Dissertations / Theses on the topic 'Efficacy of medications'

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1

Melius, Joyce. "Mathematics Anxiety and Mathematics Self-efficacy in Relation to Medication Calculation Performance in Nurses." Thesis, University of North Texas, 2012. https://digital.library.unt.edu/ark:/67531/metadc115119/.

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The purpose of this study is to identify and analyze the relationships that exist between mathematics anxiety and nurse self-efficacy for mathematics, and the medication calculation performance of acute care nurses. This research used a quantitative correlational research design and involved a sample of 84 acute care nurses, LVNs and RNs, from a suburban private hospital. the participants filled out a Mathematics Anxiety Scale, a Nurse Self-Efficacy for Mathematics Scale and also completed a 20-item medication calculation test. Significant practical and statistical relationships were discovered between the variables utilizing multiple linear regression statistics and commonality analysis. As the Nurse’s Mathematics anxiety score increased the scores on the medication test decreased and the scores on nurse self-efficacy for mathematics scale also decreased. the demographic item of “Hours a nurse worked in one week” had the greatest significance. the more hours a nurse worked the lower their score was on the medication calculation test. This study agrees with others that nurses are not good at mathematics. This study also correlated that as the number of hours worked increased so did the medication calculations errors. and many nurses have a measurable level of anxiety about mathematics and dosage calculations and this may influence calculation ability. Suggestions for further research include refinement of instruments used in study, further differentiation of barriers to successful medication calculation performance, and testing of interventions used to teach, train and evaluate accurate medication administration in nurses.
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Sarwary, Mariam. "Comparison of cognitive decline medications of Alzheimer´s disease : Efficacy and safety of Donepezil, Galantamine, Rivastigmine and Memantine." Thesis, Umeå universitet, Farmakologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-136250.

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3

Velazquez, Raquel. "The efficacy of anti-psychotic medications in treating the behavior, social, and communication deficits associated with autism spectrum disorders in children and adolescents a systematic review." Honors in the Major Thesis, University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/636.

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Background: Autism spectrum disorders (ASD) are a group of complex developmental disabilities which can cause behavior, social, and communication deficits. Anti-psychotic medications are often prescribed when symptoms such as aggression, irritability, hyperactivity, tantrums, and self-injurious behavior occur. Objective: To determine if anti-psychotic medications improve the behavior, social, and communication symptoms associated with ASD in children and adolescents. Search Strategy: Electronic literature searches were performed to find relevant studies and utilized the (1) Cochrane Database of Systematic Reviews, (2) Hispanic American Periodicals Index, (3) Medline, (4) PAIS International, (5) ProQuest Dissertations and Theses, (6) PsycInfo, (7) PubMed, (8) Springer LINK, (9) Taylor and Francis Journals, and (10) Sage Premier. Selection Criteria: Randomized controlled trials (RCTs) or quasi-experimental design (QED) studies of any dose of an anti-psychotic medication compared to a placebo or other prescription drug, in participants with autism spectrum disorder. Data Collection and Analysis: All studies which met the full-text level criteria were reviewed by a third party to validate the decision of inclusion. Meta-analyses in this review implemented both random and fixed-effects models. Main Results: Ten RCTs were included. Six studies evaluated a drug versus a placebo and four studies investigated the effects of two separate anti-psychotic medications or the efficacy of an additive medication to a drug and placebo group. Author's Conclusions: Limited evidence suggests the effectiveness of anti-psychotic medications in treating the behavior, social, and associated with autism; however, further research is needed to determine the implications of long-term use.
B.A. and B.S.
Bachelors
Office of Undergraduate Studies
Interdisciplinary Studies
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Cerminara, Zak, Jill Augustine, Tracy Harrell, and Kevin Boesen. "A Comparison of the Efficacy of Two Types of Faxed Medication Interventions." The University of Arizona, 2014. http://hdl.handle.net/10150/614149.

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Class of 2014 Abstract
Specific Aims: To assess the impact of provider outreach for an MTM program by comparing two formats of recommendations: a general informational fax and a prescription template fax. Methods: This study was a retrospective analysis of pharmacist recommendations at an MTM center in 2012. Recommendations were made following either a comprehensive medication review with a patient or of available pharmacy claims. Interventions included in this analysis were those made to improve patient treatment through the use of medications consistent with national treatment guidelines (“guideline alerts”) or those made to reduce cost (“cost alerts”). A recommendation was a success if the change in medication therapy was noted in claims data within 120 days. The success rates between the two interventions were compared using Chi square. Main Results: The overall success rate was 20.9% (10,947/52,409). For guideline alerts, there was a significant difference in the acceptance of prescription faxes (13.1%) versus informational faxes (9.9%) (P <0.001). Prescription faxes recommending the addition of an ACE inhibitor for hypertension in diabetic patients was significantly higher compared to informational faxes in females over 60 years old (14.8% vs. 10.00%, P <0.001) and all males (13.2% vs. 9.9%, P <0.001). For cost alerts, there was a statistically significant difference in the acceptance of prescription faxes (49.7%) versus informational faxes (37.7%) (P <0.001). Conclusion: Prescription faxes produce higher rates of acceptance for guideline and cost recommendations. While both prescription and informational faxes could be used to further improve the communication between prescribers and pharmacists that provide MTM services, providers may prefer specific prescription faxes.
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Seng, Elizabeth K. "Development of the Acute Medication Self-Efficacy Scale for Headache." Ohio University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1344946467.

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6

Becker, Kathleen Ann. "Efficacy of a behavioral intervention to decrease medication transcription errors among professional nurses." [Milwaukee, Wis.] : e-Publications@Marquette, 2009. http://epublications.marquette.edu/dissertations_mu/2.

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7

Paterson, Ruth Elizabeth. "Development and evaluation of a theoretical model to predict medicines adherence in people with mild to moderate intellectual disability and diabetes : a mixed methods study." Thesis, Edinburgh Napier University, 2018. http://researchrepository.napier.ac.uk/Output/1526669.

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Background: Fifty percent of medications are not taken as prescribed. This is a major public health issue yet there is very limited evidence on the factors associated with medicines adherence in people with mild to moderate Intellectually Disabilities and diabetes (IDD). This study evaluated the frequency of, and factors associated with, medicines non-adherence in this group compared to people without ID but with diabetes (non-IDD).Methods: A systematic review of the literature informed the theoretical model tested. A two-stage, sequential mixed methods study with 111 people with type 1 and 2 diabetes, (IDD = 33, non-IDD = 78) was then carried out. Stage one (quantitative) compared frequency of medication adherence in the group overall, IDD and non-IDD. Univariate and multiple regression analysis evaluated associations between factors (ID, depression, side effects, self-efficacy and perceived level of social support) and medicines non-adherence. Stage two (qualitative) explored findings of stage one with 12 stage one participants' carers using semi-structured interviews. Results: Data were collected between July 2014 and May 2016. The frequency of medicines adherence was similar in the IDD and non-IDD population (70% vs 62%, p = 0.41). The theoretical model did not predict medicines non-adherence. After controlling for support with medicines and complexity of regime (number of medications and use of insulin), depression was an independent predictor in the non-IDD and group overall (p < 0.001). In the IDD group, perceived side effects was an important, but non-significant, predictor of non-adherence (p = 0.06). Carers' perceptions of adherence and depression were consistent with stage one findings. Conclusions: Optimising adherence to diabetes medicines is equally challenging in IDD and non-IDD populations. Associations between independent factors and adherence differed between the two groups: in the non-IDD population, depressive symptoms were associated with non-adherence whereas in the IDD population perceived level of side effects appeared most dominant. Due to small sample sizes findings were inconclusive therefore, a sufficiently powered study further investigating the relationship between adherence and side effects in people with ID and diabetes is recommended.
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Coleman, Kerrie. "Pediatric Medication Administration Efficacy| A High-fidelity Pediatric Simulation Workshop for Pediatric Nurses." Thesis, Carlow University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10262152.

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The purpose of this scholarly project was to examine the use of a high-fidelity simulation workshop to improve accuracy with pediatric dosage calculations among practicing pediatric nurses. The NLN Jeffries Simulation Theory provided a framework for this descriptive quantitative project. A convenience sample of 15 pediatric nurses completed a 10-question pediatric dosage calculation pre-test, a high-fidelity simulation workshop, a 10-question pediatric dosage calculation post-test, and a post-simulation evaluation survey. In addition, a one-month follow-up 10-question pediatric dosage calculation post-test and a one-month follow-up post- high-fidelity simulation workshop survey were administered via Survey Monkey©, in which 12 pediatric nurse participants completed. Pre-tests and post-tests were analyzed for central tendency and a t-test analysis was performed for statistical significance. Results revealed statistical significance between pre-test and post-test as well as statistical significance between post-test and one-month follow-up post-test. The Likert scale post-simulation survey and one month post-simulation survey were analyzed for central tendency. The results from the post simulation survey and one-month follow-up survey revealed the participants agreed to strongly agreed the high-fidelity simulation workshop impacted their proficiency and accuracy in calculating pediatric dosages. The findings from this project provides insights into the use of high-fidelity simulation as a continuing education tool for the practicing pediatric nurse in relation to pediatric medication efficacy.

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Musten, Lynette Monteiro. "Efficacy of stimulant medication treatment of attention deficit hyperactivity disorder in preschool-aged children." Thesis, University of Ottawa (Canada), 1996. http://hdl.handle.net/10393/9981.

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Longitudinal information indicates children who present with 'hard-to-manage' or problematic behaviours at a very young age are at risk for on-going difficulties with parents, peers and in school. However, there are few interventions that have demonstrated effectiveness in ameliorating the symptoms that appear to be precursors of Attention Deficit Hyperactivity Disorder (ADHD). Despite the use of methylphenidate (MPH) to treat Attention Deficit Hyperactivity Disorder in very young children, there is little information related to its efficacy within this age group. This study examined the effectiveness of medication on the cognitive, behavioural and interpersonal domains of young children who were diagnosed with ADHD. The children were assessed using cognitive measures, behavioural ratings scales and interactive measures assessing child compliance and attention. Furthermore, the effect of the children's medication status on parental style, skills and stress also were assessed using behavioural observations of parent and child engaged in interactive tasks. Changes in parental style, skills and stress were evaluated. Twenty-four children, aged 4 to 6 years, diagnosed with ADHD, participated in a double-blind, placebo-controlled study evaluating the efficacy of 0.3 mg/kg and 0.5 mg/kg methylphenidate BID. All treatments were randomized and administered for a minimum of 7 days. Results indicated improvements related to medication were obtained on measures of cognitive tests of attention and as assessed by parent rating scales. Cognitive tests of impulsivity presented an equivocal picture of sensitivity to medication treatment. Attentional abilities in an interactive setting indicated a medication response from Baseline measures only and the degree to which this effect was augmented by Placebo treatment was unclear. That is, there was some evidence that parental expectancies played a role in these measures. No changes were obtained with respect to the children's tendency to comply with parental requests. Side effects were not significantly increased with medication treatment. Parental skills appeared unaffected by the child's medication status. However, parental style appeared to become more positive especially following treatment with the higher dose. Although the stress reported to be experienced by the parent decreased following treatment, the response was non-specific, that is, not related to the medication status of the child. Not surprisingly, clinical change analyses showed parent ratings were more effective than the cognitive task in picking up the number of children who had responded favourably to medication. Parents rated many children as having improved or normalized following treatment with both doses. Similar rates of positive change were obtained with respect to negative behaviours. This investigation into the efficacy of MPH in the treatment of very young children diagnosed with ADHD indicated that it was effective in allievating symptoms of inattention as assessed by laboratory tests and by parent rating scales. Although parents rated negative behaviours as having decreased as a function of medication, these behavioural changes were not detected during the interactive tasks In general, parent-child tasks did not demonstrate the effectiveness of medication in changing the parents' behaviours or the parent-child dynamic.
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Musten, Lynette Marian Monteiro. "Efficacy of stimulant medication treatment of attention deficit hyperactivity disorder in preschool-aged children." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1996. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq26135.pdf.

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11

Rose, Olaf [Verfasser]. "Feasibility and Efficacy of a Collaborative Medication Management for Elderly, Multimorbid Patients / Olaf Rose." Bonn : Universitäts- und Landesbibliothek Bonn, 2017. http://d-nb.info/1140525859/34.

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12

David, Prema. "The Effectiveness of Educational Methods on Medication Adherence." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/212.

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Nonadherence to medications for chronic illnesses is a public health problem that requires education related to its illnesses and medications in order to reduce morbidity, mortality, and health care costs, and to improve quality of life. Scholars have identified that morbidity and mortality are much higher among African Americans due to poor medication adherence when compared to Euro-Americans. This study focused on African Americans to increase their medication adherence with chronic illnesses. The purpose of this study was to analyze the effectiveness of using different educational methods to enhance medication adherence. The social cognitive theory and the theory of planned behavior were used as a foundation to develop this quantitative study. Three validated tools were used to assess the effectiveness of educational methods to see if there would be any increase in knowledge, self-efficacy, and change in health beliefs. A sample size of 144 African Americans in Chicago with chronic illnesses was randomized to an experimental group that received education on medication adherence for a period of 8 weeks through lecture, video presentation, roleplaying, and group discussion. A control group received regular education for the same 8 weeks. ANOVA, ANCOVA, and MANOVA statistical methods were used to analyze the findings that reported no statistical significance in the knowledge difference scores F(1,261) = 0.17, p = 0.678, self-efficacy difference scores F(1,259) = 0.96, p = 0.328, and health beliefs difference scores F(4,258) = 0.46, p = 0.765. This study contributes to social change by identifying a public health problem which can be improved by adding and testing other variables such as fatigue and cognitive and sensory deficits associated with chronic illnesses, which could yield a more valuable in-depth understanding.
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Stallworthy, Pippa. "An investigation of the relationship between perceived self-efficacy and adherence to medication in HIV." Thesis, Open University, 1999. http://oro.open.ac.uk/57994/.

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New drug treatments have revolutionised the care of people with HIV, but they require exceptionally high levels of adherence. Research into the risk factors has been predominantly empirically rather than theoretically driven. Studies of adherence in other conditions have established the importance of perceived self-efficacy. Research studies exploring this relationship in HIV were conducted when the only available treatment was monotherapy, or with an exclusively female sample. This study attempted to investigate the role of self-efficacy to adherence to antiretroviral medications in a UK sample of HIV positive people. It also aimed to explore the relationship between self-efficacy and depression. Finally, the relationship between self-efficacy and coping strategies was also considered. The study employed a cross-sectional design, with all participants completing a questionnaire at one time point. Multiple regression analysis of the predictors of dose delays established that the two medication-specific self-efficacy measures accounted for 42.9% of the variance. No other predictors emerged from a stepwise regression. Use of recreational drugs was the only predictor of dose omissions to emerge from a multiple regression. However, when drug use was controlled for, self-efficacy for adherence added a further 12.7% of the variance. The findings of this study suggest that self-efficacy is related to adherence although the direction of causality remains to be established. Clearly, further research is needed to clarify the role of self-efficacy. Should it prove to be as significant as the results of this study imply, it is quickly and easily assessed and, moreover amenable to intervention.
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McEntyre, Wanda L. J. "Self-efficacy expectations, outcome expectations and the prediction of medication usage, pain level and work readiness /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487260531958244.

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Santos, Pedrosa Rafaela Batista dos 1988. "Adapatação cultural e avaliação das propriedades de medida da "Self_Efficacy for Appropriate Medication Adherence Scale - SEAMS"." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/283880.

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Orientador: Roberta Cunha Matheus Rodrigues
Texto em português e inglês
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Enfermagem
Made available in DSpace on 2018-08-25T10:11:00Z (GMT). No. of bitstreams: 1 SantosPedrosa_RafaelaBatistados_M.pdf: 1805803 bytes, checksum: 1c035d3233cb182bbb25a113e1cc2f2f (MD5) Previous issue date: 2014
Resumo: Este estudo tem como objetivo disponibilizar uma versão da Self-efficacy for Appropriate Medication Adherence Scale ¿ SEAMS para a cultura brasileira e avaliar suas propriedades de medida quando aplicada em pacientes com doença arterial coronária (DAC) em seguimento ambulatorial.. O processo de adaptação cultural foi realizado de acordo com as etapas propostas na literatura - tradução, síntese, retrotradução, avaliação por comitê de especialistas e pré-teste, seguidos pela avaliação da praticabilidade, aceitabilidade, confiabilidade e validade. Fizeram parte deste estudo 147 pacientes com DAC em uso de medicamentos cardioprotetores e de alívio dos sintomas, em seguimento ambulatorial em hospital universitário do interior do estado de São Paulo. Os dados foram obtidos por meio de entrevista e aplicação de instrumento de caracterização sociodemográfica/clínica e das versões brasileiras da Morisky Self-Reported Measure of Medication Adherence Scale (MMAS-4), da General Perceived Self-Efficacy Scale (GSE) e da SEAMS. A praticabilidade foi avaliada pelo tempo despendido na entrevista e a aceitabilidade pela proporção de pacientes que responderam a todos os itens do instrumento. Foi estimada a confiabilidade no que se refere à consistência interna e estabilidade da medida. A validade de construto foi estimada pela evidência correlacional entre os escores da versão brasileira da SEAMS, da MMAS-4 e da GSE. A validade de grupos conhecidos foi testada entre aqueles classificados com "dose suficiente" e "dose insuficiente" ( medida da proporção de adesão) e entre aqueles "aderentes" e "não aderentes" (medida da avaliação global da adesão). Foi empregada a análise confirmatória de fatores por meio dos modelos de equações estruturais A validade convergente do modelo fatorial foi avaliada pelas medidas de Average Variance Extracted (AVE), magnitude das cargas fatorias, alfa de Cronbach e confiabilidade composta. A validade discriminante do modelo fatorial foi avaliada pelas análises das cargas fatoriais cruzadas, comparação entre as raízes quadradas das AVEs, pelos coeficientes de correlação entre os construtos e pela correlação desatenuada. Os dados foram submetidos às análises descritivas, com avaliação da praticabilidade, aceitabilidade e efeitos teto e chão; de confiabilidade por meio do coeficiente alfa de Cronbach (consistência interna) e do coeficiente de correlação intraclasse (estabilidade da medida). O coeficiente de correlação de Spearman foi utilizado para testar a correlação entre os escores das versões brasileiras da SEAMS, MMAS-4e GSE. O teste de Mann-Whitney foi utilizado para verificar a capacidade da versão brasileira da SEAMS em discriminar entre coronariopatas classificados em "dose suficiente" ou "insuficiente" e entre aqueles "aderentes" e "não aderentes" ao tratamento medicamentoso. A versão traduzida da SEAMS apresentou evidências de equivalências semântico-idiomática, conceitual e cultural, com elevada aceitabilidade e praticabilidade. Foi evidenciado efeito chão para o escore total e domínios da SEAMS. Os achados evidenciaram confiabilidade da medida - coeficiente de correlação intraclasse (0,99) e coeficiente alfa de Cronbach (entre 0,85-0,90). Foram constatadas correlações significativas negativas de moderada a forte magnitude com os escores da MMAS-4, porém não foram encontradas correlações com os ecores da medida geral de autoeficácia. A validade de grupos conhecidos foi apoiada, uma vez que a escala discriminou entre aderentes e não aderentes ao tratamento medicamentoso. A análise fatorial confirmatória confirmou a estrutura de fatores do instrumento original. Os resultados evidenciaram cargas fatoriais cruzadas ? 0,50 para todos os itens da escala nos domínios em que foram alocados no instrumento original, AVE=0,52 para o fator 1 e 0,69 para o fator 2 e confiabilidade composta de 088 e 0,99 para os fatores 1 e 2, respectivamente, apontando para a validade convergente do modelo. Foram constatadas valores superiores de cargas fatoriais cruzadas para todos os itens da escala nos domínios em que foram previamente designados no instrumento original, raízes quadradas de AVEs superiores às correlações entre os construtos e correlação desatenuada (r=0,83), sugerindo validade discriminante do modelo. A confiabilidade de ambos os fatores, estimada de acordo com a homogeneidade dos itens, apontou para confiabilidade e validade de construto convergente da versão brasileira da SEAMS. Os achados apontam para confiabilidade e validade de construto da versão brasileira da SEAMS entre coronariopatas em seguimento ambulatorial
Abstract: This study aims to provide a version of the Self-efficacy for Appropriate Medication Adherence Scale - SEAMS for Brazilian culture and evaluate its measurement properties when applied to patients with coronary artery disease (CAD). The process of cultural adaptation was performed according to the steps proposed in the literature - translation, synthesis, back translation, expert committee review and pretesting, followed by evaluation of the feasibility, acceptability, reliability and validity. This study included 147 patients with CAD in the use of cardioprotective medications and relief of symptoms in outpatients at a university hospital in the state of São Paulo. Data were obtained by interview and instrument sociodemographic / clinical characterization and Brazilian versions of Morisky Self-Reported Measure of Medication Adherence Scale (MMAS-4), the General Perceived Self-Efficacy Scale (GSE) and SEAMS. Practicality was assessed by time spent in the interview and the acceptability by the proportion of patients who responded to all items of the instrument. Reliability with respect to the internal consistency and stability of the measurement was estimated. Construct validity was estimated by correlational evidence between the scores of the Brazilian version of SEAMS, the MMAS-4 and GSE. Known groups validity was tested between those classified as "sufficient dose" and "insufficient dose" (measure of the proportion of membership) and among those "adherent" and "nonadherent" (measure of overall assessment of compliance). Was used confirmatory factor analysis through structural equation models Convergent validity of the factorial model was evaluated by measurements of Average Variance Extracted (AVE), magnitude of loads fatorias, Cronbach's alpha and composite reliability. The discriminant validity of the model was evaluated by factorial analysis of cross-factor loadings, comparing the square roots of AVEs, the correlation coefficients between the constructs and the correlation desatenuada. Data were subjected to descriptive analyzes, assessing the feasibility, acceptability and ceiling and floor effects; reliability through Cronbach alpha (internal consistency) and the intraclass correlation coefficient (measurement stability). The Spearman correlation coefficient was used to test the correlation between the scores of the Brazilian versions of SEAMS, MMAS-4e GSE. The Mann-Whitney test was used to verify the ability of the Brazilian version of the SEAMS in discriminating between coronary classified as "adequate dose" or "insufficient" and among those "adherent" and "nonadherent" to drug treatment. The translated version of SEAMS presented evidence of idiomatic semantic-conceptual and cultural equivalence, with high acceptability and feasibility. Floor effect was evidenced for the total score and domains of SEAMS. The findings indicate reliability of the measure - the intraclass correlation coefficient (0.99) and Cronbach's alpha coefficient (between 0.85-0.90). Significant negative correlations of moderate to strong magnitude with the scores of MMAS-4 were observed, but no correlations with ecores general measure of self-efficacy were found. Known groups validity was supported, since the scale discriminated between adherent and non-adherent to medication treatment. Confirmatory factor analysis confirmed the factor structure of the original instrument. Results showed cross-factor loadings ? 0.50 for all items of the scale in areas that were allocated in the original instrument, AVE = 0.52 for factor 1 and 0.69 for factor 2 and composite reliability of 0.88 and 0.99 for factors 1 and 2, respectively, indicating the convergent validity of the model. Higher values of cross-factor loadings for all scale items in domains that were previously designated in the original instrument, the square roots of higher than the correlations between constructs and desatenuada correlation (r = 0.83) strokes were observed, suggesting discriminant validity of model. The reliability of both factors, estimated according to the homogeneity of the items pointed to reliability and convergent validity of the Brazilian version of the SEAMS. The findings point to reliability and construct validity of the Brazilian version of SEAMS between coronary outpatients
Mestrado
Enfermagem e Trabalho
Mestra em Ciências da Saúde
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Trairatvorakul, Pon. "Cardiovascular Safety of Stimulant Medication in Children with Congenital Heart Disease and Attention Deficit/Hyperactivity Disorder." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1459529300.

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Cheesman, C. "The presented case study aims to demonstrate the efficacy of psychotherapy with a child previously treated with medication." Thesis, Rhodes University, 1988. http://hdl.handle.net/10962/d1007730.

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The impetus for using the therapy with J.B. for this study was primarily the challenge inherent in the situation from the moment the parents and J.B. arrived for their family interview and assessment. They had been through many professionals by then, and much medication. They were sceptical of our intervention, since nothing to date had relieved the situation, and J.B. still had outbursts of rage towards his mother, he was still expressing suicidal ideation and anxiety. The challenge was particularly in relation to the mother, who had great difficulty conceptualising J.B. 's problems as being emotional and relational in nature - she was infinitely more comfortable with physiological interpretations of everything. This had the effect on the therapist and the supervisor of frequently reassuring their belief in psychotherapy as the treatment of choice in this case, or if in fact there was a lurking 'disease ' or organic cause to the child's behaviour. The pressure was thus considerable in this respect, despite the fact that the child had been examined physically and nothing found. This study aims to demonstrate the efficacy of psychotherapy, and the changes that took place, with this patient who was previously treated with medication.
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Allison, Ok Chon. "The Relationship of Metabolic Control to Hardiness, Self-Efficacy, and Perceived Medication Adherence in Adults with Diabetes Mellitus." VCU Scholars Compass, 2003. http://scholarscompass.vcu.edu/etd/3994.

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Diabetes mellitus, a serious and costly disease, is a public health challenge. Diabetes is controllable, yet non-adherence to prescribed medications causes diabetesrelated complications resulting in hospital admissions and readmissions that may be prevented. A cross-sectional, descriptive-correlational study was conducted to investigate the relationship of metabolic control (A1C) to hardiness, self-efficacy, and perceived medication adherence. Health-Related Hardiness Scale (Pollock, 1990); Long-Term Medication Behavior Self-Efficacy Scale (De Geest et al., 1994); and Perceived Medication Adherence Scale (Allison, 2000) were administered to 215 participants. Data analyses of correlation and multiple linear regression using SPSS 10.0 statistical software were performed. Metabolic control was not significantly predicted by hardiness, self-efficacy, and perceived medication adherence. However, 42% (n = 88) had A1C level < 7%. The Perceived Medication Adherence Scale was found to be of one factor structure and reliable. The findings indicate that physiological phenomena were not predicted by self-reported behavioral phenomena. Further research using an intervention study, such as patient education and/or telephone followup intervention in conjunction with diet and medication therapy needs to be conducted to determine whether metabolic control will be improved in adults with diabetes mellitus.
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Aghighi, Sonja Anahita [Verfasser]. "Analgesic efficacy of gabapentin as add-on medication in the postoperative period after hemilaminectomy in dogs / Sonja Anahita Aghighi." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2010. http://d-nb.info/1009660837/34.

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Hand, Denise Catherine. "Cardiovascular, endocrine and affective responses to an acute psychosocial stressor, the impact of objective control, self-efficacy and oral contraceptive medication." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ62345.pdf.

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Chinthammit, Chanadda. "A Single-Blind, Randomized, Controlled study of Efficacy and Effectiveness of Pharmacy Quality Improvement." Thesis, The University of Arizona, 2014. http://hdl.handle.net/10150/323441.

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Background: The Alliance for Patient Medication Safety (APMS) helps community pharmacies comply with continuous quality improvement requirements of many states and third party payment contracts through use of their Pharmacy Quality Commitment (PQC) program. Aims: To assess changes in the incidence of prescription Quality Related Events (QREs) and adoption of patient safety culture attitudes after guided PQC implementation. Methods: Twenty-one pharmacies were randomized to standard PQC practices (control) or guided PQC implementation (treatment). Pharmacy staff completed retrospective pre and post safety culture questionnaires. Negative binomial mixed and linear regression analyses were employed to examine changes in QREs rates and attitudes, respectively. Rasch analysis was used to assess questionnaire validity and reliability. Results: During the 2-month study period 3,343 QREs were reported to the online PQC system. At baseline, no difference in the average QRE reporting rate was identified between groups. Treatment group QRE reporting rates differed in one category post treatment (more incorrect safety caps QREs reported in treatment group, p<0.034). Seventy-one employees completed the questionnaire (70% response). Attitude improvement in the treatment group was 36% greater than in control (p<0.0001). The questionnaire demonstrated acceptable reliability and validity evidence. Conclusions: Guided PQC implementation increased reporting of certain QREs and increased the adoption of patient safety culture attitudes among staff pharmacy.
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Nugent, Nicole Renee. "THE EFFICACY OF EARLY PROPRANOLOL ADMINISTRATION AT PREVENTING/REDUCING PTSD SYMPTOMS IN CHILD TRAUMA VICTIMS: PILOT." [Kent, Ohio] : Kent State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=kent1182616758.

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Ehrle, Anna [Verfasser]. "Evidence-based review of efficacy and adverse effects of joint medication and evaluation of synovial fluid and serum markers for osteoarthritis in the horse / Anna Ehrle." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1096221144/34.

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Victory, Gerard. "Wellbeing and medication adherence in populations living with HIV : the efficacy of motivational interviewing and exploration of the role of stigma, self compassion and psychological flexibilty." Thesis, Queen's University Belfast, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713458.

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Bonnet, Margaretha Elizabeth. "Core self-evaluations as a moderator for the effects of role overload and powerlessness on ill-health / Margaretha Elizabeth Bonnet." Thesis, North-West University, 2007. http://hdl.handle.net/10394/704.

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Employees in the Occupational Risk Division (ORD) of a large petrochemical company experience many difficult situations on a regular basis. This division of the company comprises the emergency services, the security and the occupational health divisions of the company. Even though every precaution is taken to ensure the safety of employees in the company, accidents and incidents do happen. The employees of the ORD are confronted with gruesome accidents, dangerous accident scenes where they have to enter when everyone else is evacuated, and security breeches where they may have to enter and resolve serious conflict situations. The possibility that their work climate may contributed to their mental health status is suggested. It is suspected that the stress of the job affects the mental health of the employees of the OCD, and ways need to be found to reduce these effects. The objective of this research was to determine the relationship between core self-evaluations, role overload, powerlessness and health indicators of employees in the ORD of a large petro-chemical company and to determine whether core self-evaluations act as a moderator in the relationship between role overload and powerlessness on the one hand and health indicators on the other hand. A cross-sectional design was used. The sample consisted of 299 employees from the Occupational Risk Division of the organization. Age, gender and level of education were included as control variables. A comprehensive survey containing the measuring instruments was administrated. Descriptive statistics and inferential statistics were used to analyse the data. Results obtained indicated that some of the scales were not reliable. Powerlessness was dropped from the analysis and qualitative and quantitative role overload were collapsed into a total overload measure. The results showed that a negative relationship exists between role overload and core self-evaluations. A positive relationship exists between role overload and neuroticism, poor health and depression. Self-esteem, self-efficacy and locus of control are negatively related to neuroticism and health, and neuroticism is positively related to poor health. Depression was predicted by experiences of overload, levels of self-efficacy, locus of control and negative affect (Neuroticism). General health was predicted by experiences of overload, locus of control, neuroticism and the interaction between overload and self-esteem. None of the scales predict medication use to a significant degree. Results further indicated that only self-esteem acts as a moderator in the relationship between role overload and general health, but none of the variables of core self-evaluations act as a moderator between role overload and depression or between role overload and the use of medication. By way of conclusion, recommendations for future research were made.
Thesis (M.A. (Industrial Psychology))--North-West University, Potchefstroom Campus, 2008.
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Corbi, Inaiara Scalçone Almeida. "Efeitos de um programa educativo na qualidade de vida relacionada à saúde e na adesão à terapia de anticoagulação oral: estudo clínico randomizado." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/22/22132/tde-22052014-163837/.

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Estudo experimental com designação aleatória em dois grupos (Intervenção ou Controle) que avaliou a qualidade de vida relacionada à saúde e a adesão ao tratamento medicamentoso de pacientes que internaram para o ajuste da dosagem do anticoagulante oral, segundo a participação em um programa educativo (Grupo Intervenção - GI) ou cuidado de rotina (Grupo Controle - GC). Os grupos também foram comparados segundo a autoeficácia geral e presença de sintomas de ansiedade e de depressão em dois momentos: na internação (T1) e dois meses após a alta hospitalar (T2). O estudo foi desenvolvido em um hospital público do interior do Estado de São Paulo, de março de 2011 a dezembro de 2012. Foram considerados elegíveis para o estudo 113 pacientes, aleatorizados em GC (n=58) e GI (n=55). A aleatorização foi realizada após a estratificação pelo The Outpatient Bleeding Risk Index conforme o risco de sangramento (baixo, médio e alto risco). Os pacientes que participaram do programa educativo receberam orientações individualizadas, com uso de materiais ilustrativos na internação. Após a alta as orientações eram feitas por contatos telefônicos realizados na primeira e quarta semanas. Para a avaliação das variáveis de interesse foram utilizadas as versões validadas para o português do Brasil dos instrumentos Duke Anticoagulation Satisfaction Scale, Medidas de Adesão ao Tratamento, Hospital Anxiety and Depression Scale e General Perceived Self-Efficacy Scale. Ao final dos dois meses de seguimento, completaram o seguimento 44 participantes no GC (75,8% dos participantes em T1) e 38 no GI (69,1%). Os dados foram avaliados por estatística descritiva e de comparação das médias das variáveis de interesse entre os grupos (t de Student independente) e intragrupos (teste t de Student pareado), na internação e dois meses após a alta. O nível de significância adotado foi de 0,05. Na comparação dos grupos de pacientes que completaram ou não o seguimento, verificamos semelhanças sociodemográficas, clínicas e relacionadas à terapia de anticoagulação oral. Essas semelhanças também foram observadas ao compararmos os grupos, controle e intervenção, durante a internação. Com relação à qualidade de vida relacionada à saúde, adesão ao tratamento, sintomas de ansiedade e depressão e autoeficácia, os resultados obtidos constatam semelhanças entre GC e GI tanto em T1 quanto em T2, não confirmando as hipóteses do nosso estudo para T2. Em T2, não foi possível confirmar as diferenças entre as medidas de QVRS (p=0,65), adesão (p =0,89), ansiedade (p=0,20), depressão (p=0,27) e autoeficácia (p=0,65), considerando a participação no programa educativo. Diante dos resultados obtidos no presente estudo concluímos que para os pacientes que já possuem a experiência anterior do uso do anticoagulante oral a estratégia educativa utilizada não foi eficiente para melhorar as variáveis respostas escolhidas. Esse resultado, do ponto de vista clínico, tem uma relevante importância para os profissionais da saúde que assistem esta população de usuários de anticoagulantes orais. Nossa afirmação se pauta no conhecimento produzido por estudo anterior realizado pelo nosso grupo de pesquisa, o qual obteve resultados estatisticamente significantes e melhores para o grupo intervenção. Ao compararmos as populações dos dois estudos, ambos realizados na mesma instituição hospitalar, temos/percebemos que há diferença entre elas apenas na variável tempo de uso do medicamento. Assim, o profissional deve considerar que o tempo que o paciente faz uso do medicamento é um fator decisivo na escolha da estratégia educativa que deverá utilizar
Experimental study with random distribution in two groups (Intervention or Control), which assessed the health-related quality of life and medication treatment adherence of patients who were hospitalized to adjust the oral anticoagulation drug dosage, according to their participation in an educational group (Intervention Group - IG) or in routine care (Control Group - CG). The groups were also compared according to their general self-efficacy and presence of anxiety and depression symptoms at two times: upon hospitalization (T1) and two months after discharge from hospital (T2). The study was developed at a public hospital in the interior of São Paulo State, Brazil, from March 2011 till December 2012. In total, 113 patients were considered eligible for the study, randomized between CG (N=58) and IG (N=55). The randomization took place after the patients\' stratification into low, medium and high bleeding risk, according to The Outpatient Bleeding Risk Index. The patients who participated in the educative program received individualized orientations, using illustrative material, during the hospitalization. After discharge, the orientations were provided through telephone contact during the first and fourth week. To assess the research variables, the versions of the Duke Anticoagulation Satisfaction Scale, Treatment Adherence Measures, Hospital Anxiety and Depression Scale and General Perceived Self-Efficacy Scale validated for Brazilian Portuguese were used. After two months of monitoring, 44 participants completed the follow- up in CG (75.8% of participants at T1) and 38 in IG (69.1%). The data were assessed by means of descriptive statistics and comparison of means for the variables of interest between the groups (independent Student\'s t) and intra-groups (paired Student\'s t-test), upon the hospitalization and two months after discharge. The significance level adopted was 0.05. When comparing the patient groups that completed the follow-up or not, we found similarities in sociodemographic and clinical variables and related to the oral anticoagulation therapy. These similarities were also observed when comparing the control and intervention groups during the hospitalization. As regards the health-related quality of life, treatment adherence, anxiety and depression symptoms and self-efficacy, the results reveal similarities between CG and IG at T1 and T2, not confirming our study hypotheses for T2. At T2, the differences in the HRQoL (p=0.65), adherence (p=0.89), anxiety (p=0.20), depression (p=0.27) and self- efficacy (p=0.65) scores could not be confirmed when considering the participation in the educative program. In view of the results obtained in the present study, we conclude that, for patients with previous experience in oral anticoagulation treatment, the educative strategy used was not efficient to improve the selected response variables. From the clinical viewpoint, this result is relevant for the health professionals who deliver care to this population of oral anticoagulation drug users. Our assertion is based on the knowledge produced in an earlier study by our research group, which found statistically significant and better results for the intervention group. When comparing the populations in both studies, which were undertaken at the same hospital, the sole difference relates to the length of the medication intake. Therefore, professionals should consider the usage length of the medication as a decisive factor in the choice of the educative strategy they will adopt
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Guo, Mei. "Exploring health behaviour determinants of ageing Australians with chronic diseases." Thesis, Queensland University of Technology, 2011. https://eprints.qut.edu.au/45939/1/Mei_Guo_Thesis.pdf.

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Background: Chronic disease presents overwhelming challenges to elderly patients, their families, health care providers and the health care system. The aim of this study was to explore a theoretical model for effective management of chronic diseases, especially type 2 diabetes mellitus and/or cardiovascular disease. The assumed theoretical model considered the connections between physical function, mental health, social support and health behaviours. The study effort was to improve the quality of life for people with chronic diseases, especially type 2 diabetes and/or cardiovascular disease and to reduce health costs. Methods: A cross-sectional post questionnaire survey was conducted in early 2009 from a randomised sample of Australians aged 50 to 80 years. A total of 732 subjects were eligible for analysis. Firstly, factors influencing respondents‘ quality of life were investigated through bivariate and multivariate regression analysis. Secondly, the Theory of Planned Behaviour (TPB) model for regular physical activity, healthy eating and medication adherence behaviours was tested for all relevant respondents using regression analysis. Thirdly, TPB variable differences between respondents who have diabetes and/or cardiovascular disease and those without these diseases were compared. Finally, the TPB model for three behaviours including regular physical activity, healthy eating and medication adherence were tested in respondents with diabetes and/or cardiovascular diseases using Structure Equation Modelling (SEM). Results: This was the first study combining the three behaviours using a TPB model, while testing the influence of extra variables on the TPB model in one study. The results of this study provided evidence that the ageing process was a cumulative effect of biological change, socio-economic environment and lifelong behaviours. Health behaviours, especially physical activity and healthy eating were important modifiable factors influencing respondents‘ quality of life. Since over 80% of the respondents had at least one chronic disease, it was important to consider supporting older people‘s chronic disease self-management skills such as healthy diet, regular physical activity and medication adherence to improve their quality of life. Direct measurement of the TPB model was helpful in understanding respondents‘ intention and behaviour toward physical activity, healthy eating and medication adherence. In respondents with diabetes and/or cardiovascular disease, the TPB model predicted different proportions of intention toward three different health behaviours with 39% intending to engage in physical activity, 49% intending to engage in healthy eating and 47% intending to comply with medication adherence. Perceived behavioural control, which was proven to be the same as self-efficacy in measurement in this study, played an important role in predicting intention towards the three health behaviours. Also social norms played a slightly more important role than attitude for physical activity and medication adherence, while attitude and social norms had similar effects on healthy eating in respondents with diabetes and/or cardiovascular disease. Both perceived behavioural control and intention directly predicted recent actual behaviours. Physical activity was more a volitional control behaviour than healthy eating and medication adherence. Step by step goal setting and motivation was more important for physical activity, while accessibility, resources and other social environmental factors were necessary for improving healthy eating and medication adherence. The extra variables of age, waist circumference, health related quality of life and depression indirectly influenced intention towards the three behaviours mainly mediated through attitude and perceived behavioural control. Depression was a serious health problem that reduced the three health behaviours‘ motivation, mediated through decreased self-efficacy and negative attitude. This research provided evidence that self-efficacy is similar to perceived behavioural control in the TPB model and intention is a proximal goal toward a particular behaviour. Combining four sources of information in the self-efficacy model with the TPB model would improve chronic disease patients‘ self management behaviour and reach an improved long-term treatment outcome. Conclusion: Health intervention programs that target chronic disease management should focus on patients‘ self-efficacy. A holistic approach which is patient-centred and involves a multidisciplinary collaboration strategy would be effective. Supporting the socio-economic environment and the mental/ emotional environment for older people needs to be considered within an integrated health care system.
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Adefolalu, Adegoke Olusegun. "Self-efficacy and beliefs about medications: implications for antiretroviral therapy adherence." Thesis, 2013. http://hdl.handle.net/10500/10571.

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The earlier optimism generated by the efficacy of antiretroviral drugs in human immuno-deficiency virus (HIV) patients has been dissipated in the face of the enormous chal-lenge of maintaining a nearly perfect adherence indefinitely. This study set to determine the influence of HIV adherence self-efficacy and beliefs about medicines on antiretrovi-ral therapy adherence, with the aim of developing a framework for enhancing antiretrovi-ral therapy (ART) adherence through focused intervention on modifiable factors from study variables that are strongly associated with ART adherence. A descriptive correlational design was used to assess the predictive relationships of HIV adherence Self-Efficacy, Beliefs about Medicines and ART adherence among 232 HIV-infected patients in a large public health facility in Pretoria. Participants' medication be-liefs were assessed using the Beliefs about Medicines Questionnaire, HIV adherence self-efficacy was assessed with HIV adherence self-efficacy scale (HIV-ASES) and ART adherence was assessed using the AIDS Clinical Trial Group questionnaire. Pearson correlation analysis was used to assess bivariate associations among the variables, and multiple regression analysis was used to examine the relationships among the inde-pendent variables and ART adherence. Mean adherence for the 232 participants was 95% (SD=13.2). Correlation analysis re-vealed positive bivariate associations between perceived general harm and overuse of medications, and ART adherence (p<0.05); between specific necessity and concerns about ARVs, and perceived general harm and overuse of medications (p<0.05); be-tween HIV adherence self efficacy and ART non-adherence (p<0.05). Multiple regres-sion analysis showed significance for perceived general harm and overuse of medica-tions on ART adherence (F(1;231)=11,583;p<0,001) with perceived general harmful ef-fects and overuse of medications explaining 4.8% of the variance. There was signifi-cance for HIV adherence self-efficacy on ART non-adherence (F(1;41)=4.440; p<0.041), with HIV-ASES explaining 9,8% of the variance. Based on the results, a framework for enhancing ART adherence was developed. Activities in the framework consist of baseline screening for adherence facilitators and barriers using the beliefs about medicine questionnaire and HIV ASES, this is followed by focused interventions on identified barriers of ART adherence
Health Studies
D.Litt. et Phil. (Health Studies)
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Lorenz, Tierney Kyle Ahrold. "Efficacy of an exercise intervention for sexual side effects of antidepressant medications in women." Thesis, 2013. http://hdl.handle.net/2152/26084.

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Antidepressants are associated with sexual side effects (Clayton, Keller, & McGarvey, 2006). Sexual side effects are associated with non-compliance or discontinuance of antidepressants (Werneke, Northey, & Bhugra, 2006). Despite this, there are few empirically supported treatments for antidepressant side effects. However, in laboratory studies, exercise immediately before sexual stimuli improved sexual arousal of women taking antidepressants (Lorenz & Meston, 2012). I evaluated if exercise improves sexual functioning in women experiencing antidepressant-induced sexual side effects. Fifty-two women reporting antidepressant sexual side effects were followed for 3 weeks of sexual activity only. They were randomized to complete either three weeks of exercise immediately before sexual activity (3x/week) or 3 weeks of exercise separate from sexual activity (3x/week). At the end of the first exercise arm, participants crossed to the other. I measured sexual functioning, sexual satisfaction, depression and physical health. Completers showed modest improvements in sexual functioning and satisfaction. For women taking selective serotonin and norepinephrine reuptake inhibitors, exercising immediately before sexual activity was superior to exercise in general. As well as known effects in improved physical and psychological health, exercise may help improve sexual health and pleasure in women taking antidepressants. These findings have important implications for public health, as exercise is accessible, cheap, and does not add to burden of care.
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Jhang, Kai-Ming, and 張凱茗. "Explore the efficacy and side effects of common medications in clinical neurology – using national health registry and insurance data." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/gxmw69.

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博士
中山醫學大學
公共衛生學系博士班
106
The present report use National Health Insurance Research Database (NHIRD) to explore the efficacy and side effects of common medications in clinical neurology. There are two main parts in this thesis. First part aimed to elucidate if long-term duration of aspirin and clopidogrel following carotid artery stenting (CAS) would provide an extra clinically relevant benefit. We concluded long-term (more than 42 days as compared with 30-42 days) use of aspirin plus clopidorel after CAS did not decrease the risk of ischemic stroke, composite vascular events or death during 6 months of follow up. The duration (1 month) suggested based on current guidelines is probably suitable. More researches are needed to provide more evidence on the appropriate duration of dual antiplatelet therapy after CAS. Second part investigated the incidence, occurrence time and risk factors of cinnarizine (cz) and flunarizine (fz)-related extrapyramidal side effects (EPSEs). The incidence rates of fz and cz-induced EPSEs were 21.03 and 10.3 per 10,000 person-months, respectively. The hazard ratios (HRs) of EPSEs among fz and cz subjects were 8.03 (95% CI 6.55-9.84) and 3.41 (95% CI 2.50-4.63) when compared with the control individuals. Higher exposure dose and duration, old age, history of essential tremor or cardiovascular disease increased the risk of fz-associated EPSEs. Potential risks should be weighed when considering long-term use of these drugs.
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Huang, Ting-Yu, and 黃亭瑜. "Impact of Tyrosine Kinase Inhibitors and Co-medications on the Efficacy of Patients with Advanced Non-small Cell Lung Cancer." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/39dv28.

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碩士
國立陽明大學
藥理學研究所
106
Tyrosine kinase inhibitors (TKIs) including gefitinib, erlotinib, afatinib and osimertinib are recommended as first-line therapy for patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR)-activating mutations. Gefitinib, erlotinib, and afatinib have been reimbursed by the National Health Insurance program for the first-line treatment of patients with stage IIIb or IV NSCLC with EGFR-activating mutations now. However, few studies compared these three TKIs together. Besides, previous studies showed specific medications such as hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins), metformin, acid-suppressing (AS) medications, and glucocorticoids might influence efficacy of TKIs. There was few large sample and well-conducted studies to confirm the impact of co-medications. Thus, we conducted a retrospective study using database of Taipei Veterans General Hospital to determine the efficacy of TKIs and impact of co-medications on survival.
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Chen-YuLin and 林貞余. "Effect of online objective structured video examination on promoting medicating self-efficacy and identifying medication errors in nurses." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/mnpnef.

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碩士
國立成功大學
護理學系
106
Nurses’ medication errors will affect the safety of patients, especially the five rights of and interruptions during medication administration. The aim of this project was to investigate the association between medication self-efficacy and identification of medication errors in nurses, and the effect of online objective structured video examination (OSVE) for promoting medication self-efficacy and identification of medication errors. A quasi-experimental, pretest-posttest design and internet survey was employed, and participants were recruited by using respondent-driven sampling (RDS). Results showed both medication self-efficacy and identification of medication errors’ posttest average scores were higher than pretest average scores. Gender was significantly correlated with medication self-efficacy. Marriage, nursing ladder, working unit had significant association with the pretest of identifying medication errors. By the paired samples t test, the pretest and posttest showed significant differences included medication self-efficacy and identification of medication errors. Findings from this study support that the medication OSVE education can improve identifying medication errors immediately and increase the medication self-efficacy. We inferred that OSVE can be an effective strategy of medication education.
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Zaharciuc, Luminita. "The impact of trust and self-efficacy on medication adherence." Master's thesis, 2020. http://hdl.handle.net/10071/21533.

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Pharmacy practice has shifted from one that is product- oriented towards one that is more patient-oriented, leading to an increased interest in pharmacist-patient interaction. In this way, it became necessary to understand the relationship between trust, self- efficacy and adherence to medication in a long-term patient-pharmacist relationship by adopting a social perspective. Thus, this study aim to provide more understandings about how trust and self-efficacy influence patients’ medication adherence behavior. Moreover, an exploratory and qualitative research will be approached to understand pharmacists and people’s view/opinion about patient/ pharmacists trusting-relationship and how people’s behavior is influenced when a trusting patient/pharmacists relationship exists. In this sense, a population approach was carried out by distributing questionnaires with open questions and by some structured interviews. It has been concluded that, patients’ medication adherence behavior is affected by the trust they place in a pharmacist, in cases of non-prescribed drugs and in the event of any irregularity in prescribed ones. Plus, patients’ self-efficacy beliefs and outcome expectancy also influence their medication adherence behavior and patients’ self-efficacy beliefs and outcome expectancy are influenced by their trust in a pharmacist. Pharmacists still have a way to go before they fully influence patients' behaviors. Interventions designed to enhance patients’ sense of self-efficacy for medication adherence, as well as patients’ trust in pharmacists, may be effective to detect adherence barriers and to settle non- adherence’s issues.
A prática farmacêutica tem estado mais orientada no cliente do que no produto, desencadeando um maior interesse pela relação entre o paciente e o farmacêutico. Portanto, tornou-se necessário compreender como a confiança, autoeficácia e adesão à medicação se relacionam nas interações entre o paciente e o farmacêutico, adotando uma perspetiva de análise social (Teoria Social Cognitiva). Assim sendo, este estudo tenciona reforçar os conhecimentos sobre como a confiança e a autoeficácia influência a adesão à medicação dos pacientes. Adotou-se uma pesquisa exploratória e qualitativa para entender a perspetivas dos farmacêuticos e das pessoas neste contexto. Foi feita uma distribuição pela população de questionários com questões abertas e algumas entrevistas estruturadas. Concluiu-se que o comportamento de adesão aos medicamentos dos pacientes é afetado pela confiança que depositam no farmacêutico (quando os medicamentos não são prescritos e quando os farmacêuticos detetam erros na prescrição), mas também pela autoeficácia e expectativa de resultado dos pacientes, sendo que estes são influenciados pela confiança no farmacêutico. Os farmacêuticos ainda têm um longo caminho a percorrer para influenciar totalmente o comportamento dos pacientes. Intervenções destinadas a aumentar o senso de autoeficácia dos pacientes para a adesão à medicação, bem como a confiança dos pacientes nos farmacêuticos, podem ser eficazes para detetar barreiras e resolver problemas no âmbito da adesão à medicação.
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Hsu, Hsin-Yun, and 許馨云. "Efficacy of Traditional Chinese Medication Supplementary Treatment for Breast Cancer Patients Chemotherapy." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/s893r6.

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碩士
義守大學
醫務管理學系
107
Breast cancer is the most common cancer among women worldwide, and it is also the highest cancer incidence among women in Taiwan. At present, chemotherapy is one of the common ways to treat breast cancer, but chemotherapy will inevitably cause damage to normal cells in the human body. Along with the advancement of medicine, the health care system in Taiwan is increasingly focusing on the integration of Western medicine and non-mainstream traditional medicine. Traditional Chinese medicine (TCM) plays an important role in extending the patients’ lives and improving their quality of life. Therefore, the present study aimed to investigate the changes of physiological indicators, nutritional status, quality of life, and life function for breast cancer patients who received TCM during chemotherapy, and to examine the effect of the changes of physiological indicators and nutritional status on the changes of their quality of life and life functions. This study used a retrospective study design and conducted secondary data analysis. The study participants were the breast cancer patients in a medical center in Kaohsiung City who received supplementary TCM during their chemotherapy in the period of April 2016 to December 2017. The study participants conducted pre-test before supplementary TCM and conducted post-test after 3 months of TCM. The measurement scale includes the Functional Assessment of Cancer Therapy (FACT-G), the Eastern Cooperative Oncology Group scale (ECOG), and various physiological indicators (BMI, white blood cells, heme, and platelets). The results showed that the breast cancer patients who received three months of TCM intervention during chemotherapy significantly improved their quality of life (t=8.10, p<0.001), including the physiological, social, emotional, and functional dimension. The TCM can also improve the life function of breast cancer patients (t = -5.48, p<0.001). In addition, the breast cancer patients whose white blood cells became worse during the intervention of TCM, their quality of life (b=-7.14, p=0.002) and life function (b=0.50, p=0.007) were also worse than other patients. The results of this study support the effectiveness of TCM for breast cancer patients during chemotherapy. We can promote the TCM intervention for breast cancer patients, and we must pay attention to the changes in white blood cells for breast cancer patients during chemotherapy.
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武氏艷翠. "RELATIONSHIP BETWEEN SELF-EFFICACY AND MEDICATION ADHERENCE ON PATIENTS WITH PERCUTANEOUS CORONARY INTERVENTION." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/qh3ag6.

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碩士
美和科技大學
護理系健康照護碩士班
107
Objectives: This is a cross-sectional study about relationship between self-efficacy and medication adherence on patients with percutaneous coronary intervention. The study uses validated Vietnamese version of Self-efficacy scale (SEAMS) and modified Morisky Green Levine Medication Adherence Scale (MGL). Method: The data were obtained from 385 patients (235 men 61.0% and 150 women 39.0%, mean age 66.41 ± 11.779 years), who was given the questionnaire at the outpatient clinic during their follow- up after PCI. Results: The findings have proved the reliability of the scales. Reliability of self-efficacy scale is Cronbach's Alpha = 0.957 and reliability of Medication adherence scale (seven-items) is Cronbach's Alpha = 0.689. Also in this result, demographic characteristics are age group, academic levels, avocation, economic status, self-care and dyslipidemia has an effect on self-efficacy with the value of p < 0.000. Patients’ demographic characteristics did not affected on the medication adherence (p > 0.05). The rate of medication adherence was 75.7% (n = 290) and non-adherence rate was 24.2% (n = 93) and high self-efficacy (n =291, 76.0%), low self-efficacy (n = 92, 24.0%). Conclusions: There is a positive correlation between the self-efficacy and medication adherence (r= 0.41). The p value verifying the significance of the coefficient R in this case is P < 0.001. The higher score of self-efficacy correlated with the better score of medication adherence.
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ZHAN, YI-LIANG, and 詹益亮. "Study on microencapsulation of enteric-coated mycoplasma hyopneumoniae oral vaccine and its medication efficacy." Thesis, 1991. http://ndltd.ncl.edu.tw/handle/63574679411123725155.

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37

Shubitz, Lisa, Michael E. Roy, David Nix, and John N. Galgiani. "Efficacy of Nikkomycin Z for respiratory coccidioidomycosis in naturally infected dogs." 2013. http://hdl.handle.net/10150/621447.

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Nikkomycin Z (NikZ) is a chitin synthase inhibitor with antifungal efficacy against Coccidioides spp. and other endemic fungi. Dogs suffer a rate and range of natural coccidioidomycosis similar to humans and were considered an excellent model for initially testing NikZ against naturally acquired disease. Twelve dogs with coccidioidal pneumonia that had been present for an average of three months were treated with 250 mg (5 - 15 kg) or 500 mg (> 15 - 30 kg) twice daily for 60 days. Nine dogs completed the course of treatment and seven dogs had improvement in disease based on radiographs, clinicopathological parameters, physical examination findings, and subjective assessment by the owners; three dogs had resolution or near resolution of disease. Based on this small study, NikZ shows efficacy to treat naturally acquired coccidioidomycosis and merits further development for trials in humans.
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38

Wright, C. Baker Bailey Jon S. "The efficacy of brief functional analysis procedures on assessing ADHD behaviors and the effect of stimulant medication." Diss., 2005. http://etd.lib.fsu.edu/theses/available/etd-04082005-160043.

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Thesis (Ph. D.)--Florida State University, 2005.
Advisor: Dr. Jon S. Bailey, Florida State University, College of Arts and Sciences, Dept. of Psychology. Title and description from dissertation home page (viewed June 16, 2005). Document formatted into pages; contains ix, 85 pages. Includes bibliographical references.
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39

Mountain, Brian W. "The efficacy of oral dexmedetomidine as an anesthetic pre-operative medication and as a deterrent to emergence delirium." 2008. http://etd.utk.edu/August2008MastersTheses/MountainBrianW.pdf.

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40

"A comparative study to determine the efficacy of chiropractic spinal manipulative therapy and allopathic medication in the treatment of infantile colic." Thesis, 2009. http://hdl.handle.net/10210/2640.

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41

Yang, Chueh-Hsuan, and 楊玨璿. "The Study of Medication Adherence in Outpatients with Hypertension in a Medical Center -- The Influence of Self-efficacy and Cues to action." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/43274949358246565427.

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碩士
國立臺灣大學
護理學研究所
97
The purposes of this study are to apply Becker’s health belief model(1974)and Bandura’s self-efficacy theory(1977) to exploring the medication adherence behaviors and relevant factors in out-patients with hypertension. The research subjects, who had received anti-hypertension treatment over 3 month, from cardiac clinics of a medical center in Taipei. The formal structured questionnaire was composed of patient’s basic informations, “Adherence behaviors scale”, “Health belief scale”, “Cues to action scale” and “Self-efficacy scale”. A total of 112 subjects were interviewed face-to-face. The results shown were as follows: 1.An objective definition of poor adherence to prescription was the score of “Adherence behavior scale” less than 4.557, and systolic blood pressure more than 140 mmHg or diastolic blood pressure more than 90 mmHg. According to this definition, the poor adherence rate was 7.1%, and adherence rate was 65.2%. 2.The main reason for subjects not taking their medications was forgetfulness. Their poor adherence behaviors included omissions of medication schedule, omissions of medication type and dose. 3.The self-efficacy had a significant correlation with medication adherence behaviors and also explained the 7.6% of total variation in subjects’ medication adherence behaviors. 4.The subjects’ age affected perceived severity、 perceived barriers of action and positive cues to action. The subjects’ education level affected perceived severity and perceived benefits of action. Conclusions: Bandura’s self-efficacy theory can be used to predic drug adherence behaviors of hypertension patients. Recommendations: (1) Nurses should emphasize the management of medication for forgetfulness;(2) Nurses can strengthen patient’s ability and confidence for medication adherence;(3) Nurses have to design the education plan of according to education level and age of hypertensive patients for medication education.
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42

Rodrigues, André Filipe Gomes. "Eficácia dos tratamentos nas dependências químicas." Master's thesis, 2019. http://hdl.handle.net/10437/10312.

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Orientação: Andreia de Moura
Neste estudo foi avaliada a correlação entre as variáveis envolvimento terapêutico e sintomatologia psicopatológica, nas suas diferentes dimensões. Adicionalmente, foi avaliado de que forma a variável duração em tratamento está associada a uma maior eficácia (i.e. quer parcial - indivíduo permanece abstinente ao consumo; quer global - para além da abstinência o indivíduo revela melhorias significativas em várias dimensões do seu funcionamento psicossocial). A amostra de 93 indivíduos, 84 do sexo masculino e 9 do sexo feminino, foi recolhida em programas de tratamento ambulatório na Divisão para a Intervenção nos Comportamentos Aditivos e Dependências (DICAD) com idades compreendidas entre os 23 e os 61 anos. Trata-se de uma amostra de conveniência. Este estudo é de design transversal, de carácter exploratório e descritivo, que não procura relações de causalidade para generalização dos resultados. Procura assim descrever variáveis e encontrar possíveis relações entre elas (correlacional). Utilizou-se um questionário Sócio Demográfico, para recolha de dados gerais, o Inventário de sintomas Psicopatológicos (BSI) e o instrumento Monotorização e Avaliação da Eficácia e do Progresso (MEEP) através dos quais se obtiveram-se os valores para a formação das variáveis a avaliar. Devido à lacuna verificada na literatura sobre a escassez de instrumentos e processos de avaliação de programas de intervenção em consumidores de substâncias químicas, que incluam o fator eficácia global, mostrou-se pertinente esta investigação neste âmbito. No presente estudo não se confirmaram as hipóteses, o que pode ter como razão explicativa a existência de variáveis que podem ter enviesado os nossos resultados e que não foram controladas, como por exemplo o fator estilo ou padrão de vinculação ou o fator motivação e crença no tratamento. Conclui-se que apesar dos nossos resultados não indicarem relações significativas entre as variáveis em estudo, esta área deve ser investigada através de estudos longitudinais e amostras mais robustas.
In this study, it was evaluated the correlation between the variables therapeutic envolvment and psicopathological symptomatology, in their different dimensions. Addicionally, it was evaluated in wish way the variables’ duration in treatment is associated with a higher efficacy (i.e. Partially - the individual remains in drug abstinence; globally - beyond the abstinence, the individual shows significant improvements in some dimensions of its psycossocial functioning). The sample of 93 individuals, 84 are male and 9 are female, was gathered in programs of outpatient treatment of DICAD, with ages between 23 years and 61 years, being a convenience sample. This study is transversal, explorative and descriptive, and it doesn’t seek causal relations, for generalization of results. It describes variaties and finds possível links between them (correlation). A socio-demographic questionnaire was used to collect general data, the Psycopathological Sympton Inventory (BSI) and the Effectiveness and Progress monitoring and Evaluation (MEEP). These instruments gave the results to form the variables to evaluate. Due to the lack of evaluation of chemical consumer intervention programs, which include the global effectiveness factor, this research has shown to be important to the subject. In this study, it wasn’t possible to confirm the hipothesis, due to the fact that it some of the variables aren’t being accounted for, for example, style or binding pattern or belief in healing. Although the results in this study do not indicate significant relationships among the variables under study this area should be investigated through longitudinal studies and more robust samples.
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43

Nogueira, Rui Manuel Antunes. "Análise da automedicação em Portugal e seus intervenientes." Master's thesis, 2011. http://hdl.handle.net/10071/4680.

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A automedicação é uma prática cada vez mais comum e reconhece-se que o acesso à Farmácia para a automedicação é uma prática em crescendo em Portugal, muitas das vezes devido à falta de resposta efectiva do Sistema Nacional de Saúde para suportar a procura por parte das pessoas com problemas de saúde. O presente estudo foca a forma como o utente encara a automedicação, correlacionando vários conceitos: frequência da automedicação a confiança no farmacêutico, a atitude face aos medicamentos não sujeitos a receita médica, a auto-eficácia e a auto-regulação. Com base numa amostra de 168 indivíduos, os resultados obtidos mostram que não existe uma relação entre a automedicação e a confiança no farmacêutico (β = -0,055; p = 0,464), confiança nos medicamentos não sujeitos a receita médica (MNSRM) (β = 0,065; p = 0,404) e na auto-eficácia (β = -0,124; p = 0,109), mas existe uma relação muito forte entre a automedicação e a motivação, demonstrando-se que quanto mais elevado é o valor da motivação autónoma (β = 0,433; p = 0,000) maior é a tendência para a automedicação, e quanto mais alto é o valor da motivação controlada (β = -0,376; p = 0,000) menor é a tendência para a automedicação.
Self-medication is an increasingly common practice and it is acknowledged that the access to the pharmacy for self-medication is a growing practice in Portugal, often due to lack of effective response from the National Health System to support the demand from people with health problems. This study focuses on how a user faces the self-medication, trying to correlate various concepts: self-medications, trust on the pharmaceutics, attitudes towards drugs not subjected to medical prescription, self-efficacy and self-regulation. Based on a sample of 168 individuals, the obtained results show no relation between self-medication and the trust in the pharmacist (β = -0,055; p = 0,464), the trust in drugs not subjected to medical prescription (β = 0,065; p = 0,404) and the self-efficacy (β = -0,124; p = 0,109), but there is a very strong relation between self-medication and motivation; this study shows that the higher is the value of autonomous motivation (β = 0,433; p = 0,000) the higher is the tendency to self-medication, and the higher is the value of controlled motivation (β = -0,376; p = 0,000) the smaller is the tendency to self-medication.
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44

Teixeira, Jéssica Maria Antunes. "Relacionamento entre a confiança e a adesão à medicação: o efeito mediador da autoeficácia a da expetativa de resultado." Master's thesis, 2017. http://hdl.handle.net/10071/16475.

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Tendo em conta as mudanças constantes do dia-a-dia, é necessário tentar percebe-las e identificar em que ponto afetam as nossas vidas. Assim sendo, tornou-se necessário perceber até que ponto é que determinado órgão da saúde, nomeadamente o setor farmacêutico, influencia a autoeficácia e os comportamentos dos pacientes, mais especificamente o comportamento da tomada da medicação. A metodologia da investigação passa pela caracterização dos comportamentos de pacientes, pela elaboração dos seus perfis através da análise estatística dos questionários desenvolvidos. Concluiu-se que os farmacêuticos fazem com que o paciente acredite que consegue estabelecer mecanismos que o façam tomar a medicação contudo, a confiança não é suficientemente forte para o influenciarem a tomar efetivamente o medicamento. O mesmo acontece com a expetativa de resultado, o farmacêutico influencia-a, mas a confiança não é suficientemente forte para o influenciarem na ação de adesão à medicação. Também se concluiu que o facto de um paciente acreditar que consegue tomar a medicação e ter presente as consequências desse ato, influencia os comportamentos premeditados. Esta tese foi importante para os intervenientes do setor farmacêutico perceberem que ainda têm um longo caminho a percorrer para ganhar a confiança total do paciente, bem como o paciente tem de ter mais presente as consequências do comportamento da não tomada da medicação.
Taking into account the constant changes of daily life, it is necessary to try to understand and identify them, and understand which point they influence our lives. Giving this, it becomes necessary to understand at which point a certain health sector, mainly pharmaceutical, influence the self efficacy and patients’ behavior – more precisely the medication address. The investigation’s methodology goes from the characterization of patients’ behavior, elaboration of their profiles through the statistical analysis of the surveys developed. We conclude that pharmacists, do that the patient believe that its possible to establish mechanisms that makes him to take the medication, however the trust is not strong enough to influence him to take it. The same happen with the outcome expectation, the pharmacist influence it, but the trust is not strong enough to influence it in taking the medication. We also conclude that the fact that a patient believe that he can take the medication and have in presence the consequences of such an act influence the premeditated behaviors. This thesis was important for pharmaceutical stakeholders to realize that they still have a long way to go to gain full patient confidence, and the patient has to be more aware of the consequences of non-medication behavior.
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