Academic literature on the topic 'Épidémiologie des rayonnements ionisants'
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Journal articles on the topic "Épidémiologie des rayonnements ionisants"
Samson, E., K. Leuraud, E. Rage, S. Caër-Lorho, S. Ancelet, E. Cléro, S. Bouet, et al. "Bilan de la surveillance épidémiologique des travailleurs du cycle électronucléaire en France." Radioprotection 53, no. 3 (July 2018): 175–84. http://dx.doi.org/10.1051/radiopro/2018026.
Full textMasse, Roland. "Rayonnements ionisants." Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie 323, no. 7 (July 2000): 633–40. http://dx.doi.org/10.1016/s0764-4469(00)00160-8.
Full textWassilieff, S. "Cataracte et rayonnements ionisants." Radioprotection 44, no. 4 (October 2009): 505–17. http://dx.doi.org/10.1051/radiopro/2009020.
Full textCoffigny, H., and B. Dutrillaux. "Effets héréditaires des rayonnements ionisants." Revue Générale Nucléaire, no. 3 (May 2004): 33–36. http://dx.doi.org/10.1051/rgn/20043033.
Full textAurengo, A. "Effets biologiques des rayonnements ionisants." Journal de Radiologie 89, no. 10 (October 2008): 1277. http://dx.doi.org/10.1016/s0221-0363(08)75804-9.
Full textAurengo, A. "Effets biologiques des rayonnements ionisants." Journal de Radiologie 90, no. 10 (October 2009): 1240. http://dx.doi.org/10.1016/s0221-0363(09)74959-5.
Full textLaroche, P. "Rayonnements ionisants : ombres et lumières." Archives des Maladies Professionnelles et de l'Environnement 70, no. 4 (September 2009): 371–72. http://dx.doi.org/10.1016/j.admp.2009.06.001.
Full textBOBYK, L., and M. VALENTE. "Le Laboratoire de Dosimétrie Biologique des Irradiations." Revue Médecine et Armées, Volume 50, Numéro 2 (June 6, 2024): 39–48. http://dx.doi.org/10.17184/eac.8637.
Full textBranchet, Éric, Simone Jaffre, and Brigitte Gougeon. "Les rayonnements ionisants à usages thérapeutiques." La Revue de l'Infirmière 64, no. 214 (October 2015): 47–48. http://dx.doi.org/10.1016/j.revinf.2015.07.015.
Full text-WOLF, Pr Didier. "Rayonnements ionisants appliqués à la médecine." Revue de l'Electricité et de l'Electronique -, no. 03 (2000): 79. http://dx.doi.org/10.3845/ree.2000.028.
Full textDissertations / Theses on the topic "Épidémiologie des rayonnements ionisants"
Chauveinc, Laurent. "Etudes génétiques des tumeurs radio-induites." Paris 11, 2001. http://www.theses.fr/2001PA11T040.
Full textRadiation induced tumors are a possible very late complications of radiotherapy. Many epidemiologist studies exists, with the evaluation of the relative risk for different tissues. But, the genetic studies are rare, and no global theory exists. With the published cases, two profiles existed, one with translocations and one with genetic material losses, evoking two different genetic evolutions. In this work, a few ways to explain the chromosomic evolution of the radiation-induced tumors were explored. In the fust part, with study of the age and the latency period of second tumor after retinoblastomas, two or more genes were modified by the irradiation. With 12 cytogenetic cases, analyzed in the laboratory, and the 25 cases of the literature, the radiation-induced tumors were characterized by genetic material losses. A anti-oncogenic evolution is probable. Only thyroid tumors did not have this evolution. The mechanism of the chromosomic material losses could be the chromosomic instability. The telomere length decreasing is a possible explanation of these phenomena. In our preliminary results, the telomere length of radiation-induced tumor did not decrease comparing to normal human cells, suggesting that telomerase activity stabilized this length
Fournier, Lucie. "Effets sanitaires d’une exposition chronique à de faibles doses de rayonnements ionisants : contribution à l’estimation des risques radio-induits de cancers dans une cohorte française de travailleurs du nucléaire." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS251/document.
Full textThe aim of the thesis is to study three potential sources of bias in the analyses on the cancer risk associated with chronic external exposure to low doses of ionizing radiation in the CEA-AREVA-EDF cohort. This cohort includes 59 004 nuclear workers from those companies who were badge-monitored for external exposure to radiation. The first part of this thesis is devoted to potential internal exposure to radionuclides among the workers. Given the lack of available individual data on internal contaminations, a flag attributing for each worker and for each year a potential contamination risk based on workstations was defined and added to the analyses on cancer mortality risk associated with external radiation exposure. The second part of this work focuses on non-occupational exposures to radiation.Nuclear workers are exposed to radiation from environmental and medical sources, in particular from radiological examinations carried out in an occupational health framework. Scenarios characterising non-occupational exposures to radiation were constructed and their impact on the cancer mortality risk associated with occupational exposure was examined. The third part of this thesis addresses dosimeters recording thresholds. Below those thresholds, dose quantification is deemed too imprecise. Historically, below the threshold doses were recorded as null, resulting in systemic dose underestimation. A comprehensive review of the dosimetry practices in the cohort was accomplished and led to the conception of scenarios aiming to impute below the threshold
Lopes, Julie. "Analyse du risque radio-induit de décès chez les professionnels de santé exposés aux rayonnements ionisants." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASR020.
Full textAbstract: Studies of workers exposed to ionizing radiation enable the characterization of health effects resulting from chronic low-dose exposure. Although extensive research has been carried out on the subject, there are still uncertainties surrounding the quantification of these effects. To date, medical workers represents the largest group of workers occupationally exposed to artificial sources of ionizing radiation. Their subsequent risk of various pathologies is therefore an important subject of study. Nevertheless, the conclusions of these studies are uncertain and debated, particularly regarding the risk of developing tumors of the central nervous system (CNS).Based on literature reviews supported by meta-analyses and on statistical analyses of data collected as part of the epidemiological follow-up of the ORICAMs (Occupational Radiation Induced Cancer in Medical staff) cohort, this thesis aims to improve knowledge of the effects of ionizing radiation on health in the context of low-dose exposure.A mortality analysis was carried out on the ORICAMs cohort, including 164 015 medical workers occupationally exposed to ionizing radiation in France, presenting at least one dosimetric record between 2002 and 2012. Mortality was significantly lower in the ORICAMs cohort than in the general population. However, these results based on a comparative analysis with national rates may be influenced by the healthy worker effect, and do not allow to conclude on the existence or not of a potential relationship between occupational exposure and the risk of death. To address this issue, a case-control study nested within the ORICAMs cohort was set up, including 33 cases and 160 controls. However, conditional logistic regression analyses showed no dose-response relationship between occupational exposure to ionizing radiation and death from CNS tumors. An extension of the cohort follow-up and the inclusion of the case-control study in the international BECOME project will increase the statistical power of the analyses, allowing the assessment of the long-term effects of chronic exposure to low doses of ionizing radiation
Metz-Flamant, Camille. "Effets sanitaires des faibles doses a faibles debits de dose : modélisation de la relation dose-réponse dans une cohorte de travailleurs du nucléaire." Thesis, Paris 11, 2011. http://www.theses.fr/2011PA11T047/document.
Full textThe aim of this thesis is to contribute to a better understanding of the health effects of chronic extern allow doses of ionizing radiation. This work is based on the French cohort of CEA-AREVA NC nuclear workers. A review of epidemiological studies on nuclear workers was conducted during the first yearof the PhD thesis. The quantification of the dose-response relationship has been carried out by different statistical methods. Modifying factors of the leukaemia dose-response relationship were studied. A combined analysis including the present cohort together with other nuclear cohorts could quantify more precisely the risks associated to low doses at low dose rates, in order to validate current underlying hypotheses of the radiation protection system
Fendler, Julie. "Approches hiérarchiques bayésiennes pour l'estimation d'un risque sanitaire induit par l'exposome professionnel (co-expositions radiologiques à faibles doses sujettes à des erreurs de mesure) : Application à la cohorte française des mineurs d'uranium." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASR019.
Full textThe population of uranium miners is a reference population for studying the health effects of chronic exposure to various sources of ionising radiation (IR): radon, gamma rays and uranium dust. However, two statistical problems arise in these studies: 1) the miners' exposures measures are error-prone; 2) the exposures to the three sources of IR are highly correlated. In radiation epidemiology, measurement errors in exposures are often ignored and health risks are estimated source by source, ignoring the synergistic or antagonistic effects of simultaneous exposures. The aim of this work, which is divided into two parts, is to promote the use of hierarchical Bayesian models to address the two problems raised above. All the statistical methods proposed in this work are applied to estimate a health risk from survival data in the French cohort of uranium miners.A model is proposed for estimating a health risk while considering complex measurement errors on radon exposures. These measurement errors depend on the miner's workplace and its work habits which change little over time. These errors are therefore spatially and temporally correlated. They are also heteroscedastic: their variances decrease over time as methods for assessing radon exposure improve. The proposed models are used account for measurement errors in radon exposure when estimating the risk of death by lung cancer, kidney cancer, brain and central nervous system cancer and leukaemia. The correction of the measurement errors and the estimation of the health risk are carried out simultaneously so that the estimation of the risk coefficient account for the uncertainty in the exposures. An MCMC algorithm was implemented in Python 3.8 to infer the model within a Bayesian framework. A simulations study is then carried out to estimate the impact of model misspecification on risk estimates.The three exposures to IRs are considered simultaneously when assessing a health risk by using profil regressions mixture (PRM) models. These models are used to create groups of miners with similar exposure profiles and similar health risks. As before, the inference of groups and the estimation of health risk are carried out simultaneously so that the uncertainty in the grouping is accounted in the estimation of risk. The number of groups in the model is infinite, but only a finite number of groups are non-empty. This assumption, which implies that the number of model parameters is infinite, introduces a difficulty in inferring the model. In addition, the output of the inference algorithm cannot be interpreted directly: post-processing must be carried out in order to form the different groups of individuals. While the choice of post-processing used has an impact on the grouping of individuals, there are only few guidelines on this in the scientific literature. This work proposes a Python implementation of a time-efficient MCMC algorithm for inferring PRM models. This algorithm is used to estimate the risk of death from lung cancer in the French cohort of uranium miners associated with simultaneous exposure to radon, gamma rays and uranium dust. Finally, a simulation study is carried out to compare different post-treatment procedures and provide guidelines on their use
Metz, Camille. "Effets sanitaires des faibles doses a faibles debits de dose : modélisation de la relation dose-réponse dans une cohorte de travailleurs du nucléaire." Phd thesis, Université Paris Sud - Paris XI, 2011. http://tel.archives-ouvertes.fr/tel-00647339.
Full textJourny, Neige. "Analyse de la relation entre l’exposition aux rayonnements ionisants lors d’examens de scanographie et la survenue de pathologie tumorale, au sein de la cohorte « Enfant Scanner »." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T065/document.
Full textComputed tomography (CT) is a powerful imaging technique that provides great benefits for diagnosis and medical management of patients. Nonetheless, the widespread use of this procedure raises many concerns about the potential adverse effects induced by X-rays exposure, both in clinical practice and in terms of public health. First epidemiological studies have suggested an increased risk of cancer associated with CT scan exposures in childhood or adolescence. The interpretation of these results is, however, controversial, and evidence about radiation-induced risks of cancer is still limited at this level of exposure and during childhood.In France, the "Enfant Scanner" cohort was set up by IRSN to study the incidence of cancer among more than 100,000 children who received CT scans before the age of 10 in 21 university hospitals. This study is part of the European Epi-CT project – coordinated by the International Agency for Research on Cancer – which includes nine national cohorts set up on the basis of a common protocol. The current thesis, based on the French cohort, focuses on characterizing the exposure of children receiving diagnostic CT scans and quantifying the risk of cancer associated with these exposures.Dosimetric assessment was performed from the radiological protocols used in paediatrics between 2000 and 2011 in the participating hospitals. This study presents the evolution of the exposures during the period and the variability of practices in the radiology departments. The results show that there is a leeway for optimizing the procedures and limiting the exposure of patients, especially for scans of the head that account for most of the examinations in paediatrics.From these exposure measurements, a quantitative assessment of cancer risk potentially induced by CT scans in paediatrics was performed – on the basis of estimates of risk in other contexts of ionizing radiation exposure. The results show that each CT scan could be associated with an excess risk of tumours of the central nervous system, breast cancer, thyroid cancer or leukaemia ranging from 0.01‰ to 5‰. Cancer risks may be up to 7 times higher for patients aged 1 year compared to 10 year olds. Uncertainties attached to these risk predictions were quantified by simulations.From the follow-up of cancer incidence in the cohort, the dose-response relation was studied between the risk of tumors of the central nervous system, leukaemia and lymphoma, and cumulative X-ray doses to the organs of interest from CT scans. No significant increased risk was observed. Indeed, in 2011, the duration of the follow-up, i.e. 4 years on average, was very short. The analyzes have nevertheless characterized the impact of (acquired or hereditary) immunodeficiencies and other genetic factors predisposing to cancer on the risk estimates, and highlighted the importance of considering the indication of examinations in studies on CT scans.The follow-up of the cohort should be extended to provide more robust risk estimates. Extension of this study as well as expected results from other cohorts, particularly within the Epi-CT project, would provide, in the next 5 years, significant progresses on the issue of the potential adverse effects of CT. To date, risk predictions from quantitative risk assessment are still uncertain, especially for cerebral tumours, but should help to guide the use of CT. In addition, efforts for optimizing the radiological procedures are still needed to reduce the doses delivered in paediatrics and the potential associated risks
Demoury, Claire. "Variations géographiques de l’incidence des leucémies de l’enfant et association avec l’exposition aux radiations ionisantes d’origine naturelle." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T027/document.
Full textIonizing radiation due to medical or accidental exposure to high doses is an established risk factor for leukemia in humans. However, the evidence of a risk associated with exposure to ionizing radiation at lower levels usually encountered in the environment remains to be demonstrated. Our work aims to evaluate the hypothesis of the existence of an association between natural background ionizing radiation and the risk of childhood leukemia (CL) using observations made in France.Leukemia cases included in this study are all the CL recorded in the National Registry of Childhood Hematological Malignancies, an exhaustive repository of all cases of patients younger than 15 years old in France over the studied period.First step was the study of the spatial distribution of the incidence of CL at the level of the 1,916 Living Zone (LZ) defined by INSEE. Cluster detection methods have been used on 7,675 cases of CL diagnosed during the period 1990-2006 to identify areas potentially associated with a higher risk of acute childhood leukemia. The study did not show any spatial heterogeneity of incidence of CL during the period at LZ level. However, some spatial clusters were highlighted in specific places and times. Although the levels of significance of these clusters do not strongly support the existence of risk factors, localized clusters can show a slight impact of risk factors shared across LZ, including contextual environmental exposures.To test the hypothesis of the existence of an association between environmental exposure to ionizing radiation of natural origin and incidence of childhood leukemia, an incidence study based on 9,056 cases of CL for the period 1990-2009 was conducted. This study was complemented by a record-based cases-controls study based on the 2,763 cases of CL recorded over the 2002-2007 period and a control set of 30,000 subjects constituting a representative sample of the contemporary French pediatric population. In this approach, localizations of cases and controls and exposure identifications were geocoded and compared to the status cases vs control population.Data of exposure to natural background radiation were produced by the IRSN (Institute for Radiological Protection and Nuclear Safety). Mapping of the “potential radon exhalation emitted by the ground” and a national sampling of 10,843 measurement points located in dwellings were used to estimate residential exposure to radon at a level of granularity of cities and houses. Exposure to terrestrial gamma and cosmic rays was estimated by zone d’emploi based on a set of more than 28,000 environmental measurements in approximately 1,000 sites covering whole France, and by the IRSN national campaign data. Our study did not show any association of childhood leukemia with exposures to natural background radiation estimated nor at diagnosis nor cumulatively during childhood. However it had a good power to highlight the risks expected from current models of risk (UNSCEAR) built from studies on the observed high doses risks. If this work does not support the hypothesis that there is an association between exposure to ionizing radiation from natural sources observed and the incidence of childhood leukemia which may be directly observable at the epidemiologic level, this question remains important enough and not investigated enough to merit further complementary studies in countries where it has not been investigated
Slama, Rémy. "Environnement et fertilité masculine : étude épidémiologique de l'effet de l'exposition masculine aux rayonnements ionisants sur le délai nécessaire pour concevoir une grossesse et sur le risque de fausse-couche spontanée." Paris 11, 2002. http://www.theses.fr/2002PA11TO47.
Full textBoissière, Arnaud. "Contribution "K" à l'effet biologique des rayonnements ionisants." Phd thesis, Université Pierre et Marie Curie - Paris VI, 2004. http://tel.archives-ouvertes.fr/tel-00006928.
Full textBooks on the topic "Épidémiologie des rayonnements ionisants"
Laroche, Pierre. Terrorisme radiologique. Paris: Elsevier, 2004.
Find full textEstades, Elisabeth Remy Jacqueline. L'EXPERTISE EN PRATIQUE - Les risques liés à la vache folle et aux rayonnements ionisants. Paris: Editions L'Harmattan, 2003.
Find full textTubiana, Maurice, André Aurengo, and Dietrich Averbeck. La relation dose-effet et l'estimation des effets cancérogènes des faibles doses de rayonnements ionisants. Paris: Éditions Nucléon, 2005.
Find full textGuessab, Ali. Contribution à l'étude des effets psychophysiologiques (spécifiques) des rayonnements non-ionisants: Action des micro-ondes sur les mono-aminés biogènes dans le tissu cérébral et du comportement chez le rat blanc. Lille: A.N.R.T. Université de Lille III, 1986.
Find full text1929-, Young Jack P., and Yalow Rosalyn S. 1921-, eds. Radiation and public perception: Benefits and risks. Washington, DC: American Chemical Society, 1995.
Find full textNational Council on Radiation Protection and Measurements., ed. Risk estimates for radiation protection. Bethesda, Md: the Council, 1993.
Find full textTakeshi, Yamada, ed. Biological effects of low dose radiation: Proceedings of the International Meeting on Biological Effects of Low Dose Radiation held in Cork, Ireland on 25-26 July 1999. Amsterdam: Elsevier, 2000.
Find full textBlanc. Les Rayonnements ionisants: Détection, dosimétrie, spectrométrie. Dunod, 1997.
Find full textBourgois, Laurent, and Rodolphe Antoni. Résolutions de problèmes sur les rayonnements ionisants. EDP Sciences, 2020. http://dx.doi.org/10.1051/978-2-7598-2312-3.
Full textDuchêne, Arlette, and Jacques Joussot-Dubien. Les effets biologiques des rayonnements non ionisants. Flammarion Médecine, 2001.
Find full textBook chapters on the topic "Épidémiologie des rayonnements ionisants"
Clavere, Pierre, Annie Bonnafoux-Clavere, and Jean-Marie Bonnetblanc. "Réactions cutanées induites par les rayonnements ionisants." In Manifestations dermatologiques des maladies du système hématopoïétique et oncologie dermatologique, 318–26. Paris: Springer Paris, 2009. http://dx.doi.org/10.1007/978-2-287-72092-5_25.
Full textAntoni, Rodolphe, and Laurent Bourgois. "Interaction des rayonnements ionisants dans les tissus : évaluations du kerma et de la dose absorbée." In Ingénierie et Développement Durable, 43–148. Paris: Springer Paris, 2013. http://dx.doi.org/10.1007/978-2-8178-0311-1_2.
Full textLaurier, Dominique, Enora Cléro, Claire Demoury, Aimée Lauzon, and Jean-François Lecomte. "Chapitre 31. Rayonnements ionisants." In Environnement et santé publique, 829–49. Presses de l’EHESP, 2023. http://dx.doi.org/10.3917/ehesp.goupi.2023.01.0829.
Full textCordoliani, Yves-Sébastien, and Hervé Foehrenbach. "Effets biologiques des rayonnements ionisants." In Radioprotection en milieu médical, 55–69. Elsevier, 2014. http://dx.doi.org/10.1016/b978-2-294-73982-8.00005-0.
Full textWhaites, Eric, and Nicholas Drage. "Rayonnements ionisants, dosimétrie et radioprotection." In Radiographie et Radiologie Dentaires, 57–64. Elsevier, 2019. http://dx.doi.org/10.1016/b978-2-294-74352-8.00006-x.
Full textGauron, M.-C., and A. Poivey-Bellagamba. "7 Risques des rayonnements ionisants." In Grossesse et travail, 283–304. EDP Sciences, 2020. http://dx.doi.org/10.1051/978-2-7598-0847-2-011.
Full textGauron, M.-C., and A. Poivey-Bellagamba. "7 Risques des rayonnements ionisants." In Grossesse et travail, 283–304. EDP Sciences, 2020. http://dx.doi.org/10.1051/978-2-7598-0847-2.c011.
Full textCordoliani, Yves-Sébastien, Jean-François Chateil, and Hubert Ducou le Pointe. "Effets biologiques des rayonnements ionisants." In Guide de Radioprotection en Milieu Médical, 59–74. Elsevier, 2023. http://dx.doi.org/10.1016/b978-2-294-78210-7.00005-0.
Full textPlante, Michel, Geneviève Ostiguy, and Martine Souques. "Chapitre 30. Rayonnements non ionisants." In Environnement et santé publique, 799–827. Presses de l’EHESP, 2023. http://dx.doi.org/10.3917/ehesp.goupi.2023.01.0799.
Full text"Chapitre 6 : Détection des rayonnements ionisants." In Principes de radioprotection - Réglementation, 151–82. EDP Sciences, 2020. http://dx.doi.org/10.1051/978-2-7598-0316-3-009.
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