Journal articles on the topic 'Embryology – Experimental'

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1

BOĞA, Ayper, Seçil BİNOKAY, Ayşe KENDİRCİ, and Tuncay ÖZGÜNEN. "Experimental Embryology in Xenopus Laevis." Turkish Journal of Biology 21, no. 2 (January 1, 1997): 141–48. http://dx.doi.org/10.55730/1300-0152.2515.

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2

MÜller, GERD B. "Experimental Strategies in Evolutionary Embryology." American Zoologist 31, no. 4 (August 1991): 605–15. http://dx.doi.org/10.1093/icb/31.4.605.

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3

Busby, Lara, Dillan Saunders, Guillermo Serrano Nájera, and Benjamin Steventon. "Quantitative Experimental Embryology: A Modern Classical Approach." Journal of Developmental Biology 10, no. 4 (October 18, 2022): 44. http://dx.doi.org/10.3390/jdb10040044.

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Experimental Embryology is often referred to as a classical approach of developmental biology that has been to some extent replaced by the introduction of molecular biology and genetic techniques to the field. Inspired by the combination of this approach with advanced techniques to uncover core principles of neural crest development by the laboratory of Roberto Mayor, we review key quantitative examples of experimental embryology from recent work in a broad range of developmental biology questions. We propose that quantitative experimental embryology offers essential ways to explore the reaction of cells and tissues to targeted cell addition, removal, and confinement. In doing so, it is an essential methodology to uncover principles of development that remain elusive such as pattern regulation, scaling, and self-organisation.
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4

Solter, Davor. "Experimental Embryology of the Mouse.Kurt Burki." Quarterly Review of Biology 63, no. 1 (March 1988): 88–89. http://dx.doi.org/10.1086/415762.

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5

Fraser, Scott E., and Richard M. Harland. "The Molecular Metamorphosis of Experimental Embryology." Cell 100, no. 1 (January 2000): 41–55. http://dx.doi.org/10.1016/s0092-8674(00)81682-7.

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6

Hamburger, Viktor. "Introduction: Johannes Holtfreter, pioneer in experimental embryology." Developmental Dynamics 205, no. 3 (March 1996): 214–16. http://dx.doi.org/10.1002/(sici)1097-0177(199603)205:3<214::aid-aja2>3.0.co;2-l.

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7

Ribatti, Domenico, and Tiziana Annese. "Chick embryo in experimental embryology and more." Pathology - Research and Practice 245 (May 2023): 154478. http://dx.doi.org/10.1016/j.prp.2023.154478.

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8

Richardson, Michael, Roger Keynes, Paula Mabee, and Lynne Selwood. "Founding Editorial: Embryology — An Integrated Approach." Scientific World JOURNAL 1 (2001): 602–4. http://dx.doi.org/10.1100/tsw.2001.298.

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We introduce the Embryology domain of TheScientificWorld and outline the scope and aims. We argue for an interdisciplinary approach to problems in develop-mental biology. Three areas are identified as being of particular relevance to this domain: evolutionary developmental biology, teratology, and descriptive or experimental embryology.
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9

TICKLE, CHERYL. "Experimental Embryology as Applied to the Upper Limb." Journal of Hand Surgery 12, no. 3 (June 1987): 294–300. http://dx.doi.org/10.1016/0266-7681_87_90177-x.

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10

TICKLE, C. "Experimental embryology as applied to the upper limb." Journal of Hand Surgery: Journal of the British Society for Surgery of the Hand 12, no. 3 (October 1987): 294–300. http://dx.doi.org/10.1016/0266-7681(87)90177-x.

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11

Martins, José Luiz, Maurício Macedo, and Edna Frasson de Souza Montero. "Anorectal Malformation: State of the Art in Translating Experimental Research to the Bedside." European Journal of Pediatric Surgery 29, no. 04 (August 2019): 368–70. http://dx.doi.org/10.1055/s-0039-1694743.

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AbstractThe embryology of anorectal malformation (ARM) is a controversial issue. The study in humans is difficult due to the scarcity of fetuses with this anomaly. Therefore, ARM animal models, naturally obtained or induced by drugs, have been employed to understand physiopathology and possible treatments. Pigs, rabbits, rats, and mice have been employed as animal models. Additionally, many drugs have been used with this purpose: Etretinate, Ethylenethiourea, and Adriamycin. The animal more frequently used is the rat because of good reproducibility, low cost, and easy handling. Pig is a good model, but it is expensive, and difficult to handling and lodging. Concerning the drugs, Adriamycin promotes a more severe ARM compared with Ethylenethiourea. The models of ARM are of value in the understanding of the embryologic development. Nowadays, researches are aimed at identifying the molecular mechanism of this process, providing the basis for the application of tissue engineering in future experiments with ARM.
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12

Dias, Mark S., and Michael Partington. "Embryology of myelomeningocele and anencephaly." Neurosurgical Focus 16, no. 2 (February 2004): 1–16. http://dx.doi.org/10.3171/foc.2004.16.2.2.

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The authors review current views on of the embryogenesis of the neural tube defects (NTDs) myelomeningocele and anencephaly. In this context, the following four approaches to the study of NTDs are discussed: normal morphogenesis and timing of early human neural development from conception to the ascent of the conus medullaris; mechanical and molecular biology of neural tube closure derived from experimental and animal models; morphological and biomechanical features of the NTDs myelomeningocele and anencephaly; and the experimental evidence for the importance of both genetic and environmental influences on human NTDs. Although considerable insight into both normal neural tube closure and the factor(s) by which this process may be disrupted has been reported in recent years, the exact mechanism(s) by which human myelomeningoceles and anencephaly arise remain elusive.
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13

Tijani, Ahmed Adekilekun, Margaret Olutayo Alese, Adedeji Enitan Adetunji, and Kehinde Sunday Oluwadiya. "Clinical observership as an aid to learning and understanding of human embryology." Anatomy Journal of Africa 11, no. 1 (August 15, 2022): 2129–36. http://dx.doi.org/10.4314/aja.v11i1.13.

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Hands-on learning approach such as ‘Clinical observership’ is globally applicable in learning. This study evaluated clinical observership as an aid to pre-clinical medical students’ understanding of human embryology. Students were grouped into A and B; group B took calls as studentobservers in the labour ward of Ekiti State University Teaching Hospital in addition to taking regular classes in embryology while group A was the control group. Previously validated selfadministered questionnaires were used to test students’ intelligence quotient and knowledge of embryology before and after lectures and clinical observership. The short-term effect of clinical observership was tested by comparing the pre-field and post-field responses of the studentvolunteers while the long-term effect was tested by evaluating their performance in the first professional exams after the completion of pre-clinical program. The perception of group B participants on the observership program was assessed with a pre-tested questionnaire. There was no significant difference (p=0.4162) in the IQ between the control (77±1.2) and the experimental group (79±1.4). There was no significant difference (p= 0.0795) in the mean preobservation test score between the control (33±1.7) and the experimental group (38±1.7). However, a significant increase (p=0.0282) was observed in the mean post-observation test score in the experimental (29±2.4) when compared with the control (22±1.9). Although there was an increase in the mean score in the MBBS exam in the experimental group (59±2.7) when compared with the control (57±2.0), it was not statistically significant. On the perception of the method in improving learning, majority of the students were affirmative. Clinical observership enhances the learning of embryology hence we recommend its incorporation into the teaching methods of embryology in medical schools.
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14

WITKOWSKI, J. A. "The Work of Spemann: The Heritage of Experimental Embryology." Science 241, no. 4863 (July 15, 1988): 365–66. http://dx.doi.org/10.1126/science.241.4863.365.

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15

Monsoro-Burq, Anne-Helene. "Sclerotome development and morphogenesis: when experimental embryology meets genetics." International Journal of Developmental Biology 49, no. 2-3 (2005): 301–8. http://dx.doi.org/10.1387/ijdb.041953am.

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16

Schoenwolf, Gary C. "Cutting, pasting and painting: experimental embryology and neural development." Nature Reviews Neuroscience 2, no. 11 (November 2001): 763–71. http://dx.doi.org/10.1038/35097549.

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17

Weaver, Molly, and Brigid Hogan. "Powerful ideas driven by simple tools: lessons from experimental embryology." Nature Cell Biology 3, no. 7 (July 2001): E165—E167. http://dx.doi.org/10.1038/35083125.

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18

Walles, Björn. "Johri, B. M. (ed.) 1982. Experimental embryology of vascular plants." Nordic Journal of Botany 4, no. 3 (March 25, 2008): 364. http://dx.doi.org/10.1111/j.1756-1051.1984.tb01509.x.

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19

Lowe, James W. E. "Normal development and experimental embryology: Edmund Beecher Wilson and Amphioxus." Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 57 (June 2016): 44–59. http://dx.doi.org/10.1016/j.shpsc.2016.03.004.

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20

Bovolenta, Paola, and Juan-Ramón Martinez-Morales. "Genetics of congenital eye malformations: insights from chick experimental embryology." Human Genetics 138, no. 8-9 (July 6, 2018): 1001–6. http://dx.doi.org/10.1007/s00439-018-1900-5.

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21

Gurdon, J. B. "The heritage of experimental embryology: Hans Spemann and the organizer." Trends in Neurosciences 12, no. 2 (January 1989): 80. http://dx.doi.org/10.1016/0166-2236(89)90141-0.

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22

Cooke, Jonathan. "The heritage of experimental embryology: Hans Spemann and the organiser." Trends in Genetics 5 (1989): 196–97. http://dx.doi.org/10.1016/0168-9525(89)90076-0.

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23

Kuratani, S. "Insights into neural crest migration and differentiation from experimental embryology." Development 136, no. 10 (April 24, 2009): 1585–89. http://dx.doi.org/10.1242/dev.024141.

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24

Vishnyakova, Elena, Vasiliy Shirokov, and Yuriy Shirshov. "Problems of sclerotomal pain." Manual Therapy 2022, no. 2 (July 20, 2022): 49–56. http://dx.doi.org/10.54504/1684-6753-2022-2-49-56.

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25

Opiela, J., and M. Samiec. "Characterization of mesenchymal stem cells and their application in experimental embryology." Polish Journal of Veterinary Sciences 16, no. 3 (September 1, 2013): 593–99. http://dx.doi.org/10.2478/pjvs-2013-0084.

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Abstract The efficiency of somatic cell cloning (somatic cell nuclear transfer; SCNT) as well as in vitro fertilization/in vitro embryo production (IVF/IVP) in mammals stay at relatively same level for over a decade. Despite plenty of different approaches none satisfactory break-through took place. In this article, we briefly summarize the implementation of mesenchymal stem cells (MSCs) for experimental embryology. The advantages of using MSCs as nuclear donors in somatic cell cloning and in vitro embryo culture are described. The description of results obtained with these cells in mammalian embryo genomic engineering is presented.
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26

Oppenheimer, Jane. "The Heritage of Experimental Embryology. Hans Spemann and the Organizer.Viktor Hamburger." Quarterly Review of Biology 63, no. 3 (September 1988): 316–17. http://dx.doi.org/10.1086/415932.

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27

Tagarelli, A., A. Piro, P. Lagonia, and G. Tagarelli. "Hans Spemann. One Hundred Years Before the Birth of Experimental Embryology." Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C 33, no. 1 (February 2004): 28–32. http://dx.doi.org/10.1111/j.1439-0264.2004.00505.x.

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28

Sánchez-Ferrer, M. L., M. I. Acién, F. Sánchez del Campo, M. J. Mayol-Belda, and P. Acién. "Experimental contributions to the study of the embryology of the vagina." Human Reproduction 21, no. 6 (February 13, 2006): 1623–28. http://dx.doi.org/10.1093/humrep/del031.

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29

Murillo-Gonz�lez, Jorge. "Evolution of embryology: A synthesis of classical, experimental, and molecular perspectives." Clinical Anatomy 14, no. 2 (2001): 158–63. http://dx.doi.org/10.1002/1098-2353(200103)14:2<158::aid-ca1025>3.0.co;2-q.

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30

Churchill, Frederick B. "The Heritage of Experimental Embryology: Hans Spemann and the Organizer. Viktor Hamburger." Isis 80, no. 2 (June 1989): 346–47. http://dx.doi.org/10.1086/355066.

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31

Moris, Naomi, Alfonso Martinez Arias, and Benjamin Steventon. "Experimental embryology of gastrulation: pluripotent stem cells as a new model system." Current Opinion in Genetics & Development 64 (October 2020): 78–83. http://dx.doi.org/10.1016/j.gde.2020.05.031.

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32

Rinard, R. G. "Neo-Lamarckism and technique: Hans Spemann and the development of experimental embryology." Journal of the History of Biology 21, no. 1 (1988): 95–118. http://dx.doi.org/10.1007/bf00125795.

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33

Springer, Claudia, Eckhard Wolf, and Kilian Simmet. "A New Toolbox in Experimental Embryology—Alternative Model Organisms for Studying Preimplantation Development." Journal of Developmental Biology 9, no. 2 (April 2, 2021): 15. http://dx.doi.org/10.3390/jdb9020015.

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Preimplantation development is well conserved across mammalian species, but major differences in developmental kinetics, regulation of early lineage differentiation and implantation require studies in different model organisms, especially to better understand human development. Large domestic species, such as cattle and pig, resemble human development in many different aspects, i.e., the timing of zygotic genome activation, mechanisms of early lineage differentiations and the period until blastocyst formation. In this article, we give an overview of different assisted reproductive technologies, which are well established in cattle and pig and make them easily accessible to study early embryonic development. We outline the available technologies to create genetically modified models and to modulate lineage differentiation as well as recent methodological developments in genome sequencing and imaging, which form an immense toolbox for research. Finally, we compare the most recent findings in regulation of the first lineage differentiations across species and show how alternative models enhance our understanding of preimplantation development.
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34

Karasiewicz, Jolanta, and Jacek Andrzej-Modlinski. "Experimental embryology of mammals at the Jastrzebiec Institute of Genetics and Animal Breeding." International Journal of Developmental Biology 52, no. 2-3 (2008): 157–61. http://dx.doi.org/10.1387/ijdb.072316jk.

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35

Yan, Shaoyi. "Contribution of late Professor T. C. Tung to the experimental embryology of Amphioxus." Development, Growth and Differentiation 41, no. 5 (October 22, 1999): 503–22. http://dx.doi.org/10.1046/j.1440-169x.1999.00464.x.

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36

Pomelova, M. A. "N.K. Kol’tsov and experimental embryology (dedicated to the 140th anniversary of his birth)." Russian Journal of Developmental Biology 43, no. 6 (November 2012): 332–34. http://dx.doi.org/10.1134/s1062360412060057.

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37

Somer, Ljiljana, Dusan Lalosevic, and Matilda Djolai. "The contribution of pathologic diagnosis and research of the faculty members engaged in teaching histology and embryology to undergraduate medical studies." Medical review 60, no. 11-12 (2007): 523–30. http://dx.doi.org/10.2298/mpns0712523s.

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Introduction. The theoretical and practical aspects of teaching are generally defined by the curriculum, but professional experience plays an important role as well. The teaching experience of the faculty members is developed through health services, education and research. The Department of Histology and Embriology. This paper reviews the activities of the teaching staff of the Department of Histology and Embryology, pointing to the importance of pathologic diagnostics and research. It underlines the necessity of using some non-standard histologic staining methods on some tissues, organs and pathogens, as well as the results of experimental studies of the endocrine system. The experimental tumor models are used to demonstrate the interdependence of the endocrine and immune systems. Modalities and possibilities of regeneration of the digestive tract and connective tissue mucosa are explained. This paper also deals with histologic criteria used for assessment of fetal age and in the diagnosis of developmental malformations. Linear and stereologic methods, used in quantification of normal morphology, the degree of pathologic changes, and regeneration of normal structures in the courses of and after therapy, are given. The authors particularly emphasized the importance of abovementioned activities in the teaching of Histology and Embryology to undergraduate students.
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38

Sleptzova, L. A., I. V. Neklyudova, E. G. Korvin-Pavlovskaya, and O. V. Burlakova. "The Loach as an object of experimental embryological studies at the Department of Embryology." Russian Journal of Developmental Biology 31, no. 5 (September 2000): 282–86. http://dx.doi.org/10.1007/bf02758906.

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39

Sbragia, Lourenço, Rebeca Lopes Figueira, Karina Miura da Costa, and Fábio Perecim Volpe. "Gastroschisis: State of the Art in Translating Experimental Research to the Bedside." European Journal of Pediatric Surgery 29, no. 04 (August 2019): 342–51. http://dx.doi.org/10.1055/s-0039-1694746.

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AbstractThe survival rate of newborns with gastroschisis (GS) has been increasing in the past decades; however, the morbidity continues to be high, mainly related to the length of hospitalization due to disturbances of motility, absorption, and risk of intestinal infections. The development of basic research with the creation of experimental models has provided enormous advances in the understanding of the pathophysiology of the disease. These models allowed the study of the target genes involved in the embryology of the defect, the influence of the amniotic fluid, and the use of drugs and fetal therapies in an attempt to reduce the intestinal damage and to provide a rapid return of intestinal motility. Our aim was to describe the main GS models and the translational, historical impact of these research advances on the disease.
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40

Sosa, Eric A., Yuki Moriyama, Yi Ding, Nydia Tejeda-Muñoz, Gabriele Colozza, and Edward M. De Robertis. "Transcriptome analysis of regeneration during Xenopus laevis experimental twinning." International Journal of Developmental Biology 63, no. 6-7 (2019): 301–9. http://dx.doi.org/10.1387/ijdb.190006ed.

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Animal embryos have the remarkable property of self-organization. Over 125 years ago, Hans Driesch separated the two blastomeres of sea urchin embryos and obtained twins, in what was the foundation of experimental embryology. Since then, embryonic twinning has been obtained experimentally in many animals. In a recent study, we developed bisection methods that generate identical twins reliably from Xenopus blastula embryos. In the present study, we have investigated the transcriptome of regenerating half-embryos after sagittal and dorsal-ventral (D-V) bisections. Individual embryos were operated at midblastula (stage 8) with an eyelash hair and cultured until early gastrula (stage 10.5) or late gastrula (stage 12) and the transcriptome of both halves were analyzed by RNA-seq. Since many genes are activated by wound healing in Xenopus embryos, we resorted to stringent sequence analyses and identified genes up-regulated in identical twins but not in either dorsal or ventral fragments. At early gastrula, cell division-related transcripts such as histones were elevated, whereas at late gastrula, pluripotency genes (such as sox2) and germ layer determination genes (such as eomesodermin, ripply2 and activin receptor ACVRI) were identified. Among the down-regulated transcripts, sizzled, a regulator of Chordin stability, was prominent. These findings are consistent with a model in which cell division is required to heal damage, while maintaining pluripotency to allow formation of the organizer with a displacement of 90 0 from its original site. The extensive transcriptomic data presented here provides a valuable resource for data mining of gene expression during early vertebrate development.
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41

Schoenwolf, Gary C. "Contributions of the chick embryo and experimental embryology to understanding the cellular mechanisms of neurulation." International Journal of Developmental Biology 62, no. 1-2-3 (2018): 49–55. http://dx.doi.org/10.1387/ijdb.170288gs.

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42

Wourms, John P. "An Embryologist's Story The Heritage of Experimental Embryology: Hans Spemann and the Organizer Viktor Hamburger." BioScience 39, no. 5 (May 1989): 336–37. http://dx.doi.org/10.2307/1311124.

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43

McLoon, Linda K. "What Experimental Embryology Can Teach Us About the Development of the Extraocular Muscles in Anophthalmia." Archives of Ophthalmology 129, no. 8 (August 1, 2011): 1077. http://dx.doi.org/10.1001/archophthalmol.2011.187.

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44

Al-Qattan, Mohammad M. "A Review of the Genetics and Pathogenesis of Syndactyly in Humans and Experimental Animals: A 3-Step Pathway of Pathogenesis." BioMed Research International 2019 (September 15, 2019): 1–10. http://dx.doi.org/10.1155/2019/9652649.

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Embryology of normal web space creation and the genetics of syndactyly in humans and experimental animals are well described in the literature. In this review, the author offers a 3-step pathway of pathogenesis for syndactyly. The first step is initiated either by the overactivation of the WNT canonical pathway or the suppression of the Bone Morphogenetic Protein (BMP) canonical pathway. This leads to an overexpression of Fibroblast Growth Factor 8 (FGF8). The final step is the suppression of retinoic acid in the interdigital mesenchyme leading to suppression of both apoptosis and extracellular matrix (ECM) degradation, resulting in syndactyly.
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45

Ilhomovna, Kamalova Malika. "ANATOMICAL FEATURES OF THE NOSE AND NASAL CAVITY." American Journal of Medical Sciences and Pharmaceutical Research 04, no. 03 (March 1, 2022): 46–50. http://dx.doi.org/10.37547/tajmspr/volume04issue03-09.

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In this article we will review the anatomy and histology of the nasal cavity - its sections, structure and vascular and nerve supply. For experimental rhinology, the choice of a laboratory animal is very important. The scattered information on the morphology of the nose and paranasal sinuses forces the researcher to study the literature from various branches of biology (zoology, embryology, veterinary medicine, etc.) for a long time. Having analysed works describing the anatomy and morphology of the nose and paranasal sinuses in various laboratory animals.
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46

Ribatti, Domenico. "The chick embryo chorioallantoic membrane (CAM). A multifaceted experimental model." Mechanisms of Development 141 (August 2016): 70–77. http://dx.doi.org/10.1016/j.mod.2016.05.003.

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47

Marín-Padilla, Miguel. "Cephalic Axial Skeletal-Neural Dysraphic Disorders: Embryology and Pathology." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 18, no. 2 (May 1991): 153–69. http://dx.doi.org/10.1017/s0317167100031632.

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ABSTRACT:Three fundamental types of cephalic axial skeletal-neural dysrapic disorders are analyzed, including: cranioschisis aperta with encephaloschisis (anencephaly and/or exencephaly), cranioschisis occulta with occipital encephalocele, and the Chiari malformation (occipital bone hypoplasia) with compression, deformation and displacement of hindbrain, cerebellum, and medulla. Both clinical and experimental (vitamin A induced) examples of these malformations are used. The study establishes that these are not simple neurological (neural tube defects) disorders as it has been generally assumed, but complex developmental malformations affecting primarily the formation of the axial basicranium (causing skeletal defects) and the elevation of the neural folds and neurocranium (causing neural defects), and, secondarily, the topography of the facial skeleton or viscerocranium (causing oropharyngeal defects). The pathology of these skeletal, neural, and oropharyngeal defects is analyzed, their embryonic origin explored, and their developmental interrelationships discussed. The study proposes that an early paraxial mesodermal insufficiency may be the original anomaly common to all the different malformations that constitutes this heterogeneous group of dysraphic disorders. At any time during the segmental formation of the embryonic skeletal-neural axis, a simple reduction in the number of paraxial mesodermal cells produced by the Hensen node/primitive streak complex, could impair the formation of the axial skeleton as well as the elevation of the neural folds thus interfering with their closure. The final type of malformation is determined by variations of the degree, time of occurrence, and duration of the paraxial mesodermal insufficiency.
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48

Rocha, Manuel, Anastasia Beiriger, Elaine E. Kushkowski, Tetsuto Miyashita, Noor Singh, Vishruth Venkataraman, and Victoria E. Prince. "From head to tail: regionalization of the neural crest." Development 147, no. 20 (October 15, 2020): dev193888. http://dx.doi.org/10.1242/dev.193888.

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ABSTRACTThe neural crest is regionalized along the anteroposterior axis, as demonstrated by foundational lineage-tracing experiments that showed the restricted developmental potential of neural crest cells originating in the head. Here, we explore how recent studies of experimental embryology, genetic circuits and stem cell differentiation have shaped our understanding of the mechanisms that establish axial-specific populations of neural crest cells. Additionally, we evaluate how comparative, anatomical and genomic approaches have informed our current understanding of the evolution of the neural crest and its contribution to the vertebrate body.
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49

Yamashita, Hiroshi, and Masayasu Matsumoto. "Molecular pathogenesis, experimental models and new therapeutic strategies for Parkinson’s disease." Regenerative Medicine 2, no. 4 (July 2007): 447–55. http://dx.doi.org/10.2217/17460751.2.4.447.

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50

Reichenbach, Myriam, Tiongti Lim, Horst-Dieter Reichenbach, Tuna Guengoer, Felix A. Habermann, Marieke Matthiesen, Andreas Hofmann, et al. "Germ-line transmission of lentiviral PGK-EGFP integrants in transgenic cattle: new perspectives for experimental embryology." Transgenic Research 19, no. 4 (October 28, 2009): 549–56. http://dx.doi.org/10.1007/s11248-009-9333-5.

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