Relevant bibliographies by topics / Electrical stimulation

Academic literature on the topic 'Electrical stimulation'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 June 2024

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Journal articles on the topic "Electrical stimulation"

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Yuan, Yuan, Meng He, Yuan-Wen Zou, Zhong-Bing Huang, Jin-Chuan Li, and Xue-Jin Huang. "An Adjustable Electrical Stimulator for Cell Culture." Journal of Circuits, Systems and Computers 25, no. 11 (August 14, 2016): 1650146. http://dx.doi.org/10.1142/s0218126616501462.

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Electrical stimulations can promote cell growth, but most electrical stimulators could only output either voltage signals or current signals and do not output arbitrary waveforms according to need. In this paper, a wireless stimulator with adjustable stimulation signals is developed for cell culture. The original waveforms are produced by signal generating circuits. Then under the adjustment of amplification circuits, the original waveforms are converted into current stimulation signals or voltage stimulation signals. Finally, stimulation signals apply onto cells under the monitor of current measuring circuits. The stimulator can provide signals with the following characteristics: (a) required arbitrary waveforms at frequencies ranging from 0 Hz to 100[Formula: see text]kHz; (b) voltage signals at an amplitude ranging from [Formula: see text]15[Formula: see text]V to 15[Formula: see text]V with a resolution of 1[Formula: see text]mV; and (c) current signals at an amplitude ranging from [Formula: see text]1[Formula: see text]mA to 1[Formula: see text]mA with a resolution of 1[Formula: see text][Formula: see text]A when load resistance is less than 50.0[Formula: see text]k[Formula: see text]. Results of these experiments confirm that the developed instrument can provide adjustable stimulation signals for cell growth.
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Guevara, Nicolas, Eric Truy, Michel Hoen, Ruben Hermann, Clair Vandersteen, and Stéphane Gallego. "Electrical Field Interactions during Adjacent Electrode Stimulations: eABR Evaluation in Cochlear Implant Users." Journal of Clinical Medicine 12, no. 2 (January 11, 2023): 605. http://dx.doi.org/10.3390/jcm12020605.

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The present study investigates how electrically evoked Auditory Brainstem Responses (eABRs) can be used to measure local channel interactions along cochlear implant (CI) electrode arrays. eABRs were recorded from 16 experienced CI patients in response to electrical pulse trains delivered using three stimulation configurations: (1) single electrode stimulations (E11 or E13); (2) simultaneous stimulation from two electrodes separated by one (En and En+2, E11 and E13); and (3) stimulations from three consecutive electrodes (E11, E12, and E13). Stimulation level was kept constant at 70% electrical dynamic range (EDR) on the two flanking electrodes (E11 and E13) and was varied from 0 to 100% EDR on the middle electrode (E12). We hypothesized that increasing the middle electrode stimulation level would cause increasing local electrical interactions, reflected in characteristics of the evoked compound eABR. Results show that group averaged eABR wave III and V latency and amplitude were reduced when stimulation level at the middle electrode was increased, in particular when stimulation level on E12 reached 40, 70, and 100% EDR. Compound eABRs can provide a detailed individual quantification of electrical interactions occurring at specific electrodes along the CI electrode array. This approach allows a fine determination of interactions at the single electrode level potentially informing audiological decisions regarding mapping of CI systems.
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Al-Azab, Islam Mahmoud Abd-allah, Tamer I. Abo Elyazed, and Amira Mohamed El- Gendy. "TRANSCRANIAL MAGNETIC STIMULATION VERSUS ELECTRICAL VESTIBULAR STIMULATION ON BALANCE IN GERIATRICS PARKINSONIAN PATIENTS." International Journal of Physiotherapy and Research 5, no. 6 (November 11, 2017): 2464–70. http://dx.doi.org/10.16965/ijpr.2017.229.

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Fall, Magnus, and Sivert Lindström. "Electrical Stimulation." Urologic Clinics of North America 18, no. 2 (May 1991): 393–407. http://dx.doi.org/10.1016/s0094-0143(21)01005-3.

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D'Ambrosia, Robert. "Electrical Stimulation." Orthopedics 10, no. 5 (May 1987): 709. http://dx.doi.org/10.3928/0147-7447-19870501-10.

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Tanagho, Emil A. "Electrical Stimulation." Journal of the American Geriatrics Society 38, no. 3 (March 1990): 352–55. http://dx.doi.org/10.1111/j.1532-5415.1990.tb03520.x.

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Shindo, Nobuko. "Electrical Stimulation." Physiotherapy 74, no. 2 (February 1988): 74. http://dx.doi.org/10.1016/s0031-9406(10)63690-5.

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&NA;. "Electrical Stimulation." Back Letter 3, no. 8 (1989): 3. http://dx.doi.org/10.1097/00130561-198903080-00002.

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Xia, Guangbo, Beibei Song, and Jian Fang. "Electrical Stimulation Enabled via Electrospun Piezoelectric Polymeric Nanofibers for Tissue Regeneration." Research 2022 (August 3, 2022): 1–23. http://dx.doi.org/10.34133/2022/9896274.

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Electrical stimulation has demonstrated great effectiveness in the modulation of cell fate in vitro and regeneration therapy in vivo. Conventionally, the employment of electrical signal comes with the electrodes, battery, and connectors in an invasive fashion. This tedious procedure and possible infection hinder the translation of electrical stimulation technologies in regenerative therapy. Given electromechanical coupling and flexibility, piezoelectric polymers can overcome these limitations as they can serve as a self-powered stimulator via scavenging mechanical force from the organism and external stimuli wirelessly. Wireless electrical cue mediated by electrospun piezoelectric polymeric nanofibers constitutes a promising paradigm allowing the generation of localized electrical stimulation both in a noninvasive manner and at cell level. Recently, numerous studies based on electrospun piezoelectric nanofibers have been carried out in electrically regenerative therapy. In this review, brief introduction of piezoelectric polymer and electrospinning technology is elucidated first. Afterward, we highlight the activating strategies (e.g., cell traction, physiological activity, and ultrasound) of piezoelectric stimulation and the interaction of piezoelectric cue with nonelectrically/electrically excitable cells in regeneration medicine. Then, quantitative comparison of the electrical stimulation effects using various activating strategies on specific cell behavior and various cell types is outlined. Followingly, this review explores the present challenges in electrospun nanofiber-based piezoelectric stimulation for regeneration therapy and summarizes the methodologies which may be contributed to future efforts in this field for the reality of this technology in the clinical scene. In the end, a summary of this review and future perspectives toward electrospun nanofiber-based piezoelectric stimulation in tissue regeneration are elucidated.
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Walsh, Paul L., Jelena Petrovic, and R. Mark Wightman. "Distinguishing splanchnic nerve and chromaffin cell stimulation in mouse adrenal slices with fast-scan cyclic voltammetry." American Journal of Physiology-Cell Physiology 300, no. 1 (January 2011): C49—C57. http://dx.doi.org/10.1152/ajpcell.00332.2010.

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Electrical stimulation is an indispensible tool in studying electrically excitable tissues in neurobiology and neuroendocrinology. In this work, the consequences of high-intensity electrical stimulation on the release of catecholamines from adrenal gland slices were examined with fast-scan cyclic voltammetry at carbon fiber microelectrodes. A biphasic signal, consisting of a fast and slow phase, was observed when electrical stimulations typically used in tissue slices (10 Hz, 350 μA biphasic, 2.0 ms/phase pulse width) were applied to bipolar tungsten-stimulating electrodes. This signal was found to be stimulation dependent, and the slow phase of the signal was abolished when smaller (≤250 μA) and shorter (1 ms/phase) stimulations were used. The slow phase of the biphasic signal was found to be tetrodotoxin and hexamethonium independent, while the fast phase was greatly reduced using these pharmacological agents. Two different types of calcium responses were observed, where the fast phase was abolished by perfusion with a low-calcium buffer while both the fast and slow phases could be modulated when Ca2+ was completely excluded from the solution using EGTA. Perfusion with nifedipine resulted in the reduction of the slow catecholamine release to 29% of the original signal, while the fast phase was only decreased to 74% of predrug values. From these results, it was determined that high-intensity stimulations of the adrenal medulla result in depolarizing not only the splanchnic nerves, but also the chromaffin cells themselves resulting in a biphasic catecholamine release.
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Dissertations / Theses on the topic "Electrical stimulation"

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Kuhn, Andreas. "Modeling transcutaneous electrical stimulation /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17948.

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Philley, Lindsey M. "The Effects of Cold, Electrical Stimulation, and Combination Cold and Electrical Stimulation on Sensory Perception." Ohio University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1305058527.

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Woodcock, Alan. "Electrical stimulation of chronically denervated muscle." Thesis, University of Surrey, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301288.

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Hasegawa, Satoshi. "CLINICAL APPLICATIONS OF ELECTRICAL MUSCLE STIMULATION." Kyoto University, 2011. http://hdl.handle.net/2433/142294.

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Kyoto University (京都大学)
0048
新制・課程博士
博士(人間・環境学)
甲第16166号
人博第549号
新制||人||133(附属図書館)
22||人博||549(吉田南総合図書館)
28745
京都大学大学院人間・環境学研究科共生人間学専攻
(主査)教授 森谷 敏夫, 教授 津田 謹輔, 准教授 林 達也
学位規則第4条第1項該当
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Evans, Nancy C. "Determination of the most effective stimulation parameters for functional electrical stimulation." Thesis, Georgia Institute of Technology, 1989. http://hdl.handle.net/1853/20028.

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Szlavik, Robert Bruce. "In vivo electrical stimulation of motor nerves." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0032/NQ66239.pdf.

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Moen, Lars Lyse. "An Implantable Device for Electrical Nerve Stimulation." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for teknisk kybernetikk, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-26850.

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Neural stimulation is currently subject to heavy research for the control of obesity using Vagus Nerve Stimulation (VNS). The available devices for such research is however developed for human use only, causing unnecessary complications when testing in smaller animals models due to the physical size of the device. A device for use in small animal models based on commercially available components would serve as a low-cost and more optimal solution to VNS research and similar disciplines.The design of an small electrical nerve stimulator was developed based on a comprehensive literature study combined with a detailed analysis of the requirements given by the end user. The system is described using a modular architecture with explicit interfaces, supporting easy verification and reproduction of the essential parts of the system.The result is a prototype design for an implantable electrical nerve stimulator with the ability to be miniaturized into 1/4 of the size of similar stimulating systems. The design meets the requirements from the end user, but must be miniaturized and encapsulated together with a connector for the electrode pin to be ready for implementation in animals.This thesis describes a novel prototype design of an implantable stimulator with a primary use in VNS applications, compatible with the bipolar 304 leads from Cyberonics Inc. The stimulator is designed with commercially available components resulting in a low-cost and portable solution. A modular architecture describes the system with respect to specifications given by end user and limitations from a literature study.
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Grumet, Andrew Eli. "Extracellular electrical stimulation of retinal ganglion cells." Thesis, Massachusetts Institute of Technology, 1994. http://hdl.handle.net/1721.1/42559.

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Tandon, Nina. "Biomimetic electrical stimulation for cardiac tissue engineering." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/38323.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006.
Includes bibliographical references (leaves 66-69).
A major challenge of tissue engineering is directing cells to establish the physiological structure and function of the tissue being replaced. Electrical stimulation has been used to induce synchronous contractions of cultured cardiac constructs. The hypothesis adopted for this study is that functional cardiac constructs can be engineered by "mimicking" the conditions present during cardiac development, and in particular, electrical stimulation using supra-threshold signals. For this Master's Thesis research, I have compared the material properties and charge-transfer characteristics at the electrode-electrolyte interface of various biocompatible materials, including carbon, stainless steel, titanium and titanium nitride, for use as electrodes in a biomimetic system for cardiac tissue engineering. I have also designed and implemented an electrical stimulator which is capable of modulating several important parameters of electrical stimulation, including stimulus amplitude and frequency.
(cont.) In addition, I have built an experimental setup incorporating this electrical stimulator and used it for experiments with C2C12 mouse myoblast cells and neonatal rat cardiomyocytes. Lastly, I have analyzed cell morphology as well as functional performance of engineered tissue by assessing excitation thresholds and maximum capture rates.
by Nina Tandon.
S.M.
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Almashaikhi, Talal. "Electrical brain stimulation and human insular connectivity." Thesis, Lyon 1, 2013. http://www.theses.fr/2013LYO10174/document.

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Le cortex insulaire est le cinquième lobe du cerveau en charge de l'intégration de nombreuses fonctions cognitives, sous-tendues par une organisation cytoarchitectonique etune connectivité aussi riche que complexe. Ce travail vise à évaluer la connectivité fonctionnelle insulaire du cerveau humain par le biais de stimulation électrique intra-cérébrale et de potentiels évoqués cortico-corticaux (PECC) réalisés chez des patients explorés en stéréoélectroencéphalographie (SEEG) pour une épilepsie partielle réfractaire. Nous avons développé un protocole automatisé permettant destimuler successivement l’ensemble des bipoles d’enregistrement intracérébraux (deux plots contigus d’une même électrode) disponibles chez les patients explorés en SEEG. Deux sériesde 20 stimulations monophasiques d’une durée unitaire de 1 ms et d’une intentisté de 1 mA, étaient délivrés à une fréquence de 0,2 Hz au niveau de chaque bipole (105 en moyenne,produisant un total d’environ 11.000 PECC par patient). Un premier travail a consisté dans lamise au point d’une méthode fiable d’analyse statistique objective des PECC significatifs, encomplement de l’analyse visuelle, sur un échantillon de 33017 enregistrements chez trois patients. L’analyse a porté sur les quatre fenêtres temporelles post-stimulation suivantes: 10-100 ms, 100-300 ms, 300-500 ms, 500-1000 ms. La seconde partie de notre thèse a appliquéces méthodes à l’étude des connections intra-insulaires sur un échantillon de10 patients présentant au moins deux éléctrodes intra-insulaires. La dernière partie de notre travail s’est intéressé aux efférences insulaires sur un échantillon de 11 patients. L’étude des PECC apporte des éléments de connectivité fonctionnelle derésolution spatiale et temporelle inégalée, complémentaires de ceux découlant des techniquesde neuroimagerie. La gestion complexe du volume de données à gérer pour chaque patientpeut être résolu par des procédures d’analyse statistiques automatisée de sensibilité etspécificité satisfaisante. Le pattern des connections intra- et extra-insulaires révélé par cetteapproche permet une meilleure compréhension de la physiologie de l’insula chez l’Homme etdes modalités de propagations des décharges épileptiques impliquant ce lobe
The insular cortex is the fifth lobe of the brain and is in charge of the integration of many cognitive functions, underpinned by a rich cytoarchitectonic organization and a complex connectivity. Our work aims to evaluate the insular functional connectivity of the human brain using intracerebral electrical stimulation and recording of cortico-cortical evoked potentials (CCEPs) in patients investigated with stereoelectroencephalography (SEEG) for refractory partial epilepsy. We first developed an automated protocol to stimulate successively all intracerebral recorded bipoles (two contiguous leads of the same electrode) available in patients undergoing SEEG. Two sets of 20 monophasic stimulation of 1 ms duration and 1mA intensity were delivered at a frequency of 0.2 Hz at each bipole (105 on average, producing a total of about 11,000 recordings per patient). We then develop a reliable and objective statistical method to detect significant CCEPs as a complement to visual analysis, and validate this approach on a sample of 33017 recordings in three patients. The analysis was performed over four distinct post-stimulus epochs: 10-100 ms, 100-300 ms, 300-500 ms, 500-1000 ms. In the second part of our thesis, we applied these methods to the study of intrainsular connections on a sample of 10 patients with at least two intra-insular electrodes. The last part of our work used the same approach to investigate insular efferents in a sample of 11 patients. The study of CCEPs provides novel and important findings regarding the human brain functional connectivity, with unmatched spatial and temporal resolutions as compared to neuroimaging techniques. The complex management of large volume of data in each patient can be solved by automated statistical analysis procedures with satisfactory sensitivity and specificity. The pattern of connections within and outside the insula revealed by this approach provides a better understanding of the physiology of the Human insula as well as of the propagation of epileptic discharges involving this lobe
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Books on the topic "Electrical stimulation"

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Rattay, Frank. Electrical Nerve Stimulation. Vienna: Springer Vienna, 1990. http://dx.doi.org/10.1007/978-3-7091-3271-5.

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1929-, Antoni H., ed. Electrical stimulation and electropathology. Cambridge [England]: Cambridge University Press, 1992.

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Schick, Thomas, ed. Functional Electrical Stimulation in Neurorehabilitation. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-90123-3.

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Nix, W. A., and G. Vrbová, eds. Electrical Stimulation and Neuromuscular Disorders. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71337-8.

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Whittaker, Ralph Douglas Allan. Electrical stimulation in cerebral palsy. Manchester: University of Manchester, 1996.

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B, Myklebust Joel, ed. Neural stimulation. Boca Raton, Fla: CRC Press, 1985.

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Martellucci, Jacopo, ed. Electrical Stimulation for Pelvic Floor Disorders. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-06947-0.

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L, Baker Lucinda, ed. NeuroMuscular electrical stimulation: A practical guide. 4th ed. Downey, CA: Los Amigos Research & Education Institute, Inc., Rancho Los Amigos National Rehabilitation Center, 2000.

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Tapio, David. New frontiers in TENS (transcutaneous electrical nerve stimulation). Minnetonka, Minn: LecTec Corp., 1987.

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Tapio, David. New frontiers in TENS (transcutaneous electrical nerve stimulation). Minnetonka, Minn: LecTec Corp., 1987.

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Book chapters on the topic "Electrical stimulation"

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Laycock, J., and D. B. Vodušek. "Electrical Stimulation." In Therapeutic Management of Incontinence and Pelvic Pain, 85–89. London: Springer London, 2002. http://dx.doi.org/10.1007/978-1-4471-3715-3_12.

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Rossi, Peter W. "Electrical Stimulation." In Clinical Evaluation and Management of Spasticity, 93–102. Totowa, NJ: Humana Press, 2002. http://dx.doi.org/10.1007/978-1-59259-092-6_6.

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Bower, Wendy F. "Electrical Stimulation." In Pelvic Floor Re-education, 190–95. London: Springer London, 2008. http://dx.doi.org/10.1007/978-1-84628-505-9_20.

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Berghmans, Bary. "Electrical Stimulation and Magnetic Stimulation*." In Textbook of Female Urology and Urogynecology, 501–8. 5th ed. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003144236-52.

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Plonsey, Robert, and Roger C. Barr. "Functional Electrical Stimulation." In Bioelectricity, 345–83. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-1-4757-3152-1_12.

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Sigmon, Carter H., and Erik Davila-Moriel. "Electrical Nerve Stimulation." In Pain Medicine, 99–101. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-43133-8_25.

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Di Lorenzo, Carlo, Hayat Mousa, and Steven Teich. "Gastric Electrical Stimulation." In Pediatric Neurogastroenterology, 465–70. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-60761-709-9_42.

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Simon, Josh, and Bruce Simon. "Electrical Bone Stimulation." In Musculoskeletal Tissue Regeneration, 259–87. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-239-7_13.

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Kastenmeier, Andrew. "Gastric Electrical Stimulation." In Gastroparesis, 77–89. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-28929-4_6.

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Wakerley, Jon. "Electrical Stimulation Methods." In Essential Guide to Reading Biomedical Papers, 253–60. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118402184.ch28.

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Conference papers on the topic "Electrical stimulation"

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Marg, Elwin. "Non-Invasive Assessment of the Visual System by Magnetic Stimulation." In Noninvasive Assessment of the Visual System. Washington, D.C.: Optica Publishing Group, 1991. http://dx.doi.org/10.1364/navs.1991.tua3.

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Electrical stimulation of nerves can be elicited by a capacitor-discharge magnetic stimulator. The stimulation is painless and non-invasive. The principle of operation is that a magnetic field induces an electric current in the volume conductor of the tissue and triggers the depolarization of the nerve fibers. Magnetostimulation is a safe, convenient and simple method of stimulating the nervous system without pain but with less precision of localization than by electrostimulation with electrodes.
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Sun, Lifei, Sen Li, Hailong Liu, Xiang Ma, Xuyang Duan, Shui Guan, Changkai Sun, and Changsen Sun. "Appropriate Electrode Positions Improve Stimulation Efficacies in Electrical Eye Stimulations." In 2020 13th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI). IEEE, 2020. http://dx.doi.org/10.1109/cisp-bmei51763.2020.9263612.

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Laguna, Z. V., E. Cardiel, L. I. Garay, and P. R. Hernandez. "Electrical stimulator for surface nerve stimulation by using modulated pulses." In 2011 Pan American Health Care Exchanges (PAHCE 2011). IEEE, 2011. http://dx.doi.org/10.1109/pahce.2011.5871852.

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Schearer, Eric M., and Derek N. Wolf. "Functional Electrical Stimulation Capability Maps." In 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2019. http://dx.doi.org/10.1109/ner.2019.8717134.

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Kearns, K. R., and D. M. Thompson. "Macrophage response to electrical stimulation." In 2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC). IEEE, 2015. http://dx.doi.org/10.1109/nebec.2015.7117101.

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Veneva, Ivanka, Pavel Venev, Dimitar Chakarov, and Georgi Katsarov. "Device for Electrical Acupuncture Stimulation." In 2022 13th National Conference with International Participation (ELECTRONICA). IEEE, 2022. http://dx.doi.org/10.1109/electronica55578.2022.9874427.

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Alqahtani, Abdulrahman, Amr Al Abed, Nigel H. Lovell, and Socrates Dokos. "Optimizing Stimulation Strategies for Retinal Electrical Stimulation: a Modelling Study." In 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2019. http://dx.doi.org/10.1109/embc.2019.8856918.

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Pomelova, Ekaterina, Alena Popyvanova, Natalya IIyukina, Dimitri Bredikhin, Maria Koriakina, Anna N. Shestakova, and Evgeny Blagovechtchenski. "Effects of transspinal electrical stimulation estimated by transcranial magnetic stimulation." In 2022 Fourth International Conference Neurotechnologies and Neurointerfaces (CNN). IEEE, 2022. http://dx.doi.org/10.1109/cnn56452.2022.9912505.

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Gomez-Tames, Jose, and Kanata Yatsuda. "Cortical Electric Fields Differences in Transcranial Electrical Stimulation Protocols." In XXXVth URSI General Assembly and Scientific Symposium. Gent, Belgium: URSI – International Union of Radio Science, 2023. http://dx.doi.org/10.46620/ursigass.2023.0478.jsll4115.

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Jarvis, J. C. "Electrical stimulation of skeletal muscle for cardiac assistance." In IEE Colloquium on Cardiac Pacing and Electrical Stimulation of the Heart. IEE, 1996. http://dx.doi.org/10.1049/ic:19960978.

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Reports on the topic "Electrical stimulation"

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Pailino, Lia, Lihua Lou, Alberto Sesena Rubfiaro, Jin He, and Arvind Agarwal. Nanomechanical Properties of Engineered Cardiomyocytes Under Electrical Stimulation. Florida International University, October 2021. http://dx.doi.org/10.25148/mmeurs.009775.

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Engineered cardiomyocytes made of human-induced pluripotent stem cells (iPSC) present phenotypical characteristics similar to human fetal cardiomyocytes. There are different factors that are essential for engineered cardiomyocytes to be functional, one of them being that their mechanical properties must mimic those of adult cardiomyocytes. Techniques, such as electrical stimulation, have been used to improve the extracellular matrix's alignment and organization and improve the intracellular environment. Therefore, electrical stimulation could potentially be used to enhance the mechanical properties of engineered cardiac tissue. The goal of this study is to establish the effects of electrical stimulation on the elastic modulus of engineered cardiac tissue. Nanoindentation tests were performed on engineered cardiomyocyte constructs under seven days of electrical stimulation and engineered cardiomyocyte constructs without electrical stimulation. The tests were conducted using BioSoft™ In-Situ Indenter through displacement control mode with a 50 µm conospherical diamond fluid cell probe. The Hertzian fit model was used to analyze the data and obtain the elastic modulus for each construct. This study demonstrated that electrically stimulated cardiomyocytes (6.98 ± 0.04 kPa) present higher elastic modulus than cardiomyocytes without electrical stimulation (4.96 ± 0.29 kPa) at day 7 of maturation. These results confirm that electrical stimulation improves the maturation of cardiomyocytes. Through this study, an efficient nanoindentation method is demonstrated for engineered cardiomyocyte tissues, capable of capturing the nanomechanical differences between electrically stimulated and non-electrically stimulated cardiomyocytes.
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Zhang, Chengdong, Jinchao Du, Meiyi Luo, Junfang Lei, Xiaohua Fan, and Jiqin Tang. Efficacy of transcutaneous electrical acupoint stimulation on upper limb function after stroke: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2023. http://dx.doi.org/10.37766/inplasy2023.1.0036.

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Review question / Objective: To systematically evaluate the efficacy of transcutaneous electrical acupoint stimulation (TEAS) on upper limb motor dysfunction in stroke patients. P: Stroke patients. I: TEAS was performed on the basis of the control group. C: Routine rehabilitation training, which could be combined with transcutaneous electrical acupoint stimulation false stimulation, basic drug therapy or other sports therapy. O: Fugl-Meyer Assessment-Upper Extremity (FMA-UE), FMA wrist and hand part, FMA hand part, Modified Barthel Index (MBI) and Modified Ashworth Index (MAS). S: RCT. Information sources: Search PubMed, Web of Science, Cochrane Library, Embase, CNKI, Wanfang, Vip, and China Biology Medicine (CBM) Database, from the establishment of the database to December 2022.
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Nunes, Isadora, Katia Sá, Mônica Rios, Yossi Zana, and Abrahão Baptista. Non-invasive Brain Stimulation in the Management of COVID-19: Protocol for a Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2022. http://dx.doi.org/10.37766/inplasy2022.12.0033.

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Review question / Objective: What is the efficacy or effectiveness of NIBS techniques, specifically repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), transcutaneous auricular vagus nerve stimulation (taVNS), percutaneous auricular vagus nerve stimulation (paVNS), and neck vagus nerve stimulation (nVNS), in the control of outcomes associated with COVID-19 in the acute or post-COVID persistent syndrome? Eligibility criteria: Included clinical studies assessed participants with acute or persistent post-COVID-19 syndrome submitted to NIBS interventions, namely transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS), transcranial magnetic stimulation (TMS), repetitive transcranial magnetic stimulation (rTMS), theta burst (cTBS or iTBS). Studies that used peripheral and spinal cord stimulation techniques were also included. Those included vagus nerve stimulation (VNS), such as transcutaneous auricular (taVNS), percutaneous auricular (paVNS), transcranial random noise stimulation (tRNS) trans-spinal direct current stimulation (tsDCS) and other peripheral electrical stimulation (PES) techniques. Scientific communication, protocol studies, reviews and non-English papers were excluded.
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Anderson, William S., and Pawel Kudela. Biophysical Model of Cortical Network Activity and the Influence of Electrical Stimulation. Fort Belvoir, VA: Defense Technical Information Center, October 2015. http://dx.doi.org/10.21236/ad1008305.

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Huang, Jiapeng, Chunlan Yang, Kehong Zhao, Ziqi Zhao, Yin Chen, Tingting Wang, and Yun Qu. Transcutaneous Electrical Nerve Stimulation in Rodent Models of Neuropathic Pain: A Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0104.

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Hasiba-Pappas, Sophie, Lars-Peter Kamolz, Hanna Luze, Sebastian P. Nischwitz, Judith CJ Holzer-Geissler, Alexandru Christian Tuca, Theresa Rienmüller, Mathias Polz, Daniel Ziesel, and Raimund Winter. Does Electrical Stimulation Through Nerve Conduits Improve Peripheral Nerve Regeneration ? - A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2023. http://dx.doi.org/10.37766/inplasy2023.2.0057.

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Nie, Jing, He Wang, Quan-wei Jiang, Ying Zhang, Zhi-guang Zhang, and Mei Mei. Electrical stimulation for limb spasticity in children with stroke: a protocol for systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2020. http://dx.doi.org/10.37766/inplasy2020.5.0115.

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FAN, YE, JIA PENG HUANG, XU ZOU, GENG ZHEN YAO, ZHE XING MAI, and GUANG MING PAN. Effect of intravaginal electrical stimulation for overactive bladder (OAB): A protocol for meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0074.

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ADANIR, Sena, Aysegul DULGER, Serap CINAR, Elif Dilem OCAK, Ceren Sevval KARATAS, Merve OZTURK, Ersagun KEPIR, and Gokhan YAGIZ. Effects of Neuromuscular Electrical Stimulation on Muscle Architecture: A systematic review with meta-analyses. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2023. http://dx.doi.org/10.37766/inplasy2023.12.0019.

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Wang, Tian-shu, Shou-feng Wang, Wei-dong Song, Zhao-chen Tang, Wei Wei, and Guan-kai Wang. Neuromuscular electrical stimulation for cancer pain in children with osteosarcoma: A protocol of systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2020. http://dx.doi.org/10.37766/inplasy2020.6.0054.

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