Relevant bibliographies by topics / Epilepsy in children

Academic literature on the topic 'Epilepsy in children'

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Published: 4 June 2021
Last updated: 1 August 2024

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Journal articles on the topic "Epilepsy in children"

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Budiman, Marshen, Praevilia M. Salendu, and Johnny L. Rompis. "Pengaruh Riwayat Kejang Demam terhadap Kejadian Epilepsi pada Anak." e-CliniC 11, no. 1 (October 10, 2022): 19. http://dx.doi.org/10.35790/ecl.v11i1.37740.

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Abstract: Epilepsy could cause various kinds of problems including learning difficulties, growth and development disorders, and poor quality of life of children in the future. There are several risk factors of febrile seizures that coud affect the occurrence of epilepsy inter alia abnormalities of the nervous system or there is a clear development of nervous system abnormalities before the seizure, complex febrile seizures, history of epilepsy in parents or siblings, as well as simple febrile seizures repeating four or more episodes in one year. Each of these risk factors increases the likeli-hood of epilepsy, and the combination of these risk factors increases the incidence of epilepsy. This study aimed to determine the effect of a history of febrile seizures on the incidence of epilepsy in children. This was a literature review study using three databases namely Pubmed, ClinicalKey, and Google Scholar. The keywords used were febrile seizure AND epilepsy AND children. Selection with inclusion and exclusion criteria obtained 10 literatures. The results showed that from 10 literatures reviewed, history of febrile seizures was the most common risk factor that influenced the developing of epilepsy in later life. In conclusion, history of febrile seizures is the most common risk factor for developing epilepsy in children later in life. The percentage of children with history of febrile seizure that develop to epilepsy is 3.3% - 73.8%.Keywords: febrile seizures; epilepsy; children Abstrak: Epilepsi dapat menyebabkan berbagai macam permasalahan berupa kesulitan dalam belajar, gangguan pertumbuhan dan perkembangan, serta kualitas hidup yang kurang pada anak di masa depan. Terdapat beberapa faktor risiko kejang demam yang berperan terhadap terjadinya epilepsi, di antaranya: kelainan pada sistem saraf atau adanya perkembangan kelainan yang jelas sebelum kejang, kejang demam kompleks, riwayat epilepsi pada orang tua atau suadara kandung, dan kejang demam sederhana yang berulang empat episode atau lebih dalam satu tahun. Masing-masing faktor risiko tersebut meningkatkan kemungkinan kejadian epilepsi dan kombinasi faktor risiko tersebut akan meningkatkan kejadian epilepsi. Penelitian ini bertujuan untuk mengetahui pengaruh riwayat kejang demam terhadap kejadian epilepsi pada anak. Penelitian ini berbentuk literature review, menggunakan tiga database yaitu Pubmed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan yaitu febrile seizure AND epilepsy AND children. Hasil seleksi dengan kriteria inklusi dan eksklusi mendapatkan 10 literatur. Hasil penelitian menunjukkan bahwa dari sepuluh jurnal yang di-review, didapatkan riwayat kejang demam menjadi salah satu faktor risiko yang memiliki pengaruh untuk berkembang menjadi epilepsi di kemudian hari. Simpulan penelitian ini ialah riwayat kejang demam merupakan faktor risiko terbanyak untuk berkembang menjadi epilepsi pada anak di kemudian hari. Persentase anak dengan riwayat kejang demam yang berkembang menjadi epilepsi berkisar antara 3,3% - 73,8%.Kata kunci: kejang demam; epilepsi; anak
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Budiman, Marshen, Praevilia M. Salendu, and Johnny L. Rompis. "Pengaruh Riwayat Kejang Demam terhadap Kejadian Epilepsi pada Anak." e-CliniC 11, no. 1 (October 10, 2022): 19–26. http://dx.doi.org/10.35790/ecl.v11i1.44268.

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Abstract: Epilepsy could cause various kinds of problems including learning difficulties, growth and development disorders, and poor quality of life of children in the future. There are several risk factors of febrile seizures that coud affect the occurrence of epilepsy inter alia abnormalities of the nervous system or there is a clear development of nervous system abnormalities before the seizure, complex febrile seizures, history of epilepsy in parents or siblings, as well as simple febrile seizures repeating four or more episodes in one year. Each of these risk factors increases the likeli-hood of epilepsy, and the combination of these risk factors increases the incidence of epilepsy. This study aimed to determine the effect of a history of febrile seizures on the incidence of epilepsy in children. This was a literature review study using three databases namely Pubmed, ClinicalKey, and Google Scholar. The keywords used were febrile seizure AND epilepsy AND children. Selection with inclusion and exclusion criteria obtained 10 literatures. The results showed that from 10 literatures reviewed, history of febrile seizures was the most common risk factor that influenced the developing of epilepsy in later life. In conclusion, history of febrile seizures is the most common risk factor for developing epilepsy in children later in life. The percentage of children with history of febrile seizure that develop to epilepsy is 3.3% - 73.8%. Keywords: febrile seizures; epilepsy; children Abstrak: Epilepsi dapat menyebabkan berbagai macam permasalahan berupa kesulitan dalam belajar, gangguan pertumbuhan dan perkembangan, serta kualitas hidup yang kurang pada anak di masa depan. Terdapat beberapa faktor risiko kejang demam yang berperan terhadap terjadinya epilepsi, di antaranya: kelainan pada sistem saraf atau adanya perkembangan kelainan yang jelas sebelum kejang, kejang demam kompleks, riwayat epilepsi pada orang tua atau suadara kandung, dan kejang demam sederhana yang berulang empat episode atau lebih dalam satu tahun. Masing-masing faktor risiko tersebut meningkatkan kemungkinan kejadian epilepsi dan kombinasi faktor risiko tersebut akan meningkatkan kejadian epilepsi. Penelitian ini bertujuan untuk mengetahui pengaruh riwayat kejang demam terhadap kejadian epilepsi pada anak. Penelitian ini berbentuk literature review, menggunakan tiga database yaitu Pubmed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan yaitu febrile seizure AND epilepsy AND children. Hasil seleksi dengan kriteria inklusi dan eksklusi mendapatkan 10 literatur. Hasil penelitian menunjukkan bahwa dari sepuluh jurnal yang di-review, didapatkan riwayat kejang demam menjadi salah satu faktor risiko yang memiliki pengaruh untuk berkembang menjadi epilepsi di kemudian hari. Simpulan penelitian ini ialah riwayat kejang demam merupakan faktor risiko terbanyak untuk berkembang menjadi epilepsi pada anak di kemudian hari. Persentase anak dengan riwayat kejang demam yang berkembang menjadi epilepsi berkisar antara 3,3% - 73,8%. Kata kunci: kejang demam; epilepsi; anak
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Suwarba, I. Gusti Ngurah Made, and Ni Wayan Kurnia Wati. "Fungsi Kognitif Anak Dengan Epilepsi Umum." Buletin Penelitian Sistem Kesehatan 25, no. 1 (May 31, 2022): 12–18. http://dx.doi.org/10.22435/hsr.v25i1.4491.

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Children with epilepsy may experience cognitive impairment due to the effects of structural lesions or seizure activity. This study aims to determine the cognitive function of children with general epilepsy. This study was a cross-sectional design that included children aged 6 to 68 months with general epilepsy in the polyclinic and pediatric ward of Sanglah Hospital Denpasar from September 2013 to January 2015. All children who participated in this study were subjected to a Mullen scale examination. Statistical analysis was performed using Chi-square test and multivariate analysis with logistic regression. In 93 children with general epilepsy, there was a significant correlation between the level of cognitive function and seizure frequency >10 times with an odds ratio 6.067 (95% CI 2.002-18.388, p value 0.001) and seizure duration ≥15 minutes with an odds ratio 6.006 (95% CI 1,817-20,246, p value 0.003). In this study, it can be concluded that seizure frequency >10 times and seizure duration ≥15 minutes in children with general epilepsy have a positive relationship of 6 times with the abnormal cognitive function. Further studies are needed to determine cognitive development of children with general epilepsy. Abstrak Anak dengan epilepsi dapat mengalami gangguan kognitif berkaitan dengan efek dari lesi struktural maupun aktivitas kejang. Penelitian ini ditujukan untuk mengetahui fungsi kognitif anak dengan epilepsi umum. Penelitian ini merupakan penelitian dengan desain potong lintang yang mengikutsertakan anak usia 6 sampai 68 bulan dengan epilepsi umum di poliklinik dan ruang perawatan anak RSUP Sanglah Denpasar pada bulan September 2013 hingga Januari 2015. Semua anak yang ikut serta dalam penelitian dilakukan pemeriksaan skala Mullen. Analisis statistik dilakukan dengan uji kai kuadrat dan analisis multivariat dengan regresi logistik. Pada 93 anak dengan epilepsi umum, didapatkan hubungan yang signifikan antara fungsi kognitif dengan frekuensi kejang >10 kali dengan rasio odds 6,067 (nilai p=0,001, 95% CI 2,002-18,388) dan lama kejang ≥15 menit dengan rasio odds 6,006 (nilai p=0,003, 95% CI 1,817-20,246). Pada penelitian ini dapat disimpulkan bahwa frekuensi kejang >10 kali dan lama kejang ≥15 menit pada anak dengan epilepsi umum memiliki hubungan yang positif sebesar 6 kali terhadap fungsi kognitif abnormal. Penelitian lanjutan perlu dilakukan untuk mengetahui perkembangan fungsi kognitif anak dengan epilepsi umum.
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Upadhyay, Aishvarya, S. K. Upadhyay, O. P. Mishra, and Rajniti Prasad. "Cognitive Dysfunctions in Children with Epilepsy." Pediatric Education and Research 4, no. 3 (2016): 151–54. http://dx.doi.org/10.21088/per.2321.1644.4316.3.

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Sari, Novi Komala, Nina Herlina, and Aswan Jhonet. "HUBUNGAN RIWAYAT KEJANG DEMAM DENGAN KEJADIAN EPILEPSI PADA ANAK ≤ 5 TAHUN DI RSUD Dr. H. ABDUL MOELOEK PROVINSI LAMPUNG TAHUN 2018-2019." Jurnal Kebidanan Malahayati 7, no. 3 (July 31, 2021): 453–58. http://dx.doi.org/10.33024/jkm.v7i3.4203.

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Background : Epilepsy is a neurological disorder which often found in the world and has the highest incidence in children. The most common risk factor of epilepsy is febrile seizure. Febrile seizure refer to a seizure following by high-fever (>38°C) that often found in the age between 6 month – 5 years old. Objective : This study aim to acknowledge the relation between the febrile sizure history and the incidence of epilepsy found in the children of ≤ 5 years old in RSUD Dr. H. Abdul Moeloek Lampung Province 2018-2019. Methods: This study used an analytic research design with cross sectional approach. The population being used are all pediatric patients in the age of ≤ 5 years which diagnosed with epilepsy in RSUD Dr. H. Abdul Moeloek Lampung Province. Further, the sample being used in this research are 42 people which obtained from total sampling technique. While the statistic test being used is Chi square test. Results :Tthis study is show that 31 children (73.8%) had a febrile seizure history, and 11 children (26.2%) had not a febrile seizure history. Further, this study found that 8 children (19.0%) had a partial awakening epilepsy, and 34 children (81.0%) had a general awakening epilepsy. The result of chi square examination which is (p value 0.032) showed that there is a relation between the febrile seizure history and the incidence of epilepsy found in children at age of ≤ 5 yearch in RSUD Dr. H. Abdul Moeloek Provinsi Lampung in the year of 2018-2019. Conclusion : There is a relation between febrile seizure history and the incidence of epilepsy found in child.Suggestion : It is recommended to be able to pay attention, add insight about febrile seizures and epilepsy, so that mothers don’t panic and know how to overcome them. Keywords : Febrile Seizure, Epilepsy, Child ABSTRAK Latar Belakang : Epilepsi merupakan kelainan neurologis yang sering ditemui di dunia dan insidensinya terbanyak pada masa anak-anak. Faktor risiko epilepsi yang tersering adalah kejang demam. Kejang demam mengacu pada kejang yang berhubungan dengan demam tingkat tinggi (> 38°C) yang sering terjadi pada usia 6 bulan – 5 tahun.Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan riwayat kejang demam dengan kejadian epilepsi pada anak ≤ 5 tahun di RSUD Dr. H. Abdul Moeloek Provinsi Lampung 2018-2019. Metode Penelitian : Penelitian ini menggunakan desain penelitian analitik dengan pendekatan cross sectional. Populasi yang digunakan adalah semua pasien anak usia ≤ 5 tahun yang didiagnosis epilepsi di RSUD Dr. H. Abdul Moeloek Provinsi Lampung. Sampel dalam penelitian ini berjumlah 42 orang yang diambil dengan teknik total sampling. Uji statistik yang digunakan adalah uji Chi Square.Hasil Penelitian : Hasil penelitian ini menunjukkan sebanyak 31 anak (73.8%) memiliki riwayat kejang demam, serta 11 anak (26.2%) tidak memiliki riwayat kejang demam. Dan didapatkan sebanyak 8 anak (19.0%) memiliki epilepsi bangkitan parsial, serta 34 anak (81.0%) memiliki epilepsi bangkitan umum. Hasil uji Chi Square yaitu (p value 0.032) terdapat hubungan anatara riwayat kejang demam dengan kejadian epilepsi pada anak ≤ 5 tahun di RSUD Dr. H. Abdul Moeloek Provinsi Lampung Tahun 2018-2019.Kesimpulan : Terdapat hubungan antara riwayat kejang demam dengan kejadian epilepsi pada anak.Saran : Disarankan untuk dapat memperhatikan, menambah wawasan tentang kejang demam dan epilepsi, sehingga ibu tidak panik dan mengetahui cara penanggulangannya. Kata Kunci : Kejang Demam, Epilepsi, Anak.
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Ramadhan, Muhammad Fitra, Prastiya Indra Gunawa, and Muhammad Arifin Parenrengi. "Faktor-Faktor Risiko Pasien Epilepsi Intraktabel pada Anak." Malahayati Nursing Journal 4, no. 12 (December 1, 2022): 3321–34. http://dx.doi.org/10.33024/mnj.v4i12.7518.

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ABSTRACT Approximately 10.5 million children are diagnosed with active epilepsy worldwide, accounting for 25% of the world's population with epilepsy. Among 1 in 3 people who are diagnosed with epilepsy will develop intractable epilepsy, this means that regular and adequate treatment for 18 months does not show a decrease in the frequency and duration of seizures or has taken 2 anti-epileptic drugs but has not yet had an effect. The aim of this study was to analyze the risk factors that can cause intractable epilepsy in pediatric patients. This study used a retrospective observational research design with a systematic review approach, where all variable data were collected from previous studies. The collection of research data is collected from previous research data in the form of research journals collected from the scholar.google.co.id, NCBI, and science direct databases. The article search method uses the characteristics of PICO (Population, Intervention, Comparison, Outcome), then the data in the form of articles that have been collected are managed using the Preffered Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method. Based on 9 articles that have been reviewed, it is found that there are no studies that include age as a risk factor for intractable epilepsy. Odds ratios for each risk factor varied, but the most studied risk factors in the study included in this study were developmental disorders (8/9), MRI / CT Scan (6/9), and status epilepticus (5/9). 9). From the results of this systematic review, the factors that most influence intractable epilepsy in children are developmental disorders with the highest odds ratio of 37.1 obtained in the study of Wirell et al. Gender factors, duration of seizure, family history of epilepsy, and history of febrile seizures did not significantly influence intactable epilepsy. In conclusion, this study found that the factors that most influence intractable epilepsy in children are developmental disorders and status epilepticus. Keywords: Risk Factors, Intractable Epilepsy, Children ABSTRAK Di seluruh dunia, sekitar 10,5 juta anak didiagnosis dengan epilepsi aktif, sebesar 25% dari populasi dunia dengan pengidap epilepsi. Diantara 1 dari 3 orang yang terdiagnosis epilepsi akan dapat berkembang menjadi epilepsi intraktabel, hal ini dapat diartikan bahwa pengobatan yang dilakukan selama 18 bulan secara teratur dan adekuat tidak menunjukkan penurunan frekuensi dan durasi kejang atau sudah mengonsumsi 2 obat anti epilepsi namun belum juga memberikan efek. Tujuan studi ini adalah untuk menganalisis faktor resiko yang dapat menyebabkan epilepsi intraktabel pada pasien anak. Penelitian ini menggunakan desain penelitian observasional retrospektif dengan pendekatan systematic review, dimana semua data variable dikumpulkan dari penelitian yang telah dilakukan sebelumnya. Pengumpulan data penelitian ini dikumpulkan dari data penelitian sebelumnya dalam bentuk jurnal penelitian yang dikumpulkan dari database scholar.google.co.id, NCBI, dan science direct. Metode pencarian artikel menggunakan karakteristik PICO (Population, Intervention, Comparison, Outcome) yang lalu data berupa artikel yang telah terkumpul dikelola dengan menggunakan metode Preffered Reporting Items for Systematic Review and Meta-Analysis (PRISMA). Berdasarkan 9 artikel yang telah dikaji, didapatkan bahwa tidak ada studi yang memasukkan faktor usia dalam sebagai faktor risiko epilepsi intraktabel. Odds ratio untuk masing-masing faktor risiko bervariasi, namun faktor risiko yang diteliti paling banyak pada studi yang diinklusi di penelitian ini adalah gangguan tumbuh kembang (8/9), MRI/CT Scan (6/9), dan status epileptikus (5/9). Dari hasil systematic review ini, faktor yang paling berpengaruh terhadap epilepsi intraktabel pada anak adalah gangguan tumbuh kembang dengan odds ratio tertinggi 37,1 yang didapatkan pada studi Wirell et al, dan status epileptikus dengan odds ratio 32,9 yang didapatkan pada studi Yildiz et al. Faktor jenis kelamin durasi waktu kejang, riwayat keluarga epilepsy, dan riwayat kejang demam tidak berpengaruh signifikan terhadap epilepsy intaktabel. Sebagai kesimpulan, dalam penelitian ini ditemukan faktor yang paling berpengaruh terhadap epilepsi intraktabel pada anak adalah gangguan tumbuh kembang dan status epileptikus. Kata Kunci: Faktor Risiko, Epilepsy Intraktabel, Anak
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Lopes, Ana Filipa, José Paulo Monteiro, Maria José Fonseca, Conceição Robalo, and Mário Rodrigues Simões. "Memory Functioning in Children with Epilepsy: Frontal Lobe Epilepsy, Childhood Absence Epilepsy, and Benign Epilepsy with Centrotemporal Spikes." Behavioural Neurology 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/218637.

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Specific cognitive deficits have been identified in children with epilepsy irrespective of results on intelligence tests. Memory deficits are traditionally attributed to temporal lobe epilepsy, whereas the impact of frontal lobe epilepsy on memory functions has remained controversial. The aim of this study was the examination of memory abilities in other childhood common epilepsy syndromes (frontal lobe epilepsy (FLE), childhood absence epilepsy (CAE), and benign epilepsy with centrotemporal spikes (BECTS)) and the influence of epilepsy-related variables. Memory was examined in 90 children with epilepsy (each epilepsy group consisted of 30 children), aged 6–15, and compared with 30 control children. Children with FLE showed significant deficits in verbal and visual memory. In addition, type of epilepsy, earlier age at epilepsy onset, and longer active duration of epilepsy were associated with memory problems. Seizure frequency and treatment, however, did not influence memory performance. This study indicates that children with FLE show greater risk of developing memory deficits than children with CAE or BECTS, thus highlighting the importance of assessing also memory functions in frontal lobe epilepsy.
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Knezevic-Pogancev, Marija. "Cerebral palsy and epilepsy." Medical review 63, no. 7-8 (2010): 527–30. http://dx.doi.org/10.2298/mpns1008527k.

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Introduction. Cerebral palsy is the most common cause of physical disability in early childhood. Epilepsy is known to have a high association with cerebral palsy. All types of epileptic seizures can be seen in patients with cerebral palsy. Complex partial and secondary generalized ones are the most frequent seizure types. In persons with cerebral palsy and mental retardation, the diagnosis of epilepsy presents unique difficulties. Generally they are not able to describe the epileptic events themselves, parents are not able to describe them without fear and persons trained in epilepsy witness the events only rarely. Some syndromes, such as infantile spasms, West and Lennox-Gastaut syndrome, are particularly frequent, whereas children with cerebral palsy are rarely free of epilesy. It has been observed that epileptic seizures in children with cerebral palsy tend to have an earlier onset; they often appear in children with cerebral palsy and mental retardation; they are more severe in patients with a more severe degree of cerebral palsy. The overall outcome of seizures in children with cerebral palsy is poor, requiring prolonged course of antiepileptic medications, polytherapy with higher incidence of refractory seizures and hospital admissions for status epilepticus. The presence of a neurological deficit, as well as cerebral palsy, does not necessarily mean a poor prognosis after the discontinuation of antiepileptic drugs, but the risk of a relaps in persons with cerebral palsy is high. Aim. The objective of the paper was to show the relationship between cerebral palsy and epilepsy and to determine the occurrence, associated factors, nature and prognosis of epilepsy in children with cerebral palsy.
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Kirabira, Joseph, Ben Jimmy Forry, Robyn Fallen, and Bernard Sserwanga. "Perceived stigma and school attendance among children and adolescents with epilepsy in South Western Uganda." African Health Sciences 20, no. 1 (April 20, 2020): 376–82. http://dx.doi.org/10.4314/ahs.v20i1.43.

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Background: Epilepsy is a neurological disorder that has a high worldwide prevalence with eighty percent of the global burden being in low and middle-income countries. There is a high level of perceived stigma among children and adolescents with epi- lepsy, which has severe debilitating effects and affects school attendance. Objective: To assess the effect of perceived stigma on school attendance patterns among children and adolescents with epilepsy. Methods: We conducted a cross sectional study among 191 children and adolescents aged from 6-18 years with epilepsy at one large semi-urban hospital and a small rural health center in SouthWestern Uganda. Epilepsy-related perceived stigma was measured using the adapted Kilifi Stigma Scale of Epilepsy and school attendance patterns were assessed using a piloted inves- tigator-designed questionnaire. Results: Children with high-perceived stigma were more likely to have never attended school (13.8%) or started school late (average age 5.7 years) compared to those with low-perceived stigma (average age 4.9 years). Additionally, those with high epilep- sy-related perceived stigma repeated classes 2.5 times more compared to those with low-perceived stigma. Conclusion: These preliminary findings suggest correlation between high-perceived stigma and disrupted school attendance patterns among children and adolescents with epilepsy, hence the need to address this social challenge. Keywords: Epilepsy; perceived stigma; school attendance; children; adolescents; Uganda.
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Verity, C. "Epilepsy in Children." Journal of Neurology, Neurosurgery & Psychiatry 57, no. 10 (October 1, 1994): 1301–2. http://dx.doi.org/10.1136/jnnp.57.10.1301-b.

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Dissertations / Theses on the topic "Epilepsy in children"

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Nuttycombe, Rachael Eileen. "Parenting children with epilepsy." Thesis, University of Hull, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440230.

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Thomason, Kate Elizabeth. "Cognitive variiability in children with epilepsy." Thesis, University of Sheffield, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500107.

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Lunn, Judith. "Social understanding in children with epilepsy." Thesis, Lancaster University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656313.

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Children with epilepsy are at increased risk of communication and behavioural problems. Previous research has not assessed whether difficulties with social understanding are a contributory factor. This thesis contains three studies that addressed social cognitive reasoning and social attention in a group of children with epilepsy and typically developing children in mainstream education. The studies employed diverse methodologies to explore functioning in a number of cognitive and attention domains known to contribute to social understanding skills. The first study involved 55 children with epilepsy and 69 typically developing children. It employed social cognitive and social perceptual reasoning tasks, standardized assessments of IQ and expressive language and parental report measures of communication and behaviour. The findings suggest that children with epilepsy have difficulty with socio-cognitive reasoning that may be independent of functioning in other non-social domains. The degree of socio-cognitive impairment also predicted increased parental reports of communication and behaviour problems in some children. The second study involved 57 children (34 with epilepsy) and addressed bias in mental states attribution. It provides evidence that atypical mental states attribution is associated with poor executive function and attention in children with epilepsy who have increased reports of behavioural problems. The third study used eye tracking to assess social attention and inhibition to dynamic displays of gaze and emotion. It involved 59 children (25 with epilepsy). The children with epilepsy demonstrated atypical responding to gaze and emotion signals and performance was associated with increased reports of social problems. Overall, the findings suggest that social cognition and social attention are areas of vulnerability in some children with epilepsy.
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Stewart, Elizabeth Margaret. "Theory of Mind in Children with Epilepsy." Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20234.

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Epilepsy is a common neurological condition in childhood that is associated with significant social morbidity. Despite a high prevalence of social impairment in children with epilepsy, the factors underpinning social difficulties remain poorly understood and as a result, effective treatments are lacking. Two recent theoretical models of social competence proposed for children with epilepsy, central nervous system conditions, neurodevelopmental and acquired brain disorders have proposed that impairments in social cognition (i.e. Theory of Mind [ToM]) may be related to social impairments in this group. The aims of the thesis were to: (1) study ToM and its relationship to social competence in children and adolescents with genetic generalised epilepsy (GGE) and temporal lobe epilepsy (TLE), and (2) determine whether social impairments could be remediated by targeting ToM. First, we conducted a systematic review and meta-analysis, which revealed significant ToM impairments in adults with epilepsy and a dearth of research in children with epilepsy (Chapter 2). Second, we conducted two empirical studies assessing ToM and social competence in children (8-16 years old) with GGE (Chapter 3) and TLE (Chapter 4); we found evidence of significant ToM impairments that were related to social problems in both epilepsy groups. Third, we developed a novel cognitive behavioural intervention with ToM training for children with epilepsy (Chapter 5), published a study protocol (Chapter 6) and evaluated the intervention in pilot study (Chapter 7); results from the pilot study provided preliminary evidence that the intervention was feasible, acceptable, safe, and a potentially effective way of remediating social problems in our target group. In conclusion, these studies have shown that: (1) children with GGE and TLE have significant impairments in ToM, and associated social problems, and (2) social difficulties can be potentially remediated by targeting ToM impairments in this group.
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Gascoigne, Michael. "Long-term memory in children with epilepsy." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10216.

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Memory difficulties represent a common complaint in patients with epilepsy. These difficulties may refer to (i) a faster rate of forgetting of newly-learned materials over long delays relative to short delays (accelerated long-term forgetting; ALF) or (ii) autobiographical memory (ABM) difficulties, including deficits in recall of episodic (re-experiencing of personal events) and semantic (factual information) components. To date, ALF and ABM studies have largely focussed on adults. This thesis assesses ALF and ABM in children with temporal lobe epilepsy (TLE) and in those with idiopathic generalised epilepsy (IGE). ALF is assessed in 23 children with TLE, 20 with IGE and 58 similarly-matched controls. Participants completed a battery of tests, including a measure of verbal learning and recall after short (30-min) and long (7-day) delays. Relative to controls, children with TLE recalled fewer words at the 7-day delay compared with the 30-min delay. Age was also negatively correlated with word recall after short and long delays within the TLE group. Children with IGE recalled fewer words after a long, but not short, delay relative to controls. Moreover, greater epilepsy severity was associated with poorer 7-day recognition in the IGE group. ABM was assessed in 21 children with TLE, 18 with IGE and 42 healthy controls. Children with TLE recalled fewer episodic, but not semantic, details than controls. Unlike controls, episodic recall did not increase with age in the TLE group and was unrelated to epilepsy factors, such as side of seizure focus. Children with IGE recalled fewer episodic details than controls while earlier age of seizure onset was associated with poorer episodic recall. Our findings suggest that long-term memory consolidation may be disrupted by temporal lobe pathology or seizure focus and generalised seizures. Finally, long-term memory deficits may gradually emerge in children with TLE, as older children are more likely to present with these deficits.
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Neri, Marina Liberalesso 1980. "Avaliação neuropsicológica de crianças com epilepsia rolândica = funções executivas." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309169.

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Orientadores: Marilisa Mantovani Guerreiro, Catarina Abrão Guimarães
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
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Resumo: A epilepsia benigna da infância com pontas centrotemporais (EBIPCT) ou rolândica (ER) é a forma mais freqüente de epilepsia na infância e é classificada como sendo focal, genética e de evolução benigna. Apesar de não haver déficit intelectual, essas crianças podem apresentar alterações cognitivas específicas. O presente estudo teve como objetivos: identificar e descrever alterações de funções executivas em crianças com ER e verificar a influência de variáveis clínicas da epilepsia nas funções executivas. Os participantes foram submetidos à aplicação de testes de funções executivas. Foram incluídas crianças com diagnóstico clínico e eletroencefalográfico de ER. A maioria dos pacientes estava controlada e muitos deles encontravam-se sem medicação. Os resultados obtidos foram comparados com os de um grupo de crianças de um grupo-controle (GC) constituído de indivíduos normais, com idade e nível sócio-educacional semelhantes ao das crianças com epilepsia. Os dados coletados nos dois grupos foram analisados e comparados através dos testes estatísticos: Mann-Whitney, teste Qui-quadrado e teste Exato de Fisher. Os resultados mostraram que quanto aos dados numéricos crianças com ER obtiveram pior desempenho em cinco das seis categorias consideradas do Wisconsin Card Sorting Test (WCST): nº de erros, nº de erros perseverativos, nº de respostas perseverativas, nº de categorias completadas e nº de fracassos em manter o set. Considerando-se resultados categóricos crianças com ER obtiveram pior desempenho no Trail Making Test (TMT) parte B, no Teste de fluência verbal FAS e em três categorias do WCST: nº de erros, nº de erros perseverativos e nº de respostas perseverativas. Em relação à variável idade de início da epilepsia, crianças com início mais precoce apresentaram pior desempenho em um dos instrumentos utilizados quando comparadas com crianças com início mais tardio da epilepsia; em relação às demais variáveis da epilepsia, não foi possível qualquer tipo de análise; quanto às variáveis das crises, não houve diferença nos resultados obtidos pelos pacientes divididos em grupos. Diante desses resultados concluímos que: as crianças com ER apresentaram déficit em funções executivas quando comparadas com o grupo-controle; a bateria utilizada mostrou-se adequada para detecção das disfunções apresentadas pelas crianças com ER; em relação à variável da epilepsia idade de início, crianças com início mais precoce apresentaram pior desempenho do que crianças com início mais tardio da epilepsia; em relação às demais variáveis da epilepsia e às variáveis das crises, não houve diferença entre os dois grupos. Assim, nosso estudo segue a linha de raciocínio de que o termo benigno deve ser usado com cautela uma vez que nossos pacientes apresentaram déficits neuropsicológicos em funções executivas, independentemente da fase ativa da epilepsia e do uso de medicações
Abstract: The benign childhood epilepsy with centrotemporal spikes (EBIPCT) or rolandic epilepsy (RE) is the most common type of childhood epilepsy and is considered to be a focal, genetic and benign epilepsy. Although there is no intellectual deficit, these children may have specific cognitive impairments. This study aimed: to identify and describe changes in executive functions in children with RE and to verify the influence of clinical variables of epilepsy in executive functions. Participants were evaluated with tests to assess executive functions. We included children with clinical and EEG features of RE. Most patients were controlled and several were without medication. The results were compared with those of a control group (CG) comprised of normal subjects with age and socioeconomic level similar to that of the RE group. The data collected from both groups were analyzed and compared using statistical tests: Mann-Whitney, Chi-square and Fisher exact tests. The results showed that concerning the numerical data, children with RE had the worst performance in five of the six categories of the WCST: number of errors, number of perseverative errors, number of perseverative answers, number of completed categories and number of failures to maintain the set. Considering categorical results, children with RE had worse performance in Trail Making Test part B, Verbal fluency test FAS and three categories of the WCST: number of errors, number of perseverative errors and number of perseverative answers. Concerning the variable age of onset of epilepsy, children with earlier onset of epilepsy had a worse performance in one of the tools when compared with children with later onset of epilepsy; the other variables of epilepsy did not allow any analysis; considering seizure variables, there was no difference between the two groups. We conclude that: children with RE showed deficits in executive functions when compared with the control group; the set of tests was adequate to detect the dysfunctions presented by children with RE; in relation to the variable age of onset of epilepsy, children with earlier onset had a worse performance than children with later onset of epilepsy; concerning other epilepsy and seizure variables, there was no difference between the two groups. Thus, our study is in keeping with the idea that the term benign should be cautiously used since our patients had neuropsychological deficits in executive functions regardless of the active phase of epilepsy and the use of medications
Doutorado
Ciencias Biomedicas
Doutor em Ciências Médicas
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Beresford, Bryony. "Coping with epilepsy in childhood : an examination into factors mediating adjustment in children with epilepsy." Thesis, University of Exeter, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316379.

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Corrigan, Fiona MacDonald. "Sleep and forgetting in children with genetic generalised epilepsy." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6695/.

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Objective: Given the well-established association between epilepsy and sleep disturbance and the evidence suggesting the importance of sleep in memory consolidation, there is reason to investigate the relationship between sleep and rate of forgetting in children with epilepsy. This study aimed to investigate the relationship between sleep and forgetting in children with Genetic Generalised Epilepsy (GGE). Methods: Participants were 19 children with GGE (9-15 years old). Actigraphy, sleep diaries and standardised questionnaires were used to measure sleep over a week long period. Rate of forgetting was measured using neuropsychological tests at the beginning and end of the study week. Spearman’s correlation analysis was used to determine if poorer sleep was associated with poorer initial learning and rate of forgetting in verbal memory recall and recognition. Results: No association was found between sleep efficiency or duration and rate of forgetting. Measures of sleep disturbance were mixed, with sleep onset latency found to be associated with rate of forgetting on the Word Lists test. However, increased wake after sleep onset was associated with decreased rate of forgetting. Conclusions: Whilst there was limited evidence of a relationship between some actigraphic sleep parameters and rate of forgetting for verbal information, the results were mixed and likely biased by the small sample size. There is need for further research with a larger sample to establish the nature of the relationship between sleep and rate of forgetting in children with GGE.
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Costolo, Megan. "Evidence-Based Intervention for Families of Children with Epilepsy." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/203001.

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The purpose of this paper is to propose an evidence-based intervention guideline to increase effective coping and positive adaptation in families with a preschool age child who has epilepsy. This population was chosen because there is a lack of research regarding interventions for families of preschool age children with epilepsy. Relevant literature was reviewed to summarize the effects of childhood epilepsy on families, and to assess the effectiveness of interventions to improve coping and adaptation in these families. The main stressors caused by epilepsy are knowledge deficits about epilepsy, knowledge deficits about treatments for epilepsy, increased seizure frequency, and emotional disturbances caused by epilepsy. Prior interventions for families of children with epilepsy included psychoeducational programs, support groups, education programs, family counseling groups, and therapeutic alliance. All interventions in the studies reviewed had positive outcomes for families of children with epilepsy. However, psychoeducational programs tended to address all of the common stressors, whereas other interventions did not. This paper provides an evidence-based intervention guideline for families affected by epilepsy. The significance and limitations of the program are discussed, and recommendations for future research in this area are presented.
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Parker, Alasdair Patrick John. "The investigation and management of children with epileptic encephalopathies." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391613.

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Books on the topic "Epilepsy in children"

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J, Wallace Sheila, ed. Epilepsy in children. London: Chapman & Hall Medical, 1996.

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J, Wallace Sheila, and Farrell Kevin, eds. Epilepsy in children. 2nd ed. London: Arnold, 2004.

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Renzo, Guerrini, Aicardi Jean, and Aicardi Jean, eds. Aicardi's epilepsy in children. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2004.

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Rogan, Peter J. Epilepsy: The detective's story. Lancaster: Quay, 1987.

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Rogan, Peter J. Epilepsy: A teacher's handbook. 2nd ed. (Liverpool): Roby Education for Mersey Region Epilepsy Association, 1986.

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Matti, Sillanpää, ed. Paediatric epilepsy. Petersfield: Wrightson Biomedical Pub., 1990.

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Wheless, James W., ed. Epilepsy in Children and Adolescents. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781119998600.

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1951-, Aldenkamp A. P., ed. Epilepsy in children and adolescents. Boca Raton: CRC Press, 1995.

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Cascino, Gregory. Adult epilepsy. Chichester, West Sussex, UK: Wiley-Blackwell, 2011.

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1949-, Reisner Helen, ed. Children with epilepsy: A parents guide. Kensington, MD: Woodbine House, 1988.

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Book chapters on the topic "Epilepsy in children"

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Gillham, Ruth. "Epilepsy." In Handicapping Conditions in Children, 74–89. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003261964-6.

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Stephen Huff, J., and Jessica L. Carpenter. "Acute Symptomatic Seizures in Children and Adults." In Epilepsy, 215–21. Oxford: John Wiley & Sons, 2014. http://dx.doi.org/10.1002/9781118456989.ch30.

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Sassen, Robert, and Horst Urbach. "MRI of Children." In MRI in Epilepsy, 37–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/174_2012_560.

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Reilly, Colin, and Christopher Gillberg. "Epilepsy." In Comorbid Conditions Among Children with Autism Spectrum Disorders, 235–56. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19183-6_10.

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Jain, Sejal V., and Sanjeev V. Kothare. "Sleep and Epilepsy." In Sleep Disorders in Children, 337–55. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-28640-2_15.

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Nickels, Katherine. "Focal Seizures in Children." In Epilepsy Case Studies, 33–36. Cham: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-01366-4_8.

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Delalande, O. "Epilepsy Surgery in Children." In Practical Handbook of Neurosurgery, 1109–15. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-84820-3_66.

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Theisler, Charles. "Epilepsy—Status Epilepticus (Children)." In Adjuvant Medical Care, 122. New York: CRC Press, 2022. http://dx.doi.org/10.1201/b22898-130.

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Hyslop, Ann. "Epilepsy Surgery in Children." In Handbook of Pediatric Epilepsy Case Studies, Second Edition, 67–76. 2nd ed. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003296478-8.

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Gertsch, Emily A., and Kelly Knupp. "Do Children “Outgrow” Epilepsy?" In Curbside Consultation in Pediatric Neurology, 33–36. Boca Raton: CRC Press, 2024. http://dx.doi.org/10.1201/9781003523659-9.

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Conference papers on the topic "Epilepsy in children"

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Bajaj, Jitin, P. Sarat Chandra, Bhargavi Ramanujam, Shabari Girishan, Ramesh Doddamani, and Manjari Tripathi. "Hemispherotomy in Adults. Is It Safe?—A Prospective Observational Study in Comparison to Children." In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694874.

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Agarwal, Ekta, Srivastava K., and Rajadhyaksha S. "Changing Trends of Subacute Sclerosing Panencephalitis— Pre- and Postvaccination Era, Why Should Children Vaccinated against Measles Develop SSPE?" In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694867.

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Goud, G. V. K. R., Vasavi Chinta, Rukmini Mrudula, and Rupam Borgohain. "Perception of Epilepsy Stigma in School Children and Teachers’ Awareness and Attitude towards Epilepsy—A South Indian Cohort Study." In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694870.

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Pilina, Guzel. "389 Cognitive disorder in children with epilepsy." In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.389.

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U., Saraf U., Asranna A., Menon R. N., Radhakrishnan A., Manju P., Vibina V. P., Cherian A., and Thomas S. V. "Electroclinical Predictors of Cognitive and Seizure Outcome in Children with Epileptic Encephalopathy Due to Electrical Status Epilepticus in Sleep (ESES)." In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694859.

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Yadav, Sidharth, Suvasini Sharma, Bijoy Patra, Rajeev Malhotra, and Virendra Kumar. "Status Epilepticus in Pediatric Patients Severity Score (STEPSS): A Clinical Score to Predict the Outcome of Status Epilepticus in Children." In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694897.

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Vanags, Edmunds, Ņikita Bezborodovs, Līga Riekstiņa, Armands Zelčs, Lelde Ūlupe, Dana Skara, Ance Vecgrāve, Marta Celmiņa, and Jurģis Strautmanis. "Cognitive Abilities in Children with ADHD, Comorbid Epilepsy and Typically Developed Children." In 80th International Scientific Conference of the University of Latvia. University of Latvia Press, 2022. http://dx.doi.org/10.22364/htqe.2022.01.

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The aim of the study was to assess the differences in cognitive abilities compared across clinical and control groups. It was hypothesized that differences between groups would be small or non-existant, due to rather heterogeneous clinical profiles. And they could be partially explained by participants’ age as cognitive abilities develope over time. Further analysis of the sample was performed by creating cognitive ability profiles of the participants. The study used data from the project “Development of a Screening Method for Children with ADHD and CSWS in Children aged 7–15”, and included data from 97 children, which were divided into 3 groups: ADHD, combined ADHD and epilepsy and control group. For assessing cognitive abilities an extended battery of executive and other cognitive computerized tests were used: Stroop Color and Word Test, Digit Span Test, Symbol Digit Modalities Test, and Continious Performance Test. The analysis of cognitive ability profiles reveals a wide range of heterogeneity in both clinical and control groups. It revealed that children with ADHD and combined ADHD and epilepsy have more profiles with lower cognitive abilities compared to control group. Some children with ADHD have similar cognitive profiles to those of typically developed children, suggesting that in some cases there may be a small difference in cognitive performance between ADHD and typically developed children.
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Jose, Manna, Veena P., Nikita Susan Jacob, and Sanjeev V. Thomas. "Children (12–18 Years Age) of Women with Epilepsy Have Lower Intelligence, Attention, and Memory: Observations from the Kerala Registry of Epilepsy and Pregnancy." In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694882.

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S., Mishra, Mallick A. K., Mohanty G., and Biswal N. "Use of Early Childhood Epilepsy Severity Scale (E-Chess) in Classification and Prognostication of Children with West Syndrome: A Study from Tertiary Care Pediatric Neurology Centre." In 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association. Thieme Medical and Scientific Publishers Private Ltd., 2018. http://dx.doi.org/10.1055/s-0039-1694895.

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Shanah, Hoda. "1527 Neurocognitive assessment for children with idiopathic epilepsy." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference–Online, 15 June 2021–17 June 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-rcpch.700.

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Reports on the topic "Epilepsy in children"

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Sun, Yang, Jing Zhao, PanWen Zhao, Hui Zhang, JianGuo Zhong, PingLei Pan, GenDi Wang, ZhongQuan Yi, and LILI Xie. Social cognition in children and adolescents with epilepsy: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2022. http://dx.doi.org/10.37766/inplasy2022.3.0011.

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Review question / Objective: To our knowledge, no meta-analysis has summarized social cognitive performance in children and adolescents with epilepsy as independent groups. Therefore, we conducted this meta-analysis to examine differences between children and adolescents with epilepsy and HCs in terms of ToM and FER performance. Condition being studied: Epilepsy is characterized by chronic, unprovoked and recurrent seizures, is the most frequent neurological disease in childhood and usually occurs in early development. Worldwide, it is estimated that approximately 50 million people suffer from the pain of epileptic seizures, with more than half of the cases beginning in childhood and adolescence. So a comprehensive understanding of children and adolescence with epilepsy has become the focus of widespread attention. Recently, a number of studies have assessed ToM or facial emotion recognition deficits in children and adolescents with epilepsy, but the conclusions are inconsistent. These inconsistent findings might be related to the small sample sizes in most studies. Additionally, the methods used to evaluate ToM or facial emotion recognition performance were varied across studies. A meta-analysis can increase statistical power, estimate the severity of these deficits, and help resolve conflicting findings.
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Zhao, Shouju, and Xianqiong Feng. The effectiveness of mobile health intervention in children and adolescent with epilepsy :A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2024. http://dx.doi.org/10.37766/inplasy2024.3.0087.

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Ji, Lang, Yitong Chen, Rui Chen, Jianzhao Zhang, Bojing Tan, and Linghui Meng. Efficacy and Tolerability of Lamotrigine in the Treatment of Focal Epilepsy in Children and Adolescents: A Systematic Review and Meta-analysis. International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2020. http://dx.doi.org/10.37766/inplasy2020.5.0013.

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Wu, Xiaofang, Zhonghai Zhu, and Yongsheng Jiang. Meta-analysis of the effects of sodium valproate (VPA), levetiracetam (LEV) and oxazepine (OXC) on cognitive level of Chinese benign epilepsy children with central temporal spike (BECT). INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0066.

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Treadwell, Jonathan R., Mingche Wu, and Amy Y. Tsou. Management of Infantile Epilepsies. Agency for Healthcare Research and Quality (AHRQ), October 2022. http://dx.doi.org/10.23970/ahrqepccer252.

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Objectives. Uncontrolled seizures in children 1 to 36 months old have serious short-term health risks and may be associated with substantial developmental, behavioral, and psychological impairments. We evaluated the effectiveness, comparative effectiveness, and harms of pharmacologic, dietary, surgical, neuromodulation, and gene therapy treatments for infantile epilepsies. Data sources. We searched Embase®, MEDLINE®, PubMed®, the Cochrane Library, and gray literature for studies published from January 1, 1999, to August 19, 2021. Review methods. Using standard Evidence-based Practice Center methods, we refined the scope and applied a priori inclusion criteria to the >10,000 articles identified. We ordered full text of any pediatric epilepsy articles to determine if they reported any data on those age 1 month to <36 months. We extracted key information from each included study, rated risk of bias, and rated the strength of evidence. We summarized the studies and outcomes narratively. Results. Forty-one studies (44 articles) met inclusion criteria. For pharmacotherapy, levetiracetam may cause seizure freedom in some patients (strength of evidence [SOE]: low), but data on other medications (topiramate, lamotrigine, phenytoin, vigabatrin, rufinamide, stiripentol) were insufficient to permit conclusions. Both ketogenic diet and the modified Atkins diet may reduce seizure frequency (SOE: low for both). In addition, the ketogenic diet may cause seizure freedom in some infants (SOE: low) and may be more likely than the modified Atkins diet to reduce seizure frequency (SOE: low). Both hemispherectomy/hemispherotomy and non-hemispheric surgical procedures may cause seizure freedom in some infants (SOE: low for both), but the precise proportion is too variable to estimate. For three medications (levetiracetam, topiramate, and lamotrigine), adverse effects may rarely be severe enough to warrant discontinuation (SOE: low). For topiramate, non-severe adverse effects include loss of appetite and upper respiratory tract infection (SOE: moderate). Harms of diets were sparsely reported. For surgical interventions, surgical mortality is rare for functional hemispherectomy/hemispherotomy and non-hemispheric procedures (SOE: low), but evidence was insufficient to permit quantitative estimates of mortality or morbidity risk. Hydrocephalus requiring shunt placement after multilobar, lobar, or focal resection is uncommon (SOE: low). No studies assessed neuromodulation or gene therapy. Conclusions. Levetiracetam, ketogenic diet, modified Atkins diet, and surgery all appear to be effective for some infants. However, the strength of the evidence is low for all of these modalities due to lack of control groups, low patient enrollment, and inconsistent reporting. Future studies should compare different pharmacologic treatments and compare pharmacotherapy with dietary therapy. Critical outcomes underrepresented in the literature include quality of life, sleep outcomes, and long-term development.
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Mental Health Intervention for Children with Epilepsy - recording. ACAMH, May 2023. http://dx.doi.org/10.13056/acamh.23917.

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