Relevant bibliographies by topics / Employing Aziridines

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Academic literature on the topic 'Employing Aziridines'

Author: Grafiati
Published: 6 September 2023

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Journal articles on the topic "Employing Aziridines"

1

Roy, Tony, Sachin Suresh Bhojgude, Trinadh Kaicharla, Manikandan Thangaraj, Bikash Garai, and Akkattu T. Biju. "Employing carboxylic acids in aryne multicomponent coupling triggered by aziridines/azetidines." Organic Chemistry Frontiers 3, no. 1 (2016): 71–76. http://dx.doi.org/10.1039/c5qo00328h.

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The transition-metal-free aryne multicomponent coupling (MCC) involving carboxylic acids initiated by aziridines/azetidines leading to the synthesis of N-aryl β/γ-amino alcohol derivatives has been developed.
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2

Li, Dan, Yijie Wang, Linqing Wang, Jie Wang, Pengxin Wang, Kezhou Wang, Li Lin, Dongsheng Liu, Xianxing Jiang, and Dongxu Yang. "Simple magnesium catalyst mediated γ-butyrolactams in desymmetrization of meso-aziridines." Chemical Communications 52, no. 62 (2016): 9640–43. http://dx.doi.org/10.1039/c6cc02877b.

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3

Mukherjee, Anindita, Nirnita C. Ghosal, Grigory V. Zyryanov, Adinath Majee, and Sougata Santra. "An Updated Library on the Synthesis of Aziridines." Current Green Chemistry 6, no. 3 (December 18, 2019): 226–41. http://dx.doi.org/10.2174/2213346106666191024123452.

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Aziridines are highly versatile intermediates in organic synthesis due to their easy access and their susceptibility to ring-opening by facile C-N bond cleavage. They are synthetically very important as they are valuable precursors of amino sugars, β-lactam antibiotics and alkaloids or present in various natural products that exhibit potent biological activities. The synthesis of this moiety from the easily available chemicals is desirable due to its tremendous use in the various branches of chemistry. Here, a short review has been reported on the synthesis of this scaffold employing different strategies under different greener conditions. Various methods have been developed in the presence of green catalysts and solvents.
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4

Li, Dan, Linqing Wang, Dongxu Yang, Bangzhi Zhang, and Rui Wang. "Catalytic Desymmetrization of meso-Aziridines with Benzofuran-2(3H)-Ones Employing a Simple In Situ-Generated Magnesium Catalyst." ACS Catalysis 5, no. 12 (November 18, 2015): 7432–36. http://dx.doi.org/10.1021/acscatal.5b02177.

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5

Trocha, Aleksandra, Dorota G. Piotrowska, and Iwona E. Głowacka. "Synthesis of Enantiomerically Enriched Protected 2-Amino-, 2,3-Diamino- and 2-Amino-3-Hydroxypropylphosphonates." Molecules 28, no. 3 (February 2, 2023): 1466. http://dx.doi.org/10.3390/molecules28031466.

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Simple and efficient strategies for the syntheses of enantiomerically enriched functionalized diethyl 2-amino-, 2,3-diamino- and 2-amino-3-hydroxypropylphosphonates have been developed starting from, respectively, N-protected (aziridin-2-yl)methylphosphonates, employing a regioselective aziridine ring-opening reaction with corresponding nucleophiles. Diethyl (R)- and (S)-2-(N-Boc-amino)propylphosphonates were obtained via direct regiospecific hydrogenolysis of the respective enantiomer of (R)- and (S)-N-Boc-(aziridin-2-yl)methylphosphonates. N-Boc-protected (R)- and (S)-2,3-diaminopropylphosphonates were synthesized from (R)- and (S)-N-Bn-(aziridin-2-yl)methylphosphonates via a regiospecific ring-opening reaction with neat trimethylsilyl azide and subsequent reduction of (R)- and (S)-2-(N-Boc-amino)-3-azidopropylphosphonates using triphenylphosphine. On the other hand, treatment of the corresponding (R)- and (S)-N-Bn-(aziridin-2-yl)methylphosphonates with glacial acetic acid led regiospecifically to the formation of (R)- and (S)-2-(N-Bn-amino)-3-acetoxypropylphosphonates.
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6

Smith, Amos B., and Dae-Shik Kim. "Multicomponent Linchpin Coupling of Silyl Dithianes Employing anN-Ts Aziridine as the Second Electrophile: Synthesis of (−)-Indolizidine 223AB." Organic Letters 6, no. 9 (April 2004): 1493–95. http://dx.doi.org/10.1021/ol049601b.

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7

Roy, Tony, Sachin Suresh Bhojgude, Trinadh Kaicharla, Manikandan Thangaraj, Bikash Garai, and Akkattu T. Biju. "ChemInform Abstract: Employing Carboxylic Acids in Aryne Multicomponent Coupling Triggered by Aziridines/Azetidines." ChemInform 47, no. 18 (April 2016). http://dx.doi.org/10.1002/chin.201618067.

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8

Chavan, Subhash P., Sanket A. Kawale, and Rajesh G. Gonnade. "cis‐Aziridine Synthon Based Synthetic Investigation for Tamiflu Employing Horner‐Wadsworth‐Emmons Reaction." European Journal of Organic Chemistry, June 7, 2022. http://dx.doi.org/10.1002/ejoc.202200384.

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9

Doubský, Jan, Stanislav Rádl, Josef Cinibulk, and Robert Klvaňa. "Synthesis of Fingolimod Employing Regioselective Aziridine Ring-Opening Reaction as a Key Step." Organic Process Research & Development, September 3, 2021. http://dx.doi.org/10.1021/acs.oprd.1c00248.

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