Relevant bibliographies by topics / Early onset dementia

Academic literature on the topic 'Early onset dementia'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Early onset dementia"

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Panegyres, Peter K., Simon R. Davles, and Carmela F. Connor. "Early‐onset dementia." Medical Journal of Australia 173, no. 5 (September 2000): 279–80. http://dx.doi.org/10.5694/j.1326-5377.2000.tb125651.x.

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Konijnenberg, Elles, Seyed-Mohammad Fereshtehnejad, Mara ten Kate, Maria Eriksdotter, Philip Scheltens, Peter Johannsen, Gunhild Waldemar, and Pieter Jelle Visser. "Early-Onset Dementia." Alzheimer Disease & Associated Disorders 31, no. 2 (2017): 146–51. http://dx.doi.org/10.1097/wad.0000000000000152.

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Picard, Candice, Florence Pasquier, Olivier Martinaud, Didier Hannequin, and Olivier Godefroy. "Early Onset Dementia." Alzheimer Disease & Associated Disorders 25, no. 3 (2011): 203–5. http://dx.doi.org/10.1097/wad.0b013e3182056be7.

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Bearbi, S., and L. Ali Pacha. "Early onset dementia." Journal of the Neurological Sciences 405 (October 2019): 73. http://dx.doi.org/10.1016/j.jns.2019.10.203.

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Jefferies, Kate, and Niruj Agrawal. "Early-onset dementia." Advances in Psychiatric Treatment 15, no. 5 (September 2009): 380–88. http://dx.doi.org/10.1192/apt.bp.107.004572.

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SummaryDementia is is stereotypically associated with older people. However, in a significant minority it can affect people in their 40s and 50s, or even younger. Currently there is a lack of awareness, even among healthcare professionals, and there is a dearth of appropriate services for such patients. Despite the attention given to this condition by National Institute for Health and Clinical Excellence guidelines, provision of specialist early-onset dementia services in the UK remains patchy. Carers and patients often find themselves being passed ‘from pillar to post’ between psychiatry and neurology, and also between adult, old age and liaison psychiatry. The responsibility for identifying available and appropriate help is often left with carers. This leads to unnecessary delays, causes undue distress to patients and places an added burden on carers.
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Elhusein, Bushra, Omer Bakri Mahgoub, and Abdalla Khairi. "Early-onset dementia: diagnostic challenges." BMJ Case Reports 13, no. 3 (March 2020): e233460. http://dx.doi.org/10.1136/bcr-2019-233460.

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A 56-year-old man was brought to our hospital by his family, seeking medical treatment for the patient’s long-standing progressive word-finding difficulties, forgetfulness, agitation and social withdrawal. After multiple previous physician consultations, the patient was mistakenly diagnosed with epilepsy and prescribed multiple anticonvulsants, to which his above mentioned symptoms were unresponsive. His condition progressed over the next 10 years, resulting in severe cognitive impairments and a complete dysfunctionality. An electroencephalogram (EEG) assessment revealed persistent spike and wave activity in the left temporal lobe. Brain MRI revealed multiple small bright T2 and fluid attenuated inversion recovery (FLAIR) foci within the white matter of both cerebral hemispheres surrounding the ventricular system, as well as some widening of extra-axial cerebrospinal fluid spaces. The patient was finally diagnosed with early-onset dementia and temporal lobe epileptiform abnormalities. This case emphasises the need for diagnostic consideration of dementia in cognitively impaired patients, even when they are not of an advanced age.
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MIYOSHI, Koho. "What is ‘early onset dementia’?" Psychogeriatrics 9, no. 2 (June 2009): 67–72. http://dx.doi.org/10.1111/j.1479-8301.2009.00274.x.

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McMurtray, Aaron, David G. Clark, Dianne Christine, and Mario F. Mendez. "Early-Onset Dementia: Frequency and Causes Compared to Late-Onset Dementia." Dementia and Geriatric Cognitive Disorders 21, no. 2 (2006): 59–64. http://dx.doi.org/10.1159/000089546.

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Tjong, Elysia, William McHugh, and Yen-Yi Peng. "Reversible dementia: subclinical seizure in early-onset dementia." Clinical Case Reports 5, no. 3 (February 6, 2017): 321–27. http://dx.doi.org/10.1002/ccr3.843.

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Coolidge, Frederick L., Bruce M. Peters, Ruby E. Brown, Terri L. Harsch, and Tom G. Crookes. "Validation of a WAIS Algorithm for the Early Onset of Dementia." Psychological Reports 57, no. 3_suppl (December 1985): 1299–302. http://dx.doi.org/10.2466/pr0.1985.57.3f.1299.

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A WAIS algorithm was developed to distinguish between the onset of dementia and depression. Seven WAIS subtests were given to 148 patients whose diagnosis was doubtful. They were classified after a minimum of 1 yr. later as dementia ( n = 50) or as depression ( n = 98). The algorithm, developed from a discriminant function analysis, indicates dementia if the Vocabulary scaled score is greater than or equal to double the Block Design scaled score. The algorithm predicted 74% of the dementias and 74.5% of the depressions, for an over-all prediction rate of 74.3% (110 of 148 cases). These results indicate that the algorithm, if cross-validated, may be a useful adjunctive diagnostic tool in the differential diagnosis of early dementia from depression.
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Dissertations / Theses on the topic "Early onset dementia"

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Zeher, Jamie. "Young-Onset Dementia: The Child's Experience with Coping." Honors in the Major Thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/936.

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Young onset dementia (YOD) affects not only the person diagnosed, but the family unit as a whole. It is estimated that as many as 500,000 people in the United States have YOD and around 250,000 children are involved in caring for these people. A child of a parent with YOD can begin to experience negative effects when the child begins to take part in caregiving for the person with young onset dementia (PWYOD). Feelings of stress, anger, fear of the future, depression, social isolation, and increasing responsibility of caring for the PWYOD can be felt by children as caregivers. Research shows that children of people with YOD have reported an extreme lack of support and decreased communication within the family. The purpose of this thesis was to examine current interventions designed to improve coping for children of parents with YOD. A review of literature using CINAHL, Medline, and PsychINFO was conducted to gather peer-reviewed articles and journals relating to interventions to help children of parents with YOD cope. However, no studies have discussed interventions specifically for the child. Therefore, information was pulled from 5 studies regarding what children of people with YOD feel has helped them, in their respective experiences, to deal with the stresses of a parent with YOD. Research suggests that individualized care should be provided for these children based on: age, developmental stage, and experience. Children have reported that they cope by spending time away from the home, participating in extracurricular activities, and spending time with friends. Clear communication by all members of the family is also reported to be vital in easing the stresses of caring for a parent with YOD. While children have developed these coping mechanisms, interventions need to be formally designed and their effect on improving coping examined. Analyzing the experiences of the children with parents with YOD is necessary for clinicians to gain insight into what interventions worked for this population, and what interventions need to be created for further and more individualized support.
B.S.N.
Bachelors
Nursing
Nursing
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Rudge, John. "Early onset frontotermporal dementia and alzheimers disease : diagnosis, treatment and care." Murdoch University, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20090424.143035.

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This research investigated two groups of patients diagnosed with dementia before the age of sixty-five. The patients were diagnosed with Alzheimer’s Disease (AD, n = 25) and Frontotemporal Dementia (FTD, n = 37). Patients were assessed for approximately 3 years. The study found that FTD is a valid and useful diagnostic category, and can be reliably differentiated from AD. A combination of behavioural, neurological, and neuropsychological assessments were found to be complementary in the early and accurate diagnosis of early-onset dementia, and the differential diagnosis of FTD from AD. FTD patients were found to have relatively preserved visuo-spatial abilities compared to the AD patients. Problems associated with administering neuropsychological tests to early-onset dementia patients were highlighted. FTD patients were found to deteriorate more rapidly than AD patients, and to have significantly increased behavioural disturbances throughout the course of the illness in comparison with the AD patients. Practical guidelines to assist with care and management of early-onset dementia patients were presented. A strengths-based model of care was outlined. Individualised assessments and care plans were recommended for the development and provision of humane services to early-onset dementia patients. Issues surrounding providing palliative care were discussed.
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Beanblossom, Kathryn M. "EXPLORING THE EXPERIENCES AND PERCEPTIONS OF PERSONS DIAGNOSED WITH EARLY ONSET DEMENTIA AND THEIR PRIMARY CAREGIVERS." Miami University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=miami1366835742.

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Candey, Louise. "Women's understandings of their relationship with their husband in the early stages of his gradual onset dementia." Thesis, University of East Anglia, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246967.

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Objectives: This study attempted to conceptualize women's understandings of the changes in their marital relationship in the first six months following a husband's diagnosis of gradual onset dementia, the nature and mechanism of transition to the role of caregiver, and the construal of the marriage in contrast to other care oriented relationships. Method: Six wives whose husbands had been diagnosed with gradual onset dementia in the previous six months participated. The qualitative techniques of grounded theory and data displays were applied to data derived from qualitative semi-structured interviews. This data was triangulated with rated repertory grids of care relationships, analyzed using a variant of INGRID. Results: The qualitative analysis yielded six significant categories pertaining to the research questions, organized temporally. A pre-existing relationship was punctuated unexpectedly by changes in a husband (catalysts) to which a wife reactively responded (adjustments of power and intrapersonal processes, and emotional consequences). This dynamic and continuous process driven by a husband's deterioration was termed 'role making'. A tripartite typology of pre-existing informal marital contracts emerged from the data underpinned by dimensions of 'power' and 'merging of identity'. This had utility in predicting the emotional consequences a wife was likely to experience, and the catalysts proving to be problematic, but not endorsement of a 'wife' or 'caregiver' role. The repertory grid analysis revealed that none of the wives replicated wholesale a 'parental' mothering model in caring for their husbands, but integrated aspects of different prior caring experiences in a flexible way, in accordance with situational demands. Conclusion: Wives' adjustments in the relationship, and the emotional impact of caring for a husband in the early stages of dementia are significant, and largely una~knowledged. There is also a need for the recognition of the importance of the marital relationship, beyond a predetermined definition of 'quality'.
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Ashworth, Rosalie Marie. "Experiences of early and late-onset Alzheimer's disease : perceptions of stigma and future outlook." Thesis, University of Stirling, 2015. http://hdl.handle.net/1893/24380.

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Diagnosis of Alzheimer’s disease is encouraged as a first step towards people planning for their future with the condition. Despite the proposed benefits of diagnosis, it is also widely recognised that Alzheimer’s disease can expose people to stigma. Therefore, this thesis explores the relationship between stigma and future outlook, from the perspective of people affected by early and late-onset Alzheimer’s disease. In order to recognise the physicality of the condition and how psychological and social factors influence experiences, a biopsychosocial perspective is employed throughout. People with Alzheimer’s disease (n=15 people with late-onset, 7 people with early-onset) and their supporters (n=22) completed questionnaires about perceived stigma. This was followed by 14 interviews with a subsample of participants, which explored stigma and future outlook in more depth. Perceived stigma reporting across participants was low in the questionnaires; whereas interviews revealed higher levels of stigma with people discussing mixed, unpredictable reactions from a range of sources. Participants expressed awareness of the unpredictable nature of their futures with the condition. The subsequent lack of control was managed through focusing on ‘one day at a time’ and avoiding looking too far ahead. Across reflections on stigma and future outlook there was a deliberate focus on positive experiences for people affected by early and late-onset Alzheimer’s disease. The similar management of experiences across participants minimised possible age-based differences. These findings are supported by socioemotional selectivity theory, which suggests people are motivated to maintain positive emotional states when facing ‘time-limiting’ conditions irrespective of age. The research suggests people’s experiences of stigma and future outlook interact, with stigma-driven assumptions about the future affecting how people manage their daily lives. The avoidance of looking ahead suggests that policy which encourages future planning should consider its utility and explore ways of helping people to manage both exposure to stigma, and planning for the future, whilst focusing on daily living.
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Wawrziczny, Emilie. "Analyse des besoins et accompagnement des conjoints de personnes jeunes avec une maladie d'Alzheimer." Thesis, Lille 3, 2016. http://www.theses.fr/2016LIL30030/document.

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La thèse a pour objectifs d'identifier les besoins et les difficultés des conjoints aidants de personnesprésentant une maladie d'Alzheimer. Elle vise également à mettre en évidence les points communs etles spécificités de la situation d’aide en fonction de l’âge d’apparition de la maladie. L’axe 1 porte sur l’analyse du vécu de couples dont l'un des partenaires présente une démence précoce. Les résultats mettent en évidence une évolution dans le rapport au savoir des aidants et des personnes malades. Ils passent d'un besoin de comprendre les changements occasionnés par l’arrivée de la maladie à une mise à distance après l'annonce du diagnostic. De plus, avec l'avancée des troubles, les aidants éprouvent des difficultés à ajuster leur niveau d’aide, ce qui est source de conflits entre les deux partenaires. Les deux études de l'axe 2 ont pour objectif d’établir une comparaison entre les aidants de personnes malades jeunes et de personnes malades âgées à la fois sur leurs besoins et sur leurs modes d’ajustement. La majorité des besoins et des stratégies est commune à tous les aidants. Néanmoins, les aidants de personnes malades jeunes expriment plus de besoins en termes de maintien de contact, d'adaptation des structures de soins et d'accompagnement dans les démarches administratives. Les aidants de personnes malades âgées utilisent plus l'humour, l'aménagement et la mise à distance de l'entourage comme stratégies d'ajustement. L’axe 3 vise à investiguer l'influence des caractéristiques de la situation d'aide sur la détresse du conjoint aidant à l’aide d’une modélisation structurale. Les paramètres de ce modèle général ont été comparés en fonction de l'âge de début de la maladie et du genre de l'aidant. Cette étude met en évidence 4 facteurs influençant le sentiment de détresse des conjoints aidants : le sentiment d'être préparé, la qualité du support familial, l’évaluation de sa santé et la qualité d’ajustement du couple. Ce dernier facteur est plus important pour les conjoints aidants de personnes malades jeunes. L’analyse de ces résultats permet de spécifier le contenu de programmes d’accompagnement en faveur de modules communs à tous les aidants et de modules spécifiques en fonction de l'âge d'apparition de la maladie
This thesis aims to identify needs and difficulties of the spouse caregivers of persons with dementia. We also investigate similarities and specificities related to the caregiving situation regarding the age atonset of the disease.The first axis examines the experience of couples in which one member received a diagnosis of earlyon setdementia. The results show an evolution in the relation to knowledge of the caregivers and the persons with dementia. They oscillate between the need to understand the changes caused by the disease and a distancing after the diagnosis. Moreover, with the progression of the disease, the caregivers are not able to adapt their level of assistance, which increases tensions between the two partners. The two studies of the second axis aim to compare needs and coping strategies of spouse caregivers of persons with early and late onset dementia. The majority of needs and strategies are the same for all spouse caregivers. However, the spouse caregivers of persons with early-onset dementia express the greatest number of needs related to maintaining contacts, more need of adapted care structures and more need to be assisted in administrative procedures. The spouse caregivers of persons with late-onset dementia use more humor, re-arranging, and getting away from the entourage. The third axis investigates the influence of the characteristics of the caregiving context on spousal caregiver distress with a structural modelisation. The sittings of this general model were compared regarding the age at onset of the disease and the gender of caregiver. This study demonstrated that 4 factors contribute to spousal caregiver distress: preparedness, family support, self-rated health and the quality of the couple relationship. Dyadic determinants were more important for caregivers of PEOD. The analysis of these results permits to specify the content of support for a common core and specific modules depending on the age at onset of the disease
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Webber, Graham Ross, and graham webber@bigpond com. "Reiki: Practitioners� Perceptions of the Effectiveness of a Complementary Therapy in the Treatment Regime of People with Dementia." Flinders University. Department of Disabilities Studies, School of Medicine, 2006. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20061009.093745.

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International and national research has shown that the use of complementary therapies (often referred to in the scientific literature as either alternative therapies or unconventional therapies) is widespread. However, there is little in the scientific literature about the use of complementary therapies in the treatment regime of people with dementia. Specifically, there have been no published results of investigations into the use of Reiki, a holistic complementary therapy, in the treatment regime of people with dementia. Before proceeding with an in-depth examination into the use of Reiki in the care of people with dementia, a questionnaire containing both closed and open-ended questions was distributed to 162 South Australian High Care Residential Facilities (formerly called Nursing Homes) in 2002. The return rate was 58.0% (n=94) of which 50.0% of the mail out (n=81) was available for analysis. Findings from the questionnaires suggested that a wide range of complementary therapies including aromatherapy, massage, music, behaviour therapy, healing touch, Reiki and Therapeutic Touch (Krieger/Kunz method) were used regularly within South Australian High Care Residential Facilities. Complementary therapies were reportedly used to calm residents, improve behaviour management, enhance the quality of life of residents, promote 1:1 interaction, stimulate the senses, and reduce the need for medication. Due to 15 facilities reporting the use of Reiki, a series of semi-structured interviews with Reiki practitioners caring for people with dementia was conducted in 2004/2005. Interview participants (n=10) included a representative range of people providing care for people with dementia in eight Nursing Homes in Adelaide, South Australia. Data reduction methods included a quasi-statistical counting of key words and repeated re-readings of the transcripts to discover the essences, abstract the meanings and arrange them into themes and sub-themes. The results of the interviews suggested that Reiki is an easy to learn and easy to use holistic complementary therapy which has the potential to enhance the quality of life of the persons with dementia, their family members, and their carers. The interview participants reported improved physical, psychological, mental and emotional well-being as well as enhanced relationships and a reduction in negative behaviours following the use of Reiki. The receipt of the first Jack Loader Scholarship from the Rosemary Foundation for Memory Support Inc. in early 2005 enabled the researcher to transfer to full-time studies from April 2005. Key Words: aged care; alternative therapies; complementary therapies; dementia; early onset dementia; one to one interaction; quality of life; Reiki; therapeutic touch; unconventional therapies.
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Larsson, Lena. "Har han det bra så har jag det bra : ett aktionsforskningsprojekt där ett närståendestöd planerades i samarbete med närstående till yngre personer med demenssjukdom." Thesis, Kristianstad University College, School of Health and Society, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-4800.

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Om närstående ska orka leva tillsammans med en yngre demenssjuk partner behöver de erbjudas stöd som är utformat utifrån deras situation och behov. Syftet var att i samarbete med närstående till personer vars demenssjukdom debuterat före 65 års ålder planera ett närståendestöd. Metoden som användes var Participatory Action Research (PAR), en interaktiv forskningsmetod som innefattar reflektion, analys och handling. Fokusgruppssamtal genomfördes med två fokusgrupper vid vardera tre tillfällen. Samtliga deltagare var make eller maka som levde tillsammans med en yngre demenssjuk partner. Studien visade att närstående genomgår en process som har stora likheter med och följer den transitionsprocess som personen med demenssjukdom går igenom. Initialt upplevde närstående oro, ovisshet,ensamhet och osäkerhet och man upplevde brist på stöd. För att lindra dessa upplevelser krävs indirekt stöd riktat mot den sjuke och direkt stöd riktat mot den närstående. Tidigt i sjukdomsförloppet behövs individuellt anpassat stöd som bör förändras i takt med att sjukdomsprocessen fortskrider. Att ha tillgång till en person som kan fungera som lots mellan de olika övergångar närstående går igenom var betydelsefullt.


Living together with a younger spouse who is suffering from dementia requires that relatives are offered support. The aim of this Participatory Action Research (PAR) project was to, in collaboration with relatives, plan support for relatives to persons with dementia below 65 years of age. PAR is an interactive research method based on reflection, analysis and action. Two groups of relatives participated in focus groups at three occasions and data were content analysed. Relatives were wives or husbands to a younger person with dementia. Findings showed that relatives pass through a similar transition process as the person. It is important to offer individualized support initially, support that needs to be changed as the disease proceeds. Furthermore, the study showed that if relatives shall manage their own anxiety, uncertainty, and feelings of loneliness, emotional support is necessary. However, it is impossible to just offer direct support to the relatives without considering the sick persons’ needs. Finally, a personal guide that could follow the couple trough the entire process would be of importance.

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Ayaki, Takashi. "Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant." Kyoto University, 2015. http://hdl.handle.net/2433/200437.

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Oyebode, Jan R. "Living with young-onset dementia." 2014. http://hdl.handle.net/10454/7100.

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Books on the topic "Early onset dementia"

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Cox, Sylvia M. Guide to early onset dementia. Stirling: Dementia Services Development Centre, 1994.

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Cox, Sylvia M. A guide to early onset dementia. Stirling: University of Stirling, Dementia Services Development Centre, 1994.

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Hodges, John. Early-Onset Dementia: A Multidisciplinary Approach. Oxford University Press, USA, 2001.

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Early-onset dementia: A multidisciplinary approach. Oxford: Oxford University Press, 2001.

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1955-, Williams Tim, and Leeds Health Authority, eds. From pillar to post: Early onset dementia in Leeds : prevalence, experience and service needs. Leeds: Leeds Health Authority, 1999.

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Willie, Barker, Barrett Ken, Muth Zena, Williams Richard, and NHS Health Advisory Service, eds. Mental health services: Heading for better care : commissioning and providing mental health services for people with Huntington's disease, acquired brain injury and early onset dementia. London: H.M.S.O., 1997.

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Allen, Shelley J., and David Dawbarn. Pathophysiology of Alzheimer’s disease. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199569854.003.0004.

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• Alzheimer’s disease (AD) is a progressive dementia with loss of neurons and the presence of two main microscopic neuropathological hallmarks: extracellular amyloid plaques and intracellular neurofibrillary tangles• Early onset AD, the rare familial form, is the result of a mutation in one of three genes: ...
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Hanney, Maria Luisa. Older people with learning disabilities. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199644957.003.0050.

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Elderly people with Learning Disabilities are a heterogeneous clinically complex population with unique medical and social challenges. Little is known of the epidemiology of mental ill health in this group. Emerging evidence indicates that they suffer higher rates of mental illness than the general population and than their younger peer group. Point prevalence of mental ill health in elderly people with Learning Disabilities has been reported about 69% compared with 48% in the younger peer group. This higher rate of psychiatric diagnosis in the older group is mainly due to a higher rate of dementia of about 21 %. People with Down syndrome appear to have lower rates of mental ill health apart from depression and early onset dementia of Alzheimer’s type. People with Learning Disability due to other causes are also at higher risk of developing dementia at an earlier age than the general population
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Verrips, Aad. Cerebrotendinous Xanthomatosis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0040.

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Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disease due to a defect in bile acid metabolism. Worldwide, more than 300 patients have been described. Mutations in the CYP27A1 gene result in sterol 27-hydroxylase deficiency leading to the accumulation of cholestanol in multiple body tissues. Premature cataracts, chronic diarrhea, tendon xanthomas, and neurological deterioration are the predominant clinical features. There are several disease stages, from being nearly asymptomatic in the early childhood years to severe disability in later stages of life. Adult CTX patients are often misdiagnosed initially, especially when tendon xanthomasa are absent. CTX should be considered in all patients with premature cataracts and in patients with neurological features such as spasticity, early-onset dementia, ataxia, or Parkinsonism.
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Chneiweiss, Hervé. Anticipating a therapeutically elusive neurodegenerative condition: Ethical considerations for the preclinical detection of Alzheimer’s disease. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198786832.003.0016.

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Among neurodegenerative disorders, Alzheimer’s disease has held a special position during the last 40 years. It represents a huge burden of disease with more than 40 million people affected worldwide. The economic effect it has on society is enormous, and the specific challenges of dementia are tremendous. Now that science has demonstrated that the disease starts two or three decades before any symptoms occur, possibilities exist for diagnosis or testing increasingly early through the capabilities of predictive medicine. The related ethical debate is on the multiple meanings and the impact of preclinical diagnosis of Alzheimer’s disease before the onset of symptoms. To guide this discussion, this chapter draws upon lessons from other fields of medicine and the identification of high-risk individuals bearing pathogenic genetic mutations that predispose them to the disease. It concludes with thoughts on value and choice in the complex, fine balance between anticipating, knowing, and doing.
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Book chapters on the topic "Early onset dementia"

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St George-Hyslop, Peter H. "Genetics of early-onset Alzheimer disease." In Neuroscientific Basis of Dementia, 153–65. Basel: Birkhäuser Basel, 2001. http://dx.doi.org/10.1007/978-3-0348-8225-5_18.

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Wasco, Wilma, and Rudolph E. Tanzi. "Etiological Clues from Gene Defects Causing Early Onset Familial Alzheimer’s Disease." In Molecular Mechanisms of Dementia, 1–19. Totowa, NJ: Humana Press, 1997. http://dx.doi.org/10.1007/978-1-59259-471-9_1.

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Van Broeckhoven, C., H. Backhovens, W. Van Hul, G. Van Camp, P. Stinissen, A. Wehnert, P. Raeymaekers, et al. "Genetic Linkage Analysis in Early-Onset Familial Alzheimer’s Dementia." In Neuropsychopharmacology, 86–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74034-3_9.

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"Early Onset Dementia." In Encyclopedia of Clinical Neuropsychology, 921. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-0-387-79948-3_4235.

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Fadil, Halim, Aimee Borazanci, Elhachmia Ait Ben Haddou, Mohamed Yahyaoui, Elena Korniychuk, Stephen L. Jaffe, and Alireza Minagar. "Chapter 13 Early Onset Dementia." In International Review of Neurobiology, 245–62. Elsevier, 2009. http://dx.doi.org/10.1016/s0074-7742(09)00413-9.

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Xefteris, Stefanos, Evdokimos Konstantinidis, Antonis S. Billis, Panagiotis E. Antoniou, Charis Styliadis, Evangelos Paraskevopoulos, Panagiotis Emmanouil Kartsidis, Christos A. Frantzidιs, and Panagiotis D. Bamidis. "Early Detection of Dementia." In Data Analytics in Medicine, 1963–88. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1204-3.ch098.

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Early detection and prediction of dementia through unobtrusive techniques or obtrusive tests is still in exploratory status and despite the increase of interest in recent years, many challenges remain open in designing methodologies that can accurately predict its onset. This chapter addresses the problem of the early detection of dementia from two points of view: Detection based on unobtrusive paradigms both in lab and home environments (behavioral monitoring, serious games, home based assisted living applications in telemedicine) and detection based on neuroimaging approaches. The chapter also provides information on setting up ecologically valid home labs for dementia related experiments. Consequently, the aim of this chapter is to provide an overview of a complete methodology of how researchers can possibly detect or predict the onset of dementia through the current state-of-the-art, underline open challenges and illustrate future work in the field.
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Bocchetta, Martina, and Jonathan D. Rohrer. "Frontotemporal dementia." In Oxford Textbook of Old Age Psychiatry, 513–26. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198807292.003.0033.

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The term frontotemporal dementia (FTD) describes a heterogeneous group of neurodegenerative disorders with multiple genetic and pathological causes. However, there is sufficient overlap both clinically, in terms of behavioural and/or language difficulties, and anatomically, with neuronal loss occurring in the frontal and temporal lobes, that the conditions are commonly considered together as one group. Overall, the FTD disorders represent a common cause of early-onset dementia, approximately equal in frequency to Alzheimer’s disease in people under the age of 65. The only known risk factors are genetic, and about a third of cases are due to an autosomal dominant mutation. No curative treatment is currently available and symptomatic and supportive care is the mainstay of management. This chapter discusses the concept of FTD, describing its clinical presentation, genetics, neuropathology, neuroimaging, fluid biomarkers, and management.
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Buraye, Jacqueline Arabia, and María Cristina Quijano Martínez. "Colombia." In Dementia Care: International Perspectives, 337–44. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198796046.003.0045.

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Dementia is among those diseases with an increased incidence in older people, which, according to population projections, will have an increasing impact in the coming years. Currently, it is estimated that worldwide, 7% of people aged above 65 years, and 20–30% of those aged above 80 years, present with cognitive impairment. Colombia is not spared this reality. This chapter reviews the prevalence of the disease, the current situation in the country, and the challenges, as well as proposed management alternatives for families, caregivers, and the community and clinical trial research in families at genetic risk of developing hereditary early-onset Alzheimer’s disease.
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Castle, David J., Ana Lusicic, and Melissa Petrakis. "Early intervention in psychiatry." In Oxford Textbook of Public Mental Health, edited by Dinesh Bhugra, Kamaldeep Bhui, Samuel Y. S. Wong, and Stephen E. Gilman, 399–410. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198792994.003.0043.

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Early intervention in psychiatry has enormous appeal in the sense that it can reduce distress and disability and promote better long-term outcomes. However, extant research is patchy in terms of defining precisely what ‘early intervention’ should entail, as well as determining the elements of such interventions that might be helpful and not harmful. This chapter provides a brief overview of selected disorders, encompassing examples of disorders that have an onset in childhood (autism), teenage years/early adulthood (bipolar disorder), and in later life (dementia). The chapter then focuses on schizophrenia, as schizophrenia is a disorder ubiquitous across the globe in terms of prevalence, which carries substantial disability, and for which there has been a worldwide investment in early intervention.
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Blass, David M. "Frontotemporal Dementia." In Psychiatric Aspects of Neurologic Diseases. Oxford University Press, 2008. http://dx.doi.org/10.1093/oso/9780195309430.003.0017.

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Frontotemporal dementia (FTD) is a family of neurodegenerative diseases and syndromes that most commonly involve the frontal and temporal lobes, producing dramatic alterations of personality, behavior, language, and other cognitive abilities (McKhann et al., 2001). Age of onset tends to be younger than in Alzheimer’s disease (AD), with most patients becoming symptomatic in the sixth decade of life. Although population-based epidemiologic studies of FTD have found a prevalence of approximately 5–10 per 100,000 in patients 50 years of age and older, autopsy-based case series have found that approximately 5% to15% of people with dementia have FTD, a discrepancy suggesting that many cases go undiagnosed during life (Rosso et al., 2003). Recent advances in clinicopathologic correlation have revealed that a number of neurologic conditions previously conceived of as independent disease entities such as progressive supranuclear palsy (PSP), corticobasilar degeneration (CBD), and hippocampal sclerosis dementia are in many cases better classified in the FTD family (McKhann et al., 2001; Blass et al., 2004). Many patients with FTD develop other neurologic syndromes as well, including parkinsonism and amyotrophic lateral sclerosis (ALS). FTD is actually a group of clinical syndromes with overlapping neuropathologies. The clinical expression of the disease relates primarily to the anatomic location of disease involvement rather than the neuropathologic subtype; there are many such subtypes. Clinical variants are most distinct early in the disease course, when the degree of anatomic involvement may be limited to discrete regions. As the disease spreads through the brain, many patients have symptoms that become complex and take on char acteristics of other variants. The first clinical FTD variant is one in which behavioral abnormalities and personality changes dominate the clinical presentation. This syndrome is usually associated with disease involvement of the frontal and anterior temporal lobes. In addition, there are two language presentations: primary progressive aphasia and semantic dementia (McKhann et al., 2001). The neurologic syndromes of PSP, CBD, and ALS with dementia are familiar to the neurologist because of their neurologic symptoms; it is noteworthy that patients with any of the previously mentioned syndromes routinely develop the psychiatric symptoms reviewed below.
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Conference papers on the topic "Early onset dementia"

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Seng Ting, Simon Kang, Celeste Chen, Huihua Li, Shahul Hameed, Adeline NG, Eng-King Tan, Kok Pin Ng, and Nagaendran Kandiah. "20 Clinical characteristics of pathological confirmed early onset dementia with lewy bodies." In The British Neuropsychiatry Association – Annual Meeting. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/jnnp-2019-bnpa.20.

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Zeng, Zhiwei, Hongchao Jiang, Yanci Zhang, Zhiqi Shen, Jun Ji, Martin J. Mckeown, Jing Jih Chin, Cyril Leung, and Chunyan Miao. "A Gamified Assessment Platform for Predicting the Risk of Dementia +Parkinson’s disease (DPD) Co-Morbidity." In Twenty-Ninth International Joint Conference on Artificial Intelligence and Seventeenth Pacific Rim International Conference on Artificial Intelligence {IJCAI-PRICAI-20}. California: International Joint Conferences on Artificial Intelligence Organization, 2020. http://dx.doi.org/10.24963/ijcai.2020/775.

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Population aging is becoming an increasingly important issue around the world. As people live longer, they also tend to suffer from more challenging medical conditions. Currently, there is a lack of a holistic technology-powered solution for providing quality care at affordable cost to patients suffering from co-morbidity. In this paper, we demonstrate a novel AI-powered solution to provide early detection of the onset of Dementia + Parkinson's disease (DPD) co-morbidity, a condition which severely limits a senior's ability to live actively and independently. We investigate useful in-game behaviour markers which can support machine learning-based predictive analytics on seniors' risk of developing DPD co-morbidity.
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Daianu, Madelaine, Neda Jahanshad, Mario F. Mendez, George Bartzokis, Elvira E. Jimenez, and Paul M. Thompson. "Communication of brain network core connections altered in behavioral variant frontotemporal dementia but possibly preserved in early-onset Alzheimer's disease." In SPIE Medical Imaging, edited by Sébastien Ourselin and Martin A. Styner. SPIE, 2015. http://dx.doi.org/10.1117/12.2082352.

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