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1

Tsuda, K., and M. Tanaka. "Nanometer Crystal Structure Analysis by EF-CBED and EF-Microscopy." Microscopy and Microanalysis 6, S2 (2000): 152–53. http://dx.doi.org/10.1017/s1431927600033250.

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Crystal structure refinement by the convergent-beam electron diffraction (CBED) method has the following advantages: (i) Nanometer-size crystal structure refinement: CBED patterns can be obtained from specimen areas of a few nanometer in diameter, (ii) Dynamical diffraction effect: the CBED intensities contain phase information of crystal structure factors through the strong dynamical effect. (iii) Site-selective analysis: the use of Bloch states formed by incident electrons allows structure determination weighted for specific atom sites. Energy-filtering (EF) to revome inelastically scattered
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2

Merve Çağlar, N., and Erdal Şafak. "Energy Flux Approach for Dynamic Analysis of Structures." Bulletin of the Seismological Society of America 109, no. 5 (2019): 1797–811. http://dx.doi.org/10.1785/0120180311.

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Abstract Dynamic response of structures can be analyzed in terms of the propagation of input energy within the structure. Energy propagation is quantified by energy flux (EF), which is the amount of energy transmitted per unit time through a cross section of a medium. The formulation of EF is similar to the formulation of wave propagation in structures. It involves tracking the propagation path of the input energy and the energy loss due to damping within the elements of the structure. The EF approach introduces a new tool to evaluate the dynamic response and the energy absorption capacity of
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3

Wang, Yong, Youxing Jiang, Martina Meyering-Voss, Mathias Sprinzl, and Paul B. Sigler. "Crystal structure of the EF-Tu˙EF-Ts complex from Thermus thermophilus." Nature Structural Biology 4, no. 8 (1997): 650–56. http://dx.doi.org/10.1038/nsb0897-650.

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4

Anderson Jnr, A. G., S. C. Critchlow, L. C. Andrews, and R. D. Haddock. "Structure of dicyclopenta[ef,kl]heptalene (azupyrene)." Acta Crystallographica Section C Crystal Structure Communications 46, no. 3 (1990): 439–41. http://dx.doi.org/10.1107/s0108270189007857.

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5

Mondal, Dibyendu, and Arieh Warshel. "EF-Tu and EF-G are activated by allosteric effects." Proceedings of the National Academy of Sciences 115, no. 13 (2018): 3386–91. http://dx.doi.org/10.1073/pnas.1800054115.

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Many cellular processes are controlled by GTPases, and gaining quantitative understanding of the activation of such processes has been a major challenge. In particular, it is crucial to obtain reliable free-energy surfaces for the relevant reaction paths both in solution and in GTPases active sites. Here, we revisit the energetics of the activation of EF-G and EF-Tu by the ribosome and explore the nature of the catalysis of the GTPase reaction. The comparison of EF-Tu to EF-G allows us to explore the impact of possible problems with the available structure of EF-Tu. Additionally, mutational ef
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6

Nizhnichenko, Vladimir A., Alexey V. Boyko, Talia T. Ginanova, and Igor Yu Dolmatov. "Muscle Regeneration in Holothurians without the Upregulation of Muscle Genes." International Journal of Molecular Sciences 23, no. 24 (2022): 16037. http://dx.doi.org/10.3390/ijms232416037.

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The holothurian Eupentacta fraudatrix is capable of fully restoring its muscles after transverse dissection. Although the regeneration of these structures is well studied at the cellular level, the molecular basis of the process remains poorly understood. To identify genes that may be involved in the regulation of muscle regeneration, the transcriptome of the longitudinal muscle band of E. fraudatrix has been sequenced at different time periods post-injury. An analysis of the map of biological processes and pathways has shown that most genes associated with myogenesis decrease their expression
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7

Kawashima, Takemasa, Carmen Berthet-Colominas, Michael Wulff, Stephen Cusack, and Reuben Leberman. "The structure of the Escherichia coli EF-Tu· EF-Ts complex at 2.5 Å resolution." Nature 379, no. 6565 (1996): 511–18. http://dx.doi.org/10.1038/379511a0.

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8

Nordenswan, Elisabeth, Eeva-Leena Kataja, Kirby Deater-Deckard, et al. "Latent Structure of Executive Functioning/Learning Tasks in the CogState Computerized Battery." SAGE Open 10, no. 3 (2020): 215824402094884. http://dx.doi.org/10.1177/2158244020948846.

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This study tested whether executive functioning (EF)/learning tasks from the CogState computerized test battery show a unitary latent structure. This information is important for the construction of composite measures on these tasks for applied research purposes. Based on earlier factor analytic research, we identified five CogState tasks that have been labeled as EF/learning tasks and examined their intercorrelations in a new sample of Finnish birth cohort mothers ( N = 233). Using confirmatory factor analyses, we compared two single-factor EF/learning models. The first model included the rec
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9

Himi, Samsad Afrin, Markus Bühner, and Sven Hilbert. "Advancing the Understanding of the Factor Structure of Executive Functioning." Journal of Intelligence 9, no. 1 (2021): 16. http://dx.doi.org/10.3390/jintelligence9010016.

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There has been considerable debate and interest regarding the factor structure of executive functioning (EF). Therefore, the aim of the current study was to delve into this issue differently, by investigating EF and other cognitive constructs, such as working memory capacity (WMC), relational integration, and divided attention, which may contribute to EF. Here, we examined whether it is possible to provide evidence for a definite model of EF containing the components of updating, shifting, and inhibition. For this purpose, 202 young adults completed a battery of EF, three WMC tests, three rela
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10

Hirano, Yu, Kana Tsukamoto, Shingo Ariki, Yuki Naka, Mitsuhiro Ueda та Taro Tamada. "X-ray crystallographic structural studies of α-amylase I from Eisenia fetida". Acta Crystallographica Section D Structural Biology 76, № 9 (2020): 834–44. http://dx.doi.org/10.1107/s2059798320010165.

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The earthworm Eisenia fetida possesses several cold-active enzymes, including α-amylase, β-glucanase and β-mannanase. E. fetida possesses two isoforms of α-amylase (Ef-Amy I and II) to digest raw starch. Ef-Amy I retains its catalytic activity at temperatures below 10°C. To identify the molecular properties of Ef-Amy I, X-ray crystal structures were determined of the wild type and of the inactive E249Q mutant. Ef-Amy I has structural similarities to mammalian α-amylases, including the porcine pancreatic and human pancreatic α-amylases. Structural comparisons of the overall structures as well a
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11

Djernæs, Marie, and Jakob Damgaard. "Exon-intron structure, paralogy and sequenced regions of elongation factor-1 alpha in Hexapoda." Arthropod Systematics & Phylogeny 64, no. 1 (2006): 45–52. http://dx.doi.org/10.3897/asp.64.e31643.

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Elongation factor-1 alpha (EF-1α) is already widely used and shows even more promise for phylogenetic studies of Hexapoda. However, paralogous copies and the presence of introns pose problems. We survey exon-intron structure, presence of paralogous copies and the number and extent of sequenced regions in all hexapod orders. We assess the phylogenetic utility of the exon-intron structure of EF-1α, which is unexpectedly dynamic with widespread losses and several independent instances of intron gain. Paralogous copies of EF-1α are present in Hemiptera, Thysanoptera, Neuropterida, Coleoptera, Hyme
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12

Djernæs, Marie, and Jakob Damgaard. "Exon-intron structure, paralogy and sequenced regions of elongation factor-1 alpha in Hexapoda." Arthropod Systematics & Phylogeny 64 (October 30, 2006): 45–52. https://doi.org/10.3897/asp.64.e31643.

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Elongation factor-1 alpha (EF-1α) is already widely used and shows even more promise for phylogenetic studies of Hexapoda. However, paralogous copies and the presence of introns pose problems. We survey exon-intron structure, presence of paralogous copies and the number and extent of sequenced regions in all hexapod orders. We assess the phylogenetic utility of the exon-intron structure of EF-1α, which is unexpectedly dynamic with widespread losses and several independent instances of intron gain. Paralogous copies of EF-1α are present in Hemiptera, Thysanoptera, Neuropterida, Coleoptera, Hyme
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13

Gagnon, Matthieu G., Jinzhong Lin, and Thomas A. Steitz. "Elongation factor 4 remodels the A-site tRNA on the ribosome." Proceedings of the National Academy of Sciences 113, no. 18 (2016): 4994–99. http://dx.doi.org/10.1073/pnas.1522932113.

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During translation, a plethora of protein factors bind to the ribosome and regulate protein synthesis. Many of those factors are guanosine triphosphatases (GTPases), proteins that catalyze the hydrolysis of guanosine 5′-triphosphate (GTP) to promote conformational changes. Despite numerous studies, the function of elongation factor 4 (EF-4/LepA), a highly conserved translational GTPase, has remained elusive. Here, we present the crystal structure at 2.6-Å resolution of the Thermus thermophilus 70S ribosome bound to EF-4 with a nonhydrolyzable GTP analog and A-, P-, and E-site tRNAs. The struct
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14

Wray, Charlotte, Alysse Kowalski, Feziwe Mpondo, et al. "Executive functions form a single construct and are associated with schooling: Evidence from three low- and middle- income countries." PLOS ONE 15, no. 11 (2020): e0242936. http://dx.doi.org/10.1371/journal.pone.0242936.

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Measuring executive function (EF) among adults is important, as the cognitive processes involved in EF are critical to academic achievement, job success and mental health. Current evidence on measurement and structure of EF largely come from Western, Educated, Industrialized, Rich and Democratic (WEIRD) countries. However, measuring EF in low-and-middle-income countries (LMICs) is challenging, because of the dearth of EF measures validated across LMICs, particularly measures that do not require extensive training, expensive equipment, or professional administration. This paper uses data from t
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15

CRISAN, V., A. VERNES, V. POPESCU, L. DULCA, and D. KAPUSI. "ELECTRONIC STRUCTURE OF YBa2(Cu1−xFex)3O7." International Journal of Modern Physics B 07, no. 01n03 (1993): 170–73. http://dx.doi.org/10.1142/s021797929300038x.

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The density of states (DOS) at the Fermi level, (EF), for the 123 superconductor doped with iron was computed. The LCAO model hamiltonian and the Haydock recursive method were used. The iron atoms were located only in one of the copper atom positions Cu1 or Cu2 or in both of them with the same probability. The substitution of Fe in Cu1 positions increased the DOS at the Fermi level as x increased but the substitutions in the Cu2 positions had an opposite effect. In both cases the O2 and O3 positions are inequivalent. When the replacement of copper atoms is produced with the same probability in
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16

Kawashima, Takemasa, Carmen Berthet-Colominas, Michael Wulff, Stephen Cusack, and Reuben Leberman. "Correction: The structure of the Escherichia coli EF-Tu. EF-Ts complex at 2.5 Å resolution." Nature 381, no. 6578 (1996): 172. http://dx.doi.org/10.1038/381172b0.

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17

Samsonova, M. G., S. G. Inge-Vechtomov, and P. Taylor. "Structure comparison and evolutionary relations between elongation factors EF-Tu (EF-1?) and SUP 2 proteins." Genetica 85, no. 1 (1991): 35–44. http://dx.doi.org/10.1007/bf00056104.

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18

Jang, Hyunseok, Sunghark Kwon, Chang-Sook Jeong, et al. "Structural analysis of a novel substrate-free form of the aminoglycoside 6′-N-acetyltransferase from Enterococcus faecium." Acta Crystallographica Section F Structural Biology Communications 76, no. 8 (2020): 364–71. http://dx.doi.org/10.1107/s2053230x20009735.

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Aminoglycoside acetyltransferases (AACs) catalyze the transfer of an acetyl group between acetyl-CoA and an aminoglycoside, producing CoA and an acetylated aminoglycoside. AAC(6′)-Ii enzymes target the amino group linked to the 6′ C atom in an aminoglycoside. Several structures of the AAC(6′)-Ii from Enterococcus faecium [Ef-AAC(6′)-Ii] have been reported to date. However, the detailed mechanism of its enzymatic function remains elusive. In this study, the crystal structure of Ef-AAC(6′)-Ii was determined in a novel substrate-free form. Based on structural analysis, it is proposed that Ef-AAC(
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19

Wei, Guoke, Jinliang Wang, and Yu Chen. "Electromagnetic enhancement of ordered silver nanorod arrays evaluated by discrete dipole approximation." Beilstein Journal of Nanotechnology 6 (March 9, 2015): 686–96. http://dx.doi.org/10.3762/bjnano.6.69.

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The enhancement factor (EF) of surface-enhanced Raman scattering (SERS) from two-dimensional (2D) hexagonal silver nanorod (AgNR) arrays were investigated in terms of electromagnetic (EM) mechanism by using the discrete dipole approximation (DDA) method. The dependence of EF on several parameters, i.e., structure, length, excitation wavelength, incident angle and polarization, and gap size has been investigated. “Hotspots” were found distributed in the gaps between adjacent nanorods. Simulations of AgNR arrays of different lengths revealed that increasing the rod length from 374 to 937 nm (asp
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20

Han, Yong, Bingjia Wei, Xiaoqiang Guo, and Tifeng Jiao. "Influence of Electrostatic Field on Mixed Aqueous Solution of Calcium and Ferrous Ions: Insights from Molecular Dynamics Simulations." Coatings 12, no. 8 (2022): 1165. http://dx.doi.org/10.3390/coatings12081165.

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In order to investigate the anti-scaling and anti-corrosion characteristics of an electrostatic anti-fouling system in the application process, the influence of an electrostatic field (EF) on the structure and dynamics of hydrated Ca2+ and hydrated Fe2+ in a mixed aqueous system was studied through the calculation and analysis of the radial distribution function (RDF), self-diffusion coefficients, viscosity, and hydrogen bond structure by using molecular dynamics simulation. The study results show that the EF can decrease the radius of the first water shell of hydrated Ca2+ but increase that o
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21

Li, James J., Tammy A. Chung, Michael M. Vanyukov, D. Scott Wood, Robert Ferrell, and Duncan B. Clark. "A Hierarchical Factor Model of Executive Functions in Adolescents: Evidence of Gene-Environment Interplay." Journal of the International Neuropsychological Society 21, no. 1 (2014): 62–73. http://dx.doi.org/10.1017/s1355617714001039.

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AbstractExecutive functions (EF) are a complex set of neurodevelopmental, higher-ordered processes that are especially salient during adolescence. Disruptions to these processes are predictive of psychiatric problems in later adolescence and adulthood. The objectives of the current study were to characterize the latent structure of EF using bifactor analysis and to investigate the independent and interactive effects of genes and environments on EF during adolescence. Using a representative young adolescent sample, we tested the interaction of a polymorphism in the serotonin transporter gene (5
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22

Gifford, Jessica L., Michael P. Walsh, and Hans J. Vogel. "Structures and metal-ion-binding properties of the Ca2+-binding helix–loop–helix EF-hand motifs." Biochemical Journal 405, no. 2 (2007): 199–221. http://dx.doi.org/10.1042/bj20070255.

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The ‘EF-hand’ Ca2+-binding motif plays an essential role in eukaryotic cellular signalling, and the proteins containing this motif constitute a large and functionally diverse family. The EF-hand is defined by its helix–loop–helix secondary structure as well as the ligands presented by the loop to bind the Ca2+ ion. The identity of these ligands is semi-conserved in the most common (the ‘canonical’) EF-hand; however, several non-canonical EF-hands exist that bind Ca2+ by a different co-ordination mechanism. EF-hands tend to occur in pairs, which form a discrete domain so that most family member
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23

Gao, Yonggui. "Structural basis of bacterial protein translation elongation." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C199. http://dx.doi.org/10.1107/s2053273314098003.

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Recently, better understanding of ribosome function has been achieved through structural determination. These results provided a wealth of information on how genetic codes are precisely translated into proteins that control life, as well as established the platform to put ribosome as one of the richest validated targets for antibacterial drug discovery. We discovered a new ribosome crystal form obtained from ribosome lacking subunit L9, which allows crystallization of the ribosome in the presence of elongation factors Tu and G (EF-Tu/EF-G), trapped by antibiotics kirromycin and fusidic acid, r
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24

Sanders, J., M. Brandsma, G. M. Janssen, J. Dijk, and W. Moller. "Immunofluorescence studies of human fibroblasts demonstrate the presence of the complex of elongation factor-1 beta gamma delta in the endoplasmic reticulum." Journal of Cell Science 109, no. 5 (1996): 1113–17. http://dx.doi.org/10.1242/jcs.109.5.1113.

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The eukaryotic elongation factor-1 (EF-1) consists of four subunits, EF-1 alpha, EF-1 beta, EF-1 gamma and EF-1 delta which induce efficient transfer of aminoacyl-tRNA to the ribosome. In this process EF-1 alpha.GTP acts as the carrier of the aminoacyl-tRNA on its way to the ribosome. After release of aminoacyl-tRNA to the ribosome under concomitant hydrolysis of GTP, the inactive EF-1 alpha.GDP form is recycled to EF-1 alpha.GTP by EF-1 beta gamma delta. In eukaryotic cells the concentration of EF-1 alpha exceeds that of the complex beta gamma delta by a factor of 5–10. In order to delineate
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25

Andrievskiĭ, V. V., Yu F. Komnik, and S. V. Rozhok. "Fine structure of the transverse electron focusing lines in bismuth. II. Relaxation effects." Low Temperature Physics 22, no. 12 (1996): 1076–83. https://doi.org/10.1063/10.0034161.

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It is shown that the shape of the electron focusing (EF) line and its fine structure reflect electron relaxation processes in the point contact region under the conditions of strong emitter currents. The relaxation of highly nonequilibrium electrons due to emission of nonequilibrium phonons (predominantly longitudinal optical phonons) is identified on the EF line in a Bi crystal, and an effective relaxation process associated with excitation of a collective vibrational mode with a characteristic energy ∼40 meV is observed. The fine structure of the EF line also reflects interference effects in
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26

Komnik, Yu F., V. V. Andrievskii, and S. V. Rozhok. "Fine structure of the transverse electron focusing lines in bismuth. I. Quantum effects." Low Temperature Physics 22, no. 12 (1996): 1066–75. https://doi.org/10.1063/10.0034160.

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It is shown that the fine structure of the transverse electron focusing (EF) line in a Bi crystal is determined by diffraction of the electron flow injected into the crystal through a point contact. The ballistic transport of electrons in the EF method preserves nonuniform angular distribution of electrons undergoing diffraction on the cyclotron trajectory. This distribution is manifested in the form of additional peaks against the background of the first EF line. The position of the peaks and their shift in the magnetic field upon a change in the electron energy correspond to the results of c
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27

Luo, Haiqiong, Wei Lan, Qingfeng Chen, et al. "Inferring microRNA-Environmental Factor Interactions Based on Multiple Biological Information Fusion." Molecules 23, no. 10 (2018): 2439. http://dx.doi.org/10.3390/molecules23102439.

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Accumulated studies have shown that environmental factors (EFs) can regulate the expression of microRNA (miRNA) which is closely associated with several diseases. Therefore, identifying miRNA-EF associations can facilitate the study of diseases. Recently, several computational methods have been proposed to explore miRNA-EF interactions. In this paper, a novel computational method, MEI-BRWMLL, is proposed to uncover the relationship between miRNA and EF. The similarities of miRNA-miRNA are calculated by using miRNA sequence, miRNA-EF interaction, and the similarities of EF-EF are calculated bas
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28

Wulanyani, Ni Made Swasti, Lucia Trisni Widhianingtanti, Aria Saloka Immanuel, et al. "Psychometric properties of the Five-executive Function Tests in Indonesian samples." Psikohumaniora: Jurnal Penelitian Psikologi 9, no. 1 (2024): 125–46. http://dx.doi.org/10.21580/pjpp.v9i1.20957.

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Difficulties in executive function (EF) may be causative factors in clinical conditions, including learning disabilities, depression, and anxiety. However, defining the structure of EF is an ongoing issue, although Miyake’s three-factor structure is widely accepted. This study aims to discover the underlying factor structure of EF domains, as measured by five tests and the scores of 840 participants, to establish the domains’ validity and reliability. Five neuropsychological tests were included in the exploratory and confirmatory factor analyses (EFA and CFA): the Digit Span (DS); the Stroop C
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29

Kenworthy, Lauren, Andrew Freeman, Allison Ratto, et al. "Preliminary Psychometrics for the Executive Function Challenge Task: A Novel, “Hot” Flexibility, and Planning Task for Youth." Journal of the International Neuropsychological Society 26, no. 7 (2020): 725–32. http://dx.doi.org/10.1017/s135561772000017x.

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AbstractObjective:Executive functions (EF) drive health and educational outcomes and therefore are increasingly common treatment targets. Most treatment trials rely on questionnaires to capture meaningful change because ecologically valid, pediatric performance-based EF tasks are lacking. The Executive Function Challenge Task (EFCT) is a standardized, treatment-sensitive, objective measure which assesses flexibility and planning in the context of provocative social interactions, making it a “hot” EF task.Method:We investigate the structure, reliability, and validity of the EFCT in youth with a
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Wang, Zhen Hui, Qing Feng Zeng, Feng Xia Guo, Dong Pu Xu, and Hao Wang. "A Study of the Electrostatic Field Networking in Three Isolated Thunderstorms." Applied Mechanics and Materials 239-240 (December 2012): 775–84. http://dx.doi.org/10.4028/www.scientific.net/amm.239-240.775.

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This work presents an analysis of atmospheric electrostatic field (EF) networking using radar and sounding data base on a quasi-normal charge distribution model in isolated storm cells. The charge distribution parameters of the thundercloud are first estimated and inversed with the model, and then the networked EF of the ground can be recalculated using the obtained parameters. The method was used to analyze three isolated thunderstorms that passed through the experiment site in 2009. It was found that the EF networking and the charge distribution were concordant with the location of lightning
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31

Tuckwell, D. S., A. Brass, and M. J. Humphries. "Homology modelling of integrin EF-hands. Evidence for widespread use of a conserved cation-binding site." Biochemical Journal 285, no. 1 (1992): 325–31. http://dx.doi.org/10.1042/bj2850325.

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Integrin alpha-subunits contain three or four peptide sequences that are similar to the EF-hand, a 13-residue bivalent cation-binding motif found in calmodulin and parvalbumin. The integrin sequences differ from classical EF-hands in that they lack a co-ordinating residue at position 12. One hypothesis to explain integrin-ligand binding is that aspartate-containing recognition sequences in integrin ligands, which bind at or near to the EF-hand-like sequences, may take the place of the missing residue and co-ordinate directly to the bound cation. In this report, homology modelling of integrin E
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32

Yadira, Agung, T. Thyrhaya Zein, and Eddy Setia. "The Analysis Schematic Structure of Research Article from Journal Indexed by Sinta." East Asian Journal of Multidisciplinary Research 1, no. 5 (2022): 825–42. http://dx.doi.org/10.55927/eajmr.v1i5.572.

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This study analyzes the schematic structure of Sinta's indexed research articles. The object of this research is in the form of fifteen indexed research articles of Sinta ranked 1 and 2. The schematic structure of this research article is then analyzed using SLF theory because this study is a study of the SFL genre. The researcher integrates the concept of Huang & Chen (2018). In conducting data analysis, this study adapted the interactive model of Miles, Huberman & Saldana (2014). It was found in this study that there are two structures in the research article, namely the mandatory st
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33

Kim, Min-Kyu, Ji-Hye Kim, Ji-Sun Kim, and Sa-Ouk Kang. "Structure of the 34 kDa F-actin-bundling protein ABP34 fromDictyostelium discoideum." Acta Crystallographica Section D Biological Crystallography 71, no. 9 (2015): 1835–49. http://dx.doi.org/10.1107/s139900471501264x.

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The crystal structure of the 34 kDa F-actin-bundling protein ABP34 fromDictyostelium discoideumwas solved by Ca2+/S-SAD phasing and refined at 1.89 Å resolution. ABP34 is a calcium-regulated actin-binding protein that cross-links actin filaments into bundles. Itsin vitroF-actin-binding and F-actin-bundling activities were confirmed by a co-sedimentation assay and transmission electron microscopy. The co-localization of ABP34 with actin in cells was also verified. ABP34 adopts a two-domain structure with an EF-hand-containing N-domain and an actin-binding C-domain, but has no reported overall s
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34

Wu, Decun, and Jinping Liu. "Threshold Effects of Restraining Factors on China’s Provincial Ecological Footprint in the Process of Urbanization." International Journal of Environmental Research and Public Health 17, no. 7 (2020): 2407. http://dx.doi.org/10.3390/ijerph17072407.

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This study uses a panel threshold model to explore the nonlinear relationship between restraining factors and ecological footprint (EF) evolution from 2003 to 2015 in China. In addition, the heterogeneity of the environmental Kuznets curve (EKC) hypothesis is identified. The results show that the four regime-dependent variables, i.e., technology level, openness, industrial structure and energy efficiency, have significant single-threshold effects on the EF in China, and the negative correlations between these variables and EF are significantly enhanced when the threshold variable urbanization
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35

Chen, Yun, Shu Feng, Veerendra Kumar, Rya Ero, and Yong-Gui Gao. "Structure of EF-G–ribosome complex in a pretranslocation state." Nature Structural & Molecular Biology 20, no. 9 (2013): 1077–84. http://dx.doi.org/10.1038/nsmb.2645.

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36

Ekblad, Bie, Panagiota K. Kyriakou, Camilla Oppegård, Jon Nissen-Meyer, Yiannis N. Kaznessis, and Per Eugen Kristiansen. "Structure–Function Analysis of the Two-Peptide Bacteriocin Plantaricin EF." Biochemistry 55, no. 36 (2016): 5106–16. http://dx.doi.org/10.1021/acs.biochem.6b00588.

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37

Okazaki, H., T. Yokoya, J. Nakamura, et al. "Near EF electronic structure of heavily boron-doped superconducting diamond." Journal of Physics and Chemistry of Solids 69, no. 12 (2008): 2978–81. http://dx.doi.org/10.1016/j.jpcs.2008.06.006.

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38

Miloushev, Vesselin Z., Joshua A. Levine, Mark A. Arbing, John F. Hunt, Geoffrey S. Pitt, and Arthur G. Palmer. "Solution Structure of the NaV1.2 C-terminal EF-hand Domain." Journal of Biological Chemistry 284, no. 10 (2009): 6446–54. http://dx.doi.org/10.1074/jbc.m807401200.

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39

Kjeldgaard, Morten, and Jens Nyborg. "Refined structure of elongation factor EF-Tu from Escherichia coli." Journal of Molecular Biology 223, no. 3 (1992): 721–42. http://dx.doi.org/10.1016/0022-2836(92)90986-t.

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40

Zheng, Chunlei, Hui-hui Liu, Jiahai Zhou, and Bin Zhang. "EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII." Blood 115, no. 5 (2010): 1081–87. http://dx.doi.org/10.1182/blood-2009-09-241877.

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Abstract Combined deficiency of factor V and factor VIII (F5F8D) is a bleeding disorder caused by mutations in either LMAN1 or MCFD2. LMAN1 (ERGIC-53) and MCFD2 form a Ca2+-dependent cargo receptor that cycles between the endoplasmic reticulum (ER) and the ER-Golgi intermediate compartment for efficient transport of FV/FVIII from the ER to the Golgi. Here we show that the C-terminal EF-hand domains are both necessary and sufficient for MCFD2 to interact with LMAN1. MCFD2 with a deletion of the entire N-terminal non-EF hand region still retains the LMAN1-binding function. Deletions that disrupt
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41

Ansari, M. "Implications of One-Loop Quantum Correction in the Background Geometry of 5-Dimensional Kaluza-Klein Cosmology." Journal of the Tensor Society 4, no. 01 (2007): 77–86. http://dx.doi.org/10.56424/jts.v4i01.10421.

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Through dimensional reduction and one-loop quantum correction of scalar and spinor fields, time-dependent cosmological constant Λef f , effective gravitational constant Gef f and fine structure constant are derived in 5-dimensional Kaluza-Klein model for cosmology. If the internal manifold contracts with time and stabilizes itself at some later time, one possibility gets fine-structure constant equal to (1/137) , G_{ef f} ~ GN and Λ_{ef f} ~ 0 .
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42

Guo, Xiaohu, Kristin Peisker, Kristina Bäckbro, et al. "Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling." Open Biology 2, no. 3 (2012): 120016. http://dx.doi.org/10.1098/rsob.120016.

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Fusidic acid (FA) is a bacteriostatic antibiotic that locks elongation factor G (EF-G) to the ribosome after GTP hydrolysis during elongation and ribosome recycling. The plasmid pUB101-encoded protein FusB causes FA resistance in clinical isolates of Staphylococcus aureus through an interaction with EF-G. Here, we report 1.6 and 2.3 Å crystal structures of FusB. We show that FusB is a two-domain protein lacking homology to known structures, where the N-terminal domain is a four-helix bundle and the C-terminal domain has an alpha/beta fold containing a C4 treble clef zinc finger motif and two l
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43

Suktel, Lokanksha, and Sapan Mohan Saini. "Electron structure and phonon dynamics of LiNbRhAl quaternary Heusler compound." Journal of Physics: Conference Series 2576, no. 1 (2023): 012008. http://dx.doi.org/10.1088/1742-6596/2576/1/012008.

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Abstract Li based quaternary Heusler compounds, having 18 valence electrons show significant applications in different fields i.e., spintronics, thermoelectric and photo voltaic etc. We report the structural stability, electronic property and dynamical stability of LiNbRhAl compound, (Li based QH alloy) via volume optimization and phonon dynamics. Calculations have been performed using Generalized Gradient Approximation based on Density Functional Theory. LiNbRhAl compound crystallizes in LiMgPdSn – type crystal structure having three types of atomic arrangements. We found atomic arrangement o
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44

Koyama, Tomohiro, Yoshinobu Nakatani, Jun’ichi Ieda, and Daichi Chiba. "Electric field control of magnetic domain wall motion via modulation of the Dzyaloshinskii-Moriya interaction." Science Advances 4, no. 12 (2018): eaav0265. http://dx.doi.org/10.1126/sciadv.aav0265.

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We show that the electric field (EF) can control the domain wall (DW) velocity in a Pt/Co/Pd asymmetric structure. With the application of a gate voltage, a substantial change in DW velocity up to 50 m/s is observed, which is much greater than that observed in previous studies. Moreover, modulation of a DW velocity exceeding 100 m/s is demonstrated in this study. An EF-induced change in the interfacial Dzyaloshinskii-Moriya interaction (DMI) up to several percent is found to be the origin of the velocity modulation. The DMI-mediated velocity change shown here is a fundamentally different mecha
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45

Gardill, Bernd R., Ricardo E. Rivera-Acevedo, Ching-Chieh Tung, and Filip Van Petegem. "Crystal structures of Ca2+–calmodulin bound to NaV C-terminal regions suggest role for EF-hand domain in binding and inactivation." Proceedings of the National Academy of Sciences 116, no. 22 (2019): 10763–72. http://dx.doi.org/10.1073/pnas.1818618116.

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Voltage-gated sodium (NaV) and calcium channels (CaV) form targets for calmodulin (CaM), which affects channel inactivation properties. A major interaction site for CaM resides in the C-terminal (CT) region, consisting of an IQ domain downstream of an EF-hand domain. We present a crystal structure of fully Ca2+-occupied CaM, bound to the CT of NaV1.5. The structure shows that the C-terminal lobe binds to a site ∼90° rotated relative to a previous site reported for an apoCaM complex with the NaV1.5 CT and for ternary complexes containing fibroblast growth factor homologous factors (FHF). We sho
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46

Tomlinson, Jennifer H., Arnout P. Kalverda, and Antonio N. Calabrese. "Fusidic acid resistance through changes in the dynamics of the drug target." Proceedings of the National Academy of Sciences 117, no. 41 (2020): 25523–31. http://dx.doi.org/10.1073/pnas.2008577117.

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Antibiotic resistance in clinically important bacteria can be mediated by target protection mechanisms, whereby a protein binds to the drug target and protects it from the inhibitory effects of the antibiotic. The most prevalent source of clinical resistance to the antibiotic fusidic acid (FA) is expression of the FusB family of proteins that bind to the drug target (Elongation factor G [EF-G]) and promote dissociation of EF-G from FA-stalled ribosome complexes. FusB binding causes changes in both the structure and conformational flexibility of EF-G, but which of these changes drives FA resist
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Chataigner, Lucas, Jingxu Guo, Peter T. Erskine, et al. "Binding of Gd3+to the neuronal signalling protein calexcitin identifies an exchangeable Ca2+-binding site." Acta Crystallographica Section F Structural Biology Communications 72, no. 4 (2016): 276–81. http://dx.doi.org/10.1107/s2053230x16003526.

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Calexcitin was first identified in the marine snailHermissenda crassicornisas a neuronal-specific protein that becomes upregulated and phosphorylated in associative learning. Calexcitin possesses four EF-hand motifs, but only the first three (EF-1 to EF-3) are involved in binding metal ions. Past work has indicated that under physiological conditions EF-1 and EF-2 bind Mg2+and Ca2+, while EF-3 is likely to bind only Ca2+. The fourth EF-hand is nonfunctional owing to a lack of key metal-binding residues. The aim of this study was to use a crystallographic approach to determine which of the thre
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Rodnina, Marina V., Frank Peske, Bee-Zen Peng, Riccardo Belardinelli, and Wolfgang Wintermeyer. "Converting GTP hydrolysis into motion: versatile translational elongation factor G." Biological Chemistry 401, no. 1 (2019): 131–42. http://dx.doi.org/10.1515/hsz-2019-0313.

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Abstract Elongation factor G (EF-G) is a translational GTPase that acts at several stages of protein synthesis. Its canonical function is to catalyze tRNA movement during translation elongation, but it also acts at the last step of translation to promote ribosome recycling. Moreover, EF-G has additional functions, such as helping the ribosome to maintain the mRNA reading frame or to slide over non-coding stretches of the mRNA. EF-G has an unconventional GTPase cycle that couples the energy of GTP hydrolysis to movement. EF-G facilitates movement in the GDP-Pi form. To convert the energy of hyd
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49

Opron, Kristopher, and Zachary Burton. "Ribosome Structure, Function, and Early Evolution." International Journal of Molecular Sciences 20, no. 1 (2018): 40. http://dx.doi.org/10.3390/ijms20010040.

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Ribosomes are among the largest and most dynamic molecular motors. The structure and dynamics of translation initiation and elongation are reviewed. Three ribosome motions have been identified for initiation and translocation. A swivel motion between the head/beak and the body of the 30S subunit was observed. A tilting dynamic of the head/beak versus the body of the 30S subunit was detected using simulations. A reversible ratcheting motion was seen between the 30S and the 50S subunits that slide relative to one another. The 30S–50S intersubunit contacts regulate translocation. IF2, EF-Tu, and
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50

Mizokawa, T., A. Ino, T. Yoshida, et al. "ARPES study of LSCO and PBCO: Electronic structure of the stripe phase and the 1/4-filled Cu-O chains." International Journal of Modern Physics B 14, no. 29n31 (2000): 3602–9. http://dx.doi.org/10.1142/s021797920000412x.

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We have studied the electronic structure of the stripe phase in La 2-x Sr x CuO 4 (LSCO) and the Cu-O chains in PrBa 2 Cu 3 O 7 (Pr123) and PrBa 2 Cu 4 O 8 (Pr124) using angle-resolved photoemission spectroscopy (ARPES). In LSCO with x=0.12, the spectral feature near the Fermi level (EF) is almost flat from (π, 0) to (π, π/4), namely, along the stripe direction in LSCO. While the 1/4-filled chain in Pr123 has a band gap because of charge ordering, the metallic chain in Pr124 shows a dispersive feature which reaches EF at ~(π, π/4) and a flat feature near EF which is similar to that observed in
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