results, children with RE had worse performance in Trail Making Test part B, Verbal fluency test FAS and three categories of the WCST: number of errors, number of perseverative errors and number of perseverative answers. Concerning the variable age of onset of epilepsy, children with earlier onset of epilepsy had a worse performance in one of the tools when compared with children with later onset of epilepsy; the other variables of epilepsy did not allow any analysis; considering seizure variables, there was no difference between the two groups. We conclude that: children with RE showed deficits in executive functions when compared with the control group; the set of tests was adequate to detect the dysfunctions presented by children with RE; in relation to the variable age of onset of epilepsy, children with earlier onset had a worse performance than children with later onset of epilepsy; concerning other epilepsy and seizure variables, there was no difference between the two groups. Thus, our study is in keeping with the idea that the term benign should be cautiously used since our patients had neuropsychological deficits in executive functions regardless of the active phase of epilepsy and the use of medications
Doutorado
Ciencias Biomedicas
Doutor em Ciências Médicas
Beresford, Bryony. "Coping with epilepsy in childhood : an examination into factors mediating adjustment in children with epilepsy." Thesis, University of Exeter, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316379.
Full textCorrigan, Fiona MacDonald. "Sleep and forgetting in children with genetic generalised epilepsy." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6695/.
Full textCostolo, Megan. "Evidence-Based Intervention for Families of Children with Epilepsy." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/203001.
Full textParker, Alasdair Patrick John. "The investigation and management of children with epileptic encephalopathies." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391613.
Full textOliveira, Ana Valeria Duarte. "Avaliação do impacto da cirurgia de epilepsia no desenvolvimento de crianças com epilepsia refratária." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17140/tde-22082017-170746/.
Full textEpilepsy is a disease of the brain defined by at least two unprovoked seizures occurring 24 h apart, one unprovoked seizure and a probability of further seizures like the general recurrence risk (at least 60%) after two unprovoked seizures, occurring over the next 10 years or diagnosis of an epilepsy syndrome. After epilepsy diagnosis, there are situations where patients do not respond to drug treatment, developing one seizure per month for a minimum of 2 years. If during this period two or three antiepileptic drugs different used as monotherapy or in combination, a condition known as drug-resistant epilepsy. Epilepsy surgery is an option for children with drug-resistant epilepsy acting on the seizure control seizures and, potentially on neuropsychomotor development. In this study, we evaluated clinical variables such as epilepsy age of onset, epilepsy duration, seizure frequency, etiology and adaptive behavior scale of Vineland to characterize aspects related to age equivalence through the domains of communication, socialization, daily skills and motor skills pre- and post-surgical period. Our intention was to determine the impact of epilepsy surgery on the performance of patients in these areas evaluated by Vineland. Thus, we found that the seizure free group participants showed better cognitive performance in the second evaluation, compared to the group that not seizure controlled. The clinical variable duration of epilepsy influenced the age equivalence and standard Vineland scores in the preoperative period, being considered determinant for the neuropsychomotor delay of patients submitted to epilepsy surgery. Regarding the predictive factors of improvement of postoperative crises, it was observed that Engel and surgery were the variables considered significant. The majority of the patients (63.9%) in the second postoperative evaluation still had seizures or did not improve. The findings of the research on the impact of crises on neuropsychomotor were that in the first evaluation 21.3 months after surgery there was a below-expected gain of only 4.4 months of age equivalence, not showing improvement in the short term after surgery, independent of control crisis. After 41.3 months of the surgical procedure, the patients presenting with seizure control had significant adaptive gains of 15 months when compared to those without seizure control. In the latter patients, the age equivalence remained practically stable with an increase of o preoperative only 3 months, analyzing the phases pre and postoperative evaluation
Alkhaldi, Hani M. "Intractable epilepsy in South African children based on criteria defined by the international league against epilepsy (ILAE)." Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/6018.
Full textReed, Mary Poyner. "Parental Caregivers' Description of Caring for Children with Intractable Epilepsy." Thesis, Boston College, 2013. http://hdl.handle.net/2345/3153.
Full textThe objective of this study was to describe the parental perspective of caring for a child with intractable epilepsy. The purpose of this study was twofold: (1) to describe the caregiver transitions from caring for a healthy child to caring for a child with intractable epilepsy, and (2) to study families that provide caregiving, to identify the challenges, and learn how they address the intricacies and nuances of caring for a child with intractable epilepsy. The specific research questions that guide this study were: (1) What do parents of children with epilepsy find helpful or challenging during transitions from caring for a healthy child to a child with intractable epilepsy? (3) What factors enable parents to transition from caring for a healthy child to a child with intractable epilepsy? The research design used qualitative descriptive design and was based on naturalistic inquiry. This methodology was used to describe parental experiences using their own words and not interpret these experiences. Research participants were recruited from a Level 4 National Association of Epilepsy Center at a Children's Hospital in the Northeast. A purposive sample of twelve parental caregivers participated. Themes that emerged from the interviews included (1) Journey to Diagnosis, Connecting the Dots, (2) Drunken Sailor, Medication Management, (3)Negotiating and Advocacy for Education (4) Provider Challenges, Communication and Parenting and (5) It Takes a Village: Sibling, Family Members and Friends. Nurses play a significant role in education, advocating, and guiding families through the initial diagnosis to dealing with activities of daily living and future planning. This research study serves as a foundation for future intervention studies regarding how best to support parents of children with intractable epilepsy
Thesis (PhD) — Boston College, 2013
Submitted to: Boston College. Connell School of Nursing
Discipline: Nursing
Lalkhen, Nuruneesa. "The quality of life of parents of children with epilepsy." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/53152.
Full textENGLISH ABSTRACT: The focus of the present review is the quality of life (QOL) of parents caring for a child with epilepsy. The review is informed by published books and articles available on the Psychlit and Medline databases. The paper provides an overview of epilepsy and the problems patients, particularly children, are confronted with. The important roles that parents fulfil in their child's life is followed by a discussion of the stress and burden experienced by parents caring for a child with epilepsy. Descriptions and definitions of the construct QOL are followed by reported research findings on the QOL of patients with epilepsy. The importance of the QOL of parents caring for a child with epilepsy is emphasized and this leads to an examination of existing research on the QOL of these parents. Research on the QOL of parents of children with epilepsy is limited despite the important roles parents fulfil in the life of their child with epilepsy and the potentially negative consequences of these additional roles for the child, the parents and the remainder of the family. Identification and an understanding of the dimensions of QOL of parents that are impacted upon by a child's epilepsy may produce improved treatment outcomes and QOL for children diagnosed and living with epilepsy. Recommendations for future research are included in the present review.
AFRIKAANSE OPSOMMING: Die fokus van hierdie oorsig is die lewenskwaliteit van ouers wat 'n epileptiese kind versorg. Die oorsig is gebaseer op gepubliseerde boeke en artikels wat beskikbaar is op Psychlit en Medline databasisse. Die oorsig voorsien 'n omskrywing van epilepsie asook van die probleme wat pasiente, veral kinders, ondervind. Die belangrike rolle wat ouers in hul kinders se lewe speel word bespreek en dit word gevolg deur 'n bespreking van die stres en druk wat ouers wat epileptiese kinders versorg, ondervind. Beskrywings en definisies van die konstruk lewenskwaliteit word aangebied, gevolg deur 'n opgawe van navorsingsbevindinge oor die lewenskwaliteit van epiletiese pasiënte. Die belangrikheid van die lewenskwaliteit van ouers van 'n epileptiese kind word beklemtoon en dit lei tot 'n oorsig van huidige navorsing oor die lewenskwaliteit van hierdie ouers. Ten spyte van die belangrike rolle wat ouers in die lewe van hul epileptiese kind speel en die moontlike negatiewe gevolge van hierdie bykomende rolle vir die kind, die ouers en die ander familielede, is navorsing oor die lewenskwaliteit van ouers met epileptiese kinders beperk. Identifisering van en insig in die faktore wat 'n impak het op die lewenskwaliteit van ouers met 'n epileptiese kind, kan lei tot verbeterde behandelingresultate en hoër lewenskwaliteit vir kinders wat gediagnoseer word en wat met epilepsie saamleef. Aanbevelings vir toekomstige navorsing word ook in hierdie oorsig gemaak.
Papazoglou, Aimilia. "Medical and neuropsychological predictors of adaptive functioning in children with epilepsy." unrestricted, 2009. http://etd.gsu.edu/theses/available/etd-08122009-132658/.
Full textTitle from file title page. Tricia Z. King, committee chair; Robin Morris, Christopher Henrich, Thomas G. Burns, committee members. Description based on contents viewed Sept. 2, 2009. Includes bibliographical references (P. 121-134).
Sillifant, Kate Louise. "Psychiatric morbidity in children with epilepsy : the development and testing of a modified version of the child behavior checklist for use in children with epilepsy." Thesis, University of Leeds, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415602.
Full textClarke, Allison, and n/a. "The impact of epilepsy on the psychosocial functioning of young people." Swinburne University of Technology, 2007. http://adt.lib.swin.edu.au./public/adt-VSWT20080811.093324.
Full textFong, Chung-yan Gardian. "Electro-clinical study and gene mapping of epilepsies." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B24463826.
Full textHarlan, Drewel Elena. "Peer difficulties in children with epilepsy association with medical, neuropsychological, academic, and behavioral factors /." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/4850.
Full textThe entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on March 19, 2009) Vita. Includes bibliographical references.
Hunter, Matthew. "NEUROPROFILES : NEUROdevelopment in PReschool children Of FIfe and Lothian Epilepsy Study." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28870.
Full textPraninskienė, Rūta. "Sleep disorders and melatonin secretion-excretion patterns in children with epilepsy." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20130124_081710-20457.
Full textVaikų miego sutrikimai – dažna problema, dėl kurios tėvai kreipiasi į gydytoją. Jei vaikui būdingi keli miego sutrikimai ir (ar) jis serga kita liga, tai diagnozuoti ir gydyti miego sutrikimus yra sudėtinga. Miego sutrikimams ir epilepsijai būdingas komorbidiškumas. Literatūros duomenimis, vaikams, sergantiems epilepsija, empiriškai skiriama sintetinių melatonino preparatų. Įrodyta, kad jie sutrumpina užmigimo laiką, reguliuoja miego struktūrą, todėl retėja epilepsijos priepuoliai. Tačiau epilepsija sergančių vaikų melatonino sistema dar nebuvo tiriama. Darbo tikslas – išsiaiškinti epilepsija sergančių vaikų dažniausius miego sutrikimus ir kankorėžinės liaukos hormono melatonino, jo metabolito 6-sulfatoksimelatonino (aMT6s) paros cirkadinio profilio ypatumus bei ryšį su epilepsijos formomis, priepuoliais, priepuolių laiku, vartojamais vaistais nuo epilepsijos (VNE) bei kitų fiziologinių rodiklių cirkadiniu ritmu (kūno temperatūros, širdies susitraukimų dažnio, arterinio kraujo spaudimo). Rezultatai parodė, kad epilepsija sergančių vaikų miego sutrikimų skalės (VMSS) rodikliai buvo aukštesni visuose miego sutrikimų pogrupiuose. Dažnesni buvo padidėjusio mieguistumo bei miego ir budrumo ritmo sutrikimai. Kontrolinėje ir sergančių epilepsija vaikų grupėse melatonino apykaita, išreikšta ekskrecijos metabolito aMT6s kiekis kūno svorio vienetui, turėjo neigiamą ryšį su amžiumi ir lytinės brandos stadija. Vaikų, sergančių epilepsija, cirkadinis melatonino sekrecijos ir ekskrecijos... [toliau žr. visą tekstą]
Wood, Stephen James. "Memory dysfunction and focal pathology in children with temporal lobe epilepsy." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300670.
Full textChan, Samantha Yuen-Sum. "The contribution of sleep to cognitive function in children with epilepsy." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/10024776/.
Full textYung, Wing-yan Ada, and 楊穎欣. "Clinical outcome and prognosis of childhood epilepsy (1996-2006)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45153322.
Full textKorman, Brandon M. "Memory Performance in Children with Temporal Lobe Epilepsy: Neocortical vs. Dual Pathologies." Diss., NSUWorks, 2016. https://nsuworks.nova.edu/cps_stuetd/107.
Full textDahllöf, Göran. "Phenytoin-induced gingival overgrowth in epileptic children a clinical, histological and biochemical study /." Stockholm : [Karolinska Institutet], 1986. http://catalog.hathitrust.org/api/volumes/oclc/13674550.html.
Full textDuffy, Lisa. "Testing the Efficacy of the Creating Opportunities for Parent Empowerment (COPE) Intervention During Hospital to Home Transition: Empowering Parents of Children with Epilepsy and Other Neurological Conditions." Thesis, Boston College, 2013. http://hdl.handle.net/2345/3030.
Full textBackground: Parents of children with epilepsy and other neurological conditions live with a feeling of constant uncertainty. The uncertainty associated with caring for a child with epilepsy and other neurological conditions produces stress, which leads to decreased parental belief in caregiving skills, anxiety, and depression, ultimately altering parental functioning resulting in an increase in child behavioral problems. The stress associated with caring for a child with epilepsy and other neurological conditions is unlike caring for children with other chronic conditions. Epilepsy and other neurological conditions are unpredictable and there are often no warning signs prior to an acute event. This unpredictability accompanied with stigma results in social isolation and impacts family functioning. In addition, children with epilepsy have a higher rate of psychological co-morbidities and behavior problems when compared to children with other chronic conditions. This produces an additional burden on the parents and family. Study Design: This randomized controlled trial tested the efficacy of the COPE intervention for parents of children with epilepsy and other neurological conditions. This intervention was administered at three intervals: 1) during hospital admission in writing and by audiotape, MP3 download, or Podcast; 2) three days following hospital discharge by telephone; and 3) four to six weeks after hospital discharge in writing and by audiotape, MP3 download, or Podcast. Results: Forty-six parents of children admitted to the inpatient neuroscience unit at Boston Children's Hospital participated in the study. Several study limitations resulted in an inadequate sample size to obtain the power necessary to reach statistically significant results for a majority of the research questions. A one-between, one-within multivariate analysis of variance (MANOVA) revealed that the main effect of time was significant for differences in state anxiety for both the Usual Care Group and the Intervention Group, F, (1, 20) = 9.86, p = .005, indicating that state anxiety for both groups combined was more pronounced during the hospitalization. A one-between, one-within MANOVA demonstrated that the effect of the interaction between time and group was significant for internalized behavior assessment system score only (p=.037) as the Usual Care Group reported a significant decrease in internalizing behavior scores in their children over time. Conclusions: Findings from this study have significant implications for clinical practice and future research. Parents of children with neurological conditions often struggle to manage a constant feeling of uncertainty in their daily lives. Nurses possess the knowledge and expertise necessary to identify the psychosocial needs of these parents and provide education and support as needed. Future research should focus on designing interventions to meet the needs of these families and develop strategies to help improve the quality of life for both the parent and child living with a neurological condition
Thesis (PhD) — Boston College, 2013
Submitted to: Boston College. Connell School of Nursing
Discipline: Nursing
Bencivenga, Roberto. "A statistical analysis of electroencephalographic spikes in benign Rolandic epilepsy of childhood." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26165.
Full textScience, Faculty of
Statistics, Department of
Graduate
Graveline, Chantal. "Reorganization of sensorimotor functions pre and post hemispherectomy in children with refractory epilepsy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0005/NQ41166.pdf.
Full textRiney, Catherine Josephine. "Improving the detection of focal brain abnormality in children with intractable focal epilepsy." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/17230/.
Full textSarri, Margarita. "Factors predictive of emotional and behavioural difficulties in children with refractory focal epilepsy." Thesis, Royal Holloway, University of London, 2014. http://digirep.rhul.ac.uk/items/e1e081c7-3d68-8a76-2a43-b294e1dd7dad/1/.
Full textGrayson-Collins, Jasmin. "Accelerated long-term forgetting and academic achievement in children with idiopathic generalised epilepsy." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/12071.
Full textJoplin, Samantha Kate. "Accelerated Long-term Forgetting in Children with Epilepsy: An Investigation of the Temporal Trajectory and Contribution of Executive Skills." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29891.
Full text方頌恩 and Chung-yan Gardian Fong. "Electro-clinical study and gene mapping of epilepsies." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31981781.
Full textKija, Edward Nkingwa. "Bone metabolism abnormalities in children with epilepsy at Red Cross War Memorial Children's Hospital, Cape Town, South Africa." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/27013.
Full textMankinen, K. (Katariina). "Neuropsychological performance and functional MRI findings in children with non-lesional temporal lobe epilepsy." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526203546.
Full textTiivistelmä Tutkimuksen tarkoituksena oli selvittää onko lapsilla, jotka sairastavat tuntemattomasta syystä aiheutuvaa ohimolohkoepilepsiaa, neuropsykologisia ongelmia ja aiheuttavatko mahdolliset ongelmat aivojen toiminnallisessa magneettikuvauksessa nähtäviä muutoksia. Tähän väestöpohjaiseen tutkimukseen otettiin 21 tuntemattomasta syystä ohimolohkoepilepsiaa sairastavaa normaaliälyistä 8-15-vuotiaista lasta ja verrattiin heitä 21 terveeseen, ikä- ja sukupuolivakioituun kontrollihenkilöön. Kaikille tutkimukseen osallistuneille tehtiin neuropsykologinen tutkimus, kliininen tutkimus, aivosähkökäyrä sekä rakenteellinen ja toiminnallinen aivojen magneettikuvaus. Toiminnallisessa magneettikuvauksessa käytettiin veren happipitoisuudesta riippuvaista (engl. blood oxygenation level-dependent) kontrastia kuvantamaan levossa aivojen paikallista homogeniteettia (engl. regional homogeneity) ja toiminnallista kytkennällisyyttä (engl. functional connectivity) sekä kognitiivisten tehtävien herättämiä aktivaatio-vasteita. Tuntemattomasta syystä ohimolohkoepilepsiaa sairastavien lasten neuropsykologinen suoriutuminen oli keskimäärin hyvää, vaikkakin tytöillä oli nähtävillä tilastollisesti merkitseviä ongelmia useissa eri testeissä. Ongelmat eivät rajoittuneet pelkästään klassisiin ohimolohkoalueen muistitoimintoihin, vaan niitä havaittiin myös otsa- ja päälakilohkojen toimintoja edellyttävissä testeissä. Varhainen sairastumisikä ja epilepsian kesto heikensivät suoriutumista tilastollisesti merkitsevästi osatesteissä, joissa tarvittiin näönvaraisen hahmottamisen taitoja, psykomotorista nopeutta ja työmuistia. Ohimolohkoepilepsiaa sairastavien ja terveiden kontrollien aivoissa löydettiin toiminnallisia eroja kaikilla toiminnallisen magneettikuvauksen menetelmillä. Eroja ei todettu ainoastaan ohimolohkoissa, vaan niitä löytyi myös otsa- ja päälakilohkoon sekä tyvitumakealueelle ylettyvissä laaja-alaisissa hermoverkostoissa. Epilepsiapotilailla erojen paikantuminen riippui kohtaustenvälisestä aivosähkökäyrälöydöksestä. Neuropsykologisen suoriutumisen tulokset tukevat toiminnallisen magneettikuvauksen löydöksiä kuvastaen temporaaliepilepsian olevan laaja-alainen hermoverkostojen häiriö eikä pelkästään tietyn aivoalueen toiminnan häiriö. Tämä tulee huomioida arvioitaessa ohimolohkoepilepsiaa sairastavien lasten oppimiskykyä jo epilepsian alkuvaiheessa
Pressler, Ronit. "Effects of interictal discharges on cognition and behaviour in children with well-controlled epilepsy." Thesis, King's College London (University of London), 2006. https://kclpure.kcl.ac.uk/portal/en/theses/effects-of-interictal-discharges-on-cognition-and-behaviour-in-children-with-wellcontrolled-epilepsy(f7e23f78-3a00-49eb-a594-959f0bcfe4e0).html.
Full textStrekas, Amy Marie. "Listener quality judgments of narratives produced by children with and without localization-related epilepsy." College Park, Md.: University of Maryland, 2008. http://hdl.handle.net/1903/8610.
Full textThesis research directed by: Dept. of Hearing and Speech Sciences. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
Glidden, Gina. "Intensity of participation among children with epilepsy: an exploratory factor analysis of child components." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119358.
Full textBien que la participation ait été étudiée comme objectif de résultat chez des enfants atteints de paralysie cérébrale ainsi que d'autres conditions chroniques de la santé, très peu est connu au sujet de l'expérience de participation des enfants atteints d'épilepsie. L'objectif de ce mémoire est de déterminer les composantes principales de variables issues de théories liées à l'intensité de la participation des enfants et des adolescents atteints d'épilepsie afin de susciter une discussion qui approfondira notre compréhension de la participation de ce groupe. Seize variables ont été identifiées. Cette étude utilise une base de données comprenant n=506 enfants atteint d'épilepsie afin d'effectuer une analyse exploratoire de facteurs des variables pertinentes liées à l'enfant issues de l'étude QUALITÉ, une étude longitudinale à travers le Canada sur les objectifs de résultat d'enfants atteints d'épilepsie. Quatre composantes principales ont été extraites des résultats, totalisant 63.41% de la variance. La composante Comportements qui facilitent les interactions avec autrui est constituée de quatre variables d'habiletés sociales chez l'enfant et représente 32,04% de la variance. La composante Comportements qui restreignent les interactions avec les autres est constituée de trois variables sur les comportements extériorisés et représente 12.05% de la variance. La composante Cycle de réaction anticipée de l'enfant à des stimuli bouleversants est constituée de variables liées à la soumission, à la victimisation et à l'anxiété et représente 9.41% de la variance. La composante L'être social de l'enfant comprend trois variables liées au soutien social et à la perception de soi et représente 8.40% de la variance. Une étude plus approfondie est nécessaire afin d'examiner la relation et l'impact de ces composantes sur la participation des enfants et des adolescents atteints d'épilepsie.
Raffaele, Martin. "An exploration of the psychosocial effects that school-age children with Child Absence Epilepsy (CAE) experience when their condition is misdiagnosed as Attention-Deficity/Hyperactivity Disorder (ADHD)." Connect to full text, 2009. http://hdl.handle.net/2123/5390.
Full textTitle from title screen (viewed 21st September, 2009) Submitted in fulfilment of the requirements for the degree of Master of Philosophy to the Faculty of Education and Social Work, University of Sydney. Includes bibliographical references. Also available in print form.
Zanni, Karina Piccin. "Crenças e atitudes sobre epilepsia infantil adaptação transcultural do instrumento the epilepsy beliefs and attitudes scale." Universidade Federal de São Carlos, 2010. https://repositorio.ufscar.br/handle/ufscar/3054.
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The childhood epilepsy is a chronic neurological disorder, most common in childhood, associated with profound psychosocial limitations in daily life in epileptic children. These limitations may be related to the characteristics of the disease as the age of onset, severity and type of epilepsy and the lack of information that is still as one of the factors that most contribute to the stigma and discrimination. The association between the variables of epilepsy and the presence of wrong beliefs can lead to decreased academic performance and the presence of problems of psychosocial adjustment. This study aimed to identify and compare beliefs about epilepsy in parents and teachers of epileptic children and to verify the insertion of these children in regular schools and special. To achieve the purposes of this research were carried out two studies: Study 1 aimed to complete the process of transcultural adaptation of the instrument The Epilepsy Beliefs and Attitudes Scale (EBAS) - Adult Version and submit a version in Portuguese for use in Brazil and Study 2 aimed to investigate the number of epileptic children who attended regular schools and special cities involved in the research, compare the school attendance among children with epilepsy and children with typical development or other chronic diseases, identifying variables of epilepsy related to type of school that children attend, in addition to compare the beliefs of parents and teachers of children with epilepsy. Participated in Study 1, 17 toplevel professionals who have made the conceptual, of items, operational and semantics equivalence, and 545 adults who answered the Brazilian version of EBAS - Adult Version whose answers were considered to analyze the psychometric characteristics of the instrument including Alpha Cronbach's, factor analysis and test-retest reliability. The results showed that the concepts learned by the instrument were considered relevant to our culture and its items as appropriate to their ability to represent these concepts in the target population, and provide good semantic equivalence between the final version in Portuguese and original. The index of consistency for the overall scale was 0.89, the factorial analysis confirmed the original structure with three subscales (neurological, metaphysics and environmental/psychophysics) and test-retest showed that the instrument is reliable. Were participants of Study 2, 205 people, with 91 children aged between 7 and 14 years, 56 parents and 56 teachers, and 2 teenagers involved with the pre-test. Seven instruments were used to collect data: 1) Data sheets of identification and characterization of the family, the child and the teacher; 2) Brazil Criterion of Economic Classification 2008; 3) Classification of Engel; 4) Data sheet to record the frequency the school year; 5) Brazilian Version of EBAS - Adult Version. The data obtained by means of the instruments were analyzed descriptively and compared, using the Statistic Software Minitab - Version 12.1, using the Student t test, Mann-Whitney, chi-square and logistic regression. The results showed that children from special schools when compared to children from regular schools had severe disease and higher frequency of crises, beginning early and duration of epilepsy, and consume a greater number of medicines and make school attendance lower. Logistic regression analysis showed that age of onset and severity of illness, number of drugs used and the presence of comorbidities were related to the type of school that children attend. No differences were found statistically significant between the beliefs of parents and teachers, though both have made more inappropriate beliefs and attitudes than adequate to the epileptic child. It is concluded that this study helped to identify issues related to the processes of inclusion of children with epilepsy, identifying difficulties and limitations that interfere with the schooling of these students as well as the choice of attending school.
A epilepsia infantil é uma afecção neurológica crônica, muito comum na infância, associada a limitações psicossociais profundas na vida diária da criança epiléptica. Estas limitações podem estar ligadas às características da própria doença como a idade de início, a gravidade e o tipo da epilepsia e à falta de informação que ainda se constitui como um dos fatores que mais contribui para o estigma e a discriminação. A associação entre as variáveis da epilepsia e a presença de crenças inadequadas pode levar a diminuição do rendimento acadêmico bem como a presença de problemas de ajustamento psicossocial. Dessa forma, o presente estudo teve como objetivos identificar e comparar as crenças sobre epilepsia de pais e professores de crianças epilépticas e verificar a inserção dessas crianças em escolas regulares e especiais. Para atingir os propósitos dessa pesquisa foram realizados dois estudos: o Estudo 1 que teve como objetivo realizar o processo de adaptação transcultural do instrumento The Epilepsy Beliefs and Attitudes Scale (EBAS) Adult Version e apresentar uma versão em português para uso no Brasil e o Estudo 2 visando investigar o número de crianças epilépticas que freqüentavam escolas regulares e especiais nos municípios envolvidos na pesquisa; comparar a freqüência escolar entre crianças com epilepsia e crianças com desenvolvimento típico ou outras doenças crônicas; identificar variáveis da epilepsia ligadas ao tipo de escola que as crianças freqüentavam e comparar as crenças de pais e professores das crianças com epilepsia. Participaram do Estudo 1, 17 profissionais de nível superior que realizaram a equivalência conceitual, de itens, semântica e operacional, além de 545 adultos que responderam a versão brasileira da EBAS Adult Version cujas respostas foram consideradas para a análise das características psicométricas do instrumento incluindo Alfa de Cronbach, análise fatorial e confiabilidade teste-reteste. Os resultados mostraram que os conceitos apreendidos pelo instrumento foram considerados pertinentes à nossa cultura e seus itens adequados quanto à sua capacidade de representar tais conceitos na população-alvo, além de apresentar boa equivalência semântica entre a versão final em português e o original. O índice de consistência interna para a escala geral foi de 0,89, a análise fatorial confirmou a estrutura original com três subescalas (neurológica, metafísica e ambiental/psicofísica) e o teste-reteste mostrou que o instrumento é confiável. Foram participantes do Estudo 2, 205 pessoas, sendo 91 crianças com idade entre 7 e 14 anos, 56 pais e 56 professores, além de 2 adolescentes envolvidas com o pré-teste. Utilizaram-se para a coleta de dados sete instrumentos: 1) Formulários de identificação e caracterização da família, da criança e do professor; 2) Critério de Classificação Econômica Brasil 2008; 3) Classificação de Engel; 4) Formulário para registro de freqüência às aulas; 5) Versão brasileira da EBAS Adult Version. Os dados obtidos por meio dos instrumentos foram analisados descritiva e comparativamente, utilizando-se o Software Estatístico Minitab Versão 12.1, por meio dos testes t de Student, Mann-Whitney, qui-quadrado, além de regressão logística. Os resultados mostraram que as crianças das escolas especiais quando comparadas às crianças das escolas regulares apresentavam gravidade da doença e freqüência de crises mais elevadas, a epilepsia iniciava-se mais cedo e portanto sua duração era mais longa, além de consumirem número maior de medicamentos e apresentarem freqüência escolar menor. A análise de regressão logística mostrou que as variáveis idade de início e gravidade da epilepsia, número de medicamentos utilizados e presença de comorbidades estavam relacionadas ao tipo de escola que as crianças deste estudo freqüentavam. Não foram detectadas diferenças estaticamente significativas entre as crenças de pais e professores, embora ambos tenham apresentados mais crenças e atitudes inadequadas do que adequadas perante a epilepsia infantil. Conclui-se que esta pesquisa permitiu a disponibilização de um instrumento voltado a detecção de crenças e atitudes sobre epilepsia infantil e contribuiu para a identificação de questões ligadas ao processo de escolarização de crianças com epilepsia.
Casali, Raquel Leme 1984. "Potenciais evocados auditivos em crianças com epilepsia benigna da infância com espículas centrotemporais e epilepsia de lobo temporal." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310929.
Full textTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
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Resumo: As descargas cerebrais anormais presentes na epilepsia benigna da infância com espículas centrotemporais (EBICT) e na epilepsia de lobo temporal (ELT) localizam-se em regiões próximas às áreas responsáveis pelo processamento auditivo e linguístico. Esse estudo teve como objetivo analisar os resultados do potencial evocado auditivo de tronco encefálico (PEATE) e do P300 em crianças com EBICT e ELT, a fim de avaliar se a atividade epiléptica nas regiões centrotemporais e temporais pode prejudicar a integridade e a fisiologia das estruturas do sistema auditivo. Tratou-se de estudo de corte transversal comparativo e prospectivo. O Grupo I (GI) foi composto por 13 crianças com diagnóstico de EBICT, GII por 07 crianças com ELT e grupo controle (GIII) por 16 crianças sem epilepsia, queixas auditivas e/ou escolares. Após avaliação neurológica e audiológica, foram aplicados os testes eletrofisiológicos PEATE e P300. Os valores de latência absoluta das ondas I, III e V, interpicos I-III, III-V e I-V, bem como a latência e amplitude da onda P300 foram comparados entre os grupos. Em relação ao PEATE, os pacientes com EBICT apresentaram diferenças estatisticamente significativas para as latências absolutas das ondas I e V, sendo esses valores prolongados em comparação aos observados no grupo controle. Os pacientes com ELT apresentaram diferenças estatisticamente significativas para as latências absolutas das ondas I e III, as quais estavam aumentadas em comparação aos observados no grupo controle. ... Observação: O resumo, na íntegra, poderá ser visualizado no texto completo da tese digital
Abstract: The abnormal brain discharges present in benign childhood epilepsy with centrotemporal spikes (BECTS) and temporal lobe epilepsy (TLE) are located in close proximity to areas responsible for auditory and language processing. This study aimed to analyze the results of auditory brainstem responses (ABR) and P300 in children with BECTS and TLE in order to assess whether the epileptic activity in the centro-temporal regions may compromise the integrity and physiology of the structures of auditory system. This was a prospective, comparative and cross-sectional study. Group I (GI) consisted of 13 children diagnosed with BCECTS, GII 07 children with TLE and control group (GIII) 16 children without epilepsy, hearing nor academic complaints. After neurological and audiological evaluation, electrophysiological testing ABR and P300 were applied. The values of waves I, III and V absolute latencies, and I-III, III-V and IV interpeaks, as well as P300 latency and amplitude were compared between groups. Regarding ABR, patients with BECTS showed statistically significant differences for waves I and V absolute latencies, and these values were prolonged compared to those observed in control group. TLE patients showed statistically significant differences for waves I and III absolute latencies, which were increased compared to those observed in GIII. ... Note: The complete abstract is available with the full electronic digital thesis or dissertation
Doutorado
Saude da Criança e do Adolescente
Doutora em Ciências
Longato, Carolina Ruiz. "Avaliação neuropsicológica e afetiva de crianças e adolescentes com epilepsia." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/59/59137/tde-13052015-151915/.
Full textThe study of the emotional functioning characteristics of children with epilepsy is an important area that can provide an understanding of the impact of chronic clinical picture of the emotional development and social kids. The prospect of linking empirical evidence of cognitive and emotional approach, expanding the strategies commonly used in neuropsychological assessment procedures may allow more comprehensive interpretations of the picture. This study aimed to characterize the cognitive and emotional functioning of children and adolescents with epilepsy from specific instruments of psychological assessment, highlighting resources and possible difficulties to adjust to the context of life. We evaluated two clinical groups of children and adolescents from seven to 16 years, regularly seen at the Epilepsy Surgery Center (CIREP), Hospital das Clínicas of the Ribeirão Preto Medical School, University of São Paulo, as follows: Group 1 (preoperative, n = 17): patients with epilepsy hospitalized in CIREP; Group 2 (post-operatory, n = 18): patients who underwent epilepsy surgery, with control of seizures and attending the outpatient clinic of CIREP. He composed a third group (comparison group, n = 31) with volunteers from public schools, similar in age and sex to the clinical groups. The instruments used were: Strengths and Difficulties Questionnaire (SDQ), Wechsler Intelligence Scale for Children (WISC-III), Corsi Blocks test (TBC) and Test of Pfisters Color Pyramid. Descriptive and inferential analyzes were performed in order to allow neuropsychological characterization and emotional functioning of children and adolescents. Finally, we performed the general profile of results of the clinical group (n = 35) in each instrument, and compared to its normative data. The evidence obtained by the SDQ point out that epilepsy patients groups have more problems with emotional problems, hyperactivity, problems with colleagues and school learning than children and adolescents in the comparison group. Through the cognitive tests (III and WlSCCorsi test), it was found that the clinical cases showed a cognitive and spacial memory performance below the comparison group. The projective personality assessment method (Pfister test), on the other hand, showed indications of inhibition at lower affective clinical cases, compared with the nonpatients children and adolescents, although in general it has been found that the emotional experiences are preserved in all cases. Compared to normative data, the clinical group had lower scores on IQ scores and in all evaluated subtests (WISC-III), lower average scores in front of the Corsi Test (forward and reverse version), plus the following findings the Pfister test: medium percentages of brown and gray colors and significantly higher stimulation syndrome, medium percentages of white and colorless syndrome significantly below the standard average, with preference for the realization of punched carpets. The set of findings suggests lower cognitive function and signs of instability in the control of emotions in the group with epilepsy, confirming the need for specific interventions with these children and adolescents throughout their development, in order to encourage appropriate use of their potential.
Greechan, Martha. "Illness meaning and perceived support of parents of children with severe myoclonic epilepsy of infancy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0002/MQ36451.pdf.
Full textDahlin, Maria. "Pharmacodynamics of low-dose clonazepam in children with epilepsy or spasticity : neurophysiological and clinical studies /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4862-3/.
Full textBurton, Kathryn Joanna. "Prevalence, risk factors, co-morbidity and perception of epilepsy in children from Hai District, Tanzania." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610294.
Full textElliott, Jesse. "Medical Cannabis for the Treatment of Drug-Resistant Epilepsy in Children: A Health Technology Assessment." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40474.
Full textVollmer, B. "The neural basis of epilepsy and cognitive impairment in children born preterm : a neuroimaging study." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1446148/.
Full textJoshi, S. M., K. Gali, L. Radecki, P. R. Sachdeva, T. Calabrese, A. Shah, S. Huenke, L. Brown, E. Kimball, and David Wood. "Integrating Quality Improvement into the ECHO Model to Improve Care for Children and Youth with Epilepsy." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7671.
Full textHarrison, Jordan. "Longitudinal Health-Related Quality of Life in Children with Newly-Diagnosed Epilepsy: Identifying Predictors and Assessing Meaningful Change over Time." Xavier University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=xavier1510307341014498.
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