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Dissertations / Theses on the topic 'E2ES'

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1

Sandy, April R. "The role of E2Fs in mammary gland development." Connect to resource, 2006. http://hdl.handle.net/1811/6624.

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Thesis (Honors)--Ohio State University, 2006.<br>Title from first page of PDF file. Document formatted into pages: contains 17 p.; also includes graphics. Includes bibliographical references (p. 16-17). Available online via Ohio State University's Knowledge Bank.
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Chen, Hui-Zi. "Mammalian Atypical E2Fs Link Endocycle Control to Cancer." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1316540844.

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Rakijas, Jessica B. "E2Fs and Transcription: New Members Help Answer Old Questions." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492780032915208.

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Sun, Daokun. "E2F Proteins Regulate Cell Proliferation and Differentiation in Development." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1562695239955401.

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5

Docquier, Aurélie. "Rôle du corégulateur transcriptionnel RIP140 dans la signalisation par les facteurs E2Fs." Thesis, Montpellier 1, 2010. http://www.theses.fr/2010MON1T018.

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Le contrôle du cycle cellulaire, processus fondamental pour la prolifération cellulaire, est souvent altéré au cours de la tumorigenèse. Les facteurs de transcription E2Fs sont des régulateurs majeurs de l'expression de gènes impliqués dans le cycle cellulaire, la réplication de l'ADN, la mort cellulaire programmée ou encore la différenciation cellulaire. La famille des facteurs E2Fs contient des membres qui agissent comme activateurs ou répresseurs de la transcription et dont l'activité est régulée par un grand nombre de corégulateurs transcriptionnels, incluant notamment les protéines à poch
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Yampolskiy, Mark. "Maßnahmen zur Sicherung von E2E-QoS bei Verketteten Diensten." Diss., kostenfrei, 2009. http://edoc.ub.uni-muenchen.de/10971/.

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7

Gemae, Raghda. "The Role of Activating E2Fs in Neural Stem Cell Maintenance from Development to Adulthood." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35587.

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The recent discovery of adult neural precursor cells (NPCs) in the dentate gyrus and the subventricular zone of the lateral ventricles of most mammals holds much hope for the potential regeneration of damaged brain tissue. However, their use has been limited by their low numbers and relatively quiescent state, particularly in the aging brain. Previous studies from our laboratory have demonstrated a crucial role for the Rb/E2F pathway in the regulation and proliferation of NPCs, and the direct mechanistic involvement of E2F3 in regulating the pluripotency factor, Sox2. More recently, our invest
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Yakubovich, Edward. "The Role of Activator E2Fs in Neural Stem Cell Activation and Exit from Quiescence." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39437.

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Regenerative medicine offers tremendous potential for the treatment of irreversible damage to the brain. Activation of quiescent adult neural stem cells by clinical means to regenerate tissue can improve pathological outcomes of patients afflicted by brain trauma. Control of the cell- cycle is important in activating quiescent neural stem cells for the purpose of enhancing adult neurogenesis. Here, we uncover the role of cell-cycle regulatory transcription factors E2F1 and E2F3 in adult neural stem cell activation and characterize it. We hypothesize that the Retinoblastoma-E2F pathway is cruci
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Dugal-Tessier, Delphie. "The Role of Atypical E2fs in the Maintenance and Development of the Ependymal Cell Barrier." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34454.

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The discovery of neural stem cells within the adult CNS has indicated an enormous potential in facilitating neuronal regeneration after injury. Studies from our laboratory have suggested that manipulation of the Rb/E2f pathway can directly impact embryonic and adult neurogenesis, thereby having tremendous potential for neuronal regeneration therapies. Recently, two new members of the Rb/E2f pathway have been discovered, the atypical E2fs: E2f7 and E2f8. Initial studies have suggested that atypical E2fs regulate diverse processes such as cell proliferation, DNA-stress response, apoptosis, howev
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Stevenson, Amadeus. "Interactions of nanoparticles with cells for nanomedical applications." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:ecde4b01-e2ec-42f4-9353-72071b845775.

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Nanotechnology is a rapidly growing field focused on the manipulation and control of materials with dimensions under 100 nm. The novel electronic, optical and mechanical properties observed at the nanoscale have resulted in a number of applications in catalysis, light emitting devices, solar power, self-cleaning surfaces and medicine. Medical applications of nanotechnology (“nanomedicine”) are particularly promising for rapid clinical diagnosis and targeted treatments. Understanding the interactions of nanoparticles with living matter is of fundamental importance for all application areas: man
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Rodrigo, Brenni Monica C. "E2s act sequentially in the assembly of ubiquitin chains by the anaphase-promoting complex." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3378504.

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12

Antwi-Ansorge, Nana Akua. "Ethnic mobilisation and the Liberian civil war (1989-2003)." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:9d7a54b2-e2e9-4f72-aad4-2301e9cf2def.

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This thesis examines the relationship between ethnicity and violent group mobilisation in Liberia’s civil war (1989-2003). It focuses on Gio, Mano and Mandingo mobilisation to investigate how and why internal dynamics about moral norms and expectations motivated leadership calls for violence and ethnic support. Much of the existing literature interprets popular involvement in violent group mobilisation on the Upper Guinea Coast as a youth rebellion against gerontocracy. I argue that such an approach is incomplete in the Liberian case, and does not account for questions of ethnic mobilisation a
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13

Thomson, Oliver. "Clinical decision making and therapeutic approaches of experienced osteopaths." Thesis, University of Brighton, 2013. https://research.brighton.ac.uk/en/studentTheses/c1120835-e2e7-46c7-82c2-364a1facf1d2.

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Clinical decision-making refers to the social, cognitive and interactive processes by which practitioners make choices in relation to the examination, diagnosis, treatment and management of patients. It is fundamental for effective and efficient clinical practice and is central to professional autonomy and accountability. As the profession continues to grow, osteopathy is playing an increasingly important role in musculoskeletal healthcare. While research has identified the clinical decision-making approaches taken by a range of healthcare professions, there is limited understanding of how ost
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Ralambotiana, Miora. "Key management with a trusted third party using LoRaWAN protocol : A study case for E2E security." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-230671.

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Nowadays, Internet of Things (IoT) applications are gaining more importance in people’s everyday life. Depending of their usage (for long or short distance communications, using low or high power devices, etc.), several standards exist. In this study, the focus is on Low Power Wide Area Networks (LPWAN) and particularly a protocol which is raising in popularity for long-range low-power communications in IoT: LoRaWAN. LoRaWAN is still at an early stage and has been mainly used in use cases where the network server was managing the keys ensuring confidentiality and integrity of the data. Gemal
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Varejão, Junior Gleudson Pinheiro. "Proposta de um modelo para verificabilidade E2E no sistema eletrônico de votação brasileiro utilizando mecanismos de criptografia visual." Universidade Federal de Pernambuco, 2014. https://repositorio.ufpe.br/handle/123456789/11487.

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Submitted by Luiz Felipe Barbosa (luiz.fbabreu2@ufpe.br) on 2015-03-09T14:26:19Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) DISSERTAÇÃO Gleidson Pinheiro Varejão Júnior.pdf: 5786318 bytes, checksum: db03ae4c22592a31990484cac439eb0d (MD5)<br>Made available in DSpace on 2015-03-09T14:26:20Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) DISSERTAÇÃO Gleidson Pinheiro Varejão Júnior.pdf: 5786318 bytes, checksum: db03ae4c22592a31990484cac439eb0d (MD5) Previous issue date: 2014-08-21<br>A his
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Wakim, Mike. "Employing Android Security Features for Enhanced Security and Privacy Preservation." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36353.

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In this thesis, we examine the architecture and the security framework underlying the Android operating system. We explore existing Android end-to-end encrypted (E2EE) messaging applications and derive four categories of common issues that are applicable to these applications. We then provide an overview of the known issue of privilege escalation wherein a malicious privileged application can utilize inter-process communication techniques to send protected data to an unauthorized application on a user’s device. We demonstrate through a proof of concept how this behavior can be achieved in real
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Vedder, Benjamin. "Testing Safety-Critical Systems using Fault Injection and Property-Based Testing." Licentiate thesis, Högskolan i Halmstad, Centrum för forskning om inbyggda system (CERES), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-28173.

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Testing software-intensive systems can be challenging, especially when safety requirements are involved. Property-Based Testing (PBT) is a software testing technique where properties about software are specified and thousands of test cases with a wide range of inputs are automatically generated based on these properties. PBT does not formally prove that the software fulfils its specification, but it is an efficient way to identify deviations from the specification. Safety-critical systems that must be able to deal with faults, without causing damage or injuries, are often tested using Fault In
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Shpak, Yuliia. "Sledovaní současného stavu testovacích technik ve vybrané společnosti." Master's thesis, Vysoké učení technické v Brně. Fakulta podnikatelská, 2020. http://www.nusl.cz/ntk/nusl-417645.

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S vývojem informací, komunikací a technologií se moderní průmyslové řídicí systémy (ICS) potýkají čím dál více s otázkami automatického testováni pro zabezpečení stability a bezpečnosti systému. Z tohoto důvodu se testování stalo jednou z nejdůležitějších částí životního cyklu všech softwarů. V této diplomové práci budu zvažovat možnost využití stávajících zkušebních metod a nástrojů pro získání dostatečné jakosti a bezpečnosti softwaru v kontinuálních integračních systémech.
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19

Floquet, Julien. "Mécanismes auto-organisants pour connexions de bout en bout." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLC102/document.

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Les réseaux de cinquième génération sont en cours de définition et leurs différentes composantes commencent à émerger: nouvelles technologies d'accès à la radio, convergence fixe et mobile des réseaux et virtualization.Le contrôle et la gestion de bout en bout (E2E) du réseau ont une importance particulière pour les performances du réseau. Cela étant, nous segmentons le travail de thèse en deux parties: le réseau d’accès radio (RAN) axé sur la technologie MIMO Massif (M-MIMO) et la connexion E2E du point de vue de la couche transport.Dans la première partie, nous considérons la formation de fa
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Masum, Md Ebna, and Md Jewel Babu. "End-to-End Delay Performance Evaluation for VoIP in the LTE network." Thesis, Blekinge Tekniska Högskola, Sektionen för ingenjörsvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-4264.

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Long Term Evolution (LTE) is the last step towards the 4th genera-tion of cellular networks. This revolution is necessitated by the un-ceasing increase in demand for high speed connection on LTE net-works. This thesis mainly focuses on performance evaluation of end-to end delay (E2E) for VoIP in the LTE networks. In the course of E2E performance evaluation, simulation approach is realized using simulation tool OPNET 16.0. Three scenarios have been created. The first one is the baseline network while among other two, one consists of VoIP traffic solely and the other consisted of FTP along with
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Chebbo, Manal. "Simulation fine d'optique adaptative à très grand champ pour des grands et futurs très grands télescopes." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM4733/document.

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La simulation fine de systèmes d'OA à grand champ de type MOAO ou LTAO pour l'ELT se heurte à deux problématiques: l'augmentation du nombre de degrés de liberté du système. Cette augmentation rend les codes de simulation classiques peu utilisables, en particulier en ce qui concerne les processus d'inversion et de calcul matriciel. La complexité des systèmes, combinant EGL et EGN, grands miroirs déformables couvrant tout le champs et des miroirs dédiés dans les instruments eux mêmes, des rotations différentielles de pupille et ou de champs. Cette complexité conduit aux développements de procédu
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Gajdár, Matúš. "Nízko-dimenzionální faktorizace pro "End-To-End" řečové systémy." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2020. http://www.nusl.cz/ntk/nusl-417297.

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The project covers automatic speech recognition with neural network training using low-dimensional matrix factorization. We are describing time delay neural networks with factorization (TDNN-F) and without it (TDNN) in Pytorch language. We are comparing the implementation between Pytorch and Kaldi toolkit, where we achieve similar results during experiments with various network architectures. The last chapter describes the impact of a low-dimensional matrix factorization on End-to-End speech recognition systems and also a modification of the system with TDNN(-F) networks. Using specific networ
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Liviero, Filippo. "La modulazione dei canali transient receptor potential v1 e a1 con prostaglandina-e2e bradichinina è associata adaumento della risposta tussigena alla capsaicina ed a variazionidella regolazioneautonomica del ritmo cardiaco in soggetti sani." Doctoral thesis, Università degli studi di Padova, 2019. http://hdl.handle.net/11577/3425778.

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BACKGROUND: Vi sono evidenze in modelli animali che l’inalazione di particolato fine (PM), attivi i recettori polmonari TRPV1 e TRPA1 e attraverso una modulazione del sistema nervoso centrale possa influenzare la regolazione autonomica dell'attività cardiaca. Questa ipotetica via neurogena, potrebbe essere responsabile degli effetti cardiovascolari avversi osservati in soggetti suscettibili dopo esposizioni acute a PM. OBIETTIVI: Verificare che l'attività di TRPV1 e TRPA1 può essere modulata in vivo dall’inalazione di prostaglandina-E2 (PGE2) e bradichinina (BK), e che i cambiamenti nell'
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Omerdic, Edin. "Thruster fault diagnosis and accommodation for overactuated open-frame underwater vehicles." Thesis, University of South Wales, 2004. https://pure.southwales.ac.uk/en/studentthesis/thruster-fault-diagnosis-and-accommodation-for-overactuated-openframe-underwater-vehicles(d010b243-e2ee-4a12-9ff0-037c9e1af958).html.

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The work presented in the thesis concerns the design and development of a novel thruster fault diagnosis and accommodation system (PDAS) for overactuated, open-frame underwater vehicles. The remotely operated vehicles (ROVs) considered in this thesis have four thrusters for motion in the horizontal plane with three controllable degrees of freedom (DoF). Due to the redundancy resulting from this configuration, for the case of a partial fault or a total fault in a single thruster it is possible to reallocate control among operable thrusters in order that the ROV pilot is able to maintain control
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Alessandrini, Aduer. "'il 730 online' di CAF ACLI e l'introduzione di una cultura DevOps." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/17699/.

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In questo presente sempre più servizi che caratterizzano il nostro quotidiano (trasporti, utenze, commercio eccetera) stanno avendo una progressiva sostituzione della componente di interazione personale, in favore di una maggiore integrazione con la rete. Basti pensare a come grazie ad una connessione Internet, sia possibile monitorare in tempo reale il ritardo di un treno, o ordinare e ricevere a domicilio un piatto cucinato espressamente o vedere la sbarra del casello autostradale alzarsi perché il sistema ha riconosciuto la targa inserita poco prima tramite l'apposita app. In contesti come
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Ridge, Liam. "Investigating the role of Myh10 in the epicardium : insights from the EHC mouse." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/investigating-the-role-of-myh10-in-the-epicardium-insights-from-the-ehc-mouse(7d7cec65-e2e6-448c-a6d1-65d3fdc50f3e).html.

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Aim: Recent interest in cardiogenesis has focused on the epicardium, the outer epithelial layer that envelops the heart. Epicardial-derived cells (EPDCs) contribute vascular smooth muscle to developing coronary vessels and provide critical signalling cues to facilitate myocardial functionality. However, the precise molecular mechanisms that underpin epicardial biology remain unclear. Ablation of Myh10 in the EHC mouse results in embryonic lethal cardiac malformations, including epicardial and coronary defects. We sought to establish the role of Myh10 in epicardial cell function to further diss
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Di, Gioacchino Fabio. "Characterization of mesoscopic crystal plasticity from high-resolution surface displacement and lattice orientation mappings." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/characterization-of-mesoscopic-crystal-plasticity-from-highresolution-surface-displacement-and-lattice-orientation-mappings(77c47c76-e2ee-44ff-bdef-c53e25bb6bc1).html.

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Being able to predict the evolution of plastic deformation at the microstructural scale is of paramount importance in the engineering of materials for advanced applications. However, this is not straightforward because of the multiscale nature of deformation heterogeneity, both in space and time . The present thesis combines four related studies in a coherent work, which is aimed to develop experimental methods for studying crystal plasticity at the micro and mesoscale. A novel methodology for gold remodelling is initially proposed and used to apply high-density speckle patterns on the surface
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Alkahtani, Abdullah. "Mechanisms by which Staphylococcus aureus induces cytokines and cell death in human keratinocytes and mouse fibroblasts." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/mechanisms-by-which-staphylococcus-aureus-induces-cytokines-and-cell-death-in-human-keratinocytes-and-mouse-fibroblasts(d34b182e-e2e3-440f-af1f-47b43d0d5196).html.

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Background: Staphylococcus aureus is an important trigger of flares in atopic dermatitis. The exact mechanisms by which S. aureus induces inflammatory responses and cell death in the skin epithelium is unclear. The aim of this thesis was to elucidate the cellular and molecular mechanisms by which S. aureus induces it's pathogenic effects on keratinocyte and fibroblast cell lines. Methods: Human keratinocytes (HEKa), and mouse embryonic fibroblasts (MEF) from the NC/Nga dermatitis prone mouse strain were used to investigate the induction of Th2-promoting cytokines (IL-33 and TSLP) and cell deat
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Serra, Ana Paula Gonçalves. "Método para identificação de parâmetros de qualidade de serviços aplicados a serviços móveis e interativos." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/3/3141/tde-26072007-175442/.

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Atualmente, os usuários desejam obter, fornecer, compartilhar e interagir com informações e serviços com conteúdo multimídia em qualquer lugar, a qualquer momento e com qualquer dispositivo. Para que isso seja possível, um dos grandes desafios é assegurar a QoS (Quality of Service) fim a fim (entre o usuário final e a organização provedora de serviço) para a disponibilização de serviços móveis e interativos com conteúdo multimídia para os usuários finais. Em geral esse tipo de serviço têm maior exigência de QoS, pois além dos parâmetros de redes, possuem parâmetros específicos para áudio, imag
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Direito, Pedro Miguel Mimoso. "Decomposição da latência por segmento numa rede móvel de banda larga." Master's thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/12860.

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Mestrado em Engenharia Eletrónica e Telecomunicações<br>As redes 3GPP de banda larga móvel têm vindo disponibilizar velocidades de transmissão cada vez mais elevadas. Com a introdução das modernas redes de 4G/LTE essas velocidades situam-se agora nos 150 Mbps. Ao mesmo tempo, a saturação no número de subscritores e a facilidade com que estes podem mudar de provedor de serviço, fez com que a retenção dos mesmos fosse algo da maior importância para o sucesso financeiro de um operador móvel. A atenção dada à experiência de serviço, em todos os seus quadrantes, indo do humano ao técnico, e
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Chebbo, Manal. "SIMULATION FINE D'OPTIQUE ADAPTATIVE A TRES GRAND CHAMP POUR DES GRANDS ET FUTURS TRES GRANDS TELESCOPES." Phd thesis, Aix-Marseille Université, 2012. http://tel.archives-ouvertes.fr/tel-00742873.

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La simulation fine de systèmes d'OA a grand champ de type MOAO, MCAO ou LTAO pour l'ELT se heurte a deux problématiques: L'augmentation du nombre de degrés de liberté du système (au carre du diamètre du télescope). Cette augmentation rend les codes de simulation classiques peu (ou pas) utilisables, en particulier en ce qui concerne les processus d'inversion et de calcul matriciel. Il faut donc envisager des approches d'inversion itératives d'un modèle direct y = A * x en s'appuyant sur les théories d'optimisation a base de matrices creuses. La complexite des systèmes, combinant des étoiles nat
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Clark, Jeremy. "Democracy Enhancing Technologies: Toward deployable and incoercible E2E elections." Thesis, 2011. http://hdl.handle.net/10012/5992.

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End-to-end verifiable election systems (E2E systems) provide a provably correct tally while maintaining the secrecy of each voter's ballot, even if the voter is complicit in demonstrating how they voted. Providing voter incoercibility is one of the main challenges of designing E2E systems, particularly in the case of internet voting. A second challenge is building deployable, human-voteable E2E systems that conform to election laws and conventions. This dissertation examines deployability, coercion-resistance, and their intersection in election systems. In the course of this study, we introduc
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Sullivan, Michael Lee. "Biochemical and molecular characterization of ubiquitin carrier proteins (E2s) from higher plants." 1991. http://catalog.hathitrust.org/api/volumes/oclc/25684042.html.

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Yampolskiy, Mark [Verfasser]. "Maßnahmen zur Sicherung von E2E-QoS bei verketteten Diensten / vorgelegt von Mark Yampolskiy." 2009. http://d-nb.info/100005196X/34.

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Hong, Jenny (Hong). "Structural and Functional Relationships between Ubiquitin Conjugating Enzymes (E2s) and Ubiquitin Ligases (E3s)." Thesis, 2013. http://hdl.handle.net/1807/35799.

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The first part of the thesis describes a systematic function analysis that identified in vitro E2 partners for ten different HECT E3 ligase proteins. Using mass spectrometry, the linkage composition for the resulting autoubiquitylation products of a number of functional E2-HECT pairs was determined. HECT domains from different subfamilies catalyze the formation of very different types of Ub chains, largely independent of the E2 in the reaction. The second part of the thesis describes the characterization of the RAD6-interactome. Using affinity purification coupled with mass spectrometry, I id
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Ho, Jeremy. "BXE2E: a bidirectional transformation approach for medical record exchange." Thesis, 2017. http://hdl.handle.net/1828/7988.

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Modern health care systems are information dense and increasingly relying on computer-based information systems. Regrettably, many of these information systems behave only as an information repository, and the interoperability between different systems remains a challenge even with decades of investment in health information exchange standards. Medical records are complex data models and developing medical data import / export functions a is difficult, prone to error and hard to maintain process. Bidirectional transformations (bx) theories have been developed within the last decade in the fiel
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Марчук, Максим Денисович. "Реалізація Webmail сервісу". Магістерська робота, 2021. https://dspace.znu.edu.ua/jspui/handle/12345/6087.

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Марчук М. Д. Реалізація Webmail сервісу : кваліфікаційна робота магістра спеціальності 121 "Інженерія програмного забезпечення" / наук. керівник В. І. Горбенко. Запоріжжя : ЗНУ, 2021. 44 с.<br>UA : Робота викладена на 44 сторінках друкованого тексту, містить 30 рисунків, 11 джерел. Об’єкт дослідження: реалізація Webmail сервісу. Мета дослідження: розробка клієнтської програми електронної пошти у веб-браузері. Методи дослідження: методи об’єктно-орієнтованого програмування. В даній роботі висвітлюються етапи розробки Webmail сервісу. Під час збору даних були оброблені методичні матеріали повико
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