Academic literature on the topic 'EHF-dielectrometry'

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Journal articles on the topic "EHF-dielectrometry"

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Kashpur, V. A., V. Ya Maleev, and O. V. Khorunzhaya. "APPLICATION OF DIFFERENTIAL EHF DIELECTROMETRY IN MOLECULAR BIOPHYSICS." Telecommunications and Radio Engineering 69, no. 16 (2010): 1473–89. http://dx.doi.org/10.1615/telecomradeng.v69.i16.80.

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Dreval, N. V., T. Yu Shchegoleva, V. G. Kolesnikov, A. P. Belozorov, and E. I. Milyutina. "Application of EHF-Dielectrometry Method in Studying Growth Phases of E.Coli Cells." Telecommunications and Radio Engineering 57, no. 8-9 (2002): 5. http://dx.doi.org/10.1615/telecomradeng.v57.i8-9.190.

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Shestopalova, Anna Victorovna, Daryna A. Pesina, Vsevolod A. Kashpur, and Olga V. Khorunzhaya. "Hydration of DNA-binding biological active compounds: EHF dielectrometry and molecular modeling results." Structural Chemistry 27, no. 1 (November 17, 2015): 159–73. http://dx.doi.org/10.1007/s11224-015-0695-4.

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Shchegoleva, T. Yu, and T. V. Parshikova. "Using EHF-Dielectrometry for Estimation of Viability of Some Microalgae at the Presence of Catamine." Hydrobiological Journal 42, no. 6 (2006): 72–84. http://dx.doi.org/10.1615/hydrobj.v42.i6.60.

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Maleev, V., M. Semenov, V. Kashpur, T. Bolbukh, A. Shestopalova, and D. Anishchenko. "Structure and hydration of polycytidylic acid from the data of infrared spectroscopy, EHF dielectrometry and computer modeling." Journal of Molecular Structure 605, no. 1 (February 2002): 51–61. http://dx.doi.org/10.1016/s0022-2860(01)00666-4.

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Kashpur, V., O. Khorunzhaya, and D. Pesina. "Dielectrometry of hydration of fl avin mononucleotide and DNA." RADIOFIZIKA I ELEKTRONIKA 26, no. 3 (2021): 46–53. http://dx.doi.org/10.15407/rej2021.03.046.

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Subject and Purpose. The elucidation of the molecular mechanisms of action of biomolecules is necessary for the development of state-of-the-art means of diagnosing and treatment. Dielectric studies in the millimeter wave range are effective for puzzling out the nature of the interaction of biomolecules with a surrounding aqueous solvent. Flavin mononucleotide (FMN), which can kill microorganisms and destroy cancer cells, is of particular interest. The aim of the work is to recognize hydration effects (changes in the state of water molecules) in FMN solutions. Methods and Methodology. The complex dielectric permittivity (CDP) is measured in the EHF range. Knowing the difference between the CDP of FMN solution and the CDP of water we find the difference, D es , between the effective dielectric permittivities in terms of the Debye theory of polar liquids. Since the relaxation time of dipoles of bound water is one or two orders of magnitude longer than that of free water, the amount of the difference D es characterizes the hydration of biomolecules. At low concentrations, this difference is proportional to the number of bound water molecules. Results. It has been shown that approximately18 water molecules are bound to the FMN molecule. Groups of atoms as the most probable hydration centers (primarily due to the hydrogen bonds) have been indicated. As the pH decreases, the number of water molecules bound to the Flavin mononucleotide increases to 21. The study of the FMN–DNA solution has shown that one nucleotide accounts for 25–26 bound water molecules in total. However, composing hydration numbers assumes a quantity of components less than 20. An assumption is made that the additional components are due to the cooperative nature of the hydration, leading to the fact that even if some solvent molecules do not come into a direct contact with hydration centers, they are under the influence of biomolecules all the same. Conclusion. Extremely-high-frequency dielectrometry is an effective method of research into the interaction of biomolecules with a water-ionic solvent. A FMN hydration model has been proposed, which indicates probable hydration centers and tells a measure of their effect on the solvent. It has been found that the FMN with DNA interaction increases the number of bound water molecules per one nucleotide of the DNA. The obtained results have been compared to the existing models of the DNA with FMN interaction.
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Lychko, Volodymyr S. "DIAGNOSTIC FEATURES OF DYSFUNCTION IN CYTOKINE AND SYMPATHOADRENAL SYSTEMS WITH ISCHEMIC STROKE." Wiadomości Lekarskie 73, no. 10 (2020): 2233–37. http://dx.doi.org/10.36740/wlek202010124.

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The aim: Was a comprehensive study of the changes in features like structural and functional parameters of brain tissue, cytokine profile and β-adrenoceptor in the acute period of ischemic stroke (IS) to optimise diagnosis and treatment. The study was conducted at the Department of Neurosurgery and Neurology at the Medical Institute of Sumy State University. Materials and methods: Measurements of complex dielectric constant (CDC) were performed by EHF dielectrometry. Determination of plasma levels of interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) was performed by solid-phase enzyme-linked immunosorbent assay. The work was based on the materials of a comprehensive examination of 350 patients with the first in the life of IS on the 1st, 10th and 21st day of the disease. Results: Cerebral hypoxia leads to a significant increase in the CDC of erythrocyte membranes (about 15 %), which may lead to a rise in the volume fraction of water in cell suspensions due to damage of their membrane-receptor complex (MRC). The revealed connections between changes of CDC of patients with IS and decrease insensitivity of their MRC to adrenergic drugs testify in favour of damaging action of hypoxia. An imbalance in the cytokine system and their relationship to the sympathoadrenal system has been identified. Conclusions: There is a strong association of mechanisms that damage the MRC of cells during acute cerebral ischemia with functional changes in both the sympathoadrenal and cytokine systems. Identified links in the pathogenesis of IS should be used for early diagnosis of the disease.
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"Possibilities of target neurotrophic therapy of ischemic stroke." Journal of V. N. Karazin Kharkiv National University, Series "Medicine", no. 40 (2020). http://dx.doi.org/10.26565/2313-6693-2020-40-05.

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The study aimed to comprehensively investigation the features of changes in the structural and functional characteristics of the brain tissue, cytokine profile, and β-adrenergic reception in the acute period of ischemic stroke (IS) to optimize treatment. Materials and methods. EHF dielectrometry was used to measure the complex dielectric conductivity (CDC) of peripheral blood erythrocytes in patients with IS. Changes in the osmotic resistance of erythrocytes (ORE) under the action of β-adrenergic blockers (β-AB) were determined by photoelectron colourimetry. Plasma levels of interleukin (IL)-6 and tumour necrosis factor (TNF)-α were assessed using an enzyme-linked immunosorbent assay. The basis of the work was the materials of a comprehensive examination of 350 patients with the first in life IS in the dynamics of treatment with human cryopreserved cord blood serum (CCBS). Results. In patients with IS, from the first hours of the development of the disease, there is a sharp increase in the levels of proinflammatory cytokines IL-6 and TNF-α in the blood serum (by 9.3 and 3.9 times, respectively). At the onset of IS, there is a significant increase in the level of β-ARM by 2.4 times as compared with the control and a decrease in CDC by 10.0 % after exposure to an adrenaline solution. The maximum levels of β-ARM (42.43 ± 3.64 CU) are observed in patients with initially severe disease. The established direct correlations between plasma levels of IL-6, TNF-α and β-ARM (r 0.73; p < 0.05 and r = +0,86; p < 0.05, respectively); IL-6, TNF-α and total clinical score on the NIHSS scale (r = +0.895; p < 0.05 and r = +0.9; p < 0.05, respectively). Conclusions. The study has demonstrated the positive immunomodulatory and membrane-protective effects of human CCBS in the acute period of IS. Stabilization of the absolute values of CDC indicated changes in the levels of cell hydration, causing the activation of not only the membrane receptor complex (MRC) of erythrocytes but also an increase in the functional characteristics of the sympathoadrenal system (SAS). The use of CCBS caused a more significant and rapid decrease in the concentrations of the central proinflammatory cytokines IL-6 and TNF-α, which indicated the regulatory effect of the drug in suppressing the local inflammatory response initiated by hypoxia.
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Dissertations / Theses on the topic "EHF-dielectrometry"

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Soloshenko, E. N., A. K. Kondakov, N. V. Khmil, V. G. Kolesnikov, Z. M. Shevchenko, and T. P. Yarmak. "Effect of local anesthetics on cells hydration at drug-receptor reactions." Thesis, Ivan Franko National University of Lviv, 2016. http://openarchive.nure.ua/handle/document/10387.

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By means of EHF-dielectrometry method it is shown that stimulation of red blood cells by articaine, ubistesin and septonest has been differently reflected in change of a real part of permittivity (). Findings by method EHF-dielectrometry and also erythrocyte sedimentation rate were good correlated (r  0,92) that allows to recommend this radio physical method for diagnostics of early revealing of a sensitization to medicinal allergens
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Book chapters on the topic "EHF-dielectrometry"

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Maleev, Vladimir Ya, Mikhael A. Semenov, Vsevolod A. Kashpur, Tom V. Bolbukh, and Anna V. Shestopalova. "Hydration and conformations of polycytidylic acid from the data of infrared spectroscopy, EHF dielectrometry and Monte Carlo simulation." In Spectroscopy of Biological Molecules: New Directions, 227–28. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4479-7_97.

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Conference papers on the topic "EHF-dielectrometry"

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Soloshenko, E., A. Kondakova, V. Kolesnikov, N. Khmel, Z. Shevchenko, T. Yarmak, and V. Korzh. "Operation monitoring of allergic reaction to artifrin by means of EHF-dielectrometry method." In 2013 International Kharkov Symposium on Physics and Engineering of Microwaves, Millimeter and Submillimeter Waves (MSMW). IEEE, 2013. http://dx.doi.org/10.1109/msmw.2013.6622122.

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