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Riry, Prihatini, Abdullah Mohamad Puad, Abdullah Tuan Abdul Rashid bin Tuan, Said Ismail, Hussin Halil, and Saleh Norihan Mohamad. "Extremely low frequency electromagnetic field generator suitable for plant in vitro studies." Research in Agricultural Engineering 63, No. 4 (December 7, 2017): 180–86. http://dx.doi.org/10.17221/47/2016-rae.
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The extremely low frequency electromagnetic field (ELF-EMF) occurs naturally from the earth and artificially as a human invention. The objectives of this study were to develop a suitable ELF-EMF generator for in vitro plants culture studies and to determine the effect of ELF-EMF exposure on in vitro tobacco (Nicotiana tabacum) growth and chlorophyll content. An ELF-EMF generator, the coGEM 1,000 was constructed using four coils of copper wires that were connected to a transformer, multimeter and rheostat. The coGEM 1,000 suitable for tissue culture plants is able to produce stable and uniform 6 and 12 mT 50Hz ELF-EMF in the four coils of the ELF-EMF generator. The tobacco in vitro plantlets were exposed to 6 and 12 mT of 50 Hz ELF-EMF for a period of 0.5, 1, 2 and 4 hours. The exposure to 12 mT ELF-EMF for an hour increased plant growth (shoot height); whereas the exposure to 6 mT Elf-EMF for an hour increased chlorophyll a, chlorophyll b and the total chlorophyll content.
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Srdjenovic, Branislava, Jasminka Mrdjanovic, Aleksandra Galovic, Nebojsa Kladar, Biljana Bozin, Vladimir Jurisic, and Gordana Bogdanovic. "Effect of ELF-EMF on antioxidant status and micronuclei in K562 cells and normal lymphocytes." Open Life Sciences 9, no. 10 (October 1, 2014): 931–40. http://dx.doi.org/10.2478/s11535-014-0335-9.
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AbstractThe effect of ELF-EMF on DNA through changes in antioxidative enzyme activities has not been sufficiently explored yet. The aim of this study was to determine ELF-EMF effect on antioxidative enzymes in cancer cell line and genotoxic potential on normal human lymphocytes. K562 cells were exposed to 50 Hz ELF-EMF (40 μT, 100 μT; 3 h, 24 h) and spectrophotometric determination of lipid peroxidation and antioxidative enzyme activities was conducted. Genotoxicity of ELF-EMF (50 Hz, 100 μT) was investigated by cytokinesis-block micronucleus assay in a normal human lymphocytes (exposure 24 h and 48 h). Results demonstrated that ELF-EMF did not alter the process of lipid peroxidation and superoxide dismutase activity. Catalase activity was increased only after application of 100 μT EMF for 24 h. Glutathione-S-transferase and -reductase activities were increased. Treatment with 100 μT ELF-EMF (24 h, 48 h) significantly reduced micronuclei incidence, while cell proliferation was significantly increased. Results indicate that 50 Hz ELF-EMF (40 μT, 100 μT) are week stressors which alone cannot generate enough ROS to induce process of lipid peroxidation in cancer cell line but strong enough to induce response of antioxidative system. Furthermore, 100 μT ELF-EMF in human lymphocytes did not exhibit genotoxic potential during 24 h and 48 h treatment, but stimulated cell proliferation.
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Prihatini, Riry, and Norihan Mohamad Saleh. "SENSITIVITY OF PIGMENT CONTENT OF BANANA AND ORCHID TISSUE CULTURE EXPOSED TO EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIEL." Indonesian Journal of Agricultural Science 17, no. 1 (January 30, 2017): 37. http://dx.doi.org/10.21082/ijas.v17n1.2016.p37-34.
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<p>Natural exposure of extremely low frequency electromagnetic field (ELF-EMF) occurs in the environment and acts as one of the abiotic factors that affect the growth and development of organisms. This study was conducted to determine the effect of ELF-EMF on the tissue cultured banana and slipper orchid chlorophyll content as one of the indicators in measuring plant photosynthetic capacity. Four days old banana (Musa sp. cv. Berangan) corm and seven days old slipper orchid (Paphiopedilum rothschildianum) cultures were exposed to 6 and 12 mT ELF-EMF generated by controllable ELF-EMF built up machine for 0.5, 1, 2 and 4 hours. After exposure, the banana and orchid cultures were incubated at 25° C for 8 and 16 weeks, respectively. The results showed that the ELF-EMF exposure had different effects on banana and slipper orchid cultures though both plant species belong to monocotyledon. The highest increase in chlorophyll content on banana was resulted by the high intensity and long duration of ELF-EMF exposure (12 mT for 4 hours), whereas on slipper orchid the modest and short duration of ELF-EMF exposure produced the most excessive chlorophyll content. Different ELF-EMF exposures (12 mT for 4 hours and 6 mT for 30 minutes) had potential to be applied on each plant to improve in vitro plant (banana and slipper orchid, respectively) growth. The increased chlorophyll and carotene/xanthophyll content on banana indicated that the banana was more tolerant to ELF-EMF exposure compared to slipper orchid. </p>
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Cichoń, Natalia, Piotr Czarny, Michał Bijak, Elżbieta Miller, Tomasz Śliwiński, Janusz Szemraj, and Joanna Saluk-Bijak. "Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/2181942.
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Nitric oxide (NO) is one of the most important signal molecules, involved in both physiological and pathological processes. As a neurotransmitter in the central nervous system, NO regulates cerebral blood flow, neurogenesis, and synaptic plasticity. The aim of our study was to investigate the effect of the extremely low-frequency electromagnetic field (ELF-EMF) on generation and metabolism of NO, as a neurotransmitter, in the rehabilitation of poststroke patients. Forty-eight patients were divided into two groups: ELF-EMF and non-ELF-EMF. Both groups underwent the same 4-week rehabilitation program. Additionally, the ELF-EMF group was exposed to an extremely low-frequency electromagnetic field of 40 Hz, 7 mT, for 15 min/day. Levels of 3-nitrotyrosine, nitrate/nitrite, and TNFαin plasma samples were measured, and NOS2 expression was determined in whole blood samples. Functional status was evaluated before and after a series of treatments, using the Activity Daily Living, Geriatric Depression Scale, and Mini-Mental State Examination. We observed that application of ELF-EMF significantly increased 3-nitrotyrosine and nitrate/nitrite levels, while expression of NOS2 was insignificantly decreased in both groups. The results also show that ELF-EMF treatments improved functional and mental status. We conclude that ELF-EMF therapy is capable of promoting recovery in poststroke patients.
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Cichon, Natalia, Ewelina Synowiec, Elzbieta Miller, Tomasz Sliwinski, Michal Ceremuga, Joanna Saluk-Bijak, and Michal Bijak. "Effect of Rehabilitation with Extremely Low Frequency Electromagnetic Field on Molecular Mechanism of Apoptosis in Post-Stroke Patients." Brain Sciences 10, no. 5 (April 30, 2020): 266. http://dx.doi.org/10.3390/brainsci10050266.
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Apoptosis in acute stroke is associated with a negative prognosis and is correlated with the severity of the neurological deficit. However, there is no evidence that indicates that, in the subacute phase of the stroke, the apoptosis process might activate neuroplasticity. Therefore, in this study, we investigated the effect of an extremely low frequency electromagnetic field (ELF-EMF) on the molecular mechanism of apoptosis, as used in the rehabilitation of post-stroke patients. Patients with moderate stroke severity (n = 48), 3–4 weeks after incident, were enrolled in the analysis and divided into ELF-EMF and non-ELF-EMF group. The rehabilitation program in both groups involves the following: kinesiotherapy—30 min; psychological therapy—15 min; and neurophysiological routines—60 min. Additionally, the ELF-EMF group was exposed to an ELF-EMF (40 Hz, 5 mT). In order to assess the apoptosis gene expression level, we measured the mRNA expression of BAX, BCL-2, CASP8, TNFα, and TP53. We found that ELF-EMF significantly increased the expression of BAX, CASP8, TNFα, and TP53, whereas the BCL-2 mRNA expression after ELF-EMF exposition remained at a comparable level in both groups. Thus, we suggest that increasing the expression of pro-apoptotic genes in post-stroke patients promotes the activation of signaling pathways involved in brain plasticity processes. However, further research is needed to clarify this process.
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Nishimura, Tsutomu, Harue Tada, and Masanori Fukushima. "Correlation between the Lunar Phase and Tail-Lifting Behavior of Lizards (Pogona vitticeps) Exposed to an Extremely Low-Frequency Electromagnetic Field." Animals 9, no. 5 (April 30, 2019): 208. http://dx.doi.org/10.3390/ani9050208.
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We previously showed that the agamid lizard Pogona vitticeps responded to an extremely low-frequency electromagnetic field (ELF-EMF; frequency: 6 and 8 Hz; peak magnetic field: 2.6 µT; peak electric field: 10 V/m) with tail-lifting behavior. In addition, the tail-lifting response to ELF-EMF disappeared when the parietal eyes of the lizards were covered by small round aluminum caps. This result suggests that the parietal eye contributes to light-dependent magnetoreception. In the present study, we set up an ELF-EMF group to evaluate the long-term effect of the ELF-EMF on lizards’ behavior and examine our hypothesis that exposure to ELF-EMFs increases the magnetic field sensitivity in lizards. We therefore include the lunar phase (full moon/new moon) and K index as environmental factors related to the geomagnetic field in the analysis. The number of tail lifts per individual per day was the response variable while calendar month, daily mean temperature, daily mean humidity, daily mean atmospheric pressure, full moon, new moon, and K index were the explanatory variables. We analyzed an ELF-EMF group and a control group separately. In a multiple linear regression analysis, the independent determinants associated with the number of tail lifts were the full moon, the temperature, February, March, April, and May in the ELF-EMF group and March, April, May, and June in the control group. The P. vitticeps in the ELF-EMF group responded to the full moon whereas those in the control group did not. In addition, in the ELF-EMF group, the number of tail lifts was higher on days when the K index was higher (P = 0.07) in the first period whereas there was no such tendency in either period in the control group. There is the possibility that the exposure to ELF-EMFs may increase magnetic-field sensitivity in lizards.
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Kim, Se Hun, Yei Heum Park, Hyunseong Lee, Sang Eun Lee, Jae Hong Park, Ki Hwa Lee, and Yong Han Kim. "The intensity of extremely low frequency electromagnetic field by target temperature of MEGAWARMERⓇ patient temperature management system." Anaesthesia, Pain & Intensive Care 25, no. 6 (December 22, 2021): 741–45. http://dx.doi.org/10.35975/apic.v25i6.1693.
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Background: Extremely low frequency electromagnetic field (ELF-EMF) emitted by electronic devices is associated with various biological effects on the human body. MEGAWARMERⓇ patient temperature management system (PTMS) is widely used for the patient temperature management in anesthesia and critical care. We investigated the intensity of ELF-EMF according to the distance and target temperature of MEGAWARMERⓇ PTMS to find the distance allowing minimized exposure to ELF-EMF.
Methodology: This study was a prospective experimental study. Target temperature was set at 31℃, 36℃ and 41℃. After setting each target temperature, the intensity of ELF-EMF was measured 300 times during 10 min at interval of 2 sec, at distances of 15, 30, and 45 cm from the MEGAWARMERⓇ PTMS, respectively. Nine measurement groups from 3 different target temperatures and 3 different distances resulted in 2700 data. Including background EMF intensity with the MEGAWARMERⓇ PTMS also turned off, total 3000 data in 10 groups were collected.
Results: At the distance of 15 cm from the MEGAWARMERⓇ PTMS, mean values of ELF-EMF were 4.6721 milligauss (mG), where 1 G is equivalent to 10⁻⁴ Tesla (T) (or 1 mG = 0.1 μT) at 31℃, 4.2852 mG at 36℃, and 3.9935 mG at 41℃. At the distance of 30 cm, mean values of ELF-EMF were 2.0948 mG at 31℃, 2.0790 mG at 36℃, and 2.0633 mG at 41℃. At the distances of 15 cm and 30 cm, the lower target temperature showed statistically significantly higher mean values of ELF-EMF (p < 0.05). In all three target temperatures, longer distance made statistically significantly lower mean value of ELF-EMF (p < 0.05).
Conclusions: The mean intensity of ELF-EMF from the MEGAWARMERⓇ Patient Temperature Management at the distance of 15 cm and 30 cm exceeded 2 mG recommended by Swedish Confederation of Professional Employees guideline.
Key words: Extremely low frequency electromagnetic field; Temperature management; Intensive care unit
Abbreviations: ELF-EMF– Extremely Low Frequency ElectroMagnetic Field; PRMS – Patient Temperature Management System; mG – milligauss
Citation: Kim SH, Park YH, Lee H, Lee SE, Park JH, Lee KH, Kim YH. The intensity of extremely low frequency electromagnetic field by target temperature of MEGAWARMERⓇ patient temperature management system. Anaesth. pain intensive care 2021;25(6):741-745;
DOI: 10.35975/apic.v25i6.1693
Received: August 11, 2021, Reviewed: September 30, 2021, Accepted: October 6, 2021
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Choi, Ju-Hye, Yu-Mi Kim, Hee-Jung Park, Myeong-Hyun Nam, and Young-Kwon Seo. "Extremely Low-Frequency Electromagnetic Fields Increase Cytokines in Human Hair Follicles through Wnt/β-Catenin Signaling." Biomedicines 10, no. 4 (April 18, 2022): 924. http://dx.doi.org/10.3390/biomedicines10040924.
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Hair loss is a chronic disorder that affects many people; however, a complete treatment has not yet been developed. Therefore, new therapeutic agents for preventing hair loss must be developed, and electromagnetic field (EMF) therapy has been proven to be a promising medical treatment in various fields, including hair loss treatment. This study evaluated the effect of extremely low-frequency electromagnetic field (ELF-EMF) intensity and exposure time by analyzing the expression of cytokines and anagen-related molecules, which influence hair activation and growth, in hair bulb spheroid (HBS) and hair follicle (HF) organ cultures. ELF-EMFs did not induce toxicity in the HBSs, as verified via the lactate dehydrogenase (LDH) assay. Moreover, an ELF-EMF intensity of 5–20 G promoted the expression of ALP, versican, β-catenin, and several cytokines (VEGF, PDGF, FGF-10, and ET-1) in HBSs. Immunohistochemical staining showed that ELF-EMF at an intensity of 5–20 G upregulated ALP and β-catenin and decreased TUNEL staining in HBS. Moreover, HFs exposed to ELF-EMF for 60 min exhibited an increase in hair length and a 1.5-fold increase in IL-4, ICAM-1, ALP, and versican mRNA expression compared to the control. Immunohistochemical staining indicated that 60 min of ELF-EMF can increase the expression of ALP and β-catenin and decreases TUNEL staining in organ cultures. Collectively, our results demonstrated that ELF-EMF exposure at a 10 G intensity for 60 min promoted hair shaft growth in HFs due to the effect of cytokines and adhesion molecules via the Wnt/β-catenin pathway. Therefore, ELF-EMF is a promising treatment for hair loss.
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Quaglino, Daniela, Miriam Capri, Luigi Zecca, Claudio Franceschi, and Ivonne P. Ronchetti. "The Effect on Rat Thymocytes of the Simultaneous In Vivo Exposure to 50-Hz Electric and Magnetic Field and to Continuous Light." Scientific World JOURNAL 4 (2004): 91–99. http://dx.doi.org/10.1100/tsw.2004.183.
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Thymus plays an important role in the immune system and can be modulated by numerous environmental factors, including electromagnetic fields (EMF). The present study has been undertaken with the aim to investigate the role of long-term exposure to extremely low frequency electric and magnetic fields (ELF-EMF) on thymocytes of rats housed in a regular dark/light cycle or under continuous light. Male Sprague-Dawley rats, 2 months old, were exposed or sham exposed for 8 months to 50-Hz sinusoidal EMF at two levels of field strength (1 kV/m, 5 μT and 5 kV/m, 100 μT, respectively). Thymus from adult animals exhibits signs of gradual atrophy mainly due to collagen deposition and fat substitution. This physiological involution may be accelerated by continuous light exposure that induces a massive death of thymocytes. The concurrent exposure to continuous light and to ELF-EMF did not change significantly the rate of mitoses compared to sham-exposed rats, whereas the amount of cell death was significantly increased, also in comparison with animals exposed to EMF in a 12-h dark-light cycle. In conclusion, long-term exposure to ELF-EMF, in animals housed under continuous light, may reinforce the alterations due to a photic stress, suggesting that,in vivo, stress and ELF-EMF exposure can act in synergy determining a more rapid involution of the thymus and might be responsible for an increased susceptibility to the potentially hazardous effects of ELF-EMF.
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Liu, Yong, Wen-bin Liu, Kai-jun Liu, Lin Ao, Julia Li Zhong, Jia Cao, and Jin-yi Liu. "Effect of 50 Hz Extremely Low-Frequency Electromagnetic Fields on the DNA Methylation and DNA Methyltransferases in Mouse Spermatocyte-Derived Cell Line GC-2." BioMed Research International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/237183.
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Previous studies have shown that the male reproductive system is one of the most sensitive organs to electromagnetic radiation. However, the biological effects and molecular mechanism are largely unclear. Our study was designed to elucidate the epigenetic effects of 50 Hz ELF-EMFin vitro. Mouse spermatocyte-derived GC-2 cell line was exposed to 50 Hz ELF-EMF (5 min on and 10 min off) at magnetic field intensity of 1 mT, 2 mT, and 3 mT with an intermittent exposure for 72 h. We found that 50 Hz ELF-EMF exposure decreased genome-wide methylation at 1 mT, but global methylation was higher at 3 mT compared with the controls. The expression of DNMT1 and DNMT3b was decreased at 1 mT, and 50 Hz ELF-EMF can increase the expression of DNMT1 and DNMT3b of GC-2 cells at 3 mT. However, 50 Hz ELF-EMF had little influence on the expression of DNMT3a. Then, we established DNA methylation and gene expression profiling and validated some genes with aberrant DNA methylation and expression at different intensity of 50 Hz ELF-EMF. These results suggest that the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF-EMF exposure.
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Sajadian, Akram, Elham Razmpoosh, Farshid Alaeddini, and Maryam Bassiri. "1Hz and 100mT Electromagnetic Field Induces Apoptosis in Breast Cancer Cells Through Up-Regulation of P38 and P21." Multidisciplinary Cancer Investigation 4, no. 1 (January 1, 2020): 23–29. http://dx.doi.org/10.30699/acadpub.mci.4.1.23.
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Introduction: Breast cancer is the most common cause of cancer-related death among women. Recently, extremely low-frequency electromagnetic field (ELF-EMF) has been proposed as a new interfering agent with future therapeutic potentials. Many studies have revealed that cellular processes such as apoptosis in breast cancer are affected by ELF-EMFs. However, more researches are needed to clarify the underlying mechanism of action for these fields. In this study, the apoptotic effect of ELF-EMF on the MC4L2 cell line was examined and the mRNA expression level of the P21 and P38 genes were further investigated. Methods: A triple-positive mouse breast cancer cell line (MC4L2) was purchased from the Genetic Resource Center (Iran). This study was performed on two groups of ELF-EMF exposure (100mT/1 Hz for 5 days, 120 min each day) and sham exposure. Cell viability and apoptosis rate of both the exposure and sham exposure groups weredetermined by flow cytometry. Alterations in the P21 and P38 mRNAs expression levelswere investigated; using real-time PCR. Results: ELF-EMF exposure induced 30% apoptosis in MC4L2 cells compared with the control group. The mRNA expression level of P38 and P21 was significantly increased after ELF-EMF exposure compared to the control group. Conclusions: ELF-EMF induces apoptosis in the MC4L2 triple-positive cell line. Furthermore, this exposure affects important gene expression involved in the cell cycle. Our data propose that ELF-EMF in a specific time, intensity, and frequency could be beneficial for breast cancer treatment. However, more studies are required to confirm our findings.
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Hosseini, Ehsan, Mahsa Farid Habibi, Shirin Babri, Gisou Mohaddes, Hajar abkhezr, and Hamed Heydari. "Maternal stress induced anxiety-like behavior exacerbated by electromagnetic fields radiation in female rats offspring." PLOS ONE 17, no. 8 (August 23, 2022): e0273206. http://dx.doi.org/10.1371/journal.pone.0273206.
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There is a disagreement on whether extremely low frequency electromagnetic fields (ELF-EMF) have a beneficial or harmful effect on anxiety-like behavior. Prenatal stress induces frequent disturbances in offspring physiology such as anxiety-like behavior extending to adulthood. This study was designed to evaluate the effects of prenatal stress and ELF-EMF exposure before and during pregnancy on anxiety-like behavior and some anxiety-related pathways in the hippocampus of female rat offspring. A total of 24 female rats 40 days of age were distributed into four groups of 6 rats each: control, Stress (rats whose mothers underwent chronic stress), EMF (rats whose mothers were exposed to electromagnetic fields) and EMF/S (rats whose mothers were simultaneously exposed to chronic stress and ELF-EMF). The rats were given elevated plus-maze and open field tests and then their brains were dissected and their hippocampus were subjected to analysis. ELISA was used to measure 24(S)-hydroxy cholesterol, corticosterone, and serotonin levels. Cryptochrome2, steroidogenic acute regulatory protein, 3B-Hydroxy steroid dehydrogenase, N-methyl-D-aspartate receptor 2(NMDAr2) and phosphorylated N-methyl-D-aspartate receptor 2(PNMDAr2) were assayed by immunoblotting. Anxiety-like behavior increased in all treatment groups at the same time EMF increased anxiety induced by maternal stress in the EMF/S group. The stress group showed decreased serotonin and increased corticosterone levels. ELF-EMF elevated the PNMDAr2/NMDAr2 ratio and 24(S)-hydroxy cholesterol compared to the control group but did not change corticosterone. EMF did not restore changes induced by stress in behavioral and molecular tests. The results of the current study, clarified that ELF-EMF can induce anxiety-like behavior which may be attributed to an increase in the PNMDAr2/NMDAr2 ratio and 24(S)-OHC in the hippocampus, and prenatal stress may contribute to anxiety via a decrease in serotonin and an increase in corticosterone in the hippocampus. We also found that anxiety-like behavior induced by maternal stress exposure, is exacerbated by electromagnetic fields radiation.
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Mshenskaya, Natalia, Yulia Sinitsyna, Ekaterina Kalyasova, Koshcheeva Valeria, Anastasia Zhirova, Irina Karpeeva, and Nikolay Ilin. "Influence of Schumann Range Electromagnetic Fields on Components of Plant Redox Metabolism in Wheat and Peas." Plants 11, no. 15 (July 27, 2022): 1955. http://dx.doi.org/10.3390/plants11151955.
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The Schumann Resonances (ScR) are Extremely Low Frequency (ELF) electromagnetic resonances in the Earth-ionosphere cavity excited by global lightning discharges. ScR are the part of electromagnetic field (EMF) of Earth. The influence of ScR on biological systems is still insufficiently understood. The purpose of the study is to characterize the possible role of the plant cell redox metabolism regulating system in the Schumann Resonances EMF perception. Activity of catalase and superoxide dismutase, their isoenzyme structure, content of malondialdehyde, composition of polar lipids in leaf extracts of wheat and pea plants treated with short-time (30 min) and long-time (18 days) ELF EMF with a frequency of 7.8 Hz, 14.3 Hz, 20.8 Hz have been investigated. Short-time exposure ELF EMF caused more pronounced bio effects than long-time exposure. Wheat catalase turned out to be the most sensitive parameter to magnetic fields. It is assumed that the change in the activity of wheat catalase after a short-term ELF EMF may be associated with the ability of this enzyme to perceive the action of a weak EMF through calcium calmodulin and/or cryptochromic signaling systems.
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Ross, Christina L., Mark J. Pettenati, Joseph Procita, Lisa Cathey, Sunil K. George, and Graca Almeida-Porada. "Evaluation of Cytotoxic and Genotoxic Effects of Extremely Low-frequency Electromagnetic Field on Mesenchymal Stromal Cells." Global Advances in Health and Medicine 7 (January 2018): 216495611877747. http://dx.doi.org/10.1177/2164956118777472.
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Background Interest in the use of extremely low-frequency (ELF) electromagnetic field (EMF) for the treatment of pain and inflammation is increasing due to the ability of this promising therapy to compete with pharmaceuticals without the adverse effects caused by drugs. However, there continues to be concerns regarding cytotoxic and genotoxic effects that may occur as a result of exposure to EMF. Objective To investigate this concern, we tested the effect of our known therapeutic 5 Hz, 0.4 milliTesla (mT) EMF on a human mesenchymal stromal cell (hMSC) line to determine whether ELF-EMF exposure would cause cytotoxic or genotoxic effects. Methods Treated samples along with controls were exposed to 5 Hz, 0.4 mT ELF-EMF for 20 min/day, 3×/week for 2 weeks and then assayed for cell viability, proliferation rates, and chromosome breaks. Results Cytogenetic analysis of the viability and proliferation rates along with analysis of morphological genome stability showed no cytotoxicity, and no chromosome breaks per karyotype analysis—therefore no genotoxicity. Conclusion Exposure to an ELF-EMF of 5 Hz, 0.4 mT for 20 min/day, 3×/week for 2 weeks does not cause cytotoxic or genotoxic effects in hMSCs.
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Li, Yingjiao, Chaoxia Sun, He Zhou, Hongji Huang, Yijie Chen, Xinle Duan, Shaokang Huang, and Jianghong Li. "Extremely Low-Frequency Electromagnetic Field Impairs the Development of Honeybee (Apis cerana)." Animals 12, no. 18 (September 14, 2022): 2420. http://dx.doi.org/10.3390/ani12182420.
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Increasing ELF-EMF pollution in the surrounding environment could impair the cognition and learning ability of honeybees, posing a threat to the honeybee population and its pollination ability. In a social honeybee colony, the numbers of adult bees rely on the successful large-scale rearing of larvae and continuous eclosion of new adult bees. However, no studies exist on the influence of ELF-EMFs on honeybee larvae. Therefore, we investigated the survival rate, body weight, and developmental duration of first instar larvae continuously subjected to ELF-EMF exposure. Moreover, the transcriptome of fifth instar larvae were sequenced for analyzing the difference in expressed genes. The results showed that ELF-EMF exposure decreases the survival rate and body weight of both white-eye pupae and newly emerged adults, extends the duration of development time and seriously interferes with the process of metamorphosis and pupation. The transcriptome sequencing showed that ELF-EMF exposure decreases the nutrient and energy metabolism and impedes the degradation of larvae tissues and rebuilding of pupae tissues in the metamorphosis process. The results provide an experimental basis and a new perspective for the protection of honeybee populations from ELF-EMF pollution.
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Karasek, Michal, and Marta Woldanska-Okonska. "Electromagnetic Fields and Human Endocrine System." Scientific World JOURNAL 4 (2004): 23–28. http://dx.doi.org/10.1100/tsw.2004.175.
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Extremely low frequency electromagnetic fields (ELF EMF) are commonly present in daily life all over the world. Moreover, EMF are used in the physiotherapy of many diseases because of their beneficial effects. There is widespread public concern that EMF may have potential consequences for human health. Although experimental animal studies indicate that EMF may influence secretion of some hormones, the data on the effects of EMF on human endocrine system are scarce. Most of the results concentrate on influence of EMF on secretion of melatonin. In this review, the data on the influence of EMF on human endocrine system are briefly presented and discussed.
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HÄNLE, M. M., H. M. BANZHAF, V. FORSBACH-BIRK, A. KIRCH, A. S. AKINLI, R. A. MASON, S. REUTER, and W. KRATZER. "Screening methods in alveolar echinococcosis: a follow-up study comparing Emc- and Emf-ELISA with Em2plus-ELISA and ultrasonography." Epidemiology and Infection 137, no. 1 (March 19, 2008): 139–44. http://dx.doi.org/10.1017/s0950268808000514.
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SUMMARYThe purpose of the present study was to identifyEchinococcus multilocularisinfection in follow-up of 95 subjects initially seropostive by Emc-ELISA or Emf-ELISA antibody assays and to compare the utility of these assays with specific Em2plus-ELISA and ultrasound screening forE. multilocularisinfection. At follow-up seven subjects were seropositive with both methods, while three were seropositive only with Emc-ELISA and 11 only with Emf-ELISA. All subjects were seronegative with Em2plus-ELISA. There were no manifestations ofE. multilocularisinfestation by ultrasonographic screening. Seropositivity on Emc-ELISA and Emf-ELISA screening tests does not appear to correlate with manifest alveolar echinococcosis identified by ultrasound. A recommendation for further follow-up of subjects found to be seropositive with Emc-ELISA and Emf-ELISA but with no sonographic evidence of disease is not justified at this time.
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Polaniak, Renata, Rafał Jakub Bułdak, Marta Karoń, Katarzyna Birkner, Michał Kukla, Krystyna Żwirska-Korczala, and Ewa Birkner. "Influence of an Extremely Low Frequency Magnetic Field (ELF-EMF) on Antioxidative Vitamin E Properties in AT478 Murine Squamous Cell Carcinoma Culture In Vitro." International Journal of Toxicology 29, no. 2 (March 2010): 221–30. http://dx.doi.org/10.1177/1091581809352011.
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This study examines the effects of vitamin E and an extremey low frequency electromagnetic field (ELF-EMF) and their combination in different time intervals of exposure of vitamin E (tocopherol) on the AT478 murine squamous cell carcinoma line. This study provides insight into the influence of correlations between ELF-EMF and vitamin E supplementation on antioxidant enzyme activity in malignant cells in vitro. Following vitamin E treatment, activity of the antioxidant enzymes is increased in an exposure-dependent manner compared with the untreated group. Application of ELF-EMF alone or with vitamin E increases both superoxide dismutase isoenzymes and glutathione peroxidase activities in comparison to the control group. The results suggest that ELF-EMF alters antioxidative activities of vitamin E in AT478 tumor cells. This study confirms the role of vitamin E in decreasing susceptibility to lipid peroxidation in AT478 tumor cells.
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Cios, Aleksandra, Martyna Ciepielak, Wanda Stankiewicz, and Łukasz Szymański. "The Influence of the Extremely Low Frequency Electromagnetic Field on Clear Cell Renal Carcinoma." International Journal of Molecular Sciences 22, no. 3 (January 29, 2021): 1342. http://dx.doi.org/10.3390/ijms22031342.
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The development of new technologies and industry is conducive to the increase in the number and variety of electromagnetic field (EMF) sources in our environment. The main sources of EMF are high-voltage lines, household appliances, audio/video devices, mobile phones, radio stations, and radar devices. In the growing use of electronic devices, scientists are increasingly interested in the effects of EMF on human health. Even though many studies on the effects of EMF have already been carried out, none of them has shown a significant effect on mammals, including humans. Moreover, it is not entirely clear how EMF influences cell behavior. The International Agency for Research on Cancer on 31 May 2011, classified PEM as a possible carcinogenic factor. This study aimed to investigate the effect of the electromagnetic field on morphological and functional changes in clear cell renal carcinoma. The research was carried out on in vitro cultures of four cell lines: HEK293, 786-O 769-P, and Caki1. The results of the research showed that the EMF of low frequency had a slight effect on the viability of cells. EMF, which induced cell arrest in the G1 phase, increased the number of early apoptotic cells and decreased the number of viable cells in the 786-O line. EMF did not affect the proliferation and viability of HEK293 cells. Extreme low-frequency EMF (ELF-EMF) also showed an inhibitory effect on the migration and metastatic properties of clear cell kidney cancer cells. Moreover, shortly after the end of ELF-EMF exposure, significant increases in ROS levels were observed in all tested cell lines. As part of the work, it was shown that low-frequency EMF shows an inhibitory effect on the proliferation of primary cancer cells, diminishing their migratory, invasive, and metastatic abilities. It also increases the apoptosis of cancer cells and the amount of reactive oxygen species. Based on the results of our research, we want to point up that the effect of ELF-EMF depends on a specific metabolic state or at a specific stage in the cell cycle of the cells under study.
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Gunes, Sevgi, Belgin Buyukakilli, Selma Yaman, Cagatay Han Turkseven, Ebru Ballı, Burak Cimen, Gulsen Bayrak, and Havva Didem Celikcan. "Effects of extremely low-frequency electromagnetic field exposure on the skeletal muscle functions in rats." Toxicology and Industrial Health 36, no. 2 (February 2020): 119–31. http://dx.doi.org/10.1177/0748233720912061.
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The aim of the present study was to systematically investigate the effects of chronic exposure to extremely low-frequency electromagnetic field (ELF-EMF) on electrophysiological, histological and biochemical properties of the diaphragm muscle in rats. Twenty-nine newly weaned (24 days old, 23–80 g) female ( n = 15) and male ( n = 14) Wistar Albino rats were used in this study. The animals were randomly divided into two groups: the control group and the electromagnetic field (EMF) group. The control group was also randomly divided into two groups: the control female group and the control male group. The EMF exposure group was also randomly divided into two groups: the ELF-EMF female group and the ELF-EMF male group. The rats in the ELF-EMF groups were exposed for 4 h daily for up to 7 months to 50 Hz frequency, 1.5 mT magnetic flux density. Under these experimental conditions, electrophysiological parameters (muscle bioelectrical activity parameters: intracellular action potential and resting membrane potential and muscle mechanical activity parameter: force–frequency relationship), biochemical parameters (Na+, K+, Cl− and Ca+2 levels in the blood serum of rats; Na+-K+ ATPase enzyme-specific activities in muscle tissue; and free radical metabolism in both muscle tissue and serum) and transmission electron microscopic morphometric parameters of the diaphragm muscle were determined. We found that chronic exposure to ELF-EMF had no significant effect on the histological structure and mechanical activity of the muscle and on the majority of muscle bioelectrical activity parameters, with the exception of some parameters of muscle bioelectrical activity. However, the changes in some bioelectrical activity parameters were relatively small and unlikely to be clinically relevant.
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Sakhaie, Mohammad Hassan, Mansoureh Soleimani, Bagher Pourheydar, Zahra Majd, Pezhman Atefimanesh, Sara Soleimani Asl, and Mehdi Mehdizadeh. "Effects of Extremely Low-Frequency Electromagnetic Fields on Neurogenesis and Cognitive Behavior in an Experimental Model of Hippocampal Injury." Behavioural Neurology 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/9194261.
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Exposure to extremely low-frequency electromagnetic fields may induce constant modulation in neuronal plasticity. In recent years, tremendous efforts have been made to design a suitable strategy for enhancing adult neurogenesis, which seems to be deterred due to brain senescence and several neurodegenerative diseases. In this study, we evaluated the effects of ELF-EMF on neurogenesis and memory, following treatment with trimethyltin chloride (TMT) as a neurotoxicant. The mice in all groups (n=56) were injected with BrdU during the experiment for seven consecutive days to label newborn cells. Spatial memory was assessed by the Morris water maze (MWM) test. By the end of the experiment, neurogenesis and neuronal differentiation were assessed in the hippocampus, using immunohistochemistry and Western blot analysis. Based on the findings, exposure to ELF-EMF enhanced spatial learning and memory in the MWM test. ELF-EMF exposure significantly enhanced the number of BrdU+ and NeuN+ cells in the dentate gyrus of adult mice (P<0.001 and P<0.05, resp.). Western blot analysis revealed significant upregulation of NeuroD2 in ELF-EMF-exposed mice compared to the TMT-treated group (P<0.05). These findings suggest that ELF-EMF might have clinical implications for the improvement of neurodegenerative processes and could help develop a novel therapeutic approach in regenerative medicine.
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Carlberg, Michael, Tarmo Koppel, Mikko Ahonen, and Lennart Hardell. "Case-Control Study on Occupational Exposure to Extremely Low-Frequency Electromagnetic Fields and the Association with Meningioma." BioMed Research International 2018 (2018): 1–6. http://dx.doi.org/10.1155/2018/5912394.
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Objective. Exposure to extremely low-frequency electromagnetic fields (ELF-EMF) was in 2002 classified as a possible human carcinogen, Group 2B, by the International Agency for Research on Cancer at WHO based on an increased risk for childhood leukemia. In case-control studies on brain tumors during 1997–2003 and 2007–2009 we assessed lifetime occupations in addition to exposure to different agents. The INTEROCC ELF-EMF Job-Exposure Matrix was used for associating occupations with ELF-EMF exposure (μT) with meningioma. Cumulative exposure (μT-years), average exposure (μT), and maximum exposed job (μT) were calculated. Results. No increased risk for meningioma was found in any category. For cumulative exposure in the highest exposure category 8.52+ μT years odds ratio (OR) = 0.9, 95% confidence interval (CI) = 0.7–1.2, and p linear trend = 0.45 were calculated. No statistically significant risks were found in different time windows. Conclusion. In conclusion occupational ELF-EMF was not associated with an increased risk for meningioma.
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Ploeger, Kristen G. "Cell Phone ELF-EMF Variation." International Journal of Science in Society 2, no. 1 (2011): 133–38. http://dx.doi.org/10.18848/1836-6236/cgp/v02i01/51519.
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Hernández-Pavón, Julio César, Modesto Sosa, Teodoro Córdova, Gloria Barbosa-Sabanero, Sergio Solorio-Meza, and Myrna Sabanero-López. "Study of Electromagnetic Fields on Cellular Systems." Acta Universitaria 19 (September 1, 2009): 65–70. http://dx.doi.org/10.15174/au.2009.103.
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In the last decades the interest to study the effect of non-ionizing radiation, such as the electromagnetic fields (EMF) on cellular systems has increased. In this article the interaction between EMF and biological systems is described. An analysis of the effect of the electromagnetic stimulation at different frequencies and intensities on cell cultures is performed. Preliminary results show that the stimulation with extremely low frequency electromagnetic fields (ELF-EMF), EMF from 3 to 30 Hz, on the cellular line of neuroblastomaSK-NSH induces cellular stress. This is reflected by a variation in the proteins expression in comparison with the group of cells no stimulated. In particular, the proteins expression shows that the ELF-EMF produce changes in the current proteins in normal or basal conditionsin the cells, that is, new proteins appear or there is evidence of an increasing in theamount of them.
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Patruno, Antonia, Erica Costantini, Alessio Ferrone, Mirko Pesce, Francesca Diomede, Oriana Trubiani, and Marcella Reale. "Short ELF-EMF Exposure Targets SIRT1/Nrf2/HO-1 Signaling in THP-1 Cells." International Journal of Molecular Sciences 21, no. 19 (October 2, 2020): 7284. http://dx.doi.org/10.3390/ijms21197284.
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Extremely low frequency electromagnetic fields (ELF-EMFs) have been known to modulate inflammatory responses by targeting signal transduction pathways and influencing cellular redox balance through the generation of oxidants and antioxidants. Here, we studied the molecular mechanism underlying the anti-oxidative effect of ELF-EMF in THP-1 cells, particularly with respect to antioxidant enzymes, such as heme oxygenase-1 (HO-1), regulated transcriptionally through nuclear factor E2-related factor 2 (Nrf2) activation. Cells treated with lipopolysaccharides (LPS) were exposed to a 50 Hz, 1 mT extremely low frequency electromagnetic fields for 1 h, 6 h and, 24 h. Our results indicate that ELF-EMF induced HO-1 mRNA and protein expression in LPS-treated THP-1 cells, with peak expression at 6 h, accompanied with a concomitant migration to the nucleus of a truncated HO-1 protein form. The immunostaining analysis further verified a nuclear enrichment of HO-1. Moreover, ELF-EMF inhibited the protein expressions of the sirtuin1 (SIRT1) and nuclear factor kappa B (NF-kB) pathways, confirming their anti-inflammatory/antioxidative role. Pretreatment with LY294002 (Akt inhibitor) and PD980559 (ERK inhibitor) inhibited LPS-induced Nrf2 nuclear translocation and HO-1 protein expression in ELF-EMF-exposed cells. Taken together, our results suggest that short ELF-EMF exposure exerts a protective role in THP-1 cells treated with an inflammatory/oxidative insult such as LPS, via the regulation of Nrf-2/HO-1 and SIRT1 /NF-kB pathways associated with intracellular glutathione (GSH) accumulation.
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Stankevych, Georgii, Yurii Kovra, and Alla Borta. "Formation of the quality of wheat grain by extremely low frequency electromagnetic field treatment." Technology audit and production reserves 4, no. 3(66) (August 30, 2022): 38–44. http://dx.doi.org/10.15587/2706-5448.2022.263484.
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The object of the study is the treatment of wheat grain with an electromagnetic field (EMF) of extremely low frequencies (ELF), the subjects of the study are the quality indicators of wheat seed grain of the Shestopalivka variety 2019 and 2020 crops grown in the Odesa region. (Ukraine). Problematic issues in the treatment of wheat grain with ELF EMF are the rationale for the duration of treatment of grain and the frequencies of EMF that improves the quality of seeds. The studies used methods of laboratory determination of seed quality indicators, calculation of statistical characteristics of the length of sprouts, and graphical methods for interpreting the results of studies. The studies substantiated the modes of treatment wheat grain with ELF EMF, which improves the quality of seeds and reduces the energy intensity of treatment. The effect of the duration of grain treatment and the frequency of EMF on the germination and characteristics of the length of seed shoots was studied. It has been established that, compared with untreated grain, the treatment of grain with an EMF with a frequency of 30 Hz, a magnetic induction of 10 mT for 6 minutes increases grain germination by 2–3 %, gives longer and 1.44–1.53 times more uniformly sprouted sprouts. Treatment within 60 min. reduces up to 9 % the germination of grain, the size of the shoots, increases their unevenness in length. The effect of seed germination activation by EMF treatment increases after 19 days of storage. Treatment of wheat grain in 2019 with ELF EMF at a frequency of 15–17 Hz with a magnetic induction of 10 mT for 6 min. changes germination within ±3 % control. The germination of the treated grain of wheat in 2020 of the crop decreases relative to the control to 13 % (with the exception of the frequency of 16.5 Hz, at which it did not change). Thus, the treatment of wheat grain with EMF makes it possible to influence the quality of seed grain. The results obtained encourage further research with a wider range of regime parameters and areas of wheat cultivation.
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Mahmoudinasab, Hamideh, and Mostafa Saadat. "Short-term Exposure to 50-Hz Electromagnetic Field and Alterations in NQO1 and NQO2 Expression in MCF-7 Cells." Open Access Macedonian Journal of Medical Sciences 4, no. 4 (September 24, 2016): 548–50. http://dx.doi.org/10.3889/oamjms.2016.102.
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AIM: Extremely low-frequency electromagnetic fields (ELF-EMFs) have some genotoxic effects and it may alter the mRNA levels of antioxidant genes. The NAD(P)H: quinone oxidoreductase-1 (NQO1) and NQO2 are ubiquitously expressed. Considering that there is no published data on the effect(s) of ELF-EMF (50-Hz) exposure and expression levels of NQO1 and NQO2 in the human MCF-7 cells, the present study was carried out.METHODS: The ELF-EMF (0.25 and 0.50 mT) exposure patterns were: 5 min field-on/5 min filed-off, 15 min field-on/15 min field-off, and 30 min field-on continuously. In all exposure conditions, total exposure time were 30 minutes. The RNA extraction was done at two times; immediately post exposure and two hours post exposure. The effect of ELF-EMF on gene expression was assessed by real-time PCR.RESULTS: The NQO1 mRNA level (at 0h) decreased in the cells exposed to 5 min field-on/5 min filed-off condition at 0.25 mT EMF when compared with the unexposed cells. The NQO2 mRNA level (at 0h and 2h) increased in the cells exposed to 5 min field-on/5 min filed-off condition at 0.50 mT EMF when compared with the unexposed cells.CONCLUSIONS: Alterations in the NQO1 and NQO2 mRNA levels seem at the "5 min field-on/5 min field-off" condition.
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Bugayets, N. A., S. V. Usatikov, I. V. Tereshchenko, N. T. Shamkova, and O. N. Bugayets. "Modification of protein products from sesame seeds by treatment of electromagnetic fields of extremely low frequencies to optimize functional properties." IOP Conference Series: Earth and Environmental Science 1052, no. 1 (July 1, 2022): 012015. http://dx.doi.org/10.1088/1755-1315/1052/1/012015.
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Abstract The aim of the study is the modification of sesame seed proteins by treatment with extremely low frequency electromagnetic fields (ELF EMF). It was found that treatment with ELF EMF with the following parameters: treatment duration T = 10 min, frequency ω = 12 Hz, current I = 9 A, increases the water and fat-holding capacity of full-fat flour.
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Gryz, Krzysztof, Jolanta Karpowicz, and Patryk Zradziński. "Complex Electromagnetic Issues Associated with the Use of Electric Vehicles in Urban Transportation." Sensors 22, no. 5 (February 22, 2022): 1719. http://dx.doi.org/10.3390/s22051719.
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The electromagnetic field (EMF) in electric vehicles (EVs) affects not only drivers, but also passengers (using EVs daily) and electronic devices inside. This article summarizes the measurement methods applicable in studies of complex EMF in EVs focused on the evaluation of characteristics of such exposure to EVs users and drivers, together with the results of investigations into the static magnetic field (SMF), the extremely low-frequency magnetic field (ELF) and radiofrequency (RF) EMF related to the use of the EVs in urban transportation. The investigated EMF components comply separately with limits provided by international labor law and guidelines regarding the evaluation of human short-term exposure; however other issues need attention—electromagnetic immunity of electronic devices and long-term human exposure. The strongest EMF was found in the vicinity of direct current (DC) charging installations—SMF up to 0.2 mT and ELF magnetic field up to 100 µT—and inside the EVs—up to 30 µT close to its internal electrical equipment. Exposure to RF EMF inside the EVs (up to a few V/m) was found and recognized to be emitted from outdoor radiocommunications systems, together with emissions from sources used inside vehicles, such as passenger mobile communication handsets and antennas of Wi-Fi routers.
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Yu Krynitskaya, A., M. V. Kharina, E. V. Petukhova, Z. A. Kanarskaya, and M. N. Meshcheryakova. "The influence of high frequency electromagnetic field on the growth of lactic acid bacteria used in the food industry." IOP Conference Series: Earth and Environmental Science 981, no. 2 (February 1, 2022): 022069. http://dx.doi.org/10.1088/1755-1315/981/2/022069.
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Abstract The objects of the study were lactic acid bacteria Lactobacillus lactis and Lactobacillus casei used in the food industry. It is proposed to use an extremely high frequency electromagnetic field (EMF EHF) with a wavelength of 4.9 mm for 5 minutes to activate the metabolism of lactic acid bacteria. The stimulating effect of EMF EHF on the growth of biomass and excretion of lactic acid during the growth was found. Physiological constants characterizing the development of microorganisms have been determined. It was found that the maximum yield from the consumed substrate Ymax increased by 40% and the maximum specific growth rate rmax by 70% when exposed to radiation, the consumption rate for maintenance ms decreased by 10% and the substrate saturation constant Ks by 23%. A change in the activity of key enzymes of metabolic pathways of lactose utilization immediately after the action of EMF of the EHF was revealed. The preservation of the achieved effect during the entire fermentation was observed. The activity of β-galactosidase and hexokinase after exposure to EMF EHF increases from 134% to 290%, depending on the strain and fermentation conditions. The increase in the activity of fumarate hydratase is 6-9%.
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Fateev, V. F., O. V. Denisenko, I. S. Silvestrov, D. S. Bobrov, M. M. Murzabekov, R. A. Davlatov, and V. P. Lopatin. "New methods and means of preparing maps for navigating geophysical fields of the Earth." Geodesy and Cartography 989, no. 11 (December 20, 2022): 21–31. http://dx.doi.org/10.22389/0016-7126-2022-989-11-21-31.
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The article deals with the matters of creating an integrated navigation system using measurements of the Earth`s gravitational and magnetic fields’ parameters (EGF and EMF). Such a system is to contain a strapdown inertial navigation system (SINS), as well as sensors for the current parameters of the EGF and EMF. Its simulation was carried out. As a result it was found out that, due to the use of information on the parameters of the EGF and EMF, an error of several hundred meters can be obtained. Based on the results of full-scale tests of the created integrated navigation system for the EGF and EMF, a real error of 900 m was obtained with a correction interval of SINS readings of 4 minutes. According to the results of modeling and testing of the mentioned system, the main tasks and ways to solve them are identified. The requirements for measurers of geophysical fields’ parameters and navigation charts are considered, a number of new navigation meters, new methods and tools for preparing navigation charts are proposed. The ways of developing relativistic geodesy and the possibility of using the gravitational-wave astronomy achievements in gravimetry are considered.
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Kalyada, Taisiya V., and V. P. Plekhanov. "TOPICALITY OF MONITORING OF INDUSTRIAL FREQUENCY MAGNETIC FIELDS OF 50 HZ IN RESIDENTIAL AND PUBLIC BUILDINGS." Hygiene and sanitation 98, no. 6 (October 28, 2019): 597–600. http://dx.doi.org/10.18821/0016-9900-2019-98-6-597-600.
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The problem of ensuring safety of electric and magnetic fields (EMF) of extremely low frequencies (ELF) is resulted from the development of the first low-frequency generators producing penetrating effect and causing negative biological outcomes. World power resources are doubling every 10 years, and ELF EMF are generated around by such sources. The number of sources on the scale of application, power and design diversity significantly exceeds those generating EMF in other frequency ranges. The population is exposed to 50 Hz ELF at work, in electric transport, in residential and public buildings, in residential areas. ELF EMF was found both to “pollute” the environment, be an environmental health risk factor, and affect negatively the health with potential long-term outcomes. Development of various methods and means of protection against the effect of ELF EMF remains relevant today. Limitation (regulation) of the effect of the factor both in terms of intensity and exposure is the most effective protection. Epidemiological studies to identify the relationship between exposure to ELF magnetic fields (MF) and carcinogenesis are on-going. A task panel group of research experts, established by WHO in 2005, conducted a routine procedure to assess health risks resulting from exposure to ELF MFs and, in particular, cancer and considered them to lack evidence. However, the significance of the data obtained was noted to be reduced due to procedural problems, potential systematic error of assessment. The problem remains unsolved. Research using various types of monitoring: social and hygienic, sanitary and epidemiological, is going on. Spatio-temporal monitoring of 50 Hz ELF MF in enclosed spaces of residential and public buildings, where a variety of equipment, devices, power supply systems, generating different MF levels, is an important area. The population is exposed to these conditions most of the day. Monitoring will allow assessing electromagnetic load at short-term and long-term exposures.
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Migault, Lucile, Ronan Garlantezec, Clément Piel, Laetitia Marchand-Martin, Sébastien Orazio, Marie Cheminat, Cécile Zaros, et al. "O1B.6 Maternal cumulative exposure to extremely low frequency electromagnetic fields, prematurity and bith weight: a pooled analysis of two birth cohorts." Occupational and Environmental Medicine 76, Suppl 1 (April 2019): A6.2—A6. http://dx.doi.org/10.1136/oem-2019-epi.17.
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BackgroundData on the effects of extremely low frequency electromagnetic fields (ELF-EMF) on pregnancy outcomes are inconclusive.ObjectivesTo study the relation between maternal cumulative exposure to ELF-EMF during pregnancy and the risk of prematurity or small for gestational age in a pooled analysis of two French birth cohorts.MethodsElfe and Epipage2 are both population-based birth cohorts initiated in 2011 and included 18 329 and 8400 births respectively. Health data and household, mother and child characteristics were obtained from medical records, by face-to-face interview at maternity, and completed during follow-up. A recently updated job-exposure-matrix (JEM) was used to assess cumulative exposure to ELF-EMF during three periods: 1) until 15, 2) until 28 and 3) until 32 weeks of gestation. Analyses were restricted to single live births in mainland France and to mothers with documented jobs (n=19,894). Differences in selection frame between the two cohorts were controlled using a propensity score weighting method. We used multiple imputation method to deal with missing data. Logistic regression models adjusted for the main potential confounders were used.ResultsAccording to the period studied, 3.2% to 4% of mothers were classified as highly exposed to ELF-EMF. An increased risk of spontaneous prematurity was observed among the most exposed groups in period 2 and period 3. Overall, no consistent association with small for gestational age was found.ConclusionThis study, with substantial statistical power provides evidence of a possible association between cumulative exposure to ELF-EMF during pregnancy and the risk of spontaneous prematurity.
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Zarrin, Farzaneh, Seyed Mohammad Mahdavi, Amir Modarresi Chahardehi, Zahra Razzaghi, and Nayebali Ahmadi. "The Effect of Time-Dependence of 10 Hz Electromagnetic Field on Spatial Learning and Memory in Rats." Journal of Lasers in Medical Sciences 13 (December 12, 2022): e64. http://dx.doi.org/10.34172/jlms.2022.64.
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Introduction: In everyday life, electrical devices are the primary sources of extremely low-frequency electromagnetic fields (ELF-EMF), and the human body may be a great conductor of these fields. We chose alpha band power, especially at 10 Hz frequency, due to its prior beneficial role in memory. The purpose was to clarify whether there is a relationship between ELF-EMF exposure and cognitive deficits in rats, clinical signs, behavioral analysis, and the impact of ELF-EMF during different times of exposure on neuroplasticity via the expression of BDNF. Methods: Forty adult male rats were selected randomly. The rats were exposed to ELF-EMF (10 Hz, 4 mT) for 7 days and 30 days, one hour daily. The expression of BDNF proteins in the hippocampus was evaluated after sacrificing animals to assess learning and memory function. The body weight of rats in the long-term exposed group differed significantly (P<0.05). The level of BDNF mRNA in the hippocampus was found by the RT-PCR method. Results: Our findings indicate that exposure to ELF-EMF affects spatial learning and memory and can improve memory, especially with long-term exposure. In addition, we discovered a significant difference in the long-term exposed group (P<0.05), where radiation for 30 days resulted in a substantial rise in BDNF levels. Conclusion: After prolonged exposure, male rats spent more time and traveled a greater percentage of their distance in the target quadrant, demonstrating that long-term exposure improves spatial memory and that 10 Hz might be safe.
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Shklyarova, A. N., E. V. Tsukanova, M. N. Starodubtseva, and I. A. Cheshik. "Lymphocyte cytoskeleton reorganization caused by a short-term action of an extremely low frequency electromagnetic field (50 Hz) on the blood in vitro." Health and Ecology Issues, no. 4 (December 28, 2020): 92–98. http://dx.doi.org/10.51523/2708-6011.2020-17-4-13.
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Objective: to detect changes in the parameters of the structure and mechanical properties of the surface layer of lymphocytes in the blood of a rat after a single action (30 min and 2 h) of an extremely low frequency electromagnetic field (ELF EMF) on the rat`s whole blood in vitro.Material and methods. We exposed the whole blood of a Wistar rat (4.5 months) to the effect of ELF EMF (50 Hz, B = 0.79 mT), generated by an experimental setup based on a Helmholtz coil. Lymphocytes were isolated from the blood using the Histopaque-1077 density gradient sedimentation method, then were placed on the surface of glass slides and fixed with glutaraldehyde, and finally were dried. We performed atomic force microscopy (AFM) using the atomic force microscope Bioscope Resolve in the PeakForce QMN mode in air.Results. On the basis of the results of the analysis of the AFM images, we classified the lymphocytes into several morphological types depending on the size of the lamellopodium. We analyzed the mechanical properties of the surface areas sized 250 nm × 250 nm for lymphocytes with the lamellopodium sized 400–1100 nm. The analysis found an rise in the elastic modulus of the lymphocyte surface after a short-term action (30 min) of ELF EMF. When the time of the ELF EMF exposure was increased up to 2 hours, the elastic (elastic modulus) and adhesive properties (the adhesion force between the AFM probe tip and cell surface) of the lymphocytes were significantly weakened.Conclusion. For the first time using the AFM method we have detected nanoscale changes in the structure and mechanical properties of the surface of the rat`s lymphocytes after a short-term action of ELF EMF (50 Hz, 0.79 mT, 30 min), which are indicative of the activation of the functions of lymphocytes as an immune system component in response to the short-term exposure of ELF EMF.
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Almarhoon, Ali, Yuan Ren, and Z. Q. Zhu. "Influence of back-EMF and current harmonics on sensorless control performance of single and dual three-phase permanent magnet synchronous machines." COMPEL: The International Journal for Computation and Mathematics in Electrical and Electronic Engineering 35, no. 2 (March 7, 2016): 744–63. http://dx.doi.org/10.1108/compel-12-2015-0441.
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Purpose – The purpose of this paper is to investigate the influence of back-EMF and current harmonics on position and speed estimation accuracy for single and dual three-phase (DTP) permanent magnet synchronous machines (PMSMs) with two fundamental-model-based sensorless control strategies which are widely utilized for AC machines, i.e. flux-linkage observer (FO) and simplified extended Kalman filter (EKF). Design/methodology/approach – The effect of distorted back-EMF is studied for sensorless vector control of single three-phase PMSM. For the influence of current harmonics, unlike the existing literature where the current harmonics are deliberately injected, in this paper, sensorless switching-table-based direct torque control (ST-DTC) strategies for DTP-PMSM which inherently suffer from non-sinusoidal stator currents in addition to the distorted back-EMF, are investigated experimentally. Findings – By employing the FO and simplified EKF-based sensorless vector control of single three-phase PMSM, it can be concluded that the rotor position estimation accuracy is less affected by the back-EMF harmonics when the simplified EKF method is utilized since it is less sensitive to such noises. When the influence of non-sinusoidal stator currents together with back-EMF harmonics is investigated for the conventional and modified ST-DTC of DTP-PMSM, it is indicated that the simplified EKF exhibits better position and speed estimation accuracy in both the conventional and modified ST-DTC strategies. In addition, its steady-state performance shows a slight superiority over that based on FO, in terms of flux and torque ripples, and THD of phase currents. For the dynamic performance, the estimated speed of simplified EKF shows less phase lag and fluctuations compared to that of FO. Originality/value – This paper introduces the influence of back-EMF and current harmonics on sensorless control performance for single and DTP PMSMs. Detailed experimental results show that the simplified EKF exhibits better rotor position and speed estimation accuracy compared to that of FO due to its higher noise-rejection ability.
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Faraji, Nafiseh, Iraj Salehi, Akram Alizadeh, Arash Pourgholaminejad, Alireza Komaki, Masoumeh Taheri Azandaryani, Reihaneh Sadeghian, and Zoleikha Golipoor. "Comparing the Effects of Long-term Exposure to Extremely Low-frequency Electromagnetic Fields With Different Values on Learning, Memory, Anxiety, and β-amyloid Deposition in Adult Rats." Basic and Clinical Neuroscience Journal 12, no. 6 (November 1, 2021): 849–60. http://dx.doi.org/10.32598/bcn.2021.1204.2.
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Introduction: Extremely Low-Frequency Electromagnetic Fields (ELF-EMFs) have gathered significant consideration for their possible pathogenicity. However, their effects on the nervous system’s functions were not fully clarified. This study aimed to assay the impact of ELF-EMFs with different intensities on memory, anxiety, antioxidant activity, β-amyloid (Aβ) deposition, and microglia population in rats. Methods: Fifty male adult rats were randomly separated into 5 groups; 4 were exposed to a flux density of 1, 100, 500, and 2000 microtesla (µT), 50 Hz frequency for one h/day for two months, and one group as a control group. The control group was without ELF-EMF stimulation. After 8 weeks, passive avoidance and Elevated Plus Maze (EPM) tests were performed to assess memory formation and anxiety-like behavior, respectively. Total free thiol groups and the index of lipid peroxidation were evaluated. Additionally, for detection of Aβ deposition and stained microglia in the brain, anti-β-amyloid and anti-Iba1 antibodies were used. Results: The step-through latency in the retention test in ELF-EMF exposure groups (100500 & 2000 µT) was significantly greater than the control group (P<0.05). Furthermore, the frequency of the entries into the open arms in ELF-EMF exposure groups (especially 2000 µT) decreased than the control group (P<0.05). No Aβ depositions were detected in the hippocampus of different groups. An increase in microglia numbers in the 100, 500, and 2000 µT groups was observed compared to the control and one µT group. Conclusion: Exposure to ELF-EMF had an anxiogenic effect on rats, promoted memory, and induced oxidative stress. No Aβ depositions were detected in the brain. Moreover, the positive impact of ELF-EMF was observed on the microglia population in the brain.
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Wei, Kai Xia. "Numerical Solution for Weight Function of Electromagnetic Flowmeter Using Finite Element Method." Applied Mechanics and Materials 444-445 (October 2013): 1360–63. http://dx.doi.org/10.4028/www.scientific.net/amm.444-445.1360.
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Weight function is related with the sensor structure of electromagnetic flowmeter (EMF). Because of complex boundary conditions, it is difficult to solve the voltage differentiation equation of EMF directly to get weight function. The finite element numerical analysis method is tried to solve the weight function for the point and large-electrode EMF in this paper. The results prove it is feasible and efficient to obtain weight function of EMA by means of finite element numerical analysis.
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Schuermann, David, and Meike Mevissen. "Manmade Electromagnetic Fields and Oxidative Stress—Biological Effects and Consequences for Health." International Journal of Molecular Sciences 22, no. 7 (April 6, 2021): 3772. http://dx.doi.org/10.3390/ijms22073772.
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Concomitant with the ever-expanding use of electrical appliances and mobile communication systems, public and occupational exposure to electromagnetic fields (EMF) in the extremely-low-frequency and radiofrequency range has become a widely debated environmental risk factor for health. Radiofrequency (RF) EMF and extremely-low-frequency (ELF) MF have been classified as possibly carcinogenic to humans (Group 2B) by the International Agency for Research on Cancer (IARC). The production of reactive oxygen species (ROS), potentially leading to cellular or systemic oxidative stress, was frequently found to be influenced by EMF exposure in animals and cells. In this review, we summarize key experimental findings on oxidative stress related to EMF exposure from animal and cell studies of the last decade. The observations are discussed in the context of molecular mechanisms and functionalities relevant to health such as neurological function, genome stability, immune response, and reproduction. Most animal and many cell studies showed increased oxidative stress caused by RF-EMF and ELF-MF. In order to estimate the risk for human health by manmade exposure, experimental studies in humans and epidemiological studies need to be considered as well.
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Jin, Hee, Kyuri Kim, Gayoung Park, Minjeong Kim, Haejune Lee, Sangbong Jeon, Juhwan Kim, Hakrim Kim, Kyungmin Lim, and Yunsil Lee. "The Protective Effects of EMF-LTE against DNA Double-Strand Break Damage In Vitro and In Vivo." International Journal of Molecular Sciences 22, no. 10 (May 12, 2021): 5134. http://dx.doi.org/10.3390/ijms22105134.
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With the rapid growth of the wireless communication industry, humans are extensively exposed to electromagnetic fields (EMF) comprised of radiofrequency (RF). The skin is considered the primary target of EMFs given its outermost location. Recent evidence suggests that extremely low frequency (ELF)-EMF can improve the efficacy of DNA repair in human cell-lines. However, the effects of EMF-RF on DNA damage remain unknown. Here, we investigated the impact of EMF-long term evolution (LTE, 1.762 GHz, 8 W/kg) irradiation on DNA double-strand break (DSB) using the murine melanoma cell line B16 and the human keratinocyte cell line HaCaT. EMF-LTE exposure alone did not affect cell viability or induce apoptosis or necrosis. In addition, DNA DSB damage, as determined by the neutral comet assay, was not induced by EMF-LTE irradiation. Of note, EMF-LTE exposure can attenuate the DNA DSB damage induced by physical and chemical DNA damaging agents (such as ionizing radiation (IR, 10 Gy) in HaCaT and B16 cells and bleomycin (BLM, 3 μM) in HaCaT cells and a human melanoma cell line MNT-1), suggesting that EMF-LTE promotes the repair of DNA DSB damage. The protective effect of EMF-LTE against DNA damage was further confirmed by attenuation of the DNA damage marker γ-H2AX after exposure to EMF-LTE in HaCaT and B16 cells. Most importantly, irradiation of EMF-LTE (1.76 GHz, 6 W/kg, 8 h/day) on mice in vivo for 4 weeks reduced the γ-H2AX level in the skin tissue, further supporting the protective effects of EMF-LTE against DNA DSB damage. Furthermore, p53, the master tumor-suppressor gene, was commonly upregulated by EMF-LTE irradiation in B16 and HaCaT cells. This finding suggests that p53 plays a role in the protective effect of EMF-LTE against DNA DSBs. Collectively, these results demonstrated that EMF-LTE might have a protective effect against DNA DSB damage in the skin, although further studies are necessary to understand its impact on human health.
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Cherenkov, Aleksander, Taras Hutsol, Igor Garasymchuk, Jurii Pancyr, Dmytro Terenov, and Vitalii Dubyna. "Analysis of Broadband Antenna Radiation Pulses." Agricultural Engineering 22, no. 1 (March 1, 2018): 15–28. http://dx.doi.org/10.1515/agriceng-2018-0002.
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AbstractElectromagnetic energy can alter metabolic and biosynthetic processes and under certain parameters of pulsed EMF it can change pulse repetition frequency, operation cycle, power, exposure, as well as it can slow down and inhibit cell growth. MW irradiation range of RNA and DNA – containing virus reduces their infectivity. Inhibition of bacterial cultures growth, changes in phagocytic activity of protein biosynthesis, ultrastructural changes in the cells when exposed to EMF EHF. It was found in experiments with micro-organisms that biological effects of EMF on microorganisms wore a resonant character. One of the basic mechanisms of inhibitory action of EHF radiation on harmful microorganisms is the role of membranes in biological reactions of microorganisms on the EMR.
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Migault, Lucile, Ronan Garlantézec, Clément Piel, Laetitia Marchand-Martin, Sébastien Orazio, Marie Cheminat, Cécile Zaros, et al. "Maternal cumulative exposure to extremely low frequency electromagnetic fields, prematurity and small for gestational age: a pooled analysis of two birth cohorts." Occupational and Environmental Medicine 77, no. 1 (December 12, 2019): 22–31. http://dx.doi.org/10.1136/oemed-2019-105785.
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BackgroundData on the effects of extremely low frequency electromagnetic fields (ELF-EMF) on pregnancy outcomes are inconclusive.ObjectiveTo study the relation between maternal cumulative exposure to ELF-EMF during pregnancy and the risk of prematurity or small for gestational age (SGA) in a pooled analysis of two French birth cohorts.MethodsElfe and Epipage2 are both population-based birth cohorts initiated in 2011 and included 18 329 and 8400 births, respectively. Health data and household, mother and child characteristics were obtained from medical records and questionnaires at maternity and during follow-up. A job exposure matrix was used to assess cumulative exposure to ELF-EMF during three periods: (1) until 15 weeks of gestation, (2) until 28 weeks of gestation and (3) until 32 weeks of gestation. Analyses were restricted to single live births in mainland France and to mothers with documented jobs (N=19 894). Adjusted logistic regression models were used.ResultsAccording to the period studied, 3.2%–4% of mothers were classified as highly exposed. Results were heterogeneous. Increased risks of prematurity were found among low exposed mothers for the three periods, and no association was observed among the most exposed (OR1=0.92 (95% CI 0.74 to 1.15); OR2=0.98 (95% CI 0.80 to 1.21); OR3=1.14 (95% CI 0.92 to 1.41)). For SGA, no association was observed with the exception of increased risk among the low exposed mothers in period 2 and the most exposed in period 3 (OR=1.25 (95% CI 1.02 to 1.53)).ConclusionSome heterogeneous associations between ELF-EMF exposure and prematurity and SGA were observed. However, due to heterogeneity (ie, their independence regarding the level of exposure), associations cannot be definitely explained by ELF-EMF exposure.
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Amyan, Armine, and Sinerik Ayrapetyan. "The Biological Effect of Extremely Low Frequency Electromagnetic Fields and Vibrations on Barley Seed Hydration and Germination." Scientific World JOURNAL 4 (2004): 55–69. http://dx.doi.org/10.1100/tsw.2004.179.
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The changes of wet and dry weights and germination of barley seed in different periods of its swelling in nontreated (control), extremely low frequency electromagnetic fields (ELF EMF) )treated, and extremely low frequency vibrations (ELFV)treated cold (4°C) and warm (20°C) distilled water (DW) were studied. The metabolic-dependent seed hydration, dry weight dissolving, germination, and water binding in seed were modulated by preliminary EMF- and ELFV-treated DW. Frequency “windows” for the effect of EMF and ELFV on seed hydration, solubility, water binding in seed, and germination were discovered. These “windows” were different for EMF and ELFV, as well as in various phases of seed swelling. It is suggested that EMF-induced water structure modification has a different biological effect on the process of seed hydration, solubility, water binding in seed, and germination compared to ELFV.
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Patenkovic, Aleksandra, Tatjana Savic, Bojan Kenig, Zorana Kurbalija-Novicic, and Marko Andjelkovic. "The impact of extremely low frequency electromagnetic field (50Hz, 0.25 mT) on fitness components and wing traits of Drosophila subobscura." Genetika 47, no. 3 (2015): 967–82. http://dx.doi.org/10.2298/gensr1503967p.
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Over the past century, man-made electromagnetic fields (EMF) have changed the natural environment, representing one of the most common and rapidly increasing environmental factors as technology advances. Numerous studies of biological effects of exposure to EMF have been performed on Drosophila during the last 30 years, showing contrasting results. In an attempt to determine whether EMF exposures might affect the development of Drosophila, the present study examines phenotypic variations through direction and range of changes in several fitness components and wing length and width, of Drosophila subobscura isofemale lines, affected by 50 Hz EMF. Embryonal and early post-embryonal stages were exposed to homogeneous sinusoidal 0.25 mT EMF of 50 Hz. The EMF exposure caused a significantly prolonged developmental time and significantly increased the wing size with the opposite direction of directional asymmetry compared to the control group. These results shows that even such a weak EMF has the potential to modulate, through developmental pathways, some of the fitness-related traits, wing size, and wing asymmetry in D. subobscura even after one generation of exposure, showing that extremely low frequency (ELF) EMFs have relevant consequences on development, adult morphology, and fitness.
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Markus, Irit, Evyatar Ohayon, Keren Constantini, Keren Geva-Kleinberger, Rawan Ibrahim, Angela Ruban, and Yftach Gepner. "The Effect of Extremely Low-Frequency Electromagnetic Fields on Inflammation and Performance-Related Indices in Trained Athletes: A Double-Blinded Crossover Study." International Journal of Molecular Sciences 24, no. 17 (August 30, 2023): 13463. http://dx.doi.org/10.3390/ijms241713463.
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Previous investigations have demonstrated the therapeutic advantages of extremely low-frequency electromagnetic fields (ELF-EMFs) in mitigating inflammation and influencing biological processes. We aimed to shed light on the effects of ELF-EMF on recovery rate following high-intensity exercise. Nine male athletes (26.7 ± 6.0 years; 69.6 ± 7.7 kg, VO2peak 57.3 ± 6.8 mL/kg/min) completed five visits in a double-blinded crossover design, performing two consecutive testing days, following a ventilatory thresholds assessment. Following 62 min of high-intensity cycling, participants lay on an ELF-EMF mattress under active (A) and non-active (NA) conditions, immediately post protocol and during the night. Physical performance and blood markers were assessed at baseline and at 60 min (60 P) and 24 h (24 H) post-protocol. The A-condition demonstrated a notable reduction in interleukin-10 (IL-10) concentrations (mean difference = −88%, p = 0.032) and maximal isometric strength of the quadriceps muscles (mean difference = ~8%, p = 0.045) compared to the NA-condition between 60 P and 24 H. In a sensitivity analysis, the A-condition revealed that younger athletes who possessed lower fat mass experienced attenuated inflammation and biochemical responses and improved physical performance. In conclusion, ELF-EMF showed no significant overall effects on performance and inflammation after intense cycling among athletes. Post-hoc analysis revealed modest benefits of ELF-MLF, suggesting a context-dependent impact. Further research with a larger sample size and multiple sessions is needed to confirm the recovery potential of ELF-EMF.
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Bugayets, Natalia, Sergey Usatikov, Lyubov Lyubimova, Igor Tereshchenko, Azamat Shantyz, and Peter Miroshnichenko. "Prediction model of microbiological and organoleptic indicators of salads during storage with the processing by extremely low frequency electromagnetic fields." BIO Web of Conferences 17 (2020): 00110. http://dx.doi.org/10.1051/bioconf/20201700110.
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The aim of the research is the scientific justification, development and implementation of physical methods for the protection of culinary products from microbiological damage. The effect of the electromagnetic field of extremely low frequency (EMF ELF) on the expiration date of vegetable salads was studied. The effective processing parameters of the EMF ELF treatment of vegetable vinaigrette postponed its expiration date, providing high quality and safety of dishes throughout the storage period.
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Karoubi, Nafiseh, Gholamreza Khamisipour, Nahid Babaei, Narges Obeidi, and Abbas Doosti. "Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD71+ and CD235a+ erythroid like progenitor." BioImpacts 14, no. 1 (August 8, 2023): 27817. http://dx.doi.org/10.34172/bi.2023.27817.
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Introduction: Ex vivo blood production is an urgent need of most countries, and creating production protocols can save the lives of many patients. Despite the recent advances in blood production in ex vivo conditions, its high-scale production is not yet possible, and requires further studies. Therefore, by transfecting fibroblast cells with miR-16, and miR-451 genes, as well as applying low frequency electromagnetic fields (ELF-EMF) treatment, we tried to increase the differentiation of these cells into CD71+ and CD235a+ erythroid like progenitors. Methods: After preparation, and cultivation of human dermal transgenic fibroblast cells, they were transfected by Plenti3-hsa-miR451, Plenti3-hsa-miR16 and Plenti3-backbone inserted into E. coli Stbl4 genome. Then, transgenic fibroblast cells were treated with 10mT ELF-EMF every day for 20 minutes for 7 days. Using a flow cytometer, the expressions of CD71, and CD235a were studied in these cells, and the expressions of genes involved in hematopoiesis were studied using the RT-PCR technique. Results: The results indicated an increase in the differentiation of fibroblast cells treated with 10mT ELF-EMF to erythroid like progenitors. Furthermore, the percentage of CD71+ and CD235a+ cells was the highest in irradiated cells encoding miR-16 and miR-451, which indicates their differentiation into erythroid like progenitors. Also, in the transgenic cells treated with ELF-EMF, an increase in the expressions of α-chain, β-chain, γ-chain and GATA1 genes was observed, which indicates the potential of these cells for hematopoiesis. However, there was no significant difference in the expression of CD34 and CD38 genes in these cell lines. Conclusion: Both ELF-EMF and upregulations of miR-16 and miR-451 lead to improved differentiation of fibroblast cells into erythroid like progenitors.
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Li, Ni, Xiong Wu, and Chun Ming Pei. "Discussion on Precautionary Policy for EMF by Power Transmission and Transformation Project." Advanced Materials Research 356-360 (October 2011): 657–65. http://dx.doi.org/10.4028/www.scientific.net/amr.356-360.657.
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Though the suggestions on health risk assessment of extremely low frequency (ELF) electric and magnetic fields (EMF) by WHO has gradually begun to spread relative effectively among the administrative departments of environmental protection in China, there are still individual media or experts calling for reducing exposure limits to the arbitrary low level in the name of precaution, and endeavoring to affect the government to make decisions or management policies on EMF, with the purpose for their own interest. It has been leading to the increasing anxiety and fear towards EMF of general public. Based on the current status of EMF issue and standard development in China, this paper analyzes the principles of precautionary policies and related precautionary measures on EMF worldwide in combination with the result of risk assessment on ELF EMF and the suggestions for standards on exposure limits by international organizations, and comprehensively considers the practical situation of power transmission and transformation projects to put forward the recommendations. The exposure limits provided in the guidelines or standards by international organizations, such as International Commission on Non-Ionizing Radiation Protection (ICNIRP) and Institute of Electrical and Electronic Engineers (IEEE), is safe enough to protect the health of general public. And for power transmission and transformation projects, the basic restrictions are the essential limits in these guidelines or standards, while the reference levels are just easier to implement in practical for guidance. The set of criteria for precautionary principle provided by European Union could be regarded as the reference for the development principle of precautionary policy, involving proportionality, non-discrimination, consistency, examination of the benefits and costs, examination of scientific developments and so on. Since in fact the EMF by power transmission and transformation projects belongs to weak risk, the core of precautionary policies lies in being no or low cost in practical, especially for new electrical equipments.
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Pawar, Madhuri G., and Reymend Encily Martin. "Effects of Exposure to Electromagnetic Fields (EMFs) on Biological Systems." Asian Journal of Biology 20, no. 6 (May 9, 2024): 21–33. http://dx.doi.org/10.9734/ajob/2024/v20i6412.
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Electromagnetic Field (EMF) is a natural phenomenon; however, anthropogenic activities have significantly shifted its equilibrium, leading to potential deleterious effects on biological systems. As technology becomes more integrated into daily life, the increased use of electronic devices has contributed to a rise in man-made EMF exposure. This exposure can affect biological systems on physiological and molecular levels, raising concerns about its potential effects on animal development, reproductive systems, and overall ecosystem health. The review explores the physiological effects of exposure to static, extremely low-frequency (ELF), and radiofrequency (RF) fields, analyzing how EMF impacts oxidative stress, reproductive physiology, cardiovascular function, brain and nervous system activity, and DNA/RNA integrity. It also acknowledges the emerging concern of EMF in aquatic environments, where underwater power supplies and extensive underwater cable networks are sources of EMF exposure that may affect marine and freshwater species. The potential effects on marine life include disruptions to migratory patterns, altered reproductive cycles, and changes in aquatic biodiversity. The review acknowledges that research on EMF has improved over time, but significant gaps and information remain. It emphasizes the need for immediate attention to address the challenges and opportunities in this field.
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Abdimuratov, Zh S., Zh D. Manbetova, M. N. Imankul, K. S. Chezhimbayeva, and A. Zh Sagyndikova. "METHODS FOR PROTECTING THE EQUIPMENT OF CELLULAR (MOBILE) CONNECTION FROM ELECTROMAGNETIC IMPACT." PHYSICO-MATHEMATICAL SERIES 335, no. 1 (February 10, 2021): 81–89. http://dx.doi.org/10.32014/2021.2224-5294.12.
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Under electromagnetic impact (EMI) of a sufficient level, temporary disruption of functioning, processing, transmission and storage of information in cellular equipment is possible. Possible problems of electromagnetic compatibility (EMC) of a mobile phone and a base station (BS) of cellular connection under the influence of electromagnetic radiation (EMR) from other sources and their negative impact on functioning are considered. The energy of the HF electromagnetic field (EMF) after passing through the protective case can affect the devices of shielded radio electronic equipment (REE), therefore, the possible negative consequences of the impact of high-energy EMF on the REE are described. Possible negative consequences under certain conditions from the influence of the skin-effect, the effects of electrostatic discharge and electromagnetic pulses on electronic devices are given. It is shown that the constructional method of protecting REE from the effects of external electromagnetic factors consists in reducing the collected and transmitted EMF energy by improving the design, placement and installation of equipment. Components of some vendors for 5G systems that are resistant to external interference are given, and the possibilities for reducing the radiation level of a cell phone are noted. The necessity of an integrated approach to solving EMC problems is substantiated, which consists in the use of structural, circuitry and structural-functional methods of EMC provision. The new 5G (Fifth Generation) standard will operate at higher operating frequencies compared to previous generations. Due to the workload of the electromagnetic spectrum at frequencies below 6 GHz, 5G networks will be based on wireless radio access systems operating at frequencies of 30–100 GHz, that is, in the lower band of the extremely high frequency range EHF (Extremely High Frequency), 30–300 GHz.