Academic literature on the topic 'EIS-biosensor'

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Journal articles on the topic "EIS-biosensor"

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Li, Jiaxuan, and Jingyi Jiang. "An Electrochemical Impedance Spectroscopy Biosensor for Detecting IgG in Human Urine." Theoretical and Natural Science 78, no. 1 (2025): 111–19. https://doi.org/10.54254/2753-8818/2024.19969.

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IgG (immunoglobulin G) is the most abundant serum antibody found in blood circulation in humans and is not present in healthy human urine. The detection of IgG in urine is closely related to valuating the severity and predicting the trend of glomerulitis and other chronic kidney diseases. Electrochemical impedance spectroscopy (EIS) biosensors are highly sensitive and ideal for detecting IgG in urine. This technique uses micro-gap parallel plate electrode (PPE) as the electrode of the EIS biosensor and antifouling Y-shaped peptides as biometric element combined with PPE. The development of an
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Oliveira, A. C., and L. H. Mascaro. "Evaluation of Acetylcholinesterase Biosensor Based on Carbon Nanotube Paste in the Determination of Chlorphenvinphos." International Journal of Analytical Chemistry 2011 (2011): 1–6. http://dx.doi.org/10.1155/2011/974216.

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An amperometric biosensor for chlorphenvinphos (organophosphorus pesticide) based on carbon nanotube paste and acetylcholinesterase enzyme (CNTs-AChE biosensor) is described herein. This CNTs-AChE biosensor was characterized by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS). The SEM result shows the presence of CNTs and small lumps, due to the enzyme AChE, which has a type of cauliflower formation. From EIS analysis is possible to observe increasedRtcfor CNTs-AChE biosensor when compared to the carbon nanotube paste electrode for the reaction [Fe(CN)6]4−/3−
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Elnagar, Noha, Nada Elgiddawy, Waleed M. A. El Rouby, Ahmed A. Farghali, and Hafsa Korri-Youssoufi. "Impedimetric Detection of Cancer Markers Based on Nanofiber Copolymers." Biosensors 14, no. 2 (2024): 77. http://dx.doi.org/10.3390/bios14020077.

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The sensitive determination of folate receptors (FRs) in the early stages of cancer is of great significance for controlling the progression of cancerous cells. Many folic acid (FA)-based electrochemical biosensors have been utilized to detect FRs with promising performances, but most were complicated, non-reproducible, non-biocompatible, and time and cost consuming. Here, we developed an environmentally friendly and sensitive biosensor for FR detection. We proposed an electrochemical impedimetric biosensor formed by nanofibers (NFs) of bio-copolymers prepared by electrospinning. The biosensor
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Manickam, Arun, Aaron Chevalier, Mark McDermott, Andrew D. Ellington, and Arjang Hassibi. "A CMOS Electrochemical Impedance Spectroscopy (EIS) Biosensor Array." IEEE Transactions on Biomedical Circuits and Systems 4, no. 6 (2010): 379–90. http://dx.doi.org/10.1109/tbcas.2010.2081669.

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Le, Hien T. Ngoc, and Sungbo Cho. "Sensitive Electrochemical Detection of Phosphorylated-Tau Threonine 231 in Human Serum Using Interdigitated Wave-Shaped Electrode." Biomedicines 10, no. 1 (2021): 10. http://dx.doi.org/10.3390/biomedicines10010010.

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The development of an electrochemical biosensor for the detection of phosphorylated-tau threonine 231 (p-tau231), a biomarker of Alzheimer’s disease (AD), has yet to be achieved. Therefore, in this study, we developed a simple, small size, cheap, and sensitive electrochemical biosensor based on an interdigitated wave-shaped electrode via an activated self-assembled monolayer to preserve a specific anti–p-tau231 antibody (IWE/SAM/EDC-NHS/anti–p-tau231). Detection of p-tau231 in human serum (HS) using the biosensor was undertaken using electrochemical impedance spectroscopy (EIS). The change in
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Zhou, Yaoyu, Lin Tang, Xia Xie, et al. "Sensitive impedimetric biosensor based on duplex-like DNA scaffolds and ordered mesoporous carbon nitride for silver(i) ion detection." Analyst 139, no. 24 (2014): 6529–35. http://dx.doi.org/10.1039/c4an01607f.

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Gasparyan, L. F., I. A. Mazo, V. V. Simonyan, and F. V. Gasparyan. "EIS Biosensor for Detection of Low Concentration DNA Molecules." Journal of Contemporary Physics (Armenian Academy of Sciences) 55, no. 1 (2020): 101–9. http://dx.doi.org/10.3103/s1068337220010144.

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Shivabalan, Arun Prabha, Filipas Ambrulevicius, Martynas Talaikis, Vaidas Pudzaitis, Gediminas Niaura, and Gintaras Valincius. "Effect of pH on Electrochemical Impedance Response of Tethered Bilayer Lipid Membranes: Implications for Quantitative Biosensing." Chemosensors 11, no. 8 (2023): 450. http://dx.doi.org/10.3390/chemosensors11080450.

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Tethered bilayer lipid membranes (tBLMs) are increasingly used in biosensor applications where electrochemical impedance spectroscopy (EIS) is the method of choice for amplifying and recording the activity of membrane-damaging agents such as pore-forming toxins or disrupting peptides. While the activity of these biological agents may depend on the pH of the analytes, there is increasing evidence that the sensitivity of tethered bilayer sensors depends on the pH of the solutions. In our study, we addressed the question of what are the fundamental reasons for the variability of the EIS signal of
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Li, Jing, Byung Kun Kim, Kang-Kyun Wang, et al. "Sensing Estrogen with Electrochemical Impedance Spectroscopy." Journal of Analytical Methods in Chemistry 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/9081375.

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This study demonstrates the application feasibility of electrochemical impedance spectroscopy (EIS) in measuring estrogen (17β-estradiol) in gas phase. The present biosensor gives a linear response (R2=0.999) for 17β-estradiol vapor concentration from 3.7 ng/L to 3.7 × 10−4 ng/L with a limit of detection (3.7 × 10−4 ng/L). The results show that the fabricated biosensor demonstrates better detection limit of 17β-estradiol in gas phase than the previous report with GC-MS method. This estrogen biosensor has many potential applications for on-site detection of a variety of endocrine disrupting com
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Hozhabri, Rira, and Anastasia Elias. "Development of a Portable Electrochemical Biosensor for Rapid Diclofenac Detection in Clinical and Environmental Samples." ECS Meeting Abstracts MA2025-01, no. 61 (2025): 3141. https://doi.org/10.1149/ma2025-01613141mtgabs.

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Diclofenac, a widely used non-steroidal anti-inflammatory drug (NSAID), poses growing concerns in environmental contexts due to its potential toxicity and persistence. Accurate, real-time monitoring of diclofenac levels in both biological samples and water sources is essential to ensure therapeutic safety and reduce environmental impact. However, conventional methods such as high-performance liquid chromatography (HPLC) and gas chromatography (GC) are limited by their complexity, high cost, and lack of portability for on-site testing. To address this need, we are developing a portable electroc
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Dissertations / Theses on the topic "EIS-biosensor"

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Taing, Meng-Houit. "Characterisation and Fabrication of a Multiarray Electrolyte-Insulator-Semiconductor Biosensor." Thesis, Griffith University, 2009. http://hdl.handle.net/10072/365195.

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Label free detection methods are preferred in biological sensing applications due to their convenience, low reagent usage, and minimal equipment dependence. EIS (Electrolyte-Insulator-Semiconductor) is a type of biosensor that achieves this through the sensing of the intrinsic charges present within a biological entity such as a cell or DNA. The charge generates a field which modulates the width of the depletion region within the semiconductor and can be detected using capacitance measurements. To enable the system to be more functional, a chip containing an array of biosensors allows the dete
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Wen, Xuejin. "Design, Fabrication, and Characterization of Field-Effect and Impedance Based Biosensors." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1308312352.

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CAPALDO, PIETRO. "Capacitance immunosensors for the early detection of circulating cancer biomarkers." Doctoral thesis, Università degli Studi di Trieste, 2016. http://hdl.handle.net/11368/2908095.

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I have been successful in improving and developing a homemade device based on a three-electrodes electrochemical redout setup thanks to it, we are able to perform measurements of DNA-hybridization, in real-time, from probe ssDNA-SAMs coupled to gold coated sensor surfaces. The measurements were carried out, in pure saline buffer solution, on a large range of concentrations of complementary-DNA strands (from 1 pM to 100 nM), monitoring the differential capacitance at the Working Electrode versus the incubation time. The studies on kinetics, modeled using the Langmuir adsorption model, not only
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Kapita, Patrick Mvemba. "Development of Measurement Systems for Biosensing Applications." Doctoral thesis, Università di Siena, 2020. http://hdl.handle.net/11365/1111250.

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A health condition called “Oxidative Stress” (OS), resulting from an excessive level of Reactive Oxygen Species (ROS) is a “state harmful to the body, which arises when oxidative reactions exceed antioxidant reactions because the balance between them has been lost”[1] OS appears to be associated with and might be a cause of, many serious diseases such as cardio-vascular accidents, cancer, Parkinson’s and Alzheimer’s[2]. This is not surprising as ROS are free oxygen radicals that can attack lipids, proteins, cellular membranes, enzymes and even modify DNA. Extensive correlation studies have s
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Fuku, Xolile Godfrey. "Cytochrome C biosensor for the determination of trace level arsenic and cyanide compounds." Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_4183_1319807269.

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In this work, an electrochemical method based on a cyt c biosensor has been developed, for the detection of selected arsenic and cyanide compounds. Boron Doped Diamond (BDD) electrode was used as a transducer, onto which cyt c was immobilised and used for direct determination of Prussian blue, potassium cyanide and arsenic trioxide by inhibition mechanism. The sensitivity as calculated from cyclic voltammetry (CV) and square wave voltammetry (SWV), for each analyte in phosphate buffer (pH= 7) was found to be (1.087- 4.488 ×10-9 M) and the detection limits ranging from 0.0043- 9.1 μM. These v
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"A Multiplexing Immunosensor for the Quantification of Cytokine Biomarkers." Doctoral diss., 2012. http://hdl.handle.net/2286/R.I.15805.

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abstract: Biosensors offer excellent diagnostic methods through precise quantification of bodily fluid biomarkers and could fill an important niche in diagnostic screening. The long term goal of this research is the development of an impedance immunosensor for easy-to-use, rapid, sensitive and selective simultaneously multiplexed quantification of bodily fluid disease biomarkers. To test the hypothesis that various cytokines induce empirically determinable response frequencies when captured by printed circuit board (PCB) impedance immunosensor surface, cyclic voltammetry (CV) and electrochemic
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Conference papers on the topic "EIS-biosensor"

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Taing, Meng, and Denis Sweatman. "Fabrication techniques for an arrayed EIS biosensor." In 2009 11th Electronics Packaging Technology Conference (EPTC). IEEE, 2009. http://dx.doi.org/10.1109/eptc.2009.5416557.

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Taing, M., and D. Sweatman. "Microfabricated EIS biosensor for detection of DNA." In Microelectronics, MEMS, and Nanotechnology, edited by Dan V. Nicolau. SPIE, 2005. http://dx.doi.org/10.1117/12.638652.

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Tseng, Shin-Hua, Dion T. Tseng, Tzu-Cheng Lee, et al. "Ultra Sensitive Detection of Eneterovirus 71 by Modified Electrochemical Impedance Spectroscopy." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13143.

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The enterovirus 71 (EV71) has threatened Taiwan for more than ten years. Since traditional diagnostic methods are complicated, time consuming, and high-qualified personnel required. Therefore, a new detection process is highly desired. In this study, a high sensitive PC-based electrochemical analyzing system with a functionalized nano-gold modified immunological electrode are developed to detect EV71. Immobilizing specific EV71 polyclone antibodies, which is developed by center for disease control (CDC) Taiwan, onto nano gold of sensing electrode, the affinity interaction of the immobilized an
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Wang, Gou-Jen, Yi-Fen Liu, and Chia-Che Wu. "In-Vitro Allergy Detection Using a Silver Nanoparticle Modified Nanostructured Biosensor." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-70299.

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IgE (Immunoglobulin E) in the serum of an asthma patient is a useful index for allergy diseases. In this study, a nanostructured biosensor having uniformly deposited gold nanoparticles (GNPs) as the sensing electrode was used for fast and low serum consuming detection of the IgE in allergy patients’ serum. To enhance the charge transferring efficiency of the biosensor, silver nanoparticles (SNPs) were deposited on the GNP layer. The group 2 allergen, Der p2, was used as the probe to detect IgE. To ensure the specificity of detection, the affinity purified goat anti-Human IgE antibody was furth
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Lin, Ying-Ting, Iren Kuznetsova, and Gou-Jen Wang. "Genetically Modified Soybean Detection Using a Biosensor Electrode With Self-Assembled Gold Nanoparticles on a Micro Hemisphere Array." In ASME 2019 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/detc2019-97112.

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Abstract Gene transfer technology changes some of the characteristics of crops. However, genetically modified foods have been reported to have an impact on human health. We proposed a cost effective and highly sensitive biosensor electrode with self-assembled monolayer of gold nanoparticle on a micro hemisphere array to detect genetically modified soybean. An ordered array of micro hemispherical features was formed on a 6-inch reclaimed silicon wafer using photolithography. Then, a thin gold layer was sputtered onto the hemispheres. The wafer was then immersed into a 5 mM ethanol solution of 1
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Wang, Wei-Jhen, Chia-Hwa Lee, Chin-Wen Li, Stephen Liao, Fuh-Jyh Jan, and Gou-Jen Wang. "Direct Label Free Detection of Orchid Virus Using a Micro/Nano Hybrid Structured Biosensor." In ASME 2019 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/detc2019-97198.

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Abstract In this study, a label-free detection approach for effective detection of the odontoglossum ringspot virus (ORSV) infected orchids has been developed. We used semiconductor fabrication process to fabricate 1,810 micro/nano hybrid structured sensing electrodes on a 8 inch reclaimed wafer. The self-assembled monolayer (SAM) process was then employed to sequentially modify the electrode surface with 11-mercaptoundecanoic acid (11-MUA), 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC)/ N-hydroxysuccinimide (NHS), anti-ORSV, and ORSV. EIS was conducted for the ORSV concentration detect
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Chen, Chun-Cheng, and Gou-Jen Wang. "PCR Free Detection of Hepatitis B Virus DNA Using a Nanostructured Impedance Biosensor." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-34866.

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In this study, a PCR free technique for effective detection of hepatitis B virus (HBV) DNA obtained directly from clinical samples was presented. The honeycomb-like barrier layer of an anodic aluminum oxide (AAO) film having a uniform nanohemisphere array was used as the substrate of the sensing electrode. A gold thin film about 30 nm thick was radio-frequency (RF) magnetron sputtered onto the AAO barrier-layer surface as the electrode for the successive deposition of gold nanoparticles (GNPs) on the hemisphere surface. A specially designed single-strand 96-mer gene fragment of the target geno
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